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<entry dataset="TrEMBL" created="2016-06-08" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4J4</accession>
    <name>A0A151V4J4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 17">Alpha-amylase</fullName>
            <ecNumber evidence="4 17">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MGG_10209</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4 17"/>
    <dbReference type="EMBL" id="JH165177">
        <property type="protein sequence ID" value="KYQ30500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846004.1">
        <property type="nucleotide sequence ID" value="XM_016990483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4J4"/>
    <dbReference type="SMR" id="A0A151V4J4"/>
    <dbReference type="STRING" id="242507.A0A151V4J4"/>
    <dbReference type="GeneID" id="2681856"/>
    <dbReference type="KEGG" id="mgr:MGG_10209"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10209"/>
    <dbReference type="InParanoid" id="A0A151V4J4"/>
    <dbReference type="OrthoDB" id="204980at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11319">
        <property type="entry name" value="AmyAc_euk_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000120">
        <property type="entry name" value="Alpha-amylase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013777">
        <property type="entry name" value="A-amylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF212">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001024">
        <property type="entry name" value="Alph-amyl_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 17" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007589987" description="Alpha-amylase" evidence="18">
        <location>
            <begin position="20"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="19">
        <location>
            <begin position="495"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="12">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="159"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001024-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KYQ30500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="567" mass="61347" checksum="23DFB498DAB18BE5" modified="2016-06-08" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-03-18" modified="2025-04-09" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4RE46</accession>
    <accession>G4NEK3</accession>
    <name>DRE2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fe-S cluster assembly protein DRE2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Anamorsin homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">DRE2</name>
        <name type="ORF">MGG_00776</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Interacts with TAH18. Interacts with MIA40.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anamorsin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718217.1">
        <property type="nucleotide sequence ID" value="XM_003718169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RE46"/>
    <dbReference type="STRING" id="242507.A4RE46"/>
    <dbReference type="EnsemblFungi" id="MGG_00776T0">
        <property type="protein sequence ID" value="MGG_00776T0"/>
        <property type="gene ID" value="MGG_00776"/>
    </dbReference>
    <dbReference type="GeneID" id="2675040"/>
    <dbReference type="KEGG" id="mgr:MGG_00776"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00776"/>
    <dbReference type="eggNOG" id="KOG4020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067152_1_0_1"/>
    <dbReference type="InParanoid" id="A4RE46"/>
    <dbReference type="OMA" id="DFVMPVT"/>
    <dbReference type="OrthoDB" id="311633at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11000">
        <property type="entry name" value="Fe-S cluster assembly protein Dre2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03115">
        <property type="entry name" value="Anamorsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007785">
        <property type="entry name" value="Anamorsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046408">
        <property type="entry name" value="CIAPIN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031838">
        <property type="entry name" value="Dre2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273:SF14">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05093">
        <property type="entry name" value="CIAPIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16803">
        <property type="entry name" value="DRE2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0001">2Fe-2S</keyword>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000324866" description="Fe-S cluster assembly protein DRE2">
        <location>
            <begin position="1"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal SAM-like domain" evidence="1">
        <location>
            <begin position="17"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="1">
        <location>
            <begin position="145"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Fe-S binding site A" evidence="1">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Fe-S binding site B" evidence="1">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cx2C motif 1" evidence="1">
        <location>
            <begin position="290"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Cx2C motif 2" evidence="1">
        <location>
            <begin position="301"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="327" mass="34228" checksum="14B6CD8789822207" modified="2007-05-15" version="1">MSPATVTIDTTPDFSNGGAPHSTLLLAPPAMAAQQDAMAAALTDAAPLGSRPELYMLDRLAAGLTNLAPAAYDLVLVLASGADPLLSRRDVFAKIADAMKPGAKLRSRDGSPLDAAIAKEAILAGLVESAEGAYEKPAEEVAAVPLKFLKKKNKGEGGGPVQSPAAATQPTAPAPAAAAKSLPNGVVMVDLNDDFDVSDDEMIDEDELMTEEDLMRPIQQPPECAPKPGKKRRACKDCTCGLAERLEAQDKARRDKADKQLQEKAATPFKLASEDLNELDFTVQGKTGSCGSCALGDAFRCADCPYIGLPAFKPGEEVTILNNVAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKT0</accession>
    <name>G4MKT0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709382.1">
        <property type="nucleotide sequence ID" value="XM_003709334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKT0"/>
    <dbReference type="SMR" id="G4MKT0"/>
    <dbReference type="STRING" id="242507.G4MKT0"/>
    <dbReference type="GeneID" id="2684849"/>
    <dbReference type="KEGG" id="mgr:MGG_06676"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06676"/>
    <dbReference type="eggNOG" id="KOG0393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_21_4_1"/>
    <dbReference type="InParanoid" id="G4MKT0"/>
    <dbReference type="OMA" id="GERIPVM"/>
    <dbReference type="OrthoDB" id="25896at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21701" checksum="B8A3C85BA4C07FC4" modified="2011-12-14" version="1">MESHTITVLLLGDDRTGKSTFLSRVAQGKDRLTGRAEITLLRDSDQPFFFELRSRKGVYRIEFHDTSGPTNWRLLQPDLIVICYDISQRLSLINMQRVWIKELRQTFPAGDSIPIAVLGLKRDLRSEEDPNGIIYPQEGYRISQEMRADRYMECSAVTGELLSETFEDLYLMAVKTTTAEGGQSEGACAIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLM4</accession>
    <name>G4MLM4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_06755</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709469.1">
        <property type="nucleotide sequence ID" value="XM_003709421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLM4"/>
    <dbReference type="GeneID" id="2684928"/>
    <dbReference type="KEGG" id="mgr:MGG_06755"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06755"/>
    <dbReference type="eggNOG" id="ENOG502SKG6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_6_3_1"/>
    <dbReference type="InParanoid" id="G4MLM4"/>
    <dbReference type="OMA" id="ANQTCIC"/>
    <dbReference type="OrthoDB" id="2496787at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="14" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 17" id="KW-0732">Signal</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465230" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="20"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="6"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="445"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="34"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA56857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="558" mass="61276" checksum="7CDE894182CE39B6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLN4</accession>
    <name>G4MLN4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_06764</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709479.1">
        <property type="nucleotide sequence ID" value="XM_003709431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLN4"/>
    <dbReference type="SMR" id="G4MLN4"/>
    <dbReference type="FunCoup" id="G4MLN4">
        <property type="interactions" value="555"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MLN4"/>
    <dbReference type="GeneID" id="2684937"/>
    <dbReference type="KEGG" id="mgr:MGG_06764"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06764"/>
    <dbReference type="eggNOG" id="KOG0707">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001715_0_1_1"/>
    <dbReference type="InParanoid" id="G4MLN4"/>
    <dbReference type="OMA" id="EWAVVHG"/>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:GMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000776">
        <property type="entry name" value="Guanylate kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117:SF13">
        <property type="entry name" value="GUANYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117">
        <property type="entry name" value="GUANYLATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="56"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA56867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="242" mass="27224" checksum="463047130F8FEEE7" modified="2011-12-14" version="1">MSKLGLPGLFRPASSLLRNGCNTTPFCNLPRHITRTASSSPTFTNARMSSTQPTDRRPLVICGPSGVGKGTLIQMLFQRHPETFTLSVSHTTRAPRPGEQDGVHYHYVTKEQFQALIAEDKFVEHAQFGSNNYGTSKATIEEQTAKGKVVVLDIEMEGVKQVKKSSISARYVFISPPSEEELEKRLRGRGTENEDSVNQRLNRAKEELAWSKTEKFDKVLVNDDLEKTFKELDEFVYEMPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMH0</accession>
    <name>G4MMH0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709560.1">
        <property type="nucleotide sequence ID" value="XM_003709512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMH0"/>
    <dbReference type="SMR" id="G4MMH0"/>
    <dbReference type="GeneID" id="12984554"/>
    <dbReference type="KEGG" id="mgr:MGG_16188"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16188"/>
    <dbReference type="HOGENOM" id="CLU_1777853_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMH0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465123" evidence="1">
        <location>
            <begin position="20"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="146" mass="16365" checksum="66D6050E2322CCD7" modified="2011-12-14" version="1">MRFTCLLLLCTATVHLGAASTLPKDFDASHCPKVKDFDASHCPKKVDPSLCPRRPGGTSCPANFDRSQCSAVLSNAGNHKRDLLVRREEPDLGRDLLCCCLDICLIFVNAWLDCLLEQQRMRGQPEAVRQAYRQGRHDAYFGAWWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN05</accession>
    <name>G4MN05_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein transporter sec73</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_06905</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709639.1">
        <property type="nucleotide sequence ID" value="XM_003709591.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MN05"/>
    <dbReference type="STRING" id="242507.G4MN05"/>
    <dbReference type="GeneID" id="2685078"/>
    <dbReference type="KEGG" id="mgr:MGG_06905"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06905"/>
    <dbReference type="eggNOG" id="KOG0929">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004694_0_0_1"/>
    <dbReference type="InParanoid" id="G4MN05"/>
    <dbReference type="OMA" id="FVRHNAL"/>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF405">
        <property type="entry name" value="ARF GUANINE NUCLEOTIDE EXCHANGE FACTOR SYT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="4">
        <location>
            <begin position="472"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="762"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1055"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1306"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="946"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="256"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="273"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="460"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1062"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
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            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1144"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1176"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1223"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1323"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1390"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1457"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1504"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1514"/>
            <end position="1529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA57027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1529" mass="168049" checksum="D97F28A4968DBDB0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN27</accession>
    <name>G4MN27_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05577</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710453.1">
        <property type="nucleotide sequence ID" value="XM_003710405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN27"/>
    <dbReference type="SMR" id="G4MN27"/>
    <dbReference type="GeneID" id="2676057"/>
    <dbReference type="KEGG" id="mgr:MGG_05577"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05577"/>
    <dbReference type="eggNOG" id="ENOG502SJKK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019706_0_0_1"/>
    <dbReference type="InParanoid" id="G4MN27"/>
    <dbReference type="OMA" id="TAHSPAY"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058664">
        <property type="entry name" value="ARB_00930-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051478">
        <property type="entry name" value="Beta-lactamase-like_AB/R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935:SF97">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22935">
        <property type="entry name" value="PENICILLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26335">
        <property type="entry name" value="ARB_00930_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012271662" evidence="1">
        <location>
            <begin position="16"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="71"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-like ARB-00930-like C-terminal" evidence="3">
        <location>
            <begin position="432"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="584" mass="62162" checksum="0506B45EF849594E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN90</accession>
    <name>G4MN90_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Azaphilone pigments biosynthesis cluster protein L N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02064</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708825.1">
        <property type="nucleotide sequence ID" value="XM_003708777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN90"/>
    <dbReference type="SMR" id="G4MN90"/>
    <dbReference type="STRING" id="242507.G4MN90"/>
    <dbReference type="GeneID" id="2681219"/>
    <dbReference type="KEGG" id="mgr:MGG_02064"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02064"/>
    <dbReference type="eggNOG" id="ENOG502SICT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032923_0_1_1"/>
    <dbReference type="InParanoid" id="G4MN90"/>
    <dbReference type="OMA" id="QCMNVVA"/>
    <dbReference type="OrthoDB" id="5068804at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031348">
        <property type="entry name" value="PigL_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17111">
        <property type="entry name" value="PigL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Azaphilone pigments biosynthesis cluster protein L N-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="402" mass="44253" checksum="049A1B2C5A99BFE4" modified="2011-12-14" version="1">MTDPLSTASGVVALVTFALQSSVTLHRTIRSLRSQEKDARALKDELADLTSVLETLLETIEGHPNIDFGSLALPLQRCGKTCQEYGELIAKCTRHSTSSRASLRDWITQRYLQGDINDFRNMLSGYKSTINIALANANIRFAAITPQVLEDYKDLILDTTLDLKEHLESLEEKVGDLQDSIPQDDEAEWEALSEEKESTEQGLKLCAQLSAQIEQFMSLSAENPQFSSRPSAHKHIKSGLGPVGASLQSLLLILQKHESSIKQQMEALRVSGLHGDATAQIESLEETKTAIRQCIHVVSDADETVREERRNVFADITMADDSYAFSVSTVGDLVTARGFHLSGRARHVGGQISDESYQMTVDALTKLDLAHSQSTRQNSQDHGQKTHGPTPVHPETGGTKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNA0</accession>
    <name>G4MNA0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cryptochrome-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_02071</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708836.1">
        <property type="nucleotide sequence ID" value="XM_003708788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNA0"/>
    <dbReference type="STRING" id="242507.G4MNA0"/>
    <dbReference type="GeneID" id="2681226"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02071"/>
    <dbReference type="eggNOG" id="KOG0133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010348_3_3_1"/>
    <dbReference type="InParanoid" id="G4MNA0"/>
    <dbReference type="OMA" id="GNWNYTA"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF9">
        <property type="entry name" value="CRYPTOCHROME CIRCADIAN CLOCK 5 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="608"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="650"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="277"/>
            <end position="281"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA56224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="679" mass="76303" checksum="A8462A06D478993B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP47</accession>
    <name>G4MP47_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_02142</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708918.1">
        <property type="nucleotide sequence ID" value="XM_003708870.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MP47"/>
    <dbReference type="STRING" id="242507.G4MP47"/>
    <dbReference type="GeneID" id="2681265"/>
    <dbReference type="KEGG" id="mgr:MGG_02142"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02142"/>
    <dbReference type="eggNOG" id="ENOG502S7G0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_256978_0_0_1"/>
    <dbReference type="InParanoid" id="G4MP47"/>
    <dbReference type="OMA" id="TSPXTSP"/>
    <dbReference type="OrthoDB" id="1193027at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47849">
        <property type="entry name" value="CHITIN-BINDING LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47849:SF8">
        <property type="entry name" value="LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465258" description="Chitin-binding type-1 domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="6">
        <location>
            <begin position="29"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="6">
        <location>
            <begin position="103"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="6">
        <location>
            <begin position="174"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="288"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="581"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="874"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1132"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="288"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="581"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="723"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="737"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="106"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="177"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA56306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1361" mass="133725" checksum="9668783B42D7AF1A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPF7</accession>
    <name>G4MPF7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ethanolamine kinase</fullName>
            <ecNumber evidence="3">2.7.1.82</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_05713</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.82" evidence="3"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710612.1">
        <property type="nucleotide sequence ID" value="XM_003710564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPF7"/>
    <dbReference type="SMR" id="G4MPF7"/>
    <dbReference type="STRING" id="242507.G4MPF7"/>
    <dbReference type="GeneID" id="2675909"/>
    <dbReference type="KEGG" id="mgr:MGG_05713"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05713"/>
    <dbReference type="eggNOG" id="KOG4720">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012712_1_1_1"/>
    <dbReference type="InParanoid" id="G4MPF7"/>
    <dbReference type="OMA" id="FALIPKY"/>
    <dbReference type="OrthoDB" id="10267235at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF66">
        <property type="entry name" value="ETHANOLAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="199"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA58000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="449" mass="50647" checksum="F588E00A3E09126C" modified="2011-12-14" version="1">MAKSAVVEANGHHTTTANNQCNNNAIPKDPAIGPAQSENHKILFLNLRYRGDDAETSNASATALIQKLRPDWGSEIDFRRFTDGITNTLLQARPRHAEPLPGESQDDARDREAILLRAYGNGTDLIIDRNREAQNHELLSRHRLAPELLALFENGMLYRFIRGRVTAPQDLRRPEIYRAVARRLAQWHSTIPCLPMPKKQQQAQSTTNGGQTRIDEMVPGKLQPNVWTVMQKWILALPTETSAQRERQTSLQKELDRVVAEFGQRPGLGHDGLVFAHCDLLSGNVIVLPKPAATAKSPAAANSADVSVTFIDYEYATPSPAAFDLANHFAEWGGFDCDFSVLPTRAQRREFIREYIRVYFGNGGGDEDDHEDAAEDLFAEVDVYRGLPGFYWGIWALIQATISTIDFDYASYAETRLGEYWAWRAEQDGSRVKEGREMPLRERRWAQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPL2</accession>
    <name>G4MPL2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enterotoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708973.1">
        <property type="nucleotide sequence ID" value="XM_003708925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPL2"/>
    <dbReference type="SMR" id="G4MPL2"/>
    <dbReference type="GeneID" id="12984292"/>
    <dbReference type="KEGG" id="mgr:MGG_16059"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16059"/>
    <dbReference type="HOGENOM" id="CLU_1475451_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPL2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.210.10">
        <property type="entry name" value="Heat-Labile Enterotoxin, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465274" description="Enterotoxin" evidence="1">
        <location>
            <begin position="22"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20752" checksum="34FD4620C6E763CA" modified="2011-12-14" version="1">MLRSWLVHSSILLSFLGQTSATFEECKKGLVYRGDWRSPQQVFKSGFSDGKNPYTPSNDQIDLTYVSVAKSVPHAKEYAKSHKPSLQLCSYVYRINVEGLDCVPFGIVKSMYKRRRIPNNFPDEQGHAIIDSLPWSNVEGWIQVCPFAKYHERRWVANPDKEKGSKFDALRLPAAQSTAAQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR43</accession>
    <name>G4MR43_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Molybdopterin synthase sulfur carrier subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Common component for nitrate reductase and xanthine dehydrogenase protein G</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor synthesis protein 2 small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor synthesis protein 2A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfur carrier protein MOCS2A</fullName>
            <shortName evidence="5">MOCS2A</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cnxG</name>
        <name evidence="6" type="ORF">MGG_09893</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaD family. MOCS2A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709987.1">
        <property type="nucleotide sequence ID" value="XM_003709939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR43"/>
    <dbReference type="SMR" id="G4MR43"/>
    <dbReference type="STRING" id="242507.G4MR43"/>
    <dbReference type="GeneID" id="2680937"/>
    <dbReference type="KEGG" id="mgr:MGG_09893"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09893"/>
    <dbReference type="eggNOG" id="ENOG502SD3I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114601_6_1_1"/>
    <dbReference type="InParanoid" id="G4MR43"/>
    <dbReference type="OMA" id="IECNDEV"/>
    <dbReference type="OrthoDB" id="5595860at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990133">
        <property type="term" value="C:molybdopterin adenylyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990140">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030366">
        <property type="term" value="F:molybdopterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00754">
        <property type="entry name" value="Ubl_MoaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03051">
        <property type="entry name" value="MOCS2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044672">
        <property type="entry name" value="MOCS2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028887">
        <property type="entry name" value="MOCS2A_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359:SF1">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="1-thioglycine; alternate" evidence="5">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycyl adenylate; alternate" evidence="5">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA57375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="100" mass="10586" checksum="71FB9EDD23CED7C2" modified="2011-12-14" version="1">MASLPRAPPGHFNILYFASASSFTSKGSESLPAPLPLSKLFSVLEERYSGIKAKILDSCLVTVNLNYVDMPSDQDSGDDGNQLIISEGDEVAIIPPVSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSL7</accession>
    <name>G4MSL7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tafazzin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714440.1">
        <property type="nucleotide sequence ID" value="XM_003714392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSL7"/>
    <dbReference type="STRING" id="242507.G4MSL7"/>
    <dbReference type="GeneID" id="2679672"/>
    <dbReference type="KEGG" id="mgr:MGG_01478"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01478"/>
    <dbReference type="eggNOG" id="ENOG502S698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032824_1_0_1"/>
    <dbReference type="InParanoid" id="G4MSL7"/>
    <dbReference type="OMA" id="GTNYYSH"/>
    <dbReference type="OrthoDB" id="5278911at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="53476" checksum="3550B26536F402C7" modified="2011-12-14" version="1">MPKKRHQTHYSKPPSTPPPSLASSRIRSADSDAQTKGVNELLADLRRVGVSNNGASPSTQITPIDAVLNPIPSVPPALRQVLRIPESPAPQQRSRRLVDAQGRRLPPGPPAPRSWLAQSRHAPTALKGKDHIGSCAVRGSDFFIHPLPGVNVPERGSLLDLALSTMVADWEYQRHYNQYWLYTLPDHLRLALICYLGSYRPNGASPGDLKRLLLPPPDLDPEDESPKMGHTPNEGIHTFDMVDGFGKATDLKELSDILFPRRPAEVTHFALQESWDAPADTWSAPMLVADVRPSLLPSLTRVSLAVNPSIAHKMSWKHLLSFSSHLATVTHLSLAYWPRPTLTPNAVASVIDSPSGSIQYGGTGFYSHSLDDDWTEAILLLRRLSKNLYGLEYLDVTGCASWTEALIRSVDHDSVDWQGAWGKITELLMYWGYRTPKADEEQKYSEFLGHIALATRVERHIIGKRSGRGRFVEVLRDAVPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT45</accession>
    <name>G4MT45_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Replication protein A 32 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07124</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715317.1">
        <property type="nucleotide sequence ID" value="XM_003715269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT45"/>
    <dbReference type="SMR" id="G4MT45"/>
    <dbReference type="FunCoup" id="G4MT45">
        <property type="interactions" value="873"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MT45"/>
    <dbReference type="GeneID" id="2683246"/>
    <dbReference type="KEGG" id="mgr:MGG_07124"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07124"/>
    <dbReference type="eggNOG" id="KOG3108">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051033_0_1_1"/>
    <dbReference type="InParanoid" id="G4MT45"/>
    <dbReference type="OMA" id="SFGNKRY"/>
    <dbReference type="OrthoDB" id="25571at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014646">
        <property type="entry name" value="Rfa2/RPA32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036949">
        <property type="entry name" value="RPA32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB" evidence="7">
        <location>
            <begin position="77"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A C-terminal" evidence="8">
        <location>
            <begin position="170"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="275" mass="29153" checksum="AE2B3C4F302B649B" modified="2011-12-14" version="1">MTSYGGNNFSRTGYNAQGAEDGGGFMGGSQQGSQGGPGGKSYQDECLKPVTVKQLLDVQAPYPDADFLLDGRAITQITLVGQVRSINPQPTNITYRIDDGTGTIDVKRWIDPEKAEDADAASQHQPDSYVRVWGKLKAFNNRRHVGALFVRPVEDFNEVNYHMLEVAYVHLDAVRQSSGGGGGAGGGGDDNMFVDSYGGGGGGGGSKAANCSTNAQRLFNHLQNSSAGNEGLEANIIARGINMSVRDVEAAADELLSAGLIYPTVDDHTWATLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTL8</accession>
    <name>G4MTL8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Rhizopuspepsin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_07179</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715383.1">
        <property type="nucleotide sequence ID" value="XM_003715335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTL8"/>
    <dbReference type="SMR" id="G4MTL8"/>
    <dbReference type="STRING" id="242507.G4MTL8"/>
    <dbReference type="MEROPS" id="A01.077"/>
    <dbReference type="GeneID" id="2683162"/>
    <dbReference type="KEGG" id="mgr:MGG_07179"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07179"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_10_1_1"/>
    <dbReference type="InParanoid" id="G4MTL8"/>
    <dbReference type="OMA" id="AASNTWV"/>
    <dbReference type="OrthoDB" id="660550at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000085">
        <property type="entry name" value="Aspartic-type endopeptidase (CtsD), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000060">
        <property type="entry name" value="Aspartic-type endopeptidase ctsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF75">
        <property type="entry name" value="ENDOPEPTIDASE (CTSD), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465314" evidence="14">
        <location>
            <begin position="19"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="15">
        <location>
            <begin position="129"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="83"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="436"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="442"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="160"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA55576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="523" mass="55273" checksum="7D90286B79ECE41C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUL6</accession>
    <name>G4MUL6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 19">ATP-dependent DNA helicase II subunit 2</fullName>
            <ecNumber evidence="4 19">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MGG_10157</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 19">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the ku80 family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4 19"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713796.1">
        <property type="nucleotide sequence ID" value="XM_003713748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUL6"/>
    <dbReference type="FunCoup" id="G4MUL6">
        <property type="interactions" value="128"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUL6"/>
    <dbReference type="GeneID" id="2681784"/>
    <dbReference type="KEGG" id="mgr:MGG_10157"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10157"/>
    <dbReference type="eggNOG" id="KOG2326">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010975_1_1_1"/>
    <dbReference type="InParanoid" id="G4MUL6"/>
    <dbReference type="OMA" id="WAMQYVW"/>
    <dbReference type="OrthoDB" id="30826at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043564">
        <property type="term" value="C:Ku70:Ku80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00873">
        <property type="entry name" value="KU80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000073">
        <property type="entry name" value="ATP-dependent DNA helicase II subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1600.10:FF:000002">
        <property type="entry name" value="X-ray repair cross-complementing protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.240">
        <property type="entry name" value="Ku, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024193">
        <property type="entry name" value="Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036494">
        <property type="entry name" value="Ku_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014893">
        <property type="entry name" value="Ku_PK_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF4">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08785">
        <property type="entry name" value="Ku_PK_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016570">
        <property type="entry name" value="Ku80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101420">
        <property type="entry name" value="C-terminal domain of Ku80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 19" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14 19" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="15 19" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13 19" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16 19" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="VWFA" evidence="20">
        <location>
            <begin position="6"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR016570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EHA53989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="726" mass="80944" checksum="4EC3B1F7CACFB85A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUX4</accession>
    <name>G4MUX4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715515.1">
        <property type="nucleotide sequence ID" value="XM_003715467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUX4"/>
    <dbReference type="STRING" id="242507.G4MUX4"/>
    <dbReference type="GeneID" id="2683184"/>
    <dbReference type="KEGG" id="mgr:MGG_07288"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07288"/>
    <dbReference type="eggNOG" id="ENOG502REK8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018589_1_0_1"/>
    <dbReference type="InParanoid" id="G4MUX4"/>
    <dbReference type="OMA" id="CPDIRKM"/>
    <dbReference type="OrthoDB" id="5405297at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="136"/>
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    </feature>
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            <end position="40"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <end position="686"/>
        </location>
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            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="686" mass="74539" checksum="D7F636056DF17CBB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV94</accession>
    <name>G4MV94_PYRO7</name>
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        <recommendedName>
            <fullName evidence="1">Sister chromatid cohesion protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="4" type="ORF">MGG_01726</name>
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    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCC2/Nipped-B family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_01726"/>
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    <dbReference type="HOGENOM" id="CLU_000901_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV94"/>
    <dbReference type="OMA" id="GSTDWPA"/>
    <dbReference type="OrthoDB" id="418242at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
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    <dbReference type="GO" id="GO:0090694">
        <property type="term" value="C:Scc2-Scc4 cohesin loading complex"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0140588">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034087">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071169">
        <property type="term" value="P:establishment of protein localization to chromatin"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024986">
        <property type="entry name" value="Nipped-B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033031">
        <property type="entry name" value="Scc2/Nipped-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704:SF18">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12830">
        <property type="entry name" value="Nipped-B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Sister chromatid cohesion C-terminal" evidence="3">
        <location>
            <begin position="1504"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        <location>
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        </location>
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        </location>
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    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1872"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1887"/>
            <end position="1918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1933" mass="212953" checksum="F59712DE0A794537" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVB8</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_01750</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714747.1">
        <property type="nucleotide sequence ID" value="XM_003714699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVB8"/>
    <dbReference type="GeneID" id="2679188"/>
    <dbReference type="KEGG" id="mgr:MGG_01750"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01750"/>
    <dbReference type="eggNOG" id="ENOG502SNDG">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_361708_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVB8"/>
    <dbReference type="OMA" id="IATPNYC"/>
    <dbReference type="OrthoDB" id="5420777at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465663" evidence="2">
        <location>
            <begin position="25"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="773" mass="78256" checksum="7B6B2E8CC31DB40A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW35</accession>
    <name>G4MW35_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 52A12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_08956</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713995.1">
        <property type="nucleotide sequence ID" value="XM_003713947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW35"/>
    <dbReference type="SMR" id="G4MW35"/>
    <dbReference type="STRING" id="242507.G4MW35"/>
    <dbReference type="GeneID" id="2679941"/>
    <dbReference type="KEGG" id="mgr:MGG_08956"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08956"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_27_0_1"/>
    <dbReference type="InParanoid" id="G4MW35"/>
    <dbReference type="OMA" id="RRWTEDP"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002974">
        <property type="entry name" value="Cyt_P450_E_CYP52_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF17">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01239">
        <property type="entry name" value="EP450IICYP52"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602402-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA54188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="509" mass="58420" checksum="3ECF9F42AAED3D4F" modified="2011-12-14" version="1">MSLSTIIAQVALALIASVWIWRSITLYYRRRKLKLLHGCMPVTKIPDWDPIFGLGFTYTLIKSDINNHRLINNTVERLQTYGYTHMANVMRHRMFFTCEPENLKAIMHGQFDHFDNELRSVPAGHFMGMGIFLADGEKWQRSRALVRPNFARDQVADLGSLERHFQILLSIIPKDGSAVDLAPLFFAFTMDSITDFLFGESVKALQAHASGAHASSSPWSQKGIEQFAEAWEYAQNDMLFRFILGPARYVYQDKKANQCVKMIHAHVDRYVEQAVRFRNEELARGGDEKEPKSEGRYIFLQALAKQTQDRKVLRDELMNLLMAGRDTTAALLSNLFHTFARRPDVWAKLKNEVMFLEGRLPTYEDIRNMKYVRWCINEFGILGKQASFDTTLPRGGGPNGRSPIFLPKGSIVLYSMLAQHRRKDLFGEDALEFRPERWETLRPGWNYVPFNGGPRICVGQQYALTEASYLVVRFVQTFATVESRDPEPWSIGKRLLTCPMNGTIVSLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW45</accession>
    <name>G4MW45_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714005.1">
        <property type="nucleotide sequence ID" value="XM_003713957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW45"/>
    <dbReference type="GeneID" id="12987355"/>
    <dbReference type="KEGG" id="mgr:MGG_15623"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15623"/>
    <dbReference type="HOGENOM" id="CLU_2543013_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW45"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="83" mass="8764" checksum="58FC87EABFCCE534" modified="2011-12-14" version="1">MPSIRVSGIDPPADGTSHSVLGSRPASWVGKKQAPQPLASREHLGNKRRQGARVGVGAQRDPVREVAVANSNFMQLLGLIVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWU8</accession>
    <name>G4MWU8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_08316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715759.1">
        <property type="nucleotide sequence ID" value="XM_003715711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWU8"/>
    <dbReference type="GeneID" id="2678571"/>
    <dbReference type="KEGG" id="mgr:MGG_08316"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08316"/>
    <dbReference type="HOGENOM" id="CLU_1644056_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWU8"/>
    <dbReference type="OMA" id="LCEHPLP"/>
    <dbReference type="OrthoDB" id="10509356at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="161" mass="18233" checksum="3DDE1ACA1F5FE9A4" modified="2011-12-14" version="1">MGQDPITSSPAYKTKNLSNQFNFLSNEANTIPSPGSDGRSHELALFREILCEHPLPVAAEYLAASELRSWVDSDRMVRDGKLVHFHVNYRIFTFSTTSPVESFQLNRAISKADASRVKNDDEWRQLPREINDAVRCYDERYPSLPVNGRTSGLYKPGKSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWV8</accession>
    <name>G4MWV8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715769.1">
        <property type="nucleotide sequence ID" value="XM_003715721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWV8"/>
    <dbReference type="STRING" id="242507.G4MWV8"/>
    <dbReference type="GeneID" id="2678501"/>
    <dbReference type="KEGG" id="mgr:MGG_08307"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08307"/>
    <dbReference type="eggNOG" id="KOG1256">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022749_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWV8"/>
    <dbReference type="OMA" id="ADWNIYT"/>
    <dbReference type="OrthoDB" id="4138492at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF11">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="156"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="305"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="570" mass="61365" checksum="B99EB57B6584EF3A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX03</accession>
    <name>G4MX03_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_01209</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714102.1">
        <property type="nucleotide sequence ID" value="XM_003714054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX03"/>
    <dbReference type="FunCoup" id="G4MX03">
        <property type="interactions" value="1781"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MX03"/>
    <dbReference type="GeneID" id="2679765"/>
    <dbReference type="KEGG" id="mgr:MGG_01209"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01209"/>
    <dbReference type="eggNOG" id="KOG4124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013026_2_0_1"/>
    <dbReference type="InParanoid" id="G4MX03"/>
    <dbReference type="OMA" id="STVQDMD"/>
    <dbReference type="OrthoDB" id="3269380at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="674"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="594"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="413"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="609"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="810" mass="87594" checksum="F1DFD531842059D6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXC7</accession>
    <name>G4MXC7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_08254</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715832.1">
        <property type="nucleotide sequence ID" value="XM_003715784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXC7"/>
    <dbReference type="SMR" id="G4MXC7"/>
    <dbReference type="STRING" id="242507.G4MXC7"/>
    <dbReference type="CAZy" id="AA9">
        <property type="family name" value="Auxiliary Activities 9"/>
    </dbReference>
    <dbReference type="GeneID" id="2678471"/>
    <dbReference type="KEGG" id="mgr:MGG_08254"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08254"/>
    <dbReference type="eggNOG" id="ENOG502RYSN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_4_2_1"/>
    <dbReference type="InParanoid" id="G4MXC7"/>
    <dbReference type="OMA" id="AVWFKVF"/>
    <dbReference type="OrthoDB" id="5271017at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF10">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012745548" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="16"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="17">
        <location>
            <begin position="29"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA56025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="229" mass="23982" checksum="045BECE83A48E2B8" modified="2011-12-14" version="1">MKLTLAIALVAAVTAAPSPAPHYTFPKLSGSADWQYIRKTANFQSNGPVTDVNSDAIRCYEAGSVGGTKTMNVQAGGQITFGAAPNIFHIGPLSGYMAKVPAGQTADRWDGKGAVWFKVYQEMPSGTQGGLQFASNNKGTVSFTIPMCIASGEYLFRVEHVALHGAGQMNGAQFYISCAQINVQGGAGSKTPSGLVSFPGAYKATDPGLLINIYNTNRYTPAGPAVFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXG4</accession>
    <name>G4MXG4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">P-type Na(+) transporter</fullName>
            <ecNumber evidence="19">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">MGG_10730</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:75815"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IID subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="19"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713301.1">
        <property type="nucleotide sequence ID" value="XM_003713253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXG4"/>
    <dbReference type="SMR" id="G4MXG4"/>
    <dbReference type="FunCoup" id="G4MXG4">
        <property type="interactions" value="39"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MXG4"/>
    <dbReference type="GeneID" id="2676260"/>
    <dbReference type="KEGG" id="mgr:MGG_10730"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10730"/>
    <dbReference type="eggNOG" id="KOG0202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_3_3_1"/>
    <dbReference type="InParanoid" id="G4MXG4"/>
    <dbReference type="OMA" id="PVQKDCD"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="PHI-base" id="PHI:2095"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008554">
        <property type="term" value="F:P-type sodium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02086">
        <property type="entry name" value="P-type_ATPase_Na_ENA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000015">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000020">
        <property type="entry name" value="Sodium ion P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000039">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000047">
        <property type="entry name" value="Sodium P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006414">
        <property type="entry name" value="P-type_ATPase_IID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01523">
        <property type="entry name" value="ATPase-IID_K-Na"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="17" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 23" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="332"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="797"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="834"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="875"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="922"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="973"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="1006"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="24">
        <location>
            <begin position="28"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1071"/>
            <end position="1094"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00035017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EHA53494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1094" mass="119758" checksum="BC7D6A1FACB8D52F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXG7</accession>
    <name>G4MXG7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10727</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713304.1">
        <property type="nucleotide sequence ID" value="XM_003713256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXG7"/>
    <dbReference type="STRING" id="242507.G4MXG7"/>
    <dbReference type="GeneID" id="2676257"/>
    <dbReference type="KEGG" id="mgr:MGG_10727"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10727"/>
    <dbReference type="eggNOG" id="ENOG502SQ11">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_493500_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXG7"/>
    <dbReference type="OMA" id="YETIVIW"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Znf_C2H2_type"/>
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    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
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            <begin position="515"/>
            <end position="543"/>
        </location>
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            <begin position="1"/>
            <end position="47"/>
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        <location>
            <begin position="445"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="606" mass="68059" checksum="E71A9E2C36036612" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY04</accession>
    <name>G4MY04_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_10439</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EHA53532.1"/>
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    <dbReference type="GeneID" id="2682072"/>
    <dbReference type="KEGG" id="mgr:MGG_10439"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10439"/>
    <dbReference type="eggNOG" id="KOG2533">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="InParanoid" id="G4MY04"/>
    <dbReference type="OMA" id="FKHPTTY"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000188">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF50">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="73"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA53532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="522" mass="57571" checksum="27072AFF5AA80A88" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYS2</accession>
    <name>G4MYS2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">magnesium chelatase</fullName>
            <ecNumber evidence="1">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715108.1">
        <property type="nucleotide sequence ID" value="XM_003715060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYS2"/>
    <dbReference type="SMR" id="G4MYS2"/>
    <dbReference type="GeneID" id="2678360"/>
    <dbReference type="KEGG" id="mgr:MGG_08145"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08145"/>
    <dbReference type="eggNOG" id="ENOG502QQMN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034390_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYS2"/>
    <dbReference type="OMA" id="HWHDPED"/>
    <dbReference type="OrthoDB" id="5582146at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052041">
        <property type="entry name" value="Nucleic_acid_metab_PIN/TRAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11603">
        <property type="entry name" value="AAA FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11603:SF132">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ChlI/MoxR AAA lid" evidence="3">
        <location>
            <begin position="279"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA55301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="374" mass="40378" checksum="FA7A83ED82549C26" modified="2011-12-14" version="1">MADDDLLDKVHNLSDIELAVLLCLISREHCLISTPSEALNDLVGELHLIATRTFGLTCVTVDCHANTTLEDFATSLLLPTPSSPYVRPGSTSPLQTRGNDSYFQSQSVATPPLIRGGGLQPPRSPLISSSSSGACNATGTSTTALPGPGAIANVVLARNLDHAPSAVQAQALELLRTRRIFTRTTVQTAPRPFLLVAVVGADSGGQARVNPHLNDLLYMAHWHDPEDGFVNLEEMRAAEDIATEPVFSDADVSTLAKATQDVQFDIEVVRYQMNIVSFLRIHRAVDGGITPTATKHFERLIKCLAPLHRLDFVTPSLVAMAAKKVYLHRIKMVKAQAERSMQWGSDLAAVKAVLEDIGPEDVIEDVIAMVTPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N048</accession>
    <name>G4N048_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">O-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_05326</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Sterol O-acyltransferase that catalyzes the formation of stery esters.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712890.1">
        <property type="nucleotide sequence ID" value="XM_003712842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N048"/>
    <dbReference type="SMR" id="G4N048"/>
    <dbReference type="STRING" id="242507.G4N048"/>
    <dbReference type="GeneID" id="2675528"/>
    <dbReference type="KEGG" id="mgr:MGG_05326"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05326"/>
    <dbReference type="eggNOG" id="KOG0380">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018190_3_0_1"/>
    <dbReference type="InParanoid" id="G4N048"/>
    <dbReference type="OMA" id="RCHDYRR"/>
    <dbReference type="OrthoDB" id="10039049at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF7">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000439">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="507"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000439-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA53083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="554" mass="61986" checksum="670EE17FABCEF688" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0P5</accession>
    <name>G4N0P5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711285.1">
        <property type="nucleotide sequence ID" value="XM_003711237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0P5"/>
    <dbReference type="GeneID" id="12987008"/>
    <dbReference type="KEGG" id="mgr:MGG_16618"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16618"/>
    <dbReference type="HOGENOM" id="CLU_3087710_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0P5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="52" mass="5661" checksum="0B29C8F28C543558" modified="2011-12-14" version="1">MMLRPAVSCLSLTWTAFSDSTSRESPGRQVPKVPKCADMDSPSSFVNSKVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0Q0</accession>
    <name>G4N0Q0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NACHT and TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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            <taxon>Pyricularia</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_07408"/>
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        <property type="entry name" value="Goodbye_dom"/>
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        <property type="entry name" value="NPHP3-like_N"/>
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        <property type="entry name" value="TPR_rpt"/>
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    <dbReference type="PANTHER" id="PTHR10039">
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        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR10039:SF17">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN-RELATED"/>
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    <dbReference type="Pfam" id="PF17109">
        <property type="entry name" value="Goodbye"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="3"/>
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    </evidence>
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        <source>
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                <person name="Ebbole D.J."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
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                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    <accession>G4N0S2</accession>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <dbReference type="PubMed" id="15846337"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="136" mass="14821" checksum="A4BEABA6AEBC65E8" modified="2011-12-14" version="1">MAGLSAACLVFPYELAEATPESFVTRPLHNAIVKPDSIIASSELHVNFKVSIHLWANPAKQNARQSPKDQSALGKSDEMICFFGNQIFKVLGAFVKDGEYNSRIGQALEAHTLKDKVFSTHLTTDIAAGYRNPDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0Z8</accession>
    <name>G4N0Z8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin heavy chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07768</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasmic vesicle membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the clathrin heavy chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712981.1">
        <property type="nucleotide sequence ID" value="XM_003712933.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N0Z8"/>
    <dbReference type="FunCoup" id="G4N0Z8">
        <property type="interactions" value="1227"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N0Z8"/>
    <dbReference type="GeneID" id="2683695"/>
    <dbReference type="KEGG" id="mgr:MGG_07768"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07768"/>
    <dbReference type="eggNOG" id="KOG0985">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002136_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0Z8"/>
    <dbReference type="OMA" id="HCYDLLH"/>
    <dbReference type="OrthoDB" id="2113814at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071439">
        <property type="term" value="C:clathrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000001">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000002">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000005">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000082">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.730:FF:000003">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.110:FF:000003">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.110">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055358">
        <property type="entry name" value="CHCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016025">
        <property type="entry name" value="Clathrin_H-chain_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022365">
        <property type="entry name" value="Clathrin_H-chain_propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016341">
        <property type="entry name" value="Clathrin_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292:SF1">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00637">
        <property type="entry name" value="Clathrin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13838">
        <property type="entry name" value="Clathrin_H_link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01394">
        <property type="entry name" value="Clathrin_propel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002290">
        <property type="entry name" value="Clathrin_H_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50989">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="541"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="693"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="841"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="987"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1136"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1282"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1431"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1652"/>
            <end position="1680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA53174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1680" mass="189389" checksum="692CFD8EAE09991E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1H0</accession>
    <name>G4N1H0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713044.1">
        <property type="nucleotide sequence ID" value="XM_003712996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1H0"/>
    <dbReference type="GeneID" id="12985954"/>
    <dbReference type="KEGG" id="mgr:MGG_16939"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16939"/>
    <dbReference type="HOGENOM" id="CLU_1896642_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1H0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466452" evidence="1">
        <location>
            <begin position="23"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="134" mass="14787" checksum="89B2C35248DBBAD2" modified="2011-12-14" version="1">MYFATAFAIAAVLAFGPDNVIASRRMCILTLAEKTQNPEKPNFLEDTYQEVEAPAAAMLSYGGHEIHFELDKNCWPRLRHGSAVPPGYSAHIYSEGSDKYPPTSAVIEGTHVQKLPGFNPKGNVRFYEKLIGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1N7</accession>
    <name>G4N1N7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH-ubiquinone oxidoreductase 21.3 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711416.1">
        <property type="nucleotide sequence ID" value="XM_003711368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1N7"/>
    <dbReference type="SMR" id="G4N1N7"/>
    <dbReference type="STRING" id="242507.G4N1N7"/>
    <dbReference type="GeneID" id="2683424"/>
    <dbReference type="KEGG" id="mgr:MGG_07504"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07504"/>
    <dbReference type="eggNOG" id="ENOG502S2AU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081626_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1N7"/>
    <dbReference type="OMA" id="HPYEINE"/>
    <dbReference type="OrthoDB" id="2093493at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd22849">
        <property type="entry name" value="NuzM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016813">
        <property type="entry name" value="NADH_Ub_cplx-1_21kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022976">
        <property type="entry name" value="NADH_Oxi_21kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="20441" checksum="F34A1797F7236AA1" modified="2011-12-14" version="1">MASQAAAKAAGGVMNIATKQTLQSTGIWEKLRKSLSIDPNRSNGVPLNPHFRYPAPGSNDPMTYDDPVTLPAGDIADNPYWKRDHRRNYPALSVVKQADAVALLTVGNAAAPKAELIGEAGEKALVQAKEAGNSGLAAFFEKNGKSAALDVFVGGLPPTPAGESLVSGKWDVHKYEVSEQSYSEEYPARSFK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2020-06-17" modified="2025-02-05" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1S3</accession>
    <name>RAS1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Ras-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">RAS1</name>
        <name type="ORF">MGG_09499</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2006" name="Plant Cell" volume="18" first="2822" last="2835">
            <title>Multiple upstream signals converge on the adaptor protein Mst50 in Magnaporthe grisea.</title>
            <authorList>
                <person name="Park G."/>
                <person name="Xue C."/>
                <person name="Zhao X."/>
                <person name="Kim Y."/>
                <person name="Orbach M."/>
                <person name="Xu J.R."/>
            </authorList>
            <dbReference type="PubMed" id="17056708"/>
            <dbReference type="DOI" id="10.1105/tpc.105.038422"/>
        </citation>
        <scope>INTERACTION WITH MST50</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2014" name="Mol. Plant Microbe Interact." volume="27" first="996" last="1004">
            <title>Bypassing both surface attachment and surface recognition requirements for appressorium formation by overactive ras signaling in Magnaporthe oryzae.</title>
            <authorList>
                <person name="Zhou X."/>
                <person name="Zhao X."/>
                <person name="Xue C."/>
                <person name="Dai Y."/>
                <person name="Xu J.R."/>
            </authorList>
            <dbReference type="PubMed" id="24835254"/>
            <dbReference type="DOI" id="10.1094/mpmi-02-14-0052-r"/>
        </citation>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2019" name="Mol. Plant Pathol." volume="20" first="1264" last="1278">
            <title>The farnesyltransferase beta-subunit RAM1 regulates localization of RAS proteins and appressorium-mediated infection in Magnaporthe oryzae.</title>
            <authorList>
                <person name="Aboelfotoh Hendy A."/>
                <person name="Xing J."/>
                <person name="Chen X."/>
                <person name="Chen X.L."/>
            </authorList>
            <dbReference type="PubMed" id="31250536"/>
            <dbReference type="DOI" id="10.1111/mpp.12838"/>
        </citation>
        <scope>SUBCELLULAR LOCATION</scope>
        <scope>INTERACTION WITH RAM1</scope>
        <scope>MUTAGENESIS OF CYS-238</scope>
        <scope>ISOPRENYLATION AT CYS-238</scope>
    </reference>
    <comment type="function">
        <text evidence="1 3">Modulates the activity of the adenylate cyclase catalytic subunit and therefore affects the biosynthesis of cyclic-AMP (By similarity). Plays a role in both surface attachment and surface recognition of appressoria, a highly specialized infection structure for plant penetration. Regulates appressorium formation by coordinated regulation of cAMP signaling and Pmk1 MAPK pathways.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="3">Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with farnesyltransferase beta subunit RAM1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Lipid-anchor</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="6">Displays slight reduction in conidiation, but normal growth, appressorium formation, and plant infection.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712245.1">
        <property type="nucleotide sequence ID" value="XM_003712197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1S3"/>
    <dbReference type="SMR" id="G4N1S3"/>
    <dbReference type="STRING" id="242507.G4N1S3"/>
    <dbReference type="EnsemblFungi" id="MGG_09499T0">
        <property type="protein sequence ID" value="MGG_09499T0"/>
        <property type="gene ID" value="MGG_09499"/>
    </dbReference>
    <dbReference type="GeneID" id="2680536"/>
    <dbReference type="KEGG" id="mgr:MGG_09499"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09499"/>
    <dbReference type="eggNOG" id="KOG0395">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_9_8_1"/>
    <dbReference type="InParanoid" id="G4N1S3"/>
    <dbReference type="OMA" id="MWGCPFV"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000654">
        <property type="entry name" value="Small g-protein ras2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0449">Lipoprotein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0636">Prenylation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000449939" description="Ras-like protein 1">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="propeptide" id="PRO_0000449940" description="Removed in mature form" evidence="3">
        <location>
            <begin position="239"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="190"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Effector region" evidence="3">
        <location>
            <begin position="36"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="17"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="33"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="63"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="168"/>
            <end position="170"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Cysteine methyl ester" evidence="3">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="S-farnesyl cysteine" evidence="11">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Prevents farnesylation and restricts subcellular location to the cytoplasm in appressorium, mycelium, conidium and infection hyphae." evidence="7">
        <original>C</original>
        <variation>S</variation>
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="G4MZY8"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="P01112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="3">
        <source>
            <dbReference type="UniProtKB" id="P01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="15846337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="6">
        <source>
            <dbReference type="PubMed" id="24835254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="7">
        <source>
            <dbReference type="PubMed" id="31250536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="8">
        <source>
            <dbReference type="PubMed" id="17056708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="9">
        <source>
            <dbReference type="PubMed" id="24835254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="10"/>
    <evidence type="ECO:0000305" key="11">
        <source>
            <dbReference type="PubMed" id="31250536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA52438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="241" mass="26892" checksum="34EDB88C26BFF0E8" modified="2011-12-14" version="1" precursor="true">MTGRLQLHKLVVLGDGGVGKTALTIQLCLQHFVETYDPTIEDSYRKQVVIDNQACMLEVLDTAGQEEYTALRDQWIRDGEGFVLVYSISSRSSFSRIKRFHHQIQRVKESCASSPSYPGSPIATVTTQAPVPIMLVGNKSDRVTEREVSTQEGHALARELGCEFVEASAKNCINVEKAFYDVVRILRRQRQQASRPSLPGNSRTKTGGMGKSESFYQSDGKRGSRKDGEKHRSKPIKCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1X1</accession>
    <name>G4N1X1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_07852</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713088.1">
        <property type="nucleotide sequence ID" value="XM_003713040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1X1"/>
    <dbReference type="SMR" id="G4N1X1"/>
    <dbReference type="STRING" id="242507.G4N1X1"/>
    <dbReference type="GeneID" id="2683779"/>
    <dbReference type="KEGG" id="mgr:MGG_07852"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07852"/>
    <dbReference type="eggNOG" id="KOG3386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079690_0_2_1"/>
    <dbReference type="InParanoid" id="G4N1X1"/>
    <dbReference type="OMA" id="IDETTVC"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF79">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA53281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="174" mass="18964" checksum="8C6159EA7D1F12F9" modified="2011-12-14" version="1">MSHGHAAGPGAEDCQISMLWNWNTVGACFLSETWFVRTEGKMVVSCVGAMLLTATLELCRRGGREFDNLLASQIRQSVLSTALDTSSRRVETMRASLLQQFLRALLHAITFAIAYIVMLLAMYFNGYILVSIFLGAGLGKFLTDWLVVQVVVGEDGNSDCRGAIGVQETTVCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1Y6</accession>
    <name>G4N1Y6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713103.1">
        <property type="nucleotide sequence ID" value="XM_003713055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1Y6"/>
    <dbReference type="GeneID" id="2683793"/>
    <dbReference type="KEGG" id="mgr:MGG_07866"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07866"/>
    <dbReference type="eggNOG" id="ENOG502RN6R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_937034_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1Y6"/>
    <dbReference type="OrthoDB" id="3777014at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465641" evidence="2">
        <location>
            <begin position="23"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="340" mass="35070" checksum="C9638C9FF88FA882" modified="2011-12-14" version="1">MQMKHAFSSLLLAWLATAPVAAARSDRRLAARTLGNVTPSLVVDAIPVVDSNPLKKRVTSTSGGATRPQSNAAARPPANAAARPPANAALSPANNAALRPPTNAVVKPPTNAALKPPTNAALKPPTNAALKPPANAALKPPANAAPLPLGTSQRPPSGGGIRPAANAAPVSPAKTPVVPRPKSNPVCPTRRNMLGKRATTPVEAGTLAQGQAADELRTWSLKNCIGLAAADCTTGNKIMAHINGINEQQQDYKAQTIAFASHAALVDDKVTMRKPVAADFKNDLTATACAKVAGMVIDIKLLLQQYGFTVIEVERTLKDGDMQITAAGAINVDTGIRSVN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-02-13" modified="2025-02-05" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N285</accession>
    <name>OXR1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-linked oxidoreductase OXR1</fullName>
            <ecNumber evidence="5">1.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Pyriculol/pyriculariol biosynthesis cluster protein OXR1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">OXR1</name>
        <name type="ORF">MGG_10961</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2017" name="Microbiology" volume="163" first="541" last="553">
            <title>Unravelling the biosynthesis of pyriculol in the rice blast fungus Magnaporthe oryzae.</title>
            <authorList>
                <person name="Jacob S."/>
                <person name="Groetsch T."/>
                <person name="Foster A.J."/>
                <person name="Schueffler A."/>
                <person name="Rieger P.H."/>
                <person name="Sandjo L.P."/>
                <person name="Liermann J.C."/>
                <person name="Opatz T."/>
                <person name="Thines E."/>
            </authorList>
            <dbReference type="PubMed" id="27902426"/>
            <dbReference type="DOI" id="10.1099/mic.0.000396"/>
        </citation>
        <scope>IDENTIFICATION</scope>
        <scope>INDUCTION</scope>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>PATHWAY</scope>
    </reference>
    <comment type="function">
        <text evidence="5 8">FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of pyriculol and pyriculariol, two heptaketides that induce lesion formation upon application on rice leaves but are dispensable for pathogenicity (PubMed:27902426). The highly reducing polyketide synthase synthesizes the heptaketide backbone of pyriculol and pyriculariol (PubMed:27902426). Pyriculol and pyriculariol contain several hydroxyl moieties and double bonds, so it can be assumed that several reduction steps occur during biosynthesis. These reactions could be executed by PKS19 itself or partly by the tailoring enzymes OXR1, OXR2, RED1, RED2 or RED3, identified within the cluster (Probable). The FAD-linked oxidoreductase OXR1 is the only tailoring enzyme for which the function has been determined yet, and is involved in the oxidation of dihydropyriculol and dihydropyriculariol into pyriculol and pyriculariol, respectively (PubMed:27902426).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dihydropyriculol + A = pyriculol + AH2</text>
            <dbReference type="Rhea" id="RHEA:63972"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:80728"/>
            <dbReference type="ChEBI" id="CHEBI:142635"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:63973"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dihydropyriculariol + A = pyriculariol + AH2</text>
            <dbReference type="Rhea" id="RHEA:63976"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:142636"/>
            <dbReference type="ChEBI" id="CHEBI:142637"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:63977"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyketide biosynthesis.</text>
    </comment>
    <comment type="induction">
        <text evidence="5">Expression is increased in rice-extract medium (REM) and is correlated with the production of pyriculol.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="5">Impairs the production of pyriculol and pyriculariol, but accumulates their reduced forms dihydropyriculol and dihydropyriculariol.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712304.1">
        <property type="nucleotide sequence ID" value="XM_003712256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N285"/>
    <dbReference type="SMR" id="G4N285"/>
    <dbReference type="STRING" id="242507.G4N285"/>
    <dbReference type="GlyCosmos" id="G4N285">
        <property type="glycosylation" value="4 sites, No reported glycans"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_10961T0">
        <property type="protein sequence ID" value="MGG_10961T0"/>
        <property type="gene ID" value="MGG_10961"/>
    </dbReference>
    <dbReference type="GeneID" id="2677715"/>
    <dbReference type="KEGG" id="mgr:MGG_10961"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10961"/>
    <dbReference type="eggNOG" id="ENOG502SJ3M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_0_0_1"/>
    <dbReference type="InParanoid" id="G4N285"/>
    <dbReference type="OMA" id="MAKQHNI"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF9">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0274">FAD</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466490" description="FAD-linked oxidoreductase OXR1" evidence="2">
        <location>
            <begin position="22"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="73"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q5BEJ5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="27902426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="6">
        <source>
            <dbReference type="PubMed" id="27902426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="7"/>
    <evidence type="ECO:0000305" key="8">
        <source>
            <dbReference type="PubMed" id="27902426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA52497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="507" mass="54993" checksum="6B5587E53277A258" modified="2011-12-14" version="1" precursor="true">MTIKFASLILAGLGLGSGALGSVTFRREESSWTNDSLTSVFAQQAKGLFLPRTVISFQGQEWFENVTERWDIYAPPTFKVSVSPSTEKDVESAVKLAAKFKIPFLATGGRHGYGTTLGKLKNGLSIDLSLLNQFSIDSKAATITVGPGVRFRDIFTPLYEAGFQVPTGTCSCVGMIGATLGGGIGRLNGLDGLMIDALESARVVTADGRTLTVSEKENKDLFWGMRGAGQNFGVVVSATYKLKPLYAAGVWTNVDLIFSPDKNATYFDVVTSMEVPPQLTIASVVTYNATLDEPQLIATLTWTGPRDEALAAMKPILDVGPRHSEVTEATYATLPRVATFGTTDAVCAPGQIYDIYGVGLRRLDSAAWRSTFSKMARFYAAEPAGRASSILYETWPVQATVAVPDDATAYPWRDASTYVLIQMRWDRPGSPLERAADRLGAELRSDLSATGGYQGAGPAVYVNYAHGDERLEDIYGARKLPRLAKLKKQYDPGNVFRFHHALPTKYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3U3</accession>
    <name>G4N3U3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712523.1">
        <property type="nucleotide sequence ID" value="XM_003712475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3U3"/>
    <dbReference type="SMR" id="G4N3U3"/>
    <dbReference type="STRING" id="242507.G4N3U3"/>
    <dbReference type="GeneID" id="2675383"/>
    <dbReference type="KEGG" id="mgr:MGG_05017"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05017"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020129_1_0_1"/>
    <dbReference type="InParanoid" id="G4N3U3"/>
    <dbReference type="OMA" id="ASYGLWG"/>
    <dbReference type="OrthoDB" id="5423360at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="178"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="631" mass="69320" checksum="0BA3A4E7A4FD2495" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4L7</accession>
    <name>G4N4L7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_05994"/>
    <dbReference type="eggNOG" id="ENOG502RWXH">
        <property type="taxonomic scope" value="Eukaryota"/>
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            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <source>
            <strain>70-15</strain>
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    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
    <sequence length="82" mass="8727" checksum="C45E9FAB242DB2CF" modified="2011-12-14" version="1">MSRLSDKGRRNSFARPASGGYIVRGMVGLISAADGRAAETCLFRGHVIGSGTLIHKSTVLEPISLDVYVTGVIRNQNQHAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4X5</accession>
    <name>G4N4X5_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">Histone deacetylase HOS3</fullName>
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        <name evidence="3" type="ORF">MGG_06043</name>
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    <organism evidence="3 4">
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Sordariomycetidae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA52087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_06043"/>
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        <property type="entry name" value="Hist_deacetyl"/>
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            <end position="574"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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    <feature type="region of interest" description="Disordered" evidence="1">
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    <feature type="region of interest" description="Disordered" evidence="1">
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="654"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="790"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="860"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="900"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="934"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1141" mass="123630" checksum="3A69AF5F2A515189" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4X7</accession>
    <name>G4N4X7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06045</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711896.1">
        <property type="nucleotide sequence ID" value="XM_003711848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4X7"/>
    <dbReference type="FunCoup" id="G4N4X7">
        <property type="interactions" value="311"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N4X7"/>
    <dbReference type="GeneID" id="2683930"/>
    <dbReference type="KEGG" id="mgr:MGG_06045"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06045"/>
    <dbReference type="eggNOG" id="KOG3114">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059606_2_1_1"/>
    <dbReference type="InParanoid" id="G4N4X7"/>
    <dbReference type="OMA" id="VFRRCVA"/>
    <dbReference type="OrthoDB" id="10256463at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039765">
        <property type="entry name" value="Yip5/YIPF1/YIPF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="7">
        <location>
            <begin position="95"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="281" mass="30533" checksum="690339CC3C39C10E" modified="2011-12-14" version="1">MSGPGYDAVVDIDDEGDLGHTDLQDDLEFHNSTFSETTPGARKPGAVGGAGSSGLPLPATASTVSGKRYLWTVSYYAQFFDVDTSAVLSRCWAALYPRANFLDVLEGNPDLYGPFWIATTVIFILFIGGTISQYLATRGTTEAFVYDFTLLSGAAGLIYGYTLFLPVVLFLALRYFGSESANLLECWALYGYANLIWIPVALISWSQIDILNFVFVAVGFGYSVAFLLRNLYPVLSATDRQTSKILLIVVVALHFALAVTIKILFFAHHSPVAKGDGKAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4N534</accession>
    <name>G4N534_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein phosphatase 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_05207</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712752.1">
        <property type="nucleotide sequence ID" value="XM_003712704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N534"/>
    <dbReference type="SMR" id="G4N534"/>
    <dbReference type="FunCoup" id="G4N534">
        <property type="interactions" value="252"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N534"/>
    <dbReference type="GeneID" id="2675671"/>
    <dbReference type="KEGG" id="mgr:MGG_05207"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05207"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013173_9_1_1"/>
    <dbReference type="InParanoid" id="G4N534"/>
    <dbReference type="OMA" id="METDNGY"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="PHI-base" id="PHI:123077"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000078">
        <property type="entry name" value="Protein phosphatase 2C, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF837">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="7">
        <location>
            <begin position="151"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="489"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="561" mass="58728" checksum="4AC70695A3ABAA7D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N544</accession>
    <name>G4N544_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 71A23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712762.1">
        <property type="nucleotide sequence ID" value="XM_003712714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N544"/>
    <dbReference type="STRING" id="242507.G4N544"/>
    <dbReference type="GeneID" id="2675619"/>
    <dbReference type="KEGG" id="mgr:MGG_05215"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05215"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="InParanoid" id="G4N544"/>
    <dbReference type="OMA" id="MPQYDEV"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000113">
        <property type="entry name" value="Cytochrome P450 monooxygenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF85">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="509" mass="57790" checksum="1E963FF7B34B2684" modified="2011-12-14" version="1">MAILSPVGLVLIPLAYIVYKILQQIAKYRLNHPLNPFPGPWLASVTRLWITYHNVKADECQTFRELHRRHGPVVRITPTMLHVSDAVKLPEIYSRNADKSQHYITGSFGTTESLFNMQDHKVHAHFRKIAASPYSFSNVKRMEPLLDSNIDRWIHRLDEQFASTRQRFDFAPWAVYMAYDIISEVGFGQPFGFIEQGRDVEGLIKGFHDGLVPFGIMARLWPFTNWVKTTFLGRYLVASPEQDSGIGTLMRLRDRLITQRIADNEKSGGNSHARVDLLQTFLEARDDEGRPLDVAHVKAEILLVLLAGADTTGTTFQAIVMHVASRPDVYERMMAEVDAAAAAGKLSSPTPRHEEVQAHCPYYVACVRETMRLNPAAPNIFPRLAPAGGIDLYGVRVPGGTELTCNPWIVHRDPAVVGDDPDHFRPERWLEDGDRAKAMLRYSMSFGYGARECLGKHIAMELFKAPIRFFQTFKPDILDKTNPGRYVVKGGVSYFEDMWIKIERRVRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5I7</accession>
    <name>G4N5I7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711986.1">
        <property type="nucleotide sequence ID" value="XM_003711938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5I7"/>
    <dbReference type="STRING" id="242507.G4N5I7"/>
    <dbReference type="GeneID" id="2684278"/>
    <dbReference type="KEGG" id="mgr:MGG_06120"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06120"/>
    <dbReference type="eggNOG" id="ENOG502S6UJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012849_2_1_1"/>
    <dbReference type="InParanoid" id="G4N5I7"/>
    <dbReference type="OMA" id="CCHALDE"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000500">
        <property type="term" value="C:RNA polymerase I upstream activating factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000182">
        <property type="term" value="F:rDNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001181">
        <property type="term" value="F:RNA polymerase I general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039601">
        <property type="entry name" value="Rrn5"/>
    </dbReference>
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        <property type="entry name" value="SANT/Myb"/>
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        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN5"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN5"/>
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        <property type="entry name" value="Homeodomain-like"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="638" mass="71390" checksum="98692B45A63CBAA0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5V5</accession>
    <name>G4N5V5_PYRO7</name>
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        <submittedName>
            <fullName evidence="4">Pyoverdine/dityrosine biosynthesis family protein</fullName>
        </submittedName>
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        <name evidence="4" type="ORF">MGG_08540</name>
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    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716050.1">
        <property type="nucleotide sequence ID" value="XM_003716002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5V5"/>
    <dbReference type="SMR" id="G4N5V5"/>
    <dbReference type="STRING" id="242507.G4N5V5"/>
    <dbReference type="GeneID" id="2678837"/>
    <dbReference type="KEGG" id="mgr:MGG_08540"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08540"/>
    <dbReference type="eggNOG" id="ENOG502RUDQ">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_015940_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5V5"/>
    <dbReference type="OMA" id="WAYGETL"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Isocyanide_synthase_DIT1"/>
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        <property type="entry name" value="TauD/TfdA-like"/>
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    <dbReference type="PANTHER" id="PTHR37285">
        <property type="entry name" value="SPORE WALL MATURATION PROTEIN DIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37285:SF5">
        <property type="entry name" value="SPORE WALL MATURATION PROTEIN DIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DIT1_PvcA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="412"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="671" mass="74245" checksum="7D8815ED3564570D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5Y0</accession>
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        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_03124</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        </lineage>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003716827.1"/>
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    <dbReference type="FunCoup" id="G4N5Y0">
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    <dbReference type="GeneID" id="2676921"/>
    <dbReference type="KEGG" id="mgr:MGG_03124"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03124"/>
    <dbReference type="eggNOG" id="KOG0255">
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    <dbReference type="HOGENOM" id="CLU_008455_13_0_1"/>
    <dbReference type="InParanoid" id="G4N5Y0"/>
    <dbReference type="OMA" id="LVQCTIG"/>
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    <dbReference type="Proteomes" id="UP000009058">
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    <dbReference type="GO" id="GO:0005886">
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
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    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
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    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF20">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="432"/>
            <end position="458"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="470"/>
            <end position="490"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="496"/>
            <end position="519"/>
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        <location>
            <begin position="72"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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        <property type="protein sequence ID" value="EHA50597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_06612"/>
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    <dbReference type="OrthoDB" id="5377599at2759"/>
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        <property type="entry name" value="KEY LIME PATHOGENICITY PROTEIN"/>
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    <dbReference type="PANTHER" id="PTHR42031:SF1">
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            <end position="602"/>
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        </location>
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    </evidence>
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    </evidence>
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    <accession>G4N6E7</accession>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003716088.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_13467"/>
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    <dbReference type="InParanoid" id="G4N6E7"/>
    <dbReference type="OMA" id="PEAIDSC"/>
    <dbReference type="OrthoDB" id="1938992at2759"/>
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    <dbReference type="GO" id="GO:0033255">
        <property type="term" value="C:SAS acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Sas4_dom"/>
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        <property type="entry name" value="SAS4"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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    </feature>
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    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="473"/>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF15460"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49817.1"/>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6I2</accession>
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        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716171.1">
        <property type="nucleotide sequence ID" value="XM_003716123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6I2"/>
    <dbReference type="STRING" id="242507.G4N6I2"/>
    <dbReference type="GeneID" id="2676783"/>
    <dbReference type="KEGG" id="mgr:MGG_03710"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03710"/>
    <dbReference type="eggNOG" id="ENOG502RYMZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005679_13_0_1"/>
    <dbReference type="InParanoid" id="G4N6I2"/>
    <dbReference type="OMA" id="QITWPWA"/>
    <dbReference type="OrthoDB" id="5819582at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF126">
        <property type="entry name" value="ACYLTRANSFERASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="43"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="490" mass="56102" checksum="EB96FFADC07C09F8" modified="2011-12-14" version="1">MARYDNQAIRLPGRVFRALLPSFIADLLYPDLKPAYRLHTTSYLDGLRGIASFIVFFCHYTEENHKYMIPSYGLNPKGQVSSWLQLPFLRIVFSGRPMVHIFFIISGFVLSNKPLKLLHAKDLEKSAAAVASSAFRRPFRLYGPCIVSTFIIALLIQMGYLYEPKETLAEQLWNWKDAVFHSVTWPWAWDHDLRPGYDVHLWTIPIEMAHSMLLFLVLITLSLVRLRLRQFINFALMIYCLCCGKWAGFEFLGGMFLAEIRLLQASGNGEWWGELQKRHRILPIMRSAFWCGVIIVFVFVGGWPNFDADKTPGIRYLNAHTPYPFATMDALAPQKYWFAIAAIFALYACGELVWVRRFLDSAVGQYCGRLSYAIYIIHGPVLEMFQKMTIGQPFAPQKGNPGEKGFVPAQLGKGIKGMIGVEGPTQRFACWATGLLILFPIVVWVSDIFWRLVDAPIVELARKVEKLCVDEEIQPNNRREHGQRYQMVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6I3</accession>
    <name>G4N6I3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716172.1">
        <property type="nucleotide sequence ID" value="XM_003716124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6I3"/>
    <dbReference type="SMR" id="G4N6I3"/>
    <dbReference type="STRING" id="242507.G4N6I3"/>
    <dbReference type="GeneID" id="2676782"/>
    <dbReference type="KEGG" id="mgr:MGG_03709"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03709"/>
    <dbReference type="eggNOG" id="KOG0718">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019611_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6I3"/>
    <dbReference type="OMA" id="IWYTYHG"/>
    <dbReference type="OrthoDB" id="666364at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="106"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="820" mass="89281" checksum="011905F63AA38FC1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N716</accession>
    <name>G4N716_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Elongation factor 1-alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_03641</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716248.1">
        <property type="nucleotide sequence ID" value="XM_003716200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N716"/>
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        <property type="entry name" value="EF-1_alpha"/>
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        <property type="entry name" value="ELONGATNFCT"/>
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        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
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    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="10 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="6"/>
            <end position="254"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
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            <dbReference type="ARBA" id="ARBA00023134"/>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000325"/>
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    </evidence>
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            <dbReference type="PROSITE" id="PS51722"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA49929.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="473" mass="51290" checksum="98BC718245E44D81" modified="2011-12-14" version="1">MGNKEKSHLNVVVIGHVDSGKSTTTGHLIYKLKGIDQRTIEKYEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETAKYQVTVIDAPGHRDFIKNMITGTSQADCAILVIGAGTGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDTAKWAQSRYDEIVKETSNFLKKIGFNPDSVPFVPISGFNGDHMISESADIKGNISPNAPWYKGWTKTVNKDGKKEKVIGGASLQDAIDDVTPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRIETGILKPGMVVTFAPANVTTEVKSVEMHHQQLPEGVPGDNVGFNVKNVSVKDIRRGNVAGDSKNDPPMGCASFNAQVIILNHPGQVGAGYAPVLDCHTAHIACKFSEILEKLDRRTGKSIESNPKFIKSGDAAIVKMIPSKPMCVETFSEYPPLGRFAVRDMRQTVAVGVIKSVDKSQGTQGKVTKSAAKAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7R5</accession>
    <name>G4N7R5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03529</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716389.1">
        <property type="nucleotide sequence ID" value="XM_003716341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7R5"/>
    <dbReference type="FunCoup" id="G4N7R5">
        <property type="interactions" value="18"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7R5"/>
    <dbReference type="GeneID" id="2676907"/>
    <dbReference type="KEGG" id="mgr:MGG_03529"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03529"/>
    <dbReference type="eggNOG" id="ENOG502QW3E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012543_1_0_1"/>
    <dbReference type="InParanoid" id="G4N7R5"/>
    <dbReference type="OMA" id="NKGWAWN"/>
    <dbReference type="OrthoDB" id="4005299at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018825">
        <property type="entry name" value="DUF2427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018827">
        <property type="entry name" value="YTP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_6G12730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_6G12730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10348">
        <property type="entry name" value="DUF2427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10355">
        <property type="entry name" value="Ytp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466680" evidence="3">
        <location>
            <begin position="25"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="518"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="556"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2427" evidence="4">
        <location>
            <begin position="46"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Protein YTP1-like C-terminal" evidence="5">
        <location>
            <begin position="294"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="596" mass="64710" checksum="829608D4D7CC62B7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7S3</accession>
    <name>G4N7S3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">54S ribosomal protein L12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_06378</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717196.1">
        <property type="nucleotide sequence ID" value="XM_003717148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7S3"/>
    <dbReference type="SMR" id="G4N7S3"/>
    <dbReference type="FunCoup" id="G4N7S3">
        <property type="interactions" value="737"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7S3"/>
    <dbReference type="GeneID" id="2684533"/>
    <dbReference type="KEGG" id="mgr:MGG_06378"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06378"/>
    <dbReference type="eggNOG" id="KOG1715">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086499_0_1_1"/>
    <dbReference type="InParanoid" id="G4N7S3"/>
    <dbReference type="OMA" id="LEDKWGV"/>
    <dbReference type="OrthoDB" id="250175at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L7/L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_bL12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 oligomerization" evidence="5">
        <location>
            <begin position="45"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="4">
        <location>
            <begin position="110"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="177" mass="18577" checksum="6D615C85158A4977" modified="2011-12-14" version="1">MSVSCRYAAQCCSRQLRVSPSVRVSGVAVQRIARRHNSTEAASPKITTIVDQISQLTLLETAELVSSLKSRLNIPDLPVGGFAAAAPAAAPAAAEEADEPAPAAAAKTVFTLKLMSFDAGAKAKIIKEVKGLLGLSLVDSKKFVESAPKVMKESVPKEDAEKIIATMKELGAVVTME</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7U7</accession>
    <name>G4N7U7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amylase-binding protein AbpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_06358</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717220.1">
        <property type="nucleotide sequence ID" value="XM_003717172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7U7"/>
    <dbReference type="SMR" id="G4N7U7"/>
    <dbReference type="FunCoup" id="G4N7U7">
        <property type="interactions" value="547"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7U7"/>
    <dbReference type="GeneID" id="2684513"/>
    <dbReference type="KEGG" id="mgr:MGG_06358"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06358"/>
    <dbReference type="eggNOG" id="KOG3655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013085_2_0_1"/>
    <dbReference type="InParanoid" id="G4N7U7"/>
    <dbReference type="OMA" id="FKEPRGA"/>
    <dbReference type="OrthoDB" id="5971719at2759"/>
    <dbReference type="PHI-base" id="PHI:8629"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11281">
        <property type="entry name" value="ADF_drebrin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11962">
        <property type="entry name" value="SH3_Abp1_fungi_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11961">
        <property type="entry name" value="SH3_Abp1_fungi_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000242">
        <property type="entry name" value="Actin binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000273">
        <property type="entry name" value="Actin binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000045">
        <property type="entry name" value="Actin binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035719">
        <property type="entry name" value="Abp1_fungi_SH3_C1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035718">
        <property type="entry name" value="Abp1_fungi_SH3_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF25">
        <property type="entry name" value="DREBRIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="ADF-H" evidence="5">
        <location>
            <begin position="5"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="641"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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            <dbReference type="EMBL" id="EHA50901.1"/>
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        <source>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    </evidence>
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    </evidence>
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    </evidence>
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</entry>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="242507.G4N982"/>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
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    <dbReference type="KEGG" id="mgr:MGG_03315"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03315"/>
    <dbReference type="eggNOG" id="ENOG502SKA3">
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    <dbReference type="OMA" id="NEECKAS"/>
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    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="36251" checksum="8B0A4964A0F9976B" modified="2011-12-14" version="1">MASYKSFFMLLSAVTSASAQQYKLVKSYNRSTNFFDFFNVRDRAFFNNLGYATGDPTSGFVDYATRQEALSSGLMAYRGNQMYIGVDSTNTVPVNGRGRKSVRLESRETFNGGLLLADIAHMPGNACGVWPALWAYNMNENPISEIDFLEGNGWTGQAENTVSLHTCGRCAFPNLKGPELRRDCDLKGCEGTPSNPAGCGVNGGKGSFGTGFNNGGGGIYALLLDTTGIRVWFLPRNKITSDITSGKPNPSLWGTPQADFRSSSSCNVGKTFKDLTIIVNTSFCGAIMYDYKAQMEGYPQCGSAPGGSCNAYVGANPQAYKESYWLFNSIKIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9A5</accession>
    <name>G4N9A5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717465.1">
        <property type="nucleotide sequence ID" value="XM_003717417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9A5"/>
    <dbReference type="GeneID" id="12986543"/>
    <dbReference type="KEGG" id="mgr:MGG_17240"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17240"/>
    <dbReference type="HOGENOM" id="CLU_2483792_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9A5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045634">
        <property type="entry name" value="DUF6413"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19951">
        <property type="entry name" value="DUF6413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466726" evidence="1">
        <location>
            <begin position="18"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="87" mass="9143" checksum="DAC961F6EF746A02" modified="2011-12-14" version="1">MRSFSLCLSPLLQFLVGAPGPSKTCTGLKLNSYGCIDSPADDDFGGCDGITNWPIGRDVKAFEPGSVVSHTQAETFNIEVGFVGCAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9R7</accession>
    <name>G4N9R7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_10685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715893.1">
        <property type="nucleotide sequence ID" value="XM_003715845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9R7"/>
    <dbReference type="STRING" id="242507.G4N9R7"/>
    <dbReference type="GeneID" id="2682886"/>
    <dbReference type="KEGG" id="mgr:MGG_10685"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10685"/>
    <dbReference type="eggNOG" id="ENOG502TB5B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1001422_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9R7"/>
    <dbReference type="OMA" id="HHIMSAG"/>
    <dbReference type="OrthoDB" id="4509729at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="278" mass="30570" checksum="10111A8D4564092F" modified="2011-12-14" version="1">MGTTSVFSPAAQFGQRRTQSAKTSPNRTKSHLSAATQQQQQQQQQTTVTTTTPTQQPLTMLPLDARPAPPTRIMSAAVAQQPQPGSNKTPQNITVTTTNLFQDDEEDADCSPHPHNLDLNLAKYRLLESQHEALLSHLDSLQLARRPSSQGSTGSSPPSFSSRRSSSASSYYRRRYHSSSARSSTVGGATSPVHHIMSAGPLETVPDGDEVCLFGEDERRLFDVNEAIKRSLTELLNCEQARADPGFRTQIQSRLMEAERELRTGRRRRSCASSVGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA29</accession>
    <name>G4NA29_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_09757</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glycosyl hydrolase 31 family.</text>
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    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717594.1">
        <property type="nucleotide sequence ID" value="XM_003717546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA29"/>
    <dbReference type="SMR" id="G4NA29"/>
    <dbReference type="STRING" id="242507.G4NA29"/>
    <dbReference type="CAZy" id="GH31">
        <property type="family name" value="Glycoside Hydrolase Family 31"/>
    </dbReference>
    <dbReference type="GeneID" id="2680756"/>
    <dbReference type="KEGG" id="mgr:MGG_09757"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09757"/>
    <dbReference type="eggNOG" id="KOG1066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_9_0_1"/>
    <dbReference type="InParanoid" id="G4NA29"/>
    <dbReference type="OMA" id="LPRGRWY"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF165">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="7">
        <location>
            <begin position="37"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="6">
        <location>
            <begin position="259"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="8">
        <location>
            <begin position="628"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA51275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="859" mass="95382" checksum="E2C934FCB80796C0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAK0</accession>
    <name>G4NAK0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Small ribosomal subunit protein mS37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the mitochondrial small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the mitochondrion-specific ribosomal protein mS37 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717657.1">
        <property type="nucleotide sequence ID" value="XM_003717609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAK0"/>
    <dbReference type="SMR" id="G4NAK0"/>
    <dbReference type="FunCoup" id="G4NAK0">
        <property type="interactions" value="77"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAK0"/>
    <dbReference type="GeneID" id="2680697"/>
    <dbReference type="KEGG" id="mgr:MGG_09698"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09698"/>
    <dbReference type="eggNOG" id="ENOG502SBQ7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162186_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAK0"/>
    <dbReference type="OMA" id="INYHAAR"/>
    <dbReference type="OrthoDB" id="2210at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017264">
        <property type="entry name" value="Ribosomal_mS37_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28066">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28066:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037706">
        <property type="entry name" value="MRP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR037706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="93" mass="10192" checksum="A85F82B856200A38" modified="2011-12-14" version="1">MSSVKKPMRLPPLKALRVRNPDVKEVNPCLAVMSSVLACWASAGYTAQGCAALEQSLRACMDGPPAPKPKKSEINYHLSRMYPKIVGPRKLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAV8</accession>
    <name>G4NAV8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pps1 dual specificty phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716869.1">
        <property type="nucleotide sequence ID" value="XM_003716821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAV8"/>
    <dbReference type="SMR" id="G4NAV8"/>
    <dbReference type="FunCoup" id="G4NAV8">
        <property type="interactions" value="6"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAV8"/>
    <dbReference type="GeneID" id="2676927"/>
    <dbReference type="KEGG" id="mgr:MGG_03130"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03130"/>
    <dbReference type="eggNOG" id="KOG1716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003560_1_0_1"/>
    <dbReference type="InParanoid" id="G4NAV8"/>
    <dbReference type="OMA" id="NKPYSRQ"/>
    <dbReference type="OrthoDB" id="273181at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033260">
        <property type="term" value="P:nuclear DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000110">
        <property type="entry name" value="PPS1p Protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053239">
        <property type="entry name" value="Dual_spec_PTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47550">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47550:SF1">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PPS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="522"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="590"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="44"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="699" mass="77694" checksum="A1F7C03C53481422" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBA6</accession>
    <name>G4NBA6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CIA30 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_00588</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CIA30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718452.1">
        <property type="nucleotide sequence ID" value="XM_003718404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBA6"/>
    <dbReference type="SMR" id="G4NBA6"/>
    <dbReference type="STRING" id="242507.G4NBA6"/>
    <dbReference type="GeneID" id="2675162"/>
    <dbReference type="KEGG" id="mgr:MGG_00588"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00588"/>
    <dbReference type="eggNOG" id="ENOG502S3C5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059028_3_1_1"/>
    <dbReference type="InParanoid" id="G4NBA6"/>
    <dbReference type="OMA" id="IMVRSFF"/>
    <dbReference type="OrthoDB" id="426386at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010257">
        <property type="term" value="P:NADH dehydrogenase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194:SF19">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466058" evidence="3">
        <location>
            <begin position="22"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="4">
        <location>
            <begin position="34"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA48868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="252" mass="27520" checksum="2FEC6BA4AEFE43FD" modified="2011-12-14" version="1">MRAALPAVLLLDWSFAMSIMAGNRYIFGGDKPWDEAGFTAVDDRVRGGSSVSHLIVNADRTAATFNGTLDTKTLGGAGFASQRTVDPFLVDLTGVGALIADVVVPADNKTYTLTLKNDILPTGPDGREQSTVSWEYDFVALGDGDKEGETKQVKMPIDQFKPTYRGRPAEDAKLDLANIKRISFMMRSFFEKQDGDFSLTIKSLAVSQSVQSESPARISEAISDDGDSKGQANQALSAEKEVPIWRRWLCNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBY2</accession>
    <name>G4NBY2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WKF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717768.1">
        <property type="nucleotide sequence ID" value="XM_003717720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBY2"/>
    <dbReference type="FunCoup" id="G4NBY2">
        <property type="interactions" value="176"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NBY2"/>
    <dbReference type="GeneID" id="2674962"/>
    <dbReference type="KEGG" id="mgr:MGG_01154"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01154"/>
    <dbReference type="eggNOG" id="KOG4829">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045013_1_0_1"/>
    <dbReference type="InParanoid" id="G4NBY2"/>
    <dbReference type="OMA" id="NAFRECL"/>
    <dbReference type="OrthoDB" id="10261563at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019327">
        <property type="entry name" value="WKF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22306">
        <property type="entry name" value="CHROMOSOME 7 OPEN READING FRAME 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22306:SF2">
        <property type="entry name" value="CHROMOSOME 7 OPEN READING FRAME 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10180">
        <property type="entry name" value="WKF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WKF" evidence="2">
        <location>
            <begin position="150"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="433" mass="46813" checksum="375CEBEFC993432D" modified="2011-12-14" version="1">MSFAKSMPAQRVPAWKRLGLKLKGSADNDNTSLLPPSQPAAVATSSPSSNISGYSSNNKRKDYPVSNGTADEASVSKRSRTDLDRPFQGRRKSVTFADGTKDSDPVTPAATETPSKPKPKKIKKKSKGSKTEKQPGQDFKPTQIQPELSKYLREWETSRENWKFKKNYQTLLIKYAFTPEMVPAADFGIFLKYSRDSKGASRDWLKKSAEDVRKKDLGLAAASTGDVAKEQEKYASLLATMLQSHPGSGTNANGKRVRDDYNEEDFVMGGTNAIDPRDPEVTQRLVKRLRAELVLDELSSGDDSEATTTTTGTSEAASTPRESTLASTSDAAVAGDVGAKDGRRKRNRNKRTLAEDDASSSSDSSDDEDADDADEDDDTSSSGTSSSGSEDSGSESEGTLLRLQQQREELDTSSESSSSSDSDSDSSSDGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBZ0</accession>
    <name>G4NBZ0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-reducing end alpha-L-arabinofuranosidase</fullName>
            <ecNumber evidence="4">3.2.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_01147</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.</text>
            <dbReference type="EC" id="3.2.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 51 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.55" evidence="4"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717776.1">
        <property type="nucleotide sequence ID" value="XM_003717728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBZ0"/>
    <dbReference type="SMR" id="G4NBZ0"/>
    <dbReference type="STRING" id="242507.G4NBZ0"/>
    <dbReference type="CAZy" id="GH51">
        <property type="family name" value="Glycoside Hydrolase Family 51"/>
    </dbReference>
    <dbReference type="GeneID" id="2674167"/>
    <dbReference type="KEGG" id="mgr:MGG_01147"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01147"/>
    <dbReference type="eggNOG" id="ENOG502QQEX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010060_1_1_1"/>
    <dbReference type="InParanoid" id="G4NBZ0"/>
    <dbReference type="OMA" id="NEGYWGM"/>
    <dbReference type="OrthoDB" id="406864at2759"/>
    <dbReference type="UniPathway" id="UPA00667"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046373">
        <property type="term" value="P:L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010720">
        <property type="entry name" value="Alpha-L-AF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055235">
        <property type="entry name" value="ASD1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051563">
        <property type="entry name" value="Glycosyl_Hydrolase_51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31776:SF0">
        <property type="entry name" value="ALPHA-L-ARABINOFURANOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06964">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22848">
        <property type="entry name" value="ASD1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00813">
        <property type="entry name" value="Alpha-L-AF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466039" description="non-reducing end alpha-L-arabinofuranosidase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-arabinofuranosidase C-terminal" evidence="9">
        <location>
            <begin position="471"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA48192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="667" mass="73635" checksum="2CDD4072D2BF98EF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC13</accession>
    <name>G4NC13_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutathione S-transferase UstS-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718600.1">
        <property type="nucleotide sequence ID" value="XM_003718552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC13"/>
    <dbReference type="SMR" id="G4NC13"/>
    <dbReference type="GeneID" id="2674153"/>
    <dbReference type="KEGG" id="mgr:MGG_11575"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11575"/>
    <dbReference type="eggNOG" id="ENOG502QQN3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_4_1_1"/>
    <dbReference type="InParanoid" id="G4NC13"/>
    <dbReference type="OMA" id="RAGVSCW"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione S-transferase UstS-like C-terminal" evidence="1">
        <location>
            <begin position="137"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="247" mass="27734" checksum="5FB1303EFD333C40" modified="2011-12-14" version="1">MEDQHEILFYDIASGPPVRPFAVNPCKTRYALNFKKVSYKTELVELPDVKNVRKSLECAPVRKHMDGSDFYTLPIVKNTKTGEIVGDSFDIALYLDRTFQTGPRLMAAGTEGLTAAFNAQVDALWVQIVRLGMRNFPFNPANGHIYKAEACARFGAESWEAMDTQTEEERVKILKDGEAALEPLAKWYRMDESGPFLAGAQVAYADIAVGGWLLMYSVTFPPEEFAQVMAWHGGVWGRLHEALAEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDC5</accession>
    <name>G4NDC5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose receptor Git3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00258</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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                <person name="Butler J."/>
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                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
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                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
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                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
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                <person name="Saif S."/>
                <person name="Shea T."/>
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                <person name="Stolte C."/>
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                <person name="Yandava C."/>
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                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
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                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718173.1">
        <property type="nucleotide sequence ID" value="XM_003718125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEA6"/>
    <dbReference type="STRING" id="242507.G4NEA6"/>
    <dbReference type="GeneID" id="2674292"/>
    <dbReference type="KEGG" id="mgr:MGG_00811"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00811"/>
    <dbReference type="eggNOG" id="KOG2486">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_484906_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEA6"/>
    <dbReference type="OMA" id="ESESICF"/>
    <dbReference type="OrthoDB" id="391988at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052279">
        <property type="entry name" value="EngB_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46498">
        <property type="entry name" value="GTP-BINDING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46498:SF1">
        <property type="entry name" value="GTP-BINDING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EngB-type G" evidence="6">
        <location>
            <begin position="118"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="436"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="507"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA48589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="562" mass="60654" checksum="2A78B45B5F887B56" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEU7</accession>
    <name>G4NEU7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_00041</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719104.1">
        <property type="nucleotide sequence ID" value="XM_003719056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEU7"/>
    <dbReference type="SMR" id="G4NEU7"/>
    <dbReference type="GeneID" id="2675001"/>
    <dbReference type="KEGG" id="mgr:MGG_00041"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00041"/>
    <dbReference type="eggNOG" id="ENOG502SKN0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067676_7_0_1"/>
    <dbReference type="InParanoid" id="G4NEU7"/>
    <dbReference type="OMA" id="RSMKARF"/>
    <dbReference type="OrthoDB" id="4863010at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43167">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43167:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G01830)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13578">
        <property type="entry name" value="Methyltransf_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA49520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="238" mass="25851" checksum="AD7585537E1925E8" modified="2011-12-14" version="1">MYSTNPDLDKALSSITGSNRALETLARLHEQALAEPPFVSTDARASETETREEALRRHTRELFVALDPDKAALAYLLVRGSGARCVVEAGTSFGVSTIWLALAVGQNAGDDAGVARVIATENEPEKAARARENWAAAGEDVARWIELREGDILETLKQGLPRVDLLLLDIWTPLALPTLKLVQPMMKKGAMVIVDNIEDAKSGYRDLLDYVDQPDSGFNMTVLPYNGGLGLLVYTGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF91</accession>
    <name>G4NF91_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719640.1">
        <property type="nucleotide sequence ID" value="XM_003719592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF91"/>
    <dbReference type="SMR" id="G4NF91"/>
    <dbReference type="STRING" id="242507.G4NF91"/>
    <dbReference type="GeneID" id="2677692"/>
    <dbReference type="KEGG" id="mgr:MGG_04183"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04183"/>
    <dbReference type="eggNOG" id="ENOG502SII2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038611_0_0_1"/>
    <dbReference type="InParanoid" id="G4NF91"/>
    <dbReference type="OMA" id="MSESEGM"/>
    <dbReference type="OrthoDB" id="3926760at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="398" mass="43317" checksum="05AF96E8AF40C1B1" modified="2011-12-14" version="1">MPPINHAAISVGVVAVSVAVAAAYAVYENPEFRRMADDLRRRIAIALHSLGDGIQPDELEPRFNRPEDADGFLQSRADAGVDADEETKRRQRDELMYWNAVRLEKQEKADNEKQTEDEESSFQRNSIYSSTTFDSFLQRDKTGEQGTYVLNTGADPRPNDEGLIRRRGGGSEGVRGLNSSFFSANPFSDEHGIDMDDDHFAANVRTMSPEKDEAMSDIYNATAPPSPSRAAFVTSTSADHNIATILFDAQQHVERLEQEVKARSDSSLTMELEPSKAEDTQSVDNEGTRDAYASIQAWAQGSQNSTKGFYSPLPTTPEAPLSEAEMVSEGALTPTDSMSVISAPQGAGNESTSARGADTKSQASYDLVSDDEDNIPTPVSWSEIGSVVSEHDVGPVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFE8</accession>
    <name>G4NFE8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719543.1">
        <property type="nucleotide sequence ID" value="XM_003719495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFE8"/>
    <dbReference type="GeneID" id="12985999"/>
    <dbReference type="KEGG" id="mgr:MGG_17656"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17656"/>
    <dbReference type="HOGENOM" id="CLU_1337740_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFE8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="205" mass="22600" checksum="EB916C7228999E4C" modified="2011-12-14" version="1">MPTTLSAPVYVPSASRKFRKAGDTPYMSIHSLTRRRFPVRVRSMGRLSHTIPPRPTVHGVYQGCEPRPCPRFLLPVTQSRLQQWADHVLLSGPFGDCRAGTVLPVHVQLTNPRNGTTSSLQAIPEAFRGRTPAFPAGKVFCATLARIARLGLVLCASMRVARRTADRTLPSPRSVENSSKGRSVDYTWVLRGKAFRVVTVLRATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFF0</accession>
    <name>G4NFF0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719545.1">
        <property type="nucleotide sequence ID" value="XM_003719497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFF0"/>
    <dbReference type="STRING" id="242507.G4NFF0"/>
    <dbReference type="GeneID" id="12986001"/>
    <dbReference type="KEGG" id="mgr:MGG_14958"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14958"/>
    <dbReference type="HOGENOM" id="CLU_2097343_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFF0"/>
    <dbReference type="OrthoDB" id="417125at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="116" mass="13153" checksum="A843F57080A4E962" modified="2011-12-14" version="1">MESEHKITSTGTGPQKLDEQKRTGHGKPEVSGPWHVMAAYLTGNSPELRELNALRKRGWENPEGDQFFQRQRKNADHPSAKNAKFFYGLMQKIGDDLQKAVFAFADFGDSFEQKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGH8</accession>
    <name>G4NGH8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719502.1">
        <property type="nucleotide sequence ID" value="XM_003719454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGH8"/>
    <dbReference type="SMR" id="G4NGH8"/>
    <dbReference type="GeneID" id="2677561"/>
    <dbReference type="KEGG" id="mgr:MGG_04308"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04308"/>
    <dbReference type="HOGENOM" id="CLU_3069191_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGH8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.30">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="N1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="53" mass="5766" checksum="91DBC3442857A510" modified="2011-12-14" version="1">MEYPILYSGEIYPGYGIPGPDRVVFVSESCIYAGAMTHDGAPADHPNWFVACT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGJ5</accession>
    <name>G4NGJ5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719519.1">
        <property type="nucleotide sequence ID" value="XM_003719471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGJ5"/>
    <dbReference type="GeneID" id="2677232"/>
    <dbReference type="KEGG" id="mgr:MGG_04291"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04291"/>
    <dbReference type="HOGENOM" id="CLU_2038531_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGJ5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466217" evidence="2">
        <location>
            <begin position="17"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="121" mass="12591" checksum="56E2BC41940A157D" modified="2011-12-14" version="1">MKGFTVIVAIAGSAYAQTTGDVPQIAESCLSHAVAAAGCDITKTASNIRADGNLCVIKHRSAHVALSMCPVVNISPGPRALLNNNIPCPQTKSPLPSKRSADNPTDNEARPTSVNPNFWAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH13</accession>
    <name>G4NH13_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Decapping nuclease</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_12119</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA. The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay. Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs. Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1). Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5'-end triphosphate to release pyrophosphates. Stimulates exoribonuclease activity of Rat1, allowing it to degrade RNAs with stable secondary structure more effectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside-ribonucleotide in mRNA + H2O = a (N(7)-methyl 5'-triphosphoguanosine)-nucleoside + a 5'-end phospho-ribonucleoside in mRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66928"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17313"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:172876"/>
            <dbReference type="ChEBI" id="CHEBI:172877"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:66929"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60880"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:60881"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78683"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78684"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXO/Dom3Z family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719891.1">
        <property type="nucleotide sequence ID" value="XM_003719843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH13"/>
    <dbReference type="FunCoup" id="G4NH13">
        <property type="interactions" value="634"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NH13"/>
    <dbReference type="GeneID" id="5049880"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12119"/>
    <dbReference type="eggNOG" id="KOG1982">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024877_4_1_1"/>
    <dbReference type="InParanoid" id="G4NH13"/>
    <dbReference type="OMA" id="VVTWRGH"/>
    <dbReference type="OrthoDB" id="5853397at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034353">
        <property type="term" value="F:mRNA 5'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110155">
        <property type="term" value="P:NAD-cap decapping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013961">
        <property type="entry name" value="RAI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039039">
        <property type="entry name" value="RAI1-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395:SF9">
        <property type="entry name" value="DECAPPING AND EXORIBONUCLEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395">
        <property type="entry name" value="DOM-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08652">
        <property type="entry name" value="RAI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RAI1-like" evidence="8">
        <location>
            <begin position="23"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="377" mass="43268" checksum="CF3B8CD7202AE40B" modified="2011-12-14" version="1">MSAHVTFQVQPISKFAGPSEPVRRPKEFACFSYDADHKFRLDDSSMKWYYPPRLGADLSEGFESFDKLDEGASAEHIDSLLQTIIAHEQRIGKKIDAHVVTWRGIVTKLMASPYEDRDGFDLNATLYQDCVFIEEDYASRMESKKAQDSEPWKSPIPREVMTFWGYKFETLSTIPKPWGETSRDYIEGRELEPTNNKEQYCSVVRTGIGKTILCIGGEVDAIWDSKPSTPGPINWVELKTSAEVRNDRDAANFERKLLKWWIQSFLLGVPKIVVGFRTRDGHLTRVDEMETNVIPANVQQRGRSWNGDTCINFCSAVLDWIRSTMDDDGVWRIRRRARSSVIEMFKIEETGHGRVLTDDFINWRIKLSLGVEPQPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH61</accession>
    <name>G4NH61_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cell division protease ftsH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_03926</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719938.1">
        <property type="nucleotide sequence ID" value="XM_003719890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH61"/>
    <dbReference type="SMR" id="G4NH61"/>
    <dbReference type="FunCoup" id="G4NH61">
        <property type="interactions" value="1090"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NH61"/>
    <dbReference type="GeneID" id="2677464"/>
    <dbReference type="KEGG" id="mgr:MGG_03926"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03926"/>
    <dbReference type="eggNOG" id="KOG0734">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_9_3_1"/>
    <dbReference type="InParanoid" id="G4NH61"/>
    <dbReference type="OMA" id="RATIDVC"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031942">
        <property type="term" value="C:i-AAA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141164">
        <property type="term" value="P:mitochondrial protein quality control"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045041">
        <property type="term" value="P:protein import into mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000175">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FTSH 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048438">
        <property type="entry name" value="Yme1-like_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21232">
        <property type="entry name" value="Yme1-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="16" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 16" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="308"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="714"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="737"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA47571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="748" mass="81459" checksum="623DC9D5BB0FAC95" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHU9</accession>
    <name>G4NHU9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720176.1">
        <property type="nucleotide sequence ID" value="XM_003720128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHU9"/>
    <dbReference type="GeneID" id="12987210"/>
    <dbReference type="KEGG" id="mgr:MGG_17782"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17782"/>
    <dbReference type="HOGENOM" id="CLU_2850173_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHU9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="65" mass="7251" checksum="C2A0521968BCCD0C" modified="2011-12-14" version="1">MDTNKQPPGMEPEAWNLMIVKGERGSEGRTDQSPGLPNYHLQNLIICVNNITAQLKSSNLARPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHY7</accession>
    <name>G4NHY7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_09397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720214.1">
        <property type="nucleotide sequence ID" value="XM_003720166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHY7"/>
    <dbReference type="SMR" id="G4NHY7"/>
    <dbReference type="GeneID" id="2680368"/>
    <dbReference type="KEGG" id="mgr:MGG_09397"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09397"/>
    <dbReference type="HOGENOM" id="CLU_1806558_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHY7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="143" mass="15832" checksum="59E4261DE3D790EE" modified="2011-12-14" version="1">MRRKDFGIKLLMNVNLQAPSLDPSQAPFDYVCSLKSKNTTQTSDVQAQQRIPSLIIDGGCPLESSCCCSGGSFRYGMIISIFLCPRRHKQTVLAILEKAGPSKQVTEMLHAMEKALIAEIQDVEDVMGVKNPRIRELFNAMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHZ7</accession>
    <name>G4NHZ7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720224.1">
        <property type="nucleotide sequence ID" value="XM_003720176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHZ7"/>
    <dbReference type="GeneID" id="12987239"/>
    <dbReference type="KEGG" id="mgr:MGG_17790"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17790"/>
    <dbReference type="HOGENOM" id="CLU_2347108_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHZ7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="97" mass="11444" checksum="915FF0C4C33D684D" modified="2011-12-14" version="1">MLDTRATEAILIIMSSQVFQPEIARASVVPIQDDEFQPSLTRVATLSTHFPHREPLGKKKKWQMVEPELKIQEPNHDERRTQIFDFKDRFKDQFPTH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2024-10-02" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIR3</accession>
    <name>CHS2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin synthase 2</fullName>
            <ecNumber evidence="4">2.4.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Chitin-UDP acetyl-glucosaminyl transferase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Class-II chitin synthase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CHS2</name>
        <name type="ORF">MGG_04145</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2012" name="PLoS Pathog." volume="8" first="e1002526" last="e1002526">
            <title>Different chitin synthase genes are required for various developmental and plant infection processes in the rice blast fungus Magnaporthe oryzae.</title>
            <authorList>
                <person name="Kong L.A."/>
                <person name="Yang J."/>
                <person name="Li G.T."/>
                <person name="Qi L.L."/>
                <person name="Zhang Y.J."/>
                <person name="Wang C.F."/>
                <person name="Zhao W.S."/>
                <person name="Xu J.R."/>
                <person name="Peng Y.L."/>
            </authorList>
            <dbReference type="PubMed" id="22346755"/>
            <dbReference type="DOI" id="10.1371/journal.ppat.1002526"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>INDUCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="4 7">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer (Probable). Plays an important role in cell wall integrity and has distinct functions in invasive hyphae and vegetative hyphae, but is not involved in plant infection (PubMed:22346755).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="4">Expression is low in vegetative hyphae, conidia, appressoria, and infected rice leaves.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="4">Leads to increased sensitivity to Calcofluor white, Congo red, and Nikkomycin Z (PubMed:22346755). Results in a 20% reduction in vegetative growth (PubMed:22346755). Reduces conidiation over 5-fold (PubMed:22346755). Does not significantly changes in the chitin content in vegetative hyphae, nor in conidia (PubMed:22346755).</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the chitin synthase family. Class II subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="4"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719685.1">
        <property type="nucleotide sequence ID" value="XM_003719637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIR3"/>
    <dbReference type="SMR" id="G4NIR3"/>
    <dbReference type="FunCoup" id="G4NIR3">
        <property type="interactions" value="80"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NIR3"/>
    <dbReference type="EnsemblFungi" id="MGG_04145T0">
        <property type="protein sequence ID" value="MGG_04145T0"/>
        <property type="gene ID" value="MGG_04145"/>
    </dbReference>
    <dbReference type="GeneID" id="2677655"/>
    <dbReference type="KEGG" id="mgr:MGG_04145"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04145"/>
    <dbReference type="eggNOG" id="KOG2571">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004760_1_1_1"/>
    <dbReference type="InParanoid" id="G4NIR3"/>
    <dbReference type="OMA" id="TTMRETE"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902404">
        <property type="term" value="P:mitotic actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF38">
        <property type="entry name" value="CHITIN SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000460877" description="Chitin synthase 2">
        <location>
            <begin position="1"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="639"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="681"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="716"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="752"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="791"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="820"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="918"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="952"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="174"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="4">
        <source>
            <dbReference type="PubMed" id="22346755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="5">
        <source>
            <dbReference type="PubMed" id="22346755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="6"/>
    <evidence type="ECO:0000305" key="7">
        <source>
            <dbReference type="PubMed" id="22346755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1029" mass="115157" checksum="24B13BD7ECD12BC8" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJK2</accession>
    <name>G4NJK2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721161.1">
        <property type="nucleotide sequence ID" value="XM_003721113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJK2"/>
    <dbReference type="GeneID" id="12984915"/>
    <dbReference type="KEGG" id="mgr:MGG_15030"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15030"/>
    <dbReference type="HOGENOM" id="CLU_2038533_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJK2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="121" mass="13636" checksum="0BE4AF34DFD7F969" modified="2011-12-14" version="1">MQWVAAGVLSVSAHGYLRRRHLIQKMSFQRALLRDLPIVTRGNVCAMKDVAGFVFTAIVINKTPYAFSYEDDKQQLVENWDLASATQFGHSVCVSRAWGCYRATRRHVMEGGDIEDRDTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJR1</accession>
    <name>G4NJR1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720471.1">
        <property type="nucleotide sequence ID" value="XM_003720423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJR1"/>
    <dbReference type="GeneID" id="12987385"/>
    <dbReference type="KEGG" id="mgr:MGG_15440"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15440"/>
    <dbReference type="HOGENOM" id="CLU_2996936_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJR1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA45728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="57" mass="6444" checksum="58208347213186CE" modified="2011-12-14" version="1">MHCWCYAPDPNVPLNPYFKLLDDKGRGEEESVILKINFVNPMGRAVDILQVPAGKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL30</accession>
    <name>G4NL30_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RTA1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_02988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720706.1">
        <property type="nucleotide sequence ID" value="XM_003720658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL30"/>
    <dbReference type="SMR" id="G4NL30"/>
    <dbReference type="GeneID" id="2682541"/>
    <dbReference type="KEGG" id="mgr:MGG_02988"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02988"/>
    <dbReference type="eggNOG" id="ENOG502RNSS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_721753_0_0_1"/>
    <dbReference type="InParanoid" id="G4NL30"/>
    <dbReference type="OMA" id="CTLITVR"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF34">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA45963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="43258" checksum="248BADFA1990D4BA" modified="2011-12-14" version="1">MTPTANREEHVAPAVEMGRRVPARVGSDKALVRPFKGAWMRAGTERFIRLTARKVHPSSPRPRIAIRYSRTLQGCGGLIKYNESGAYCIGITSSDSRDFLAIAFHALARLAEFSWSQKRVANIRRHQCPSTYTSMPQPREHPPIFFAVAFGLSAIFHIYQGYRPLVIFIMSQVFTFARLLSWSLQTTIYWAVFSFYFVPHHAPLKHSHVLATFGGLMVVVEANLNALGVALAANSSSGPDQQALGKIFFITAVSLQVILIIVFVALSAILHRRCIRAEVPSRAINTLLPVMYTSMDLIFARCIYRLVEHTGNTKVDLDNPETLWSLSPILRYEVYFYVLEASLMLINSWVWNLWHPGRFLPDVVGIRFDPDITSMQSRCSIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G5EGW1</accession>
    <name>G5EGW1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g581</name>
        <name evidence="3" type="ORF">MGG_02826</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720912.1">
        <property type="nucleotide sequence ID" value="XM_003720864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EGW1"/>
    <dbReference type="SMR" id="G5EGW1"/>
    <dbReference type="STRING" id="242507.G5EGW1"/>
    <dbReference type="GeneID" id="2682379"/>
    <dbReference type="KEGG" id="mgr:MGG_02826"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02826"/>
    <dbReference type="eggNOG" id="KOG2852">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_14_1_1"/>
    <dbReference type="OMA" id="GPWTPQV"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF185">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_3G02360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="419" mass="45075" checksum="054130ABA0D9485E" modified="2011-12-14" version="1">MSTVIVGSGIIGVATAFYLSKSEAPSSIHLVDNSDVLFSSASGFTGGFLAKDWFNGAMLRLAQLSFQEHQRLAREQGGPEKWGYRTGTAFSYIPAPETADAAKTISGDWLRQGTSRSEEAANSEEPAQVEEQAPAWLRRYKGDRIDCLSVDTVAQVDPAALCRFLLSQCIDAGVHLHQPATVLSVHADNRGELASVRIADTKSSLETDIPCTRVVVTAGAWSPQVFKTLFPDSPVERLPIFSLAGYSLLLKTPHWKANTVDTGFQRSRAVYSARMSGMAPEMFSWGDGTVYIAGLNDAAMPLPKVATEAKKQIQPESVERLKDTARKLVEGELEFTREALCFRPVTDIGTPIISRVPDEMLGNGVTTRGGGQGGVFLVAGHGPWGINLSLGTGKVAAEMVMGRGSSIGDVDFFALSRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G5EGW8</accession>
    <name>G5EGW8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g305</name>
        <name evidence="3" type="ORF">MGG_02591</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721209.1">
        <property type="nucleotide sequence ID" value="XM_003721161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EGW8"/>
    <dbReference type="GeneID" id="2682331"/>
    <dbReference type="KEGG" id="mgr:MGG_02591"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02591"/>
    <dbReference type="eggNOG" id="ENOG502RKIA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_167703_0_0_1"/>
    <dbReference type="OrthoDB" id="3551791at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834219" evidence="1">
        <location>
            <begin position="18"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="114" mass="11699" checksum="0A56DD332C16A336" modified="2011-12-14" version="1">MLANNILILGLAAIASAQSFVGFAAGGITCETGVSATQDEVVAAMVGPKGTLTEKRADNLATKGCNKVKAPLFKVSVQKKFILSYAFDKPTNTYTLCSVSIGGTGRGPQCSAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G5EGX7</accession>
    <name>G5EGX7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pre-rRNA-processing protein IPI3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGCH7_ch7g852</name>
        <name evidence="9" type="ORF">MGG_03057</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15</strain>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">70-15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the WD repeat IPI3/WDR18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720624.1">
        <property type="nucleotide sequence ID" value="XM_003720576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EGX7"/>
    <dbReference type="SMR" id="G5EGX7"/>
    <dbReference type="FunCoup" id="G5EGX7">
        <property type="interactions" value="423"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EGX7"/>
    <dbReference type="GeneID" id="2682610"/>
    <dbReference type="KEGG" id="mgr:MGG_03057"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03057"/>
    <dbReference type="eggNOG" id="KOG0646">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025946_0_0_1"/>
    <dbReference type="OMA" id="GVNARIY"/>
    <dbReference type="OrthoDB" id="756370at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120330">
        <property type="term" value="C:rixosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000929">
        <property type="entry name" value="Ribosomal assembly complex component Ipi3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045227">
        <property type="entry name" value="WDR18/Ipi3/RID3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763">
        <property type="entry name" value="WD-REPEAT PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 5 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="122"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="422"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EAQ71445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA45881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="462" mass="48716" checksum="0D806B003E31F4CC" modified="2011-12-14" version="1">MLSEEFVSSLCGGPLSSNTSIAKDVGIYVHTLSPAYSVKSAFKKNSAAPNCVAVNGSHIFAAQHEKAALHVYSRIRGNQEAYVPFPERIRCVALAGDVLILGTAEGRIMLWEFCTGRLVSTPACHVQPVTCLAVTPHSVLSGSDDSNVHVWSLAQLLELDIVAEQAPERTLSNHRAAITALAASSGADGGSGATDSTLCVSASKDKTCVVWNYRTGLPLRTLLFPASPLCLSLDPCTRALTLAADDGSVYLVELFGEPALLGPHAAEAASTVVQVTSPFGMAPPEAGPASCLATSYDGTVLLSGHAKGKILQWSLADNSPPTELADLNAAVSNLVFVPPLPSSNFGQSTTKSPTIVKPAANADKTYAFTAHFNVDLGDSTEPSRFDKLMNTPGFSEDVLKQAILAFQQPSATATPAVAANGSSDDRNEVEELRRQNEELLQIVNEQKALYKQVLQRQAGAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHN5</accession>
    <name>G5EHN5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g642</name>
        <name evidence="3" type="ORF">MGG_02882</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720848.1">
        <property type="nucleotide sequence ID" value="XM_003720800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHN5"/>
    <dbReference type="STRING" id="242507.G5EHN5"/>
    <dbReference type="GeneID" id="2682435"/>
    <dbReference type="KEGG" id="mgr:MGG_02882"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02882"/>
    <dbReference type="HOGENOM" id="CLU_547539_0_0_1"/>
    <dbReference type="OMA" id="PCPDYAR"/>
    <dbReference type="OrthoDB" id="5208788at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="498" mass="56177" checksum="95542FCB2C852E90" modified="2011-12-14" version="1">MSIRTKRNILVCFNPVGTLYKPRPISAADYTALARKCGISDLDGAKLERTLADAIIHFTFDETRSDAAAEGHQFLRPGGYSWWRNVVNYAVKRALLPGQGLPADLIPKILALVSPAEGFTLGEQDLQKSLWRLKRTFNPSKSSGSSSFVDKLVVGVTENTRHPRNLERTSRVLSALGVSVAPLRYHHYAGLHTNYGAHGDIPDELYQWEQRKAAQRALEDSVRRRSLRFGSNWSSLIRPYDLDFVCATRNFASGDPTPSLHAAERLTAMMVTNKSPWRLPWAESQINRRDGDWLKFYVVNNSNKDTRDIIDSGWTPVLLEDNSNTVRSAPGVTPRRPDWESLARLSDAKLDPESPSGCKLQTYRVGSVDELSRWLSEEMRPKKFVLGRGAVDTKGYKALEDADMEPTVSGWTAEDILKKAFDQRLKRRTASQAKPSAKDRIITLLDSMMKRRFSPDISPRTDVVDETTPDVPAQRERPQEDDVLQRLVKISKTEKSRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2021-06-02" modified="2025-04-09" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHQ6</accession>
    <name>HTR2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Host transcription reprogramming factor 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Secreted nuclear effector HTR2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HTR2</name>
        <name type="ORF">MGCH7_ch7g1049</name>
        <name type="ORF">MGG_10280</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2020" name="Nat. Commun." volume="11" first="5845" last="5845">
            <title>Two nuclear effectors of the rice blast fungus modulate host immunity via transcriptional reprogramming.</title>
            <authorList>
                <person name="Kim S."/>
                <person name="Kim C.Y."/>
                <person name="Park S.Y."/>
                <person name="Kim K.T."/>
                <person name="Jeon J."/>
                <person name="Chung H."/>
                <person name="Choi G."/>
                <person name="Kwon S."/>
                <person name="Choi J."/>
                <person name="Jeon J."/>
                <person name="Jeon J.S."/>
                <person name="Khang C.H."/>
                <person name="Kang S."/>
                <person name="Lee Y.H."/>
            </authorList>
            <dbReference type="PubMed" id="33203871"/>
            <dbReference type="DOI" id="10.1038/s41467-020-19624-w"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>INDUCTION</scope>
        <scope>SUBCELLULAR LOCATION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Secreted effector that translocates into the nuclei of host cells to reprogram the expression of immunity-associated genes by binding to effector binding elements (EBEs) in rice (PubMed:33203871). Binds the 5'-CCACCTCC-3' EBE of promoters from targeted rice genes and probably recruits a yet to be determined host repressor (PubMed:33203871). Causes ambivalent immunity with increased susceptibility to the hemibiotrophic pathogens Magnaporthe oryzae and Xanthomonas oryzae pv. oryzae, but enhances resistance to Cochliobolus miyabeanus, a necrotrophic pathogen (PubMed:33203871).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Host nucleus</location>
        </subcellularLocation>
        <text evidence="4">Secreted via the biotrophic interfacial complex (BIC) and translocated into the nuclei of initially penetrated and surrounding cells.</text>
    </comment>
    <comment type="induction">
        <text evidence="4">Expressed during multiple stages of host plant infection, including prepenetration, early biotrophy, late biotrophy, transition and necrotrophy.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="4">Does not affect vegetative growth, conidiation, conidial germination, nor appressorium formation, but leads to significantly reduced virulence to rice.</text>
    </comment>
    <comment type="online information" name="Protein Spotlight">
        <link uri="https://www.proteinspotlight.org/back_issues/247/"/>
        <text>Sapped - Issue 247 of May 2022</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720559.1">
        <property type="nucleotide sequence ID" value="XM_003720511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHQ6"/>
    <dbReference type="EnsemblFungi" id="MGG_10280T0">
        <property type="protein sequence ID" value="MGG_10280T0"/>
        <property type="gene ID" value="MGG_10280"/>
    </dbReference>
    <dbReference type="GeneID" id="2681932"/>
    <dbReference type="KEGG" id="mgr:MGG_10280"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10280"/>
    <dbReference type="HOGENOM" id="CLU_2171573_0_0_1"/>
    <dbReference type="InParanoid" id="G5EHQ6"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042025">
        <property type="term" value="C:host cell nucleus"/>
        <property type="evidence" value="ECO:0000269"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085039">
        <property type="term" value="C:hyphal membrane"/>
        <property type="evidence" value="ECO:0000269"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0000269"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000979">
        <property type="term" value="F:RNA polymerase II core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140403">
        <property type="term" value="P:effector-mediated suppression of host innate immune response"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-1048">Host nucleus</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834276" description="Host transcription reprogramming factor 2">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C2H2-type" evidence="2">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="4">
        <source>
            <dbReference type="PubMed" id="33203871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="5">
        <source>
            <dbReference type="PubMed" id="33203871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EAQ71642.1"/>
        </source>
    </evidence>
    <sequence length="110" mass="11989" checksum="9DA0B9C41EE973DD" modified="2011-12-14" version="1" precursor="true">MHLKASSILALLVIGANAYPASANSAAALVPEPQQPEAPAVAGSTVGAQVDIHHPRLEARYGRDEPQIMCGYCGKRFWNKPDLEKHIKLKPSKGGHKGQPYKEHSWNRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHV4</accession>
    <name>G5EHV4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g263</name>
        <name evidence="3" type="ORF">MGG_02546</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721255.1">
        <property type="nucleotide sequence ID" value="XM_003721207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHV4"/>
    <dbReference type="GeneID" id="2682849"/>
    <dbReference type="KEGG" id="mgr:MGG_02546"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02546"/>
    <dbReference type="HOGENOM" id="CLU_1768477_0_0_1"/>
    <dbReference type="OrthoDB" id="10450031at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834282" evidence="1">
        <location>
            <begin position="23"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="147" mass="15143" checksum="B8976DE872FFDFDC" modified="2011-12-14" version="1">MQPGTFLASALAAALVPAGALAATPPGSPSARLAGTSNARLAGISNTNPPGGAPRPRQQCFLSADLGPDVMGQPTLLEATPFVNDMFDFHGYRCQMGKDCSHVRCRGFPAAFKMTARNYPDGKGPLGTSAGDSFVPGPVVKVYPAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHW0</accession>
    <name>G5EHW0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g178</name>
        <name evidence="2" type="ORF">MGG_18045</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721326.1">
        <property type="nucleotide sequence ID" value="XM_003721278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHW0"/>
    <dbReference type="GeneID" id="12985920"/>
    <dbReference type="KEGG" id="mgr:MGG_18045"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18045"/>
    <dbReference type="HOGENOM" id="CLU_2483798_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ70771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="87" mass="9832" checksum="BB129EC817B26E35" modified="2011-12-14" version="1">MSNVVFESSIPPPSHELSTDDHGIQVASLCTGFKFFQRVFLATSRSNSELKIAQLPLYIGYLDRPHDPKLVDYPVRKPCPISKICQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHX2</accession>
    <name>G5EHX2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08246</name>
        <name evidence="1" type="ORF">MGG_12488</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715839.1">
        <property type="nucleotide sequence ID" value="XM_003715791.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715841.1">
        <property type="nucleotide sequence ID" value="XM_003715793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHX2"/>
    <dbReference type="GeneID" id="5051080"/>
    <dbReference type="GeneID" id="5051081"/>
    <dbReference type="KEGG" id="mgr:MGG_08246"/>
    <dbReference type="KEGG" id="mgr:MGG_12488"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08246"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12488"/>
    <dbReference type="HOGENOM" id="CLU_1261737_0_0_1"/>
    <dbReference type="OrthoDB" id="5266991at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="219" mass="22740" checksum="C086AD8C3DE738B0" modified="2011-12-14" version="1">MHFFQNTTTLAQLTLKPTAKALKAAMNIACDILMEIAEKAAKLIPRLVGQAVKLSSEAVDGAKFLAEKVGENIPDAATQIAQDIPTNYGKAAAVILGISGIAMVAAPAVLTLPALGAVGFSASRPIAGEFGYWGKTFRNGDKQSARRIRLTAVDGSSSRGAYVQTAELSVVCNHGDEVPNKCGLDGTGGWLLSIASRVILATVSGEEVEGAGFEPTLLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-02-01" modified="2025-06-18" version="113" xmlns="https://uniprot.org/uniprot">
    <accession>P33281</accession>
    <accession>A4QSA4</accession>
    <accession>G4ML13</accession>
    <name>ERG2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>C-8 sterol isomerase</fullName>
            <ecNumber>5.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Delta-8--delta-7 sterol isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">ERG2</name>
        <name type="ORF">MGG_08624</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1994" name="Curr. Genet." volume="25" first="531" last="537">
            <title>Isolation of the ERG2 gene, encoding sterol delta 8--&gt;delta 7 isomerase, from the rice blast fungus Magnaporthe grisea and its expression in the maize smut pathogen Ustilago maydis.</title>
            <authorList>
                <person name="Keon J.P.R."/>
                <person name="James C.S."/>
                <person name="Court S."/>
                <person name="Baden-Daintree C."/>
                <person name="Bailey A.M."/>
                <person name="Burden M."/>
                <person name="Hargreaves J.A."/>
            </authorList>
            <dbReference type="PubMed" id="8082205"/>
            <dbReference type="DOI" id="10.1007/BF00351674"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text>Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.</text>
    </comment>
    <comment type="pathway">
        <text>Steroid metabolism; ergosterol biosynthesis; ergosterol from zymosterol: step 2/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ERG2 family.</text>
    </comment>
    <dbReference type="EC" id="5.-.-.-"/>
    <dbReference type="EMBL" id="Z22775">
        <property type="protein sequence ID" value="CAA80454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S44061">
        <property type="entry name" value="S33457"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711052.1">
        <property type="nucleotide sequence ID" value="XM_003711004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P33281"/>
    <dbReference type="SMR" id="P33281"/>
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        <property type="interactions" value="147"/>
    </dbReference>
    <dbReference type="STRING" id="242507.P33281"/>
    <dbReference type="EnsemblFungi" id="MGG_08624T0">
        <property type="protein sequence ID" value="MGG_08624T0"/>
        <property type="gene ID" value="MGG_08624"/>
    </dbReference>
    <dbReference type="GeneID" id="2679059"/>
    <dbReference type="KEGG" id="mgr:MGG_08624"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08624"/>
    <dbReference type="eggNOG" id="KOG4143">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_085469_0_0_1"/>
    <dbReference type="InParanoid" id="P33281"/>
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    <dbReference type="OrthoDB" id="347124at2759"/>
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        <property type="reaction ID" value="UER00761"/>
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        <property type="component" value="Chromosome 1"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:ergosterol biosynthetic process"/>
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        <property type="entry name" value="ERG2_sigma1_rcpt-like"/>
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        <property type="entry name" value="SIGMA 1-TYPE OPIOID RECEPTOR-RELATED"/>
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        <property type="entry name" value="SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1"/>
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        <property type="entry name" value="ERG2_Sigma1R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0752">Steroid biosynthesis</keyword>
    <keyword id="KW-0753">Steroid metabolism</keyword>
    <keyword id="KW-0756">Sterol biosynthesis</keyword>
    <keyword id="KW-1207">Sterol metabolism</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000087017" description="C-8 sterol isomerase">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="5"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="221" mass="24721" checksum="8D8478A278E05DDD" modified="1994-02-01" version="1">MSSPISGFLRFVAVLLAVVSPLVYLAEQRLESFYVFDHKHLHELSTQAIAQHGNNTRAIVGHIVDELRARPETTKYISVQEEWVFNNAGGAMGGMYIIHASVTEYLIIFGTAIGTEGHTGRHTADDYFNILTGEQWAYVPGEYEPEVYPAGSVHHLRRGTVKQYKMPEGCFALEYARGWIPPMLFFGFADGLSSTLDFPTLWQTTVVTGREMLGNLMLGKF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-03-18" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>A4R2R1</accession>
    <accession>G4MRW7</accession>
    <accession>G4MRW8</accession>
    <name>NST1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Stress response protein NST1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">NST1</name>
        <name type="ORF">MGG_02456</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (ISOFORMS 1 AND 2)</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May act as a negative regulator of salt tolerance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="alternative products">
        <event type="alternative splicing"/>
        <isoform>
            <id>A4R2R1-1</id>
            <name>1</name>
            <sequence type="displayed"/>
        </isoform>
        <isoform>
            <id>A4R2R1-2</id>
            <name>2</name>
            <sequence type="described" ref="VSP_042192 VSP_042193"/>
        </isoform>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NST1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709248.1">
        <molecule id="A4R2R1-2"/>
        <property type="nucleotide sequence ID" value="XM_003709200.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709249.1">
        <molecule id="A4R2R1-1"/>
        <property type="nucleotide sequence ID" value="XM_003709201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R2R1"/>
    <dbReference type="SMR" id="A4R2R1"/>
    <dbReference type="EnsemblFungi" id="MGG_02456T0">
        <property type="protein sequence ID" value="MGG_02456T0"/>
        <property type="gene ID" value="MGG_02456"/>
    </dbReference>
    <dbReference type="GeneID" id="2681553"/>
    <dbReference type="KEGG" id="mgr:MGG_02456"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02456"/>
    <dbReference type="eggNOG" id="ENOG502QSSK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A4R2R1"/>
    <dbReference type="OrthoDB" id="21629at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06503">
        <property type="entry name" value="ATP-synt_Fo_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051195">
        <property type="entry name" value="Fungal_stress_NST1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025279">
        <property type="entry name" value="NST1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31780:SF10">
        <property type="entry name" value="LD36051P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31780">
        <property type="entry name" value="STRESS RESPONSE PROTEIN NST1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13945">
        <property type="entry name" value="NST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0025">Alternative splicing</keyword>
    <keyword id="KW-0175">Coiled coil</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_0000324453" description="Stress response protein NST1">
        <location>
            <begin position="1"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="308"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="478"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="542"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="613"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="450"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="599"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="343"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="491"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="613"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="689"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="805"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="891"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="923"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="934"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="960"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="984"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1026"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1041"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="splice variant" id="VSP_042192" description="In isoform 2." evidence="4">
        <location>
            <begin position="398"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="splice variant" id="VSP_042193" description="In isoform 2." evidence="4">
        <location>
            <begin position="518"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="1311" mass="143728" checksum="F92A44EC90F1F01A" modified="2012-01-25" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKY1</accession>
    <name>G4MKY1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05379</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710228.1">
        <property type="nucleotide sequence ID" value="XM_003710180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKY1"/>
    <dbReference type="SMR" id="G4MKY1"/>
    <dbReference type="FunCoup" id="G4MKY1">
        <property type="interactions" value="174"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKY1"/>
    <dbReference type="GeneID" id="2676191"/>
    <dbReference type="KEGG" id="mgr:MGG_05379"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05379"/>
    <dbReference type="eggNOG" id="KOG2319">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007625_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKY1"/>
    <dbReference type="OMA" id="TFITNKM"/>
    <dbReference type="OrthoDB" id="300289at2759"/>
    <dbReference type="PHI-base" id="PHI:7991"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
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            <begin position="360"/>
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            <begin position="578"/>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
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    <name>G4ML88_PYRO7</name>
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        <submittedName>
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        <name evidence="2" type="ORF">MGG_06725</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA56824.1"/>
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    </evidence>
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            <dbReference type="EMBL" id="EHA56824.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="429" mass="47295" checksum="59A4015F87397718" modified="2011-12-14" version="1">MSFREFTEEEEAQAEEAFLPEQGCPPPASLSPPDRATPSLPSIIGDILRTKNCVPGSLFLVESIHSQIAPGGPLGQKRKHKQQWIGRRAVRLILGDGELCIQALLVPSLHSLVDGGLIKEGCLVRLDRFRLRVLLRPAPGAPCGPPTVFLVVEEVLVEGDEADKALESKKGLDLDGMRKDDRGRAAKQLGTFPTSGVKIPVFSSVNNEAQDGTEQQSGTLHTRAADALNSSQNIQRLAEHYQTSNYVTTEEPIEARKASETDKDGFSQPLKKPKLDTQDKSTAEPVPSWVSKDLTQPVKLTTLKTIPLLPYKQNWMVNILAIVSELSDVEPSPLRPYTGKQRTARLADPSTGKRVLLTVFLDPENFAPKVGSAVILLGVKNHRFDGGSLKKYASDRPKDGASWWFEDPEDLDLCDVRHLKEWWASNQFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLS4</accession>
    <name>G4MLS4_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">MGG_05452</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
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                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003710266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLS4"/>
    <dbReference type="GeneID" id="2675936"/>
    <dbReference type="KEGG" id="mgr:MGG_05452"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05452"/>
    <dbReference type="eggNOG" id="ENOG502R0UX">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="InParanoid" id="G4MLS4"/>
    <dbReference type="OMA" id="WVCCKCK"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="165" mass="17933" checksum="ACA045E93619CFE0" modified="2011-12-14" version="1">MCTSYYVHYHHLPTCSRPIDIALEYTFCPAATEATTSTTSSPTQRQQGATATHDNQDGQQRRQQRQPCEDLHHDPWASVDLADPCMAGGCFAVSPECGSGLCRLNDLGGRWACCSCGRGGNTYRWCRHRMKKSPDTFCYHTCCENCTADPVGGGGGDSEGSGGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM22</accession>
    <name>G4MM22_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709519.1">
        <property type="nucleotide sequence ID" value="XM_003709471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM22"/>
    <dbReference type="GeneID" id="12984534"/>
    <dbReference type="KEGG" id="mgr:MGG_16169"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16169"/>
    <dbReference type="HOGENOM" id="CLU_3032839_0_0_1"/>
    <dbReference type="InParanoid" id="G4MM22"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="55" mass="6583" checksum="5FDE128E1F5DE847" modified="2011-12-14" version="1">MATFSYLGVAKNFGDRRIRHRNYYAEQGLLELRHWIGYCNLWLLSCLFGWKVPSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM31</accession>
    <name>G4MM31_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709528.1">
        <property type="nucleotide sequence ID" value="XM_003709480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM31"/>
    <dbReference type="GeneID" id="12984541"/>
    <dbReference type="KEGG" id="mgr:MGG_16176"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16176"/>
    <dbReference type="InParanoid" id="G4MM31"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="118" mass="12705" checksum="CC0B337EC8B2E4B4" modified="2011-12-14" version="1">MSGPFGDCRAGTVLPVHVQLTNPRNGITSSLQAIPEAFRGRTPAFPAGKVFSCFATLARIARLGLVLCASMRVARRAADRTLPSPRSMENSSKGRSVDYTWVLRGKAFRVVTVLRATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM35</accession>
    <name>G4MM35_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_14569</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709532.1">
        <property type="nucleotide sequence ID" value="XM_003709484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM35"/>
    <dbReference type="SMR" id="G4MM35"/>
    <dbReference type="GeneID" id="5051438"/>
    <dbReference type="KEGG" id="mgr:MGG_14569"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14569"/>
    <dbReference type="eggNOG" id="ENOG502SH56">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_472563_0_0_1"/>
    <dbReference type="InParanoid" id="G4MM35"/>
    <dbReference type="OMA" id="WPRSSEW"/>
    <dbReference type="OrthoDB" id="10071592at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535">
        <property type="entry name" value="FLUG DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37535:SF3">
        <property type="entry name" value="FLUG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="397"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="433"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA56920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="502" mass="59008" checksum="A2B8CB2D62A6526A" modified="2011-12-14" version="1">MPENISSNSGPPPLYSQPMLFWLHISNWAKRAGFVNGIGGLHNARREALIKANGDNGQSVEQLQLFADHKNSSVFQRYYLGAINIIDGAANYLGMDTKRNLTEDFRSATMEWESDLIWQFPAREFDQLKRDENYVRLTEQIFTYTTLISRGGSTKELEQHTAYRKQAYNDRRKFMRRKLQEYQRFATDQSDWRWDHLPRIIHMMPERQRLLQNLGRKETLRSPTGLSALEDLISLRTGDWRVAYQSQLRPKNGICPVKSCNQKIESLHISQRWQHIYCYYKKHLKANHNFAKFCFLCNHWVTDKQEWEHHCQKHINDEDTPFRCDPIIFRHAYAFQCPHPNCSALVDSTENLWYYLKDIHSVDSAPLKKHPALAETPVAIFKFEPLNDPDSLNKDIWEVEKLLAKWGPKRKSKYLVKWKGFPDEDNTWEPQVYISEDLIKNFESTFEGNHAGVQLFDKRKLGGNVKYLVEWKGRPKCETSWEKAKTLSSARVREYEAGARDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMR1</accession>
    <name>G4MMR1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome biogenesis protein SLX9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_05570</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLX9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710445.1">
        <property type="nucleotide sequence ID" value="XM_003710397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMR1"/>
    <dbReference type="GeneID" id="2676061"/>
    <dbReference type="KEGG" id="mgr:MGG_05570"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05570"/>
    <dbReference type="eggNOG" id="ENOG502SSCK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090035_1_0_1"/>
    <dbReference type="InParanoid" id="G4MMR1"/>
    <dbReference type="OMA" id="HKPGAMK"/>
    <dbReference type="OrthoDB" id="5429132at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028160">
        <property type="entry name" value="Slx9-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15341">
        <property type="entry name" value="SLX9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="144"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA57833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="208" mass="22035" checksum="4C8E13676A479178" modified="2011-12-14" version="1">MAPIAPKKRTSMRAKAARAATSSSSSSAAPQRTEATTSSLLADTKRDRRHIKRSSFLSQIATKSSSGKITKRRRPSKKLAANLESLADALPDLDDLEEQPEPGKVRLKSIRSRPGALKRKEKLVRAEAKNIGLSMAYLNQLKAEGGGASGSGDQDEAMGGAREQDEKAGAGPGKVAPAAPSSTASRWAALRAHISGTMEQNSAFLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN26</accession>
    <name>G4MN26_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710452.1">
        <property type="nucleotide sequence ID" value="XM_003710404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN26"/>
    <dbReference type="GeneID" id="12986343"/>
    <dbReference type="KEGG" id="mgr:MGG_16411"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16411"/>
    <dbReference type="HOGENOM" id="CLU_1305083_0_0_1"/>
    <dbReference type="InParanoid" id="G4MN26"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="211" mass="23688" checksum="0C051C7A12F8E22D" modified="2011-12-14" version="1">MSDIEFKYPVLPGRNQGPCFMWLYRPDRSAVAMADLRNYGETTVTVQGVDITFTVTEDCRAIDKKGNFPEGLFLTVGTKPGSGNSISKPVRSQAQLDTDRQQCPLQLDGEKGQWRTGARGRMKIKSSIRSRLPEIPKPQKQGHKDFYETHANEDFFFEGVPGYVRALTLVHRCQIFNKTAGNINRFFKRQTCSAFKCAESARTSPSNLGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNE3</accession>
    <name>G4MNE3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Association with the SNF1 complex (ASC) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_06930</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
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    <comment type="similarity">
        <text evidence="2">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
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    <dbReference type="HOGENOM" id="CLU_026512_1_0_1"/>
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        <property type="component" value="Chromosome 1"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
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        <property type="entry name" value="ASC_dom"/>
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        <property type="entry name" value="ASC_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="CRP1_MDG1_kinase"/>
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    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04739">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01010">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160219">
        <property type="entry name" value="AMPKBI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Association with the SNF1 complex (ASC)" evidence="5">
        <location>
            <begin position="368"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="77"/>
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    </feature>
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        <location>
            <begin position="78"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="4">
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            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA57057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="479" mass="51133" checksum="32557C8C49272D85" modified="2011-12-14" version="1">MGNQTSAQRQAGASGSSSSAASAQASATGSDPPTRSHSRRDSKHPIPVQIQRAAAPPEQSPAQAQGSTTVPPRSQQYPLSVPSPSSSVSRSAELPSRPLQTGPADGPSKPVAVPNASQAQQNHQPHKAHIPGESAPGGGAGSEALETPEAAMVPTSSMSDLSYITRPPRLPLPIEEEIHTPGSPIISPNENVPSSPTGAVETLDSEETLNRKSSALSSGTYNHEAEEEEEGGDELSVDKTRPTVPFRLEWPHGGEKVYVTGTIFQWNRKHRLHPVEGKPGHFAATINILPGTHHVRFLVDGQMQTSTELPVTVDFGNNLVNYIEVSVTEPTPPGIVQPDAPEKKVSQQELAGSRGPSQIDEKTVRYKEVDPKEVFEHEIPTYLVDFDQPEDSHAYHVSVGAIEKLPAAPALPGFLSKPILNAAVLIKDDNSVLNMPNHTVLNHLATSSIKNNILAVSATTRYKSKYVTTIIYKPTGQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNV3</accession>
    <name>G4MNV3_PYRO7</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16229</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003709674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNV3"/>
    <dbReference type="GeneID" id="12985250"/>
    <dbReference type="KEGG" id="mgr:MGG_16229"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16229"/>
    <dbReference type="HOGENOM" id="CLU_3069171_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNV3"/>
    <dbReference type="OrthoDB" id="4789510at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="53" mass="5266" checksum="B104FB8C19BA493E" modified="2011-12-14" version="1">MASVSMALSGKGGPCKNDGDCIRCLNGKPLICDQPADGSPFVCKVAGGACQPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNX0</accession>
    <name>G4MNX0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709739.1">
        <property type="nucleotide sequence ID" value="XM_003709691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNX0"/>
    <dbReference type="GeneID" id="2685161"/>
    <dbReference type="KEGG" id="mgr:MGG_06988"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06988"/>
    <dbReference type="HOGENOM" id="CLU_1034671_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNX0"/>
    <dbReference type="OMA" id="NTPGIPW"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="269" mass="27154" checksum="CD402C24E1E04D9A" modified="2011-12-14" version="1">MVRHYQLYGTGTFSPSDLISPGFSTIHSTGTLPYCHTFFYGSSGRYPAFTCGGTSRTAPSVYLTVKPGTTRFFATSTSLATLRTTVTSSNGAAVTKVVTVTPTGPTNGRTGDVDESGGASSGSLQPSNNGGGSDNGGGGSSSANTGAIVGGAVGGAAVLAVFALAAVLLYRRRKKNTSHPDGASAGPSGSGYYPMSPSQPDSTAFTPSSYNTPGIPWAQNNGHSVSSVSPGLSLPPNAPHYEGAYPKYPAPMAEVDGTGPNRAHEMAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPF3</accession>
    <name>G4MPF3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16448</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710609.1">
        <property type="nucleotide sequence ID" value="XM_003710561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPF3"/>
    <dbReference type="GeneID" id="12986386"/>
    <dbReference type="KEGG" id="mgr:MGG_16448"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16448"/>
    <dbReference type="HOGENOM" id="CLU_2812888_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPF3"/>
    <dbReference type="OMA" id="RQISACF"/>
    <dbReference type="OrthoDB" id="690068at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="67" mass="7356" checksum="DD69CD17C76F1223" modified="2011-12-14" version="1">MTVVALWSFLDRSDIPSSRRIISFQASRCPDDRGGNVNLTGGGQKKQKRLGASLVGCWLRQISACFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPS2</accession>
    <name>G4MPS2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_09211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709831.1">
        <property type="nucleotide sequence ID" value="XM_003709783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPS2"/>
    <dbReference type="SMR" id="G4MPS2"/>
    <dbReference type="STRING" id="242507.G4MPS2"/>
    <dbReference type="GeneID" id="2680239"/>
    <dbReference type="KEGG" id="mgr:MGG_09211"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09211"/>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_17_5_1"/>
    <dbReference type="InParanoid" id="G4MPS2"/>
    <dbReference type="OMA" id="LCCGGGC"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030586">
        <property type="term" value="F:[methionine synthase] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000027">
        <property type="entry name" value="FAD binding domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000007">
        <property type="entry name" value="Methionine synthase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF84">
        <property type="entry name" value="METHIONINE SYNTHASE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="209"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA57219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="627" mass="69574" checksum="DC0C56F3F5CFA549" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQL5</accession>
    <name>G4MQL5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Candidapepsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_11945</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709117.1">
        <property type="nucleotide sequence ID" value="XM_003709069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQL5"/>
    <dbReference type="SMR" id="G4MQL5"/>
    <dbReference type="STRING" id="242507.G4MQL5"/>
    <dbReference type="MEROPS" id="A01.082"/>
    <dbReference type="GeneID" id="5049731"/>
    <dbReference type="KEGG" id="mgr:MGG_11945"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11945"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_9_4_1"/>
    <dbReference type="InParanoid" id="G4MQL5"/>
    <dbReference type="OMA" id="NMDFFYA"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465310" evidence="8">
        <location>
            <begin position="18"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="95"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA56505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="496" mass="52751" checksum="9FB5C5EF90900DEC" modified="2011-12-14" version="1">MLPAALRLLFAASTATAAIVARDQPQPPLLAHCQVDDNGAAEFGDGYVRYPLRTSERRRPLGDAAIDRAIVSLAKLQARQSVESGVTNIEDGLIYSVDIGVGTPKQEIEVVIDTGSSELWVNPDCNNIENRLSKSMCRAVVHYEPSQSSTAVNLRRNGTITYGSGDVKFNYVADTVTVGSNTAIRNQTFGVATQSTDIFMGIMGLGPRLGRPRESNYSLLLESLVEQKHIRSRAFSLDLRSVNSRTGAVIFGGIDTTKFIGDLSKTPMLSPQETPQGADRYYVHMTSISLSSSGSDSRKVFDKGSTNGVAVFLDSGGTVCQLPQAIFQRIGEAFPGATLDSRSGFYQVDCKDATSANGTIDFGFGDKVIRVGYADFIWRPASNVCVLGVRALASQRGEPILGASFLRAAYVVYDQDNRNLHLAQAANCGDGDIVSIGQGSDAVPSSAKGKCTVASSGDGVTSADEKKNAAGRMADGASWMFLLAAGGLSVLYTSFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQU7</accession>
    <name>G4MQU7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710790.1">
        <property type="nucleotide sequence ID" value="XM_003710742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQU7"/>
    <dbReference type="GeneID" id="2677955"/>
    <dbReference type="KEGG" id="mgr:MGG_04753"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04753"/>
    <dbReference type="HOGENOM" id="CLU_1219893_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQU7"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465318" evidence="2">
        <location>
            <begin position="19"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="227" mass="24716" checksum="9BCEA37DBE49D008" modified="2011-12-14" version="1">MLLEKGIILGLAAASAQCAGSGAACSVDAAGVRGASIKDANVPGAGATLLKRDRSAMRQYYERFPYGTISIPTSGQGQLCGIRAVLSSLEAQMPELGPFYSVEEMRDFANTGETAERHRELIETQSSDNFLEKVESNYPADFLGGVVEEYGRRIKGRNLRLGIRRAQFKDAENGYIIIDTDVDEAGTLWVAHADSHYEGLKPHPGGKSRGHRDSDTHGANKGWLWWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRF5</accession>
    <name>G4MRF5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">propanoyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Propanoyl-CoA C-acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_02409</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.1.176" evidence="2"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709194.1">
        <property type="nucleotide sequence ID" value="XM_003709146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRF5"/>
    <dbReference type="SMR" id="G4MRF5"/>
    <dbReference type="STRING" id="242507.G4MRF5"/>
    <dbReference type="GeneID" id="2681506"/>
    <dbReference type="KEGG" id="mgr:MGG_02409"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02409"/>
    <dbReference type="eggNOG" id="KOG1406">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035425_0_1_1"/>
    <dbReference type="InParanoid" id="G4MRF5"/>
    <dbReference type="OMA" id="PSLYAMM"/>
    <dbReference type="OrthoDB" id="542135at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00829">
        <property type="entry name" value="SCP-x_thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000016">
        <property type="entry name" value="Non-specific lipid-transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055140">
        <property type="entry name" value="Thiolase_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006102">
        <property type="entry name" value="PRK08256.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870:SF1">
        <property type="entry name" value="NON-SPECIFIC LIPID-TRANSFER PROTEIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22691">
        <property type="entry name" value="Thiolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="10">
        <location>
            <begin position="12"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="11">
        <location>
            <begin position="274"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA56582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="463" mass="49215" checksum="D64BA64325B4C919" modified="2011-12-14" version="1">MAPAKPKQPAYVLGVGMTQFIKPRGKVDYTELGFEAGVKAMLDARINYDEVDQGVACYCYGDSTCGQRVFYQFGMTQIPIVNVNNNCSTGSTGLAMARQLVGHGAADCVLVIGFEKMMPGSLQTFFQDRENPTGTSGLMMASTRGYEPKVPGAAQMFGNAGREYMEKYGATLEDFAEIGRVNHEHSARNPYSQFKDQYTLEQVMKSPMIHTPLTKLQCCPTSDGGAAAVVVSQAFLDARPELKANAIKIAGQCMATDGPELFSKSAIDLVGYGMGAHAGRVACAEAGVSPRDCQVCELHDCFSANEMVTLDALGLADKGKAHELVRSGGITYPGGPGRTVVNPSGGLISKGHPLGATGLAQCAELVWHLRGWASNRAVPGTKNALQHNLGLGGAVVVTVYQRADGKEAPKLSEEEIIKAAGVGYNPAVQAKGFTAAQAKAVRSKEKSSEWALQDTLDKVQARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRI3</accession>
    <name>G4MRI3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferroxidase</fullName>
            <ecNumber evidence="3">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_02435</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the frataxin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="3"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709222.1">
        <property type="nucleotide sequence ID" value="XM_003709174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRI3"/>
    <dbReference type="SMR" id="G4MRI3"/>
    <dbReference type="FunCoup" id="G4MRI3">
        <property type="interactions" value="407"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRI3"/>
    <dbReference type="GeneID" id="2681532"/>
    <dbReference type="KEGG" id="mgr:MGG_02435"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02435"/>
    <dbReference type="eggNOG" id="KOG3413">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080880_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRI3"/>
    <dbReference type="OMA" id="YSEHYFN"/>
    <dbReference type="OrthoDB" id="1897642at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034986">
        <property type="term" value="F:iron chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.920.10:FF:000004">
        <property type="entry name" value="Mitochondrial chaperone Frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017789">
        <property type="entry name" value="Frataxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03422">
        <property type="entry name" value="mito_frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="FRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821:SF2">
        <property type="entry name" value="FRATAXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0409">Iron storage</keyword>
    <keyword evidence="6" id="KW-0410">Iron transport</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="47"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA56610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="202" mass="21906" checksum="BE208A5BD804CF3D" modified="2011-12-14" version="1">MSRSAINLMRVARRGVLQNVAVAQRAPLLSTAVPALSKVNAGPAKLSRSVATSTASRMKGIQPESETPEPTEPVESAYVPKTPAPLEESEYHDIADEYLDNVLSKLEDVAEQRPDVDVEYSSGVLTLAFPPLGTYVINKQPPNKQIWLSSPVSGPKRYDYVIIGDGQNQKEGTGLGDWVYLRDGSTLSGLLMEELNVDVITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRX6</accession>
    <name>G4MRX6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_02463</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709257.1">
        <property type="nucleotide sequence ID" value="XM_003709209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRX6"/>
    <dbReference type="SMR" id="G4MRX6"/>
    <dbReference type="FunCoup" id="G4MRX6">
        <property type="interactions" value="531"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRX6"/>
    <dbReference type="GeneID" id="2681560"/>
    <dbReference type="KEGG" id="mgr:MGG_02463"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02463"/>
    <dbReference type="eggNOG" id="KOG4392">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090381_2_1_1"/>
    <dbReference type="InParanoid" id="G4MRX6"/>
    <dbReference type="OMA" id="MNAPSRY"/>
    <dbReference type="OrthoDB" id="10248581at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06926">
        <property type="entry name" value="RNAP_II_RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037685">
        <property type="entry name" value="RBP11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF16">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="6">
        <location>
            <begin position="31"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA56645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="130" mass="14810" checksum="286963224B3B2B58" modified="2011-12-14" version="1">MNAPDRFELFLLEPGEEKLTETINTSMSNTSDFTFKKEDHTLGNMLTEHLKQHPNVLMAGYKVSHPNVPEFFLRIQTDGKVTPKACLLDACRTILHSLGQIRTEFTREFELRRMVAAGEQQQNGEHGHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSE1</accession>
    <name>G4MSE1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PWI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_04513</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713560.1">
        <property type="nucleotide sequence ID" value="XM_003713512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSE1"/>
    <dbReference type="SMR" id="G4MSE1"/>
    <dbReference type="STRING" id="242507.G4MSE1"/>
    <dbReference type="GeneID" id="2678083"/>
    <dbReference type="KEGG" id="mgr:MGG_04513"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04513"/>
    <dbReference type="eggNOG" id="KOG2146">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032410_4_1_1"/>
    <dbReference type="InParanoid" id="G4MSE1"/>
    <dbReference type="OMA" id="ETPGFCK"/>
    <dbReference type="OrthoDB" id="163257at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052225">
        <property type="entry name" value="Ser/Arg_repetitive_matrix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148">
        <property type="entry name" value="SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148:SF0">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWI" evidence="3">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="215"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="299"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="402" mass="43408" checksum="53A205C555B9CAEC" modified="2011-12-14" version="1">MFAPGTEKVDLGTRNDDYSHFGLFITWIASRISEILGSEDDVVIELCYNLIESSRFPDIKGLQIQLTGFLDKETPGFCKELWNLCLSAQASPQGVPKELLEAKKRELMQEKIEAEKAAEERQKREAQSFRGRGDGRSDSYRGGGRGRGRGGGFGDRDMNDRRGGFNRGRDGSRSPPPRGGAGGDSYRAPRRDIYVPRGRRNSMGRRGDTKRRSPSRSPSVDSGSSRSRTRSASSASSNRSPSRSRSPPPRPEAEAAAAAVAHLVARMANLAGAIRGEGDHQRAAQARRVHEVAVAGAGAMAPVAPAKTVAAAAPIGSDRKRRQSPSISPPRESRDKSADGSRTKDRPTPQPHTGDPDSTAAASSPSKARKVSVDKDATLLREKELKERILQMRSSKSGPSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSE7</accession>
    <name>G4MSE7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GID complex catalytic subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glucose-induced degradation protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_04518</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RMD5/GID2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713566.1">
        <property type="nucleotide sequence ID" value="XM_003713518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSE7"/>
    <dbReference type="FunCoup" id="G4MSE7">
        <property type="interactions" value="570"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSE7"/>
    <dbReference type="GeneID" id="2678036"/>
    <dbReference type="KEGG" id="mgr:MGG_04518"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04518"/>
    <dbReference type="eggNOG" id="KOG2817">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020227_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSE7"/>
    <dbReference type="OMA" id="LIRECKM"/>
    <dbReference type="OrthoDB" id="1933281at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16652">
        <property type="entry name" value="dRING_Rmd5p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000143">
        <property type="entry name" value="Regulator of gluconeogenesis Rmd5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037683">
        <property type="entry name" value="Rmd5_dRing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF3">
        <property type="entry name" value="GH10162P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CTLH" evidence="11">
        <location>
            <begin position="201"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="RING-Gid-type" evidence="12">
        <location>
            <begin position="381"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="9">
        <location>
            <begin position="381"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="144"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00075398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00080744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA53759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="436" mass="48068" checksum="ECE4776BC0EC2827" modified="2011-12-14" version="1">MSKTGVAIPQLQKDLEGMEDKPRLSLAVDNIDRLIAKLTEAREAVATASDPHTASLTLTRLQNPVKEVIDRANDDLKKVYQVQKDLGKSLDKSFPVVKIATDHDALDGKSDLMNKAIAMHLMREGQFSVASTFIGESQRDLHVASSTPQAFHGKTRDVQDSNTMAVDSDGDTDQQSQSSSKVPSQPNASSEVIGSSRLQQQFEVMYRILQELKQHNVEPAIEWALENSSELEARGSNLEFELCRLQYVHLFETPGRGPPAAFEYARTQMWRFRERHLAEITRLAGALIYAPNLADSPYATLFDSPTAFLDAASSFTREFCSLLGLSAESPLYVAATAGAIALPRLVKWQSIAQGAEWTTTNELAFETPLPRSFMYHSIFVCPVSKEQTTAANPPVILPCGHVLARDSLTNIAKGTRFKCPYCPSEGQVKDARVIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSS2</accession>
    <name>G4MSS2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LysM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_04532</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the secreted LysM effector family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713584.1">
        <property type="nucleotide sequence ID" value="XM_003713536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSS2"/>
    <dbReference type="STRING" id="242507.G4MSS2"/>
    <dbReference type="GeneID" id="2677828"/>
    <dbReference type="KEGG" id="mgr:MGG_04532"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04532"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010591_8_2_1"/>
    <dbReference type="InParanoid" id="G4MSS2"/>
    <dbReference type="OMA" id="NCNAFHT"/>
    <dbReference type="OrthoDB" id="2281372at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF2">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465466" evidence="5">
        <location>
            <begin position="28"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="44"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="170"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="272"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="6">
        <location>
            <begin position="447"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA53777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="494" mass="53768" checksum="03791433001C0451" modified="2011-12-14" version="1">MSTRQTTLASVVFGLLVFYPILVSSQAVPPPGPTQPGTAPNCNKWHIVISGSGDNCDNVAARYKITLAQFLKWNPAVSSDCLQFFWPDYAYCVSVDASITAVPTTSASVRTTFATRTTSAVSTSVLPPVSTPSYTFNHPVTDLNITTPTVPTEEWPPKNTQAGQPSYCNDWHLVMPGESCRAIVLQHGSWMGIEDFFLWNPAVGSDCMGLSLYKYVCVGIQPQTQISIDFPTVTNNATVPPMVIPTAVELPPVDNNFAPSPAQGPLPTDCVEYYLTQPGETCRDVVAKHDSITQAQFLAWHPFLNGNCDGLWLGYYYCILVENFIPEPPVETSAPSPVEAGIVSDCRAWFKATGPTWTCEQFVLIFGRFSLFDFIKWNPAVGSSCENSIKADYWYCVAVPDTPTTRTATLPGVTSTATVVPPTSTTASPPPATPTPTQPGMISGCRKFYFVQSGDGCWVIANSAGIELTDFYKWNPGVEECGKLWPEYYVCVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTV1</accession>
    <name>G4MTV1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ADP-ribosylation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01574</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714552.1">
        <property type="nucleotide sequence ID" value="XM_003714504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTV1"/>
    <dbReference type="SMR" id="G4MTV1"/>
    <dbReference type="STRING" id="242507.G4MTV1"/>
    <dbReference type="GeneID" id="2679520"/>
    <dbReference type="KEGG" id="mgr:MGG_01574"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01574"/>
    <dbReference type="eggNOG" id="KOG0075">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040729_10_3_1"/>
    <dbReference type="InParanoid" id="G4MTV1"/>
    <dbReference type="OMA" id="FRNMWER"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="PHI-base" id="PHI:9551"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04159">
        <property type="entry name" value="Arl10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001015">
        <property type="entry name" value="ADP-ribosylation factor-like protein 8B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044154">
        <property type="entry name" value="Arl8a/8b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732:SF7">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="183" mass="20555" checksum="B8A8AC514259AA0B" modified="2011-12-14" version="1">MAAIIKGLYDWLLRTFWATEMDVTMIGLQNAGKTSLLRVLSGGEFTIDTIPTVGFNMKKVQRGHVTMKCWDMGGQERFRGMWERYCRGVTAILFIVDVADFDQIPTAKQHLHSLMGCESLVGIPLLVLGNKSDLPDKLSVDELIDAMDLKSINTREVSCYGISAKEETNLDAVIQWLMKYSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU20</accession>
    <name>G4MU20_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycosyl transferase family 25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_07214</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 25 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715427.1">
        <property type="nucleotide sequence ID" value="XM_003715379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU20"/>
    <dbReference type="GeneID" id="2683102"/>
    <dbReference type="KEGG" id="mgr:MGG_07214"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07214"/>
    <dbReference type="eggNOG" id="KOG4179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032992_0_0_1"/>
    <dbReference type="InParanoid" id="G4MU20"/>
    <dbReference type="OMA" id="YDREDAM"/>
    <dbReference type="OrthoDB" id="47375at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06532">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050757">
        <property type="entry name" value="Collagen_mod_GT25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730:SF53">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730">
        <property type="entry name" value="PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 25" evidence="7">
        <location>
            <begin position="141"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA55620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="459" mass="52776" checksum="C538A8023851B62E" modified="2011-12-14" version="1">MINKYAMRNMFSTRRSTGIFVVSAWVVFAFLFYVFIYVHNQESLITSIVRKLDKAGTEAQAHAERQKALQQKKEDAEEQLRLAASNSTLGLHSIQFLNLPHRHDRFDAAAIQSLLSDIDVEYFPAVVDTDIRDQGLPPTSKPNTLKKGEIGCWRAHANLWQYQVQKRIPALLILESDAAWDVYIRQQMGVLNKPFRELLVQDNPDILRQPAHNKSSSAADQNTRGRTHAKDLADDYEDYDDLAAKRAALENQYVDPLPVDPEDPWAAKTGLWDILTIGHCFDSRDKTSTSFRVYDDPWGPNNGFQFNDIGMDKPLNRQRVVFRAMGMVCTTGYIISLRGAAKLLVRTNFNLDMPVDLIMNEMAKAGELTIYSVQQRMVVQWIYRNGLGMKERGAQSDIHNEKAEGKWDMSGWDDAWKTKDVYDYKWSYENSGFENFALKKAWGVTMNDWDMTRRDVMRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU25</accession>
    <name>G4MU25_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715432.1">
        <property type="nucleotide sequence ID" value="XM_003715384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU25"/>
    <dbReference type="GeneID" id="12986676"/>
    <dbReference type="KEGG" id="mgr:MGG_15881"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15881"/>
    <dbReference type="HOGENOM" id="CLU_2996924_0_0_1"/>
    <dbReference type="InParanoid" id="G4MU25"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="57" mass="6511" checksum="692D7B851A422679" modified="2011-12-14" version="1">MYSVHRYKKFNKLENCGPAQALRSQAERPGKLKHESVGRGTDERQDQLGLVRGWAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUJ7</accession>
    <name>G4MUJ7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">UDP-N-acetylglucosamine transferase subunit ALG13</fullName>
            <ecNumber evidence="2 7">2.4.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Asparagine-linked glycosylation protein 13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ALG13</name>
        <name evidence="10" type="ORF">MGG_07272</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 7">Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UDP-N-acetyl-alpha-D-glucosamine = an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23380"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19510"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57269"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.4.1.141"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1 7">Heterodimer with ALG14 to form a functional enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.141" evidence="2 7"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715496.1">
        <property type="nucleotide sequence ID" value="XM_003715448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUJ7"/>
    <dbReference type="SMR" id="G4MUJ7"/>
    <dbReference type="STRING" id="242507.G4MUJ7"/>
    <dbReference type="GeneID" id="2683018"/>
    <dbReference type="KEGG" id="mgr:MGG_07272"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07272"/>
    <dbReference type="eggNOG" id="KOG3349">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078324_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUJ7"/>
    <dbReference type="OMA" id="QYKFRPN"/>
    <dbReference type="OrthoDB" id="20273at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043541">
        <property type="term" value="C:UDP-N-acetylglucosamine transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052474">
        <property type="entry name" value="UDP-GlcNAc_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47043">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47043:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 28 C-terminal" evidence="9">
        <location>
            <begin position="22"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="219"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="250" mass="27055" checksum="E6FC2270F80BDD36" modified="2011-12-14" version="1">MNIDTSPPAAEAAHSHLPRRAFVTIGATAGFRSLLEQVLRPEFLRWMRGYGFVRMTVQCGSDLEWFRSSLAAVADTCGVEVDCFQYTTSMRDYIMPCRPVEGVCNAGIVICHAGAGTVVDVSRCGVPFVVVPNEGLMDNHQAELATHLDKERWAVAAKPEALPQAIRRAHEQAYAGGLAPQPEVSAGVSEDAGFPAPEHERITLLDWMTLSCYDDASSSTLATLGQPSASDMSSENKSRSARHPHARPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV96</accession>
    <name>G4MV96_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Methylenetetrahydrofolate reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_01728</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714725.1">
        <property type="nucleotide sequence ID" value="XM_003714677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV96"/>
    <dbReference type="SMR" id="G4MV96"/>
    <dbReference type="FunCoup" id="G4MV96">
        <property type="interactions" value="419"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MV96"/>
    <dbReference type="GeneID" id="2679748"/>
    <dbReference type="KEGG" id="mgr:MGG_01728"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01728"/>
    <dbReference type="eggNOG" id="KOG0564">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025841_2_2_1"/>
    <dbReference type="InParanoid" id="G4MV96"/>
    <dbReference type="OMA" id="AWKEEFY"/>
    <dbReference type="OrthoDB" id="16284at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="PHI-base" id="PHI:3823"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.220:FF:000002">
        <property type="entry name" value="Methylenetetrahydrofolate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004621">
        <property type="entry name" value="Fadh2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00677">
        <property type="entry name" value="fadh2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="10">
        <location>
            <begin position="303"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="612"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="617"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA54918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="631" mass="71367" checksum="704107E8C960510D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVH5</accession>
    <name>G4MVH5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Spherulin-4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715608.1">
        <property type="nucleotide sequence ID" value="XM_003715560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVH5"/>
    <dbReference type="SMR" id="G4MVH5"/>
    <dbReference type="GeneID" id="2683086"/>
    <dbReference type="KEGG" id="mgr:MGG_07367"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07367"/>
    <dbReference type="eggNOG" id="ENOG502T62S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060605_3_0_1"/>
    <dbReference type="InParanoid" id="G4MVH5"/>
    <dbReference type="OMA" id="PLYAWPG"/>
    <dbReference type="OrthoDB" id="5342184at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021986">
        <property type="entry name" value="Spherulin4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35040:SF9">
        <property type="entry name" value="4-LIKE CELL SURFACE PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14080)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12138">
        <property type="entry name" value="Spherulin4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465671" description="Spherulin-4" evidence="1">
        <location>
            <begin position="18"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="29541" checksum="7B47E17C540D4734" modified="2011-12-14" version="1">MLAIKSLLLLHATAAAALDILVPLYIYPSTVWNDNASEWQSLLSTVRAHRAVTFDVIVNADSGPGADLADVNYAAGITLLNAETNVRTVAYVHCDYGRIATDAVMANATRWRSIGGGAGLDGIFFDETPNVHDWASVCSEQAGCSAAEYMAHLARRTRAAGFGRLVYNVGQQVAPANEAAYLRDADQIIAFEQSWEAYKATQPLVAGLPGSGAGAAGKSNIMVHHFDGTLGELEAEVRRIAAEPRVGSVWFTTVEYQTYDTPPASVENLARIIEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVN0</accession>
    <name>G4MVN0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_08917</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713946.1">
        <property type="nucleotide sequence ID" value="XM_003713898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVN0"/>
    <dbReference type="SMR" id="G4MVN0"/>
    <dbReference type="STRING" id="242507.G4MVN0"/>
    <dbReference type="GeneID" id="2679903"/>
    <dbReference type="KEGG" id="mgr:MGG_08917"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08917"/>
    <dbReference type="eggNOG" id="ENOG502RF8N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015502_0_1_1"/>
    <dbReference type="InParanoid" id="G4MVN0"/>
    <dbReference type="OMA" id="WDLFIID"/>
    <dbReference type="OrthoDB" id="5367487at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47431">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="61"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="14"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="99"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA54139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="648" mass="70545" checksum="7D310A3ED441BBE1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW10</accession>
    <name>G4MW10_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713970.1">
        <property type="nucleotide sequence ID" value="XM_003713922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW10"/>
    <dbReference type="GeneID" id="12987319"/>
    <dbReference type="KEGG" id="mgr:MGG_15611"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15611"/>
    <dbReference type="HOGENOM" id="CLU_2671540_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW10"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="75" mass="8454" checksum="41F5AF287DE0BF7C" modified="2011-12-14" version="1">MYMCTVGYLYRFSRSVSSCESSLCSAKQLEHNKGTKKTFSPHSDGLQRHPSGGRLASEAECPHSYWNRLVKHMTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWV0</accession>
    <name>G4MWV0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715761.1">
        <property type="nucleotide sequence ID" value="XM_003715713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWV0"/>
    <dbReference type="SMR" id="G4MWV0"/>
    <dbReference type="GeneID" id="12986772"/>
    <dbReference type="KEGG" id="mgr:MGG_15952"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15952"/>
    <dbReference type="HOGENOM" id="CLU_2061970_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWV0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="119" mass="13633" checksum="939B3D003FEB1F2C" modified="2011-12-14" version="1">MSILTWRQFVNFVSPKFLSNTRLEEYNVNCTLHINNYPYATATMEGEDGFRGATVKRRLEIAAPFRGQLMSDGHGTRCVSRLMTRNQARVQKQKEEQKKKESPNLHLRTAGKAIKSNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX55</accession>
    <name>G4MX55_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
            <ecNumber evidence="3 14">2.4.1.258</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Dol-P-Man-dependent alpha(1-3)-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_08010</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 14">Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the first dolichyl beta-D-mannosyl phosphate derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-dolichol to produce Man(6)GlcNAc(2)-PP-dolichol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29527"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="Rhea" id="RHEA-COMP:19517"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="ChEBI" id="CHEBI:132516"/>
            <dbReference type="EC" id="2.4.1.258"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12 14">
            <dbReference type="Rhea" id="RHEA:29528"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the glycosyltransferase ALG3 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.258" evidence="3 14"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714960.1">
        <property type="nucleotide sequence ID" value="XM_003714912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX55"/>
    <dbReference type="FunCoup" id="G4MX55">
        <property type="interactions" value="645"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MX55"/>
    <dbReference type="GeneID" id="2678276"/>
    <dbReference type="KEGG" id="mgr:MGG_08010"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08010"/>
    <dbReference type="eggNOG" id="KOG2762">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035382_3_0_1"/>
    <dbReference type="InParanoid" id="G4MX55"/>
    <dbReference type="OMA" id="PERYGIH"/>
    <dbReference type="OrthoDB" id="20028at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052925">
        <property type="term" value="F:dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007873">
        <property type="entry name" value="Glycosyltransferase_ALG3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646:SF0">
        <property type="entry name" value="DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646">
        <property type="entry name" value="NOT56 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05208">
        <property type="entry name" value="ALG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU364047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA55153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="432" mass="48235" checksum="2FF4899D75DC0341" modified="2011-12-14" version="1">MAAERPSTLGKPVQFVFDVANGRHPLSRAIPPMLLAFDGLLCGLIIKKVPYTEIDWTTYMQQIKQYVTGERDYTKITGSTGPLVYPAGHVYIYTGLYHITDEGRNILFAQQLFGALYLLTLYVVIACYRKAKVPPYVLPLLVLSKRLHSIFVLRCFNDCFAVLFFWLAIYCFQRRAWSLGGVFYSFGLGIKMTVLLSLPAVGVILLLGRGFGGALNVASIMGQLQVAIGLPFLSKNAWGYLSRAFELSRQFMFKWTVNWRFVGEETFLSKPFAITLLALHASVLLAFVTKRWLKPASKSIGGLIAPLLSGRPIFTAEEAQTAARAVTPEYVMTTMLTANIVGMLFARSLHYQFYAYLAWSTPYLLWRSGIHPLLQWGLWALQEWAWNVYPSTPVSSGVVVGVMAITVGAVMVGAKAEFRPQVPVAKKVEAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY50</accession>
    <name>G4MY50_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA54381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003714140.1"/>
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        <property type="entry name" value="WH2"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="433"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA54381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="466" mass="45596" checksum="28045E03AA844944" modified="2011-12-14" version="1">MPPPPPPPPPPPMPGRGGPPPPPPPPGGLPARPPAGNNRGALLSDITKGKALKKTVTNDRSAPILAGSGGGTSAAPPVGGAPPVPGMLGGMPKPPGGLAPPVPGNRMRSNSDHGRSDSTGSAGGLETSAPQLGGLFAGGMPKLRKTGGGVDTGANRDASYLSDPENSAGSAPKPPSMSAPKPPSGAAPRVPGRPGVPAPQVGPTSHPSIANLRKNPSDVQRPFSSASMMKGPPPPIGKKPPPPPGSRKPSSIAVAPPAPPSAPPAPPPPPPSAAPRPPPAPSRGTPPPPAVPPSSGPSSNGAAAASLAVQAAIRAASSPSSAPAAPPPPPPPPVSRGNSNPTSPPPPPPSSGAPPPPSSPVPPPPRPAQHQQQPSASRAALLDPAAFTLTPNGGKLHSPTRSLSGARPGTAGGDGANGGGMYVVHDPRWKFVGEDKFPKPREFSGGAKRYRAGRGSSVPLDLRSLG</sequence>
</entry>
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    <accession>G4MYF0</accession>
    <name>G4MYF0_PYRO7</name>
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        <submittedName>
            <fullName evidence="4">Secreted glucosidase</fullName>
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        <name evidence="4" type="ORF">MGG_10475</name>
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            <taxon>Sordariomycetes</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53570.1"/>
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        <property type="nucleotide sequence ID" value="XM_003713329.1"/>
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        <property type="family name" value="Glycoside Hydrolase Family 16"/>
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    <dbReference type="KEGG" id="mgr:MGG_10475"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10475"/>
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        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02182">
        <property type="entry name" value="GH16_Strep_laminarinase_like"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
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        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
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    <proteinExistence type="predicted"/>
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        <location>
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        </location>
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        </location>
    </feature>
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    </feature>
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    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA53570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="476" mass="48741" checksum="71E8D9A9906693D5" modified="2011-12-14" version="1">MRTAQALSVFALLVGSGLATPVPASGAYYDGASSMLQPVSAAADFDDADDTAMPASAAFSAANTRSAIAAAADEDDDADTRMPVSAASSAANTRTAFAAAADEDDANDADDTAIPVSRAFSAASTRTAFAAAADEDDTEDSADSADTADTAMPVSAASVGTQGLRGNSRAAAAADDLAAAATNSSESPLAAAAGDIAIPQGFKKIVFQDNFAKQKAGALPDQAKWLIDLGTQYPGGAANWGTQEIQTYTNNPANLGIKNGALTITPVRNGNAWTSARIETKAGSDVQCPPGGKLRVEASLKLAASDPATQLGIWPAFWMLGQGFRTDRNSWPKVAEIDILEVSNGVGTVFHTAHCGVINGGPCKEKTGLGGSGQFPRGKFVKVAVTIDRSNKAGGFQQEKLEWSVDGKVTHTLTGAEVKDADAWENLARTPKMILLNVAIGGEFPDGKAKIKTPTAKTVGGEPSAMSVQYVAAFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYG3</accession>
    <name>G4MYG3_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">MGG_10486</name>
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    <organism evidence="2 3">
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
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                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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</entry>
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            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    </reference>
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        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
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                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714246.1">
        <property type="nucleotide sequence ID" value="XM_003714198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYL4"/>
    <dbReference type="SMR" id="G4MYL4"/>
    <dbReference type="FunCoup" id="G4MYL4">
        <property type="interactions" value="68"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYL4"/>
    <dbReference type="GeneID" id="12984624"/>
    <dbReference type="KEGG" id="mgr:MGG_15672"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15672"/>
    <dbReference type="eggNOG" id="KOG1637">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008554_2_0_1"/>
    <dbReference type="InParanoid" id="G4MYL4"/>
    <dbReference type="OMA" id="SCKGHPL"/>
    <dbReference type="OrthoDB" id="5423599at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070159">
        <property type="term" value="P:mitochondrial threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000039">
        <property type="entry name" value="Threonyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF50">
        <property type="entry name" value="THREONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="88"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA54439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="503" mass="55811" checksum="62DDDC9FB5DF3CD3" modified="2011-12-14" version="1">MLPLRASRIPVLALARPGHQRILLPCLSQRLGTIRSCASHTPTPVPASSTPTPSAGADQAAPDHRTLGVRQELFTTSIYSPGSPIFLPNGTRIFNRLVEFLRKQYVRYGFQEVLTPTIYKKALWAKSGHLENYSDDMYTVTSTSPSRADSTGDAEADEYGLKPMNCPGHCLIFASQLRSYRDLPIRYADFSPLHRNEVSGALSGLTRVRRFHQDDGHIFCRPSQIEEEIRQTLSFVKTTYDTLKLGPYRLVLSTRPEDHYIGELAEWDQAETALKAALDSLGERWTLNPGDGAFYGPKIDIILQDSDGKEHQTATVQLDFQLPKRFELEYQAPPPENGDANATALLERPVMIHRAVLGSVERLMALLIEHYNGKWPFWLNPRQVMVVTVNDTARVVAKAFAVRNQLLGQEEGEVAASSQLAIDIDDSARSLPLKIREAKSKGYGAIVTVGNHEVDCDILPIDMSAMPDVALPDGTSSKSHKRPVKLDIASISKLLRGSVEAYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYQ1</accession>
    <name>G4MYQ1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">laccase</fullName>
            <ecNumber evidence="4">1.10.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_08127</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11276"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17594"/>
            <dbReference type="ChEBI" id="CHEBI:17977"/>
            <dbReference type="EC" id="1.10.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.2" evidence="4"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715087.1">
        <property type="nucleotide sequence ID" value="XM_003715039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYQ1"/>
    <dbReference type="SMR" id="G4MYQ1"/>
    <dbReference type="STRING" id="242507.G4MYQ1"/>
    <dbReference type="GeneID" id="2678322"/>
    <dbReference type="KEGG" id="mgr:MGG_08127"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08127"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_3_2_1"/>
    <dbReference type="InParanoid" id="G4MYQ1"/>
    <dbReference type="OMA" id="CHIIEHQ"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052716">
        <property type="term" value="F:hydroquinone:oxygen oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046274">
        <property type="term" value="P:lignin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13880">
        <property type="entry name" value="CuRO_2_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000021">
        <property type="entry name" value="Extracellular dihydrogeodin oxidase/laccase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000045">
        <property type="entry name" value="Laccase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000046">
        <property type="entry name" value="Multicopper oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF87">
        <property type="entry name" value="LACCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465516" description="laccase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="15">
        <location>
            <begin position="115"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="13">
        <location>
            <begin position="227"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="14">
        <location>
            <begin position="442"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA55280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="604" mass="66424" checksum="4EE495CBBCFA111C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYX2</accession>
    <name>G4MYX2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Large ribosomal subunit protein bL21m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713440.1">
        <property type="nucleotide sequence ID" value="XM_003713392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYX2"/>
    <dbReference type="SMR" id="G4MYX2"/>
    <dbReference type="FunCoup" id="G4MYX2">
        <property type="interactions" value="180"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYX2"/>
    <dbReference type="GeneID" id="2676340"/>
    <dbReference type="KEGG" id="mgr:MGG_10825"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10825"/>
    <dbReference type="eggNOG" id="KOG0453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061463_0_1_1"/>
    <dbReference type="InParanoid" id="G4MYX2"/>
    <dbReference type="OMA" id="FAPFRHI"/>
    <dbReference type="OrthoDB" id="5994at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="bL21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="bL21-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="L21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="50"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="236" mass="25461" checksum="BCE8EF6616350DDF" modified="2011-12-14" version="1">MNNTLLRCLGGLRSSVPRLAAPATSTLAPAASRLRLQHANWFNTSAPVAEQPSLAKAQQSNSSDATISASSLPPKPQTATDPSAAPQTALSSIPDLLPLLAAQPKHYITVHIHGKPYLVTPGDSVRLPFKMPGVLPGDTLRLDRATTIGSRDFTLQGKPYVSTDLFRCRATVIGTDSEPIRLKVVKKQRTRRAKTIKSKHFYTTIRISELKIVLPEEPAPKPVSAPGYSDTGIVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ11</accession>
    <name>G4MZ11_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6546 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714285.1">
        <property type="nucleotide sequence ID" value="XM_003714237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ11"/>
    <dbReference type="GeneID" id="2679729"/>
    <dbReference type="KEGG" id="mgr:MGG_01356"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01356"/>
    <dbReference type="eggNOG" id="ENOG502R76C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_571160_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ11"/>
    <dbReference type="OMA" id="VINCHVE"/>
    <dbReference type="OrthoDB" id="5333491at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046676">
        <property type="entry name" value="DUF6546"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20183">
        <property type="entry name" value="DUF6546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6546" evidence="1">
        <location>
            <begin position="275"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="478" mass="55172" checksum="411B525A677F3E6E" modified="2011-12-14" version="1">MRELRFSKDELITFEQLFLDVRRRRYIRYIGLEFLFIDSVESVDNSVWTASICDRNLARLHRELNRQTTNAEDNAAWNTKRINYEVTNMIYWFISLTSRWERSEVSHDGICLELIAETKSYCQELACRFVEYDGDVLDNSYLNTIDEDYRAFLYRSASRDFDRQAEWDHTWQVDLDALGLPCNTFESLTADFISGISLNYDNVRYISPYVVNKLAKQLSSIEYIDWQYKARFCSTEKHDKLIDDHIAAVAQLPATIRSLCLRQVGLGQFWGAQGNQQTYESHKRGDLAAALAALAARQLEKLTVTCVIDALDFFKMAGPNTMWPMLKHLALTTSCLDDKEPTSFESPRAHQIQRVIHKAGEAALRMPQLDFFSLTNGNPDGGVDVFFSFQVHEYEPHEFEPSFAMVKVFADQRNEHATNDVLTRLSLKKWHEVAASRSLDLTMKVGFGGDTEQHWHWSLMGGMAGVDRLQYPVVRQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZR2</accession>
    <name>G4MZR2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07054</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715233.1">
        <property type="nucleotide sequence ID" value="XM_003715185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZR2"/>
    <dbReference type="GeneID" id="2682939"/>
    <dbReference type="KEGG" id="mgr:MGG_07054"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07054"/>
    <dbReference type="eggNOG" id="ENOG502SHVM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_7_1"/>
    <dbReference type="InParanoid" id="G4MZR2"/>
    <dbReference type="OMA" id="YARTWIR"/>
    <dbReference type="OrthoDB" id="5331848at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="32"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="374" mass="41628" checksum="7A649D4523BB775E" modified="2011-12-14" version="1">MDHSIVPQENRGPAFLVITGTLTSIATLFVGARLYTRAVIKRLVFCEDYIVILATLLLWVQLCTYTVAVQNGVGRHLRALTPEEREVALMWYHLAPFPSVIALGVPKIALAMMLNRVLLASFWASAASWFLSATSMANFVVTSLLIAFQCSPIRAAWIPDIADAKCTSERVIVWFSIYTSAFSALADIYLALWPAFIIFKVETNKPKSIALSIVLGLGVLASGVAVYKMTLMKALESADRTYDGIDLLIWTLAEAAATLIASSIPMITPIYILMAQWMRGTKPRERDRDRDREGDSAAEYIQRMAQERLFQHRSTDQEAGIFHRPSFRRQHSNRLWSPSRVGNVRGDKIGVSMAMNSNRDGSGPSHGSLETDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZY5</accession>
    <name>G4MZY5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytosolic Fe-S cluster assembly factor NBP35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NBP35</name>
        <name evidence="12" type="ORF">MGG_06151</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712030.1">
        <property type="nucleotide sequence ID" value="XM_003711982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZY5"/>
    <dbReference type="SMR" id="G4MZY5"/>
    <dbReference type="FunCoup" id="G4MZY5">
        <property type="interactions" value="591"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZY5"/>
    <dbReference type="GeneID" id="2684339"/>
    <dbReference type="KEGG" id="mgr:MGG_06151"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06151"/>
    <dbReference type="eggNOG" id="KOG3022">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024839_0_1_1"/>
    <dbReference type="InParanoid" id="G4MZY5"/>
    <dbReference type="OMA" id="VSGCPMR"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904564">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly scaffold complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000427">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03038">
        <property type="entry name" value="NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028601">
        <property type="entry name" value="NUBP1/Nbp35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF35">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
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        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="86"/>
            <end position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA52223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="343" mass="36474" checksum="DCC2A1B9300915B3" modified="2011-12-14" version="1">MAPSLEEPEAVQEVINNPLKAKPQLVAPEPEHCPGPESERAGTADSCAGCPNQKICASAPKGPDPDIPLISARLAGVKHKILVLSGKGGVGKSTFTSLLAHAFATNPESSVGIMDTDICGPSIPKMMGAEAETIHISGAGWSPVYVMDNLGVMSIQFMLPNRDDAIIWRGPKKNGLIKQFLKDVEWGDLDFLLVDTPPGTSDEHLSVNTYLRESGIDGAVVVTTPQEVSLLDVRKEIDFCHKAGIRVLGLVENMSGFVCPGCKHTSQIFRPTTGGGRALAKEMGIRFLGSVPLDPSIGMACDYGESFFDSFPDSPTCASVENVVRELAEELGLAVDNVLPPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N004</accession>
    <name>G4N004_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712049.1">
        <property type="nucleotide sequence ID" value="XM_003712001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N004"/>
    <dbReference type="GeneID" id="2684322"/>
    <dbReference type="KEGG" id="mgr:MGG_06168"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06168"/>
    <dbReference type="eggNOG" id="ENOG502T24R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027362_1_0_1"/>
    <dbReference type="InParanoid" id="G4N004"/>
    <dbReference type="OMA" id="NQGFYQV"/>
    <dbReference type="OrthoDB" id="3595619at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465562" evidence="2">
        <location>
            <begin position="26"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="102"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="174"/>
            <end position="234"/>
        </location>
    </feature>
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        <location>
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            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
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            <end position="199"/>
        </location>
    </feature>
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            <end position="386"/>
        </location>
    </feature>
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            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="493" mass="54328" checksum="0998243AF76083E2" modified="2011-12-14" version="1">MSALGLVLFEAYSLWLKSISSCASCAPSMIPCLDRQKAARHEVEKADFVIYSDQPGFIPPPSLGRLASTTEAEPLVERPASAARRAGRRVFSVQKRFLSRGSSSARRPRISAPTNFQHISSGSLQFPPPSRPRQRPRSFRPLELSIHSVNNYLLSPMLPHFEQEDREPCITAPQPAHIRDSFDSDTSTLTYQESTTSSLFHIPRRPLPQRPVSPGDSNGSPPRVPSRSRLRATLTSPERVEMMVERIASAMIEKETLQSDIDSVVQRQSIYAGRASLSAPGVEKIAPMPSIPATPAAAPSFAQRLSLDRPHTAPQKAVAIEVSTITAPPAFDISQLSMTQARFISQSTHELLGRPIGHSLPLVFRPPLRKKKSFTNISTWLSPNDSGEQDRDRGSSFESATNERTLTMENNDYYTYVAAPPARRASIVTVSSMSSWSAEEEQSYATTLSPPSTSPVRSRPGASTTPRTSRMFTFGRLSINGRQHWPHNVGVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>G4N054</accession>
    <name>G4N054_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="7">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_05332</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
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        </reaction>
    </comment>
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    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003712848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N054"/>
    <dbReference type="SMR" id="G4N054"/>
    <dbReference type="STRING" id="242507.G4N054"/>
    <dbReference type="GeneID" id="2675740"/>
    <dbReference type="KEGG" id="mgr:MGG_05332"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05332"/>
    <dbReference type="eggNOG" id="KOG0169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1265">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002738_3_0_1"/>
    <dbReference type="InParanoid" id="G4N054"/>
    <dbReference type="OMA" id="NCQLHVE"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="PHI-base" id="PHI:2018"/>
    <dbReference type="PHI-base" id="PHI:2106"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000220">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000039">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Shea T."/>
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                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    </reference>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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            <dbReference type="PubMed" id="15846337"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
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                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
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                <person name="Montmayeur A."/>
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                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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            <begin position="38"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="570" mass="62016" checksum="D33BBAC0CE8A647C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2V0</accession>
    <name>G4N2V0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_13926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713206.1">
        <property type="nucleotide sequence ID" value="XM_003713158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2V0"/>
    <dbReference type="STRING" id="242507.G4N2V0"/>
    <dbReference type="GeneID" id="5049421"/>
    <dbReference type="KEGG" id="mgr:MGG_13926"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13926"/>
    <dbReference type="eggNOG" id="ENOG502SM9E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022448_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2V0"/>
    <dbReference type="OMA" id="MGALEHV"/>
    <dbReference type="OrthoDB" id="5313079at2759"/>
    <dbReference type="PHI-base" id="PHI:2199"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="599" mass="67294" checksum="83CD3288B4E7D8A6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2Z5</accession>
    <name>G4N2Z5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome b2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_13441</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome b5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711561.1">
        <property type="nucleotide sequence ID" value="XM_003711513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2Z5"/>
    <dbReference type="SMR" id="G4N2Z5"/>
    <dbReference type="STRING" id="242507.G4N2Z5"/>
    <dbReference type="GeneID" id="5050365"/>
    <dbReference type="KEGG" id="mgr:MGG_13441"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13441"/>
    <dbReference type="eggNOG" id="KOG0537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0538">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_1_1_1"/>
    <dbReference type="InParanoid" id="G4N2Z5"/>
    <dbReference type="OMA" id="IEMNMVF"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02922">
        <property type="entry name" value="FCB2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037458">
        <property type="entry name" value="L-MDH/L-LDH_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF104">
        <property type="entry name" value="CYTOCHROME B2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="7">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="8">
        <location>
            <begin position="108"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA51754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="477" mass="52281" checksum="25BCC515273783F5" modified="2011-12-14" version="1">MDDYIDAAELSRHNSKSSCWIVIHGQVWDVTEFLELHPGGARIILKSAGRDATSSYESVHDPDLVTKTLAPSCLVGTINPQSTTLVPTAEEVPSPATDDSRSAQPIHPPLTSMLNVSDFERAAKKYLSDIGWAYYSSGAEDEISMQDPRRIFNRIALRPRILRHVETIDTSCSYFGGRIKSSLPIYITPTGLSRYAHQDGDQCLARACGHEGIVYCMPTTAAHEAVFGARTTPNQPLCFQLYTGRDYDRTRALLRKVERLGAAAIFVTVDSPVIGRRERDDRIKAADGEDPLFAAGVAKSGSMTLLNPTLTWDDLDWLRAATSLPLVLKGVQTVEDAVLAHRAGVDGIVLSNHGGRSQDTAQAPMLTLLEIRRHAPHLLAPETRSRFEVFLDGGVRRGTDVLKALALGASAVGVGRPALYSMTNGWGEAGVRRLIMMLRMEIETNMALAGATRLGEVVPEMVNTERVEHEVFRRVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N339</accession>
    <name>G4N339_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chromosome segregation protein BIR1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_04912</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712402.1">
        <property type="nucleotide sequence ID" value="XM_003712354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N339"/>
    <dbReference type="SMR" id="G4N339"/>
    <dbReference type="STRING" id="242507.G4N339"/>
    <dbReference type="GeneID" id="2675417"/>
    <dbReference type="KEGG" id="mgr:MGG_04912"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04912"/>
    <dbReference type="eggNOG" id="KOG1101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010318_1_0_1"/>
    <dbReference type="InParanoid" id="G4N339"/>
    <dbReference type="OMA" id="DEHYNRS"/>
    <dbReference type="OrthoDB" id="2196114at2759"/>
    <dbReference type="PHI-base" id="PHI:9259"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00022">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1170.10">
        <property type="entry name" value="Inhibitor Of Apoptosis Protein (2mihbC-IAP-1), Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051190">
        <property type="entry name" value="Baculoviral_IAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001370">
        <property type="entry name" value="BIR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46771">
        <property type="entry name" value="DETERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46771:SF5">
        <property type="entry name" value="DETERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00653">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00238">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57924">
        <property type="entry name" value="Inhibitor of apoptosis (IAP) repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50143">
        <property type="entry name" value="BIR_REPEAT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="259"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="379"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="517"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="578"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="602"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="613"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="634"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="710"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="881" mass="95498" checksum="F2AE10D79AB814BB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3B9</accession>
    <name>G4N3B9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 19">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4 19">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">MGG_13447</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 27">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 27">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 22">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 19"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711604.1">
        <property type="nucleotide sequence ID" value="XM_003711556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3B9"/>
    <dbReference type="SMR" id="G4N3B9"/>
    <dbReference type="FunCoup" id="G4N3B9">
        <property type="interactions" value="954"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N3B9"/>
    <dbReference type="GeneID" id="5050370"/>
    <dbReference type="KEGG" id="mgr:MGG_13447"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13447"/>
    <dbReference type="eggNOG" id="KOG2270">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018693_4_0_1"/>
    <dbReference type="InParanoid" id="G4N3B9"/>
    <dbReference type="OMA" id="HPMSLDF"/>
    <dbReference type="OrthoDB" id="205248at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
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        <property type="term" value="F:protein serine/threonine kinase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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    </dbReference>
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            <end position="389"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="109"/>
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            <begin position="472"/>
            <end position="558"/>
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            <begin position="18"/>
            <end position="45"/>
        </location>
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            <begin position="52"/>
            <end position="72"/>
        </location>
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        <location>
            <begin position="78"/>
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        </location>
    </feature>
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        <location>
            <begin position="484"/>
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        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
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            <begin position="505"/>
            <end position="534"/>
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        <location>
            <begin position="535"/>
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    </feature>
    <feature type="active site" description="Proton acceptor" evidence="20">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="20">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="275"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00009196"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA51797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="558" mass="63153" checksum="48562F8BC5B02C10" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3H1</accession>
    <name>G4N3H1_PYRO7</name>
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        <submittedName>
            <fullName evidence="5">Ubiquitin carboxyl-terminal hydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_04957</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
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        <property type="component" value="Chromosome 3"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Papain-like_cys_pep_sf"/>
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        <property type="entry name" value="Peptidase_C19_UCH"/>
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        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="513"/>
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    </feature>
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        <location>
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            <end position="1032"/>
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    </feature>
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        <location>
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    </feature>
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        <location>
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            <end position="21"/>
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    </feature>
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            <end position="186"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="336"/>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50206"/>
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    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA52646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1036" mass="113726" checksum="D7C673621934979E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3J7</accession>
    <name>G4N3J7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial cytochrome c oxidase assembly factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_04980</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PET100 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712479.1">
        <property type="nucleotide sequence ID" value="XM_003712431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3J7"/>
    <dbReference type="SMR" id="G4N3J7"/>
    <dbReference type="FunCoup" id="G4N3J7">
        <property type="interactions" value="16"/>
    </dbReference>
    <dbReference type="GeneID" id="2675547"/>
    <dbReference type="KEGG" id="mgr:MGG_04980"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04980"/>
    <dbReference type="eggNOG" id="ENOG502S1QV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156745_2_1_1"/>
    <dbReference type="InParanoid" id="G4N3J7"/>
    <dbReference type="OMA" id="VIFPIGW"/>
    <dbReference type="OrthoDB" id="18175at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018625">
        <property type="entry name" value="Pet100"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33968">
        <property type="entry name" value="PROTEIN PET100 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33968:SF1">
        <property type="entry name" value="PROTEIN PET100 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09803">
        <property type="entry name" value="Pet100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="94" mass="11179" checksum="B2CCF68167CB221C" modified="2011-12-14" version="1">MGRLNLEVFKFGMYVMFPIGVMFYFGTNLDNRFTVNDFWPKPEQTNKVPTDRDEIRAELERLRTQRLLNRDRRLAAEAAEARLRPQAPEESRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N490</accession>
    <name>G4N490_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711765.1">
        <property type="nucleotide sequence ID" value="XM_003711717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N490"/>
    <dbReference type="GeneID" id="12984203"/>
    <dbReference type="KEGG" id="mgr:MGG_16718"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16718"/>
    <dbReference type="HOGENOM" id="CLU_458600_0_0_1"/>
    <dbReference type="InParanoid" id="G4N490"/>
    <dbReference type="OMA" id="NSCCHER"/>
    <dbReference type="OrthoDB" id="5244867at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466100" evidence="2">
        <location>
            <begin position="21"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="595" mass="51119" checksum="20A34D2D21FB9D23" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4B5</accession>
    <name>G4N4B5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711790.1">
        <property type="nucleotide sequence ID" value="XM_003711742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4B5"/>
    <dbReference type="GeneID" id="12984209"/>
    <dbReference type="KEGG" id="mgr:MGG_16720"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16720"/>
    <dbReference type="eggNOG" id="ENOG502RJVF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1272535_0_0_1"/>
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    <dbReference type="OMA" id="WRIWIDG"/>
    <dbReference type="OrthoDB" id="5196653at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="145"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="244" mass="27485" checksum="8DF44E00C3F448F7" modified="2011-12-14" version="1">MSLSPVTVSRPPHSGRWPRTARLVWREREETSDDGEALLVWDEVWTRPSRKFGRSKEGRLRQVAEIPALAPHFPRLLKANRINGVLTLARPAYRRRALLSELDAATLRRLKADLKAVFSALYDHAIAYVFTPDGFEVVSRCRPWERRPSSSSESESGESTCTEASGETEDGTAAAAAAAVAPAEWSIYIDGWNHATRHKVRDPGSKKTAYFSEMEAEQLQRIDEYFAPFETRAKTSIFALLNHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4G1</accession>
    <name>G4N4G1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712636.1">
        <property type="nucleotide sequence ID" value="XM_003712588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4G1"/>
    <dbReference type="GeneID" id="12985142"/>
    <dbReference type="KEGG" id="mgr:MGG_16872"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16872"/>
    <dbReference type="HOGENOM" id="CLU_2264274_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4G1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="103" mass="11264" checksum="D5373F90D27B9586" modified="2011-12-14" version="1">MSQVMPALLPHFPLVLVLIAVGVGATEVLVLLVPVKVKFFVRTLVVELDVDELDLEVLGDVDELDLEAPAADDVLELEELVEEDEDEEEEEAPAELLVVTVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4P5</accession>
    <name>G4N4P5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712667.1">
        <property type="nucleotide sequence ID" value="XM_003712619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4P5"/>
    <dbReference type="STRING" id="242507.G4N4P5"/>
    <dbReference type="GeneID" id="2675653"/>
    <dbReference type="KEGG" id="mgr:MGG_05137"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05137"/>
    <dbReference type="eggNOG" id="ENOG502SB4V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032739_1_0_1"/>
    <dbReference type="InParanoid" id="G4N4P5"/>
    <dbReference type="OMA" id="VHMEAVT"/>
    <dbReference type="OrthoDB" id="3365399at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd17080">
        <property type="entry name" value="Ubl_SLD2_Esc2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="439"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="511" mass="56285" checksum="9E80469BCF3BCD9D" modified="2011-12-14" version="1">MDDHDAPVASTATKPKRPLFKKRKVKSASNAPDTTASGEQGVGISTNVNLDEEEDDGLNLFKRSKDFFPVFVKDREEELAAETRKSEESSDRKRRKVSPSADRASPKSDLYDVSEDEKERIRIRRDERPLTPPPTKDKSLLNSSGRRSGQRGVGKGKVNASPASATPSRRAAARPAPSSSIVIFDSEDEYVPRPTASRRSPVETKEPIGSPTPTKQQANNAKPIEIDDDLEEVAPATESLDDEDNEFAHFVVAARERRENQKAVRAAAESVRGTKPVDERIIQVFVTSRLPPPKMKPVVLNTVMRKPIKVLRDTVVAFSASRGRPLTEEEQKGAFLVWKDSRLYSSSTLMSLGVVPDAHGGFSKTGSGNANDGVTVDGQLHFELFTEEIYAEWMQQLEKQRQKDLYQTISDDEGETGQKPAADGQDEAQGQDGKSSEKIRIFLKAKNLDQVKASAKADTEISELVAAFRNVRKIPADKQVVIMFDGDKLAETDTVGDAGIEDKDVVDVLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4W8</accession>
    <name>G4N4W8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U3 small nucleolar RNA-associated protein 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_16744</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711887.1">
        <property type="nucleotide sequence ID" value="XM_003711839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4W8"/>
    <dbReference type="SMR" id="G4N4W8"/>
    <dbReference type="FunCoup" id="G4N4W8">
        <property type="interactions" value="1101"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N4W8"/>
    <dbReference type="GeneID" id="12984240"/>
    <dbReference type="KEGG" id="mgr:MGG_16744"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16744"/>
    <dbReference type="eggNOG" id="KOG1539">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002774_1_0_1"/>
    <dbReference type="InParanoid" id="G4N4W8"/>
    <dbReference type="OMA" id="CIYAWRA"/>
    <dbReference type="OrthoDB" id="10250769at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000565">
        <property type="entry name" value="Putative snoRNA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059157">
        <property type="entry name" value="WDR36-Utp21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007319">
        <property type="entry name" value="WDR36/Utp21_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840:SF12">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25171">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25168">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04192">
        <property type="entry name" value="Utp21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR36/Utp21 N-terminal" evidence="6">
        <location>
            <begin position="63"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="621"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="706"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="WDR36/Utp21 C-terminal" evidence="5">
        <location>
            <begin position="836"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1042" mass="114011" checksum="287D3C99906E0CCA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4Y8</accession>
    <name>G4N4Y8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711907.1">
        <property type="nucleotide sequence ID" value="XM_003711859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4Y8"/>
    <dbReference type="SMR" id="G4N4Y8"/>
    <dbReference type="STRING" id="242507.G4N4Y8"/>
    <dbReference type="GeneID" id="12984247"/>
    <dbReference type="KEGG" id="mgr:MGG_16751"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16751"/>
    <dbReference type="eggNOG" id="KOG1018">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036590_8_1_1"/>
    <dbReference type="InParanoid" id="G4N4Y8"/>
    <dbReference type="OMA" id="PTKFCVG"/>
    <dbReference type="OrthoDB" id="252265at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF162">
        <property type="entry name" value="RIBOFLAVIN BIOSYNTHESIS PROTEIN PYRD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18785">
        <property type="entry name" value="Inv-AAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="180" mass="19873" checksum="7CB43E2B1B4B5DA3" modified="2011-12-14" version="1">METPASATRHTPGNHEEFMKLAIEEARRSRPDPGKFCVGAVLVNEDTGDVLSRGYYLEYPEDYNGSNGSVHAERVCLIKAAELYGVSETELGAALPPNCAIYTTMEPCNARPSMDKPCVERLLEVKQAVRTVYVGIRMPGTSTDAEEPGRRKLEESGGIRVLYPLPEWETELIKVAKGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N507</accession>
    <name>G4N507_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cysteine-rich PDZ-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cysteine-rich interactor of PDZ three</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_16880</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRIPT family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712725.1">
        <property type="nucleotide sequence ID" value="XM_003712677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N507"/>
    <dbReference type="SMR" id="G4N507"/>
    <dbReference type="STRING" id="242507.G4N507"/>
    <dbReference type="GeneID" id="12985177"/>
    <dbReference type="KEGG" id="mgr:MGG_16880"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16880"/>
    <dbReference type="eggNOG" id="ENOG502SR0H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133934_2_1_1"/>
    <dbReference type="InParanoid" id="G4N507"/>
    <dbReference type="OMA" id="KITQGHS"/>
    <dbReference type="OrthoDB" id="147332at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019367">
        <property type="entry name" value="PDZ-binding_CRIPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11805">
        <property type="entry name" value="CYSTEINE-RICH PDZ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11805:SF1">
        <property type="entry name" value="CYSTEINE-RICH PDZ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10235">
        <property type="entry name" value="Cript"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="119" mass="12398" checksum="4B1CD0121971D894" modified="2011-12-14" version="1">MVCGKCQKLSKGTSLATPSVKKKSEMYYGSPASSSASKSSATLGQTGVSKNKLLSKGAKNPYAQYSSSCDKCKTKVSQGHKYCHSCAYKADACAMCGKSNSKSKTGSVPVVTGQKFSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N571</accession>
    <name>G4N571_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Mitochondrial fission 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_06075</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the FIS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711937.1">
        <property type="nucleotide sequence ID" value="XM_003711889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N571"/>
    <dbReference type="SMR" id="G4N571"/>
    <dbReference type="FunCoup" id="G4N571">
        <property type="interactions" value="685"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N571"/>
    <dbReference type="GeneID" id="2684234"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06075"/>
    <dbReference type="eggNOG" id="KOG3364">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104368_2_0_1"/>
    <dbReference type="InParanoid" id="G4N571"/>
    <dbReference type="OMA" id="QFNYAWG"/>
    <dbReference type="OrthoDB" id="421154at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000179">
        <property type="entry name" value="Mitochondrial fission 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028058">
        <property type="entry name" value="Fis1_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14852">
        <property type="entry name" value="Fis1_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008835">
        <property type="entry name" value="TPR_repeat_11_Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA52130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="154" mass="16937" checksum="D0D51F5508107CE9" modified="2011-12-14" version="1">MGTNLPYAIDAETPLQPAELAVLRAQYDKEGDMVGVQTKFNYAWGLVKSSTRSDQQLGVMLLSEIFRTSPERRRECLYYLALGNYKLGNYAEARRYNDLLLGKEPTNLQATNLRSLIDDKVAKEGLLGAAIIGGVAVAASVVGGILIRNMGRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>G4N586</accession>
    <name>G4N586_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_16756</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711951.1">
        <property type="nucleotide sequence ID" value="XM_003711903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N586"/>
    <dbReference type="GeneID" id="12984253"/>
    <dbReference type="KEGG" id="mgr:MGG_16756"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16756"/>
    <dbReference type="eggNOG" id="ENOG502S5V9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017004_1_0_1"/>
    <dbReference type="InParanoid" id="G4N586"/>
    <dbReference type="OMA" id="YEHFWQM"/>
    <dbReference type="OrthoDB" id="2406834at2759"/>
    <dbReference type="PHI-base" id="PHI:5615"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF81">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="116"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="86"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA52144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="668" mass="73806" checksum="B8AD815121976AFD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5E0</accession>
    <name>G4N5E0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05247</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712804.1">
        <property type="nucleotide sequence ID" value="XM_003712756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5E0"/>
    <dbReference type="SMR" id="G4N5E0"/>
    <dbReference type="FunCoup" id="G4N5E0">
        <property type="interactions" value="89"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5E0"/>
    <dbReference type="GeneID" id="2675596"/>
    <dbReference type="KEGG" id="mgr:MGG_05247"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05247"/>
    <dbReference type="eggNOG" id="KOG2250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005220_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5E0"/>
    <dbReference type="OMA" id="DEYGMTS"/>
    <dbReference type="OrthoDB" id="184415at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016210">
        <property type="entry name" value="NAD-GDH_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000184">
        <property type="entry name" value="GDH_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="681"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1045" mass="117073" checksum="5429512494DF829A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6F2</accession>
    <name>G4N6F2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03738</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716141.1">
        <property type="nucleotide sequence ID" value="XM_003716093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6F2"/>
    <dbReference type="STRING" id="242507.G4N6F2"/>
    <dbReference type="GeneID" id="2676789"/>
    <dbReference type="KEGG" id="mgr:MGG_03738"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03738"/>
    <dbReference type="eggNOG" id="ENOG502S0AR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030037_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6F2"/>
    <dbReference type="OMA" id="DRRFFPR"/>
    <dbReference type="OrthoDB" id="3219396at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039719">
        <property type="entry name" value="FBXO28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13252">
        <property type="entry name" value="F-BOX ONLY PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13252:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="643" mass="70925" checksum="418AFD01B81ED81A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7E8</accession>
    <name>G4N7E8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03584</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716326.1">
        <property type="nucleotide sequence ID" value="XM_003716278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7E8"/>
    <dbReference type="GeneID" id="2677000"/>
    <dbReference type="KEGG" id="mgr:MGG_03584"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03584"/>
    <dbReference type="eggNOG" id="ENOG502SMK9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_4_1"/>
    <dbReference type="InParanoid" id="G4N7E8"/>
    <dbReference type="OMA" id="DLEYAHC"/>
    <dbReference type="OrthoDB" id="3648173at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="33"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="364"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="367"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="411" mass="44914" checksum="75C9A86AC36C357A" modified="2011-12-14" version="1">MIVDHSLDHEDMSGVVVGVVSVCLVLITLAVAARVYTRLVILRTFGPDDYAAVLSLFFTFACGLVIGMMVRHGSGKHVWTLQPSDIEAYLIEFYLSIVFYNASIMATKAAFLLQYYRVLAVNRGMKRIYLGFLILIAAWCFGFVLVAIFQCSPISDFWSSAPTRNCLPNMPYWKVQGVGHIITDILVFTLPLPALYQLHINGTQKLVLMGIFSLGFFACAISVIRLRYLVVAEDVTWDNTVPSIWSTTEVTIGLLCACLPTLRPLVGRLFPKLVSTFNKSLAGPGGESGAGIGYHKGASKAGGGHSKNRSLVTTSSTFSKARSAYRENSGSVERLRVDVNGTDSSSAVKEESFLDDISEAGSPRGFNMQTFGTKTKVTTGRDQARPVDSWESPSLPAGQIRVSRDVYQTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N825</accession>
    <name>G4N825_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Tricarboxylate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_03479</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716446.1">
        <property type="nucleotide sequence ID" value="XM_003716398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N825"/>
    <dbReference type="SMR" id="G4N825"/>
    <dbReference type="STRING" id="242507.G4N825"/>
    <dbReference type="GeneID" id="2676828"/>
    <dbReference type="KEGG" id="mgr:MGG_03479"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03479"/>
    <dbReference type="eggNOG" id="KOG0756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_5_1_1"/>
    <dbReference type="InParanoid" id="G4N825"/>
    <dbReference type="OMA" id="AWYAGCT"/>
    <dbReference type="OrthoDB" id="44467at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071913">
        <property type="term" value="F:citrate secondary active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006843">
        <property type="term" value="P:mitochondrial citrate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000092">
        <property type="entry name" value="Mitochondrial tricarboxylate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000064">
        <property type="entry name" value="Mitochondrial tricarboxylate transporter (Ctp)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF4">
        <property type="entry name" value="TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="102"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="192"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="289"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="64"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA50127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="386" mass="41667" checksum="4EA84046C9676805" modified="2011-12-14" version="1">MQPGEIASSTPHSSPGDSADSSPTVAHRRKTLATISLVTSRTQDCQQNCHWPSFESFRYSTAGPRDELTHCKNPPSPDMAAQPQQQNEKGDAPVAASMKKGPSALRSIIAGSTAGAVEIAITYPAEFAKTRTQLNRNLAEGQKLPWPPFGKQWYAGCTTLIIGNSAKAGIRFVAFDQYKSLLADENGKMSGPRTVLAGFGAGVTESLLAVTPTESIKTTLIEDRKSAKPRLRGFLHAVPIIARERGIKGFFQGFVPTTARQSANSATRFSAYTFLRQMAESYTAPGEKLGTVGTFAVGGVAGLITVYVTQPLDTIKTRMQSSEAKSVYGNSFRCASIIFKQEGILTFWSGALPRLARLIMSGGIVFTMYEKSMDLMGRMDPDGKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8I9</accession>
    <name>G4N8I9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_06237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717356.1">
        <property type="nucleotide sequence ID" value="XM_003717308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8I9"/>
    <dbReference type="SMR" id="G4N8I9"/>
    <dbReference type="STRING" id="242507.G4N8I9"/>
    <dbReference type="GeneID" id="2684392"/>
    <dbReference type="KEGG" id="mgr:MGG_06237"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06237"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010578_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8I9"/>
    <dbReference type="OMA" id="WDIFCTL"/>
    <dbReference type="OrthoDB" id="42889at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF146">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="55633" checksum="917D377981B67B68" modified="2011-12-14" version="1">MSTANDKRFATLVEWNKANGGRLNPAVEVYNDLITKVSLRAKEAVTPDADGHCATVSCPLSTTLSVLNALTGSPLSTSTSGENGSPAQSPPAFPDYFLQNVPPHVVSRFFLIQQYLLGPKSHWHPYIASLPQPEHLASWNLPPFWPEEDAAVLAATNAGVAAKEMAGIAGRESKQGRRALRESGLENWREYSPLLYRWAYCIFTSRSFRPSLVVPPAVWESLRNEHAKYLDGCEMDDFSILMPLFDIANHDPLVQATWDSESVPGECRLLVNGRSGQGYRPGEQIFNNYGLKTNSELLVAYGFVLSESDDLQNEYFHVRLQTQGPADETTGKRPTIPRDFLISLDPLSSPRSVVGRARQWIHDRQGLRKDFDHCEDALLWAFCEVYLQVQGLDHGAKVARLASILADSSPAEHEQLIESLRDFFVNKLEFDYAKISAGGSEAMRTLLAKRRNAKEAEGSTSGNQDLAMRYLTAVLRVIQIAMVTLDPSIEFQYTPEEGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8J0</accession>
    <name>G4N8J0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_03431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716503.1">
        <property type="nucleotide sequence ID" value="XM_003716455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8J0"/>
    <dbReference type="SMR" id="G4N8J0"/>
    <dbReference type="GeneID" id="2676529"/>
    <dbReference type="KEGG" id="mgr:MGG_03431"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03431"/>
    <dbReference type="eggNOG" id="ENOG502SKX1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_640944_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8J0"/>
    <dbReference type="OMA" id="IYNMSAN"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="47185" checksum="B14A1D89B2F9049F" modified="2011-12-14" version="1">MSYTLPPADESSIQGLDFTDKPYHTSHIDPVQRFYENVEQVKAFIKENISNFSGLDEKVLFLLGDDATFPCQPVCVDATANPPVVTTTAPEPSSTPPKTITILPEYVLDAIEGRMHAQHAFGKRARPPTLGAVPACFSPGGVPGFCAGVADAHAPLPRPTEDVAQLKRDLTAWGYAICANALSARQVQILRAAVEEQAEAERLVGVGHLDSAHKREGDQPNQRVWNLPNKGDEFLDLLNHPIIDAVLPWFLGGNFNLFTMSANIARPGSSGIYMHRDQMGLTPDTTAHAYVLNMMWYLTDVTDEKGATRIYPGSHVEHVIPEEMNAVGKSIPAAAPAGSCVLLDSRTWHSTGVNTTEETRPVILQSFCRFFVRQIENYQANLSDEVKAKLSDRQRTLLGFPSLKPAGKGQGFAAYNWPGTQVGRLRASLGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8L1</accession>
    <name>G4N8L1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716524.1">
        <property type="nucleotide sequence ID" value="XM_003716476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8L1"/>
    <dbReference type="SMR" id="G4N8L1"/>
    <dbReference type="GeneID" id="2676975"/>
    <dbReference type="KEGG" id="mgr:MGG_03414"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03414"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_12_1_1"/>
    <dbReference type="InParanoid" id="G4N8L1"/>
    <dbReference type="OMA" id="LFTDFSM"/>
    <dbReference type="OrthoDB" id="2962696at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF18">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G12480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="311" mass="32259" checksum="02729691DB863004" modified="2011-12-14" version="1">MGDTSLAATAAAALFRVDGIVAVITGGGTGIGLMMTKALLNNGAKKVYILGRRMEVLEKAVEECGAAAKGVVVPVQCDVTSKPSIQGAVDVVTSEVGYVNLVVANSGAFGPPNRYDPTKTISELRQTLFDDVDMNEVTQTFHINVTGAYFTMLGFLELLDAGNKSAVDKGTYGAPLTPGGTAPSIQSQVVFNASVAGYLKSIRSPPSYGGSKAALLQLTKVAATMLATYGIRVNGLAPGLFPSELASVLIGSRNPETESPDLPTFIPARKFGGDEEMGGTILYLASRAGSYCDGLILVVDGGRLAFTNSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8Z8</accession>
    <name>G4N8Z8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717412.1">
        <property type="nucleotide sequence ID" value="XM_003717364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8Z8"/>
    <dbReference type="GeneID" id="2681713"/>
    <dbReference type="KEGG" id="mgr:MGG_10102"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10102"/>
    <dbReference type="HOGENOM" id="CLU_1129244_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8Z8"/>
    <dbReference type="OrthoDB" id="10444654at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465877" evidence="2">
        <location>
            <begin position="23"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="246" mass="25897" checksum="9F6F93F62E59C7B1" modified="2011-12-14" version="1">MQFSTYYATLAILAGLSAQVAAMPISSTGAELQARSCETNPYGCGLNPKSNPDAPDKRDLESKSELDARSCETNPAACGINGFVDNGHVVTTGPIRGKAKREEEEEEGEDAAEVDAAELDARSCETNPAACGINGFVENGHVVTTGPIRGKVKRAEEEEEDEDAAELDARSCETNPAACGINGFVDNGHVVTTGPIRGKAKREEEEDEEEDAAELDARSCETNPAACGNNGFVQDGHVVVTGRIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9E2</accession>
    <name>G4N9E2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Aquaporin-9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_13615</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>glycerol(in) = glycerol(out)</text>
            <dbReference type="Rhea" id="RHEA:29675"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717502.1">
        <property type="nucleotide sequence ID" value="XM_003717454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9E2"/>
    <dbReference type="SMR" id="G4N9E2"/>
    <dbReference type="STRING" id="242507.G4N9E2"/>
    <dbReference type="GeneID" id="5050038"/>
    <dbReference type="KEGG" id="mgr:MGG_13615"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13615"/>
    <dbReference type="eggNOG" id="KOG0224">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020019_9_0_1"/>
    <dbReference type="InParanoid" id="G4N9E2"/>
    <dbReference type="OMA" id="WGFAVLT"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1080.10:FF:000027">
        <property type="entry name" value="MIP aquaporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02019">
        <property type="entry name" value="AQUAPORIN7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA51183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="39059" checksum="8B5EF5C764F7E63A" modified="2011-12-14" version="1">MAHVTEIYTVKTPDSATFPPGTIEKTNVLMSKEESSSDLTTKGSHHEDVADPRDSVIPPGNGPVPPELAWTRVRTIWQDAFSEFIGTMVLILFGDGVVAQVVLSRGTKGEYQSISWGWGIGVMFGVYCSMKSGGHINPAVTFANCVYRKFPWRRFPIYAIAQILGAMVGAAIVYGNYKAAFDFFEGGEGIRTVVGENATAGVFCTYPAPFMTRTGMFFSEVVASAILMLVIYALVDNDAGHLMPLALFFLIFGIGACFGWETGYAINLARDFGPRLVSYMIGYGDEVWSAGGYYFWIPMVAPFFGCLLGGFIYDAFLYTGESPINTPWMGFKRLTQPRRDVWSNTYQRKEISNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9S6</accession>
    <name>G4N9S6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ADP-ribosylation factor 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_10676</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715902.1">
        <property type="nucleotide sequence ID" value="XM_003715854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9S6"/>
    <dbReference type="SMR" id="G4N9S6"/>
    <dbReference type="FunCoup" id="G4N9S6">
        <property type="interactions" value="80"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9S6"/>
    <dbReference type="GeneID" id="2682877"/>
    <dbReference type="KEGG" id="mgr:MGG_10676"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10676"/>
    <dbReference type="eggNOG" id="KOG0071">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040729_9_3_1"/>
    <dbReference type="InParanoid" id="G4N9S6"/>
    <dbReference type="OMA" id="GGQISKM"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="PHI-base" id="PHI:9547"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04149">
        <property type="entry name" value="Arf6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000832">
        <property type="entry name" value="ADP-ribosylation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041838">
        <property type="entry name" value="Arf6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="186" mass="20915" checksum="CE8114D29F70EC7B" modified="2011-12-14" version="1">MGGQLSKMMGKIFGSKEMRLLMLGLDAAGKTTILYKLKLGQDVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYFSGTQGLIFVIDSSDRKRMDEARQELHRIINDREMKDSLLLVFANKQDLENAMKPQEVTEALQLSKLKDKIWYVVPSCATTGEGLLEGLAWLSNNVKAPPAPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9T1</accession>
    <name>G4N9T1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HeH/LEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_10673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715907.1">
        <property type="nucleotide sequence ID" value="XM_003715859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9T1"/>
    <dbReference type="SMR" id="G4N9T1"/>
    <dbReference type="GeneID" id="2682874"/>
    <dbReference type="KEGG" id="mgr:MGG_10673"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10673"/>
    <dbReference type="HOGENOM" id="CLU_1195075_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9T1"/>
    <dbReference type="OrthoDB" id="5228327at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="26503" checksum="47441CFB20320F84" modified="2011-12-14" version="1">MSPTQLHQFTYPSPPSPTPDPPPPSPTFEDWWSTQVKQHPFLSPTFDPWRATVPVLRRSLVALGFPMTPGARKPALVRAFEHNAPLLVPQFEANLKACFPPSPPQALRPRGVKRARGARDADEAERRGEGDETKRREDDDEAARARLQLKRQKLAALDRDELDDLVQFRDDMRTAERRLEASMGEFESVRWKVQRLLGELNKGLAALDDARAKCAEWRESMTDDLRLWLSMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9Y0</accession>
    <name>G4N9Y0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino-acid N-acetyltransferase subunit Mak10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03228</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAK10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9Y0"/>
    <dbReference type="SMR" id="G4N9Y0"/>
    <dbReference type="FunCoup" id="G4N9Y0">
        <property type="interactions" value="614"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9Y0"/>
    <dbReference type="GeneID" id="2676462"/>
    <dbReference type="KEGG" id="mgr:MGG_03228"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03228"/>
    <dbReference type="eggNOG" id="KOG2343">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011757_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9Y0"/>
    <dbReference type="OMA" id="QMEWIVQ"/>
    <dbReference type="OrthoDB" id="269405at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="NAA35-like_N"/>
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    <dbReference type="InterPro" id="IPR007244">
        <property type="entry name" value="Naa35_N"/>
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    <dbReference type="InterPro" id="IPR057982">
        <property type="entry name" value="TPR_NAA35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373">
        <property type="entry name" value="GLUCOSE REPRESSIBLE PROTEIN MAK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373:SF0">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Mak10"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR_NAA35"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="68"/>
            <end position="239"/>
        </location>
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        <location>
            <begin position="357"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="791" mass="89981" checksum="F47A53CC9A12D3A2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAF4</accession>
    <name>G4NAF4_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_03172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716818.1">
        <property type="nucleotide sequence ID" value="XM_003716770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAF4"/>
    <dbReference type="SMR" id="G4NAF4"/>
    <dbReference type="STRING" id="242507.G4NAF4"/>
    <dbReference type="GeneID" id="2676833"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_03172"/>
    <dbReference type="HOGENOM" id="CLU_389818_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAF4"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <location>
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        </location>
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            <begin position="115"/>
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        <location>
            <begin position="221"/>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="708" mass="81766" checksum="5A8DFE2520284421" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAH9</accession>
    <name>G4NAH9_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">Aldo-keto reductase yakc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003717588.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NAH9"/>
    <dbReference type="SMR" id="G4NAH9"/>
    <dbReference type="GeneID" id="2680669"/>
    <dbReference type="KEGG" id="mgr:MGG_09715"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09715"/>
    <dbReference type="eggNOG" id="KOG1575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_2_1_1"/>
    <dbReference type="InParanoid" id="G4NAH9"/>
    <dbReference type="OMA" id="CTHWDTS"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
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    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF40">
        <property type="entry name" value="ALDO-KETO REDUCTASE YAKC [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="341" mass="38007" checksum="5A11C8E55607648B" modified="2011-12-14" version="1">MAPPAQIPTRRMGKDGPEVACIGFGLMGLSFGYGAVESEEERFKVLDRAWEIGATNWDTADIYGDSEDLVGKWFKMHPERRKDIFLATKFGVTGTIENLSANSSPEYCRQASRRSFERLGVDYVDLYYVHRLTESVPVEKTIEAMAELVKEGKVKYLGMSECSSSSVRRAHKVHPIAAVQVEYNPWDLAIEGDEGTNLLATCRELGISVVAYSPFSRGLLTGALKSREDFNDPTDCRLFLPRYSEENFPKNLELVAEIEKIAKEKGCTSGQLVLAWLLAQGNEIIPIPGTKRIKFLEENTAAAHVKLTAEEEKKIRNLVDKANIQGDRGAFINSYGDTVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAS8</accession>
    <name>G4NAS8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03154</name>
    </gene>
    <organism evidence="3 4">
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            <taxon>Pezizomycotina</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Djonovic S."/>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
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                <person name="Djonovic S."/>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
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                <person name="MacDonald P.J.P."/>
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                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="208" mass="23444" checksum="13CB9405EA8CE49B" modified="2011-12-14" version="1">MIYHNGFWINEKARNNPFYPPKTASNGQPPNTNCRWDLEYAFDSEEESDSSGDYKGNHHDQLLLTAETLRDGTTLKGTSSGLSPTTASSTTENSRKRRKGNDCSIVPKITVTSPDGLVSYGSWDTHVRMVRLQTSPPDARLLHFEWRPARTSAEPGCQSSSLQHEQGQFTLATIDDGIARLVMKKKVNVEDRNGDDKLLDYEEYDWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC08</accession>
    <name>G4NC08_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00469</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718595.1">
        <property type="nucleotide sequence ID" value="XM_003718547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC08"/>
    <dbReference type="SMR" id="G4NC08"/>
    <dbReference type="FunCoup" id="G4NC08">
        <property type="interactions" value="39"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NC08"/>
    <dbReference type="GeneID" id="2674226"/>
    <dbReference type="KEGG" id="mgr:MGG_00469"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00469"/>
    <dbReference type="eggNOG" id="KOG1396">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006633_0_1_1"/>
    <dbReference type="InParanoid" id="G4NC08"/>
    <dbReference type="OMA" id="EFFCPVS"/>
    <dbReference type="OrthoDB" id="266334at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045120">
        <property type="entry name" value="Suco/Slp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12953">
        <property type="entry name" value="MEMBRANE PROTEIN CH1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12953:SF0">
        <property type="entry name" value="SUN DOMAIN-CONTAINING OSSIFICATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07738">
        <property type="entry name" value="Sad1_UNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51469">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466337" description="SUN domain-containing protein" evidence="7">
        <location>
            <begin position="30"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="domain" description="SUN" evidence="8">
        <location>
            <begin position="214"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="74"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="388"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="463"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="543"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="778"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="831"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="863"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="703"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="412"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="499"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="559"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="585"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="975" mass="105198" checksum="B8D5693D6C741D95" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCP7</accession>
    <name>G4NCP7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Splicing factor 3B subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_00356</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3B1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718725.1">
        <property type="nucleotide sequence ID" value="XM_003718677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCP7"/>
    <dbReference type="SMR" id="G4NCP7"/>
    <dbReference type="FunCoup" id="G4NCP7">
        <property type="interactions" value="999"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NCP7"/>
    <dbReference type="GeneID" id="2674968"/>
    <dbReference type="KEGG" id="mgr:MGG_00356"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00356"/>
    <dbReference type="eggNOG" id="KOG0213">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002242_0_1_1"/>
    <dbReference type="InParanoid" id="G4NCP7"/>
    <dbReference type="OMA" id="LVMNYVW"/>
    <dbReference type="OrthoDB" id="438939at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140727">
        <property type="term" value="P:siRNA-mediated pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000039">
        <property type="entry name" value="Splicing factor 3B subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000088">
        <property type="entry name" value="Splicing factor 3b, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015016">
        <property type="entry name" value="SF3b_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038737">
        <property type="entry name" value="SF3b_su1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12097">
        <property type="entry name" value="SPLICING FACTOR 3B, SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08920">
        <property type="entry name" value="SF3b1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Splicing factor 3B subunit 1" evidence="9">
        <location>
            <begin position="239"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="10">
        <location>
            <begin position="1000"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="133"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA49141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1215" mass="135349" checksum="3201F484D0AD98C3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCR5</accession>
    <name>G4NCR5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_00339</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718743.1">
        <property type="nucleotide sequence ID" value="XM_003718695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCR5"/>
    <dbReference type="STRING" id="242507.G4NCR5"/>
    <dbReference type="GeneID" id="2674993"/>
    <dbReference type="KEGG" id="mgr:MGG_00339"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00339"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028281_6_1_1"/>
    <dbReference type="InParanoid" id="G4NCR5"/>
    <dbReference type="OMA" id="DGHHYGN"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466451" description="SET domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="157"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="456" mass="49878" checksum="3CD1EF8B6FF7C972" modified="2011-12-14" version="1">MPLSRVSSFVPVCLLLGLLMGVCHSSRPEAHQHHGPHGVCHWSRPGQSLFQPCCSVQSNEDGLVLEGMDGLDWEGSAKDRSSSGPARPANASNTNAWDTPWRGPHACAGEFCVYSNPGFANGHGMVFIGKARNAEILARVLKASSGSASDNTLADRTLFERKEIPGKGVGLVARRPISRGQLIMAQRPALVTDIKTFDISDDDQTRLFDAGIEQLPSETVMEFLSQASQTDSTKRGAKIRDIANTNSFNLNIAGVPHAGTFLGVSRLNHDCRPNLAFHVAKSFVHTTHATRDIAAGEELTISYVDSYSSRNVRQERLKRNWGFTCTCPHCSLSEAMGKLSDSRLYAIYQLDNSLRNLTWREDGPALPNSVELMLSLIRQERLDFSLAEAYRLAAETHGSLGSRELALKYAHLALEAGVVEQGAASPLVVDMEDFVKDPSSHWSWLKRVDGSGNEMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND67</accession>
    <name>G4ND67_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717993.1">
        <property type="nucleotide sequence ID" value="XM_003717945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND67"/>
    <dbReference type="SMR" id="G4ND67"/>
    <dbReference type="FunCoup" id="G4ND67">
        <property type="interactions" value="488"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ND67"/>
    <dbReference type="GeneID" id="2674614"/>
    <dbReference type="KEGG" id="mgr:MGG_00957"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00957"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_2_5_1"/>
    <dbReference type="InParanoid" id="G4ND67"/>
    <dbReference type="OMA" id="RCNPEDI"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF19">
        <property type="entry name" value="AARF DOMAIN-CONTAINING PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="220"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="658" mass="72518" checksum="F8759522DD218168" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-02-13" modified="2025-02-05" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEA9</accession>
    <name>NEC2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">O-methyltransferase NEC2</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nectriapyrone biosynthesis cluster protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NEC2</name>
        <name type="ORF">MGG_14657</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2019" name="ChemBioChem" volume="20" first="693" last="700">
            <title>Induction of nectriapyrone biosynthesis in the rice blast fungus Pyricularia oryzae by disturbance of the two-component signal transduction system.</title>
            <authorList>
                <person name="Motoyama T."/>
                <person name="Nogawa T."/>
                <person name="Hayashi T."/>
                <person name="Hirota H."/>
                <person name="Osada H."/>
            </authorList>
            <dbReference type="PubMed" id="30443971"/>
            <dbReference type="DOI" id="10.1002/cbic.201800620"/>
        </citation>
        <scope>IDENTIFICATION</scope>
        <scope>INDUCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
    </reference>
    <comment type="function">
        <text evidence="2">O-methyltransferase; part of the gene cluster that mediates the biosynthesis of nectriapyrone and its analogs phomopyrone A, acropyrone and zaepyrone (PubMed:30443971). The nectriapyrone biosynthetic gene cluster consists of two genes, the highly reducing polyketide synthase NEC1 that produces a demethylated analog of nectriapyrone from one unit of acetyl-CoA and one unit of malonyl-CoA; and the O-methyltransferase NEC2 that further methylates the NEC1 product to yield nectriapyrone (PubMed:30443971). Nectriapyrone is further hydrolyzed to nectriapyrone D, also known as gulypyrone B, by an unidentified hydrolase localized outside the nectriapyrone cluster (PubMed:30443971).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>desmethylnectriapyrone + S-adenosyl-L-methionine = nectriapyrone + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:58748"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:142639"/>
            <dbReference type="ChEBI" id="CHEBI:142640"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:58749"/>
        </physiologicalReaction>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="2">Completely abolishes the production of nectriapyrones but accumulates a demethylated analog of nectriapyrone.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718176.1">
        <property type="nucleotide sequence ID" value="XM_003718128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEA9"/>
    <dbReference type="EnsemblFungi" id="MGG_14657T0">
        <property type="protein sequence ID" value="MGG_14657T0"/>
        <property type="gene ID" value="MGG_14657"/>
    </dbReference>
    <dbReference type="GeneID" id="5050752"/>
    <dbReference type="KEGG" id="mgr:MGG_14657"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14657"/>
    <dbReference type="eggNOG" id="ENOG502SJSY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046029_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEA9"/>
    <dbReference type="OMA" id="VWRCPLP"/>
    <dbReference type="OrthoDB" id="10061782at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000446266" description="O-methyltransferase NEC2">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="30443971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="3">
        <source>
            <dbReference type="PubMed" id="30443971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="265" mass="29680" checksum="516221872DE9D2AB" modified="2011-12-14" version="1">MASSRDRAYVTVYSPTLLTWVYDYYVLGFNLRYIWGCPTDAVLLPFFAENFSRRHLDVGVATGYLPARVLASPWRRAAAHRQHLTLLDINANSLRASDARVRAAAPGIETTCVEADVVADLPPVLASVVEEERARVEKAGGEAGSSSRSCLYDSISMFNLFHCVPGGPAKLRAISTYKALLADHGVLSGCTVLGERHATGWFSRWYLRLYNRKGIFNNINDTREEFEEVLNKEFEEVDTWMFGMVLLFRASKPRREGSGYVDLLA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2016-04-13" modified="2025-04-09" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEE4</accession>
    <name>VELC_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sexual development regulator VELC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VELC</name>
        <name type="ORF">MGG_14719</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2014" name="Fungal Genet. Biol." volume="66" first="33" last="43">
            <title>Comparative functional analysis of the velvet gene family reveals unique roles in fungal development and pathogenicity in Magnaporthe oryzae.</title>
            <authorList>
                <person name="Kim H.J."/>
                <person name="Han J.H."/>
                <person name="Kim K.S."/>
                <person name="Lee Y.H."/>
            </authorList>
            <dbReference type="PubMed" id="24632440"/>
            <dbReference type="DOI" id="10.1016/j.fgb.2014.02.011"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Velvet-domain-containing protein that acts as a positive regulator of sexual development (PubMed:24632440). Plays an important role in pathogenicity through regulating positively appressorium-mediated penetration and invasive growth (PubMed:24632440).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="3">Leads to reduced formation of conidia (PubMed:24632440). Exhibits significantly reduced pathogenicity, developing only a few small necrotic lesions (PubMed:24632440).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the velvet family. VelC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719005.1">
        <property type="nucleotide sequence ID" value="XM_003718957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEE4"/>
    <dbReference type="SMR" id="G4NEE4"/>
    <dbReference type="STRING" id="242507.G4NEE4"/>
    <dbReference type="EnsemblFungi" id="MGG_14719T0">
        <property type="protein sequence ID" value="MGG_14719T0"/>
        <property type="gene ID" value="MGG_14719"/>
    </dbReference>
    <dbReference type="GeneID" id="5049346"/>
    <dbReference type="KEGG" id="mgr:MGG_14719"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14719"/>
    <dbReference type="eggNOG" id="ENOG502RYR6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022491_3_3_1"/>
    <dbReference type="InParanoid" id="G4NEE4"/>
    <dbReference type="OMA" id="ENGEDGC"/>
    <dbReference type="OrthoDB" id="3056235at2759"/>
    <dbReference type="PHI-base" id="PHI:4111"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF17">
        <property type="entry name" value="SEXUAL DEVELOPMENT REGULATOR VELC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0749">Sporulation</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <feature type="chain" id="PRO_0000435919" description="Sexual development regulator VELC">
        <location>
            <begin position="1"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Velvet" evidence="1">
        <location>
            <begin position="213"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="396"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="24632440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="4">
        <source>
            <dbReference type="PubMed" id="24632440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA49421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="442" mass="47456" checksum="E66A55527A7EBB5B" modified="2011-12-14" version="1">MPVHFNQSVGMPPARDGARPPPIKGGLMGKLIPATYSPNGRHPRIAPPPPPTPPAGAGAGAGAAPPQRQLLQHSPTTAPGPRRPSNPSSPQHPQQPGIDRFPQIIPYQHEQPQRRPSRQQYSASPPVDYSFGKGPKQSGLDQSSSTSSSVSPKQEMKQMSIHNLLSSGDQDDQDDKSINNSNTARASSASLASLASPRSVLPPAAMPSPSPSFSTSEYHLHVRQQPVAARSCGFGERDRRVIDPPPIVQMTIDDPSATPDQMQQRLRHPFSVVHCSIYNETGEEDNSAMPEDYRQQRRLMGTLVASPFVGKDENGEDGCFFCFPDLSCRTPGSFRLKFSLVVINPADMRQGLRTPIAATAMSDVLVVYNAKDFPGMQASTPLTRKLKEQGCLISIKKGNEKGGGGGGGGPSGSRDQYSDDEYDDDGGGGSGRAGKRKRIRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEI4</accession>
    <name>G4NEI4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4419 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719045.1">
        <property type="nucleotide sequence ID" value="XM_003718997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEI4"/>
    <dbReference type="GeneID" id="2674427"/>
    <dbReference type="KEGG" id="mgr:MGG_00095"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00095"/>
    <dbReference type="eggNOG" id="ENOG502RPX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037155_3_0_1"/>
    <dbReference type="InParanoid" id="G4NEI4"/>
    <dbReference type="OMA" id="MGLMQHY"/>
    <dbReference type="OrthoDB" id="9978173at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025533">
        <property type="entry name" value="DUF4419"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31252">
        <property type="entry name" value="DUF4419 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31252:SF11">
        <property type="entry name" value="DUF4419 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14388">
        <property type="entry name" value="DUF4419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466438" description="DUF4419 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="48488" checksum="F663D1199E1291E5" modified="2011-12-14" version="1">MGCTRALKSLTLLSVIGLSVVTGHITVLPGGDPKPYIGSDAILSCEDFFLQSAERDFVNFNGSIILSSYDSASFSAEEGLRSSSDSFVRGAIQAWGEHLHLVVRPEEVWFTILTQMNFFMNAHAESLRDLFVSHQGKEVIYIEDWTWEAVIIRFQDEIQKRVKTDWLQDWIMPNFTTTTDSDRMTASLLMMGLTQAYFKFEGGIVCGLPSVTLLGDKSDWEALLAKLDHLSAFGEEPETYAARLRPILTRFVSTFDAPDSPDTLRFWNDIVTARQGTVCGQPPYYISGWITGFHYWDDKGRSFARRNGALRLDNVTYAEVDPRQLPVGYAKVPFTMHDYPSPGLKTEAVLMAGTLGKKVVSGAPGGYAGALQRAGQEEDPVLGGTSVHYTLQPLSGWALYGPVDTNATVRYVEEWELANLTSSVRANFVEGRCGARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF77</accession>
    <name>G4NF77_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_17669</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719592.1">
        <property type="nucleotide sequence ID" value="XM_003719544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF77"/>
    <dbReference type="STRING" id="242507.G4NF77"/>
    <dbReference type="GeneID" id="12986081"/>
    <dbReference type="KEGG" id="mgr:MGG_17669"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17669"/>
    <dbReference type="eggNOG" id="ENOG502RIXY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006173_0_0_1"/>
    <dbReference type="InParanoid" id="G4NF77"/>
    <dbReference type="OMA" id="IRCDGRP"/>
    <dbReference type="OrthoDB" id="4456959at2759"/>
    <dbReference type="PHI-base" id="PHI:5617"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF4">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="686"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="689"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA47225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="925" mass="102634" checksum="6504ACAFD7FC90DD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF86</accession>
    <name>G4NF86_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_12178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719601.1">
        <property type="nucleotide sequence ID" value="XM_003719553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF86"/>
    <dbReference type="STRING" id="242507.G4NF86"/>
    <dbReference type="GeneID" id="2677440"/>
    <dbReference type="KEGG" id="mgr:MGG_12178"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12178"/>
    <dbReference type="eggNOG" id="ENOG502SXHQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065008_0_0_1"/>
    <dbReference type="InParanoid" id="G4NF86"/>
    <dbReference type="OMA" id="TNCCITF"/>
    <dbReference type="OrthoDB" id="5226655at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="298" mass="31645" checksum="6F1CCDB1B2AA365C" modified="2011-12-14" version="1">MGRPSDANLPEVVPGDFPQTVPDSSPQALTAAEAEAHRPRLGDAHLYPDGVEVVDYPKYIEVPVGLEAAHQNPYSPSAPSSAPWEPISAVDRLQAGRVDSHGSQADSDDAVKPTPKTIWGLPPKHFYLLIAVLLLLAVAIGAGVGAGVTAANNRAAQRETQGDGGSASSDNGSGSSPRPTTTGPKPLTPTGTPYDPPLNESDPDGPFVFQGWSGANFTGNMTIKYRKYGIFDLEFPVISYVWDPNGYTCCISFCANNTDTSGKYRCQYRKQELASAHFGRIHTYCGGNDITKSAMSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFX3</accession>
    <name>G4NFX3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719297.1">
        <property type="nucleotide sequence ID" value="XM_003719249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFX3"/>
    <dbReference type="GeneID" id="2684804"/>
    <dbReference type="KEGG" id="mgr:MGG_11072"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11072"/>
    <dbReference type="HOGENOM" id="CLU_1982024_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFX3"/>
    <dbReference type="OrthoDB" id="5233314at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466248" evidence="2">
        <location>
            <begin position="24"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="126" mass="13595" checksum="503783AACC382ADB" modified="2011-12-14" version="1">MQIKTFAATLFIAFAAALPGASTEGTERSEAVGAATDSTERSDAVGATPDVAETSTFRDGVAVSQKTWQADGHCEFKYWSLENCITRCIYEAKFGPQRCPKSNDINGNRTGGCLPFRDTCECTCTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG04</accession>
    <name>G4NG04_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01941</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719328.1">
        <property type="nucleotide sequence ID" value="XM_003719280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG04"/>
    <dbReference type="SMR" id="G4NG04"/>
    <dbReference type="STRING" id="242507.G4NG04"/>
    <dbReference type="GeneID" id="2681156"/>
    <dbReference type="KEGG" id="mgr:MGG_01941"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01941"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_1_1"/>
    <dbReference type="InParanoid" id="G4NG04"/>
    <dbReference type="OMA" id="YWSLTAQ"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF53">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466599" evidence="5">
        <location>
            <begin position="25"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="65"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA46961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="520" mass="55621" checksum="5A3A049836FD45A3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGE5</accession>
    <name>G4NGE5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Potassium transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_04338</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719469.1">
        <property type="nucleotide sequence ID" value="XM_003719421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGE5"/>
    <dbReference type="STRING" id="242507.G4NGE5"/>
    <dbReference type="GeneID" id="2677581"/>
    <dbReference type="KEGG" id="mgr:MGG_04338"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04338"/>
    <dbReference type="eggNOG" id="KOG1341">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005947_4_1_1"/>
    <dbReference type="InParanoid" id="G4NGE5"/>
    <dbReference type="OMA" id="PHIITMR"/>
    <dbReference type="OrthoDB" id="9999863at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140107">
        <property type="term" value="F:high-affinity potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051143">
        <property type="entry name" value="TrkH_K-transport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064">
        <property type="entry name" value="POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064:SF37">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="464"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="162"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="233"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="825" mass="90479" checksum="4B53B88915B2061A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHH4</accession>
    <name>G4NHH4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2-oxoisovalerate dehydrogenase subunit alpha</fullName>
            <ecNumber evidence="9">1.2.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_03840</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the BCKDHA family.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="9"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720051.1">
        <property type="nucleotide sequence ID" value="XM_003720003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHH4"/>
    <dbReference type="SMR" id="G4NHH4"/>
    <dbReference type="STRING" id="242507.G4NHH4"/>
    <dbReference type="GeneID" id="2677190"/>
    <dbReference type="KEGG" id="mgr:MGG_03840"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03840"/>
    <dbReference type="eggNOG" id="KOG1182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029393_1_2_1"/>
    <dbReference type="InParanoid" id="G4NHH4"/>
    <dbReference type="OMA" id="GMFRGVN"/>
    <dbReference type="OrthoDB" id="3845at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:branched-chain 2-oxo acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02000">
        <property type="entry name" value="TPP_E1_PDC_ADC_BCADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000015">
        <property type="entry name" value="2-oxoisovalerate dehydrogenase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050771">
        <property type="entry name" value="Alpha-ketoacid_DH_E1_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="11">
        <location>
            <begin position="112"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA47684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="463" mass="52140" checksum="2366C88B5BC78DFF" modified="2011-12-14" version="1">MRVRLPGAASSIGRRCRNHGRGAPKIGSLHQTAPGSASSMRAASTLKQKPDSSFVSFPGAVKSEFTTKFQFERPEQYPAMPTYRVVDQHGVVVDPEFEQDLNDEGVIKLYEDMVAVSVMDSIMFDAQRQGRVSFYMVSAGEEAVCVGSASALEMRDVIFCQYREQGVYRHRGMTFRDFMNQLFANKYDPGQGRNMPVHYGSKELNMHTISSPLATQIPQASGAAYAMKMQRIANPDAPERVAVVYFGEGAASEGDFHAALNIAATRACPVIFICRNNGYSISTPSLEQYKGDGIASRGVGYGIDTVRVDGNDIWAVRKATKKARELALENGGKPVLLECLTYRVGHHSTSDDSFAYRARVEVEDWKRRDNPISRLRKWMESKDMWDDDKEKVMRDRLRKEILKAFSEAEKEKKPPIRAMFEDVYEEMTPDLKKQMAELKDHIERYPEEYDVGEFEGGKDSLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI37</accession>
    <name>G4NI37_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720264.1">
        <property type="nucleotide sequence ID" value="XM_003720216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI37"/>
    <dbReference type="SMR" id="G4NI37"/>
    <dbReference type="STRING" id="242507.G4NI37"/>
    <dbReference type="GeneID" id="2680429"/>
    <dbReference type="KEGG" id="mgr:MGG_09359"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09359"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_0_0_1"/>
    <dbReference type="InParanoid" id="G4NI37"/>
    <dbReference type="OMA" id="LENTWAL"/>
    <dbReference type="OrthoDB" id="5407715at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05188">
        <property type="entry name" value="MDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="2">
        <location>
            <begin position="38"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="1">
        <location>
            <begin position="203"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="378" mass="39963" checksum="FE15B0FCD7930010" modified="2011-12-14" version="1">MATTEENTALPATMKAVVLTGVNQPLELRTVPVPQVTPGSVIVKIICTSNDRGIQEAALGHARFTFPRPMIPTARAVGRVAQIGPDTTSLAPGQLVLVEPHVRARDDPDVQILWGMWDGPSAQSKKFARDNWTDACMAEYVRAPLENVYALDEAKLCGRLGHAPEDLVHLATLAILHGGLAAVGLRAGETVLVAPATGYFSGAAVPVALAMGAGAVVAVGRNAAALERLQATFGAERVRTVVTTGDVEADAAAMRKAAGPVDVYMDVSPPAASGSSHMRSGFKALGVGARAVLMGFVPDDIPLSYTEAMFKNLTVKGKYMYEREDMRGLIKMAESGVLKLGRAAGVEIIGRYKLEEYETMLHATSNNGDGSKLILTMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NII2</accession>
    <name>G4NII2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Extracelular serine carboxypeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_15423</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720409.1">
        <property type="nucleotide sequence ID" value="XM_003720361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NII2"/>
    <dbReference type="SMR" id="G4NII2"/>
    <dbReference type="MEROPS" id="S28.004"/>
    <dbReference type="GeneID" id="12987334"/>
    <dbReference type="KEGG" id="mgr:MGG_15423"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15423"/>
    <dbReference type="eggNOG" id="KOG2182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023630_0_0_1"/>
    <dbReference type="InParanoid" id="G4NII2"/>
    <dbReference type="OMA" id="MRQWYHQ"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000251">
        <property type="entry name" value="Extracelular serine carboxypeptidase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF117">
        <property type="entry name" value="SERINE PROTEASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466988" description="Extracelular serine carboxypeptidase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA48042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="564" mass="63828" checksum="8EACC084DC34A9F9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIJ4</accession>
    <name>G4NIJ4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720421.1">
        <property type="nucleotide sequence ID" value="XM_003720373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIJ4"/>
    <dbReference type="SMR" id="G4NIJ4"/>
    <dbReference type="STRING" id="242507.G4NIJ4"/>
    <dbReference type="GeneID" id="2680853"/>
    <dbReference type="KEGG" id="mgr:MGG_09820"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09820"/>
    <dbReference type="eggNOG" id="KOG2912">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027534_0_1_1"/>
    <dbReference type="InParanoid" id="G4NIJ4"/>
    <dbReference type="OMA" id="EHKIDNY"/>
    <dbReference type="OrthoDB" id="514248at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393:SF0">
        <property type="entry name" value="RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="54780" checksum="8ACBE4ED051AA725" modified="2011-12-14" version="1">MPAPVGVGVKRKRDAADTEVASDVQYSTSIENDSLKIPSAAATATVKDHGSAGYKEQQQEQIPKNDSYYRNLYRHEIDFREMGTQDPDFKAVLKRNGQLDFSDPKAVMQLTKSSLKLHFGLEMELPDDRLCPPVPNRHNYILWLKDLLDSSSYCPPGGKLTGLDIGTGASCIYPLLGCTQRPWEFIATDVDKKSLSYAEKNIAANNLSDRIKLVPRPDPATSPLIPLDELKIDAIDFVMTNPPFYESEKELLTLAAQKELPPSTACTGAPVEMVHLAGGEVGFVTRILDESLVLRERVRWYTSMLGKLSSLEVLVETLRDRGVTNYAVTEFVQGTKTKRWAVGWSFGGMRAGQAAARGMAQLAWRKVLPAPVEVEIGALGVSKAGEVAGNIDALMHGLELESWGWDKQELKGVARTRENVWGRAWRRRKAREKDGVGEASVGAAERDRPLSGFEVAMTVGRSQAVVVCRWREGHDEAIFQSFCGFLKTRLELGVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NK12</accession>
    <name>G4NK12_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10307</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720522.1">
        <property type="nucleotide sequence ID" value="XM_003720474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NK12"/>
    <dbReference type="STRING" id="242507.G4NK12"/>
    <dbReference type="GeneID" id="2681959"/>
    <dbReference type="KEGG" id="mgr:MGG_10307"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10307"/>
    <dbReference type="eggNOG" id="ENOG502QR47">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004835_2_1_1"/>
    <dbReference type="InParanoid" id="G4NK12"/>
    <dbReference type="OMA" id="FQHACAQ"/>
    <dbReference type="OrthoDB" id="4356994at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA45779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="753" mass="84667" checksum="1AA5A8CAA6C81CBE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4NK37</accession>
    <name>G4NK37_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_12670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721265.1">
        <property type="nucleotide sequence ID" value="XM_003721217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NK37"/>
    <dbReference type="SMR" id="G4NK37"/>
    <dbReference type="STRING" id="242507.G4NK37"/>
    <dbReference type="GeneID" id="5050542"/>
    <dbReference type="KEGG" id="mgr:MGG_12670"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12670"/>
    <dbReference type="eggNOG" id="ENOG502S5WK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098391_1_0_1"/>
    <dbReference type="InParanoid" id="G4NK37"/>
    <dbReference type="OMA" id="SRQEAQF"/>
    <dbReference type="OrthoDB" id="19690at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="24"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="189" mass="19820" checksum="81D23699BB887DBD" modified="2011-12-14" version="1">MVSSRPFLAAGRTLAGASKHLARKPTGVAFSTSHSAAAKNQVYSPIRSPSTFHTHLLSSSARMPLVTLWTTSWCPSCKHVEPLLKSVVESGVGEEHGGVGFALVELDAPDMQPSDLGLTYMINSVPTLLSFDGGDAQTATKVVDGRKLVNRQFLEEWVRNEASRQDRGGGGGGGIGGSGLLGGLFGSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL97</accession>
    <name>G4NL97_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_09604</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721485.1">
        <property type="nucleotide sequence ID" value="XM_003721437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL97"/>
    <dbReference type="STRING" id="242507.G4NL97"/>
    <dbReference type="GeneID" id="2680609"/>
    <dbReference type="KEGG" id="mgr:MGG_09604"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09604"/>
    <dbReference type="eggNOG" id="ENOG502SKG6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_6_1_1"/>
    <dbReference type="InParanoid" id="G4NL97"/>
    <dbReference type="OMA" id="ICICGID"/>
    <dbReference type="OrthoDB" id="2496787at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="55"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA46742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="398" mass="43841" checksum="D00079E8C273BF79" modified="2011-12-14" version="1">MPARDRRLQFKATSWALLGICIAAVLVRLMHKFAHGISGWRLGPDGQPVGAAPPGLDDLTFALSVATSIAFWVICICGIDPTIGNPIGTDLWTLSHDQVTQFIVMMLILEILYITNIFLLKTSFLLFYLRIFCRGGAGGGTVLGVDFGRVVQATMFVNGVVWIVTFMLVVFRCWPIQYQWTGWDRLQQGHCNMDAHPLVWAHAIVGLLIDIWMIYLPISQIWGMKMTLGKKLAVCSMFGVGAFATVVSILRLRLVFRASSDKRNSTWDDFDLILWSSLELGAGTFCACMPSLRHVFMAFIRRGADSLSGRTSCSSRISDRRSQPSEKGSRGRADTTASAKTCSETTTGSVSPSELEEGVIDHDRQVSGGRGWQGCCPPMSDRMVDDPISTSTSELRPS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2013-09-18" modified="2025-06-18" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>P0CT11</accession>
    <accession>A4RGF7</accession>
    <accession>G4NER8</accession>
    <accession>Q5G5B9</accession>
    <name>GPD_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber>1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ORF">MGG_00067</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction>
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="sequence caution" evidence="3">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="EHA49491" version="1"/>
        </conflict>
        <text>Extended N-terminus.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49491.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719075.1">
        <property type="nucleotide sequence ID" value="XM_003719027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P0CT11"/>
    <dbReference type="SMR" id="P0CT11"/>
    <dbReference type="FunCoup" id="P0CT11">
        <property type="interactions" value="571"/>
    </dbReference>
    <dbReference type="STRING" id="242507.P0CT11"/>
    <dbReference type="GeneID" id="2675060"/>
    <dbReference type="KEGG" id="mgr:MGG_00067"/>
    <dbReference type="eggNOG" id="KOG2711">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="P0CT11"/>
    <dbReference type="OrthoDB" id="10263760at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000004">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF8">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000138091" description="Glycerol-3-phosphate dehydrogenase [NAD(+)]">
        <location>
            <begin position="1"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="17"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="349"/>
            <end position="350"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="P21695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="433" mass="46756" checksum="AAFF086871BA1913" modified="2013-09-18" version="1">MASLGSYAKKHKVTIIGSGNWGSTIAKIVAESTREHKDVFEEDVQMWVFEEKVTIPKDSPYYESEEPQKLTEVINKHHENVKYLPGIKLPSNIIANPSLTDAVRDSSVLVFNLPHEFLGKVCQQLNGHIVPFARGISCIKGVDVSGSGINLFCEVIGEKLGIYCGALSGANVASQIAAEEGVSETTIAYDPPPIDSSRAATPRDRSPNYDSTSANKLPDLTVTSADSNGKDDRGRRTKAKLTPVPESYPPLDHGTLQILFDRPYFSVSMVSDVAGVSLSGALKNIVALAAGFVDGKGWGSNVQSAVIRVGLAEMLKFAREFFGESVDPFTILLESAGVADVITSCISGRNFRCASMAVKRGVSVAEIEEKELNGQKLQGTSTAKEVNSLLKARGREGDYPLFTTVNEILEGKARVDDLPKLVIRQKHTIEKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2006-03-07" modified="2025-10-08" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>Q2KEU2</accession>
    <accession>A4RAP9</accession>
    <name>Q2KEU2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Laccase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGCH7_ch7g944</name>
        <name evidence="12" type="ORF">MGG_09139</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15</strain>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845958.1">
        <property type="nucleotide sequence ID" value="XM_016990464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q2KEU2"/>
    <dbReference type="SMR" id="Q2KEU2"/>
    <dbReference type="STRING" id="242507.Q2KEU2"/>
    <dbReference type="GeneID" id="2680059"/>
    <dbReference type="KEGG" id="mgr:MGG_09139"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09139"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_3_2_1"/>
    <dbReference type="OMA" id="AIPQLDC"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13880">
        <property type="entry name" value="CuRO_2_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000021">
        <property type="entry name" value="Extracellular dihydrogeodin oxidase/laccase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000038">
        <property type="entry name" value="Extracellular dihydrogeodin oxidase/laccase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF502">
        <property type="entry name" value="MULTICOPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011098204" evidence="7">
        <location>
            <begin position="19"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="95"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="220"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="436"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EAQ71537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KYQ30454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="597" mass="65982" checksum="D24F710A637394A6" modified="2006-03-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2006-03-07" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>Q2KEU5</accession>
    <accession>A4RAQ2</accession>
    <name>Q2KEU5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g941</name>
        <name evidence="3" type="ORF">MGG_09137</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845961.1">
        <property type="nucleotide sequence ID" value="XM_016990462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q2KEU5"/>
    <dbReference type="GeneID" id="2680057"/>
    <dbReference type="KEGG" id="mgr:MGG_09137"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09137"/>
    <dbReference type="eggNOG" id="ENOG502TB0F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_868983_0_0_1"/>
    <dbReference type="OrthoDB" id="10494626at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KYQ30457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="320" mass="34455" checksum="B09BAB51808B963C" modified="2006-03-07" version="1">MFYAPATFEIFPNLFFRLEHSFCSAFAMMRHQWTFLLSGILISVCAARFLPPLSLERRSGRLLPRANIFVDMNEVKVGSTADTVSTMGLATCIGAVAYGTASRTSTNKVMVHATTAMVDAKLGEWSRAVNEAGIQNLRIFLSLPSPTLCDSIPDDKIIQDLQFMGKTANPGSIAEHRRAMNILLVKANRAAVVVADSLVPGPSRTVTRSNSRLGSPNPYGTMEATATHVLVEGTAVDTITPTPRQQQDASSMAPAPKATAGPETVPKKKQGSTPGQKPIVEPKKSVPNPKLVPGPGTKKTAISTKFPPKKGGMLRMFLRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4I4</accession>
    <name>A0A151V4I4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Antiviral helicase SKI2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_15042</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH165176">
        <property type="protein sequence ID" value="KYQ30491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845995.1">
        <property type="nucleotide sequence ID" value="XM_016990553.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A151V4I4"/>
    <dbReference type="FunCoup" id="A0A151V4I4">
        <property type="interactions" value="920"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A0A151V4I4"/>
    <dbReference type="GeneID" id="27922177"/>
    <dbReference type="KEGG" id="mgr:MGG_15042"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15042"/>
    <dbReference type="eggNOG" id="KOG0947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4I4"/>
    <dbReference type="OMA" id="DHVNIIM"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000354">
        <property type="entry name" value="ATP-dependent RNA helicase SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000001">
        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040801">
        <property type="entry name" value="Ski2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17911">
        <property type="entry name" value="Ski2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="336"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="619"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="536"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="545"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="557"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KYQ30491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1305" mass="144200" checksum="7F7AC76F3719D115" modified="2016-06-08" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4L5</accession>
    <name>A0A151V4L5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin 3 binding protein But2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_14179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165178">
        <property type="protein sequence ID" value="KYQ30521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846025.1">
        <property type="nucleotide sequence ID" value="XM_016990541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4L5"/>
    <dbReference type="GeneID" id="5049174"/>
    <dbReference type="KEGG" id="mgr:MGG_14179"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14179"/>
    <dbReference type="eggNOG" id="ENOG502SRT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4L5"/>
    <dbReference type="OMA" id="CNLVFDF"/>
    <dbReference type="OrthoDB" id="4657524at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018620">
        <property type="entry name" value="Ubiquitin3-bd_protein_But2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39613">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39613:SF1">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09792">
        <property type="entry name" value="But2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007590024" description="Ubiquitin 3 binding protein But2 C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin 3 binding protein But2 C-terminal" evidence="2">
        <location>
            <begin position="66"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KYQ30521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="223" mass="23927" checksum="7B8C1CB159C1C860" modified="2016-06-08" version="1">MAISSCSIEYKTTKMQLVTLLAFALPALAAPGVEQFRRPGASATQLNCPTNAVQEDGLLGDNYVKPALLLPFAASQPDRTFKPTTWATVTPNDRCTIFNLELPAEQTIGKNCSLVFDFPACDTSRYRFQGPGNFLFQPYAIGSGAVAGNTTYNNQPQKLGNLPDRQLLPGNSYVINTGSCEIPAGTPGQVTFAGSLCSPDSSLTFRQDDQQCPLGFFVLLSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>A4R9N3</accession>
    <name>A4R9N3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711273.1">
        <property type="nucleotide sequence ID" value="XM_003711225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R9N3"/>
    <dbReference type="GeneID" id="12986998"/>
    <dbReference type="KEGG" id="mgr:MGG_16609"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16609"/>
    <dbReference type="eggNOG" id="ENOG502T7AM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2606493_0_0_1"/>
    <dbReference type="InParanoid" id="A4R9N3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="79" mass="7158" checksum="34B002D2595BF5A5" modified="2007-05-15" version="1">MSSGGSNGTGRGGSSGSGGSSSGWNPILSHGSAIGILKPNVVFDVYGNSSSTGGSSSSSSSRGGSGGGGSSSSGSRGGR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-06-26" modified="2025-06-18" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RF61</accession>
    <accession>G4NC25</accession>
    <name>HSE1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Class E vacuolar protein-sorting machinery protein HSE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">HSE1</name>
        <name type="ORF">MGG_00455</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the STAM family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718612.1">
        <property type="nucleotide sequence ID" value="XM_003718564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RF61"/>
    <dbReference type="SMR" id="A4RF61"/>
    <dbReference type="FunCoup" id="A4RF61">
        <property type="interactions" value="345"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RF61"/>
    <dbReference type="EnsemblFungi" id="MGG_00455T0">
        <property type="protein sequence ID" value="MGG_00455T0"/>
        <property type="gene ID" value="MGG_00455"/>
    </dbReference>
    <dbReference type="GeneID" id="2674892"/>
    <dbReference type="KEGG" id="mgr:MGG_00455"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00455"/>
    <dbReference type="eggNOG" id="KOG2199">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010104_1_1_1"/>
    <dbReference type="InParanoid" id="A4RF61"/>
    <dbReference type="OMA" id="QVYRDWW"/>
    <dbReference type="OrthoDB" id="10255964at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21386">
        <property type="entry name" value="GAT_Hse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11805">
        <property type="entry name" value="SH3_GRB2_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16978">
        <property type="entry name" value="VHS_HSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050670">
        <property type="entry name" value="STAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC25 family.</text>
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
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                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
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                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_04478"/>
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    </dbReference>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051639">
        <property type="term" value="P:actin filament network formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044837">
        <property type="term" value="P:actomyosin contractile ring organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070649">
        <property type="term" value="P:formin-nucleated actin cable assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd21294">
        <property type="entry name" value="CH_FIMB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21300">
        <property type="entry name" value="CH_FIMB_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21303">
        <property type="entry name" value="CH_FIMB_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000042">
        <property type="entry name" value="Fimbrin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000010">
        <property type="entry name" value="Plastin-3 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000016">
        <property type="entry name" value="Probable fimbrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000027">
        <property type="entry name" value="Probable fimbrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039959">
        <property type="entry name" value="Fimbrin/Plastin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961:SF18">
        <property type="entry name" value="FI19014P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961">
        <property type="entry name" value="FIMBRIN/PLASTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="7">
        <location>
            <begin position="140"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="7">
        <location>
            <begin position="289"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="7">
        <location>
            <begin position="414"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="7">
        <location>
            <begin position="539"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00073963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA58368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="650" mass="72691" checksum="BD6406AAA134E310" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKN6</accession>
    <name>G4MKN6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06637</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709338.1">
        <property type="nucleotide sequence ID" value="XM_003709290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKN6"/>
    <dbReference type="SMR" id="G4MKN6"/>
    <dbReference type="GeneID" id="2684810"/>
    <dbReference type="KEGG" id="mgr:MGG_06637"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06637"/>
    <dbReference type="eggNOG" id="ENOG502STE2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139687_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKN6"/>
    <dbReference type="OMA" id="NPYRPGW"/>
    <dbReference type="OrthoDB" id="329272at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877:SF2">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="14"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="184" mass="19756" checksum="E9D8FBAB8C69D2E0" modified="2011-12-14" version="1">MAGPQASSSSSGRPLLRPAVAADVEHIRVLVDAAYSHYIARLGKEPGPMLENYGALVAQGKVTVCTTGQPVAAAAAVVTGRGEEEEQDHDREILGLLVLVPQTAEGAMLLDNVAVAPRAQGQGVGKLLMSFAEHRARQEGLSTVKLYTHVLMTENIGLYGRLGYRETGRVSEKGFDRVYMEKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML30</accession>
    <name>G4ML30_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Spo12-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711069.1">
        <property type="nucleotide sequence ID" value="XM_003711021.1"/>
    </dbReference>
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            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58457.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23996" checksum="4C3DC64D892C4F27" modified="2011-12-14" version="1">MFKFPRSSCALDDQGLLDLELHPNFEPSTRPYNTTHLHTNNQHLKTLDRIFLHHTSNFRKSIKDQPLQKNKRETLRATPATQQKTSTFKDTLKTPFTNKMSSAPLSDKDVNTSMSVNDKTHEVEKPGVKSMEYHRQVLASKMEEEKTKTYISPSDNIMSPCTAKLNAYRNKQVGKAKPKSLFAQASSRKLGGSNDGGLFGSSKSVPKTATPQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLF0</accession>
    <name>G4MLF0_PYRO7</name>
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        <submittedName>
            <fullName evidence="4">Ankyrin repeatl protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08651</name>
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    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003711035.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF11">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="541"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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            <end position="1125"/>
        </location>
    </feature>
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        <location>
            <begin position="1229"/>
            <end position="1261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA58471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1359" mass="150360" checksum="2CBA66C20AB956CB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMF3</accession>
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        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_15994</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708751.1">
        <property type="nucleotide sequence ID" value="XM_003708703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMF3"/>
    <dbReference type="GeneID" id="12985660"/>
    <dbReference type="KEGG" id="mgr:MGG_15994"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15994"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_379498_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMF3"/>
    <dbReference type="OrthoDB" id="163438at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
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    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055497">
        <property type="entry name" value="DUF7069"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054471">
        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031359">
        <property type="entry name" value="NACHT_N"/>
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    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23239">
        <property type="entry name" value="DUF7069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17100">
        <property type="entry name" value="NACHT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NWD NACHT-NTPase N-terminal" evidence="2">
        <location>
            <begin position="126"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="5">
        <location>
            <begin position="252"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7069" evidence="4">
        <location>
            <begin position="387"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="3">
        <location>
            <begin position="462"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA56139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="730" mass="83511" checksum="96231A5679A403EE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNH0</accession>
    <name>G4MNH0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L38e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_06952</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709696.1">
        <property type="nucleotide sequence ID" value="XM_003709648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNH0"/>
    <dbReference type="SMR" id="G4MNH0"/>
    <dbReference type="FunCoup" id="G4MNH0">
        <property type="interactions" value="860"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MNH0"/>
    <dbReference type="GeneID" id="2685125"/>
    <dbReference type="KEGG" id="mgr:MGG_06952"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06952"/>
    <dbReference type="eggNOG" id="KOG3499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152057_1_0_1"/>
    <dbReference type="InParanoid" id="G4MNH0"/>
    <dbReference type="OMA" id="RCHRFIY"/>
    <dbReference type="OrthoDB" id="10250488at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022618">
        <property type="term" value="P:protein-RNA complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.90:FF:000001">
        <property type="entry name" value="60S ribosomal protein L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_eL38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_eL38_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA57084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="81" mass="9295" checksum="6233E5A2CA6BED92" modified="2011-12-14" version="1">MPREVADIKKFIEICRRKDASSARIKKNKKSNQVKFKVRCQKNLYTLILKDAEKAEKLKQSLPPSLTVTEVSKSDKKSKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNI1</accession>
    <name>G4MNI1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromosome transmission fidelity protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_06961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709707.1">
        <property type="nucleotide sequence ID" value="XM_003709659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNI1"/>
    <dbReference type="GeneID" id="2685134"/>
    <dbReference type="KEGG" id="mgr:MGG_06961"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06961"/>
    <dbReference type="eggNOG" id="ENOG502S29P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053544_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNI1"/>
    <dbReference type="OMA" id="TGLFKFE"/>
    <dbReference type="OrthoDB" id="5329385at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031342">
        <property type="entry name" value="Mug163-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094:SF2">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17119">
        <property type="entry name" value="MMU163"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="31284" checksum="1048578C9DA9C849" modified="2011-12-14" version="1">MMVLVANMVVSTTTARPRVANLSTLRRLRAAVSAAARAAQAPRPATTAKLTTLQEANPRNLPEVWFRSTFPFGGPQPVMPNGRSPPPDPRKVKLGKTLRILQERLPTLLESPLPQEILAPNISLHLFPSTHQHLPAVSGRVAYIAALWTSPIAWNRVPLIGNNRLEILSERMVDQPIQSTPRRTGATGEQLVVRWRSLGGGNVLGLGSGDGDRSKEFVGLFIFDFDVEGRILSHTIETVQEGGHWEKGVGAKVVGLTDWLLGNIRRGGAPEGSLAAYHAPRIRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNP2</accession>
    <name>G4MNP2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_02101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708870.1">
        <property type="nucleotide sequence ID" value="XM_003708822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNP2"/>
    <dbReference type="SMR" id="G4MNP2"/>
    <dbReference type="GeneID" id="2681192"/>
    <dbReference type="KEGG" id="mgr:MGG_02101"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02101"/>
    <dbReference type="eggNOG" id="ENOG502SNAE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049749_2_1_1"/>
    <dbReference type="InParanoid" id="G4MNP2"/>
    <dbReference type="OMA" id="FDVITMN"/>
    <dbReference type="OrthoDB" id="6329284at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="31202" checksum="EE74DD292EEA5ED7" modified="2011-12-14" version="1">MTATDLDAENMASWVTNAQFWDDSIGAGGNVYWRKLQEPSLRRLVSAKIEAAKASAAGGRALDISTGNGLCARWLVDEGIPSVRAVDGSSGMIEVAKARMAEAKPRYDGIQIGLLDVTDRAAFAREIETAAEFGGYDVILMNMAIQDVPTLEPLVEALPKLLKKDGIFFGTLLHPVFLTSGAARDIKLTWVDGELVVERARIVKDYMSIPPYRGLAIPGQPAKQVYYHRNFQDLFAPFFQAGLVLDKLEELAFSEGDGEPDKIESTLNFTQIPVMMSFRVRRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP26</accession>
    <name>G4MP26_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein disulfide-isomerase</fullName>
            <ecNumber evidence="4">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_05688</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710587.1">
        <property type="nucleotide sequence ID" value="XM_003710539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP26"/>
    <dbReference type="SMR" id="G4MP26"/>
    <dbReference type="STRING" id="242507.G4MP26"/>
    <dbReference type="GeneID" id="2675946"/>
    <dbReference type="KEGG" id="mgr:MGG_05688"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05688"/>
    <dbReference type="eggNOG" id="KOG0190">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025879_0_1_1"/>
    <dbReference type="InParanoid" id="G4MP26"/>
    <dbReference type="OMA" id="WGLDVWQ"/>
    <dbReference type="OrthoDB" id="427280at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF132">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465429" description="protein disulfide-isomerase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA57975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="399" mass="43036" checksum="09517396B3CA4EB7" modified="2011-12-14" version="1">MQTCHLVILFVLPLSILGWNQISGSELEKALGSDGPKLIAFFNPTEPRSAGLEAEWLQAASEAPGSLLAVDCSNHENDNFCASHAGASYPAIRLFQDASPGSIYQGPKTAKPIINFLARHRRPLVSKLTTPDEYSALLTADEAVFIAYAPTQEQRALIQYAAVRYRDEFTFGLVANPALIPGEATESPPIPVVLCHRSNDAATSRLPLTEDSSTPKSSDDLAAFIEEASRPTIAELTVSTHARSLARGAPIVYIFAQTTAERASLRTSLHRLATGYRDSLTIVTVNPDEFPDLPGKLGLCGAAAGDEIVEGRPAGALHQLSKDRVYPYPRGRPVDPRSIQQWGLDVFQGRVKPWTPPGVTTSYDDLGPTRVAAAATRKISIANIPGLKIKIAGHRQDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP54</accession>
    <name>G4MP54_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708925.1">
        <property type="nucleotide sequence ID" value="XM_003708877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP54"/>
    <dbReference type="GeneID" id="5051788"/>
    <dbReference type="KEGG" id="mgr:MGG_14597"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14597"/>
    <dbReference type="HOGENOM" id="CLU_363715_0_0_1"/>
    <dbReference type="InParanoid" id="G4MP54"/>
    <dbReference type="OMA" id="DINGSHP"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="768" mass="74538" checksum="1AF4C25401F2609E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQE8</accession>
    <name>G4MQE8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710746.1">
        <property type="nucleotide sequence ID" value="XM_003710698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQE8"/>
    <dbReference type="SMR" id="G4MQE8"/>
    <dbReference type="STRING" id="242507.G4MQE8"/>
    <dbReference type="GeneID" id="12986429"/>
    <dbReference type="KEGG" id="mgr:MGG_16481"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16481"/>
    <dbReference type="eggNOG" id="KOG1432">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_884454_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQE8"/>
    <dbReference type="OMA" id="IWILRSH"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="165"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="290" mass="32305" checksum="190431C74BCD49DE" modified="2011-12-14" version="1">MASISYPIVTDLTVHFSSHSVSTCEPDSRTWHRIEKDLYLHTSDQRAWVYIALANEQELAAKDLLVMDIIVGDPPQNSKSSWERRPGGIWVRRGEFNGKIDDFVTEVDVLFGMDAVDPRPEWALIRSPIQLKCQADISVARLSILHGRAKLRPRATLRVRDDGKFRIVQISDTHMVTDVGLCKDAIDAHGNHLPWTEADPLTVKFIGEILDIEKPDLVVLTGDQLHHDICDSQSALFKVVAPIIERSIPFAAVFGNYDSEGTHALTLGSTSPTPLKSGPLEKCNDEIPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQN0</accession>
    <name>G4MQN0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I and III subunit RPAC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_09284</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709929.1">
        <property type="nucleotide sequence ID" value="XM_003709881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQN0"/>
    <dbReference type="SMR" id="G4MQN0"/>
    <dbReference type="FunCoup" id="G4MQN0">
        <property type="interactions" value="946"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MQN0"/>
    <dbReference type="GeneID" id="2680208"/>
    <dbReference type="KEGG" id="mgr:MGG_09284"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09284"/>
    <dbReference type="eggNOG" id="KOG1521">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038421_0_1_1"/>
    <dbReference type="InParanoid" id="G4MQN0"/>
    <dbReference type="OMA" id="KKKCRAF"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055029">
        <property type="term" value="C:nuclear DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07032">
        <property type="entry name" value="RNAP_I_II_AC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000003">
        <property type="entry name" value="Dna-directed rna polymerases i and iii subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033901">
        <property type="entry name" value="RNAPI/III_AC40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF13">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="7">
        <location>
            <begin position="64"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA57317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="373" mass="41639" checksum="CFC90C4567DEFC83" modified="2011-12-14" version="1">MPSQTSLSSEELNRRKLVGINKETVTNTISTDYPGAHYGEEHAWDVNEFSQHLNIQFHQNDPSLASFSLIGVDASIANAFRRIMIAEIPSLAIERVFITNNTSVIQDEVLAQRLGLVPLKGSKEGLRKFMKPFKRTETGGFDNSFDFNTVNLRLNVKCTRNPDAKPGENDPNKAYIKPNVYASDIEFVPAGQQTDYFSGDGAIVPVNPDILIAKLRPGQGIDLEMHAHIGYGWDHAKFSPVCTASYRLMPIIDIVKPIVGADAEKFRDCFPDGVIRLQPVTAAEAKEKGSGYEGHKGEMKAVVNDPMRDTVSRECLRHAEFEGKVKLGRRRDHFIFSIESAGQWDSDELFLASIAELKSKCKKLEEQVLNMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQR8</accession>
    <name>G4MQR8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secretory lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709967.1">
        <property type="nucleotide sequence ID" value="XM_003709919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQR8"/>
    <dbReference type="SMR" id="G4MQR8"/>
    <dbReference type="GeneID" id="5051174"/>
    <dbReference type="KEGG" id="mgr:MGG_14628"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14628"/>
    <dbReference type="eggNOG" id="ENOG502RPSG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029538_1_2_1"/>
    <dbReference type="InParanoid" id="G4MQR8"/>
    <dbReference type="OMA" id="PFRTIAW"/>
    <dbReference type="OrthoDB" id="5382058at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF1">
        <property type="entry name" value="LIPASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03583">
        <property type="entry name" value="LIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029171">
        <property type="entry name" value="Esterase_LipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465214" evidence="1">
        <location>
            <begin position="23"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="471" mass="50557" checksum="B7BD8BAC98F62243" modified="2011-12-14" version="1">MVSKLVSLFCLASAALVSTAQAQSQSQTSPSCDSVCQAQFRGAVTGEDANYVNLDITTDSFYQTPANISSYAVGDLVKSQDLDRATISRLWTLPAGMSMSRIYYVTEDIDGKPLPATAFALIPYSNPLGPDKPFRTIAWAHGTAGGNRQCAPSNQKAFEFDWEGPLALAQRGFVVIAPDYAGMGAEAPMGFMYEAGALHAHDVVHAIQAARQTSTLGPLMSKEWVVVGHSEGGLTAWRTAERQGMPDKAVDGLIGAVAAAPATRPLSLIPESFRRANGKPVGDAPSVIFLQSLGRLFPDQIKPADYFGQVALDRLALAKGRCLISDLALFSTLTADELYKDKSWLTHPTVVDWQNRYNGASGPKKLGTPLLVIQGEADELTYKEVAEKDFDDQCAALPDSAAEWSLYPGMGHDASMQAGQAEIVAWVNDRFDGKPTAGKCVKRTQKTATQRYSQVNPVWAALSARGPLPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS34</accession>
    <name>G4MS34_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Coatomer subunit beta'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_10504</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasmic vesicle</location>
            <location evidence="1 13">COPI-coated vesicle membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Golgi apparatus membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="13">The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the WD repeat COPB2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710112.1">
        <property type="nucleotide sequence ID" value="XM_003710064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS34"/>
    <dbReference type="SMR" id="G4MS34"/>
    <dbReference type="FunCoup" id="G4MS34">
        <property type="interactions" value="1266"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MS34"/>
    <dbReference type="GeneID" id="2682116"/>
    <dbReference type="KEGG" id="mgr:MGG_10504"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10504"/>
    <dbReference type="eggNOG" id="KOG0276">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005507_1_0_1"/>
    <dbReference type="InParanoid" id="G4MS34"/>
    <dbReference type="OMA" id="YVDYYPQ"/>
    <dbReference type="OrthoDB" id="10261470at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
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        <property type="entry name" value="Coatomer_WDAD_beta-like"/>
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        <property type="entry name" value="Coatomer alpha subunit, putative"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
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    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
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    <dbReference type="InterPro" id="IPR016453">
        <property type="entry name" value="COPB2"/>
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    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF2">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005567">
        <property type="entry name" value="Coatomer_beta'_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="Nitrous oxide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 13" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <keyword evidence="5 14" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="9"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="136"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="180"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="16">
        <location>
            <begin position="318"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="17">
        <location>
            <begin position="594"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="811"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="830"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA57500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="855" mass="95423" checksum="D9955A13CFBC5517" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT82</accession>
    <name>G4MT82_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hsp70-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_07156</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715354.1">
        <property type="nucleotide sequence ID" value="XM_003715306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT82"/>
    <dbReference type="SMR" id="G4MT82"/>
    <dbReference type="STRING" id="242507.G4MT82"/>
    <dbReference type="GeneID" id="2683139"/>
    <dbReference type="KEGG" id="mgr:MGG_07156"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07156"/>
    <dbReference type="eggNOG" id="KOG0101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009958_6_1_1"/>
    <dbReference type="InParanoid" id="G4MT82"/>
    <dbReference type="OMA" id="IYKHTME"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF82">
        <property type="entry name" value="FAMILY CHAPERONE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G08575)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA55547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="637" mass="71013" checksum="06DA15346CFC5AC5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTD9</accession>
    <name>G4MTD9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysophospholipase</fullName>
            <ecNumber evidence="6">3.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_01523</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the lysophospholipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="6"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714497.1">
        <property type="nucleotide sequence ID" value="XM_003714449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTD9"/>
    <dbReference type="SMR" id="G4MTD9"/>
    <dbReference type="STRING" id="242507.G4MTD9"/>
    <dbReference type="GeneID" id="2679737"/>
    <dbReference type="KEGG" id="mgr:MGG_01523"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01523"/>
    <dbReference type="eggNOG" id="KOG1325">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013227_1_0_1"/>
    <dbReference type="InParanoid" id="G4MTD9"/>
    <dbReference type="OMA" id="WALGRRF"/>
    <dbReference type="OrthoDB" id="6121437at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002642">
        <property type="entry name" value="LysoPLipase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728">
        <property type="entry name" value="CYTOSOLIC PHOSPHOLIPASE A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728:SF40">
        <property type="entry name" value="PATATIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01735">
        <property type="entry name" value="PLA2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00022">
        <property type="entry name" value="PLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51210">
        <property type="entry name" value="PLA2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLA2c" evidence="8">
        <location>
            <begin position="197"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="623"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="630"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="673"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA54690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="836" mass="93104" checksum="B9C10295E21E6668" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTT1</accession>
    <name>G4MTT1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF1740-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_04788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRDE2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713727.1">
        <property type="nucleotide sequence ID" value="XM_003713679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTT1"/>
    <dbReference type="STRING" id="242507.G4MTT1"/>
    <dbReference type="GeneID" id="2678020"/>
    <dbReference type="KEGG" id="mgr:MGG_04788"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04788"/>
    <dbReference type="eggNOG" id="KOG1972">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007550_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTT1"/>
    <dbReference type="OMA" id="MRDKELH"/>
    <dbReference type="OrthoDB" id="297219at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902369">
        <property type="term" value="P:negative regulation of RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013633">
        <property type="entry name" value="NRDE-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471:SF0">
        <property type="entry name" value="NUCLEAR EXOSOME REGULATOR NRDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08424">
        <property type="entry name" value="NRDE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="194"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA53920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1128" mass="126947" checksum="EE17005C051642F0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUH4</accession>
    <name>G4MUH4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipocalin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715473.1">
        <property type="nucleotide sequence ID" value="XM_003715425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUH4"/>
    <dbReference type="GeneID" id="2682999"/>
    <dbReference type="KEGG" id="mgr:MGG_07253"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07253"/>
    <dbReference type="HOGENOM" id="CLU_139323_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUH4"/>
    <dbReference type="OMA" id="HMSATIV"/>
    <dbReference type="OrthoDB" id="3904217at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024311">
        <property type="entry name" value="Lipocalin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13924">
        <property type="entry name" value="Lipocalin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipocalin-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="152" mass="16700" checksum="1B18821411CF4421" modified="2011-12-14" version="1">MKHDAILAVLAGTYTMINQTNPDSVRTWGDAPHGHITYTTHGFMSAVMASTNPEHRPPGITNSAEQQADPSLVADFATIAKHTMAYAAPYVVGEGSTTTSGVLVHGPLAVNTLPSFEGRMWTRWYTFYEGTDVLFLRLNETSEAGVWWRRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUQ5</accession>
    <name>G4MUQ5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="2">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_10204</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713835.1">
        <property type="nucleotide sequence ID" value="XM_003713787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUQ5"/>
    <dbReference type="SMR" id="G4MUQ5"/>
    <dbReference type="FunCoup" id="G4MUQ5">
        <property type="interactions" value="429"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUQ5"/>
    <dbReference type="GeneID" id="2681776"/>
    <dbReference type="KEGG" id="mgr:MGG_10204"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10204"/>
    <dbReference type="eggNOG" id="KOG1324">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_2_1_1"/>
    <dbReference type="InParanoid" id="G4MUQ5"/>
    <dbReference type="OMA" id="QYEFQMW"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046452">
        <property type="term" value="P:dihydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046655">
        <property type="term" value="P:folic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069:SF3">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00070">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="9">
        <location>
            <begin position="8"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="89"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="232" mass="25429" checksum="EF3B050C6E4E5F4A" modified="2011-12-14" version="1">MPPTSPIELTLVLAATRDMGIGRGGTLPWTGLKKEMAYFARVTKRLPAADDKPPTALNAVIMGRKTWDSIPPKFRPLKGRLNVVLSRSFPELKGTPPPPSSAAATTTTTTTTDPDPVVNDRVPIHARSLPEALAYLGQLREQRQAVGKVFIIGGAQIYDVALGLPETRRVLFTSVMSDFECDASVALRLGEGTGWRRTSKEEHDAWVGEEVPAGVQEENGTQYEFQMWERSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV05</accession>
    <name>G4MV05_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715546.1">
        <property type="nucleotide sequence ID" value="XM_003715498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV05"/>
    <dbReference type="SMR" id="G4MV05"/>
    <dbReference type="STRING" id="242507.G4MV05"/>
    <dbReference type="GeneID" id="12986701"/>
    <dbReference type="KEGG" id="mgr:MGG_15901"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15901"/>
    <dbReference type="eggNOG" id="ENOG502S60G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022139_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV05"/>
    <dbReference type="OMA" id="NSPIVDC"/>
    <dbReference type="OrthoDB" id="5388486at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039970">
        <property type="entry name" value="TF_Grauzone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23225:SF2">
        <property type="entry name" value="AT09679P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23225">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="390"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="709" mass="76865" checksum="AD957816C2A37BC5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVG7</accession>
    <name>G4MVG7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715600.1">
        <property type="nucleotide sequence ID" value="XM_003715552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVG7"/>
    <dbReference type="GeneID" id="12986712"/>
    <dbReference type="KEGG" id="mgr:MGG_15910"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15910"/>
    <dbReference type="HOGENOM" id="CLU_1875837_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVG7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="136" mass="15043" checksum="E001020818D0E3B7" modified="2011-12-14" version="1">MYHKVTKAPACMRKDVTTLTVAVKSFGGLIFTWSLGFCARRRSDSPVECLHLARQTTLKKPPPNRSADVMSKCPASVPLAYCAYLPFGPPALPVGSATISYGFGNSQGGTSLGICRSRRRNLSLHFRRYVWRQGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW50</accession>
    <name>G4MW50_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein disulfide-isomerase</fullName>
            <ecNumber evidence="5">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_08973</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="5"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714011.1">
        <property type="nucleotide sequence ID" value="XM_003713963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW50"/>
    <dbReference type="SMR" id="G4MW50"/>
    <dbReference type="STRING" id="242507.G4MW50"/>
    <dbReference type="GeneID" id="2679958"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08973"/>
    <dbReference type="eggNOG" id="KOG0190">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025879_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW50"/>
    <dbReference type="OMA" id="RAQPWDG"/>
    <dbReference type="OrthoDB" id="427280at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF132">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465691" description="Protein disulfide-isomerase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="12">
        <location>
            <begin position="26"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="333"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA54204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="370" mass="41478" checksum="C871FB954E53926D" modified="2011-12-14" version="1">MRLTTELQLILALAADVVFGWTHASEASLRKALRSNDYTLVAFVDSTHDASKSLEPQWIKIQTTERDNNVVSFDCGAKRKICDELDVVSYPAIRLYHQDGRMDRFRGPRTASEIVPFLRRALRPTISTLTDKNMTSFVGVDDVVFVAYLEKGDESLERRFLAQASGLRDRYSFAMGPPPEPGLRSTVACYNNREGDQRVHADFDGVGSLESFIEICAMPSIHEMNRRNELHLMQSGKSIVNYVFATDEDRELYVETMRQLAKKYTDYLVFTTINAEEYPDFGPNLGLGEGTGVSVMNPANGDVFPYLRAERISARSIDEFLIDIINGKVKPWGSEQEQQQVRNGGFQGRAAGSGKAASWTAHGTRMHGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWD2</accession>
    <name>G4MWD2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Enoyl reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_08363</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715699.1">
        <property type="nucleotide sequence ID" value="XM_003715651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWD2"/>
    <dbReference type="SMR" id="G4MWD2"/>
    <dbReference type="FunCoup" id="G4MWD2">
        <property type="interactions" value="224"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MWD2"/>
    <dbReference type="GeneID" id="2678539"/>
    <dbReference type="KEGG" id="mgr:MGG_08363"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08363"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_16_1_1"/>
    <dbReference type="InParanoid" id="G4MWD2"/>
    <dbReference type="OMA" id="HVATRKV"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF1">
        <property type="entry name" value="TRANS-ENOYL REDUCTASE STHE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="20"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="358" mass="37947" checksum="AF3BFBEC2C40BEBA" modified="2011-12-14" version="1">MSSSTVDLFTPPATQEGIVADSNGLPVVSTEAPCPPLNPDQVYVRTEAVAINPSDTKMVGDFVIPNALYGADYAGTVIAVGSHVQGIKAGERICGAQHSMHAGTPFNGAFGRFNVTNGHVWLKLPAGWSSEAGSTLGASVSTAGLAIRALGLPLPDEPLKVPAKVLVYGASTATGTIAIQLLKLANLVPIAVCSPKNFDLAKSRGAVEAFDYRDPECGDKIRTYTSSNLTYALDCITTVESTKACFRAIGRGGGRYVSLDPFQEHVATRKVVKTDWVLGPAIFGHGSTWPAPYMRPGDPELKEFGAKLWAVAQKLIDEGRLQHHPLHLLQGGFDMVIKGMELVKKGQVSGKKVVVRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWS1</accession>
    <name>G4MWS1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF747 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08332</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAPT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715732.1">
        <property type="nucleotide sequence ID" value="XM_003715684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWS1"/>
    <dbReference type="STRING" id="242507.G4MWS1"/>
    <dbReference type="GeneID" id="2678466"/>
    <dbReference type="KEGG" id="mgr:MGG_08332"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08332"/>
    <dbReference type="eggNOG" id="KOG2490">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003655_0_1_1"/>
    <dbReference type="InParanoid" id="G4MWS1"/>
    <dbReference type="OMA" id="TCCVLMY"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008010">
        <property type="entry name" value="Tatp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317:SF4">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05346">
        <property type="entry name" value="DUF747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="663"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="978"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="473"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="527"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA55925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1101" mass="119789" checksum="AD0864EEA484A38C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWU9</accession>
    <name>G4MWU9_PYRO7</name>
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        <recommendedName>
            <fullName evidence="1">Phosphoinositide phospholipase C</fullName>
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    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08315</name>
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    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715760.1">
        <property type="nucleotide sequence ID" value="XM_003715712.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MWU9"/>
    <dbReference type="SMR" id="G4MWU9"/>
    <dbReference type="GeneID" id="2678572"/>
    <dbReference type="KEGG" id="mgr:MGG_08315"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08315"/>
    <dbReference type="eggNOG" id="KOG0169">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_002738_3_0_1"/>
    <dbReference type="InParanoid" id="G4MWU9"/>
    <dbReference type="OMA" id="WAMNKFD"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="PHI-base" id="PHI:2019"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08598">
        <property type="entry name" value="PI-PLC1c_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056584">
        <property type="entry name" value="EF-hand_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF82">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
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        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="371"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        </location>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA55953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="649" mass="71994" checksum="243513830F0F1BDF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY53</accession>
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    <protein>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15658</name>
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    <organism evidence="1 2">
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714191.1">
        <property type="nucleotide sequence ID" value="XM_003714143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY53"/>
    <dbReference type="GeneID" id="12984610"/>
    <dbReference type="KEGG" id="mgr:MGG_15658"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15658"/>
    <dbReference type="HOGENOM" id="CLU_2776414_0_0_1"/>
    <dbReference type="InParanoid" id="G4MY53"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="69" mass="7934" checksum="AF72C0870DD14E4C" modified="2011-12-14" version="1">MEDGDQVNMSMFFWGTGYQETNPSPAMPYSPFPGRVHDNLKSWLDPQMLKSREALGSEATKHNPKDIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYV5</accession>
    <name>G4MYV5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisomal targeting signal receptor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Peroxin-5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_10840</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxisomal targeting signal receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713423.1">
        <property type="nucleotide sequence ID" value="XM_003713375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYV5"/>
    <dbReference type="SMR" id="G4MYV5"/>
    <dbReference type="FunCoup" id="G4MYV5">
        <property type="interactions" value="83"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYV5"/>
    <dbReference type="GeneID" id="2676364"/>
    <dbReference type="KEGG" id="mgr:MGG_10840"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10840"/>
    <dbReference type="eggNOG" id="KOG1125">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013516_3_0_1"/>
    <dbReference type="InParanoid" id="G4MYV5"/>
    <dbReference type="OMA" id="WEEQFKQ"/>
    <dbReference type="OrthoDB" id="10006023at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005052">
        <property type="term" value="F:peroxisome matrix targeting signal-1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000218">
        <property type="entry name" value="Peroxisomal targeting signal receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024111">
        <property type="entry name" value="PEX5/PEX5L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130:SF0">
        <property type="entry name" value="GH08708P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0882">Thioester bond</keyword>
    <keyword evidence="9 15" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0832">Ubl conjugation</keyword>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="360"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="513"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA53616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="650" mass="70655" checksum="A03D13AC0B5AD8EB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYV9</accession>
    <name>G4MYV9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713427.1">
        <property type="nucleotide sequence ID" value="XM_003713379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYV9"/>
    <dbReference type="SMR" id="G4MYV9"/>
    <dbReference type="STRING" id="242507.G4MYV9"/>
    <dbReference type="GeneID" id="2676361"/>
    <dbReference type="KEGG" id="mgr:MGG_10837"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10837"/>
    <dbReference type="eggNOG" id="KOG2483">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017046_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYV9"/>
    <dbReference type="OMA" id="MQHKQLS"/>
    <dbReference type="OrthoDB" id="8964853at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040112">
        <property type="entry name" value="WetA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22934">
        <property type="entry name" value="PROTEIN ESC1/WETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22934:SF23">
        <property type="entry name" value="ZF-C3H1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="339"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="495" mass="54390" checksum="CE66FE2F4965533D" modified="2011-12-14" version="1">MKMTEMDQRPATQKLPAGLAGVLNRPEEKRDSAYYSSTDSKHNSTTSCLGVGMLTPRDSTGAPPSAHTNSNTPSPSPISTSTNLMPQPLVSPSTSNMSVASMVSPTTPVSIDHRRHERPQSLESAPNGNHWNGEHLDQPVSRRESVDSRILNQGIGDMRLGNSPYTSHNPSTTSIQNTLLQQRNPRPAHLDSLSIHRISNGYQPSNDRTPDLHPKIARTAPAITGPATGNIARAAEPTKGQAWAFPEEEIQRLPSASQSLVDSRRSSVAESLASSQFTTESRLPPGQRHLDDGLHQSERFSNEYPVVHHHTLQHKQIGELQGDAAGLAPGSQPYSRTPELRRSHKLAERKRRTEMKELFEELRDLMPQERGSKASKWEILTKAIAEHKRQADTLRSLHQTNGSLHQELEAMRRDVMALRGENTQLRNELATASNSHHGVGGLPNLSSQNGGDGYGRATSLRQELPPLRSLNNGMPGPPDTMTGVQYEQPRANGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYY7</accession>
    <name>G4MYY7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sialidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713455.1">
        <property type="nucleotide sequence ID" value="XM_003713407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYY7"/>
    <dbReference type="STRING" id="242507.G4MYY7"/>
    <dbReference type="GeneID" id="5051361"/>
    <dbReference type="KEGG" id="mgr:MGG_11410"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11410"/>
    <dbReference type="eggNOG" id="ENOG502R6VZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020422_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYY7"/>
    <dbReference type="OMA" id="PTRGMHD"/>
    <dbReference type="OrthoDB" id="5300765at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="615" mass="66686" checksum="17077182E71C5936" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ15</accession>
    <name>G4MZ15_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714290.1">
        <property type="nucleotide sequence ID" value="XM_003714242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ15"/>
    <dbReference type="GeneID" id="12984631"/>
    <dbReference type="KEGG" id="mgr:MGG_15678"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15678"/>
    <dbReference type="HOGENOM" id="CLU_2400105_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ15"/>
    <dbReference type="OrthoDB" id="68104at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="93" mass="10177" checksum="B35E89BFEB2E7920" modified="2011-12-14" version="1">MMDLGSVGSQFTAVHGDHGEAQPSKQMQTAKEVKMYPSPRCSCRCLSTLDAIAFYHATRLQPSSSNHHQTSATLCASQPLPAKNIPTFTLDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ60</accession>
    <name>G4MZ60_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_08168</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715140.1">
        <property type="nucleotide sequence ID" value="XM_003715092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ60"/>
    <dbReference type="SMR" id="G4MZ60"/>
    <dbReference type="STRING" id="242507.G4MZ60"/>
    <dbReference type="GeneID" id="2678372"/>
    <dbReference type="KEGG" id="mgr:MGG_08168"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08168"/>
    <dbReference type="eggNOG" id="ENOG502SM93">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011409_2_0_1"/>
    <dbReference type="InParanoid" id="G4MZ60"/>
    <dbReference type="OMA" id="QECHFEP"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF4">
        <property type="entry name" value="HYPOTHETICAL CONSERVED PROTEIN (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="597"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="613"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="650"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="717" mass="79588" checksum="4F6EBB01A411C48A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZR7</accession>
    <name>G4MZR7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07058</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EHA55431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="SMR" id="G4MZR7"/>
    <dbReference type="FunCoup" id="G4MZR7">
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    </dbReference>
    <dbReference type="STRING" id="242507.G4MZR7"/>
    <dbReference type="GeneID" id="2682943"/>
    <dbReference type="KEGG" id="mgr:MGG_07058"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07058"/>
    <dbReference type="eggNOG" id="KOG0562">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066882_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZR7"/>
    <dbReference type="OMA" id="IHDMFPK"/>
    <dbReference type="OrthoDB" id="3512845at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033699">
        <property type="term" value="F:DNA 5'-adenosine monophosphate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990165">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:single strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032566">
        <property type="entry name" value="Znf-C2HE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF4">
        <property type="entry name" value="APRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16278">
        <property type="entry name" value="zf-C2HE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HIT" evidence="7">
        <location>
            <begin position="75"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Aprataxin C2HE/C2H2/C2HC zinc finger" evidence="8">
        <location>
            <begin position="214"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="273" mass="31367" checksum="DA12579256981533" modified="2011-12-14" version="1">MAAPWNRPDLKRKREARIQELLDKSSQPKRQNHVIPGATTDDKIKTMERLRKKYPGANGLGMYIEEPEAFPAFRNVIYYNDDFVAVRDIYPKSSVHLLLLPRSEVHSKMHPVTALSTDAEFLAKVRDEAVTLKRIVASELRRMYGEESASEAERTRALLDPSSVDELPKGRDWEAGIKVGVHATPSMNHLHVHFMSPDNVGGSMKKAHHYMSFNTGFLVRLEEFPLAKEDPRWKGGQAYLSQQMTCWRCPESFTSFGKLKSHLLQEFEEWKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZV8</accession>
    <name>G4MZV8_PYRO7</name>
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        <recommendedName>
            <fullName evidence="13">Multicopper oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_09103</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711209.1">
        <property type="nucleotide sequence ID" value="XM_003711161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZV8"/>
    <dbReference type="SMR" id="G4MZV8"/>
    <dbReference type="GeneID" id="2680090"/>
    <dbReference type="KEGG" id="mgr:MGG_09103"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09103"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_5_1_1"/>
    <dbReference type="InParanoid" id="G4MZV8"/>
    <dbReference type="OMA" id="GSEFYCY"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13876">
        <property type="entry name" value="CuRO_2_Abr2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF488">
        <property type="entry name" value="LACCASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="84"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="251"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="528"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA51402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="676" mass="73053" checksum="5FC6DD24075358F1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2020-06-17" modified="2025-06-18" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZY8</accession>
    <name>RAS2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Ras-like protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">RAS2</name>
        <name type="ORF">MGG_06154</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2006" name="Plant Cell" volume="18" first="2822" last="2835">
            <title>Multiple upstream signals converge on the adaptor protein Mst50 in Magnaporthe grisea.</title>
            <authorList>
                <person name="Park G."/>
                <person name="Xue C."/>
                <person name="Zhao X."/>
                <person name="Kim Y."/>
                <person name="Orbach M."/>
                <person name="Xu J.R."/>
            </authorList>
            <dbReference type="PubMed" id="17056708"/>
            <dbReference type="DOI" id="10.1105/tpc.105.038422"/>
        </citation>
        <scope>INTERACTION WITH MST50</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2014" name="Mol. Plant Microbe Interact." volume="27" first="996" last="1004">
            <title>Bypassing both surface attachment and surface recognition requirements for appressorium formation by overactive ras signaling in Magnaporthe oryzae.</title>
            <authorList>
                <person name="Zhou X."/>
                <person name="Zhao X."/>
                <person name="Xue C."/>
                <person name="Dai Y."/>
                <person name="Xu J.R."/>
            </authorList>
            <dbReference type="PubMed" id="24835254"/>
            <dbReference type="DOI" id="10.1094/mpmi-02-14-0052-r"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>MUTAGENESIS OF GLY-18</scope>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2019" name="Mol. Plant Pathol." volume="20" first="1264" last="1278">
            <title>The farnesyltransferase beta-subunit RAM1 regulates localization of RAS proteins and appressorium-mediated infection in Magnaporthe oryzae.</title>
            <authorList>
                <person name="Aboelfotoh Hendy A."/>
                <person name="Xing J."/>
                <person name="Chen X."/>
                <person name="Chen X.L."/>
            </authorList>
            <dbReference type="PubMed" id="31250536"/>
            <dbReference type="DOI" id="10.1111/mpp.12838"/>
        </citation>
        <scope>SUBCELLULAR LOCATION</scope>
        <scope>INTERACTION WITH RAM1</scope>
        <scope>MUTAGENESIS OF CYS-211</scope>
        <scope>ISOPRENYLATION AT CYS-211</scope>
    </reference>
    <comment type="function">
        <text evidence="2 5">Modulates the activity of the adenylate cyclase catalytic subunit and therefore affects the biosynthesis of cyclic-AMP (By similarity). Plays a role in both surface attachment and surface recognition of appressoria, a highly specialized infection structure for plant penetration. Regulates appressorium formation by coordinated regulation of cAMP signaling and Pmk1 MAPK pathways (PubMed:24835254).</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="2">Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with farnesyltransferase beta subunit RAM1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Lipid-anchor</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712033.1">
        <property type="nucleotide sequence ID" value="XM_003711985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZY8"/>
    <dbReference type="SMR" id="G4MZY8"/>
    <dbReference type="FunCoup" id="G4MZY8">
        <property type="interactions" value="470"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZY8"/>
    <dbReference type="EnsemblFungi" id="MGG_06154T0">
        <property type="protein sequence ID" value="MGG_06154T0"/>
        <property type="gene ID" value="MGG_06154"/>
    </dbReference>
    <dbReference type="GeneID" id="2684336"/>
    <dbReference type="KEGG" id="mgr:MGG_06154"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06154"/>
    <dbReference type="eggNOG" id="KOG0395">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_9_8_1"/>
    <dbReference type="InParanoid" id="G4MZY8"/>
    <dbReference type="OMA" id="CCGGCVI"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04138">
        <property type="entry name" value="H_N_K_Ras_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000080">
        <property type="entry name" value="Ras-like GTPase Ras1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0449">Lipoprotein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0636">Prenylation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000449941" description="Ras-like protein 2">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="propeptide" id="PRO_0000449942" description="Removed in mature form" evidence="2">
        <location>
            <begin position="212"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Effector region" evidence="2">
        <location>
            <begin position="38"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="19"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="35"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="65"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="122"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Cysteine methyl ester" evidence="2">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="S-farnesyl cysteine" evidence="10">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Dominant active allele; bypasses surface attachment for appressorium formation and forms abnormal appresoria on hydrophilic surfaces." evidence="5">
        <original>G</original>
        <variation>V</variation>
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Prevents farnesylation and restricts subcellular location to the cytoplasm in appressorium, mycelium, conidium and infection hyphae." evidence="6">
        <original>C</original>
        <variation>S</variation>
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="P01112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="P01120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="4">
        <source>
            <dbReference type="PubMed" id="15846337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="24835254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="6">
        <source>
            <dbReference type="PubMed" id="31250536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="7">
        <source>
            <dbReference type="PubMed" id="17056708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="8">
        <source>
            <dbReference type="PubMed" id="24835254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="9"/>
    <evidence type="ECO:0000305" key="10">
        <source>
            <dbReference type="PubMed" id="31250536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA52226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="214" mass="24098" checksum="6671462789321B93" modified="2011-12-14" version="1" precursor="true">MAQSKFLREYKLVVVGGGGVGKSCLTIQLIQSHFVDEYDPTIEDSYRKQCVIDDEVALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYSITSRQSFEEITTFQQQILRVKDKDYFPMVVVGNKCDLEGEREVTRQEGEALARSFNCKFIETSAKSRINVDKAFYDIVREIRRYNREMQGYSTGSGGSNAGGPSNKMEVNDSDAEAGCCSKCVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N018</accession>
    <name>G4N018_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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            <end position="35"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003712024.1"/>
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        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
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        <property type="entry name" value="RBM17"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA52265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="457" mass="50006" checksum="96495FF2BD01162F" modified="2011-12-14" version="1">MLRFQPMRRPQPGQKPKPKGAFLKIGAITAPATTTPAAATATPTVASSTSADPSAASAPVQQPPRSKLADWAATEDDEYAYGLGKRHRGGRKAKKKNNRDDTDRETDWDELYDPARPTNVEEYLRSDERIAEIREWKGVLYAHRRRREQNRIRSRSRGSRGSSSGSEARAPHTNQFAPPPQYSFVPPQPSPPRVQKQSAMTVVADDATGDDAYARRLALSKVKEVETPPPQPDAVPAATISRAPVRYEPTPLPNEDGEDMDIDEDEGERPGLGSAKPKDSDDVRSNRPGQAGFAARMMEKMGWEKGKGLGAEETGITSGLSVKVEKRRKRPDAEGGGFASPGNMARVVGGNRGVQDVGKFGSMSEVVALGGMLEGMEDVAGEVAEGLAQEIGEECGEKYGRVERLYVDVNTRQVFIKFTDQVSALRAVNALDGRIFNGNEVRPRFYDLERFEQGVYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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            <taxon>Pyricularia</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712918.1">
        <property type="nucleotide sequence ID" value="XM_003712870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N076"/>
    <dbReference type="SMR" id="G4N076"/>
    <dbReference type="STRING" id="242507.G4N076"/>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="GeneID" id="2683642"/>
    <dbReference type="KEGG" id="mgr:MGG_07715"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07715"/>
    <dbReference type="eggNOG" id="ENOG502S39Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077989_1_0_1"/>
    <dbReference type="InParanoid" id="G4N076"/>
    <dbReference type="OMA" id="YDISAEF"/>
    <dbReference type="OrthoDB" id="4524534at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000387">
        <property type="entry name" value="Galactan endo-beta-1,3-galactanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465590" description="GH16 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="33"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="258" mass="28501" checksum="F45F018892C9CE7B" modified="2011-12-14" version="1">MFNSIPHFLLMTSGVGIALMPQVMAVRTMIPCTSFDNQSNFDADWNYNYPWGTDHNGAARMDGANAVRLASRGDRTLVITARRAEGLPPATHGGQQIPIRYLSGAIHAKEQFTVRPNGGYDFTGEFKATTTKGTWPAFWLTGVDSWPPEIDMAEWKGSGKISFNTFNTSSEVVSRDVDYPAPDQFHSIKCEVRDEGQDVRANFYMDGNLLTTQIGKGYVGKPLFLIINLQMEGSSGTPGPESDTEYAIRNLEVLSYNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N189</accession>
    <name>G4N189_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GOLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_07471</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711375.1">
        <property type="nucleotide sequence ID" value="XM_003711327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N189"/>
    <dbReference type="SMR" id="G4N189"/>
    <dbReference type="FunCoup" id="G4N189">
        <property type="interactions" value="58"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N189"/>
    <dbReference type="GeneID" id="2683391"/>
    <dbReference type="KEGG" id="mgr:MGG_07471"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07471"/>
    <dbReference type="eggNOG" id="KOG1693">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066963_4_2_1"/>
    <dbReference type="InParanoid" id="G4N189"/>
    <dbReference type="OMA" id="VGEYTFC"/>
    <dbReference type="OrthoDB" id="1929172at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465933" description="GOLD domain-containing protein" evidence="10">
        <location>
            <begin position="21"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="11">
        <location>
            <begin position="32"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA51568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="210" mass="23530" checksum="41EB0EFB5B9F7F7A" modified="2011-12-14" version="1">MQLLLFTYGLFAWLAAQAAATALTYKLHASEKACFYTAGKTKGEKIAFYFAVQSGGSFDVDYEVIGPTGKVILDGEAERQGDFVFTVNDIGEYRFCFSNTMSSYDDKVIDFEIAVENEARVGLPSKKGTSPEQTTTLEESAFKISGQLSSITRHQKYFRTRENRNFATVRSTEKRIINFSLIQCGLIVLMGALQVFIVRFFFQGARKGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1B5</accession>
    <name>G4N1B5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09548</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712193.1">
        <property type="nucleotide sequence ID" value="XM_003712145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1B5"/>
    <dbReference type="GeneID" id="2680446"/>
    <dbReference type="KEGG" id="mgr:MGG_09548"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09548"/>
    <dbReference type="eggNOG" id="ENOG502S3JP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090055_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1B5"/>
    <dbReference type="OMA" id="MSWFTEM"/>
    <dbReference type="OrthoDB" id="2107166at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <source>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
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                <person name="Kim S."/>
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                <person name="Bohnert H."/>
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                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003713120.1"/>
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    <dbReference type="KEGG" id="mgr:MGG_07924"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07924"/>
    <dbReference type="HOGENOM" id="CLU_776278_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2F6"/>
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        <property type="component" value="Chromosome 3"/>
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    <proteinExistence type="predicted"/>
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        </location>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="357" mass="39710" checksum="3FEBA155F4FAC1BE" modified="2011-12-14" version="1">MRTQTFAAFLLTAALPAIVAALPTNIPNTQLTSAPAFEARSTHDIEDISLAKRSEVVARQEGGQPEYDIYESDMDGLEGPEQASHQFGGEEPEDFEDLMNGQVDFSKFQEQMLQRQDEELRDEERRQKDSNWEGPLEDGEPFGMKSVPEEPFDFDFNILEARSDEAPSPDMGLVVDEQVPTRFRRRHEGHGDGHETNDEGAEPEQAHSGNVDGHETDVEGAEPEEAHAGHGDEPHDDEDTVEEEDEMVERRQLGHIAEDEGDDDEDDAFAGLDMSAHAGDDEDGDDDEEEALVDEDYEDAEYEEDGFGLDRRDLPGVNNGAADSSIIIEKREVGTEQTTTPPPPIAIERRVARSFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2K8</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <gene>
        <name evidence="2" type="ORF">MGG_07605</name>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003711476.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="mgr:MGG_07605"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07605"/>
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    <dbReference type="InParanoid" id="G4N2K8"/>
    <dbReference type="OrthoDB" id="5230921at2759"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="176"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="120"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="176" mass="20016" checksum="53CE6CB4196C35EE" modified="2011-12-14" version="1">MAPNDEKKRLVTEQPEPLDYHDMHYMDDMGKMDVDAELFCQYMGCIPENNLGIWYPRASDAFLHWANEHRRGGWHSPATRAEAQGVAAARQDRHRHNIPADTRSSRVRLELVKRTGEQGRRQQRCLHKPEQPSRLRQEMVPDELEGEGGNKSHGAASASTPVEPVLENPSSGLKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003711542.1">
        <property type="nucleotide sequence ID" value="XM_003711494.1"/>
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    <dbReference type="AlphaFoldDB" id="G4N2M6"/>
    <dbReference type="GeneID" id="12984134"/>
    <dbReference type="KEGG" id="mgr:MGG_16667"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16667"/>
    <dbReference type="HOGENOM" id="CLU_2413682_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2M6"/>
    <dbReference type="OrthoDB" id="5238391at2759"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="92" mass="10010" checksum="08ABCBCB29C70E45" modified="2011-12-14" version="1">MHPSITSPITLAQQQQQKQQQQQQQHSVSAITVGMSTTFWSAVGSAARFGMAVAVVATTVASFSSRVMGDDEDPLSLAIWTEEEGDAWWMIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2P3</accession>
    <name>G4N2P3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12974</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003712307.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_12974"/>
    <dbReference type="HOGENOM" id="CLU_1713632_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2P3"/>
    <dbReference type="OMA" id="QKTITAH"/>
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        <property type="component" value="Chromosome 3"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="153" mass="16432" checksum="BC334E1FAB4FF6BF" modified="2011-12-14" version="1">MSTAIPVPSSPSFGPCQSLVFNPLPLGHYQQHDQRHKQHQSSAESMHHQQKIAARPALQHQCAYWDKTQKTITAHPEAPLCGQHCSSGIAESCTQKENKASSGGKRAQELVPPPRLEIRGKDVDDKALISPLMLSESPRRATAAGGIAGGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N341</accession>
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        <recommendedName>
            <fullName evidence="3">Nephrocystin 3-like N-terminal domain-containing protein</fullName>
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    </protein>
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        <name evidence="4" type="ORF">MGG_16825</name>
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    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003712356.1"/>
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    <dbReference type="AlphaFoldDB" id="G4N341"/>
    <dbReference type="SMR" id="G4N341"/>
    <dbReference type="STRING" id="242507.G4N341"/>
    <dbReference type="GeneID" id="12985018"/>
    <dbReference type="KEGG" id="mgr:MGG_16825"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16825"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_346160_0_0_1"/>
    <dbReference type="InParanoid" id="G4N341"/>
    <dbReference type="OMA" id="EREHSHE"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
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    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
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    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
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    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
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    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="18"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="628"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="695"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="737" mass="82732" checksum="54B25E1FDEA23631" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3F7</accession>
    <name>G4N3F7_PYRO7</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16692</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711642.1">
        <property type="nucleotide sequence ID" value="XM_003711594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3F7"/>
    <dbReference type="STRING" id="242507.G4N3F7"/>
    <dbReference type="GeneID" id="12984166"/>
    <dbReference type="KEGG" id="mgr:MGG_16692"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16692"/>
    <dbReference type="eggNOG" id="ENOG502T6SS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156704_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3F7"/>
    <dbReference type="OMA" id="TQARICY"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="95" mass="10415" checksum="D8D0F7A26B5E3382" modified="2011-12-14" version="1">MAVNALTQARICYQCLFESCSLHLLPRLPVARITRLAIDNNHPPVPSSPHLLGTSSPWLQTTDSSAVWTQAPLDEEPSTAVRRILRAPEGTGSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4M4</accession>
    <name>G4N4M4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711846.1">
        <property type="nucleotide sequence ID" value="XM_003711798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4M4"/>
    <dbReference type="STRING" id="242507.G4N4M4"/>
    <dbReference type="GeneID" id="2683975"/>
    <dbReference type="KEGG" id="mgr:MGG_06000"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06000"/>
    <dbReference type="eggNOG" id="ENOG502S2WW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123426_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4M4"/>
    <dbReference type="OMA" id="LNWWGTR"/>
    <dbReference type="OrthoDB" id="2344991at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013879">
        <property type="entry name" value="DUF1761"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40638">
        <property type="entry name" value="UPF0591 MEMBRANE PROTEIN C15E1.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40638:SF1">
        <property type="entry name" value="UPF0591 MEMBRANE PROTEIN C15E1.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08570">
        <property type="entry name" value="DUF1761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="150" mass="15811" checksum="FC1A8337651FD0CF" modified="2011-12-14" version="1">MSLHYLPPVKPSAIALGTVFCQTAELAVLTPIFGATYNRAKAANTKEEFLRSKEASSAGIAWGTSLVGSALQSYGVGALINATATLSYKGSAYLGALIFMATSAPGYISQVFLEKRPLETVGVSVVAKVMETVGLACVLTWWGTRTNPFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5X2</accession>
    <name>G4N5X2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA49748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003716067.1">
        <property type="nucleotide sequence ID" value="XM_003716019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5X2"/>
    <dbReference type="GeneID" id="2678676"/>
    <dbReference type="KEGG" id="mgr:MGG_08552"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08552"/>
    <dbReference type="HOGENOM" id="CLU_2097338_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5X2"/>
    <dbReference type="OMA" id="GHYAKKP"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
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            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="116" mass="11745" checksum="037E6B91E2284E68" modified="2011-12-14" version="1">MSSTTSHVSANGQTTHSQSTVSHTPAPPSTGTSHAYAAALALGPAMPWSGEAYKAMTARKPGHYAKKPQHKTGSSSSSGWRSLLKGSSAGKKKAADAEAHAAAAKLGGDEDSVYGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6X7</accession>
    <name>G4N6X7_PYRO7</name>
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        <submittedName>
            <fullName evidence="11">WD repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_06500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
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    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat NOL10/ENP2 family.</text>
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        <property type="protein sequence ID" value="EHA50741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003717012.1"/>
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    <dbReference type="AlphaFoldDB" id="G4N6X7"/>
    <dbReference type="SMR" id="G4N6X7"/>
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    </dbReference>
    <dbReference type="STRING" id="242507.G4N6X7"/>
    <dbReference type="GeneID" id="2684655"/>
    <dbReference type="KEGG" id="mgr:MGG_06500"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06500"/>
    <dbReference type="eggNOG" id="KOG2321">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_009923_0_1_1"/>
    <dbReference type="InParanoid" id="G4N6X7"/>
    <dbReference type="OMA" id="GYFMDVR"/>
    <dbReference type="OrthoDB" id="273340at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR056551">
        <property type="entry name" value="Beta-prop_NOL10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040382">
        <property type="entry name" value="NOL10/Enp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056550">
        <property type="entry name" value="NOL10_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012580">
        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14927">
        <property type="entry name" value="NUCLEOLAR PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14927:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23098">
        <property type="entry name" value="Beta-prop_NOL10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23097">
        <property type="entry name" value="NOL10_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08159">
        <property type="entry name" value="NUC153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Nucleolar protein 10-like N-terminal" evidence="10">
        <location>
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            <end position="381"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="239"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleolar protein 10-like second" evidence="9">
        <location>
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            <end position="435"/>
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    </feature>
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        <location>
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            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005264"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA50741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="636" mass="71434" checksum="3542644142E25A7B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7I3</accession>
    <name>G4N7I3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">mRNA-decapping enzyme 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_06410</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717159.1">
        <property type="nucleotide sequence ID" value="XM_003717111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7I3"/>
    <dbReference type="SMR" id="G4N7I3"/>
    <dbReference type="STRING" id="242507.G4N7I3"/>
    <dbReference type="GeneID" id="2684565"/>
    <dbReference type="KEGG" id="mgr:MGG_06410"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06410"/>
    <dbReference type="eggNOG" id="KOG2937">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008108_4_0_1"/>
    <dbReference type="InParanoid" id="G4N7I3"/>
    <dbReference type="OMA" id="HYHHITA"/>
    <dbReference type="OrthoDB" id="18996at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1050:FF:000003">
        <property type="entry name" value="Decapping enzyme Dcp2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000003">
        <property type="entry name" value="M7GpppN-mRNA hydrolase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1050">
        <property type="entry name" value="Dcp2, box A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007722">
        <property type="entry name" value="DCP2_BoxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036189">
        <property type="entry name" value="DCP2_BoxA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05026">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01125">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140586">
        <property type="entry name" value="Dcp2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="95"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="313"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="471"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="617"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="693"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="803"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="617"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="810"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA50840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="848" mass="91482" checksum="C57B2455C7BFD76A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>G4N845</accession>
    <name>G4N845_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_06320</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717265.1">
        <property type="nucleotide sequence ID" value="XM_003717217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N845"/>
    <dbReference type="SMR" id="G4N845"/>
    <dbReference type="FunCoup" id="G4N845">
        <property type="interactions" value="272"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N845"/>
    <dbReference type="GeneID" id="2684475"/>
    <dbReference type="KEGG" id="mgr:MGG_06320"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06320"/>
    <dbReference type="eggNOG" id="KOG0578">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_26_2_1"/>
    <dbReference type="InParanoid" id="G4N845"/>
    <dbReference type="OMA" id="NFTHRVH"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000910">
        <property type="term" value="P:negative regulation of sterol import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019236">
        <property type="term" value="P:response to pheromone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035376">
        <property type="term" value="P:sterol import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000139">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000356">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000535">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.810.10:FF:000005">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="CRIB_dom"/>
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        <property type="entry name" value="CRIB_dom_sf"/>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
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    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
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    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0589">Pheromone response</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="12">
        <location>
            <begin position="86"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="14">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="580"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="265"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="388"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="457"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="499"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="535"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA50946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="869" mass="95362" checksum="60C8C189019B57FB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N861</accession>
    <name>G4N861_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylulose kinase</fullName>
            <ecNumber evidence="7">2.7.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_12860</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17140"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.17" evidence="7"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717281.1">
        <property type="nucleotide sequence ID" value="XM_003717233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N861"/>
    <dbReference type="SMR" id="G4N861"/>
    <dbReference type="FunCoup" id="G4N861">
        <property type="interactions" value="504"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N861"/>
    <dbReference type="GeneID" id="5050228"/>
    <dbReference type="KEGG" id="mgr:MGG_12860"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12860"/>
    <dbReference type="eggNOG" id="KOG2531">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016149_5_0_1"/>
    <dbReference type="InParanoid" id="G4N861"/>
    <dbReference type="OMA" id="NSCALGG"/>
    <dbReference type="OrthoDB" id="1728974at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004856">
        <property type="term" value="F:D-xylulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005998">
        <property type="term" value="P:xylulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07776">
        <property type="entry name" value="ASKHA_NBD_FGGY_SpXK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000118">
        <property type="entry name" value="Xylulose kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042024">
        <property type="entry name" value="D-XK_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF57">
        <property type="entry name" value="XYLULOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="8">
        <location>
            <begin position="134"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="9">
        <location>
            <begin position="301"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA50962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="577" mass="62670" checksum="BEC1D9F3E3FAD479" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8H9</accession>
    <name>G4N8H9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial metal transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_06247</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003717298.1"/>
    </dbReference>
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    <dbReference type="FunCoup" id="G4N8H9">
        <property type="interactions" value="91"/>
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    <dbReference type="STRING" id="242507.G4N8H9"/>
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    <dbReference type="KEGG" id="mgr:MGG_06247"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06247"/>
    <dbReference type="eggNOG" id="KOG1485">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_013430_12_1_1"/>
    <dbReference type="InParanoid" id="G4N8H9"/>
    <dbReference type="OMA" id="DVMIHIN"/>
    <dbReference type="OrthoDB" id="435980at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:inorganic ion homeostasis"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="entry name" value="Cation efflux family protein"/>
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    </dbReference>
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        <property type="entry name" value="Cation efflux family protein, putative"/>
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        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
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    </dbReference>
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        <property type="entry name" value="Cation_efflux_CTD_sf"/>
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    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
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        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF15">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="9">
        <location>
            <begin position="166"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="74"/>
            <end position="111"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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            <end position="148"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="511"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA51027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8L2</accession>
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            <fullName evidence="3">Uncharacterized protein</fullName>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003716525.1">
        <property type="nucleotide sequence ID" value="XM_003716477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8L2"/>
    <dbReference type="GeneID" id="5051812"/>
    <dbReference type="KEGG" id="mgr:MGG_14465"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14465"/>
    <dbReference type="eggNOG" id="ENOG502SBH7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_430237_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8L2"/>
    <dbReference type="OMA" id="RTNTECH"/>
    <dbReference type="OrthoDB" id="4851624at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466701" evidence="2">
        <location>
            <begin position="19"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8N6</accession>
    <name>G4N8N6_PYRO7</name>
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        <recommendedName>
            <fullName evidence="5">TAM domain methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03393</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA50230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003716501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8N6"/>
    <dbReference type="GeneID" id="2676546"/>
    <dbReference type="KEGG" id="mgr:MGG_03393"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03393"/>
    <dbReference type="eggNOG" id="ENOG502R8QF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_1_2_1"/>
    <dbReference type="InParanoid" id="G4N8N6"/>
    <dbReference type="OMA" id="CSAMRKQ"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF31">
        <property type="entry name" value="LAEA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="339"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="352"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="46174" checksum="E567D37CBCAF9BE0" modified="2011-12-14" version="1">MAEIVPDFQDDTDGDSAIDVPFEESLTSVRSSIFAFQQENGRTYHAMSAGKYFLPNDHEEVQRLDLQHYVMIKTLNGRHCLCPKNETATSVLDLGTGTGIWAIEYADAHPEAHVIGVDLSPVQPEFAPPNCTFEIDDLEKEWTWSTKFDFIFARMMTGSFSENRSVVEKVFDQLEPGGYFEAQDMALPLGCDDGTLKTDSDFWKWCNLVMDGMKAFGRPVAAAQEWKKLMEDVGFEDVVETVYKWPTNQWPRDPFYKELGTWSLMNMDAALEPSTMVPLTRALGWSKDEVTVLVAKTRKELRDPRIHAYWPIYVVYGRKPFRPSAPAWSPEPVPIATPTAAPAPAPAPAPAPASSAAPAPAPVETESEAAPPKATAEATASKEQAEATSSKGAEASEKTVEGKDAKEEVGSSSAADAKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8Q5</accession>
    <name>G4N8Q5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717370.1">
        <property type="nucleotide sequence ID" value="XM_003717322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8Q5"/>
    <dbReference type="GeneID" id="2675262"/>
    <dbReference type="KEGG" id="mgr:MGG_10995"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10995"/>
    <dbReference type="HOGENOM" id="CLU_1245598_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8Q5"/>
    <dbReference type="OrthoDB" id="5224023at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465935" evidence="2">
        <location>
            <begin position="21"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="222" mass="23629" checksum="EAA74DFAA924796A" modified="2011-12-14" version="1">MRSILYLVTGALGMVTFAHALPALFFTSTNTLDITGRSVGPFEPGRNSVNGETNYQNHQILQKRVKPHKVSITNNAGASGSRGGGLPSDTVDTWIEAAQIALASISCNQGTITNGPHSGEDSSSSDPKEHITVQPHNGGPKMHVRILLPPPPPRLPVARITRLAIDNNHPPVPSSPHLLGTSSPWLQTTDSSAVWTQAPLDKKPSTAVRRIPRAPEGTGSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAE2</accession>
    <name>G4NAE2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03183</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716806.1">
        <property type="nucleotide sequence ID" value="XM_003716758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAE2"/>
    <dbReference type="SMR" id="G4NAE2"/>
    <dbReference type="GeneID" id="2676556"/>
    <dbReference type="KEGG" id="mgr:MGG_03183"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03183"/>
    <dbReference type="eggNOG" id="ENOG502R6NR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024934_7_0_1"/>
    <dbReference type="InParanoid" id="G4NAE2"/>
    <dbReference type="OMA" id="RNCKTRK"/>
    <dbReference type="OrthoDB" id="5419315at2759"/>
    <dbReference type="PHI-base" id="PHI:5670"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF7">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="478" mass="53406" checksum="CE9DEAE6DE331E76" modified="2011-12-14" version="1">MDSRGSADTSLPERPFHSKRPHRKSRGGCRNCKARKIKCSEDRPQCRTCVLRMEECVYALPAAKKTARSVVAAATSASSKSSSPPSSASSPSSPSEVANTPQPNEDFAVLPVSPQLAPRPADSDYLDMKLLWFYTAKGCESFNSDLSEYGASKQSMLNQTLRFTIPRIALEHRFLMDCMLGLSALQMSSMENEKIPLSRIMLYNSSAMKGYREAIEAAKPRTFNALLTCSLFMCALSSENFRQPNPPPLFILDWIVVWKGISLIYGMIVQHTGSPLKGNSEPSGLAPLFSRPPVNGEEAARYIPGNLLFMVSSLKEGDEEFPYVQAYYSTLKVLGALYMDLEHTYGPILTLRVITFFTFVPPSFVEAARERRPRALVIIAHWLAFSKLATHIWWMRGLADHEVYNISNVVGDEYHQLMQVPLAAVDIEDYVELARLLSNNYTFEPVRRRLADLPPDKLPALFTDDEDGNYLPVTNPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAV5</accession>
    <name>G4NAV5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="19">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">MGG_03132</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="19"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716866.1">
        <property type="nucleotide sequence ID" value="XM_003716818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAV5"/>
    <dbReference type="SMR" id="G4NAV5"/>
    <dbReference type="FunCoup" id="G4NAV5">
        <property type="interactions" value="816"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAV5"/>
    <dbReference type="GeneID" id="2676710"/>
    <dbReference type="KEGG" id="mgr:MGG_03132"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03132"/>
    <dbReference type="eggNOG" id="KOG1131">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011312_1_0_1"/>
    <dbReference type="InParanoid" id="G4NAV5"/>
    <dbReference type="OMA" id="WQTMGIL"/>
    <dbReference type="OrthoDB" id="272481at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045951">
        <property type="term" value="P:positive regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.40:FF:000001">
        <property type="entry name" value="DNA repair helicase (Rad3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.20:FF:000001">
        <property type="entry name" value="DNA repair helicase rad15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000135">
        <property type="entry name" value="DNA repair helicase RAD3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000128">
        <property type="entry name" value="Putative DNA repair helicase RAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000381">
        <property type="entry name" value="TFIIH basal transcription factor complex helicase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.20">
        <property type="entry name" value="Bacterial XPD DNA helicase, FeS cluster domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001945">
        <property type="entry name" value="RAD3/XPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042493">
        <property type="entry name" value="XPD_DNA_FeS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00852">
        <property type="entry name" value="XRODRMPGMNTD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="21" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 23" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="17" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0804">Transcription</keyword>
    <keyword evidence="13" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="22">
        <location>
            <begin position="7"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="21">
        <location>
            <begin position="255"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EHA50547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="795" mass="91067" checksum="28329AF84F313B29" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB40</accession>
    <name>G4NB40_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_11534</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718386.1">
        <property type="nucleotide sequence ID" value="XM_003718338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB40"/>
    <dbReference type="STRING" id="242507.G4NB40"/>
    <dbReference type="GeneID" id="5050690"/>
    <dbReference type="KEGG" id="mgr:MGG_11534"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11534"/>
    <dbReference type="eggNOG" id="KOG2588">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008057_1_0_1"/>
    <dbReference type="InParanoid" id="G4NB40"/>
    <dbReference type="OMA" id="RVKTWDI"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="PHI-base" id="PHI:5033"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032933">
        <property type="term" value="P:SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11399">
        <property type="entry name" value="bHLHzip_scHMS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000116">
        <property type="entry name" value="Putative HLH transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019006">
        <property type="entry name" value="Sre1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09427">
        <property type="entry name" value="DUF2014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="232"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="983"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="296"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1018"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1027" mass="111145" checksum="73211201AD3F13E5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB42</accession>
    <name>G4NB42_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718388.1">
        <property type="nucleotide sequence ID" value="XM_003718340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB42"/>
    <dbReference type="GeneID" id="12984076"/>
    <dbReference type="KEGG" id="mgr:MGG_17403"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17403"/>
    <dbReference type="HOGENOM" id="CLU_2413693_0_0_1"/>
    <dbReference type="InParanoid" id="G4NB42"/>
    <dbReference type="OrthoDB" id="10550970at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="92" mass="10122" checksum="A037B2F57A2F912D" modified="2011-12-14" version="1">MDEGFPGPSMRPASHKERAPINNIWSNVRMLRTMISTELVVLVSIVGTQLMVELPPRSGVCGQIMSDLERHVPGMARSTSNHYTHAVPRIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBM2</accession>
    <name>G4NBM2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_10774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717711.1">
        <property type="nucleotide sequence ID" value="XM_003717663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBM2"/>
    <dbReference type="GeneID" id="2676272"/>
    <dbReference type="KEGG" id="mgr:MGG_10774"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10774"/>
    <dbReference type="HOGENOM" id="CLU_1982019_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBM2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466803" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14065" checksum="1ED6D06D1A6A423F" modified="2011-12-14" version="1">MLLLLLLLLPVPDIRTVARWLSVEMAPRLNFLMPTSLGEPQRHRDPFRGKSLCEVDDAVGSRCTWAEPEAQQPKTHFSVAVTVVVADVHMHFVFNFGCDFRNHAKAEVLSSIEKMADGAHLDGNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCG9</accession>
    <name>G4NCG9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosome biogenesis protein TSR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01087</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717850.1">
        <property type="nucleotide sequence ID" value="XM_003717802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCG9"/>
    <dbReference type="SMR" id="G4NCG9"/>
    <dbReference type="FunCoup" id="G4NCG9">
        <property type="interactions" value="1001"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NCG9"/>
    <dbReference type="GeneID" id="2674231"/>
    <dbReference type="KEGG" id="mgr:MGG_01087"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01087"/>
    <dbReference type="eggNOG" id="KOG1980">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009858_1_0_1"/>
    <dbReference type="InParanoid" id="G4NCG9"/>
    <dbReference type="OMA" id="MNLPRFK"/>
    <dbReference type="OrthoDB" id="119302at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000461">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF1">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22298">
        <property type="entry name" value="Tsr1_G-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="6">
        <location>
            <begin position="85"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="399"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA48266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="810" mass="90426" checksum="B902FD7D53922AD9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2025-06-18" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCP4</accession>
    <name>DCI1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase</fullName>
            <ecNumber evidence="6">5.3.3.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peroxisomal di-isomerase DCI1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DCI1</name>
        <name type="ORF">MGG_00359</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2023" name="Plant Commun." volume="4" first="100561" last="100561">
            <title>MoLrp1-mediated signaling induces nuclear accumulation of MoMsn2 to facilitate fatty acid oxidation for infectious growth of the rice blast fungus.</title>
            <authorList>
                <person name="Zhang T."/>
                <person name="Wang X."/>
                <person name="Li X."/>
                <person name="Li Y.N."/>
                <person name="Li Y."/>
                <person name="Wu S."/>
                <person name="Xu L."/>
                <person name="Zhou R."/>
                <person name="Yang J."/>
                <person name="Li G."/>
                <person name="Liu X."/>
                <person name="Zheng X."/>
                <person name="Zhang Z."/>
                <person name="Zhang H."/>
            </authorList>
            <dbReference type="PubMed" id="36774535"/>
            <dbReference type="DOI" id="10.1016/j.xplc.2023.100561"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>INDUCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <scope>SUBCELLULAR LOCATION</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Peroxisomal di-isomerase that is involved in fatty acid metabolism enzyme by converting 3,5-dienoyl-CoAs to the corresponding 2,4-dienoyl-CoAs (PubMed:36774535). Involved in fatty acid beta-oxidation, which is important for lipid droplets degradation and infectious growth (PubMed:36774535).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:45240"/>
            <dbReference type="ChEBI" id="CHEBI:85110"/>
            <dbReference type="ChEBI" id="CHEBI:85111"/>
            <dbReference type="EC" id="5.3.3.21"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:45241"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
        <text evidence="3">Mainly distributed in the cytosol in vegetative hyphae and conidia but localizes in peroxisomes in appressoria and infectious hyphae.</text>
    </comment>
    <comment type="induction">
        <text evidence="3">Expression is regulated by the transcription factor MSN2.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="3">Leads to reduced virulence with smaller lesions with restricted growth of infectious hyphae and fewer blast lesions and green islands on barley leaves (PubMed:36774535). Does not affect vegetative growth, conidium production, and appressorium formation but shows defects in long-chain (oleate and olive oil) fatty acids oxidation (PubMed:36774535). Results in fewer peroxisomes, more lipid droplets, and higher levels of phosphatidylglycerol, phosphatidylinositol, diacylglycerol, triacylglycerol and free fatty acids (PubMed:36774535).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.21" evidence="6"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718722.1">
        <property type="nucleotide sequence ID" value="XM_003718674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCP4"/>
    <dbReference type="SMR" id="G4NCP4"/>
    <dbReference type="FunCoup" id="G4NCP4">
        <property type="interactions" value="207"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NCP4"/>
    <dbReference type="EnsemblFungi" id="MGG_00359T0">
        <property type="protein sequence ID" value="MGG_00359T0"/>
        <property type="gene ID" value="MGG_00359"/>
    </dbReference>
    <dbReference type="GeneID" id="2675176"/>
    <dbReference type="KEGG" id="mgr:MGG_00359"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00359"/>
    <dbReference type="eggNOG" id="KOG0016">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_6_2_1"/>
    <dbReference type="InParanoid" id="G4NCP4"/>
    <dbReference type="OMA" id="FQAIMDF"/>
    <dbReference type="OrthoDB" id="448450at2759"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051750">
        <property type="term" value="F:delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000048">
        <property type="entry name" value="3,2-trans-enoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0576">Peroxisome</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <feature type="chain" id="PRO_0000462290" description="Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Peroxisome targeting signal (PTS1)" evidence="2">
        <location>
            <begin position="278"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q05871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="Q08558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="36774535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="4">
        <source>
            <dbReference type="PubMed" id="36774535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <evidence type="ECO:0000305" key="6">
        <source>
            <dbReference type="PubMed" id="36774535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA49138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="280" mass="30644" checksum="17AD87D574EAB7DC" modified="2011-12-14" version="1">MSGVTTVEYRGRVAVITICNERKLNALDLHGYYELSERMREVATHDEVYVTLLTAKGRFFSAGADVSTIRDPPTTGEDDSGIADGGRRQWLQSFVAFNLNITQAFYSHPKILVVGLNGPVVGLSAALVSFADFIYATPSTFLLTPFSSLGLVAEGGASRALVQRLGVSKANEALLMSRRVPADELLQTGFVNKVFTELKGAKDDDVRFKELVLAEIDDKLGDHLVGDSLIGIKELIRRPEIDVLEGQNAREVFAGLGRFMSGVPQREFLKLASGEKRHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCX8</accession>
    <name>G4NCX8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718752.1">
        <property type="nucleotide sequence ID" value="XM_003718704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCX8"/>
    <dbReference type="STRING" id="242507.G4NCX8"/>
    <dbReference type="GeneID" id="2675138"/>
    <dbReference type="KEGG" id="mgr:MGG_00333"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00333"/>
    <dbReference type="eggNOG" id="ENOG502S22Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035244_1_1_1"/>
    <dbReference type="InParanoid" id="G4NCX8"/>
    <dbReference type="OMA" id="AYPKIAQ"/>
    <dbReference type="OrthoDB" id="10039566at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="343" mass="37598" checksum="0D12CAECE372A42C" modified="2011-12-14" version="1">MSDKDIAREGIVAHENTSGKPRKRGCIGHCGRFWWVYLIALIVIIVIVVPVVILVAVPKIAQDKINAAELDVRDIKALDTQTQNFTMTIDSGIRTDGKVHAKVAPFEGVMYLEDWAPQRPFAKIQFPETSSAASQDVSVKQFVNIEDMEAFTVFNTWLLLNNTLRVTIKGDTSVRVDGIARDYPVVFKKTTTMPGLNLFKGTSVSDPKIITGNHTEDNGANFQGTVTIPNQSHVTFEVGNATFFNYLGDQDVGEVYINNMTIRPGDNVFPMTAKVSNEAVVAAMTKRPACETGKLTFGLRGKKVVNHGQPLPYFADSLASANQTVEIDISQALGFKIPCSQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND64</accession>
    <name>G4ND64_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phospholipase D1</fullName>
            <ecNumber evidence="3">3.1.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Choline phosphatase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Phosphatidylcholine-hydrolyzing phospholipase D1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_00960</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
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            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phospholipase D family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003717942.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_00960"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_000690_3_2_1"/>
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    <dbReference type="OrthoDB" id="14911at2759"/>
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        <property type="component" value="Chromosome 5"/>
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        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="PH_PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_1"/>
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        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_2"/>
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        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF76">
        <property type="entry name" value="PHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
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            <begin position="760"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="12">
        <location>
            <begin position="1065"/>
            <end position="1092"/>
        </location>
    </feature>
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            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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            <end position="109"/>
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    <feature type="region of interest" description="Disordered" evidence="11">
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    <feature type="region of interest" description="Disordered" evidence="11">
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            <end position="437"/>
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    <feature type="region of interest" description="Disordered" evidence="11">
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    <feature type="region of interest" description="Disordered" evidence="11">
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    <feature type="region of interest" description="Disordered" evidence="11">
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            <end position="1464"/>
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    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1477"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1542"/>
            <end position="1597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1217"/>
            <end position="1229"/>
        </location>
    </feature>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
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        <source>
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        <source>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        <source>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="EMBL" id="EHA48406.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1646" mass="186426" checksum="9DF97C0A165B2754" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDD3</accession>
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        <submittedName>
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        </submittedName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003717958.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NDD3"/>
    <dbReference type="GeneID" id="2674093"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_00944"/>
    <dbReference type="eggNOG" id="ENOG502S1UN">
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    <dbReference type="InParanoid" id="G4NDD3"/>
    <dbReference type="OMA" id="ATHPNMW"/>
    <dbReference type="OrthoDB" id="14339at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
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    <dbReference type="PANTHER" id="PTHR37332:SF1">
        <property type="entry name" value="ELMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="186"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA48422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="479" mass="52140" checksum="F8F7585CFF039A2D" modified="2011-12-14" version="1">MRRGSGSLSTFPQIQHAYSNPPPATSLAINDGAQQQQQQQNTQTHTRSRSNSITSRLLRPSTSSGDQQQQKVTLYPNPPPETPRLGGVLTKERRPSFGRKSSFSRLRRSSSASNVAAAAAKEPPGRQGKLRVTTDRSAPPLPDISRSRYSRLDSAQDSSFYLQSPPLSADSFSKMLSRTTTNNNGGQMVPPPAPTSGQTDSHSMVYQHIQETASKRISTLDYLRKAHEGRVYWFNTLLFDKPDLARMPYFDSRKLARRATNYLLLGLSLPAVVDLNSSTPLEFLRSLNILLGEFETFQTLHSESGTAASSLSRARIPNMFRRGAQSAKTRRTSGANDLGIAGLDQSESNGGPLTGNPLDGGSSAGGDAPALSFAASDTDLLPGEEYTHLLTPSLPFDPDFFETFATLCDVLIDCYRRLLTLLSSPKDCNAQIAELFTKADARVRKIIIQGAVKEFEDTSRAGVKNEVANVGKVVLGSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDR0</accession>
    <name>G4NDR0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">26S proteasome non-ATPase regulatory subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_00884</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S3 family.</text>
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        <property type="protein sequence ID" value="EHA48498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="KEGG" id="mgr:MGG_00884"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00884"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:regulation of protein catabolic process"/>
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        <property type="entry name" value="PCI_dom"/>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rpn3_C"/>
        <property type="match status" value="1"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
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    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
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            <begin position="542"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007912"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA48498.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="11">Ras guanine nucleotide exchange factor A</fullName>
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        <name evidence="9" type="ORF">MGG_00199</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49332.1"/>
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        <property type="nucleotide sequence ID" value="XM_003718868.1"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0007265">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
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        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ras-like_GEF"/>
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        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
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    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
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        <property type="entry name" value="RASGEF_cat_dom"/>
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    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
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    </dbReference>
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        <property type="entry name" value="BUD SITE SELECTION PROTEIN 5"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="8">
        <location>
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            <end position="916"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="7">
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            <end position="1228"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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            <end position="114"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="5">
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    <feature type="region of interest" description="Disordered" evidence="5">
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        <location>
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    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
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    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="717"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
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            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1240"/>
            <end position="1256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1295" mass="141801" checksum="61EB70CD60EAC6DE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE79</accession>
    <name>G4NE79_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MGG_00139</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 22">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the BRE1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718992.1">
        <property type="nucleotide sequence ID" value="XM_003718944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE79"/>
    <dbReference type="SMR" id="G4NE79"/>
    <dbReference type="FunCoup" id="G4NE79">
        <property type="interactions" value="882"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NE79"/>
    <dbReference type="GeneID" id="2675200"/>
    <dbReference type="KEGG" id="mgr:MGG_00139"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00139"/>
    <dbReference type="eggNOG" id="KOG0978">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019713_2_0_1"/>
    <dbReference type="InParanoid" id="G4NE79"/>
    <dbReference type="OMA" id="YRQMQEY"/>
    <dbReference type="OrthoDB" id="654191at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="PHI-base" id="PHI:6928"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058643">
        <property type="entry name" value="BRE1-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08647">
        <property type="entry name" value="BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26095">
        <property type="entry name" value="CC_Bre1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 15 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="671"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="19">
        <location>
            <begin position="704"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="281"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="564"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EHA49408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="723" mass="81925" checksum="107C8C6FFDC7F815" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEH1</accession>
    <name>G4NEH1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719032.1">
        <property type="nucleotide sequence ID" value="XM_003718984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEH1"/>
    <dbReference type="STRING" id="242507.G4NEH1"/>
    <dbReference type="GeneID" id="12985130"/>
    <dbReference type="KEGG" id="mgr:MGG_17536"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17536"/>
    <dbReference type="eggNOG" id="ENOG502T6SS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1299937_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEH1"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466180" evidence="1">
        <location>
            <begin position="23"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="212" mass="22887" checksum="3ED41DD2479482E1" modified="2011-12-14" version="1">MFRSSFISGSLLLLSLLGNVQAGVVQPPAVKSAIIPIELDLDPQLIIKAGGLTPKLAKTVTNQQIVTAALDTDIIQEIKKKHPRKPTYVRILLPPPPPRLPVARITRLAIDNNHPPVPSSPHLLGTSSPWLQTTDSSAVWTQAPLDEEPSTAVRRILPQANAIWSLACSATCQGRRTRLVMLIPPQMGVVDVACRGRGIREGAGQAKEGFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEH3</accession>
    <name>G4NEH3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone transcription regulator 3 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_00105</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HIR3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719034.1">
        <property type="nucleotide sequence ID" value="XM_003718986.1"/>
    </dbReference>
    <dbReference type="FunCoup" id="G4NEH3">
        <property type="interactions" value="121"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NEH3"/>
    <dbReference type="GeneID" id="2674848"/>
    <dbReference type="KEGG" id="mgr:MGG_00105"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00105"/>
    <dbReference type="eggNOG" id="ENOG502QQX4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001419_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEH3"/>
    <dbReference type="OMA" id="WETWYRL"/>
    <dbReference type="OrthoDB" id="77564at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033053">
        <property type="entry name" value="Hir3/CABIN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502:SF7">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="346"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1740"/>
            <end position="2011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1769"/>
            <end position="1778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1793"/>
            <end position="1806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1840"/>
            <end position="1857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1865"/>
            <end position="1875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1887"/>
            <end position="1903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1939"/>
            <end position="2011"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA49450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="2011" mass="224928" checksum="B8F6CF758D0DEC60" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEL7</accession>
    <name>G4NEL7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_00765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718231.1">
        <property type="nucleotide sequence ID" value="XM_003718183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEL7"/>
    <dbReference type="STRING" id="242507.G4NEL7"/>
    <dbReference type="GeneID" id="2674326"/>
    <dbReference type="KEGG" id="mgr:MGG_00765"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00765"/>
    <dbReference type="eggNOG" id="ENOG502SRN0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103863_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEL7"/>
    <dbReference type="OMA" id="KCTEWTM"/>
    <dbReference type="OrthoDB" id="4135672at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046670">
        <property type="entry name" value="DUF6540"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20174">
        <property type="entry name" value="DUF6540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="155" mass="17012" checksum="1ED95F9B59F5AB95" modified="2011-12-14" version="1">MADPDLPQPRYHHVVFVQTNADDGSGVKFHVVGDITSLGGMTYESTEFGNPLDDPAFHGSDLLGFTIGDGFRRRWDEVLGGLPTPPKQKEYNVATGRTELVKTWNPLAFYAPGEERQPPWKCTEWTMDHAIPALWKNGLIVDATTKAVAGARGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEQ8</accession>
    <name>G4NEQ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-galactose dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_00075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
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                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <source>
            <dbReference type="Pfam" id="PF00248"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA49481.1"/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="413" mass="43567" checksum="DB4740E16DD73A45" modified="2011-12-14" version="1">MGSVTMSTSTMEETATPAKSVNGSGHRPPLSTILPPMILGSATFNSQYVRDPSAMPARPIVSRAFDLGIRAFDTSPYYGPAELLLGDALAAAARPRDSYLLISKAGRVGPTTFDYSPAAVTASIHRSLERLRTPYLDLAYLHDVEFVTTADVLAGLGALRALQSQGLIRYVGISGYPVARLLELAEAITATTGSPVDAILSYAHFSVQNTILAAPETLARFRRAGVDVVLNASILAMGLLTPGISAGPQESWHPAPEGLRAACVALRKECAARGGKRLEEIAIEYALREWGRLAIDAGVAVGRGVGQQTVGGTVIGVTSVRELEETMAAWASACRDLGLVEDGHKAGVTNGNGHVDAVGGAKGGPEDVVAFVRDVMWPILGEWKDFSWDSPHKGWFGEHGNVVGSKDPMSNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
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        <name evidence="4" type="ORF">MGG_00731</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Young S.K."/>
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                <person name="Gargeya S."/>
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                <person name="Haas B."/>
                <person name="Abouelleil A."/>
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                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
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                <person name="Dunbar C."/>
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                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA48687.1"/>
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        <property type="entry name" value="Far11/STRP"/>
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        <property type="entry name" value="Far11/STRP_N"/>
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        <property type="entry name" value="AT25231P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239">
        <property type="entry name" value="PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="N1221"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF3402"/>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <end position="417"/>
        </location>
    </feature>
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        <location>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA48687.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="1022" mass="113859" checksum="486DF74B7D2D99E5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the G-alpha family. G(q) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719617.1">
        <property type="nucleotide sequence ID" value="XM_003719569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF72"/>
    <dbReference type="SMR" id="G4NF72"/>
    <dbReference type="FunCoup" id="G4NF72">
        <property type="interactions" value="477"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NF72"/>
    <dbReference type="GeneID" id="2677128"/>
    <dbReference type="KEGG" id="mgr:MGG_04204"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04204"/>
    <dbReference type="eggNOG" id="KOG0082">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014184_6_0_1"/>
    <dbReference type="InParanoid" id="G4NF72"/>
    <dbReference type="OMA" id="ANSHWFK"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090726">
        <property type="term" value="C:cortical dynamic polarity patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180040">
        <property type="term" value="P:negative regulation of pheromone response MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000009">
        <property type="entry name" value="Guanine nucleotide-binding protein G(O) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000051">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF242">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="176"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="201"/>
            <end position="205"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="270"/>
            <end position="273"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA47250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="356" mass="41318" checksum="F2B539A114418C19" modified="2011-12-14" version="1">MCFGSRNVHDEAGAARSRELDKAIRADEKRLQKEVKLLLLGAGESGKSTVLKQMKLIYAQGFSKNEKIEWKPVVFQNIVQSFRLIHDAMQELDIEFENKENERNITLIMEEQELGAHDALPIEFLDPIKALWVDAGVKKAIAKGNEFALHDNLDYFCDDLDRIWDKSYVPTDQDLLRSRLRTTGITETVFDLGQLTYRMFDVGGQRSERKKWIHCFENVNCLLFLVAISGYDQCLVEDKDGNQMNEALMLWESIANSHWFTKSALILFLNKMDLFKEKITKSPITEYGFTDYHGPSDDWKQTSKYFMDKFRALNRNPEKEIYGHFTNATDTNLLKITMTSVQDMIIQRNLKQLIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFZ0</accession>
    <name>G4NFZ0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_17588</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719314.1">
        <property type="nucleotide sequence ID" value="XM_003719266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFZ0"/>
    <dbReference type="GeneID" id="12985761"/>
    <dbReference type="KEGG" id="mgr:MGG_17588"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17588"/>
    <dbReference type="eggNOG" id="ENOG502SZCW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019059_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFZ0"/>
    <dbReference type="OMA" id="HPIEECQ"/>
    <dbReference type="OrthoDB" id="5361322at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032567">
        <property type="entry name" value="RTL1-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503">
        <property type="entry name" value="LDOC1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503:SF22">
        <property type="entry name" value="TRANSPOSON TY3-I GAG POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="341"/>
            <end position="357"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
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        <location>
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            <end position="94"/>
        </location>
    </feature>
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        <location>
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            <end position="303"/>
        </location>
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        <location>
            <begin position="319"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="358"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="511"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="524" mass="60035" checksum="DD204DDE6B90704C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGF9</accession>
    <name>G4NGF9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_04325</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    <dbReference type="STRING" id="242507.G4NGF9"/>
    <dbReference type="GeneID" id="2677377"/>
    <dbReference type="KEGG" id="mgr:MGG_04325"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04325"/>
    <dbReference type="eggNOG" id="KOG4157">
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    <dbReference type="OMA" id="MTSIGCF"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
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        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466506" description="WSC domain-containing protein" evidence="7">
        <location>
            <begin position="23"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
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        <location>
            <begin position="48"/>
            <end position="139"/>
        </location>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="EHA47116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="281" mass="29598" checksum="B14653B4C6FE7614" modified="2011-12-14" version="1">MKSFIIASGAALLCAVSGAAVGTPVLVPRATPSVWAVQRPSERPVANDPRVQGCFSSAGDLTFVQTVEYNSRDSCPKAICNTKLGKDVGGTIRGNECWCGDKYPPKSSLVDDKDCNAACTGYGQEACGGDKVWTIYNTGKQAYGVDYMPDETKNNTQTDAPKPVVSSAAPSSTPSAPPQSSGSNTAGIAAGVVVGVVALAAIAGGAWFFYRKRRNQALEEEHRRNAAVNAFIHGNKPPSSSGGVSLTDSRMDPQMAQRRMSDGSIADNQDYSRRILRVTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGQ1</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719778.1">
        <property type="nucleotide sequence ID" value="XM_003719730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGQ1"/>
    <dbReference type="GeneID" id="12986209"/>
    <dbReference type="KEGG" id="mgr:MGG_14918"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14918"/>
    <dbReference type="HOGENOM" id="CLU_2923109_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGQ1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="61" mass="6067" checksum="5C374F81420FDBED" modified="2011-12-14" version="1">MARDEAAASLSDMSGANVSQGRSAAGAGADENSTRCAHSAMLMPENIGRNAHGLFSADSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGY9</accession>
    <name>G4NGY9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719866.1">
        <property type="nucleotide sequence ID" value="XM_003719818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGY9"/>
    <dbReference type="STRING" id="242507.G4NGY9"/>
    <dbReference type="GeneID" id="12986249"/>
    <dbReference type="KEGG" id="mgr:MGG_17713"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17713"/>
    <dbReference type="eggNOG" id="ENOG502RMFT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_517819_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGY9"/>
    <dbReference type="OMA" id="TETIRHQ"/>
    <dbReference type="OrthoDB" id="5227090at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="578"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="636" mass="65057" checksum="DF55504A3F97C3AB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGZ8</accession>
    <name>G4NGZ8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Ubiquitin-related modifier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">URM1</name>
        <name evidence="8" type="ORF">MGG_03978</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the URM1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA47508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719875.1">
        <property type="nucleotide sequence ID" value="XM_003719827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGZ8"/>
    <dbReference type="SMR" id="G4NGZ8"/>
    <dbReference type="FunCoup" id="G4NGZ8">
        <property type="interactions" value="884"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGZ8"/>
    <dbReference type="GeneID" id="2677433"/>
    <dbReference type="KEGG" id="mgr:MGG_03978"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03978"/>
    <dbReference type="eggNOG" id="KOG4146">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148208_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGZ8"/>
    <dbReference type="OMA" id="DYELQPN"/>
    <dbReference type="OrthoDB" id="10248987at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01764">
        <property type="entry name" value="Ubl_Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03048">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015221">
        <property type="entry name" value="Urm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14986">
        <property type="entry name" value="RURM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09138">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="modified residue" description="1-thioglycine" evidence="5">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)" evidence="5">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="129" mass="14065" checksum="16F4889AB94A5F5F" modified="2011-12-14" version="1">MHQVETVSAAPASLGSSDQDNATQQAPSLNIVVEFSGGLEMLFADRRRLQLTVPKSDDRGKPLTIAALIDHLCQHEMNDGRKDLFVLDGHLRPGILVLINDADWELEGEEAYEVQSGDNVLFVSTLHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHH5</accession>
    <name>G4NHH5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720052.1">
        <property type="nucleotide sequence ID" value="XM_003720004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHH5"/>
    <dbReference type="SMR" id="G4NHH5"/>
    <dbReference type="GeneID" id="12987131"/>
    <dbReference type="KEGG" id="mgr:MGG_17742"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17742"/>
    <dbReference type="HOGENOM" id="CLU_3143436_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHH5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="49" mass="5301" checksum="6C34D6EA97370B8C" modified="2011-12-14" version="1">MNQNGTIVIIILCMIAIIGLTIYLARTVMSKFITNTLEAKDRATDSSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHK6</accession>
    <name>G4NHK6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03811</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720083.1">
        <property type="nucleotide sequence ID" value="XM_003720035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHK6"/>
    <dbReference type="SMR" id="G4NHK6"/>
    <dbReference type="GeneID" id="2677222"/>
    <dbReference type="KEGG" id="mgr:MGG_03811"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03811"/>
    <dbReference type="eggNOG" id="KOG0159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025001_1_0_1"/>
    <dbReference type="InParanoid" id="G4NHK6"/>
    <dbReference type="OMA" id="AGPRMCY"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466344" description="Cytochrome P450" evidence="8">
        <location>
            <begin position="24"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="512"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="62671" checksum="44175AC4480DE296" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHQ2</accession>
    <name>G4NHQ2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GPI transamidase component GPI16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03759</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720129.1">
        <property type="nucleotide sequence ID" value="XM_003720081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHQ2"/>
    <dbReference type="SMR" id="G4NHQ2"/>
    <dbReference type="FunCoup" id="G4NHQ2">
        <property type="interactions" value="554"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NHQ2"/>
    <dbReference type="GeneID" id="2677421"/>
    <dbReference type="KEGG" id="mgr:MGG_03759"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03759"/>
    <dbReference type="eggNOG" id="KOG2407">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021459_2_1_1"/>
    <dbReference type="InParanoid" id="G4NHQ2"/>
    <dbReference type="OMA" id="NHGHYIG"/>
    <dbReference type="OrthoDB" id="331263at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007245">
        <property type="entry name" value="PIG-T"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959:SF11">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04113">
        <property type="entry name" value="Gpi16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466350" evidence="3">
        <location>
            <begin position="26"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="563"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="645" mass="70922" checksum="C1AFB752C90EEF75" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHU7</accession>
    <name>G4NHU7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720174.1">
        <property type="nucleotide sequence ID" value="XM_003720126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHU7"/>
    <dbReference type="GeneID" id="12987208"/>
    <dbReference type="KEGG" id="mgr:MGG_17780"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17780"/>
    <dbReference type="HOGENOM" id="CLU_1970985_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHU7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466662" evidence="2">
        <location>
            <begin position="18"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="127" mass="13983" checksum="6132D286E9A88A0F" modified="2011-12-14" version="1">MAILWILARMRIALLRARWRFRIDWIRPIILTRTSLPETPLNRSWTAASPTSPVTAGDKAVLLVRVPTGAGRSIGSETTGSGIPTRGVSSHKPRAVFAVVNQDSGKRQGAQARDEGELEWDGEVHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI79</accession>
    <name>G4NI79_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycoside hydrolase 131 catalytic N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720306.1">
        <property type="nucleotide sequence ID" value="XM_003720258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI79"/>
    <dbReference type="SMR" id="G4NI79"/>
    <dbReference type="STRING" id="242507.G4NI79"/>
    <dbReference type="GeneID" id="2680404"/>
    <dbReference type="KEGG" id="mgr:MGG_09321"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09321"/>
    <dbReference type="eggNOG" id="ENOG502SKJS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063723_1_1_1"/>
    <dbReference type="InParanoid" id="G4NI79"/>
    <dbReference type="OMA" id="HGENQTW"/>
    <dbReference type="OrthoDB" id="5283326at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041524">
        <property type="entry name" value="GH131_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612">
        <property type="entry name" value="GH131_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34612:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE 131 CATALYTIC N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18271">
        <property type="entry name" value="GH131_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466587" description="Glycoside hydrolase 131 catalytic N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 131 catalytic N-terminal" evidence="2">
        <location>
            <begin position="27"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="364" mass="38316" checksum="B0804B43CFDF0F56" modified="2011-12-14" version="1">MRSFTVASAIFGGLLATSPVYGQQCKLQFDGRVPANFKPANFDTANNIFNPSNVLGKGLKFSDVIELPTLAQQSIFDVAGKTKAVEVTINDKSIFVPNPDTVQNGFRRTELLIASNNGTDDATKGVKTLHFSIAKDLKKPLNLTHEYQLVFLEDNKFSTNQIVVKTGTIDGQANTNPDTLNVFGNVASSPPKLLFSTPFGADGFHNFAMTLDFTKNTTQVFFSKGNEPLKAVSKAEPNDVSGGGQFHFGCLKKGVGKVKDVVREGIQEPNINEGVIYGGIFMEDSANGCISLSAAAGAKAGAVGGAVAGAGAGGAVAKAGAKVAGAAVKKVSQPPRLPKLPTRRALSSLDVLEMRLSSLAPRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI95</accession>
    <name>G4NI95_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T1</fullName>
            <ecNumber evidence="2">4.6.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_10720</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[RNA] containing guanosine + H2O = an [RNA fragment]-3'-guanosine-3'-phosphate + a 5'-hydroxy-ribonucleotide-3'-[RNA fragment].</text>
            <dbReference type="EC" id="4.6.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.24" evidence="2"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720322.1">
        <property type="nucleotide sequence ID" value="XM_003720274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI95"/>
    <dbReference type="SMR" id="G4NI95"/>
    <dbReference type="GeneID" id="2682895"/>
    <dbReference type="KEGG" id="mgr:MGG_10720"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10720"/>
    <dbReference type="eggNOG" id="ENOG502SA4T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111658_0_1_1"/>
    <dbReference type="InParanoid" id="G4NI95"/>
    <dbReference type="OMA" id="YEFPLRT"/>
    <dbReference type="OrthoDB" id="5425539at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046589">
        <property type="term" value="F:ribonuclease T1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00606">
        <property type="entry name" value="fungal_RNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.30">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="N1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42104">
        <property type="entry name" value="EXTRACELLULAR GUANYL-SPECIFIC RIBONUCLEASE RNTA (AFU_ORTHOLOGUE AFUA_4G03230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42104:SF1">
        <property type="entry name" value="EXTRACELLULAR GUANYL-SPECIFIC RIBONUCLEASE RNTA (AFU_ORTHOLOGUE AFUA_4G03230)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="Microbial ribonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466373" description="ribonuclease T1" evidence="10">
        <location>
            <begin position="19"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="180" mass="18517" checksum="CE83967E87FCE68F" modified="2011-12-14" version="1">MIGLKSTLILALAAFSAAASIDSAVISRRQASGVTCGNNNYSSNQVQAAVDRGCSLFASGSTVGSNNYPHRFNNREQLPFPIDGPYQEFPILNNKVYTGGSPGADRVAFTTKNDGTCTFAGAMTHTGASGNNFVSCRGSTSVSDAPTDKPEKTEKQNNAASSLSAGGVAMPVIAAVLVAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJ54</accession>
    <name>G4NJ54_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD repeat-containing protein 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_02743</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721013.1">
        <property type="nucleotide sequence ID" value="XM_003720965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJ54"/>
    <dbReference type="STRING" id="242507.G4NJ54"/>
    <dbReference type="GeneID" id="2682725"/>
    <dbReference type="KEGG" id="mgr:MGG_02743"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02743"/>
    <dbReference type="eggNOG" id="KOG0266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014280_1_1_1"/>
    <dbReference type="InParanoid" id="G4NJ54"/>
    <dbReference type="OMA" id="FGQWTIT"/>
    <dbReference type="OrthoDB" id="63070at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000557">
        <property type="entry name" value="WD repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051859">
        <property type="entry name" value="DCAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19847">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19847:SF7">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="358"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="405"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="609"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="37"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="625"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA46270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="641" mass="72144" checksum="D2D2C45D151F6D81" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJ63</accession>
    <name>G4NJ63_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBX domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_02734</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Directly interacts with VCP. Interacts with UBQLN1. Forms a complex with VCP and UBQLN1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EHA46279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003720974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJ63"/>
    <dbReference type="SMR" id="G4NJ63"/>
    <dbReference type="STRING" id="242507.G4NJ63"/>
    <dbReference type="GeneID" id="2682716"/>
    <dbReference type="KEGG" id="mgr:MGG_02734"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02734"/>
    <dbReference type="eggNOG" id="KOG2689">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035996_1_0_1"/>
    <dbReference type="InParanoid" id="G4NJ63"/>
    <dbReference type="OMA" id="FEPNNTS"/>
    <dbReference type="OrthoDB" id="2445133at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006986">
        <property type="term" value="P:response to unfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46424">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46424:SF1">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23187">
        <property type="entry name" value="UBX7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0834">Unfolded protein response</keyword>
    <feature type="domain" description="UBX" evidence="7">
        <location>
            <begin position="286"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="144"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="245"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="439"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="443"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA46279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="497" mass="53612" checksum="FFAF844A00A4C573" modified="2011-12-14" version="1">MFFDGTLQEGIAAAVQQAKMVVSFVTDGGEESTKWEEEYLVDDSIKTVLSTQAVVLRLQAGSEEAKYLAAIFPLPKTPTLVLIRNGELKEYIASGVSKDDFMARLQKALGVAQPAPAAPAAVANPDESYPAQYAAGHRSTAGGLDSVIQSGSSTSNLAQANTPIPTSHVASGNRAAETQPQSTGAAASKQPDKGKGRAQPAAEDPTPGKAQVEVQKAAEIIKKRKKEANEDRRRILEKIEYDRAERKAREEERRAERRALREGTPVDTGAAAPATVAIPKTQASRTVSEICALQVRDFDGSTIRTRLPSSGTLRKDVREWVDANRSPNGSGPYLFKLVLTPLPNRTIDETEEDKTLLDLELAPSATLILVPVPRFTSAYGGGGGYRRGHGGIVDRINALFVAVMSIFNGFFGMFGRLLTGPPQITQGDAGIEMDELDQNQAQPPQGSSTGRRSPPGSARNRSDNSRVTGFRNPDDDRRDQQLYNGNSLNFEPRPDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJS6</accession>
    <name>G4NJS6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10331</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720486.1">
        <property type="nucleotide sequence ID" value="XM_003720438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJS6"/>
    <dbReference type="GeneID" id="2681906"/>
    <dbReference type="KEGG" id="mgr:MGG_10331"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10331"/>
    <dbReference type="HOGENOM" id="CLU_1337741_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJS6"/>
    <dbReference type="OrthoDB" id="10506818at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="205" mass="21768" checksum="CB8C848D74F8FA65" modified="2011-12-14" version="1">MTMINPMVFAMDSCGTPTDLPKPTFTYILLDARASIIQRVMLADNNTPPVTRTAILPATTATPFSGPSTAAPPPPADPATGPENSEEGPNLVTAIALPVIAAMLLGVIFVLLRQLRKGKKREDLGAEDRALGKAELSSDGVLQVEPQELSADPPEPKGLEVYETPVEVKADMEFPAEIDSAARKEWAAEEQKSLGLGPKGTRVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NK74</accession>
    <name>G4NK74_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720540.1">
        <property type="nucleotide sequence ID" value="XM_003720492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NK74"/>
    <dbReference type="STRING" id="242507.G4NK74"/>
    <dbReference type="GeneID" id="12984717"/>
    <dbReference type="KEGG" id="mgr:MGG_17861"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17861"/>
    <dbReference type="eggNOG" id="ENOG502S9BI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041809_0_0_1"/>
    <dbReference type="InParanoid" id="G4NK74"/>
    <dbReference type="OMA" id="IAVWGRA"/>
    <dbReference type="OrthoDB" id="66095at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA45797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="368" mass="41091" checksum="C6B3D65C1B9EF15F" modified="2011-12-14" version="1">MDNRPQFPLPILRHPFPARGPPPVIPTDDTDATPEASQPTANSTDDPVTESDDMGSSTSRPAHFQPSALDVLVTKAMLAKGVKLPIEVVDLVVDFAEYWPHTRTHVERPSRPNRFGTRPDENNFLLRTPPVGFLGVPHSDPERYTREPVKMLRLSDEHPVEQFQKWIGSPVPLVQHPCRKVVFTIKSRDQGWGGDSRDHGTYHGSWTWFEAGLERVDASGDCGDHCPDTTDQPAQDQTQAQGSGSSSRPRPEISLCALRSIRPEVNCDGERTHFDFPLNPADDKVQCNMTAHNEYITHVVEWRATDNIDPKSAEADELEKMGRGRASGTGEFVRNLKLGDTVTLWAKTRFQGWANNVESATVDVYWAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLG4</accession>
    <name>G4NLG4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721508.1">
        <property type="nucleotide sequence ID" value="XM_003721460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLG4"/>
    <dbReference type="GeneID" id="2680659"/>
    <dbReference type="KEGG" id="mgr:MGG_09581"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09581"/>
    <dbReference type="HOGENOM" id="CLU_1896648_0_0_1"/>
    <dbReference type="InParanoid" id="G4NLG4"/>
    <dbReference type="OMA" id="FGRRCCG"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="134" mass="14709" checksum="5CFCED1A6B5FFD41" modified="2011-12-14" version="1">MVAKVSTSDILRRSSTTSSSNPHCFLDRIIGGKATRGGSWRAETRGRSRLLLHKKLLRIRHRFRPLHGHPALRKGFALSLELFLFGRRCCGKSTPPPSSGSQVACITGYSQQHGVVALQGPLGFKHFSGELCVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLQ6</accession>
    <name>G4NLQ6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_02879</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720852.1">
        <property type="nucleotide sequence ID" value="XM_003720804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLQ6"/>
    <dbReference type="SMR" id="G4NLQ6"/>
    <dbReference type="STRING" id="242507.G4NLQ6"/>
    <dbReference type="GeneID" id="2682432"/>
    <dbReference type="KEGG" id="mgr:MGG_02879"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02879"/>
    <dbReference type="eggNOG" id="ENOG502SHZK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014662_0_0_1"/>
    <dbReference type="InParanoid" id="G4NLQ6"/>
    <dbReference type="OMA" id="HVFAQPD"/>
    <dbReference type="OrthoDB" id="189997at2759"/>
    <dbReference type="PHI-base" id="PHI:5597"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="99"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="518"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="649"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="697"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="708"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA46109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="814" mass="89132" checksum="7D9E284E20790898" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLV2</accession>
    <name>G4NLV2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_02839</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720898.1">
        <property type="nucleotide sequence ID" value="XM_003720850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLV2"/>
    <dbReference type="GeneID" id="2682392"/>
    <dbReference type="KEGG" id="mgr:MGG_02839"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02839"/>
    <dbReference type="eggNOG" id="KOG1812">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025203_1_0_1"/>
    <dbReference type="InParanoid" id="G4NLV2"/>
    <dbReference type="OMA" id="GEFIPPR"/>
    <dbReference type="OrthoDB" id="9977870at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22584">
        <property type="entry name" value="Rcat_RBR_unk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003467054" description="RBR-type E3 ubiquitin transferase" evidence="12">
        <location>
            <begin position="24"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="317"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="321"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="167"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="659"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="516"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="732"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="663"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA46155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="812" mass="90620" checksum="D0485A57DC7FFF31" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G5EGX4</accession>
    <name>G5EGX4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Laccase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGCH7_ch7g635</name>
        <name evidence="11" type="ORF">MGG_02876</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15</strain>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720855.1">
        <property type="nucleotide sequence ID" value="XM_003720807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EGX4"/>
    <dbReference type="SMR" id="G5EGX4"/>
    <dbReference type="STRING" id="242507.G5EGX4"/>
    <dbReference type="GeneID" id="2682429"/>
    <dbReference type="KEGG" id="mgr:MGG_02876"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02876"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_3_1_1"/>
    <dbReference type="OMA" id="DHSKMAM"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13854">
        <property type="entry name" value="CuRO_1_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13880">
        <property type="entry name" value="CuRO_2_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13901">
        <property type="entry name" value="CuRO_3_MaLCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000021">
        <property type="entry name" value="Extracellular dihydrogeodin oxidase/laccase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000038">
        <property type="entry name" value="Extracellular dihydrogeodin oxidase/laccase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF145">
        <property type="entry name" value="LCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="84"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="211"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="451"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EAQ71228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA46112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="595" mass="64519" checksum="0D1CC687DEAD33F4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH62</accession>
    <name>G5EH62_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g644</name>
        <name evidence="2" type="ORF">MGG_17941</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720847.1">
        <property type="nucleotide sequence ID" value="XM_003720799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH62"/>
    <dbReference type="GeneID" id="12984816"/>
    <dbReference type="KEGG" id="mgr:MGG_17941"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17941"/>
    <dbReference type="HOGENOM" id="CLU_2264278_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ71237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="103" mass="11355" checksum="3A1DD10527549010" modified="2011-12-14" version="1">MSESTHTLYIHGTHHTNGGAAMVRSPTSGDFLKYIFSTVRYLLIGRDAGKQMFQLVSQQNISSRVFVRPIVLSADGAPWRYMRSKTGRGSAGIVLQDRIKGIG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-10-19" modified="2025-06-18" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4R713</accession>
    <accession>G4N8P1</accession>
    <name>GATB_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial</fullName>
            <shortName evidence="1">Glu-AdT subunit B</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ORF">MGG_03390</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716554.1">
        <property type="nucleotide sequence ID" value="XM_003716506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R713"/>
    <dbReference type="SMR" id="A4R713"/>
    <dbReference type="FunCoup" id="A4R713">
        <property type="interactions" value="358"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4R713"/>
    <dbReference type="EnsemblFungi" id="MGG_03390T0">
        <property type="protein sequence ID" value="MGG_03390T0"/>
        <property type="gene ID" value="MGG_03390"/>
    </dbReference>
    <dbReference type="GeneID" id="2676881"/>
    <dbReference type="KEGG" id="mgr:MGG_03390"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03390"/>
    <dbReference type="eggNOG" id="KOG2438">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019240_4_1_1"/>
    <dbReference type="InParanoid" id="A4R713"/>
    <dbReference type="OMA" id="ARKWWMG"/>
    <dbReference type="OrthoDB" id="1722066at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="GatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004012">
        <property type="entry name" value="PRK05477.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF0">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0809">Transit peptide</keyword>
    <feature type="transit peptide" description="Mitochondrion" evidence="1">
        <location>
            <begin position="1"/>
            <end position="8"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000413261" description="Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial">
        <location>
            <begin position="9"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="654" mass="72313" checksum="9CFF2D7E57EFEA06" modified="2007-05-15" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-10-23" modified="2025-06-18" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>A4RA36</accession>
    <accession>G4N219</accession>
    <name>LOC1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>60S ribosomal subunit assembly/export protein LOC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">LOC1</name>
        <name type="ORF">MGG_07529</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for efficient assembly and nuclear export of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the 66S pre-ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the LOC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711442.1">
        <property type="nucleotide sequence ID" value="XM_003711394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RA36"/>
    <dbReference type="SMR" id="A4RA36"/>
    <dbReference type="FunCoup" id="A4RA36">
        <property type="interactions" value="321"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RA36"/>
    <dbReference type="EnsemblFungi" id="MGG_07529T0">
        <property type="protein sequence ID" value="MGG_07529T0"/>
        <property type="gene ID" value="MGG_07529"/>
    </dbReference>
    <dbReference type="GeneID" id="2683449"/>
    <dbReference type="KEGG" id="mgr:MGG_07529"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07529"/>
    <dbReference type="eggNOG" id="ENOG502RY6R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096593_0_0_1"/>
    <dbReference type="InParanoid" id="A4RA36"/>
    <dbReference type="OMA" id="RESMNTI"/>
    <dbReference type="OrthoDB" id="1743802at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037650">
        <property type="entry name" value="Loc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28028">
        <property type="entry name" value="60S RIBOSOMAL SUBUNIT ASSEMBLY/EXPORT PROTEIN LOC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28028:SF1">
        <property type="entry name" value="60S RIBOSOMAL SUBUNIT ASSEMBLY_EXPORT PROTEIN LOC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0175">Coiled coil</keyword>
    <keyword id="KW-0509">mRNA transport</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000308797" description="60S ribosomal subunit assembly/export protein LOC1">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="141"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="129"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="199" mass="21911" checksum="077F894CDD4D6CE0" modified="2007-05-15" version="1">MGIARTKTIKNKHSAKLANLRNNKSSSSQADGGNFVRAKKSGTGSNKPPLTSQAKGRPSIADLLKKKKKRVYTEKELGVPKLNMITPVGVEKPKGKKKGKVFVDDPESINTILAIVQAEKEGQIESKIMKARQMEEIREARRVEAEKKEAERQAKLEDTKNSLRKKRSRSNKTEDDGVSELAATGSKATKAKKKKVAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKB4</accession>
    <name>G4MKB4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Juvenile hormone epoxide hydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_02509</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709317.1">
        <property type="nucleotide sequence ID" value="XM_003709269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKB4"/>
    <dbReference type="SMR" id="G4MKB4"/>
    <dbReference type="STRING" id="242507.G4MKB4"/>
    <dbReference type="GeneID" id="2681606"/>
    <dbReference type="KEGG" id="mgr:MGG_02509"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02509"/>
    <dbReference type="eggNOG" id="KOG2565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_2_1"/>
    <dbReference type="InParanoid" id="G4MKB4"/>
    <dbReference type="OMA" id="YSAMMVT"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA56705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="413" mass="45876" checksum="8617F2F9E4C79F9A" modified="2011-12-14" version="1">MTSEVRPFKIAVPEGELTKLKCKLNAASFPPDTAFSDDWERGSPQADVKRLVARWKEGFDWRAAEAELNKIPQFTTSVDVDGFGSIEMHFVHQRSQDENAIPLLFCHGWPGGFWEVRKLLPLLTPQNVGEPSFHVVAPSHPNFGFSEEVAKPGFNGRKYAEAAHKVMLRLGYDKYVTQGGDWGYRITRALDLLYPENVLASHINMILADPPTLLQHPMLYLRALLTPHTAPEKAMLANVKKLMDKGMGYNLQQSTKPATIGFALADSPVALLAWQYEKLIGWSDDDYRWGDDEVLTWASLYIFSRPGPAASVRIYYEDTLGDDGFGDASGGIKESKRWNGAVPLGLSSFPRDMGALISSGRTLGPVVFERAHERGGHFPATERPEVLAGDLKDMFSLSPGGFGRAVQDRLKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKR5</accession>
    <name>G4MKR5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709367.1">
        <property type="nucleotide sequence ID" value="XM_003709319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKR5"/>
    <dbReference type="SMR" id="G4MKR5"/>
    <dbReference type="STRING" id="242507.G4MKR5"/>
    <dbReference type="GeneID" id="2684833"/>
    <dbReference type="KEGG" id="mgr:MGG_06660"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06660"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="InParanoid" id="G4MKR5"/>
    <dbReference type="OMA" id="VIMLCKT"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000173">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier protein] reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF127">
        <property type="entry name" value="3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="258" mass="27571" checksum="9505AAF04B050FFD" modified="2011-12-14" version="1">MSVDNNLVGRLALITGASGGIGAAIAKDLWSHGSSLALTYWSSREKIDALVAELEKSSTRSNTRISVHRIDMGTPNDQDFDLLFQEIVQLQGQSPSILVANAGYGKRFTYIEDIELAEFDYMMRVNLRAPFILAKQCVPDMAKNKWGRLIFISSIAAYGGGINGPHYAASKGGVTSMMRNLSARYAKDGITANDVAPAMIGETGMIPNARAVEGTAGDVRNIPVGRLGAPQEVANAVTMLCRTGYLTGQSIVLSGGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKZ0</accession>
    <name>G4MKZ0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710237.1">
        <property type="nucleotide sequence ID" value="XM_003710189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKZ0"/>
    <dbReference type="SMR" id="G4MKZ0"/>
    <dbReference type="STRING" id="242507.G4MKZ0"/>
    <dbReference type="GeneID" id="2676085"/>
    <dbReference type="KEGG" id="mgr:MGG_13036"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13036"/>
    <dbReference type="eggNOG" id="ENOG502SKDP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_836965_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKZ0"/>
    <dbReference type="OMA" id="HGHGTIM"/>
    <dbReference type="OrthoDB" id="5093543at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="36859" checksum="B6DB9C239F0A81AB" modified="2011-12-14" version="1">MADSHQCSSRDDSYIEMEKQMTSKACKWNHTGMGHGIIMSNMIARINPMVSLAVLKLWDGFAPDWTRIIYSEAAAQAIRCDVCRKVYVIPMSWTMRPKTSIKASKDQSTPTDASMNRGEAGASQQATIDRQTMAIRELEQRIEEVDESGIIMFCSASDDIAVGETLLFCRKPNSIIRIGGAMQYGQRDPISEDPDSISYYFPGNQVAEAWNPLRDASKVRYQGGSSVGKALAAGLASVVIHCAIMLRNGRPVASPQYPDAQALVEALRKTGNMRLSFDSVSEVDDETEGWRKSKYLSVWALFGKAAEMESLRDYERWGVLAGLMKRISAMIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML28</accession>
    <name>G4ML28_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial import receptor subunit tom-40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_08637</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711067.1">
        <property type="nucleotide sequence ID" value="XM_003711019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML28"/>
    <dbReference type="SMR" id="G4ML28"/>
    <dbReference type="FunCoup" id="G4ML28">
        <property type="interactions" value="809"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ML28"/>
    <dbReference type="GeneID" id="2678871"/>
    <dbReference type="KEGG" id="mgr:MGG_08637"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08637"/>
    <dbReference type="eggNOG" id="KOG3296">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042174_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML28"/>
    <dbReference type="OMA" id="TRFNYRW"/>
    <dbReference type="OrthoDB" id="19656at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07305">
        <property type="entry name" value="Porin3_Tom40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037930">
        <property type="entry name" value="Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10802">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA58455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="355" mass="38355" checksum="4240845D2C8E1BE0" modified="2011-12-14" version="1">MASATLDIMRNNPLTASVADVYSSFHERRAKLGLTNPGTVENLAKEVQRDVFTNNYAFSGLRGDFTRAFNLNPLFQVSHNFAVGERMPPYTFAAMYGSSKVFMQGSVDNDMQVNARFNWRWSDALVSKTQFSLGTGNQDMAHLESEYTGSDFTTSIKALNPSFFEGGLTGIFMGSYMQSVTKKLALGMEGVWQRAALSQPPDTVMSYVAKYKSDDWIATGQLAGAGALSTTFWRKISEKCQAGIEMTLSLAPGDPAGGMMMGGPSIQAEGVTTAAVKYDFRMSTLRMQVDTKGKMTCLAEKRIAPAIMMTIAAEVDHPTGAAKLGLGVSLESGGEELQERQEALGAAAPSPNIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML44</accession>
    <name>G4ML44_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_06685</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="12">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the cytochrome c family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709392.1">
        <property type="nucleotide sequence ID" value="XM_003709344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML44"/>
    <dbReference type="SMR" id="G4ML44"/>
    <dbReference type="FunCoup" id="G4ML44">
        <property type="interactions" value="570"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ML44"/>
    <dbReference type="GeneID" id="2684858"/>
    <dbReference type="KEGG" id="mgr:MGG_06685"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06685"/>
    <dbReference type="eggNOG" id="KOG3453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060944_3_0_1"/>
    <dbReference type="InParanoid" id="G4ML44"/>
    <dbReference type="OMA" id="KARCAQC"/>
    <dbReference type="OrthoDB" id="449280at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000001">
        <property type="entry name" value="Cytochrome c iso-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10 12" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="13">
        <location>
            <begin position="6"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA56780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="108" mass="11923" checksum="F84A730C4EC33B42" modified="2011-12-14" version="1">MGFSEGNAKNGAKLFKTRCEQCHTVDAAGGNKIGPALHGLFGRKTGSVDGYAYTDANKQKGITWDENTLFDYLENPKKYIPGTKMAFGGLKKEKDRNDLITFLKENTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLC4</accession>
    <name>G4MLC4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710266.1">
        <property type="nucleotide sequence ID" value="XM_003710218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLC4"/>
    <dbReference type="GeneID" id="12986266"/>
    <dbReference type="KEGG" id="mgr:MGG_16354"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16354"/>
    <dbReference type="HOGENOM" id="CLU_2638526_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLC4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="77" mass="8479" checksum="6A39DEECBE5BC5D8" modified="2011-12-14" version="1">MPSLTGILQAMTAEQKDGRREIFIRNGCVFSKVDLGNTDLTAFLGNRGSSYRGFDPALQGPARRDSRSNGTDQTVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLC9</accession>
    <name>G4MLC9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710271.1">
        <property type="nucleotide sequence ID" value="XM_003710223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLC9"/>
    <dbReference type="STRING" id="242507.G4MLC9"/>
    <dbReference type="GeneID" id="2675996"/>
    <dbReference type="KEGG" id="mgr:MGG_05411"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05411"/>
    <dbReference type="eggNOG" id="ENOG502STM3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012879_2_0_1"/>
    <dbReference type="InParanoid" id="G4MLC9"/>
    <dbReference type="OMA" id="WIETERA"/>
    <dbReference type="OrthoDB" id="4586478at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="591"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="715" mass="78668" checksum="1AC3812FEE951314" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLP1</accession>
    <name>G4MLP1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_06770</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709486.1">
        <property type="nucleotide sequence ID" value="XM_003709438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLP1"/>
    <dbReference type="SMR" id="G4MLP1"/>
    <dbReference type="STRING" id="242507.G4MLP1"/>
    <dbReference type="GeneID" id="2684943"/>
    <dbReference type="KEGG" id="mgr:MGG_06770"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06770"/>
    <dbReference type="eggNOG" id="KOG2684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_3_1_1"/>
    <dbReference type="InParanoid" id="G4MLP1"/>
    <dbReference type="OMA" id="IRTKPEY"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="96"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA56874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="315" mass="33541" checksum="F91A5A2789E8347C" modified="2011-12-14" version="1">MAPKSSIEEFQDLLAGIVSKSKDGKGGRGRMLAILGAGLAAPSGLPTMRGPGGLWQRKTAAVSEPTNRTDLEMVWLYYAWRHHLTAGASPNAAHKALASLARHRHPQTSSSTTAAPPTKDGESAASSLPGFELMCLNLSLDDLLVRAGYPPESLRAAFGSNMALVCTDTSTCSAVRRTSTTDRPCPSLVSESDEPPRWLTDPTLAVPDLEPSRFPHCAACGKHLVRPTVQPNRQALADVDDFVARKPAVDVALVVGTAAVLPPAPRYLHETMRHGAVVVVVNPDPAVAEGLRDEDFFFQGDAAEILPRLFGKVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM68</accession>
    <name>G4MM68_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_13087</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710361.1">
        <property type="nucleotide sequence ID" value="XM_003710313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM68"/>
    <dbReference type="GeneID" id="2676103"/>
    <dbReference type="KEGG" id="mgr:MGG_13087"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13087"/>
    <dbReference type="HOGENOM" id="CLU_2197471_0_0_1"/>
    <dbReference type="InParanoid" id="G4MM68"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="108" mass="10975" checksum="CD9EC88020FDEC90" modified="2011-12-14" version="1">MLGATAPAFTLYALQVSAGGAGVGAAQNGAVAPRVGAAPAQGGSARVEYNKDEYYNRCKAVLKEPGPRATTGARPTPCIPCPARRLSSRCRAATTSSSSPARIARATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM90</accession>
    <name>G4MM90_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05519</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710383.1">
        <property type="nucleotide sequence ID" value="XM_003710335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM90"/>
    <dbReference type="SMR" id="G4MM90"/>
    <dbReference type="STRING" id="242507.G4MM90"/>
    <dbReference type="GeneID" id="2675857"/>
    <dbReference type="KEGG" id="mgr:MGG_05519"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05519"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_0_0_1"/>
    <dbReference type="InParanoid" id="G4MM90"/>
    <dbReference type="OMA" id="MVPLENC"/>
    <dbReference type="OrthoDB" id="5407715at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350">
        <property type="entry name" value="NAD-DEPENDENT ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43350:SF17">
        <property type="entry name" value="NAD-DEPENDENT ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="6">
        <location>
            <begin position="55"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA57771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="393" mass="42062" checksum="45F2B332679A3CF0" modified="2011-12-14" version="1">MPTTKRVSFVSLPETNTPKDAADEVPTQHRALVFTSTATGLELKTVPTPRNPQLGTALVRVEAATILSYQGGIYNGTRQYPQIASPHSGGYSGVGRIAAVGADATTLRVGQFVFADCDVRARDGDGWFLVGTQTACDAGARRVNDEVYRDGAFAEYFTVPLENCHPLDEPRLTRELGYSVADVAYMSYLLVAYGGLRDVGLEPGETVVIAPATGGFGGAGVLTALAMGARVVAMGRSEQELARLKVHAAAGYPGRDDMVETVRITDDEAGIAAQLRALGTIDAVLDFSPPEAEGSCYLRCAIRSLRPKGRVSLMGFSTDFADHAVVMNSLCLRGKVMYERDDVSRFVKLLERGLFPRGKDFVDTKVFRLDQANEALDAAAEHAGCGRSVVFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNC2</accession>
    <name>G4MNC2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA56245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003708809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNC2"/>
    <dbReference type="GeneID" id="12985698"/>
    <dbReference type="KEGG" id="mgr:MGG_16032"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16032"/>
    <dbReference type="HOGENOM" id="CLU_2705284_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNC2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="73" mass="7784" checksum="B31E802E5D68C154" modified="2011-12-14" version="1">MRGAGMEKWLRTGREILFWVFAPLAKRVAIDAESTISDGPAPLGSLTFLITPAVIASPTSQSLPSPARFTIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNC3</accession>
    <name>G4MNC3_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">PHO85 cyclin-6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708858.1">
        <property type="nucleotide sequence ID" value="XM_003708810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNC3"/>
    <dbReference type="FunCoup" id="G4MNC3">
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    </dbReference>
    <dbReference type="STRING" id="242507.G4MNC3"/>
    <dbReference type="GeneID" id="2681243"/>
    <dbReference type="KEGG" id="mgr:MGG_02088"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02088"/>
    <dbReference type="eggNOG" id="KOG1674">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013692_2_0_1"/>
    <dbReference type="InParanoid" id="G4MNC3"/>
    <dbReference type="OMA" id="PMRGEGM"/>
    <dbReference type="OrthoDB" id="1060854at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
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    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005979">
        <property type="term" value="P:regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005981">
        <property type="term" value="P:regulation of glycogen catabolic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF94">
        <property type="entry name" value="PHO85 CYCLIN-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="67"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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        </location>
    </feature>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="237"/>
        </location>
    </feature>
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            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="437"/>
            <end position="452"/>
        </location>
    </feature>
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        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="613" mass="65670" checksum="83FABA124D57608F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    <organism evidence="2 3">
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            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709668.1">
        <property type="nucleotide sequence ID" value="XM_003709620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNE2"/>
    <dbReference type="GeneID" id="2685102"/>
    <dbReference type="KEGG" id="mgr:MGG_06929"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06929"/>
    <dbReference type="eggNOG" id="ENOG502SUW6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="InParanoid" id="G4MNE2"/>
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    <proteinExistence type="predicted"/>
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            <begin position="25"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="218" mass="24018" checksum="865CDE3255050A58" modified="2011-12-14" version="1">MDSVSPRTLEALGYMPSLVRSASSVVMVSITTLISLVSTTVAAAVALLRFSLIPVSWLWRVVFVLLSPVLYTTAYVLSPAWYIISFLPKLQPLYIYFGSAAFVGILAGLSIKLSSHVFVSVLELDKESPPSLKQIEAQRQKKQKQKLALSAATTPTAQQTPTIKRASDYYSGSLSSDIDWQIIDRITNRGLHSEHSRRMPLLQSIILEEEEDDTSGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNV8</accession>
    <name>G4MNV8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_16231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fructosamine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709727.1">
        <property type="nucleotide sequence ID" value="XM_003709679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNV8"/>
    <dbReference type="SMR" id="G4MNV8"/>
    <dbReference type="STRING" id="242507.G4MNV8"/>
    <dbReference type="GeneID" id="12985252"/>
    <dbReference type="KEGG" id="mgr:MGG_16231"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16231"/>
    <dbReference type="eggNOG" id="KOG3021">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036517_0_3_1"/>
    <dbReference type="InParanoid" id="G4MNV8"/>
    <dbReference type="OMA" id="RECDIAM"/>
    <dbReference type="OrthoDB" id="5772781at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102193">
        <property type="term" value="F:protein-ribulosamine 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1200.10:FF:000018">
        <property type="entry name" value="Fructosamine-3-kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF8">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="323" mass="34735" checksum="F39841C4198E0AB2" modified="2011-12-14" version="1">MMAPSLDPAILKALGLDAETTNMSTHGGSGFASTFKLCGTVNGREKTFFVKTGSGKDAETMFRGEHASLNAIHSAVPNFCPASHAYGAMSSEGRFFMATDFLDLGGRGASGTGKSLAAKLAQLHTTPAPVPDGFDKPMFGFPVPTCCGSTVQDNSWKESWAEFYADNRLRHILAAGIKSNGKDAELERTVETVASRVVPRLLGDGHLKGVKPVVIHGDLWSGNHGAGRFAGSDGGVEEVVYDPSCVYGHSEYELGIMNMFGGFGSRFWEEYGKLVPKSEPVEEFEDRVALYELYHHLNHFALFGGGYRGGAMSIMKKLISKYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ85</accession>
    <name>G4MQ85_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709890.1">
        <property type="nucleotide sequence ID" value="XM_003709842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQ85"/>
    <dbReference type="GeneID" id="12985283"/>
    <dbReference type="KEGG" id="mgr:MGG_16261"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16261"/>
    <dbReference type="HOGENOM" id="CLU_2740514_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQ85"/>
    <dbReference type="OMA" id="VVMIIRT"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="71" mass="8109" checksum="D720353C7FFB6D8D" modified="2011-12-14" version="1">MVPCGRPERQEAEEGSIDLQLQATRERLAHHLCGVVMIIRTLVKQTNPFQGGNHFRAKPPSGKCRERREDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQK2</accession>
    <name>G4MQK2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Retinol dehydrogenase 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_02337</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709104.1">
        <property type="nucleotide sequence ID" value="XM_003709056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQK2"/>
    <dbReference type="SMR" id="G4MQK2"/>
    <dbReference type="STRING" id="242507.G4MQK2"/>
    <dbReference type="GeneID" id="2681434"/>
    <dbReference type="KEGG" id="mgr:MGG_02337"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02337"/>
    <dbReference type="eggNOG" id="KOG1205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_9_1"/>
    <dbReference type="InParanoid" id="G4MQK2"/>
    <dbReference type="OMA" id="QFRAFIT"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051911">
        <property type="entry name" value="SDR_oxidoreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43976:SF16">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA56492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="278" mass="30257" checksum="D8AF89C4F18E5B0E" modified="2011-12-14" version="1">MAQQLLAYPEYRVVATVRNPSSLADLEGGDDRLLTTALEVTSKESRDAAVAAALAKFGRIDVFVNNAGQAFHSDSEQSCPEEERQQFDVNFWGPMELTRHAVRVMREENPKNGPIGGVIINVTSFVGFVSIPGCPFYCASKFALEGFTETFAKEVHPDWNIHFCLAEPGGVATAFADNRKFGVPHPAYQAPGTPTREFEAWAQNLSDMGFSTAEGTAKAIIEAVHGAKEGARGRIPLRLPTGSDSFHMIKREVDNIAANLNEFQQVSLIPSNQVTAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQK8</accession>
    <name>G4MQK8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_11948</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709110.1">
        <property type="nucleotide sequence ID" value="XM_003709062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQK8"/>
    <dbReference type="SMR" id="G4MQK8"/>
    <dbReference type="STRING" id="242507.G4MQK8"/>
    <dbReference type="GeneID" id="5049734"/>
    <dbReference type="KEGG" id="mgr:MGG_11948"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11948"/>
    <dbReference type="eggNOG" id="ENOG502SING">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_4_3_1"/>
    <dbReference type="InParanoid" id="G4MQK8"/>
    <dbReference type="OMA" id="EWANYMN"/>
    <dbReference type="OrthoDB" id="5271017at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF10">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465207" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="17">
        <location>
            <begin position="22"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Auxiliary Activity family 9 catalytic" evidence="18">
        <location>
            <begin position="22"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA56498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="272" mass="28852" checksum="BF79289AE9479181" modified="2011-12-14" version="1">MHCNTLATIVAAVGLIPTALAHYNFESLVVNGKSTGPYEYVRRTTNSNSPIEDVKSQNMVCNQGGLDASIMAATKTYTVAPGDEVGFLVNSNLGHPGPQAVYLSRAPDGVAANQYKGDGDWFKVYSLTSGKIDANTGIDWATFPGSQGASSFTFKLPQNLPPGDYLMRAEHIGLHGAGTFGGAQFYIGCAQLKVTGSGSGKPGPTVKFPGAYTGNEPGIKINIYWPPLTSYTPPGPVTWPNACEDHTTNLFGKPSDGDCTPLRSSRRRSAHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR53</accession>
    <name>G4MR53_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">F-actin-capping protein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_09902</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the F-actin capping complex, composed of a heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the F-actin-capping protein beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709997.1">
        <property type="nucleotide sequence ID" value="XM_003709949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR53"/>
    <dbReference type="SMR" id="G4MR53"/>
    <dbReference type="FunCoup" id="G4MR53">
        <property type="interactions" value="873"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MR53"/>
    <dbReference type="GeneID" id="2680872"/>
    <dbReference type="KEGG" id="mgr:MGG_09902"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09902"/>
    <dbReference type="eggNOG" id="KOG3174">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045864_1_0_1"/>
    <dbReference type="InParanoid" id="G4MR53"/>
    <dbReference type="OMA" id="WSNKYYP"/>
    <dbReference type="OrthoDB" id="9979678at2759"/>
    <dbReference type="PHI-base" id="PHI:7188"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099079">
        <property type="term" value="C:actin body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000142">
        <property type="term" value="C:cellular bud neck contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005934">
        <property type="term" value="C:cellular bud tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000131">
        <property type="term" value="C:incipient cellular bud site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030447">
        <property type="term" value="P:filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904600">
        <property type="term" value="P:mating projection actin fusion focus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902404">
        <property type="term" value="P:mitotic actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.570:FF:000001">
        <property type="entry name" value="F-actin-capping protein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.210:FF:000005">
        <property type="entry name" value="F-actin-capping protein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001698">
        <property type="entry name" value="CAPZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043175">
        <property type="entry name" value="CAPZB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019771">
        <property type="entry name" value="F-actin_capping_bsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01115">
        <property type="entry name" value="F_actin_cap_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00192">
        <property type="entry name" value="FACTINCAPB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00231">
        <property type="entry name" value="F_ACTIN_CAPPING_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0117">Actin capping</keyword>
    <keyword evidence="6 10" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="74"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA57385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="288" mass="31618" checksum="E6A51D8882B083A5" modified="2011-12-14" version="1">MAADPFDSALDLLRRLDPKHTTRHLNGLMTIVPDLTEDLLSSVDQPLTVRRCKQTGREYLLCDYNRDGDSYRSPWSNEFDPPLDDGPGGLGGVGPQGGNEGAGELGVPGERVRKMEVKANEAFDVYRDLYYEGGVSSVYLWNLDDGFAGVVLLKKAAPQGGNNEGVWDSIHVFEASERGRSTTYRLTSTVILTLSAGGGDSALGDMNLSGNMTRQLEQDMRTAEGDESHIANLGRLVEDMELKMRNLLQEVYFGKAKDVVGDLRSLGSLSEGQRDRDAQREIIGSMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRB2</accession>
    <name>G4MRB2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">15-hydroxyprostaglandin dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_04683</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710849.1">
        <property type="nucleotide sequence ID" value="XM_003710801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRB2"/>
    <dbReference type="SMR" id="G4MRB2"/>
    <dbReference type="GeneID" id="2678130"/>
    <dbReference type="KEGG" id="mgr:MGG_04683"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04683"/>
    <dbReference type="eggNOG" id="KOG4169">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_13_0_1"/>
    <dbReference type="InParanoid" id="G4MRB2"/>
    <dbReference type="OMA" id="WAKWERI"/>
    <dbReference type="OrthoDB" id="5371740at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA58237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="304" mass="33719" checksum="76FDE6BE3DAAFCF4" modified="2011-12-14" version="1">MAPTTASDRKTAIITGSTSGIGLDLARDLRAKGWNVAISGRREPCKGEEIAKSIDETGEAALYCRADVSVYADQAELFRQAWAKWGRLDLFVANAGIVDEGPTSRYNLLRKDAAVDDVPPEPKLGCSDVNFKGVVYGTELAQHYMRHNKPKRGGKIIVTGSIAGLFPLPTYPEYSSAKAAVSQWVRVMAPMLKLHDDITINCVLPNGYDTAILPGFKEAYLDEHLTKRDCMMRAYFIFIDDEENSQTGQNVETAYDSLYFHERPAAKNEVVKRTEKVYEPWFEYAHGARSGLETAIKAPMRTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS37</accession>
    <name>G4MS37_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10507</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA57503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003710067.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MS37"/>
    <dbReference type="SMR" id="G4MS37"/>
    <dbReference type="GeneID" id="2682119"/>
    <dbReference type="KEGG" id="mgr:MGG_10507"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10507"/>
    <dbReference type="eggNOG" id="ENOG502QQ9Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006273_0_0_1"/>
    <dbReference type="InParanoid" id="G4MS37"/>
    <dbReference type="OMA" id="ATIWIGE"/>
    <dbReference type="OrthoDB" id="10258955at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="CDD" id="cd01309">
        <property type="entry name" value="Met_dep_hydrolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Amidohydro_3"/>
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        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
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        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
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        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase 3" evidence="3">
        <location>
            <begin position="491"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA57503.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSI2</accession>
    <name>G4MSI2_PYRO7</name>
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        <submittedName>
            <fullName evidence="11">Sexual differentiation process protein isp4</fullName>
        </submittedName>
    </protein>
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        <name evidence="11" type="ORF">MGG_01452</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
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        <property type="protein sequence ID" value="EHA54598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714405.1">
        <property type="nucleotide sequence ID" value="XM_003714357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSI2"/>
    <dbReference type="GeneID" id="2679704"/>
    <dbReference type="KEGG" id="mgr:MGG_01452"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01452"/>
    <dbReference type="eggNOG" id="KOG2262">
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    <dbReference type="HOGENOM" id="CLU_004965_4_1_1"/>
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    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
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    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="490"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="527"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="557"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="736"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="763"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="793"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="841"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="917"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="955"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="997"/>
            <end position="1016"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="284"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="687"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="687"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA54598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1056" mass="116595" checksum="57BFE698279BC6E9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSI5</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714408.1">
        <property type="nucleotide sequence ID" value="XM_003714360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSI5"/>
    <dbReference type="GeneID" id="2679707"/>
    <dbReference type="KEGG" id="mgr:MGG_01455"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01455"/>
    <dbReference type="HOGENOM" id="CLU_1441314_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSI5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465363" evidence="1">
        <location>
            <begin position="23"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="188" mass="20814" checksum="364525E4C3064D95" modified="2011-12-14" version="1">MLGKSFVFGSLVAFSLLNNVAATTTEELFVMGLGTTIPPNARKGNVGLGDYGGLNPNAVSHLPEKDTKVKLSDQPNRLVSYYKKKDPDATYYVYGIDKNEEALKFALWDMMNGKALNALPAHGGNEVPQEQLDYSAKYVVKKAPIPWHMIKGWWIAAPGHDSTEFHPNPGYSKVPSASLMRKLKFWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT73</accession>
    <name>G4MT73_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CCCH zinc finger and RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_07147</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the turnover of nuclear polyadenylated (pA+) RNA.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715345.1">
        <property type="nucleotide sequence ID" value="XM_003715297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT73"/>
    <dbReference type="SMR" id="G4MT73"/>
    <dbReference type="STRING" id="242507.G4MT73"/>
    <dbReference type="GeneID" id="2683269"/>
    <dbReference type="KEGG" id="mgr:MGG_07147"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07147"/>
    <dbReference type="eggNOG" id="KOG2135">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017928_1_0_1"/>
    <dbReference type="InParanoid" id="G4MT73"/>
    <dbReference type="OMA" id="ITYDSHA"/>
    <dbReference type="OrthoDB" id="443401at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12257">
        <property type="entry name" value="RRM1_RBM26_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1390.10:FF:000007">
        <property type="entry name" value="CCCH zinc finger and RRM domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000647">
        <property type="entry name" value="CCCH zinc finger and RRM domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045137">
        <property type="entry name" value="RBM26/27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398">
        <property type="entry name" value="RNA RECOGNITION RRM/RNP DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN SWM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="332"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="294"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="406"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="488"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="703"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="517"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="703"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="734"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="745"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA55538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="766" mass="83763" checksum="01C4F5141EA97376" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTM5</accession>
    <name>G4MTM5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MKI67 FHA domain-interacting nucleolar phosphoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_12370</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715390.1">
        <property type="nucleotide sequence ID" value="XM_003715342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTM5"/>
    <dbReference type="SMR" id="G4MTM5"/>
    <dbReference type="STRING" id="242507.G4MTM5"/>
    <dbReference type="GeneID" id="2683169"/>
    <dbReference type="KEGG" id="mgr:MGG_12370"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12370"/>
    <dbReference type="eggNOG" id="KOG4208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025741_5_0_1"/>
    <dbReference type="InParanoid" id="G4MTM5"/>
    <dbReference type="OMA" id="WKGANKR"/>
    <dbReference type="OrthoDB" id="21467at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12307">
        <property type="entry name" value="RRM_NIFK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46754">
        <property type="entry name" value="MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="168"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA55583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="378" mass="40928" checksum="109B2A39AF1D5E07" modified="2011-12-14" version="1">MAAAVSKKGRATRAKPAAQAADSPKAAVESPQPAKRKAESEASPVVTKKAKAEKNKKAVAAATTTSSDKEKTAQKKSATTPTKASSTKAVKKAEKEEVVAEEEIALDDDNDSEEEREDQALVTKLGFEVSDDEEEGGDYTAGTDVGKVPKVSTKVKKSAQAGSSDGPRVIYIGHIPYGFFEHEIRQYLSQFGTITNLRLSRNKKTGASKGYAFVEFQDASTAAIVAKTMDAYLLFGRILKVKLVPRESQHDNLFKGANRRFKKVPWTKMAGKELEKPKGEARWGKAVEKENRRRSGRLEKLRELMGYEFEAPAVKPAVAAIEAKKTAEIEAPKEVEEKPKAIEAPPAAEKESVVEAANSPAAKPAKTTKAKKGRKAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTW7</accession>
    <name>G4MTW7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATPase inhibitor, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_01589</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Inhibits the enzyme activity of ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ATPase inhibitor family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714568.1">
        <property type="nucleotide sequence ID" value="XM_003714520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTW7"/>
    <dbReference type="SMR" id="G4MTW7"/>
    <dbReference type="STRING" id="242507.G4MTW7"/>
    <dbReference type="GeneID" id="2679303"/>
    <dbReference type="KEGG" id="mgr:MGG_01589"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01589"/>
    <dbReference type="eggNOG" id="ENOG502SCJG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145563_0_1_1"/>
    <dbReference type="InParanoid" id="G4MTW7"/>
    <dbReference type="OMA" id="NQGGEHN"/>
    <dbReference type="OrthoDB" id="5532350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042030">
        <property type="term" value="F:ATPase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007648">
        <property type="entry name" value="ATPase_inhibitor_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04568">
        <property type="entry name" value="IATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64602">
        <property type="entry name" value="F1 ATPase inhibitor, IF1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA54761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="100" mass="11225" checksum="08AFD581DC61C716" modified="2011-12-14" version="1">MLRQSFTKVARPAVRLSNARVAFSTSAIRMAEGDLGSTPKTGGGDAFQKRERAQEDYAIRQREKEKLLELKKKLAEQQAHLNKLSEHIDELTKSQGGEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU40</accession>
    <name>G4MU40_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="5 11">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_07229</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
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            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the NMT family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="5 11"/>
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        <property type="protein sequence ID" value="EHA55640.1"/>
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        <property type="nucleotide sequence ID" value="XM_003715399.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_07229"/>
    <dbReference type="eggNOG" id="KOG2779">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_022882_2_0_1"/>
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    <dbReference type="OMA" id="GWKRDWH"/>
    <dbReference type="OrthoDB" id="60315at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
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    <dbReference type="InterPro" id="IPR000903">
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        <property type="entry name" value="NMT_C"/>
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    <dbReference type="InterPro" id="IPR022678">
        <property type="entry name" value="NMT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
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    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00976">
        <property type="entry name" value="NMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="14">
        <location>
            <begin position="178"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="15">
        <location>
            <begin position="346"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022240"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048276"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA55640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="563" mass="63181" checksum="47EAE6B3F906ED5D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUB3</accession>
    <name>G4MUB3_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01621</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_01621"/>
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        <property type="entry name" value="Cisplatin_resist-associated"/>
    </dbReference>
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        <property type="entry name" value="DUF3602"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN PAR32"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR34693:SF1">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
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            <end position="148"/>
        </location>
    </feature>
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        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="148" mass="15529" checksum="CF6458AAEC268D69" modified="2011-12-14" version="1">MSAFTSSGRGGAGNIVDKTKSPRIEPKDLETPTLKTSVVTTGRGGTGNMAKNVDPAETRAMQDVSPVPRQELSGGTHIGRGGTGNVFKPKPEDEEMGNVQHNAEKPQEGGGKEPQQAAQGDAVGFEEQDKADNQGLAAKGKQWLFGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUK9</accession>
    <name>G4MUK9_PYRO7</name>
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        <recommendedName>
            <fullName evidence="5">HDA1 complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07282</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715508.1">
        <property type="nucleotide sequence ID" value="XM_003715460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUK9"/>
    <dbReference type="SMR" id="G4MUK9"/>
    <dbReference type="FunCoup" id="G4MUK9">
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    </dbReference>
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    <dbReference type="KEGG" id="mgr:MGG_07282"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07282"/>
    <dbReference type="eggNOG" id="ENOG502S6DU">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_017708_0_0_1"/>
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    <dbReference type="OMA" id="GDYWLPT"/>
    <dbReference type="OrthoDB" id="3647690at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
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        <property type="entry name" value="HDA1_su2/3_sf"/>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="451"/>
            <end position="495"/>
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    </feature>
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        <location>
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        <location>
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            <end position="705"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="2">
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            <begin position="467"/>
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        <source>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
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    </evidence>
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        <source>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA54893.1"/>
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            <end position="76"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA54893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="314" mass="33383" checksum="F7F5BA0BD1C9592E" modified="2011-12-14" version="1">MNGNTGTGRKQAAIVAATAAAAVVSSPAAFSKPDMPTSSSKSQRVWNTKNLGWRLAADAISAAAAATMVAPLISIIDRSIMENASGRRSLIESVKSSLANLIMRPHTIIFARPFALICMTYGGTYLTANTLDTATSTVKNKPATLVTSGTAKFVASSTANTGLGIYKDQVFARMFGPPGATPRPVPLPSYLLFAMRDAVTIFASFNLPIMLAPYLNNHLSDGFKKHISGQTLAQFAAPAAIQIISTPPHLLGLDLYNRPTCASSGSPTWAERWASVRSNWAISSCARVCRIVPAFGIGGVVNFKVRRQFMEKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVD8</accession>
    <name>G4MVD8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cell division control protein 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_12405</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CDC50/LEM3 family.</text>
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        <property type="protein sequence ID" value="EHA55764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003715523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVD8"/>
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    <dbReference type="FunCoup" id="G4MVD8">
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    </dbReference>
    <dbReference type="STRING" id="242507.G4MVD8"/>
    <dbReference type="GeneID" id="5050999"/>
    <dbReference type="KEGG" id="mgr:MGG_12405"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12405"/>
    <dbReference type="eggNOG" id="KOG2952">
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    <dbReference type="HOGENOM" id="CLU_025025_0_1_1"/>
    <dbReference type="InParanoid" id="G4MVD8"/>
    <dbReference type="OMA" id="TWNNDQP"/>
    <dbReference type="OrthoDB" id="340608at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005045">
        <property type="entry name" value="CDC50/LEM3_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926:SF0">
        <property type="entry name" value="CDC50, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03381">
        <property type="entry name" value="CDC50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015840">
        <property type="entry name" value="DUF284_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA55764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="437" mass="48366" checksum="22E0CB7862F636FD" modified="2011-12-14" version="1">MAGGGSIGTNGHADSINSHDDDSKKQDKKKSKRPANTAFRQQRLKAWQPILTPKTVLPLFFAIGVIFAPIGGGLLYASTTVRMISLDYTNCATQGGDNKFENMPSGLVKTQFGSSNQVNPPQWSRSTKKMKFSTNTDPNQNDTDVSVCTLQFTLPENMYPPVLMYYTLTNFYQNHRRYVSSFYDKQLKGDKVDINAVRSSPCTPLTVDSNNKAYYPCGLIANSMFNDTISEPVLLNSNSAEAKNGSEVYKMANNSNIAWPSDADLYGKFPSDMNIDDVVPPPNWRKQYGDKYTKETVPDLKTWQAFQVWMRTAGLPNFSKLYRRNDTAPMREGTYQVEIESHWPADAYRGTKSLLITTRTIIGGRNPFLGIAYIVVGGICIILGVIFTATHLIKPRKLGDHTYLSWNNAPAPKKGAAGAPPSTAQTSGRDYGGRAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWX8</accession>
    <name>G4MWX8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714077.1">
        <property type="nucleotide sequence ID" value="XM_003714029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWX8"/>
    <dbReference type="GeneID" id="12984582"/>
    <dbReference type="KEGG" id="mgr:MGG_15635"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15635"/>
    <dbReference type="HOGENOM" id="CLU_2574324_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWX8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="81" mass="8831" checksum="E61CFE484C309E28" modified="2011-12-14" version="1">MNSSRRLGCPVLEVQFYHARSGQSVLNTGAYFVDHLAGDRQPARPGFNYKSCNFSLPVLISVLEDGKEGRDGMLTATGRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXF6</accession>
    <name>G4MXF6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Mitochondrial chaperone BCS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_15496</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713293.1">
        <property type="nucleotide sequence ID" value="XM_003713245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXF6"/>
    <dbReference type="SMR" id="G4MXF6"/>
    <dbReference type="STRING" id="242507.G4MXF6"/>
    <dbReference type="GeneID" id="12986165"/>
    <dbReference type="KEGG" id="mgr:MGG_15496"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15496"/>
    <dbReference type="eggNOG" id="KOG0743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010189_4_3_1"/>
    <dbReference type="InParanoid" id="G4MXF6"/>
    <dbReference type="OMA" id="AKGMFER"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="BCS1 N-terminal" evidence="16">
        <location>
            <begin position="54"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="289"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="611"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="542"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="370"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="634"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA53486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="676" mass="74095" checksum="00C9C2E64C8F7DD5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYE1</accession>
    <name>G4MYE1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_08123</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="10"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715083.1">
        <property type="nucleotide sequence ID" value="XM_003715035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYE1"/>
    <dbReference type="SMR" id="G4MYE1"/>
    <dbReference type="STRING" id="242507.G4MYE1"/>
    <dbReference type="GeneID" id="2678405"/>
    <dbReference type="KEGG" id="mgr:MGG_08123"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08123"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_4_0_1"/>
    <dbReference type="InParanoid" id="G4MYE1"/>
    <dbReference type="OMA" id="GNETGNC"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000006">
        <property type="entry name" value="Beta-glucosidase H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000495">
        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF27">
        <property type="entry name" value="BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="11">
        <location>
            <begin position="405"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA55276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="844" mass="92090" checksum="ABFB55C862C5E098" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYX5</accession>
    <name>G4MYX5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713443.1">
        <property type="nucleotide sequence ID" value="XM_003713395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYX5"/>
    <dbReference type="STRING" id="242507.G4MYX5"/>
    <dbReference type="GeneID" id="5048667"/>
    <dbReference type="KEGG" id="mgr:MGG_14733"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14733"/>
    <dbReference type="eggNOG" id="ENOG502SD2N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_963132_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYX5"/>
    <dbReference type="OrthoDB" id="3439512at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="300" mass="33459" checksum="2EF660EB82688EA0" modified="2011-12-14" version="1">MHKRYSSSEDVLFANILSIYGQDAEALREITRLCAASPTQVEKTTPWEQHDIRVIYEFSCQIDDDNLFVIEVDAESFKFEIRDLPNQVPPILIHCLHRHWDLAITAACSSVQGVNKLCQTFGENLVKSLEIPSNTTGKPKLCYSEAYHSKPNKPIVTALRVLHIVSFVAPDKETQLRVTQVQNMATTLLPGRHAGWNRYTASLAKESPDQGIFSTWFTASLSSKKSDEMLKSNVTLNLGDEAEWTTKAFLRDGCVEPLLKHALAMVKGMDSIGVLCDNGHAVPSGEVITIPNSLAQIDFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYY9</accession>
    <name>G4MYY9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NTF2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA53650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003713409.1"/>
    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_11061"/>
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            <end position="519"/>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="8">EDC4-like protein pdc1 beta-propeller domain-containing protein</fullName>
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        <name evidence="9" type="ORF">MGG_01378</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
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    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat EDC4 family.</text>
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        <property type="nucleotide sequence ID" value="XM_003714267.1"/>
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    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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        <property type="entry name" value="EDC4-like"/>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598:SF5">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
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    </dbReference>
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        <property type="entry name" value="Beta-prop_EDC4L"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD40 repeat-like"/>
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    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
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            <end position="896"/>
        </location>
    </feature>
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        <location>
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    <feature type="region of interest" description="Disordered" evidence="7">
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    <feature type="region of interest" description="Disordered" evidence="7">
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    <feature type="region of interest" description="Disordered" evidence="7">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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    </feature>
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    </feature>
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        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
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            <end position="562"/>
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            <begin position="1"/>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA54508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1625" mass="176649" checksum="193B4858E909C3EB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZB1</accession>
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            <shortName evidence="9">U1C</shortName>
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        <name evidence="12" type="ORF">MGG_08209</name>
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            <taxon>Sordariomycetes</taxon>
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    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the U1 snRNP. The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. Interacts (via N-terminus) with TIA1 (via C-terminus); thereby promoting spliceosomal U1 snRNP recruitment to 5' splice sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the U1 small nuclear ribonucleoprotein C family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715191.1">
        <property type="nucleotide sequence ID" value="XM_003715143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZB1"/>
    <dbReference type="SMR" id="G4MZB1"/>
    <dbReference type="STRING" id="242507.G4MZB1"/>
    <dbReference type="GeneID" id="2678260"/>
    <dbReference type="KEGG" id="mgr:MGG_08209"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08209"/>
    <dbReference type="eggNOG" id="KOG3454">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079697_2_0_1"/>
    <dbReference type="InParanoid" id="G4MZB1"/>
    <dbReference type="OMA" id="QMRPPLM"/>
    <dbReference type="OrthoDB" id="76567at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000243">
        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030627">
        <property type="term" value="F:pre-mRNA 5'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
        <property type="term" value="P:mRNA 5'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000059">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03153">
        <property type="entry name" value="U1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017340">
        <property type="entry name" value="U1_snRNP-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148:SF1">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="11">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="72"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="120"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA55384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="218" mass="22067" checksum="92227702B905AF1E" modified="2011-12-14" version="1">MPKFFCDYCDVYLTHDSMSVRKAHNSGRNHLRNVIEYYQQIGHEKAQSVIDSITSSYAAEGQAHANPMLPHNQPGGSGFPPPFGFPGGVPPPFPGMPGAPPGGFPAGMPPPPGGARGMPNMPPFPPPIPGGPNPSGLPVPPPGALPPGMPPFPGMPFPPPGPAGPGGVPPPMMPPNFPAGFPGMPPPGPGGPGLPPPPFMPPGGMPPPGAMGGPDSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZH0</accession>
    <name>G4MZH0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714336.1">
        <property type="nucleotide sequence ID" value="XM_003714288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZH0"/>
    <dbReference type="STRING" id="242507.G4MZH0"/>
    <dbReference type="GeneID" id="2679135"/>
    <dbReference type="KEGG" id="mgr:MGG_01393"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01393"/>
    <dbReference type="eggNOG" id="KOG4279">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013324_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZH0"/>
    <dbReference type="OMA" id="HANAENC"/>
    <dbReference type="OrthoDB" id="5244984at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052751">
        <property type="entry name" value="Plant_MAPKKK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48011">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48011:SF86">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE 4-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="160"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="879" mass="96747" checksum="30F04F8CC6F23896" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZM8</accession>
    <name>G4MZM8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715199.1">
        <property type="nucleotide sequence ID" value="XM_003715151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZM8"/>
    <dbReference type="GeneID" id="12985587"/>
    <dbReference type="KEGG" id="mgr:MGG_15839"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15839"/>
    <dbReference type="HOGENOM" id="CLU_2850161_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZM8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="65" mass="7118" checksum="8EBBB59700EC1A1B" modified="2011-12-14" version="1">MNEFYVQLSMYAVECVYTLLSLGDDDQIRTAGRVGLPRAKVTSSQTLLFRAPKVVNAKPPKATAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1Q8</accession>
    <name>G4N1Q8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Low-temperature viability protein ltv1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTV1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711437.1">
        <property type="nucleotide sequence ID" value="XM_003711389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1Q8"/>
    <dbReference type="FunCoup" id="G4N1Q8">
        <property type="interactions" value="431"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N1Q8"/>
    <dbReference type="GeneID" id="2683444"/>
    <dbReference type="KEGG" id="mgr:MGG_07524"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07524"/>
    <dbReference type="eggNOG" id="KOG2637">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028555_1_0_1"/>
    <dbReference type="InParanoid" id="G4N1Q8"/>
    <dbReference type="OMA" id="TAQHFTL"/>
    <dbReference type="OrthoDB" id="5852896at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007307">
        <property type="entry name" value="Ltv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531">
        <property type="entry name" value="LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531:SF0">
        <property type="entry name" value="PROTEIN LTV1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04180">
        <property type="entry name" value="LTV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="206"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="45950" checksum="A046F82B31F958D2" modified="2011-12-14" version="1">MPKGKWIDKKTATHFTLVHRPQNDPLIHDESAPSMVLNPTQLPNATGKVKKLDDLASELGSDALSIRDNEGEAANYGVYFDDTEYDYMQHMRDLGSGTGEAVFIESTAGQQNKGKGKQKQSLEEALREMELQDKSSDLLDADILPSKDLTRATYQSQQDVPDMIAGFQPDMDPRLREVLEALEDEAYVDDDDDIFQQLSKDAKELNEHEFDDTYPDEYDDGWESDATAKPNKEFRDGDEAPQLVDTNAQPTEGPSQEWLEDFKKFKKDQSGEGRTRAGPGAGSEIQSSIWTTTTSGGRRKKRKGALTDKTGFSMTSSSLVRTEGLSALDARFDRIEEEYNADMESELGSVSGVSMASSVTGPMRHDFDGILDDFLGKQPNNKSAAGKRGKKHYKGGLAELDEIRKGLGPARISTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N240</accession>
    <name>G4N240_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RING-4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_07549</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711463.1">
        <property type="nucleotide sequence ID" value="XM_003711415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N240"/>
    <dbReference type="STRING" id="242507.G4N240"/>
    <dbReference type="GeneID" id="2683469"/>
    <dbReference type="KEGG" id="mgr:MGG_07549"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07549"/>
    <dbReference type="eggNOG" id="ENOG502S5JI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016574_3_0_1"/>
    <dbReference type="InParanoid" id="G4N240"/>
    <dbReference type="OMA" id="MIWQLST"/>
    <dbReference type="OrthoDB" id="4132249at2759"/>
    <dbReference type="PHI-base" id="PHI:5639"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF20">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="54"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="452"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="452"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="587" mass="64643" checksum="32CCBDB5A46FFE22" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N275</accession>
    <name>G4N275_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712294.1">
        <property type="nucleotide sequence ID" value="XM_003712246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N275"/>
    <dbReference type="SMR" id="G4N275"/>
    <dbReference type="STRING" id="242507.G4N275"/>
    <dbReference type="GeneID" id="2680503"/>
    <dbReference type="KEGG" id="mgr:MGG_09460"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09460"/>
    <dbReference type="eggNOG" id="ENOG502SR1T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082452_1_0_1"/>
    <dbReference type="InParanoid" id="G4N275"/>
    <dbReference type="OMA" id="TNANMAG"/>
    <dbReference type="OrthoDB" id="2422134at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF6">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181061" evidence="3">
        <location>
            <begin position="16"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="257" mass="25664" checksum="B937AE8E31424FCF" modified="2011-12-14" version="1">MQLSSLLVFVGAVAALDLPTNVRRDAPTKVERDLATISRVVTDVDSKIKDLTDSIKNFNGDPAALSKASSTLTSTLNQGASDVSAGTSITLNEAITLQAQVSGLQSDSNNLISALTDKKKAFEDASLCGVIYQQSGDLGTNAKSLIDAVVSKVPQDVQSLAQQVASGFSKTLMDTQAQFAPGNCTNKGTAAVPGGGSGSGSGTPAASGSGGVAGGASSSAPTGQPVTAGAATFAAPVGFVMALAAASFLLHCHYIPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2P6</accession>
    <name>G4N2P6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TBP-associated factor 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_04877</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712358.1">
        <property type="nucleotide sequence ID" value="XM_003712310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2P6"/>
    <dbReference type="SMR" id="G4N2P6"/>
    <dbReference type="FunCoup" id="G4N2P6">
        <property type="interactions" value="1034"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N2P6"/>
    <dbReference type="GeneID" id="2675628"/>
    <dbReference type="KEGG" id="mgr:MGG_04877"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04877"/>
    <dbReference type="eggNOG" id="KOG2549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021711_3_0_1"/>
    <dbReference type="InParanoid" id="G4N2P6"/>
    <dbReference type="OMA" id="YFVQFIA"/>
    <dbReference type="OrthoDB" id="361039at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22931">
        <property type="entry name" value="HFD_TAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000033">
        <property type="entry name" value="Transcription initiation factor TFIID complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="8">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00076308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA52551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="512" mass="54918" checksum="EC2D72146E22F48D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2V4</accession>
    <name>G4N2V4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713210.1">
        <property type="nucleotide sequence ID" value="XM_003713162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2V4"/>
    <dbReference type="GeneID" id="2683891"/>
    <dbReference type="KEGG" id="mgr:MGG_07964"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07964"/>
    <dbReference type="eggNOG" id="ENOG502SMFK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_1_2_1"/>
    <dbReference type="InParanoid" id="G4N2V4"/>
    <dbReference type="OMA" id="WWAREVS"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="PHI-base" id="PHI:10375"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="37295" checksum="10ACDB29963D8F1E" modified="2011-12-14" version="1">MNPIAPREYNDYDSAIGDIDRRSDRYGGTLRDTVLEYRVENGRTYHSLKEGSYWQPNDEPSQERLDLTHNLFVITFDNRMCMCPKNERARYVLDIGTGTGIWACDFADEHPEAHVVGVDLSPIQPHFVPTNCRFIIDDIESEWLFDDKFDLVFIRNMLGCFESWQTVFERAYGGLEAGGYLEVQDVALPIKCDDGTLPEDAVISYWCKLMLQAAEVAGRPIDITPRLADLMRQVGFEDVTVKKKRWPHAPWPRDRQMRLIGWWAREVSISDLDGMCMKLLMEKLGLTVEEVKEICAKVEEDCDNLRYHAYWDVYSIYGRKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2Z1</accession>
    <name>G4N2Z1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711557.1">
        <property type="nucleotide sequence ID" value="XM_003711509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2Z1"/>
    <dbReference type="SMR" id="G4N2Z1"/>
    <dbReference type="STRING" id="242507.G4N2Z1"/>
    <dbReference type="GeneID" id="2683552"/>
    <dbReference type="KEGG" id="mgr:MGG_07632"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07632"/>
    <dbReference type="eggNOG" id="ENOG502S5BH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030508_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2Z1"/>
    <dbReference type="OMA" id="FAMNATW"/>
    <dbReference type="OrthoDB" id="276515at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09083">
        <property type="entry name" value="EEP-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF36">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465687" evidence="1">
        <location>
            <begin position="20"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="309" mass="33210" checksum="4B50F55AC5661649" modified="2011-12-14" version="1">MLPTNLIALLLAAASAVDAGALIPRQAKPLALRVTSFNIRFDAEVSRREKQEKAWSDRKPVLVKTMADIAAKPATAGAPAIFGLQEVLSNQLSDIKKGMGAGWDHIGVAREDGKSKGEFSPIIYNTKDLKVVTSATKWLTETPDKPSKAAGAGSSRIVTLAVFEHVATKKRFLHANTHLDNVSPEARIAGIKVAVTQIQDMLKAQGGKLPVSLTGDFNSVAGGDAAKALADMNFVKDVHDVATKAQRSGEELTYTAFEQGAGRGRIDFVWIGPNADAPYTVQKYEVRANFVDNLFMSDHRAVVADITMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3Q2</accession>
    <name>G4N3Q2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711684.1">
        <property type="nucleotide sequence ID" value="XM_003711636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3Q2"/>
    <dbReference type="STRING" id="242507.G4N3Q2"/>
    <dbReference type="GeneID" id="12984185"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16707"/>
    <dbReference type="eggNOG" id="ENOG502T36W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_704137_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3Q2"/>
    <dbReference type="OrthoDB" id="5236058at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="481" mass="53352" checksum="10A78827C6B9BD5B" modified="2011-12-14" version="1">MSPQTNIKTSWLSRIKRYGGCLVLDCCRPSKAIKPYEGELWPNPENFHWSHKDRRFDCTPIEAGPVQTQPRPSSNMRVPSQLSALPVRVMIPTHPRLSQDLPPLPLPEPPVKIRSSIEPSQLFAERDGAASRSSSRLSSSTAGSKSSSRRSANEDERFERLNRKFLGASIIDEVLGIFDKASNMPYAVCGMAALAAWGYTLDKPRHITIMVPPYCRDTMTGWAKTVPQFETFASRPDVIGVQTSDGTIVRINITYPDAADGVWEDYFKTNRVQLHGIGAFAEVLRLSKLLNQTAVSYMDALELEDAELMGFISSDILWILWRIARGLAQGEENVKPLNPTEIPSVMDRTFWDSFVGTHPEASERFAAAGLHSRFQPSGDVRPSMHSVPQPSNPYWQPSPPTVETVDPMTGSSRTSMPTRTESASTVRLTPAEKLKQRFQQPRRQTATNGNGQPHTSRASCPASRNGSNSMAQASGPFRQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3R1</accession>
    <name>G4N3R1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GPR1/FUN34/YaaH-class plasma membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_05863</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711692.1">
        <property type="nucleotide sequence ID" value="XM_003711644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3R1"/>
    <dbReference type="SMR" id="G4N3R1"/>
    <dbReference type="GeneID" id="2684112"/>
    <dbReference type="KEGG" id="mgr:MGG_05863"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05863"/>
    <dbReference type="eggNOG" id="ENOG502S179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051062_4_0_1"/>
    <dbReference type="InParanoid" id="G4N3R1"/>
    <dbReference type="OMA" id="PPNKVKG"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF4">
        <property type="entry name" value="PROTEIN ALCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA51885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="35581" checksum="2F2606B558A6EEFA" modified="2011-12-14" version="1">MSNYTLTPKFYSNPGVPPKPPVEKYLPPQKQNEDPMQKLRSANTVNMSAELFEKLYLREARHTGLKDNHQQQRVQPRKFGDPTPIGYIGIVIGLTPLSCDLMGLLGAGGSAAGIDSYYFFGGLLQILAGLGEWFLGNTFPSIFFTTFGAFFLSFAATLTPSFAAFATYAPDGAPSSAGMDTQAFNAGFGWFTLWMGVLSVLFLVCSLRTNVVLVVLFGALVGTFTSLTGAYFMLASAASRNAAAAVAAVASRTSAATGTVVQASGAAGLAAARTASSFVLAGGVCAFVASMAVWWLLLAAMLDTMEFPITIPRGDLSRWIKPRQVGRDEPRVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3U9</accession>
    <name>G4N3U9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Chitin deacetylase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_05023</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
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        <property type="protein sequence ID" value="EHA52722.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_05023"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0005975">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
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        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF4">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465752" evidence="10">
        <location>
            <begin position="25"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="12">
        <location>
            <begin position="72"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="309"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="278"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="312"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA52722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="352" mass="38663" checksum="B5E81263E7A00D9C" modified="2011-12-14" version="1">MKQRITSLVCGLLGLLLLCDTVAAYDVRAGFGVNRRKGMVKRRVKGSTSNVERSFIGNVPYGEVITQCKKSKVVALTFDDGPSIYTEQVLNLLKQHNAKATFFLTANNGQWPMESEPWSGLVRRMMAEGHQIAHHSWSHQDMSVLDADTRKDEIVRAEEAFANVLGGRFPTYFRPPYGSCNADCLAQARRLGYHVVTWDVDSDDWRYQTEIERSERQVEDGVAAGGSIVLAHDIHYNSSTRLTQFMLELLARKGLRAVTVGECLEDPAEFWYREASASSGSGSSAATAPSKPKPKPKPGATSKLKASTDGRCGGDVTCSDKHWGSCCSRYGWCGSTADHCNAGCQSQFGQCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3Y0</accession>
    <name>G4N3Y0_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05881</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711709.1">
        <property type="nucleotide sequence ID" value="XM_003711661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3Y0"/>
    <dbReference type="GeneID" id="2684094"/>
    <dbReference type="KEGG" id="mgr:MGG_05881"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05881"/>
    <dbReference type="eggNOG" id="ENOG502RUEI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_7_2_1"/>
    <dbReference type="InParanoid" id="G4N3Y0"/>
    <dbReference type="OMA" id="NEYPPNA"/>
    <dbReference type="OrthoDB" id="4587016at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF64">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="44"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="651" mass="72983" checksum="F3950E829D64A17B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4N464</accession>
    <name>G4N464_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712591.1">
        <property type="nucleotide sequence ID" value="XM_003712543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N464"/>
    <dbReference type="SMR" id="G4N464"/>
    <dbReference type="GeneID" id="12985106"/>
    <dbReference type="KEGG" id="mgr:MGG_15125"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15125"/>
    <dbReference type="HOGENOM" id="CLU_2705296_0_0_1"/>
    <dbReference type="InParanoid" id="G4N464"/>
    <dbReference type="OrthoDB" id="10340826at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="73" mass="8545" checksum="F6588AC06E36ED49" modified="2011-12-14" version="1">MACRFERWQRAGHPSPHFPQTLFDFFVPDSIRLLGVFFCARSMVRDAHPNLVSISLVWVRRTEISHPVLRVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4A8</accession>
    <name>G4N4A8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc knuckle domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711783.1">
        <property type="nucleotide sequence ID" value="XM_003711735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4A8"/>
    <dbReference type="STRING" id="242507.G4N4A8"/>
    <dbReference type="GeneID" id="2684027"/>
    <dbReference type="KEGG" id="mgr:MGG_05948"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05948"/>
    <dbReference type="eggNOG" id="KOG4400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058879_2_0_1"/>
    <dbReference type="InParanoid" id="G4N4A8"/>
    <dbReference type="OMA" id="KGNPTCY"/>
    <dbReference type="OrthoDB" id="3863715at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.60.10:FF:000060">
        <property type="entry name" value="Zinc knuckle domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051714">
        <property type="entry name" value="Znf_CCHC_NABP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23002">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="199" mass="19776" checksum="871E2D352B707252" modified="2011-12-14" version="1">MDFGGAQSGGAGGRTCYTCGQPNHQARDCPNRGAAKCYNCGGEGHISRACPEEPKDQKICYRCSQPGHISRDCPSGGAGGGGGGGGGQSSGAECYKCGEVGHIARNCSKGGYGGGGGGGYSGGGGGYGGGYGGGAGGKTCYSCGGVGHMSRDCVNGSKCYNCGETGHFSRDCSKRSTTGEKMCYKCQQPGHVQAECPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4T8</accession>
    <name>G4N4T8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712710.1">
        <property type="nucleotide sequence ID" value="XM_003712662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4T8"/>
    <dbReference type="SMR" id="G4N4T8"/>
    <dbReference type="STRING" id="242507.G4N4T8"/>
    <dbReference type="GeneID" id="2675351"/>
    <dbReference type="KEGG" id="mgr:MGG_05172"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05172"/>
    <dbReference type="eggNOG" id="KOG1990">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022380_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4T8"/>
    <dbReference type="OrthoDB" id="1432093at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990431">
        <property type="term" value="P:priRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990432">
        <property type="term" value="P:siRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051181">
        <property type="entry name" value="CAF1_poly(A)_ribonucleases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092">
        <property type="entry name" value="POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092:SF22">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="426" mass="48997" checksum="786EDB7CCBF769F6" modified="2011-12-14" version="1">MASQSFWAGLETTGKIIDIDATNFWRLLPQVLEEIAGAEYVSFDLEMTGIRVKNGLSDRQDKFSVEEYYAAACEVAQTFQIIEFGSYGWTAYNFRLAPWYLGDNRTHLALAKFFDRRYTLSSNSFRFLRGNRGDDITSLALESGIMYLSRQEADEAYKYFIDPDKKVRNLIDLNKENLEANLFYDWVRSAITLWLQDPHKLEWLNIENPGGESLTNLQRRLVYQILESEFSHDCLRAVPKCKNDFMQITQKGVNAAEETRMIERKAAIREQTGFRFVFEALVGGDFADDIDIGLLLTPEEYHIKGSAADLRAKLLAIEAKAKENSRVIVGHNSLFDLCFIYNSFIGTLPTSLQQFKIDIRAMFPRYVDTKYMATQDAKNIEFDQNLEELYCTVQSQKLPLFHPKAPMCRSSHQAGYDSSYFLVLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4U3</accession>
    <name>G4N4U3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711862.1">
        <property type="nucleotide sequence ID" value="XM_003711814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4U3"/>
    <dbReference type="GeneID" id="12984232"/>
    <dbReference type="KEGG" id="mgr:MGG_16737"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16737"/>
    <dbReference type="HOGENOM" id="CLU_1447961_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4U3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465741" evidence="1">
        <location>
            <begin position="19"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="187" mass="20834" checksum="6F86CCC7478CBDAE" modified="2011-12-14" version="1">MLPSFFILSSLFVLPGLGASVSNTKTNSNAATQNANGLRTHTFYGSSVRLPFGTAADPELIKEYGGFTIELAERLKSEGRDRVGLGAHSSNVLIGNRKYFPRENVYVYEFDSGNDRLFRAYDAHLTNIRTDYGRITQPSEQVNPLNLNHNAVEMAKTFQIPIEEILGAWYIGPERGGLWAVRFQKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4Z3</accession>
    <name>G4N4Z3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc transporter YKE4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711912.1">
        <property type="nucleotide sequence ID" value="XM_003711864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4Z3"/>
    <dbReference type="FunCoup" id="G4N4Z3">
        <property type="interactions" value="161"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N4Z3"/>
    <dbReference type="GeneID" id="2683915"/>
    <dbReference type="KEGG" id="mgr:MGG_06060"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06060"/>
    <dbReference type="eggNOG" id="KOG2693">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015114_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4Z3"/>
    <dbReference type="OMA" id="IWLHSIG"/>
    <dbReference type="OrthoDB" id="200954at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950">
        <property type="entry name" value="ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950:SF16">
        <property type="entry name" value="ZINC TRANSPORTER ZIP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465812" evidence="7">
        <location>
            <begin position="24"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="413" mass="42891" checksum="EEAD7229693A2DDC" modified="2011-12-14" version="1">MPPMRFNHFLALILGVGVACTLAGTAPGITVSMSLEDLDEKLQQCDVVKEMSAEKAAHFAQTSASSMSALLDMLFPGGPAVNAILATFYISGPPTFLLALCPKNIDPSSLSTMVAFAVGGLMGDTLFHLLPEIFLGEDEPDQARFVLVEPNRNLLLGVGILVGFMTFVAMDKGLRIATGGAGGHDHSHGHSHGAHAHDATVEVVSATSVDTGKGARSRKSAGPDKAAANGSKEVATVKEPTQQVNSSGLLNLIADFTHNITDGLAMSASFYASPTIGATTALAVALHECPHQVGDFALLIQSGFSKWSAIGLQFVTALGALLGTLIGIAVQEFGGSGGEPVLMGAGLWGTSLTWGDMLLPFTAGTFLYVGTVAAVPELLETEAGDKVREVKKTFVQFVAVALGAGIMLYISWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5R2</accession>
    <name>G4N5R2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dual specificity phosphatase catalytic domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05298</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712859.1">
        <property type="nucleotide sequence ID" value="XM_003712811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5R2"/>
    <dbReference type="SMR" id="G4N5R2"/>
    <dbReference type="STRING" id="242507.G4N5R2"/>
    <dbReference type="GeneID" id="2675761"/>
    <dbReference type="KEGG" id="mgr:MGG_05298"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05298"/>
    <dbReference type="eggNOG" id="KOG2386">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013931_1_1_1"/>
    <dbReference type="InParanoid" id="G4N5R2"/>
    <dbReference type="OMA" id="PGIRHGH"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14502">
        <property type="entry name" value="RNA_5'-triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000090">
        <property type="entry name" value="Dual specificity phosphatase catalytic domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF25">
        <property type="entry name" value="DUAL SPECIFICITY PHOSPHATASE CATALYTIC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03540)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="3">
        <location>
            <begin position="578"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="669" mass="74332" checksum="F9C8E3198410B4C4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6C9</accession>
    <name>G4N6C9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Microbial-type PARG catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716970.1">
        <property type="nucleotide sequence ID" value="XM_003716922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6C9"/>
    <dbReference type="SMR" id="G4N6C9"/>
    <dbReference type="STRING" id="242507.G4N6C9"/>
    <dbReference type="GeneID" id="2684722"/>
    <dbReference type="KEGG" id="mgr:MGG_06567"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06567"/>
    <dbReference type="eggNOG" id="ENOG502S1YN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024412_1_0_1"/>
    <dbReference type="InParanoid" id="G4N6C9"/>
    <dbReference type="OMA" id="MPWNAQL"/>
    <dbReference type="OrthoDB" id="2440523at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012664">
        <property type="entry name" value="CHP02452"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019261">
        <property type="entry name" value="PARG_cat_microbial"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02452">
        <property type="entry name" value="TIGR02452 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596">
        <property type="entry name" value="DUF2263 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35596:SF2">
        <property type="entry name" value="MICROBIAL-TYPE PARG CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10021">
        <property type="entry name" value="PARG_cat_microb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Microbial-type PARG catalytic" evidence="1">
        <location>
            <begin position="112"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="381" mass="42403" checksum="765C34C17791AA95" modified="2011-12-14" version="1">MILLIIYKGRSTLPATISFPPHFSIHLLQSPYLPTRIRLQSRKFCQLSSFVLISGIAFIMSSSRAQAKSTSTSSRTFKPKASEVAHETKKSIIPRIQTHYADKWGTWSYYFQDPLAQVSVEPDPHANPTNFSVYVDDPVNYALHWLSHSEPGAPVAFICAANEKRPGGDWVTGVVGYEERLCRRSTLSATLSTAGPGSHTKDAYPISSVGGIFSPQVVIFRSETDRSEPLMEEQWQDIPVCSVPPVRWPKVNMTSGVLQYSFADERDLMREKITGALAICYSRGITNIVVGDFGLGNGHRNPPSEVAQLWWEVTSSGPLQGRIHNIAFIFEDARQSTRSLILEDLAKKHRKNGGIIPLALANALREPPVSDYDEFLNMFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6E5</accession>
    <name>G4N6E5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716134.1">
        <property type="nucleotide sequence ID" value="XM_003716086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6E5"/>
    <dbReference type="STRING" id="242507.G4N6E5"/>
    <dbReference type="GeneID" id="5051626"/>
    <dbReference type="KEGG" id="mgr:MGG_13465"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13465"/>
    <dbReference type="eggNOG" id="ENOG502RJ6T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_774273_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6E5"/>
    <dbReference type="OMA" id="CGHRARE"/>
    <dbReference type="OrthoDB" id="5236983at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SprT-like" evidence="1">
        <location>
            <begin position="198"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="400" mass="43897" checksum="410858B3160E799A" modified="2011-12-14" version="1">MANWLGCRGVGAHQNRAEPVPNPTNFSAFPEDEMHEVSTWYVDACDRGMGLDEPFLGRRCTEEAASLGIPGQSVWTPVPGEHHVFFVRAPTPSPPRQVYARTPTAVPLERTSSGRSITAASISSWALEHADDTDLNLVSDAEAARWVGEYTADFFYRYPDSTYERILRTLITPRPSSPLTINGAHDPDFELDDAVLASIFSATNEMFFAGRLTNRVSWDWSGTSISTGCKYETDIIGTTAMRKRPAGGYEALIVLSSPILRGTNGGLFSRRLLISTFIHELIHCYLFVCCGHRARECGGHTAGFIKIASVLDDWAGHGVLHLREMEADLERFRTTASAVQTAYGMSNHSSPSHYGPCSGHGLSSRRSLQGWDCSPTGGGPRGWDDCGQGSGLLHDDWLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6E8</accession>
    <name>G4N6E8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Pheromone processing endoprotease KexB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_15291</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S8 family. Furin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716137.1">
        <property type="nucleotide sequence ID" value="XM_003716089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6E8"/>
    <dbReference type="SMR" id="G4N6E8"/>
    <dbReference type="FunCoup" id="G4N6E8">
        <property type="interactions" value="156"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N6E8"/>
    <dbReference type="MEROPS" id="S08.070"/>
    <dbReference type="GeneID" id="12984330"/>
    <dbReference type="KEGG" id="mgr:MGG_15291"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15291"/>
    <dbReference type="eggNOG" id="KOG3525">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002976_2_1_1"/>
    <dbReference type="InParanoid" id="G4N6E8"/>
    <dbReference type="OMA" id="PWMHVKH"/>
    <dbReference type="OrthoDB" id="300641at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007323">
        <property type="term" value="P:peptide pheromone maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000026">
        <property type="entry name" value="proprotein convertase subtilisin/kexin type 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000005">
        <property type="entry name" value="Proprotein convertase subtilisin/kexin type 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884:SF14">
        <property type="entry name" value="NEUROENDOCRINE CONVERTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 14 19" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466097" evidence="17">
        <location>
            <begin position="19"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="725"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="18">
        <location>
            <begin position="480"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="624"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="775"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="682"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="813"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13 14">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13 14">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13 14">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA49818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="852" mass="92889" checksum="43646A4E30721ABC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7B3</accession>
    <name>G4N7B3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="15">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="15">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ALA1</name>
        <name evidence="18" type="ORF">MGG_03607</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14 15">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="15"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716291.1">
        <property type="nucleotide sequence ID" value="XM_003716243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7B3"/>
    <dbReference type="SMR" id="G4N7B3"/>
    <dbReference type="FunCoup" id="G4N7B3">
        <property type="interactions" value="994"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7B3"/>
    <dbReference type="GeneID" id="2676649"/>
    <dbReference type="KEGG" id="mgr:MGG_03607"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03607"/>
    <dbReference type="eggNOG" id="KOG0188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004485_5_0_1"/>
    <dbReference type="InParanoid" id="G4N7B3"/>
    <dbReference type="OMA" id="NKKDNFW"/>
    <dbReference type="OrthoDB" id="2423964at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070143">
        <property type="term" value="P:mitochondrial alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.130:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.40:FF:000003">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000011">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059090">
        <property type="entry name" value="ALA1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26023">
        <property type="entry name" value="ALA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 15 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 15" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="7 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="17">
        <location>
            <begin position="130"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1044"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="723"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="727"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="842"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="846"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA49972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1084" mass="120938" checksum="EE52814BC815EDE3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7B4</accession>
    <name>G4N7B4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03606</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716292.1">
        <property type="nucleotide sequence ID" value="XM_003716244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7B4"/>
    <dbReference type="FunCoup" id="G4N7B4">
        <property type="interactions" value="24"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7B4"/>
    <dbReference type="GeneID" id="2676648"/>
    <dbReference type="KEGG" id="mgr:MGG_03606"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03606"/>
    <dbReference type="eggNOG" id="ENOG502QRKD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028484_1_0_1"/>
    <dbReference type="InParanoid" id="G4N7B4"/>
    <dbReference type="OMA" id="LPFAPNM"/>
    <dbReference type="OrthoDB" id="17415at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12710:FF:000002">
        <property type="entry name" value="Protein arginine methyltransferase NDUFAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="25"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="516" mass="60369" checksum="E300A0ACD0397358" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7S7</accession>
    <name>G4N7S7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Zinc transporter SLC39A9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_06374</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717200.1">
        <property type="nucleotide sequence ID" value="XM_003717152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7S7"/>
    <dbReference type="STRING" id="242507.G4N7S7"/>
    <dbReference type="GeneID" id="2684529"/>
    <dbReference type="KEGG" id="mgr:MGG_06374"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06374"/>
    <dbReference type="eggNOG" id="KOG3907">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028824_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7S7"/>
    <dbReference type="OMA" id="DDFPSIC"/>
    <dbReference type="OrthoDB" id="19859at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045891">
        <property type="entry name" value="ZIP9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133:SF0">
        <property type="entry name" value="ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466218" description="Zinc transporter SLC39A9" evidence="9">
        <location>
            <begin position="18"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="118"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="135"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA50881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="44995" checksum="7A3EB857A16A9B22" modified="2011-12-14" version="1">MGGLLLLLVLCVVMALASFLAGALPLSLTLSQSQLRLISSIGVGILVGTSLIVIIPEGIEAIASTSLPAHTGSHTRRFDIHGKAVSPRWEAAHMVEKRSLIDLETGDSPRMPFLRIGVPMPPKPNELAHQGGESLPKRDGLPIVVTREDTPKDATKPSGEDPKTSKDSQQAQNERVLPTFFIGFSLTSGFILMFLIDRIPRQAMDQFQPTPTTRHISLDNLASSSGAGEEESQGFLGSLAPTPKHSRSLATTTGLVIHAAADGIAMGASATTSNMKLGLIIFAAIMIHKAPAAFGLTSVLLKQGLSKRAARGHLIVFSLAAPAGAIGTYLLVSILGGQNVEGESGQWWTGMLLLFSAGTFLYVAMHAMQEENTAAYEHHGGMNGYADNGGAPHRKHIRPQLRDTLATVFGMLLPLLTQFGHHH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2021-06-02" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7X0</accession>
    <name>MST11_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitogen-activated protein kinase kinae kinase MST11</fullName>
            <shortName evidence="8">MAPKKK MST11</shortName>
            <ecNumber evidence="10">2.7.11.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">MEKK MST11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MST11</name>
        <name type="ORF">MGG_14847</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2005" name="Plant Cell" volume="17" first="1317" last="1329">
            <title>A mitogen-activated protein kinase cascade regulating infection-related morphogenesis in Magnaporthe grisea.</title>
            <authorList>
                <person name="Zhao X."/>
                <person name="Kim Y."/>
                <person name="Park G."/>
                <person name="Xu J.R."/>
            </authorList>
            <dbReference type="PubMed" id="15749760"/>
            <dbReference type="DOI" id="10.1105/tpc.104.029116"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <scope>DOMAIN</scope>
        <scope>INTERACTION WITH MST50</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2011" name="PLoS Pathog." volume="7" first="e1001261" last="e1001261">
            <title>Multiple plant surface signals are sensed by different mechanisms in the rice blast fungus for appressorium formation.</title>
            <authorList>
                <person name="Liu W."/>
                <person name="Zhou X."/>
                <person name="Li G."/>
                <person name="Li L."/>
                <person name="Kong L."/>
                <person name="Wang C."/>
                <person name="Zhang H."/>
                <person name="Xu J.R."/>
            </authorList>
            <dbReference type="PubMed" id="21283781"/>
            <dbReference type="DOI" id="10.1371/journal.ppat.1001261"/>
        </citation>
        <scope>FUNCTION</scope>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2013" name="Gene Expr. Patterns" volume="13" first="133" last="141">
            <title>Complexity of roles and regulation of the PMK1-MAPK pathway in mycelium development, conidiation and appressorium formation in Magnaporthe oryzae.</title>
            <authorList>
                <person name="Jin Q."/>
                <person name="Li C."/>
                <person name="Li Y."/>
                <person name="Shang J."/>
                <person name="Li D."/>
                <person name="Chen B."/>
                <person name="Dong H."/>
            </authorList>
            <dbReference type="PubMed" id="23454094"/>
            <dbReference type="DOI" id="10.1016/j.gep.2013.02.003"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="5 6 7 10">Mitogen-activated protein kinase kinase kinase; part of the MST11-MST7-PMK1 MAP kinase (MAPK) cascade that is essential for appressorium formation, penetration and invasive growth (PubMed:15749760, PubMed:23454094). The MST11-MST7-PMK1 MAP kinase cascade transduces signals from the cell surface sensors MDB2 and SHO1 that recognize various surface signals such as surface hydrophobicity, cutin monomers, and rice leaf waxes (PubMed:21283781). MST11 acts as the upstream MAPKKK that directly phosphorylates MAPKK MST7 (Probable). MST11 but not MST7 may also be involved in the OSM1 MAPK pathway in response to osmotic stresses (PubMed:15749760).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Interacts with the adapter protein MST50.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The N-terminal sterile alpha motif (SAM) domain, but not the Ras-associating (RA) domain, is essential for the function.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="5 7">Produces much less aerial hyphae and conidia and shows weakened cell walls and higher sensitivity to cell wall-degrading enzymes (PubMed:15749760). Impairs the formation of appressoria and the ability to infect rice plants (PubMed:15749760, PubMed:23454094).</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="10"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717243.1">
        <property type="nucleotide sequence ID" value="XM_003717195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7X0"/>
    <dbReference type="SMR" id="G4N7X0"/>
    <dbReference type="FunCoup" id="G4N7X0">
        <property type="interactions" value="147"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7X0"/>
    <dbReference type="EnsemblFungi" id="MGG_14847T0">
        <property type="protein sequence ID" value="MGG_14847T0"/>
        <property type="gene ID" value="MGG_14847"/>
    </dbReference>
    <dbReference type="GeneID" id="5048863"/>
    <dbReference type="KEGG" id="mgr:MGG_14847"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14847"/>
    <dbReference type="eggNOG" id="KOG0198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003051_0_1_1"/>
    <dbReference type="InParanoid" id="G4N7X0"/>
    <dbReference type="OMA" id="FIGAHPF"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="PHI-base" id="PHI:2119"/>
    <dbReference type="PHI-base" id="PHI:418"/>
    <dbReference type="PHI-base" id="PHI:8262"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09534">
        <property type="entry name" value="SAM_Ste11_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000075">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000334">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000214">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029458">
        <property type="entry name" value="Ras-bd_By2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14847">
        <property type="entry name" value="Ras_bdg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01304">
        <property type="entry name" value="Ras_bdg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <feature type="chain" id="PRO_0000453097" description="Mitogen-activated protein kinase kinae kinase MST11">
        <location>
            <begin position="1"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="3">
        <location>
            <begin position="65"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="2">
        <location>
            <begin position="263"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="641"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="134"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="183"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="647"/>
            <end position="655"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="670"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="15749760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="6">
        <source>
            <dbReference type="PubMed" id="21283781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="7">
        <source>
            <dbReference type="PubMed" id="23454094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="8">
        <source>
            <dbReference type="PubMed" id="15749760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="9"/>
    <evidence type="ECO:0000305" key="10">
        <source>
            <dbReference type="PubMed" id="15749760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA50924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="915" mass="101021" checksum="D5D67F423E255DB2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8A2</accession>
    <name>G4N8A2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mtf2-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA50149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003716420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8A2"/>
    <dbReference type="STRING" id="242507.G4N8A2"/>
    <dbReference type="GeneID" id="2676874"/>
    <dbReference type="KEGG" id="mgr:MGG_03458"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03458"/>
    <dbReference type="eggNOG" id="ENOG502S7AT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028481_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8A2"/>
    <dbReference type="OMA" id="GPLYPAY"/>
    <dbReference type="OrthoDB" id="2444174at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Mtf2-like_C"/>
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    <dbReference type="InterPro" id="IPR040009">
        <property type="entry name" value="Mtf2/C5D6.12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39468">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39468:SF1">
        <property type="entry name" value="MTF2-LIKE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19189">
        <property type="entry name" value="Mtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="334"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="551" mass="61324" checksum="857DDF88F68B72DB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8J6</accession>
    <name>G4N8J6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03426</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716509.1">
        <property type="nucleotide sequence ID" value="XM_003716461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8J6"/>
    <dbReference type="SMR" id="G4N8J6"/>
    <dbReference type="STRING" id="242507.G4N8J6"/>
    <dbReference type="GeneID" id="2676524"/>
    <dbReference type="KEGG" id="mgr:MGG_03426"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03426"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="InParanoid" id="G4N8J6"/>
    <dbReference type="OMA" id="VYLCCHH"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF133">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
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        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="251" mass="25828" checksum="34925EBC4E4A0A89" modified="2011-12-14" version="1">MARFTDKIALVTSAASGSGAAIVRRLASEGATVIAADKTGQEALAAELGPSVIARTLDAGSEASIAELDAYIRSAHGRLDILVNNTGMGGPRCPLLEVTPAAAAEVFNYNILGAYLLLQLGLRYMTAQPQGGAVVLTASIAGLVGTPHSSPYSVSKGAVVAMCKTAAVEYAKDRVRVNCVAPGPTAVPMVQRLGESANDRLRQRIPQGRLAEPSEVAAVVAFLADDRDAGHVTAPLPYYSSTNVVALVDTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8L5</accession>
    <name>G4N8L5_PYRO7</name>
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        <recommendedName>
            <fullName evidence="3">Methyltransferase</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17096</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716528.1">
        <property type="nucleotide sequence ID" value="XM_003716480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8L5"/>
    <dbReference type="GeneID" id="12984488"/>
    <dbReference type="KEGG" id="mgr:MGG_17096"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17096"/>
    <dbReference type="HOGENOM" id="CLU_2606496_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8L5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="8915" checksum="0E7C08E21A4D5C35" modified="2011-12-14" version="1">MSPTNLQIGDHTSHDLGFTQAVLQFAPQNLTMALLHPEIMATVFPYIRAIQGDGTILFHEQHMGRVEEPAWTPFPWCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8M4</accession>
    <name>G4N8M4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone chaperone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716537.1">
        <property type="nucleotide sequence ID" value="XM_003716489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8M4"/>
    <dbReference type="GeneID" id="2676950"/>
    <dbReference type="KEGG" id="mgr:MGG_03403"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03403"/>
    <dbReference type="HOGENOM" id="CLU_139257_2_0_1"/>
    <dbReference type="InParanoid" id="G4N8M4"/>
    <dbReference type="OMA" id="MDNDYKS"/>
    <dbReference type="OrthoDB" id="4357148at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="9853" checksum="AF95E59615720500" modified="2011-12-14" version="1">MSPSNDSVPSGNVSDNSYMSKASDPVPVVGDAQEVESSINPGQEDSDATLERDDKDAIDTSNIIDEPRAKPGKGALAEKDYSDEELVQEGDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9L9</accession>
    <name>G4N9L9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Alpha-galactosidase</fullName>
            <ecNumber evidence="4 8">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_13626</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="4 8"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717526.1">
        <property type="nucleotide sequence ID" value="XM_003717478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9L9"/>
    <dbReference type="SMR" id="G4N9L9"/>
    <dbReference type="STRING" id="242507.G4N9L9"/>
    <dbReference type="CAZy" id="CBM1">
        <property type="family name" value="Carbohydrate-Binding Module Family 1"/>
    </dbReference>
    <dbReference type="CAZy" id="GH27">
        <property type="family name" value="Glycoside Hydrolase Family 27"/>
    </dbReference>
    <dbReference type="GeneID" id="2681012"/>
    <dbReference type="KEGG" id="mgr:MGG_13626"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13626"/>
    <dbReference type="eggNOG" id="KOG2366">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013093_2_2_1"/>
    <dbReference type="InParanoid" id="G4N9L9"/>
    <dbReference type="OMA" id="WHDPDMI"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000197">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF75">
        <property type="entry name" value="ALPHA-GALACTOSIDASE MEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466203" description="Alpha-galactosidase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="10">
        <location>
            <begin position="335"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA51207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="427" mass="46329" checksum="64489DDF4752D0BA" modified="2011-12-14" version="1">MVAKTVTFASTAILALANASPMEKRLENGLGRTPALGWNSWNVAQCNAATEAFALDTANRFISMGLKDLGYTYVNIDDCWSTMQRNSSGYLVADPKKWPRGIKPVVDEIHAKGLKFGLYGSAGTKTCAGYPASQGYEGKDAQLLAEWGVDYWKHDNCYTPCRQGLPQTCPENQVAGNTRTWYGTMRDAVLATKKPIFFSLCNWGRDRVWEWGKDYGNSWRMSIDIWNDWASVIRIGSAAAGIAQYSAPGGFNDLDMMQISNGALNPAQERTHMGIWAIAKSPIILGMDLSKISASSLAIIKNKGLIAINQDKLGKAATYFQPPGKPAPVSGQLYPYWAGPLSDGVVVGLTNAMGTGRQTLAVDFKDVPGLGAGTWSWTEMYSGRTGSGTGVSFDLERYDMAVFKVVKPKSAEMVNQADSALWSTGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9M8</accession>
    <name>G4N9M8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_09976</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    <dbReference type="PANTHER" id="PTHR23502">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
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    </feature>
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        <location>
            <begin position="1"/>
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    </feature>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="433" mass="47699" checksum="EF537596C1FFE0FC" modified="2011-12-14" version="1">MSTSLSSHLFARALQGLGAGAVEALIPLVVQDMFFLHQRNTWMSVVVSSQGLLIISVGIATPYIAANYSWRWIYWITSGFGVFAWVLLLFFMPETRFTRSKKALVGEAIYPLEEGEDRPQIDHLNYAPRTIWTEIGVFNCGFEWREAGISMLNTLRTTLFPVVIWTTLMNSAFIIAAQATQQISAFALLAQGWRYEHTGLSFAPFVVAALFVYVFAGPVADKLSLATTRWQARHMGSRRSGGSGSDSEDCVLETVPAENLREAEHTLPNFVLPFLAGIAGAFLFGASAQQNLHWAITLTGSFLIIFGYLTTLTLANVFAIESYPMWAGPVLVNVSSMRIMIAFFMASQATSWVQTKGAMATFAIYGETLIVVSLGIVVLFFFGKKIRSWTAGKVKLSVVSEDRDQQDGGNRGSKGLSSGVRGLRRKSQGFEMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003717551.1"/>
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    <dbReference type="GeneID" id="2680752"/>
    <dbReference type="KEGG" id="mgr:MGG_09753"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09753"/>
    <dbReference type="HOGENOM" id="CLU_1603066_0_0_1"/>
    <dbReference type="InParanoid" id="G4NA34"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
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        </location>
    </feature>
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        </location>
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        <location>
            <begin position="118"/>
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    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
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            <begin position="71"/>
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    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
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            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="166" mass="14530" checksum="CACBF3E99D55A1E7" modified="2011-12-14" version="1">MPDVKSLALFILLLPFYGVMALPIDPASGSLDAVDHGVPAVARDVQAAAATADTAQIETANEAEKRKKKGGGGGGGGGGGGGGGGGAGGFLEIGKDGLKLGGSGFGFGGGGGGGGRNGGGGGGGLGGSGGGGGGGGLPGLPAGLPGLGALFGSAGAGAGAGAGAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAD5</accession>
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    <protein>
        <submittedName>
            <fullName evidence="8">Katanin p60 ATPase-containing subunit</fullName>
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    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03191</name>
    </gene>
    <organism evidence="8 9">
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        <lineage>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716799.1">
        <property type="nucleotide sequence ID" value="XM_003716751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAD5"/>
    <dbReference type="SMR" id="G4NAD5"/>
    <dbReference type="STRING" id="242507.G4NAD5"/>
    <dbReference type="GeneID" id="2676998"/>
    <dbReference type="KEGG" id="mgr:MGG_03191"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03191"/>
    <dbReference type="eggNOG" id="KOG0737">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004223_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAD5"/>
    <dbReference type="OMA" id="IFMHATD"/>
    <dbReference type="OrthoDB" id="39734at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051701">
        <property type="entry name" value="Mito_OM_Translocase_MSP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644:SF56">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="762"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="66"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA50480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1040" mass="115241" checksum="C9CB8643FA335A1E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAF7</accession>
    <name>G4NAF7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_09736</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717614.1">
        <property type="nucleotide sequence ID" value="XM_003717566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAF7"/>
    <dbReference type="GeneID" id="2680690"/>
    <dbReference type="KEGG" id="mgr:MGG_09736"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09736"/>
    <dbReference type="eggNOG" id="ENOG502S7YR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088618_1_1_1"/>
    <dbReference type="InParanoid" id="G4NAF7"/>
    <dbReference type="OMA" id="SFDIYLV"/>
    <dbReference type="OrthoDB" id="5316007at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052479">
        <property type="entry name" value="GPI-anchor_Adhesion_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35185">
        <property type="entry name" value="SERINE/THREONINE-RICH PROTEIN ADG2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35185:SF1">
        <property type="entry name" value="UPF0619 GPI-ANCHORED MEMBRANE PROTEIN C1322.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466255" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="112"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA51295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="210" mass="20587" checksum="C59045F50786C150" modified="2011-12-14" version="1">MVSSLAILALASSALALKVTSPDSNTNWSSGEKHTIKWETVSSDQPTFNIYLSNKVTYPPTDVLLASDVKASDGSFEVDSGKLPAGNDFTINLTNGTKTEQIYAQSNQFNVTGGSSSSSSSSSSSTTKTASGSSTAVSSTGADSSATASPTASGSGSTTKPTSAGASGASSTASGTGSAASATSTKASNSANGKMVASWIGAAALAVLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAP7</accession>
    <name>G4NAP7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_15353</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NodC/HAS family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716009.1">
        <property type="nucleotide sequence ID" value="XM_003715961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAP7"/>
    <dbReference type="STRING" id="242507.G4NAP7"/>
    <dbReference type="GeneID" id="12986475"/>
    <dbReference type="KEGG" id="mgr:MGG_15353"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15353"/>
    <dbReference type="eggNOG" id="KOG2571">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024200_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAP7"/>
    <dbReference type="OMA" id="KSATYVW"/>
    <dbReference type="OrthoDB" id="9876900at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050501">
        <property type="term" value="F:hyaluronan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085029">
        <property type="term" value="P:extracellular matrix assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030213">
        <property type="term" value="P:hyaluronan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22913">
        <property type="entry name" value="HYALURONAN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22913:SF12">
        <property type="entry name" value="MANNURONAN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="7">
        <location>
            <begin position="258"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA49690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="589" mass="66645" checksum="D035EB1600B74815" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAR5</accession>
    <name>G4NAR5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 60</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716826.1">
        <property type="nucleotide sequence ID" value="XM_003716778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAR5"/>
    <dbReference type="SMR" id="G4NAR5"/>
    <dbReference type="FunCoup" id="G4NAR5">
        <property type="interactions" value="1396"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAR5"/>
    <dbReference type="GeneID" id="2676963"/>
    <dbReference type="KEGG" id="mgr:MGG_03165"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03165"/>
    <dbReference type="eggNOG" id="KOG0356">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016503_3_0_1"/>
    <dbReference type="InParanoid" id="G4NAR5"/>
    <dbReference type="OMA" id="TDTDKME"/>
    <dbReference type="OrthoDB" id="1733909at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006458">
        <property type="term" value="P:'de novo' protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045041">
        <property type="term" value="P:protein import into mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="589" mass="61850" checksum="F21E06B3C0EB3A84" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC30</accession>
    <name>G4NC30_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_00450</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718617.1">
        <property type="nucleotide sequence ID" value="XM_003718569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC30"/>
    <dbReference type="SMR" id="G4NC30"/>
    <dbReference type="FunCoup" id="G4NC30">
        <property type="interactions" value="234"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NC30"/>
    <dbReference type="GeneID" id="2674138"/>
    <dbReference type="KEGG" id="mgr:MGG_00450"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00450"/>
    <dbReference type="eggNOG" id="ENOG502QQI5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018247_2_0_1"/>
    <dbReference type="InParanoid" id="G4NC30"/>
    <dbReference type="OMA" id="MRYAGEM"/>
    <dbReference type="OrthoDB" id="184182at2759"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.8.10:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.449.10:FF:000002">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase [ATP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA49033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="601" mass="66621" checksum="51BDD7FE5BA11A51" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCL4</accession>
    <name>G4NCL4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718692.1">
        <property type="nucleotide sequence ID" value="XM_003718644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCL4"/>
    <dbReference type="SMR" id="G4NCL4"/>
    <dbReference type="STRING" id="242507.G4NCL4"/>
    <dbReference type="GeneID" id="2674416"/>
    <dbReference type="KEGG" id="mgr:MGG_00384"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00384"/>
    <dbReference type="eggNOG" id="ENOG502SDRZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008005_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCL4"/>
    <dbReference type="OMA" id="LNVMEGN"/>
    <dbReference type="OrthoDB" id="3438840at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="351"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="642"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="437"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="681"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="701"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="759"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="779"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="935" mass="100748" checksum="454C1CDA785FDF31" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND92</accession>
    <name>G4ND92_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bulb-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718814.1">
        <property type="nucleotide sequence ID" value="XM_003718766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND92"/>
    <dbReference type="GeneID" id="12985005"/>
    <dbReference type="KEGG" id="mgr:MGG_17484"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17484"/>
    <dbReference type="HOGENOM" id="CLU_2979583_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND92"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bulb-type lectin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="58" mass="6469" checksum="F81CAEFC3A6F4F4C" modified="2011-12-14" version="1">MWSSGWAIWVAGRRAIPAGDGSNTNETYSTMGRLLVIMHRIKNGAKCRPKVDRHVQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDE9</accession>
    <name>G4NDE9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Copper-transporting ATPase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_00930</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718022.1">
        <property type="nucleotide sequence ID" value="XM_003717974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDE9"/>
    <dbReference type="SMR" id="G4NDE9"/>
    <dbReference type="STRING" id="242507.G4NDE9"/>
    <dbReference type="GeneID" id="2674886"/>
    <dbReference type="KEGG" id="mgr:MGG_00930"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00930"/>
    <dbReference type="eggNOG" id="KOG0207">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_0_2_1"/>
    <dbReference type="InParanoid" id="G4NDE9"/>
    <dbReference type="OMA" id="DVIRVPH"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000068">
        <property type="entry name" value="Copper resistance-associated P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000043">
        <property type="entry name" value="Copper-transporting ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF32">
        <property type="entry name" value="COPPER RESISTANCE P-TYPE ATPASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="406"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="700"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="745"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1102"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1136"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="228"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="161"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA48438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1204" mass="130030" checksum="06535536A29AB686" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDF5</accession>
    <name>G4NDF5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_17342</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718028.1">
        <property type="nucleotide sequence ID" value="XM_003717980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDF5"/>
    <dbReference type="SMR" id="G4NDF5"/>
    <dbReference type="FunCoup" id="G4NDF5">
        <property type="interactions" value="250"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NDF5"/>
    <dbReference type="GeneID" id="12984004"/>
    <dbReference type="KEGG" id="mgr:MGG_17342"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17342"/>
    <dbReference type="eggNOG" id="KOG3429">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089470_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDF5"/>
    <dbReference type="OMA" id="WYNSFDA"/>
    <dbReference type="OrthoDB" id="270639at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016150">
        <property type="term" value="F:translation release factor activity, codon nonspecific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070126">
        <property type="term" value="P:mitochondrial translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052104">
        <property type="entry name" value="Mito_Release_Factor_mL62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075:SF54">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="3">
        <location>
            <begin position="61"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="191" mass="21576" checksum="4C15850C6CA47A71" modified="2011-12-14" version="1">MFRLQALTRTVLKLTHPTRPLVLKRPFRRGANSIELDPIALNEARDWKKSATANILPPGQTSYSRSSGPGGQHVNKTESKATTTWPLDVLLPCLPRVLHSSLKESKYYVKGTNSIAMQAQTSRSRDVNAQENRNKLFEEIQRIYTDTVPGETTQATTDKYKALEKFYNKVRLASKKHHSAKKNFRRGGPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDM4</accession>
    <name>G4NDM4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fungal cellulose binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718893.1">
        <property type="nucleotide sequence ID" value="XM_003718845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDM4"/>
    <dbReference type="SMR" id="G4NDM4"/>
    <dbReference type="GeneID" id="2674593"/>
    <dbReference type="KEGG" id="mgr:MGG_00215"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00215"/>
    <dbReference type="eggNOG" id="ENOG502RS04">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015101_4_2_1"/>
    <dbReference type="InParanoid" id="G4NDM4"/>
    <dbReference type="OMA" id="WGNNYHP"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466846" evidence="2">
        <location>
            <begin position="22"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="308" mass="32527" checksum="C4D327D716634101" modified="2011-12-14" version="1">MPSKLTVLASGALLLTSVGSAAVPCSSPQYLVTFGDSYSQTGFNTSLAKPTASNPLGNPALPGWTSSGGLNYVGQLAGKTVGNGGAAPVLSYNFADGGATTDSAIVAPYAPTVRSFVDQVAVFEQTLGARPRSEGWADWTAEDALFGVWMGVNDVGNSHWLANATDVVDALTLRYFDGLDALYEAGGRNFYLLTVPPTERSPLMMSSNSSPTLVPMLEYYRKSISSQLAVWETSHDDADVRIVDSVPAFNIPLDDPTSYGAPNASCYGAPGTAEGGKSCLWFNDYHPAIEIHKMVAKAVADAWKGKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDU2</accession>
    <name>G4NDU2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_17505</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718908.1">
        <property type="nucleotide sequence ID" value="XM_003718860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDU2"/>
    <dbReference type="SMR" id="G4NDU2"/>
    <dbReference type="FunCoup" id="G4NDU2">
        <property type="interactions" value="805"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NDU2"/>
    <dbReference type="GeneID" id="12985052"/>
    <dbReference type="KEGG" id="mgr:MGG_17505"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17505"/>
    <dbReference type="eggNOG" id="KOG2028">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017985_0_1_1"/>
    <dbReference type="InParanoid" id="G4NDU2"/>
    <dbReference type="OMA" id="RIILSQC"/>
    <dbReference type="OrthoDB" id="10265467at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18139">
        <property type="entry name" value="HLD_clamp_RarA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3710.10:FF:000005">
        <property type="entry name" value="AAA family ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000001">
        <property type="entry name" value="Putative AAA family ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000137">
        <property type="entry name" value="Replication-associated recombination protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3710.10">
        <property type="entry name" value="DNA polymerase III clamp loader subunits, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051314">
        <property type="entry name" value="AAA_ATPase_RarA/MGS1/WRNIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779:SF7">
        <property type="entry name" value="ATPASE WRNIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779">
        <property type="entry name" value="WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51908">
        <property type="entry name" value="ZF_UBZ4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBZ4-type" evidence="12">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="27"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA49324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="575" mass="61615" checksum="93BECD4148CCBA1E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE20</accession>
    <name>G4NE20_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosome biogenesis protein Rrp14-C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_00840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718139.1">
        <property type="nucleotide sequence ID" value="XM_003718091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE20"/>
    <dbReference type="SMR" id="G4NE20"/>
    <dbReference type="FunCoup" id="G4NE20">
        <property type="interactions" value="303"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NE20"/>
    <dbReference type="GeneID" id="2674626"/>
    <dbReference type="KEGG" id="mgr:MGG_00840"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00840"/>
    <dbReference type="eggNOG" id="KOG2885">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018300_1_1_1"/>
    <dbReference type="InParanoid" id="G4NE20"/>
    <dbReference type="OMA" id="ITSTQWQ"/>
    <dbReference type="OrthoDB" id="444809at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029190">
        <property type="entry name" value="Rrp14/SURF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029188">
        <property type="entry name" value="Rrp14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007019">
        <property type="entry name" value="SURF6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369:SF0">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15459">
        <property type="entry name" value="RRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04935">
        <property type="entry name" value="SURF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA-processing protein 14 N-terminal" evidence="6">
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="553" mass="61017" checksum="D8B274F0C9CE672F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE33</accession>
    <name>G4NE33_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="3" type="ORF">MGG_00830</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_003718104.1"/>
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    <dbReference type="STRING" id="242507.G4NE33"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
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    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF8">
        <property type="entry name" value="DUF500 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G07310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
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        <property type="entry name" value="Ysc84"/>
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        <location>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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            <dbReference type="Pfam" id="PF04366"/>
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    </evidence>
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            <dbReference type="EMBL" id="EHA48568.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEN9</accession>
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            <fullName evidence="11">Palmitoyltransferase PFA4</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
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            <fullName evidence="11">Protein S-acyltransferase</fullName>
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        <alternativeName>
            <fullName evidence="11">Protein fatty acyltransferase 4</fullName>
        </alternativeName>
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        <name evidence="11" type="primary">PFA4</name>
        <name evidence="15" type="ORF">MGG_00747</name>
    </gene>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11 12">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003718253.1">
        <property type="nucleotide sequence ID" value="XM_003718205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEN9"/>
    <dbReference type="FunCoup" id="G4NEN9">
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    </dbReference>
    <dbReference type="STRING" id="242507.G4NEN9"/>
    <dbReference type="GeneID" id="2674417"/>
    <dbReference type="KEGG" id="mgr:MGG_00747"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00747"/>
    <dbReference type="eggNOG" id="KOG1314">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_027721_8_1_1"/>
    <dbReference type="InParanoid" id="G4NEN9"/>
    <dbReference type="OMA" id="WEIERHK"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03199">
        <property type="entry name" value="DHHC_PAT_PFA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033682">
        <property type="entry name" value="PFA4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0564">Palmitate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="14">
        <location>
            <begin position="110"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="251"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="424"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="464"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="active site" description="S-palmitoyl cysteine intermediate" evidence="11">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA48669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="495" mass="56497" checksum="93229CC3C3B574C8" modified="2011-12-14" version="1">MAPLTGPVTTGLQIFAIPGVVLLIAFLGYASQWVFHTPDLQPGPLSKNQIITFNLLLLNLWWNYYKACTVPPGTYTHARPPSGDDDVDDKTKGKKQEDERQKPMTPAAGQRWCRKCDAPKPPRAHHCRHCRRCIPKMDHHCPWTGNCVSMQTFPYFYRFLVSTNLALWYLSRLLYLRFRALFDERNLPAYLGPSPTRIALLTVVAIACALVSLALGILLTTTTKAWLFNRTMIEDWEVERHESLVGRQARGGSTWWASEEEEGGEESSSEETTTPSNGQKTLRRVEFPYDIGIWNNMCQAMGTRNFLAWFWPFAGGPTVSRTAGSGVGWDWEENGFNAQAGMWPPPDPDKQRRGHWRGNADTAVKLPTYATPEEEKAAFKARQERDQRLRRRRQLMEAQQGSGIFAELEEDEELEDLFPEQRKREKYEKGLDGEPGWTNADGERLRDFGVDEDSDDVVEDDIVPHNADFDHDEDEDVPLGELLRRRRVASRNPDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEZ9</accession>
    <name>G4NEZ9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiol methyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_00698</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718309.1">
        <property type="nucleotide sequence ID" value="XM_003718261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEZ9"/>
    <dbReference type="SMR" id="G4NEZ9"/>
    <dbReference type="GeneID" id="2674986"/>
    <dbReference type="KEGG" id="mgr:MGG_00698"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00698"/>
    <dbReference type="eggNOG" id="ENOG502QS1V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056435_7_0_1"/>
    <dbReference type="InParanoid" id="G4NEZ9"/>
    <dbReference type="OMA" id="RDFISVW"/>
    <dbReference type="OrthoDB" id="276151at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183:SF6">
        <property type="entry name" value="CYSTEINE SULFINATE DESULFINASE_CYSTEINE DESULFURASE AND RELATED ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA48725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30477" checksum="B7C243CF9A468F67" modified="2011-12-14" version="1">MGTPEQTNKLSNLFLDQPLSEHGKRWDGLWKEDYTPWDRAGPSMALYDVLTGRPDLVPPPTGGQKKRALVPGCGRGYDVLLLSRLGYDVWGLDYSEEATKQSIIYEKKVEQGDDGTYAELEREGVKKGKVTWLTGDFFSDEWVNKAGVQQFDLTYDYTFLCALPISARPAWARRMADLLAHEGRLVCLQWPTAKPWSGGGPPWGVLPEHYIAQLARPGEKVEYESDGKIPAQAMPKVVEQGGLRRLELVVPSRTHNSGIADGVLHDRIAVFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF89</accession>
    <name>G4NF89_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ecp2 effector protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719611.1">
        <property type="nucleotide sequence ID" value="XM_003719563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF89"/>
    <dbReference type="STRING" id="242507.G4NF89"/>
    <dbReference type="GeneID" id="2677132"/>
    <dbReference type="KEGG" id="mgr:MGG_04208"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04208"/>
    <dbReference type="eggNOG" id="ENOG502RGCY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062877_0_0_1"/>
    <dbReference type="InParanoid" id="G4NF89"/>
    <dbReference type="OMA" id="YHFFISE"/>
    <dbReference type="OrthoDB" id="3836772at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466211" description="Ecp2 effector protein domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="33546" checksum="07C2759948B82B64" modified="2011-12-14" version="1">MRNLISLCLLATLAAQAAGQAIGNWTIYRFSRNCTSAVEPPKDQNRCSYHFFISEKPVGAPDASFQQCTIHVFSTWLPATQIPWVAVPCLENTDVSKYAISSGWNSNGFITVNVMNLFTLENAYFGYDDKDLVGGAEVANKTERAYKFGTFEPLRPGGGERLSMEQRREEALVQRRDDCDAAWWVVKKLQRRIDMSNHVKLGFVLQRCGMKDARCDVLTEAANFTRGIDARLDDFHDKPCDNNKDLHISWGYKADTDGGVMTIEDRKMRLRAFLGWDHVNDQITIEKEARGRVEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFW1</accession>
    <name>G4NFW1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-binding Rossmann fold oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719285.1">
        <property type="nucleotide sequence ID" value="XM_003719237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFW1"/>
    <dbReference type="SMR" id="G4NFW1"/>
    <dbReference type="STRING" id="242507.G4NFW1"/>
    <dbReference type="GeneID" id="2678889"/>
    <dbReference type="KEGG" id="mgr:MGG_08695"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08695"/>
    <dbReference type="eggNOG" id="ENOG502QV7T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052304_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFW1"/>
    <dbReference type="OMA" id="AMGDLRF"/>
    <dbReference type="OrthoDB" id="408743at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF2">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="154"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="437" mass="48547" checksum="67ED1C0853057572" modified="2011-12-14" version="1">MTGSKPKKRYALVGTGGRAGFYYTAIAKTYSSTSEVVAFCDTNQTRMDYANAQLAQLGHGPVPTYKAPGDGGSAFDTMVAETKPDEIIVTTIDRTHHTYIVRALELGCNVVTEKPMTIDGPRCREIFDAVERTGNRVRVTFNYRYAPHNTKVAELIRSGAIGTVTSVHFEWMLNTSHGADYFRRWHRDRRNSGGLLVHKSTHHFDLVNFWLRTRPATVYAQGDLRFYGRDNAEARGETRFYARAHGSDVARADPFALHLEDHPSLRAMYLDAEHEDAYHRDQSVFSDGISIEDTMSLLVRYRSGAVMTYSLTAYAPWEGFRVSFNGTGGRLEMEVVENSYVNAGGEQAEEGSLERRSIVLRRLLQKPEEIELQDSVGAHGGGDSVLLQDLFGEPVSDEYMRAASHLDGALSILTGIAANRSIATGQVVNVDDVLHIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG57</accession>
    <name>G4NG57_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAUS augmin-like complex subunit 6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_12243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719381.1">
        <property type="nucleotide sequence ID" value="XM_003719333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG57"/>
    <dbReference type="SMR" id="G4NG57"/>
    <dbReference type="STRING" id="242507.G4NG57"/>
    <dbReference type="GeneID" id="2681750"/>
    <dbReference type="KEGG" id="mgr:MGG_12243"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12243"/>
    <dbReference type="eggNOG" id="ENOG502S4RN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013984_0_0_1"/>
    <dbReference type="InParanoid" id="G4NG57"/>
    <dbReference type="OMA" id="RVHCVEW"/>
    <dbReference type="OrthoDB" id="5575722at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028163">
        <property type="entry name" value="HAUS_6_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14661">
        <property type="entry name" value="HAUS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAUS augmin-like complex subunit 6 N-terminal" evidence="2">
        <location>
            <begin position="53"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="572"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="623"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="801" mass="89044" checksum="264089DB035938A0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG81</accession>
    <name>G4NG81_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_16615</name>
        <name evidence="3" type="ORF">MGG_17612</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711280.1">
        <property type="nucleotide sequence ID" value="XM_003711232.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719405.1">
        <property type="nucleotide sequence ID" value="XM_003719357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG81"/>
    <dbReference type="SMR" id="G4NG81"/>
    <dbReference type="GeneID" id="12985840"/>
    <dbReference type="GeneID" id="12987004"/>
    <dbReference type="KEGG" id="mgr:MGG_16615"/>
    <dbReference type="KEGG" id="mgr:MGG_17612"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16615"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17612"/>
    <dbReference type="eggNOG" id="ENOG502SYTK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122022_0_0_1"/>
    <dbReference type="OMA" id="ANCVRAN"/>
    <dbReference type="OrthoDB" id="3555737at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="199" mass="21616" checksum="1A6B304F1395FA86" modified="2011-12-14" version="1">MPSCSPCRAKGAASCQVSPQDSARCVECVRSNRSGCDVLGLSAAQIRHIGRQHSKLDAEVEALEEQIHVQQAKLLRLRKQKKLWFEKMMRAVSRGIDDLEELDRVEREEAEQEERRRSTEVLPEMSLESLLPDSNFVWDSTFPMGPLNPSLLDEINVLAQHSVGSSGGMVSSPGRPLTSGNDPTPDSIGGAVPGNPGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGU8</accession>
    <name>G4NGU8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719825.1">
        <property type="nucleotide sequence ID" value="XM_003719777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGU8"/>
    <dbReference type="GeneID" id="12986244"/>
    <dbReference type="KEGG" id="mgr:MGG_14922"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14922"/>
    <dbReference type="HOGENOM" id="CLU_2483795_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGU8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="87" mass="9672" checksum="14EFC238CB2052ED" modified="2011-12-14" version="1">MYLSNWIRGFDEVEQYVTGPTTNGPSKSSLRVYLTSCTHVSDGQLPERYNECVSAAAAMVAPLYLSSSQLPINSRSAPKYPLDKRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHA3</accession>
    <name>G4NHA3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719980.1">
        <property type="nucleotide sequence ID" value="XM_003719932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHA3"/>
    <dbReference type="SMR" id="G4NHA3"/>
    <dbReference type="STRING" id="242507.G4NHA3"/>
    <dbReference type="ESTHER" id="mago7-a4r4e9">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="GeneID" id="2677483"/>
    <dbReference type="KEGG" id="mgr:MGG_03896"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03896"/>
    <dbReference type="eggNOG" id="ENOG502QTPE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051715_1_0_1"/>
    <dbReference type="InParanoid" id="G4NHA3"/>
    <dbReference type="OMA" id="WHPSYFR"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="61"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="359" mass="40083" checksum="C2CC3626FF706850" modified="2011-12-14" version="1">MVGLHLSYRWLRWTKPSEKPESLPDGVERHFVKTPLGDIEVLYSGPSEEATPTTSTPRQPLFFVHGGMGSAWVWLEYMRFLSSHGIPCYAVSMRGHGNSWHPSYIRMVFFTPRSALAQDVVAAIRWTQQREQGAEVVLVGHSSGGGMLQGILSEGLVSASGLVLAGAVPGFGSMGVYMNWWRADPWFALRMMLHGWHSNSPLSHPALVKNIFFSNEVSDSYVVNFFKHSNSYESYFWPFSMMRPFVKANSLLKQLGGISGWDRQRILILGGGGDKIMTVPIMQKLASYYRHGVLQLVGEDKLALEAVEDVEPLAGEGGLDDAGQGVQFCIVPKVGHHMQNDVHWEIGARKLLEFYRQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIL7</accession>
    <name>G4NIL7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
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                <person name="Ma L.J."/>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
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                <person name="Ma L.J."/>
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                <person name="Nusbaum C."/>
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    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
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                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">70-15</strain>
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    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="EHA46757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721500.1">
        <property type="nucleotide sequence ID" value="XM_003721452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EGW7"/>
    <dbReference type="GeneID" id="12986096"/>
    <dbReference type="KEGG" id="mgr:MGG_18091"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18091"/>
    <dbReference type="HOGENOM" id="CLU_3377265_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ70610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="34" mass="4189" checksum="0981B8267376C87D" modified="2011-12-14" version="1">MFYYCMRCRMPLLMLTIMDMNGMGLREHCQKQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHB0</accession>
    <name>G5EHB0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGCH7_ch7g886</name>
        <name evidence="7" type="ORF">MGG_03083</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15</strain>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">70-15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EAQ71479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720590.1">
        <property type="nucleotide sequence ID" value="XM_003720542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHB0"/>
    <dbReference type="SMR" id="G5EHB0"/>
    <dbReference type="STRING" id="242507.G5EHB0"/>
    <dbReference type="GeneID" id="2682636"/>
    <dbReference type="KEGG" id="mgr:MGG_03083"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03083"/>
    <dbReference type="eggNOG" id="ENOG502QUV4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_567492_0_0_1"/>
    <dbReference type="OMA" id="WESTYTI"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF91">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G12070)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="296"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EAQ71479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA45847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="481" mass="51422" checksum="4DB3AA1D1B66EB7B" modified="2011-12-14" version="1">MGKDAQDKKPDLYGNSADFGPPGVGNHEIADSSSIPICGLVGIMGFSHARNIPSILKPVVPTTHSLVELRISEIQKRRLQERLMTSLLPSWDMAERQTSIVFSSWESTYTIGDFPWTGSSAFTLLSPTESEEEQRGSKSDMHLKSYEGHGGVLVHMAIFISPFTILAICLLWAVSNAAYVAVADIKPAVAIVAETEAAGAPLQSSEIRQLTDEVVDRIASDELTAGHHATAACKIFPGDPGWPVESVWNVFNALLGNALIPTKPLGAPYPTANYWPIFQGRTCKAKNDASGSECTIGGYPAYAVNITSVAQMQLAINFARTTNMRLVIKNTGHCYLGKSLGAGALSLWMHNMRDIDFLPDYKGPGYSGPALKLAAGVTVREAYEAAEKYNVTILGAISWSVGYAGGMITGGGQNPLAGIYGMAADHVVAFQLVTADGRLRTVSEDESPTPGSARSRGSGIPVVCFMPSPPWEVRGGWSRMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHD9</accession>
    <name>G5EHD9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g1054</name>
        <name evidence="3" type="ORF">MGG_10286</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720551.1">
        <property type="nucleotide sequence ID" value="XM_003720503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHD9"/>
    <dbReference type="GeneID" id="2681938"/>
    <dbReference type="KEGG" id="mgr:MGG_10286"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10286"/>
    <dbReference type="HOGENOM" id="CLU_2158923_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="111" mass="12139" checksum="58B6C5647F883C02" modified="2011-12-14" version="1">MSSNDESSNDTTNEEAASLPETIYFEEDGAYVAIGQRQVVVSGAREPVKAYLTRFFDQYDDVVVWHMMVLEEPRDPKADCSGDGSEASGSGPQNVEILLQSSHRLTSLAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHF1</accession>
    <name>G5EHF1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g947</name>
        <name evidence="3" type="ORF">MGG_16600</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711234.1">
        <property type="nucleotide sequence ID" value="XM_003711186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHF1"/>
    <dbReference type="STRING" id="242507.G5EHF1"/>
    <dbReference type="GeneID" id="12986984"/>
    <dbReference type="KEGG" id="mgr:MGG_16600"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16600"/>
    <dbReference type="HOGENOM" id="CLU_1326611_0_0_1"/>
    <dbReference type="OrthoDB" id="10605499at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="207" mass="22711" checksum="60DABE0727203334" modified="2011-12-14" version="1">MSLSNPCQVRQKTPKGHNLLGIVGPGAGSRGGTGQHQPQPPHLKQVGSGRSFGPAIHSRMSSGVGTLTRRRDGLDLVVGQRYYIVPVRRERVVMGAELIDKRWCEDQHQLGPCRAAGRGPRWGGWIREAKESGTGRLVDRLSCKSLGPGFPAPRGLPCLKKLAETWRSPAPPNHPSGHDFIIFMWSVKARKVSARFNDSCGWKAIRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-07-03" modified="2025-02-05" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHH0</accession>
    <name>BAS3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Biotrophy-associated secreted protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BAS3</name>
        <name type="ORF">MGG_11610</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2009" name="Plant Cell" volume="21" first="1273" last="1290">
            <title>Interaction transcriptome analysis identifies Magnaporthe oryzae BAS1-4 as Biotrophy-associated secreted proteins in rice blast disease.</title>
            <authorList>
                <person name="Mosquera G."/>
                <person name="Giraldo M.C."/>
                <person name="Khang C.H."/>
                <person name="Coughlan S."/>
                <person name="Valent B."/>
            </authorList>
            <dbReference type="PubMed" id="19357089"/>
            <dbReference type="DOI" id="10.1105/tpc.107.055228"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <scope>INDUCTION</scope>
        <scope>FUNCTION</scope>
        <scope>SUBCELLULAR LOCATION</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted effector involved in biotrophic colonization of plant cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
        <text evidence="2">Localizes to the appressorial penetration site and outlines the primary hyphae.</text>
    </comment>
    <comment type="induction">
        <text evidence="2">Expression is highly up-regulated in invasive hyphae.</text>
    </comment>
    <dbReference type="EMBL" id="FJ807766">
        <property type="protein sequence ID" value="ACQ73208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718811.1">
        <property type="nucleotide sequence ID" value="XM_003718763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHH0"/>
    <dbReference type="STRING" id="242507.G5EHH0"/>
    <dbReference type="EnsemblFungi" id="MGG_11610T0">
        <property type="protein sequence ID" value="MGG_11610T0"/>
        <property type="gene ID" value="MGG_11610"/>
    </dbReference>
    <dbReference type="GeneID" id="5050770"/>
    <dbReference type="KEGG" id="mgr:MGG_11610"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11610"/>
    <dbReference type="eggNOG" id="ENOG502T4TA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163491_0_0_1"/>
    <dbReference type="InParanoid" id="G5EHH0"/>
    <dbReference type="OMA" id="SVCRTQC"/>
    <dbReference type="OrthoDB" id="4848580at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007915055" description="Biotrophy-associated secreted protein 3">
        <location>
            <begin position="21"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="19357089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="3">
        <source>
            <dbReference type="PubMed" id="19357089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACQ73208.1"/>
        </source>
    </evidence>
    <sequence length="113" mass="12039" checksum="68A78BEF1D55BD7C" modified="2011-12-14" version="1" precursor="true">MQFSTVSFAIFAILPAMVAAMPAETSPVPKPALPVFEELCPDAERQKCAESTDNLKRCLQINGASICVIDCGSQTTCRTQCKQQLKNEKANGFCTVGDNPCICNLNGAANSAH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-09-13" modified="2025-06-18" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>Q52B63</accession>
    <accession>A4RM83</accession>
    <accession>G4MUM6</accession>
    <name>CWC22_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Pre-mRNA-splicing factor CWC22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">CWC22</name>
        <name type="ORF">MGG_10180</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CWC22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713806.1">
        <property type="nucleotide sequence ID" value="XM_003713758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q52B63"/>
    <dbReference type="SMR" id="Q52B63"/>
    <dbReference type="FunCoup" id="Q52B63">
        <property type="interactions" value="895"/>
    </dbReference>
    <dbReference type="STRING" id="242507.Q52B63"/>
    <dbReference type="EnsemblFungi" id="MGG_10180T0">
        <property type="protein sequence ID" value="MGG_10180T0"/>
        <property type="gene ID" value="MGG_10180"/>
    </dbReference>
    <dbReference type="GeneID" id="2681807"/>
    <dbReference type="KEGG" id="mgr:MGG_10180"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10180"/>
    <dbReference type="eggNOG" id="KOG2140">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006308_0_2_1"/>
    <dbReference type="InParanoid" id="Q52B63"/>
    <dbReference type="OMA" id="ILTEDMR"/>
    <dbReference type="OrthoDB" id="3938623at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000004">
        <property type="entry name" value="pre-mRNA-splicing factor CWC22 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF3">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0508">mRNA splicing</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0747">Spliceosome</keyword>
    <feature type="chain" id="PRO_0000215673" description="Pre-mRNA-splicing factor CWC22">
        <location>
            <begin position="1"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G" evidence="2">
        <location>
            <begin position="159"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="MI" evidence="2">
        <location>
            <begin position="444"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="405"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="639"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="655"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="675"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="687"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="753"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="773"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="817"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="837"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="869"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="898"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="907" mass="102101" checksum="56F5F6D5721952F5" modified="2005-06-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4B8</accession>
    <name>A0A151V4B8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845939.1">
        <property type="nucleotide sequence ID" value="XM_016990550.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="mgr:MGG_14982"/>
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    <dbReference type="InParanoid" id="A0A151V4B8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KYQ30435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="102" mass="10971" checksum="BE002A0560ECB704" modified="2016-06-08" version="1">MTVGDLGRRASDAEDAGKKRLKMQVWKEYGVVLPSGNGRQLASRLKAQKCAACSMLDDWGSLKVAAMDGAASVLPSTWGLCIVGPHKRGFLNFRHNRGPANS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-02-08" modified="2026-01-28" version="110" xmlns="https://uniprot.org/uniprot">
    <accession>A4R3M4</accession>
    <accession>G4NI24</accession>
    <name>LIS1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nuclear distribution protein PAC1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Lissencephaly-1 homolog</fullName>
            <shortName evidence="1">LIS-1</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">nudF homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PAC1</name>
        <name evidence="1" type="synonym">LIS1</name>
        <name type="ORF">MGG_09369</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Self-associates. Interacts with NDL1 and dynein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle pole</location>
        </subcellularLocation>
        <text evidence="1">Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Dimerization mediated by the LisH domain may be required to activate dynein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LIS1/nudF family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720251.1">
        <property type="nucleotide sequence ID" value="XM_003720203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R3M4"/>
    <dbReference type="SMR" id="A4R3M4"/>
    <dbReference type="FunCoup" id="A4R3M4">
        <property type="interactions" value="48"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4R3M4"/>
    <dbReference type="EnsemblFungi" id="MGG_09369T0">
        <property type="protein sequence ID" value="MGG_09369T0"/>
        <property type="gene ID" value="MGG_09369"/>
    </dbReference>
    <dbReference type="GeneID" id="2680413"/>
    <dbReference type="KEGG" id="mgr:MGG_09369"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09369"/>
    <dbReference type="eggNOG" id="KOG0295">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_15_1"/>
    <dbReference type="InParanoid" id="A4R3M4"/>
    <dbReference type="OMA" id="RGTCLMT"/>
    <dbReference type="OrthoDB" id="10264588at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051012">
        <property type="term" value="P:microtubule sliding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0023052">
        <property type="term" value="P:signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000342">
        <property type="entry name" value="Nuclear distribution protein PAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.960.30:FF:000002">
        <property type="entry name" value="Platelet-activating factor acetylhydrolase ib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03141">
        <property type="entry name" value="lis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017252">
        <property type="entry name" value="Dynein_regulator_LIS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037190">
        <property type="entry name" value="LIS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056795">
        <property type="entry name" value="PAC1-like_LisH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24951">
        <property type="entry name" value="LisH_PAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037647">
        <property type="entry name" value="Dynein_regulator_Lis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109925">
        <property type="entry name" value="Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0175">Coiled coil</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0206">Cytoskeleton</keyword>
    <keyword id="KW-0493">Microtubule</keyword>
    <keyword id="KW-0498">Mitosis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0853">WD repeat</keyword>
    <feature type="chain" id="PRO_0000405082" description="Nuclear distribution protein PAC1">
        <location>
            <begin position="1"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="LisH" evidence="1">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="repeat" description="WD 1">
        <location>
            <begin position="114"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="WD 2">
        <location>
            <begin position="157"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="WD 3">
        <location>
            <begin position="201"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="WD 4">
        <location>
            <begin position="251"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="WD 5">
        <location>
            <begin position="295"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="repeat" description="WD 6">
        <location>
            <begin position="357"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="repeat" description="WD 7">
        <location>
            <begin position="401"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="WD 8">
        <location>
            <begin position="446"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03141"/>
        </source>
    </evidence>
    <sequence length="461" mass="50783" checksum="4A6E0C5C47BC6873" modified="2012-01-25" version="3">MTSILTPRQAEELHKAIIAYLSANNLSSSATALRTELGLAEDVFDAATAKKYEGLIEKKWTSVVRLQKKIMDLESRNNALQSELDNATPLSLAKRNTDPTAWLPAPRPRYSLESHQNTINCIAFHPVYSSIASGSDDCTIKIWDWELGELERTIKSHTRPVLDVDFGGPRGGILLASCSSDLTIKLWDPSDDYKNIRTLPGHDHSVSAIRFMPSGASGAAMSGNLLVSASRDMTLKIWDVSTGFCLKTIRGHTAWIRDVYPSLDGRYLLSTGDDSTVRLWDLSVTNPENRLTMIGHDHYIECCALAPPSSYPFLSRLAGLKKPPAATSTAEFMASGSRDKTIKLWDARGTLLKTLIGHDNWVRALVFHPGGRYLLSVSDDKTLRCWDLEQDGKCVKTIGDVHERFVTCLRWAPGVVMDAPAEADGQSNGTPRKKTEAAPAVRIRCVIATGSVDMKLRIFAN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-04-29" modified="2025-06-18" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>A4RF31</accession>
    <accession>G4NBU0</accession>
    <name>ATP23_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber>3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">ATP23</name>
        <name type="ORF">MGG_00480</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Mitochondrion inner membrane</location>
            <topology>Peripheral membrane protein</topology>
            <orientation>Intermembrane side</orientation>
        </subcellularLocation>
        <text evidence="1">Associates loosely with the inner membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M76 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718582.1">
        <property type="nucleotide sequence ID" value="XM_003718534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RF31"/>
    <dbReference type="FunCoup" id="A4RF31">
        <property type="interactions" value="490"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RF31"/>
    <dbReference type="MEROPS" id="M76.002"/>
    <dbReference type="EnsemblFungi" id="MGG_00480T0">
        <property type="protein sequence ID" value="MGG_00480T0"/>
        <property type="gene ID" value="MGG_00480"/>
    </dbReference>
    <dbReference type="GeneID" id="2674715"/>
    <dbReference type="KEGG" id="mgr:MGG_00480"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00480"/>
    <dbReference type="eggNOG" id="KOG3314">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079125_0_0_1"/>
    <dbReference type="InParanoid" id="A4RF31"/>
    <dbReference type="OMA" id="EAHQNCV"/>
    <dbReference type="OrthoDB" id="285308at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00142">
        <property type="entry name" value="ZINC_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0482">Metalloprotease</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000330066" description="Mitochondrial inner membrane protease ATP23">
        <location>
            <begin position="1"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="273" mass="31660" checksum="DEB457D990FBE0C3" modified="2007-05-15" version="1">MASPQDNTPSGATPKPQTHEETPDQVKLRINGGERLNIRKNNPAETGFDPATSKWVNYFKVLTGSMTKEGQFHYREHLYRTNEERDLRRCEEQRDWLFRYSPVVRYMRDQIRLLGGELDADNVVCRRCPSRLTADGRILGQAGGFSPQHGILVCANSIRDRKHLEDTLAHEMVHAYDHLRWQVDFVGEKDLRHAACTEIRASMLSGECRWTREAFGRGNWTVTQQFQNCVRSRAIMSVRARARCRDTEHATKVVNQVWDSCFSDTRPFDEIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MK89</accession>
    <name>G4MK89_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709292.1">
        <property type="nucleotide sequence ID" value="XM_003709244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MK89"/>
    <dbReference type="GeneID" id="2681592"/>
    <dbReference type="KEGG" id="mgr:MGG_02495"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02495"/>
    <dbReference type="HOGENOM" id="CLU_1594867_0_0_1"/>
    <dbReference type="InParanoid" id="G4MK89"/>
    <dbReference type="OMA" id="PPFCSHQ"/>
    <dbReference type="OrthoDB" id="5228980at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="167" mass="18202" checksum="7FCA2A3FE06CDECB" modified="2011-12-14" version="1">MQDQSPESACAAAGLFYLPGKPPFCSHQQLPRSIPSLPPKKSSRMPVTTRSASRRMAAAQTAAAKPSQPRIKYRRVNGKPGLLISPPEWVTPTRRVVLTTGARGQRLTRIRGPGDRLLVRVPDKEAATKTSNRRLSTFVRAGRTWIRIRPAVQEAGGVATGSQKQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKB2</accession>
    <name>G4MKB2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_02508</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709315.1">
        <property type="nucleotide sequence ID" value="XM_003709267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKB2"/>
    <dbReference type="SMR" id="G4MKB2"/>
    <dbReference type="STRING" id="242507.G4MKB2"/>
    <dbReference type="GeneID" id="2681605"/>
    <dbReference type="KEGG" id="mgr:MGG_02508"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02508"/>
    <dbReference type="eggNOG" id="ENOG502RM4B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1038557_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKB2"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF125">
        <property type="entry name" value="N-ACETYL-6-HYDROXYTRYPTOPHAN OXIDASE IVOB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465302" description="Tyrosinase copper-binding domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="99"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA56703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="268" mass="28924" checksum="7DB0F6E88BEB34AF" modified="2011-12-14" version="1">MRPFSCLAAFAALASTAAAIPTAQSAAPNGLEDAKRNFEKNVSGITRGKMAKLKDLTKEERLDYVNAVKCLMKLPAKTPQEVAPGAKSRVVCRLQRPAHPKRRFKVHYTGNFQAWHRWFVFNYERALGEECAYKGYQPYWGWAKHATAPENLGGNGAAIPHDGPVIAPPPGIKAPTIQLPPGLGGGPVTEGPFANMTITLGPVALTDVPPGPMGGLGHNPRPSKRDLAKQKGNKSILQRVRPIWERTITHTSLGGTSLPARLLALMTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKP3</accession>
    <name>G4MKP3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Endothelin-converting enzyme 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_06643</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709345.1">
        <property type="nucleotide sequence ID" value="XM_003709297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKP3"/>
    <dbReference type="SMR" id="G4MKP3"/>
    <dbReference type="STRING" id="242507.G4MKP3"/>
    <dbReference type="GeneID" id="2684816"/>
    <dbReference type="KEGG" id="mgr:MGG_06643"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06643"/>
    <dbReference type="eggNOG" id="KOG3624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006187_4_3_1"/>
    <dbReference type="InParanoid" id="G4MKP3"/>
    <dbReference type="OMA" id="FGWAQVW"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="11">
        <location>
            <begin position="119"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="10">
        <location>
            <begin position="575"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA56733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="779" mass="85845" checksum="A8DE897D5AD2181A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML90</accession>
    <name>G4ML90_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL32m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06727</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709438.1">
        <property type="nucleotide sequence ID" value="XM_003709390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML90"/>
    <dbReference type="SMR" id="G4ML90"/>
    <dbReference type="STRING" id="242507.G4ML90"/>
    <dbReference type="GeneID" id="2684900"/>
    <dbReference type="KEGG" id="mgr:MGG_06727"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06727"/>
    <dbReference type="eggNOG" id="KOG4080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129084_0_2_1"/>
    <dbReference type="InParanoid" id="G4ML90"/>
    <dbReference type="OMA" id="WLGGIWE"/>
    <dbReference type="OrthoDB" id="2014905at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051991">
        <property type="entry name" value="Mitoribosomal_protein_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA56826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="137" mass="15185" checksum="635E3B6BC5C6A9FA" modified="2011-12-14" version="1">MAAAMATQQLRLQLPRLSFLSSNSFATTYIRQLSLPLFPSVKFALPAISLGLPSIPSIPALLGEIWEGILRAVPKKKTSHMKKRHRQMAGKALKDQTAICKCPACGGLKRMHYLCPFCTEKIKKALKDSVEDHAEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLB9</accession>
    <name>G4MLB9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710261.1">
        <property type="nucleotide sequence ID" value="XM_003710213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLB9"/>
    <dbReference type="GeneID" id="12986265"/>
    <dbReference type="KEGG" id="mgr:MGG_16353"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16353"/>
    <dbReference type="HOGENOM" id="CLU_2688283_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLB9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465186" evidence="2">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="74" mass="7860" checksum="0BD11255AC13783F" modified="2011-12-14" version="1">MKLSLIAAVLATALPALAHEASAGTPLTVARRDVPIQADKLTAREATRARVSVQKRDAPPDPLKSRPDHKDNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLJ9</accession>
    <name>G4MLJ9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_16161</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709444.1">
        <property type="nucleotide sequence ID" value="XM_003709396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLJ9"/>
    <dbReference type="SMR" id="G4MLJ9"/>
    <dbReference type="STRING" id="242507.G4MLJ9"/>
    <dbReference type="GeneID" id="12984497"/>
    <dbReference type="KEGG" id="mgr:MGG_16161"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16161"/>
    <dbReference type="eggNOG" id="ENOG502SH73">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007091_1_0_1"/>
    <dbReference type="InParanoid" id="G4MLJ9"/>
    <dbReference type="OMA" id="VYNQEMR"/>
    <dbReference type="OrthoDB" id="4236860at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF130">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTO (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="84"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="112"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="191"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="871" mass="98272" checksum="78632BDB7717738D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLP3</accession>
    <name>G4MLP3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709488.1">
        <property type="nucleotide sequence ID" value="XM_003709440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLP3"/>
    <dbReference type="SMR" id="G4MLP3"/>
    <dbReference type="GeneID" id="2684945"/>
    <dbReference type="KEGG" id="mgr:MGG_06772"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06772"/>
    <dbReference type="eggNOG" id="KOG3017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035730_5_1_1"/>
    <dbReference type="InParanoid" id="G4MLP3"/>
    <dbReference type="OMA" id="DSMRVGC"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="73"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="231" mass="24174" checksum="FA42B366B0F5538A" modified="2011-12-14" version="1">MAHVPPGIGGFPTSTSASPSTLPPSSVTVIVSVTSVTTSTALTTSTTITATTSSTITTSTSTTTNTMVETQTPYVRTIIRHHDAHRANHSAPALAWSDSLAGTAQSIAETCIFQHNTTADSGDYGQNIVAGVPENQMGIVVTDTEPDLVDFSRWGHFSQLIWTSTAEVGCATVDCSSRQCGLQNVQGQPPYFTVCNYKPPGAPLGSPSIDGTFMCGSSINFSYSLVFGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM67</accession>
    <name>G4MM67_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">General alpha-glucoside permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_13086</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710360.1">
        <property type="nucleotide sequence ID" value="XM_003710312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM67"/>
    <dbReference type="SMR" id="G4MM67"/>
    <dbReference type="STRING" id="242507.G4MM67"/>
    <dbReference type="GeneID" id="5051493"/>
    <dbReference type="KEGG" id="mgr:MGG_13086"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13086"/>
    <dbReference type="eggNOG" id="KOG0637">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018303_1_1_1"/>
    <dbReference type="InParanoid" id="G4MM67"/>
    <dbReference type="OMA" id="MACAQEL"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA57748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="559" mass="60913" checksum="3EE24CF37E7064F2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMA2</accession>
    <name>G4MMA2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_14623</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003708652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMA2"/>
    <dbReference type="SMR" id="G4MMA2"/>
    <dbReference type="GeneID" id="5050580"/>
    <dbReference type="KEGG" id="mgr:MGG_14623"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14623"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_6_2_1"/>
    <dbReference type="InParanoid" id="G4MMA2"/>
    <dbReference type="OMA" id="TFQVGCR"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF2">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA56088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="615" mass="68366" checksum="B06F4291673417D7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMJ0</accession>
    <name>G4MMJ0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709580.1">
        <property type="nucleotide sequence ID" value="XM_003709532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMJ0"/>
    <dbReference type="SMR" id="G4MMJ0"/>
    <dbReference type="GeneID" id="12984559"/>
    <dbReference type="KEGG" id="mgr:MGG_16192"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16192"/>
    <dbReference type="HOGENOM" id="CLU_1678257_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMJ0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="157" mass="18167" checksum="0450A5F9F62A1656" modified="2011-12-14" version="1">MEENLQAHLARISVSERVSHCSITFRALFSHSAKVNIPLFPTTRNCRPKQPYAGHTARSSPFFRPHVHIKQMKNLQTIISRIRGRRLPIGSRLLEWWMVQKRDDGRSLWLPTGWRRYVPLLQDTSHTVRHQPVASQHNSTGDRAKLGHVRAHLNVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP73</accession>
    <name>G4MP73_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708944.1">
        <property type="nucleotide sequence ID" value="XM_003708896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP73"/>
    <dbReference type="SMR" id="G4MP73"/>
    <dbReference type="GeneID" id="12985720"/>
    <dbReference type="KEGG" id="mgr:MGG_16049"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16049"/>
    <dbReference type="eggNOG" id="KOG1075">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1030858_0_0_1"/>
    <dbReference type="InParanoid" id="G4MP73"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="270" mass="30217" checksum="44C98471632B1936" modified="2011-12-14" version="1">MFLMGIRIACTSDSMALLLRLKAKPAHRLAIFHLNKRLVQSHYRDRATPGHVTVQSAKELENVETIGNWFEKVFATKFENLQAPENAAFRKIIFKFNDVINGWFLNRTLREKKRSRSPSRSPTSSSERRSILITRTGTASSASKGRGTPINKSVIWAERAATPPAAAPTQILTPATRSYPIRTTSGNVPNSSATPSQSGRDRSQTPKRLTKQPSNRILIRVNNKLRMVTRKLYAVTTKLAELVSVLHSEILNAKRTPTGWGVTVAFEEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP77</accession>
    <name>G4MP77_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_02180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708948.1">
        <property type="nucleotide sequence ID" value="XM_003708900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP77"/>
    <dbReference type="SMR" id="G4MP77"/>
    <dbReference type="GeneID" id="2681038"/>
    <dbReference type="KEGG" id="mgr:MGG_02180"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02180"/>
    <dbReference type="eggNOG" id="ENOG502SP0W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139288_0_0_1"/>
    <dbReference type="InParanoid" id="G4MP77"/>
    <dbReference type="OMA" id="QIHQIAR"/>
    <dbReference type="OrthoDB" id="2772415at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="117" mass="12948" checksum="55382A1D3E3ACA52" modified="2011-12-14" version="1">MAPKGPFRLVTVNTAPERAKKLIGRMVEALKDQYTIDYVANCETIAEVEEKVKAAKPDVLFAASMWSADEAAQIEQIGRSIVPDVKFHAIPHGLQVERGPDAIVEHLLEMVPKLLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPI1</accession>
    <name>G4MPI1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Calpain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_15163</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkB family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710636.1">
        <property type="nucleotide sequence ID" value="XM_003710588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPI1"/>
    <dbReference type="SMR" id="G4MPI1"/>
    <dbReference type="STRING" id="242507.G4MPI1"/>
    <dbReference type="GeneID" id="12986393"/>
    <dbReference type="KEGG" id="mgr:MGG_15163"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15163"/>
    <dbReference type="eggNOG" id="KOG3200">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059836_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPI1"/>
    <dbReference type="OMA" id="KSPKTKW"/>
    <dbReference type="OrthoDB" id="541710at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032862">
        <property type="entry name" value="ALKBH6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="121"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA58024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="261" mass="29121" checksum="2AC312F00D4AC854" modified="2011-12-14" version="1">MTDNDNNSRAPTAAADLPRLPSSLREAIINSLPRTAFYISEFLSEEEERQILSKIDAAPKPRWKQLTHRRLQPWPSDLVNNTLLDAPLPAWLEDPVVTRLAAIPLASTTEDSIFSDSPHRRPNHVLINEYPSGVGIMPHKDGPAYHPVVCTVSLGGSLCLNIHKSKDDGTLESEPSWRVLQEPRSLLITTHDLYTNYLHGIADVNADEGLSEATVANWDLLRSKEPFVGGRNERTVRTSLTYRDVLKVSKLGNKFGAFVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPY1</accession>
    <name>G4MPY1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710681.1">
        <property type="nucleotide sequence ID" value="XM_003710633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPY1"/>
    <dbReference type="GeneID" id="12986410"/>
    <dbReference type="KEGG" id="mgr:MGG_16467"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16467"/>
    <dbReference type="HOGENOM" id="CLU_2223762_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPY1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="106" mass="11895" checksum="9FCA1B96FC2A776A" modified="2011-12-14" version="1">MTPAKKGVLRRCSLSQRAEMQKEKVQGRESSPMRNQETLRRKLNEAGATEQGRGSYFNAGPPGKDGHFQQKIKVAAFKHGAETWDEPVLTRCVDGERRQGKSHKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ91</accession>
    <name>G4MQ91_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09263</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709896.1">
        <property type="nucleotide sequence ID" value="XM_003709848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQ91"/>
    <dbReference type="SMR" id="G4MQ91"/>
    <dbReference type="STRING" id="242507.G4MQ91"/>
    <dbReference type="GeneID" id="2680281"/>
    <dbReference type="KEGG" id="mgr:MGG_09263"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09263"/>
    <dbReference type="eggNOG" id="ENOG502QT5J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004835_0_1_1"/>
    <dbReference type="InParanoid" id="G4MQ91"/>
    <dbReference type="OMA" id="RDKGTEC"/>
    <dbReference type="OrthoDB" id="5244761at2759"/>
    <dbReference type="PHI-base" id="PHI:2995"/>
    <dbReference type="PHI-base" id="PHI:889"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="388"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="656"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="719"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1183"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="393"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="659"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="722"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="752"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1226" mass="135611" checksum="B6432A0C6988A34C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRN9</accession>
    <name>G4MRN9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710074.1">
        <property type="nucleotide sequence ID" value="XM_003710026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRN9"/>
    <dbReference type="GeneID" id="12985328"/>
    <dbReference type="KEGG" id="mgr:MGG_16304"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16304"/>
    <dbReference type="HOGENOM" id="CLU_3069172_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRN9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="53" mass="5721" checksum="D03B9FB3C05C0D07" modified="2011-12-14" version="1">MLVLRVVLLESFNLLVFALVGLSRDHLLLLLFGFQLGNWGGGGVGVAQIGKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS69</accession>
    <name>G4MS69_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cellobiose dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_13809</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710939.1">
        <property type="nucleotide sequence ID" value="XM_003710891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS69"/>
    <dbReference type="SMR" id="G4MS69"/>
    <dbReference type="GeneID" id="5049029"/>
    <dbReference type="KEGG" id="mgr:MGG_13809"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13809"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011025_0_0_1"/>
    <dbReference type="InParanoid" id="G4MS69"/>
    <dbReference type="OMA" id="FYEAWTT"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1210:FF:000004">
        <property type="entry name" value="Cellobiose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF2">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G17620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465352" evidence="2">
        <location>
            <begin position="24"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="Cellobiose dehydrogenase-like cytochrome" evidence="5">
        <location>
            <begin position="31"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="280"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="4">
        <location>
            <begin position="671"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA58327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="815" mass="86803" checksum="876581CABB3ECC29" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS84</accession>
    <name>G4MS84_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rossmann-fold NAD(P)(+)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710954.1">
        <property type="nucleotide sequence ID" value="XM_003710906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS84"/>
    <dbReference type="SMR" id="G4MS84"/>
    <dbReference type="STRING" id="242507.G4MS84"/>
    <dbReference type="GeneID" id="2678166"/>
    <dbReference type="KEGG" id="mgr:MGG_04501"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04501"/>
    <dbReference type="eggNOG" id="ENOG502SIQW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022827_0_0_1"/>
    <dbReference type="InParanoid" id="G4MS84"/>
    <dbReference type="OMA" id="NMPVQAK"/>
    <dbReference type="OrthoDB" id="20105at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="625" mass="69315" checksum="F7343EAD77025CB2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSG5</accession>
    <name>G4MSG5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclohexadienyl dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714388.1">
        <property type="nucleotide sequence ID" value="XM_003714340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSG5"/>
    <dbReference type="SMR" id="G4MSG5"/>
    <dbReference type="STRING" id="242507.G4MSG5"/>
    <dbReference type="GeneID" id="2679190"/>
    <dbReference type="KEGG" id="mgr:MGG_01438"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01438"/>
    <dbReference type="eggNOG" id="ENOG502S7TA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_9_1_1"/>
    <dbReference type="InParanoid" id="G4MSG5"/>
    <dbReference type="OMA" id="KAYMLPR"/>
    <dbReference type="OrthoDB" id="406464at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35936:SF19">
        <property type="entry name" value="AMINO-ACID-BINDING PROTEIN YXEM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35936">
        <property type="entry name" value="MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Solute-binding protein family 3/N-terminal" evidence="2">
        <location>
            <begin position="22"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="261" mass="28569" checksum="41C930D2DF9AEEB0" modified="2011-12-14" version="1">MAAKTGGCSAPSQLDAIIARGHLKVGMTGAYKPFSYLDPDSASNSSSSGYIGADVDMAKSLSQAMGLTKDPEFVHATFANMTTEINEGRYDIGMTGVSITLARARLCFYSNPLIRVGKVATVRCEDASKYQSLAAIDVEGVRVATPSGGSNEVFDRANLKKAEILVYTETDNNIIFQAVVDKKADVMITDRVEAELQAKMHPGVLCAVNPEEPFSFEEIGYIMKRDVVLQQFVNQWLHVQQGSGAWNRTLQSWMDYPWPHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSJ3</accession>
    <name>G4MSJ3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_15702</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714416.1">
        <property type="nucleotide sequence ID" value="XM_003714368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSJ3"/>
    <dbReference type="SMR" id="G4MSJ3"/>
    <dbReference type="STRING" id="242507.G4MSJ3"/>
    <dbReference type="GeneID" id="12984656"/>
    <dbReference type="KEGG" id="mgr:MGG_15702"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15702"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_1_1"/>
    <dbReference type="InParanoid" id="G4MSJ3"/>
    <dbReference type="OMA" id="DPRYCAD"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="3">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="463" mass="50474" checksum="1A879CB2D65100B3" modified="2011-12-14" version="1">MSFHGTSGPVEVSFPRFVYNQSYAVLKGYEELGLPMLKDMNTGITAGVVFSPSSMQAINQSRCDARVAYLDPVMERPNMHVAVGQMATRLLLVDSTQGLISSTKDLPTPKRVQEVEFLPRRDSHSNNIHSSRVSASREVIMASGAIHTPTILQVSGIGPAYVLERLNITVQIELPGVGNNLQDHGMVGKDYDYKSPNIFTDRHLDGAKLAEAELLYKVNRTGPLTAPLISIVAFPSLQALTAEWNTLTGKYMLENFDRYLPDDAPPAVRQGYAKQSRLQLDILRQVDEPASEIMVDSTGRYTVAIQSTMSRGTVRPSGPNILKDNKPVIDPRYCAHPLDCEVAMLSFRMNARLMKTNAFIQGLSPSPSEPFASADDVADEENTAKLADFIQRGLGTEFHPAGTTAMLPFEDGGVVDTELRVYGTTNLRVVDAGIMPLLPAAHIQAAVYAVAEKAADLIKAVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSK1</accession>
    <name>G4MSK1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane protein 34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01467</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714424.1">
        <property type="nucleotide sequence ID" value="XM_003714376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSK1"/>
    <dbReference type="STRING" id="242507.G4MSK1"/>
    <dbReference type="GeneID" id="2679243"/>
    <dbReference type="KEGG" id="mgr:MGG_01467"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01467"/>
    <dbReference type="eggNOG" id="KOG2641">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012923_5_1_1"/>
    <dbReference type="InParanoid" id="G4MSK1"/>
    <dbReference type="OMA" id="HAIYFQV"/>
    <dbReference type="OrthoDB" id="5348404at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="430"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="507"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="394"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="536"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="562" mass="62554" checksum="86E1A9B909A23788" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTI8</accession>
    <name>G4MTI8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Minor allergen Alt a 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714546.1">
        <property type="nucleotide sequence ID" value="XM_003714498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTI8"/>
    <dbReference type="SMR" id="G4MTI8"/>
    <dbReference type="FunCoup" id="G4MTI8">
        <property type="interactions" value="403"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTI8"/>
    <dbReference type="GeneID" id="2679515"/>
    <dbReference type="KEGG" id="mgr:MGG_01569"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01569"/>
    <dbReference type="eggNOG" id="KOG3135">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051402_0_1_1"/>
    <dbReference type="InParanoid" id="G4MTI8"/>
    <dbReference type="OMA" id="KFADGNP"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="PHI-base" id="PHI:6455"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="5"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="204" mass="21820" checksum="05D5A998589E3C6A" modified="2011-12-14" version="1">MAPKIAIVYYSMYGHIKQLAEAEKAGIEKAGGTADLFQIEETLPEEVLSKMGAPAKPTDVKVLSDPSTLEAYDAFLFGIPTRYGNFPGQWKAFIDKTGKQWAAGGFYGKYAGIFISTASQGGGQESTAIAAMSTFAHHGIIYVPLGYTKCFGIQTDLSEARGGSPWGAGTFAGGDGSRQPSEKELELARIQGEEFYNHVSKATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTR4</accession>
    <name>G4MTR4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleolar complex protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_11360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713710.1">
        <property type="nucleotide sequence ID" value="XM_003713662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTR4"/>
    <dbReference type="SMR" id="G4MTR4"/>
    <dbReference type="FunCoup" id="G4MTR4">
        <property type="interactions" value="609"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTR4"/>
    <dbReference type="GeneID" id="5051317"/>
    <dbReference type="KEGG" id="mgr:MGG_11360"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11360"/>
    <dbReference type="eggNOG" id="KOG2154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015945_1_0_1"/>
    <dbReference type="InParanoid" id="G4MTR4"/>
    <dbReference type="OMA" id="YYNNIVT"/>
    <dbReference type="OrthoDB" id="10263185at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="6">
        <location>
            <begin position="315"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA53903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="542" mass="61301" checksum="7DB87E78F4B3A56C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUT0</accession>
    <name>G4MUT0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01679</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase C56 family. HSP31-like subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714667.1">
        <property type="nucleotide sequence ID" value="XM_003714619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUT0"/>
    <dbReference type="SMR" id="G4MUT0"/>
    <dbReference type="FunCoup" id="G4MUT0">
        <property type="interactions" value="62"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUT0"/>
    <dbReference type="GeneID" id="2679356"/>
    <dbReference type="KEGG" id="mgr:MGG_01679"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01679"/>
    <dbReference type="eggNOG" id="ENOG502RZ3Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070319_2_0_1"/>
    <dbReference type="InParanoid" id="G4MUT0"/>
    <dbReference type="OMA" id="GEKTGFW"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03141">
        <property type="entry name" value="GATase1_Hsp31_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF11">
        <property type="entry name" value="GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="6">
        <location>
            <begin position="31"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="231" mass="24996" checksum="A9DABB41791561C8" modified="2011-12-14" version="1">MVKKVLVVLTSASEMKNKNGNAKPTGWFLPEFAHPYDEFAKAGYELTVVSPKGGESKLDPASIEMFKSDPSSTSFLNNQKDLWEKTKKLSDYVDKASEFDAVFYPGGHGPMLDLAVDAESQKLIANFFEAGKPVAAVCHAPIVLADVKLSTGEYLVKGKTVTGFTNKEEEIMQLVDYMPFLLEDKVKASGASFVKADEPWGEKVVVDGKLITGQNPASAKALGEALVKVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV47</accession>
    <name>G4MV47_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713869.1">
        <property type="nucleotide sequence ID" value="XM_003713821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV47"/>
    <dbReference type="GeneID" id="12987269"/>
    <dbReference type="KEGG" id="mgr:MGG_15595"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15595"/>
    <dbReference type="HOGENOM" id="CLU_3050797_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV47"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="54" mass="5808" checksum="20C8974473EF82FE" modified="2011-12-14" version="1">MYLLGTWEGEGIRESRLPEAAAGHVGFLEGPDPGSHPGPDQTEHAPYLQKLVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVI4</accession>
    <name>G4MVI4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Gluconolactonase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10801</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715617.1">
        <property type="nucleotide sequence ID" value="XM_003715569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVI4"/>
    <dbReference type="SMR" id="G4MVI4"/>
    <dbReference type="STRING" id="242507.G4MVI4"/>
    <dbReference type="GeneID" id="2676332"/>
    <dbReference type="KEGG" id="mgr:MGG_10801"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10801"/>
    <dbReference type="eggNOG" id="ENOG502QV6Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036110_0_1_1"/>
    <dbReference type="InParanoid" id="G4MVI4"/>
    <dbReference type="OMA" id="NDRMLRW"/>
    <dbReference type="OrthoDB" id="423498at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051262">
        <property type="entry name" value="SMP-30/CGR1_Lactonase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47572:SF5">
        <property type="entry name" value="BLR2277 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47572">
        <property type="entry name" value="LIPOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="3">
        <location>
            <begin position="45"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605511-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR605511-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA55810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="311" mass="33937" checksum="44D4063509F531E0" modified="2011-12-14" version="1">MNFYPVPPVIKAELCLRIPDDKRCIGQDSEWRGGFARKFQHIFLEGPVYDSDGNLYVVDIPYGRILRIDGSKNVTVSCKWDGEPNGLVGTADGKLLIADYKQGILSFDPADGKVKPHLTRRNLERFKGPNDLILDSRGNLYFTDQGQTGMTDQTGKVYRLSSDGRLDTLVENGASPNGLVLSVDEKFLFVAMTRSNQVWRLPLHDNGTTTKAGVFFQSFGSAGPDGLAVDEEGSLFVCHPSLGSVFVVDASGVPKARIVSGTDGVNLTKCCFGGPEHKTLFITDSLEGNVQKVEWHCRGAVPAPRLNKAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVN8</accession>
    <name>G4MVN8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Threonine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_08923</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713954.1">
        <property type="nucleotide sequence ID" value="XM_003713906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVN8"/>
    <dbReference type="SMR" id="G4MVN8"/>
    <dbReference type="FunCoup" id="G4MVN8">
        <property type="interactions" value="247"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MVN8"/>
    <dbReference type="GeneID" id="2679909"/>
    <dbReference type="KEGG" id="mgr:MGG_08923"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08923"/>
    <dbReference type="eggNOG" id="KOG2616">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015170_1_0_1"/>
    <dbReference type="InParanoid" id="G4MVN8"/>
    <dbReference type="OMA" id="NFERYLY"/>
    <dbReference type="OrthoDB" id="5203861at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01560">
        <property type="entry name" value="Thr-synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000024">
        <property type="entry name" value="Probable threonine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1380.10:FF:000003">
        <property type="entry name" value="THR4p Threonine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="entry name" value="Threonine synthase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051166">
        <property type="entry name" value="Threonine_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690">
        <property type="entry name" value="THREONINE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690:SF1">
        <property type="entry name" value="THREONINE SYNTHASE-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24857">
        <property type="entry name" value="THR4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Threonine synthase N-terminal" evidence="8">
        <location>
            <begin position="20"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="7">
        <location>
            <begin position="116"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA54147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="549" mass="60597" checksum="E383BB119E6AAF05" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVR4</accession>
    <name>G4MVR4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyrimidine 5'-nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_01783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714788.1">
        <property type="nucleotide sequence ID" value="XM_003714740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVR4"/>
    <dbReference type="FunCoup" id="G4MVR4">
        <property type="interactions" value="538"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MVR4"/>
    <dbReference type="GeneID" id="2679221"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01783"/>
    <dbReference type="eggNOG" id="KOG3109">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4MVR4"/>
    <dbReference type="OrthoDB" id="1065058at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.450:FF:000001">
        <property type="entry name" value="SDT1p Pyrimidine nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010237">
        <property type="entry name" value="Pyr-5-nucltdase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052791">
        <property type="entry name" value="SSM1_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01993">
        <property type="entry name" value="Pyr-5-nucltdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438:SF1">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01132">
        <property type="entry name" value="C1.5.3:_5'-Nucleotidase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="34928" checksum="C2BDE633F6A4D0A2" modified="2011-12-14" version="1">MNGQDTTMSLVHLFRQIRPAVNISNTRILKTGVTQKAVFGLSAIRHPYFAYQIHPVAVHWVHDSNMGSNGLSTDGVDRHPTKIFFFDIDNCLYPKSAKVHDRMADLIDKYFAEHLSLSWDEAVRLHKEYYQNYGLAIEGLVRHHQIDPLEYNSKVDDALPLEGIIKPNPQLRKMLEDIDRSKVKLWLFTNAYVNHARRVVRLLEIEDLFDGITYCDYAAQPLVCKPHEDAFANAMRDAGVENVDDCYFVDDNYQNCRKANEIGWHTAHLVEEGVKVPRTPASKHQIRSLEELRNVFPDVFKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVR6</accession>
    <name>G4MVR6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Mediator of RNA polymerase II transcription subunit 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_01784</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mediator complex subunit 21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714789.1">
        <property type="nucleotide sequence ID" value="XM_003714741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVR6"/>
    <dbReference type="SMR" id="G4MVR6"/>
    <dbReference type="FunCoup" id="G4MVR6">
        <property type="interactions" value="261"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MVR6"/>
    <dbReference type="GeneID" id="2679222"/>
    <dbReference type="KEGG" id="mgr:MGG_01784"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01784"/>
    <dbReference type="eggNOG" id="KOG1510">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094271_1_1_1"/>
    <dbReference type="InParanoid" id="G4MVR6"/>
    <dbReference type="OMA" id="LTTYHDH"/>
    <dbReference type="OrthoDB" id="526653at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.10">
        <property type="entry name" value="Mediator complex, subunit Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021384">
        <property type="entry name" value="Mediator_Med21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381:SF0">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381">
        <property type="entry name" value="RNA POLYMERASE II HOLOENZYME COMPONENT SRB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11221">
        <property type="entry name" value="Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="86"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA54982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="144" mass="16566" checksum="15D08B99F27FA213" modified="2011-12-14" version="1">MGDRLTQLQDAVDQLAQQFVACLYYLHKRHDLETLGPDDKIRELKPEDDPKEVDPVPADEFKAGQLELARDLIVKEQQIEMLVSTLPGLENSEEDQERNIQELEEELRVAEAQRQEALRDKQEAQKRLDQVIRSIKRPAAVPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVS7</accession>
    <name>G4MVS7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Required for respiratory growth protein 9, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_15767</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for respiratory activity and maintenance and expression of the mitochondrial genome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRG9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714800.1">
        <property type="nucleotide sequence ID" value="XM_003714752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVS7"/>
    <dbReference type="SMR" id="G4MVS7"/>
    <dbReference type="FunCoup" id="G4MVS7">
        <property type="interactions" value="22"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MVS7"/>
    <dbReference type="GeneID" id="12985412"/>
    <dbReference type="KEGG" id="mgr:MGG_15767"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15767"/>
    <dbReference type="eggNOG" id="ENOG502S7IA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047598_2_0_1"/>
    <dbReference type="InParanoid" id="G4MVS7"/>
    <dbReference type="OrthoDB" id="5578174at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010487">
        <property type="entry name" value="NGRN/Rrg9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13475">
        <property type="entry name" value="NEUGRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13475:SF3">
        <property type="entry name" value="NEUGRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06413">
        <property type="entry name" value="Neugrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="213" mass="25326" checksum="8EB866F49952F741" modified="2011-12-14" version="1">MLQFGPGDTPPQTEETPQERKKRRLETANAKDKKDSKIDKHKGKEADRKKQTRASAEEPKPKKESWMVQKAALEKKFGDQGWRPQKKLSPDAIQGIRALHQQFPDVYTTPALAQRFEISPEAIRRILKSNWTPSAKEEEDRQQRWFKRGKQIWEQKAEQGTKPPKKWREEGVKPNWDAKREFVKRKMEFRRRDMEEEDFPPPRRFNNRPRPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVU3</accession>
    <name>G4MVU3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">TBP-associated factor 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_01805</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714816.1">
        <property type="nucleotide sequence ID" value="XM_003714768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVU3"/>
    <dbReference type="STRING" id="242507.G4MVU3"/>
    <dbReference type="GeneID" id="2679384"/>
    <dbReference type="KEGG" id="mgr:MGG_01805"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01805"/>
    <dbReference type="eggNOG" id="ENOG502S5JC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015147_1_0_1"/>
    <dbReference type="InParanoid" id="G4MVU3"/>
    <dbReference type="OMA" id="KYSWMTG"/>
    <dbReference type="OrthoDB" id="21060at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007900">
        <property type="entry name" value="TAF4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05236">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PRICHEXTENSN"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID component TAF4 C-terminal" evidence="10">
        <location>
            <begin position="534"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="180"/>
            <end position="210"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="439"/>
            <end position="461"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="496"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="554"/>
            <end position="573"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="579"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="51"/>
            <end position="69"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="77"/>
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        <location>
            <begin position="92"/>
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            <begin position="496"/>
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        <location>
            <begin position="593"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006178"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00017306"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025346"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031747"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05236"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA55009.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
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    <sequence length="673" mass="70568" checksum="6A4733FFA5321C59" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2020-04-22" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVZ7</accession>
    <name>CYP1B_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome P450 monooxygenase CYP1</fullName>
            <ecNumber evidence="6">1.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ACE1 cytochalasan biosynthesis cluster protein CYP1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CYP1</name>
        <name type="ORF">MGG_08387</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2008" name="New Phytol." volume="179" first="196" last="208">
            <title>Magnaporthe grisea avirulence gene ACE1 belongs to an infection-specific gene cluster involved in secondary metabolism.</title>
            <authorList>
                <person name="Collemare J."/>
                <person name="Pianfetti M."/>
                <person name="Houlle A.E."/>
                <person name="Morin D."/>
                <person name="Camborde L."/>
                <person name="Gagey M.J."/>
                <person name="Barbisan C."/>
                <person name="Fudal I."/>
                <person name="Lebrun M.H."/>
                <person name="Boehnert H.U."/>
            </authorList>
            <dbReference type="PubMed" id="18433432"/>
            <dbReference type="DOI" id="10.1111/j.1469-8137.2008.02459.x"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>INDUCTION</scope>
        <scope>PATHWAY</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2015" name="Chem. Sci." volume="6" first="4837" last="4845">
            <title>Heterologous expression of the avirulence gene ACE1 from the fungal rice pathogen Magnaporthe oryzae.</title>
            <authorList>
                <person name="Song Z."/>
                <person name="Bakeer W."/>
                <person name="Marshall J.W."/>
                <person name="Yakasai A.A."/>
                <person name="Khalid R.M."/>
                <person name="Collemare J."/>
                <person name="Skellam E."/>
                <person name="Tharreau D."/>
                <person name="Lebrun M.H."/>
                <person name="Lazarus C.M."/>
                <person name="Bailey A.M."/>
                <person name="Simpson T.J."/>
                <person name="Cox R.J."/>
            </authorList>
            <dbReference type="PubMed" id="29142718"/>
            <dbReference type="DOI" id="10.1039/c4sc03707c"/>
        </citation>
        <scope>FUNCTION</scope>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2019" name="Org. Lett." volume="21" first="8756" last="8760">
            <title>Investigating the function of cryptic cytochalasan cytochrome P450 monooxygenases using combinatorial biosynthesis.</title>
            <authorList>
                <person name="Wang C."/>
                <person name="Becker K."/>
                <person name="Pfutze S."/>
                <person name="Kuhnert E."/>
                <person name="Stadler M."/>
                <person name="Cox R.J."/>
                <person name="Skellam E."/>
            </authorList>
            <dbReference type="PubMed" id="31644300"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>PATHWAY</scope>
    </reference>
    <comment type="function">
        <text evidence="4 5 6 10 11">Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of a tyrosine-derived cytochalasan acting as a fungal signal recognized by resistant rice plants and leads to avirulence in Pi33 resistant rice cultivars (PubMed:18433432, PubMed:31644300). The first step in the pathway is catalyzed by the hybrid PKS-NRPS ACE1, assisted by the enoyl reductase RAP1, that are responsible for fusion of the tyrosine precursor and the polyketide backbone (PubMed:29142718). The polyketide synthase module (PKS) of ACE1 is responsible for the synthesis of the polyketide backbone and the downstream nonribosomal peptide synthetase (NRPS) amidates the carboxyl end of the polyketide with the tyrosine precursor (PubMed:29142718). Because ACE1 lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase RAP1 (PubMed:29142718). Reduction by the hydrolyase ORFZ, followed by dehydration and intra-molecular Diels-Alder cyclization by the Diels-Alderase ORF3 then yield the required isoindolone-fused macrocycle (Probable). A number of oxidative steps catalyzed by the tailoring enzymes identified within the cluster, including cytochrome P450 monooxygenases CYP1 to CYP4, the FAD-linked oxidoreductase OXR2 and the short-chain dehydrogenase/reductase OXR1, are further required to afford the final cytochalasans that confer avirulence and which have still to be identified (Probable). The monooxygenase CYP1 has been shown to be a site-selective C-18 hydroxylase whereas the function of CYP3 is the site-selective epoxidation of the C-6/C-7 olefin that is present in some intermediate compounds (PubMed:31644300). Finally, SYN2 and RAP2 are not required for avirulence in Pi33 resistant rice cultivars (PubMed:18433432).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 10">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="4">Expressed exclusively during fungal penetration of host leaves, the time point at which plant defense reactions are triggered.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="6"/>
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        <property type="protein sequence ID" value="EHA55865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003715624.1"/>
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        <property type="glycosylation" value="3 sites, No reported glycans"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_08387T0">
        <property type="protein sequence ID" value="MGG_08387T0"/>
        <property type="gene ID" value="MGG_08387"/>
    </dbReference>
    <dbReference type="GeneID" id="2678617"/>
    <dbReference type="KEGG" id="mgr:MGG_08387"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08387"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_2_1"/>
    <dbReference type="InParanoid" id="G4MVZ7"/>
    <dbReference type="OMA" id="NRFKFAN"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF6">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AN1598-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0349">Heme</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0503">Monooxygenase</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000449436" description="Cytochrome P450 monooxygenase CYP1">
        <location>
            <begin position="1"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
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        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="367"/>
        </location>
    </feature>
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        <location>
            <position position="517"/>
        </location>
    </feature>
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        <source>
            <dbReference type="UniProtKB" id="P04798"/>
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        <source>
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            <dbReference type="PubMed" id="18433432"/>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="PubMed" id="18433432"/>
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        <source>
            <dbReference type="PubMed" id="29142718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA55865.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="543" mass="61789" checksum="32421E8AD25CAAA7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW34</accession>
    <name>G4MW34_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA54187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003713994.1">
        <property type="nucleotide sequence ID" value="XM_003713946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW34"/>
    <dbReference type="GeneID" id="12987352"/>
    <dbReference type="KEGG" id="mgr:MGG_15620"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15620"/>
    <dbReference type="HOGENOM" id="CLU_2543012_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW34"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="83" mass="8770" checksum="BD5FFEB2C42BD730" modified="2011-12-14" version="1">MKFSIVLFHFTAAAYGIALSAGGVIMPHLISRATDPCASQAARNSKSCCQKTPVAVQIEGQAECAQRGKEFVGCDKDAVVHCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW54</accession>
    <name>G4MW54_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15775</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714821.1">
        <property type="nucleotide sequence ID" value="XM_003714773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW54"/>
    <dbReference type="GeneID" id="12985421"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15775"/>
    <dbReference type="HOGENOM" id="CLU_110338_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW54"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="218" mass="23588" checksum="FB4FF161A9B52EF0" modified="2011-12-14" version="1">MLSPASKTSIMSVMPASKAMKPSKRNNIEESPGKQDADAVQPTVEYDLDGNTVTSLHQEIDTCGSPTRSSRESSEKVQPTTPESNPCGREINNLNSEELPTLSSDTPEESDGHVEALALSSDPSQMPPRAAAAAEDRELIWARPGLGLSDPFVQTDNMTATLGKEDNLDESVYTLLHSYVLKSHNPDLWLAMANSMARRGKLLEDLSSTPEGCRSLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWU2</accession>
    <name>G4MWU2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15949</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715753.1">
        <property type="nucleotide sequence ID" value="XM_003715705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWU2"/>
    <dbReference type="GeneID" id="12986769"/>
    <dbReference type="KEGG" id="mgr:MGG_15949"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15949"/>
    <dbReference type="HOGENOM" id="CLU_2622487_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWU2"/>
    <dbReference type="OrthoDB" id="10406247at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="78" mass="8455" checksum="C7122566189C4C63" modified="2011-12-14" version="1">MFSLEQKRSIIFRFCRFRSIIRVAALGSNYPPAHEGILAVVRGAQSCMHALFKAPPCDAMDAGSKPVSLFGKAPGLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWW9</accession>
    <name>G4MWW9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Autophagy-related protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714068.1">
        <property type="nucleotide sequence ID" value="XM_003714020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWW9"/>
    <dbReference type="GeneID" id="2679785"/>
    <dbReference type="KEGG" id="mgr:MGG_11280"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11280"/>
    <dbReference type="HOGENOM" id="CLU_963366_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWW9"/>
    <dbReference type="OrthoDB" id="5243415at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465428" description="Autophagy-related protein 27" evidence="2">
        <location>
            <begin position="32"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="30085" checksum="344F07821BC10BA4" modified="2011-12-14" version="1">MRPRTSRHHLYNGYRLAYLILLSYSCKVTLASPVSGRPRCVSPTVSQPTPIASGLVILGYHDGDIGRPLQVPYGKVVVTDSDRMMWGYCGEVSVGDETCRLAGASSESHSSICTTATWTRRDGAAFASLGCGPTATTAHILEEPLYRVFIGQETLFPSGETARAGRSESGLDAVTVAVPVEIGYEAAQATETGTPESGVGSHDSVEVPATATTSAAAESPQVGGLAPGQVGGIVVGSIAGAALLAFGTLYIAWRHLLSRFSMAMGSIYMTLYHPRPAPASTSQAHAAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXI9</accession>
    <name>G4MXI9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714127.1">
        <property type="nucleotide sequence ID" value="XM_003714079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXI9"/>
    <dbReference type="GeneID" id="12984599"/>
    <dbReference type="KEGG" id="mgr:MGG_15648"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15648"/>
    <dbReference type="HOGENOM" id="CLU_1695839_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXI9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="155" mass="16533" checksum="CF7D6B70C7DC0626" modified="2011-12-14" version="1">MEQASKTEAKSLKANTGFGDPSYGMTEGICEPDKGIVHLHDLVPRGSRVDDSMLIPRFPSISPAGGNGALRLPREPGRRPLPRKKCEFCICYFSAVGGVGDGSGVNKMAQSYNGISQETYAGRPCLALTHAFHGTREAPGAVKQMHVRPGGTILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXM6</accession>
    <name>G4MXM6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714164.1">
        <property type="nucleotide sequence ID" value="XM_003714116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXM6"/>
    <dbReference type="STRING" id="242507.G4MXM6"/>
    <dbReference type="GeneID" id="5051046"/>
    <dbReference type="KEGG" id="mgr:MGG_14774"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14774"/>
    <dbReference type="eggNOG" id="ENOG502S7E3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103432_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXM6"/>
    <dbReference type="OMA" id="AFYGYAM"/>
    <dbReference type="OrthoDB" id="2550114at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39605">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39605:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="169" mass="17717" checksum="8DFD8D7DAF3C97DC" modified="2011-12-14" version="1">MEAISAYSLATCAWLGAQAFPMLLTPGFVNSMLVEGYEPASSVEIYTLRHLGLAQLALSLLSLALSGVLPLAPAASADDSISPYADAAVLLTALYHAANAFHSWARWGATGGSAAYGLGFVGSGVLAAFGLWCLMFAGDKGRISKRTGADKRTSGFPFRNVEADKRKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYQ0</accession>
    <name>G4MYQ0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15823</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715086.1">
        <property type="nucleotide sequence ID" value="XM_003715038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYQ0"/>
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    <dbReference type="HOGENOM" id="CLU_1825669_0_0_1"/>
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        <property type="component" value="Chromosome 2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="141" mass="15775" checksum="A94E147C474DF253" modified="2011-12-14" version="1">MVTKFNSTEKARPKTNISNQVDFRANVHSDFARLAYDSPYLVLGPSWSIYIKTRLLDLRPAKPMNTRRQSLLTVLTYGNTLAASITTSRISRLYSSAANPAVPGCPTQAHRGKYARQPHGHVCMLRNMPAGTDIELMARRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZX0</accession>
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            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711221.1">
        <property type="nucleotide sequence ID" value="XM_003711173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZX0"/>
    <dbReference type="STRING" id="242507.G4MZX0"/>
    <dbReference type="GeneID" id="2680101"/>
    <dbReference type="KEGG" id="mgr:MGG_09114"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09114"/>
    <dbReference type="eggNOG" id="ENOG502S0VB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068952_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZX0"/>
    <dbReference type="OMA" id="GCFLQFQ"/>
    <dbReference type="OrthoDB" id="3926209at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF3">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
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    </dbReference>
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        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="66"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="285" mass="31566" checksum="11DAFDCB76FFC0E8" modified="2011-12-14" version="1">MADNAPADSIVEESPAPSAPAGDVEMTESASGAVEGDESALPYVGEDGPEEPVPARVPFVDYLSSPVVTLMVGSADNSDTQTILTAHQALLTQSPYFATLCAEFEDGTDRHIDLSSEDVDAVGCFLEYLYTGDYFPRKIPGQRQLDQDPSLPKVDDSGDQLLKHARVYTLAEKFQMPALRHLASSKIHCVNSTAKGEIAYARYVYQYIPRDDSHIRAPIVTFWAQRSHTLRAEAEDEFRSLCLEFPQFGYDVLTRVLDEKLKREQVSKMHPSTASGRKRPRHSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="4">Hydrophobin</fullName>
        </recommendedName>
    </protein>
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    <organism evidence="2 3">
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        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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            <taxon>Pyricularia</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003711248.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="2683331"/>
    <dbReference type="KEGG" id="mgr:MGG_07411"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07411"/>
    <dbReference type="eggNOG" id="ENOG502RMJA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2346803_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0Q6"/>
    <dbReference type="OMA" id="CIGAHIM"/>
    <dbReference type="OrthoDB" id="4597489at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465798" description="Hydrophobin" evidence="1">
        <location>
            <begin position="21"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="10772" checksum="6F266C780E4B0599" modified="2011-12-14" version="1">MLYKLAAVVLASSFVSTASAAFNFYCPGVNATGFYPSCCRGITGQVGVDCFSAHLIGGLPNFECNIGPPNNQRGCCQSINYTNPNTGYRLSLCTDTTAYPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N121</accession>
    <name>G4N121_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_07787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713004.1">
        <property type="nucleotide sequence ID" value="XM_003712956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N121"/>
    <dbReference type="GeneID" id="2683714"/>
    <dbReference type="KEGG" id="mgr:MGG_07787"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07787"/>
    <dbReference type="eggNOG" id="ENOG502RSG7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031217_0_0_1"/>
    <dbReference type="InParanoid" id="G4N121"/>
    <dbReference type="OMA" id="KFKCKNM"/>
    <dbReference type="OrthoDB" id="2099887at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027589">
        <property type="entry name" value="Choice_anch_B"/>
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        <property type="entry name" value="choice_anch_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38787:SF3">
        <property type="entry name" value="REGULATORY P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="559" mass="62245" checksum="FDEA8B04BECB2CF8" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1M7</accession>
    <name>G4N1M7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">N-terminal acetyltransferase A complex catalytic subunit ard1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_07496</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA51599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711406.1">
        <property type="nucleotide sequence ID" value="XM_003711358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1M7"/>
    <dbReference type="SMR" id="G4N1M7"/>
    <dbReference type="FunCoup" id="G4N1M7">
        <property type="interactions" value="774"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N1M7"/>
    <dbReference type="GeneID" id="2683416"/>
    <dbReference type="KEGG" id="mgr:MGG_07496"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07496"/>
    <dbReference type="eggNOG" id="KOG3235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_7_0_1"/>
    <dbReference type="InParanoid" id="G4N1M7"/>
    <dbReference type="OMA" id="LPENYFM"/>
    <dbReference type="OrthoDB" id="25586at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
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    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990190">
        <property type="term" value="F:protein-N-terminal-glutamate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000085">
        <property type="entry name" value="Putative N-acetyltransferase complex ARD1 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045047">
        <property type="entry name" value="Ard1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091:SF4">
        <property type="entry name" value="N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="170"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA51599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="230" mass="26196" checksum="17FF25705071C6A1" modified="2011-12-14" version="1">MDIRVIRSSDIPLIQHANLENLPENYFLKYYLYHALSWPQLSYVAVDVSRPKKTPYDYPKIVGYVLAKMEEDPSDGIPHGHITSLSVMRTHRRLGIAEKLMRQSQQAMVETFGARYVSLHVRVSNQAAIHLYRDTLGFKNEKTENKYYADGEDAYCMKLDLDFIRDQLREETEEEGDGEAQDEGEAVGDVGKDPKTAKKGKAGEDKDKMRKVKVGRALGVGELVERVESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1V6</accession>
    <name>G4N1V6_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712278.1">
        <property type="nucleotide sequence ID" value="XM_003712230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1V6"/>
    <dbReference type="GeneID" id="12984960"/>
    <dbReference type="KEGG" id="mgr:MGG_16805"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16805"/>
    <dbReference type="eggNOG" id="ENOG502R5R5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_449079_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1V6"/>
    <dbReference type="OrthoDB" id="10639561at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="617" mass="67418" checksum="7B43D8C0442A61AE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1W3</accession>
    <name>G4N1W3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_09467</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712285.1">
        <property type="nucleotide sequence ID" value="XM_003712237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1W3"/>
    <dbReference type="GeneID" id="2680510"/>
    <dbReference type="KEGG" id="mgr:MGG_09467"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09467"/>
    <dbReference type="eggNOG" id="ENOG502RUUF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019101_1_0_1"/>
    <dbReference type="InParanoid" id="G4N1W3"/>
    <dbReference type="OMA" id="IWGTNNM"/>
    <dbReference type="OrthoDB" id="3903189at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF166">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="3"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="241"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA52478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="327" mass="36818" checksum="B78DE4A3E07120B0" modified="2011-12-14" version="1">MNLGDWLSIAAVVCIVIRLVMVHFILTLGTSNVSEEFRRLHQFTPQEIAERETGSKLAIANRVFYNSYLWLQKLVLLDVYRRLYQNLRFEKIVVTSILVIFFGTYAACQISTFVECTPIELYWQLVPDPGSCVKAQLQLIVVGVTNIVTDFILLILPLPIVFQMLSATWQRKVQLVALFMLGLFVIIITAVRLPINHDQADSQLSRTTWASVELVVAAFVVNAPTLYGLWNKRRQESKLTASSHVTGPGMYGLGTSRTHRKLRDEESSGGDSYEMDIPRGSSGSQDPKNGITLTREVIVHTEEVPRAEQGNIRGIQPNPQAAWDTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N226</accession>
    <name>G4N226_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar aminopeptidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07536</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711449.1">
        <property type="nucleotide sequence ID" value="XM_003711401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N226"/>
    <dbReference type="SMR" id="G4N226"/>
    <dbReference type="FunCoup" id="G4N226">
        <property type="interactions" value="190"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N226"/>
    <dbReference type="GeneID" id="2683456"/>
    <dbReference type="KEGG" id="mgr:MGG_07536"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07536"/>
    <dbReference type="eggNOG" id="KOG2596">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019532_3_0_1"/>
    <dbReference type="InParanoid" id="G4N226"/>
    <dbReference type="OMA" id="DWPIAKI"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF4">
        <property type="entry name" value="VACUOLAR AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA51642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="621" mass="66052" checksum="B74EB583FDC3B81D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2C5</accession>
    <name>G4N2C5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713137.1">
        <property type="nucleotide sequence ID" value="XM_003713089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2C5"/>
    <dbReference type="GeneID" id="12986061"/>
    <dbReference type="KEGG" id="mgr:MGG_16959"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16959"/>
    <dbReference type="HOGENOM" id="CLU_2622489_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2C5"/>
    <dbReference type="OrthoDB" id="10455475at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="78" mass="8229" checksum="2BFB0270875FC255" modified="2011-12-14" version="1">MPSESSSQKDSRTSAQRGSKSSNSSTKAQRGSASGSQHGQTQETGGSSSQDHSGAKVPVKVFYSEQDFAHIGAQFYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2G4</accession>
    <name>G4N2G4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713176.1">
        <property type="nucleotide sequence ID" value="XM_003713128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2G4"/>
    <dbReference type="GeneID" id="12986073"/>
    <dbReference type="KEGG" id="mgr:MGG_16968"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16968"/>
    <dbReference type="HOGENOM" id="CLU_2740524_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2G4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="71" mass="7995" checksum="5977BC928F738C86" modified="2011-12-14" version="1">MYGVSGVPHCRRREAIATNGEKFQRMVITLYCDHPKEPSARTSRSTSNPQMMQEQATNLMVEAKAVPLSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2X8</accession>
    <name>G4N2X8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_15267</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713234.1">
        <property type="nucleotide sequence ID" value="XM_003713186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2X8"/>
    <dbReference type="SMR" id="G4N2X8"/>
    <dbReference type="GeneID" id="12986131"/>
    <dbReference type="KEGG" id="mgr:MGG_15267"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15267"/>
    <dbReference type="eggNOG" id="ENOG502SFDE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063084_7_1_1"/>
    <dbReference type="InParanoid" id="G4N2X8"/>
    <dbReference type="OMA" id="CATDFAC"/>
    <dbReference type="OrthoDB" id="3767534at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF2">
        <property type="entry name" value="GPI ANCHORED CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G10580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465922" description="CFEM domain-containing protein" evidence="16">
        <location>
            <begin position="18"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="17">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA53427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="92" mass="9247" checksum="41D781BEE24F21D8" modified="2011-12-14" version="1">MQIKNVLIAAFAATATAQDISKLPFCALSCFISNSGVSGCASVLDFACSCASAPYFAAVTTCATNSCSAADQATTRAWAVATCQSVGVPLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4N311</accession>
    <name>G4N311_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711577.1">
        <property type="nucleotide sequence ID" value="XM_003711529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N311"/>
    <dbReference type="GeneID" id="12984143"/>
    <dbReference type="KEGG" id="mgr:MGG_16672"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16672"/>
    <dbReference type="HOGENOM" id="CLU_2590203_0_0_1"/>
    <dbReference type="InParanoid" id="G4N311"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="80" mass="8413" checksum="3D4E2A6C1CD92646" modified="2011-12-14" version="1">MDSWNLAIAMKIAAPPRTSSAQACVDVCVVMAARQDHLRQGIAKRGQANGLAGVRRSKGAGNGVLMKKPKTKLATAIQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3A9</accession>
    <name>G4N3A9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713261.1">
        <property type="nucleotide sequence ID" value="XM_003713213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3A9"/>
    <dbReference type="GeneID" id="12986159"/>
    <dbReference type="KEGG" id="mgr:MGG_16992"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16992"/>
    <dbReference type="eggNOG" id="ENOG502SNSN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1294631_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3A9"/>
    <dbReference type="OrthoDB" id="3549294at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="213" mass="24559" checksum="5401BAF2C2B1E26D" modified="2011-12-14" version="1">MLPWTGSPLSFIDTPGSGAYVREDGRVLREDVWRLRHQNWRAEPDGLVFRNFPLCPWPPFGSIHVNELELAVRSSTACERHRRVYVRWTWRFGDKTVTEETQKQQKKHHTTASDSQGPDSPPRKPTDDLRDTLEYFGSSEASKSAVRDIFRWSMDELEPSGKEVYSHGWVELIPPDEESDFEDGASGGSEKDVDFTDPSHQGRIEQWINTLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4Z6</accession>
    <name>G4N4Z6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epoxide hydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05175</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712714.1">
        <property type="nucleotide sequence ID" value="XM_003712666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4Z6"/>
    <dbReference type="SMR" id="G4N4Z6"/>
    <dbReference type="STRING" id="242507.G4N4Z6"/>
    <dbReference type="ESTHER" id="mago7-a4qt55">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="GeneID" id="2675593"/>
    <dbReference type="KEGG" id="mgr:MGG_05175"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05175"/>
    <dbReference type="eggNOG" id="KOG4178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_5_1"/>
    <dbReference type="InParanoid" id="G4N4Z6"/>
    <dbReference type="OMA" id="YQIPMLV"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="44"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="366" mass="40531" checksum="C2B524F63D0FF879" modified="2011-12-14" version="1">MASANLAKLAPNDPRVEHKDVQVNGRTYHYMLARPPAGAEPKATILLVHGFPDLGLGWRHQVPVLAAQGFQVVVPDMLGYGGTDAPQDVEPYRHKSIIDDLLALLDSQDLIVPLGPSRERRVVLGGHDWGGQIVWRFTEWYPERIAATFSVCTPFFPPMPSFIDLSTLTQIIPSFKYQLQFASEEVVDRTTGPDGKPSRAVIRDFLNALWGGAGTIQAADAPKGFTAAEGVNFSIIKDLPQAQLMSVEELDFYADQYSRNGMRGPTNWYRLRKLNFEDELTLIERRQKQAEETGDEPKIKTPSLFISASRDVALPPAMSANMDMCFESLTRGHVDASHWALVEAASEVNATILSFLDNVIKPKASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5C2</accession>
    <name>G4N5C2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Magnesium and cobalt transporter CorA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_05233</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712786.1">
        <property type="nucleotide sequence ID" value="XM_003712738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5C2"/>
    <dbReference type="SMR" id="G4N5C2"/>
    <dbReference type="STRING" id="242507.G4N5C2"/>
    <dbReference type="GeneID" id="2675710"/>
    <dbReference type="KEGG" id="mgr:MGG_05233"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05233"/>
    <dbReference type="eggNOG" id="ENOG502RY63">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015119_2_0_1"/>
    <dbReference type="InParanoid" id="G4N5C2"/>
    <dbReference type="OMA" id="NYGHIRQ"/>
    <dbReference type="OrthoDB" id="165352at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="245"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="632" mass="71139" checksum="58E96C278027C146" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5Q5</accession>
    <name>G4N5Q5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar-sorting protein SNF8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_05291</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SNF8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712852.1">
        <property type="nucleotide sequence ID" value="XM_003712804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5Q5"/>
    <dbReference type="SMR" id="G4N5Q5"/>
    <dbReference type="FunCoup" id="G4N5Q5">
        <property type="interactions" value="648"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5Q5"/>
    <dbReference type="GeneID" id="2675375"/>
    <dbReference type="KEGG" id="mgr:MGG_05291"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05291"/>
    <dbReference type="eggNOG" id="KOG3341">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070147_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5Q5"/>
    <dbReference type="OMA" id="QIVEVCM"/>
    <dbReference type="OrthoDB" id="283883at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000085">
        <property type="entry name" value="Vacuolar-sorting protein SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000397">
        <property type="entry name" value="Vacuolar-sorting protein SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016689">
        <property type="entry name" value="ESCRT-2_cplx_Snf8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806">
        <property type="entry name" value="EAP30 SUBUNIT OF ELL COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806:SF0">
        <property type="entry name" value="VACUOLAR-SORTING PROTEIN SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017215">
        <property type="entry name" value="ESCRT2_Vps22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR017215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="258" mass="28290" checksum="77F3AAB4D6DFC1D4" modified="2011-12-14" version="1">MSRKGVGLAAFDRSRLTSAQYATHGSALRTSNAQALQTQLEVFRSLLQQFAQTHAKDIRSDPAFRAQFARMCAAIGIDPLASSSSGKSGGGSVWGQLLGRSVNDFYFGLAVRVVEVCGQTRGENGGLLEVRKVREMIQRSRSEGSAEVTEDDIFRAVGTLKPLGSAYSIIKVGSKPYIRSIPKELNTDQSAVLEAVQVLGYVSISMLMANLRWTRPRSQTAIEDLLSEGMLWVDKQSEEWEYWSPSYMLGPQAESNGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5W6</accession>
    <name>G4N5W6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Proline-specific permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_08548</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716061.1">
        <property type="nucleotide sequence ID" value="XM_003716013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5W6"/>
    <dbReference type="SMR" id="G4N5W6"/>
    <dbReference type="GeneID" id="2678680"/>
    <dbReference type="KEGG" id="mgr:MGG_08548"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08548"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="InParanoid" id="G4N5W6"/>
    <dbReference type="OMA" id="WKVFIQA"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF21">
        <property type="entry name" value="GENERAL AMINO ACID PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="492"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="526"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="84"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA49742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="587" mass="64656" checksum="DCA2F9A701492380" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7T7</accession>
    <name>G4N7T7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06364</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717210.1">
        <property type="nucleotide sequence ID" value="XM_003717162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7T7"/>
    <dbReference type="GeneID" id="2684519"/>
    <dbReference type="KEGG" id="mgr:MGG_06364"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06364"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_441501_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7T7"/>
    <dbReference type="OMA" id="CEVERGP"/>
    <dbReference type="OrthoDB" id="9368434at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF139">
        <property type="entry name" value="PAIR-RULE PROTEIN ODD-PAIRED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="78"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="254"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="469"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="513"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="498"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="619" mass="68552" checksum="021E84C23F2E311A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4N811</accession>
    <name>G4N811_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent DNA helicase CHL1</fullName>
            <ecNumber evidence="18">5.6.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-dependent DNA helicase chl1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Chromosome loss protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19 20">DNA 5'-3' helicase CHL1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">MGG_13542</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="27">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="18"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716432.1">
        <property type="nucleotide sequence ID" value="XM_003716384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N811"/>
    <dbReference type="FunCoup" id="G4N811">
        <property type="interactions" value="980"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N811"/>
    <dbReference type="GeneID" id="5051690"/>
    <dbReference type="KEGG" id="mgr:MGG_13542"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13542"/>
    <dbReference type="eggNOG" id="KOG1133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006515_2_0_1"/>
    <dbReference type="InParanoid" id="G4N811"/>
    <dbReference type="OMA" id="QTHQFRD"/>
    <dbReference type="OrthoDB" id="267079at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034085">
        <property type="term" value="P:establishment of sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002774">
        <property type="entry name" value="ATP-dependent DNA helicase chl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF41">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="24">
        <location>
            <begin position="6"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="115"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="795"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="797"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00044998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00045008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00045702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="EHA50113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="921" mass="101996" checksum="3488A31AB8C2A537" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8A6</accession>
    <name>G4N8A6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-L-rhamnosidase six-hairpin glycosidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_03455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716472.1">
        <property type="nucleotide sequence ID" value="XM_003716424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8A6"/>
    <dbReference type="GeneID" id="2676871"/>
    <dbReference type="KEGG" id="mgr:MGG_03455"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03455"/>
    <dbReference type="eggNOG" id="ENOG502RKM7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027955_0_0_1"/>
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    <dbReference type="OMA" id="GRENAVM"/>
    <dbReference type="OrthoDB" id="5229093at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="646" mass="72446" checksum="0D1DA85441E9B2D5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8Y9</accession>
    <name>G4N8Y9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">superoxide dismutase</fullName>
            <ecNumber evidence="4">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03350</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716602.1">
        <property type="nucleotide sequence ID" value="XM_003716554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8Y9"/>
    <dbReference type="SMR" id="G4N8Y9"/>
    <dbReference type="STRING" id="242507.G4N8Y9"/>
    <dbReference type="GeneID" id="2676482"/>
    <dbReference type="KEGG" id="mgr:MGG_03350"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03350"/>
    <dbReference type="eggNOG" id="ENOG502S5NX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1138183_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8Y9"/>
    <dbReference type="OMA" id="ACANITQ"/>
    <dbReference type="OrthoDB" id="159229at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.200:FF:000007">
        <property type="entry name" value="Cell surface Cu-only superoxide dismutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053257">
        <property type="entry name" value="Cu-only_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20910">
        <property type="entry name" value="AGAP001623-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20910:SF1">
        <property type="entry name" value="SUPEROXIDE DISMUTASE COPPER_ZINC BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466715" description="superoxide dismutase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="244" mass="25833" checksum="B1AF94C939458CC4" modified="2011-12-14" version="1">MVLHSHLARSAALLLVACGLGAAETADSAAGSAPGASTGAADIPNVTGKLGDAASITNNPPGRYRAGWMATPSNPFSGSIEAISSPNGKGVIFLVNLENLPAQGGPFSYHIHDQPVPDDGNCNKTLAHLDPYQRGQKPDCDAGEPQTCEVGDLSGKHGKIEGTNVQDRMFHDMYTSLAEGIGAFVGNRSVVIHFANTTRFACSNFVAVYPDRHKADEKHRPMNKDNMAPHARRMLSFMKALRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4N931</accession>
    <name>G4N931_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10 13">Catalase</fullName>
            <ecNumber evidence="3 10 13">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_10061</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 13">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10 13"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717445.1">
        <property type="nucleotide sequence ID" value="XM_003717397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N931"/>
    <dbReference type="SMR" id="G4N931"/>
    <dbReference type="FunCoup" id="G4N931">
        <property type="interactions" value="1065"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N931"/>
    <dbReference type="GeneID" id="2681672"/>
    <dbReference type="KEGG" id="mgr:MGG_10061"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10061"/>
    <dbReference type="eggNOG" id="KOG0047">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010645_3_0_1"/>
    <dbReference type="InParanoid" id="G4N931"/>
    <dbReference type="OMA" id="WQMSDRA"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000003">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821:SF1">
        <property type="entry name" value="CATALASE-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 13" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 13" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="16">
        <location>
            <begin position="43"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA51126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="743" mass="82756" checksum="CE2182DA452B33DD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N973</accession>
    <name>G4N973_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA polymerase II-associated protein RBA50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_03321</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RPAP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716636.1">
        <property type="nucleotide sequence ID" value="XM_003716588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N973"/>
    <dbReference type="FunCoup" id="G4N973">
        <property type="interactions" value="148"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N973"/>
    <dbReference type="GeneID" id="2676864"/>
    <dbReference type="KEGG" id="mgr:MGG_03321"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03321"/>
    <dbReference type="eggNOG" id="KOG1894">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031074_1_0_1"/>
    <dbReference type="InParanoid" id="G4N973"/>
    <dbReference type="OMA" id="DQESPYY"/>
    <dbReference type="OrthoDB" id="348201at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039913">
        <property type="entry name" value="RPAP1/Rba50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013929">
        <property type="entry name" value="RPAP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013930">
        <property type="entry name" value="RPAP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483:SF18">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08620">
        <property type="entry name" value="RPAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08621">
        <property type="entry name" value="RPAP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RPAP1 N-terminal" evidence="4">
        <location>
            <begin position="92"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="RPAP1 C-terminal" evidence="3">
        <location>
            <begin position="297"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA50317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="46924" checksum="B7B7F58B478D6A9F" modified="2011-12-14" version="1">METTLRVLDVREKETGSQVRPPAFPTPKPNGFPEHKKRTRVSAFKRQKQQEQSGATPNSGAGTSQSSFPSGSPSEDGPNNDQDRPHFDSERRRIDKENRERLAAMSAEDIAEAQSEILQLDPSLIQMLLRRANLDEKPAGPDPFAGDNSTETAASKSDATGQVPPKSTSCSKPEDESNGDPKGASAENEAPAPKKKTVSFAPTVEDDEPDAEEPAPRPEIPDQVLPTNTTHFPHPANPPDLDPADPNFLETLHSKYFPNLPADPARLAWMAPVPTEDSPADRESPYYPGQTSLAVSQLRFDFQGRLLPPRVSRKIPVSLGLHHHGEAPEAAGYTVGELSRLARSAVPAQRCIAFQTLGRILFRLGKGEWGVGEGTMGMGIFRCVSEGRVLDSLKEAAAVEEGVGHRSSRAYAIEALWLYEKGGWTKSFKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9I9</accession>
    <name>G4N9I9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03266</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716700.1">
        <property type="nucleotide sequence ID" value="XM_003716652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9I9"/>
    <dbReference type="SMR" id="G4N9I9"/>
    <dbReference type="FunCoup" id="G4N9I9">
        <property type="interactions" value="645"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9I9"/>
    <dbReference type="GeneID" id="2676855"/>
    <dbReference type="KEGG" id="mgr:MGG_03266"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03266"/>
    <dbReference type="eggNOG" id="KOG4131">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037423_0_1_1"/>
    <dbReference type="InParanoid" id="G4N9I9"/>
    <dbReference type="OMA" id="NFDKTHL"/>
    <dbReference type="OrthoDB" id="3345469at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1390.30:FF:000001">
        <property type="entry name" value="GTP cyclohydrolase 1 type 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.30">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="NGG1 INTERACTING FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799:SF13">
        <property type="entry name" value="NIF3-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="DUF34_NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602678-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="389" mass="42319" checksum="19E61F17CB39CE9B" modified="2011-12-14" version="1">MHNRLTTLVYFFFFFIFFFKYLSFLHRMLVSTRPAGPLRRLPLCLSLASKPVHCSPCSLRQASIHRGPTLVPTQRRSFIIPSNNMDLKSSSFTNAVVSAMRSLYPEELADRAWDNVGLLLENTEGPGLAPVVLLTNDVTGAVVDEAIAKNASVIVSYHPPIFRGLKSITLKDPQQQLLLQLVKHNIAVYSPHTAVDATPGGLNDWLADLVSAAANDFPHVKVERTNAKPVTSAIPAGFEGAGYGRVCKFSEPIPWPRVVHAVAQKLGQRYVSLATPRGFPKGMPRGDDASTPTVTSVAVCAGSGADVLGGCGADMLITGEMSHHAALHATMRGQMVMTVFHSNSERRFLRDVMQGKLSEAVRAHFSQTASVLVSEADSDPFEVWDLNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9V5</accession>
    <name>G4N9V5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ARS binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
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                <person name="Abouelleil A."/>
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                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
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                <person name="Gearin G."/>
                <person name="Gellesch M."/>
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                <person name="Nusbaum C."/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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            <end position="409"/>
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            <end position="596"/>
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        <source>
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        <source>
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        <source>
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        </source>
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        <source>
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        <source>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
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        <property type="entry name" value="Zn2Cys6_DnaBD"/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
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                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
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                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA48865.1"/>
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        <source>
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        <source>
            <dbReference type="EMBL" id="EHA48865.1"/>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBE0</accession>
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            <fullName evidence="6">Uncharacterized protein</fullName>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
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            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
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                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
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                <person name="Ma L.J."/>
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                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
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                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Shenoy N."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717774.1">
        <property type="nucleotide sequence ID" value="XM_003717726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBY8"/>
    <dbReference type="SMR" id="G4NBY8"/>
    <dbReference type="STRING" id="242507.G4NBY8"/>
    <dbReference type="GeneID" id="2674105"/>
    <dbReference type="KEGG" id="mgr:MGG_01149"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01149"/>
    <dbReference type="eggNOG" id="ENOG502R8TR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1759180_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBY8"/>
    <dbReference type="OMA" id="INCIVDG"/>
    <dbReference type="OrthoDB" id="5225279at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00747">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="9" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466424" description="CFEM domain-containing protein" evidence="10">
        <location>
            <begin position="17"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="11">
        <location>
            <begin position="7"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA48190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="148" mass="14809" checksum="C4FDC52AC8222554" modified="2011-12-14" version="1">MQLLFALLMAAVLVAAQSGSYGSNIDGLISQVPQCAFNCLAEAAESSSCGLTDIRCMCGRISLVSGTSSTCLSKACSADQLATLSSTISKVCADVGAPDPAAAKTATSNDTVPAASAVPTPSQTAVATRLKLQMATVAMFAALSVNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCB1</accession>
    <name>G4NCB1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Conidial yellow pigment biosynthesis polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00428</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718644.1">
        <property type="nucleotide sequence ID" value="XM_003718596.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NCB1"/>
    <dbReference type="STRING" id="242507.G4NCB1"/>
    <dbReference type="GeneID" id="2674910"/>
    <dbReference type="KEGG" id="mgr:MGG_00428"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00428"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_6_0_1"/>
    <dbReference type="InParanoid" id="G4NCB1"/>
    <dbReference type="OMA" id="NDWGETN"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF40">
        <property type="entry name" value="NORSOLORINIC ACID SYNTHASE STCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="7">
        <location>
            <begin position="411"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="8">
        <location>
            <begin position="1367"/>
            <end position="1688"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1754"/>
            <end position="1832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1367"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="4">
        <location>
            <begin position="1534"/>
            <end position="1688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="4">
        <location>
            <position position="1401"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="4">
        <location>
            <position position="1599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="2173" mass="234678" checksum="47139EA130F80994" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCG3</accession>
    <name>G4NCG3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717844.1">
        <property type="nucleotide sequence ID" value="XM_003717796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCG3"/>
    <dbReference type="GeneID" id="5051306"/>
    <dbReference type="KEGG" id="mgr:MGG_14637"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14637"/>
    <dbReference type="eggNOG" id="ENOG502R1F4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012946_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCG3"/>
    <dbReference type="OMA" id="SAAIVMW"/>
    <dbReference type="OrthoDB" id="4021778at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF15">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="499" mass="55524" checksum="38149AC88A9224E6" modified="2011-12-14" version="1">MAQNTSSGRRIPAVAVAAAKHPKWDHAIPPKLRPLVRAFLLGYGSSVAPRVLTLLLQRLSRRYKRPENTTARQPLQPFFPALFHILRTGFDPQRFPVFCAALVGGSTLLQVPLRRVIERILGTLDESAKLRLSRWLATFVAAWCSLSLLQSKPSPLFTDVVEEPSDDPSSKGGQRTIKWAGRTLDLTLFAVTRAVDVIVGELWSQRRERRMAAGKWTKTEKLIQKSADPALFALSCTAIMWAWFYTPTLLPPGYNKWIGAAAAVDVRLIEALRRFRTGEMQYGKDNGQAPLIQSMCADYKWPMAWGDPAASVPFPCEVVHMGVGPSCEHHALSRFYHSWRWSLATYLPLNLLIMARNPSFKNLKRALISASRSSAFLGAFIAFFYYGVCLARARVGPLIVGKDRAARQRIDSGICVGTGCVLCGWSILLEHPGRRKDMALFVAPRALATFLPRKYGMDKQWRENLVFAISTAVAFTCAMENQARVRGVLGNVLGSVLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCM2</accession>
    <name>G4NCM2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sodium bile acid symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_14690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718700.1">
        <property type="nucleotide sequence ID" value="XM_003718652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCM2"/>
    <dbReference type="FunCoup" id="G4NCM2">
        <property type="interactions" value="396"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NCM2"/>
    <dbReference type="GeneID" id="5048745"/>
    <dbReference type="KEGG" id="mgr:MGG_14690"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14690"/>
    <dbReference type="eggNOG" id="KOG4821">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039013_3_1_1"/>
    <dbReference type="InParanoid" id="G4NCM2"/>
    <dbReference type="OMA" id="LPIMIYH"/>
    <dbReference type="OrthoDB" id="188035at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016833">
        <property type="entry name" value="Put_Na-Bile_cotransptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640:SF5">
        <property type="entry name" value="SODIUM_BILE ACID COTRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 10 MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13593">
        <property type="entry name" value="SBF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="447" mass="49071" checksum="66082E89D58647A4" modified="2011-12-14" version="1">MVKVKAVLAKIGHIISAQLILIAFGIACLLAYFFPDVGVHGGTIKAEYSILYGAVGFIFLVSGLQLPYEKLRTHSKNWRLHIITQGISFLIIPLITLAIIHIMIAAGNLQTKVIDISVLVGMIVLSCIPTTIASNVVFTRNAGGEDAAAIVEVVIGNVFGAFVSPALVYAFMPKLPEFDEWQPASPSTLSAMYQKVAQQLGLSVLIPLAVGQVLRFFFPRHVKWALEKLYLGKISTICLALLVWTTFCGAFATGALYVTPKASLIFNIFMNIGLYLLFTVICFFSARPPLKLVTWAEGIFEKKPLCRLPTLLKRVVIPKRMSKEQTIAVCFCGAAKTTSLGIPLVTAMWNESDNLRRAFIQIPVLLYTIEQVFIAQILVYFFRRYMKRDQKDSGTDEDTVADPAGNSLEDARIPSVPVGASEKPGTQPSPVETQRENQPETTTAIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND25</accession>
    <name>G4ND25_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="14">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_00994</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="14"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717951.1">
        <property type="nucleotide sequence ID" value="XM_003717903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND25"/>
    <dbReference type="SMR" id="G4ND25"/>
    <dbReference type="STRING" id="242507.G4ND25"/>
    <dbReference type="GeneID" id="2674931"/>
    <dbReference type="KEGG" id="mgr:MGG_00994"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00994"/>
    <dbReference type="eggNOG" id="KOG2204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003818_0_2_1"/>
    <dbReference type="InParanoid" id="G4ND25"/>
    <dbReference type="OMA" id="PESFGWD"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="PHI-base" id="PHI:2488"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000047">
        <property type="entry name" value="Mannosyl-oligosaccharide alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF101">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466462" description="alpha-1,2-Mannosidase" evidence="15">
        <location>
            <begin position="26"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="519"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="334"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA48367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="531" mass="58621" checksum="0405E15974AD53FF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDX9</accession>
    <name>G4NDX9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_00176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718945.1">
        <property type="nucleotide sequence ID" value="XM_003718897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDX9"/>
    <dbReference type="GeneID" id="2674554"/>
    <dbReference type="KEGG" id="mgr:MGG_00176"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00176"/>
    <dbReference type="eggNOG" id="ENOG502SVII">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069188_1_0_1"/>
    <dbReference type="InParanoid" id="G4NDX9"/>
    <dbReference type="OMA" id="KEICACK"/>
    <dbReference type="OrthoDB" id="5207784at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="262" mass="28539" checksum="F14F4645AB4657E6" modified="2011-12-14" version="1">MSDINQSVGIPVTSYNEVVPPGYENLPPMTMTVEGQEIHAVKPGAQLLYRLSLGITTLSEITTEVQLSRIEPTKSGSERQRRIYDLKHMRRTPGGFEKVPAESPRYYIQRASRLVPGHAAVGIKKKRSLMGGKAEQVTAVPVDLSGKASKFGIPTFVKDSESIFTLKGLEWVSAAGNSVAVMYDGNKEDKAHSLVVTASLPRAQFEILVALWCCHVWEFSVTNAEKIHEGSAGLARKLRQGEEFGYRWMSGPAGGGGASGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE50</accession>
    <name>G4NE50_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Galactosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_00164</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718963.1">
        <property type="nucleotide sequence ID" value="XM_003718915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE50"/>
    <dbReference type="FunCoup" id="G4NE50">
        <property type="interactions" value="133"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NE50"/>
    <dbReference type="GeneID" id="2674489"/>
    <dbReference type="KEGG" id="mgr:MGG_00164"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00164"/>
    <dbReference type="eggNOG" id="KOG4748">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021434_0_0_1"/>
    <dbReference type="InParanoid" id="G4NE50"/>
    <dbReference type="OMA" id="GEMYHYR"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000117">
        <property type="entry name" value="Glycosyltransferase family 34 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF5">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA49379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="541" mass="61523" checksum="15DA8235B03C394A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEB3</accession>
    <name>G4NEB3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00804</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718180.1">
        <property type="nucleotide sequence ID" value="XM_003718132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEB3"/>
    <dbReference type="STRING" id="242507.G4NEB3"/>
    <dbReference type="GeneID" id="2675216"/>
    <dbReference type="KEGG" id="mgr:MGG_00804"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00804"/>
    <dbReference type="eggNOG" id="KOG1552">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029375_3_0_1"/>
    <dbReference type="InParanoid" id="G4NEB3"/>
    <dbReference type="OMA" id="WYEGRRV"/>
    <dbReference type="OrthoDB" id="446723at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="125"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="395" mass="43618" checksum="65DF69F34B6CD7B7" modified="2011-12-14" version="1">MIPWWQAILPVVVPIGTYVAFLGLLAVPPIQRFALYANRVSTLLFTNLDEPERWGFAKNQVTPFKLKVPDGEVLYGWHVLPLRTYARNENVLLKRPRGCSDDFATTDAFRILKDDPEARVVISFHGNAGHVAQGWRPAHYHTVADYSPSTHLITVDYRGFGKSTGSPTETGMLVDGMAIVDYVLDTIGIPPSRVVLFGHSLGTAVTSAVAERYASRGVDFAAIILVASFSSLPDMLSGYRIGGVIGVMRPLATICPPLNRYFLSKFVVDKWDSAGRITEMVRAVKARAGKLRLRIIHAHDDWDIPCIEADKMFTAAVGGLVGVGVEPQRLAEMKDERTVWKGKKAFATRWEEGDVDIMEEIISHGGHNEALFYAPSTLALIDAFEEGSRLQAHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEM7</accession>
    <name>G4NEM7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peroxin 24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00759</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEM7"/>
    <dbReference type="FunCoup" id="G4NEM7">
        <property type="interactions" value="61"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NEM7"/>
    <dbReference type="GeneID" id="2674143"/>
    <dbReference type="KEGG" id="mgr:MGG_00759"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00759"/>
    <dbReference type="eggNOG" id="ENOG502QQTF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024267_1_0_1"/>
    <dbReference type="InParanoid" id="G4NEM7"/>
    <dbReference type="OMA" id="QNCMDDF"/>
    <dbReference type="OrthoDB" id="74314at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052816">
        <property type="entry name" value="Peroxisomal_Membrane_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28304">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28304:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="TECPR1-like DysF" evidence="7">
        <location>
            <begin position="94"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="174"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="524" mass="57992" checksum="B1C7A61845EEC5D7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFN4</accession>
    <name>G4NFN4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14135</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719208.1">
        <property type="nucleotide sequence ID" value="XM_003719160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFN4"/>
    <dbReference type="GeneID" id="5048674"/>
    <dbReference type="KEGG" id="mgr:MGG_14135"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14135"/>
    <dbReference type="eggNOG" id="ENOG502RVYR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_548689_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFN4"/>
    <dbReference type="OrthoDB" id="3473305at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35910:SF1">
        <property type="entry name" value="2EXR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="497" mass="55756" checksum="F2A52884628721B2" modified="2011-12-14" version="1">MTKEKATGRTWNTIPPELRLEIYKKLWVPRTVTIYRSAHHDVNTSFEHQVLSLARSQDRDRFEQDVAIDALSVAAHCPAIQVPREDPVPDANNDPLTAGNGFLCGPHGHWDANWLRLVRDSMPPDADASGSAPNGPSRQLLPPPLYTTTTSARVDRSTLVPITLWIDRESRAETLKHYRPAFALRGGATRVYFNFALDTLRIPVHGKLWRLVQRRDLQDLVRLRMVGTADDPSGSRSRSLNPTAATTHNPAEPPAAMGSLLRALCPRLRHVTVEPAWGCARNNLAWRRHEMDDNLVIFNWREIGELQVGCSSCTWNHGHRPCGVLLRRLRELKWMVDMPLIMPGSNGPSEPGLVLTFHSSRPIDDFVNGGDDGYGVPGYVRSDETNPGLDEARVKSTLFLDGQHPRASVEEDFHRLCTINAMQHNIRLACDLTTHPAGQMNNSIDCKFEFPPSVSDQKTILWVRSLIACNPDASMSMLQYVLKLQMAGQSQRVEYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFT6</accession>
    <name>G4NFT6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-lactate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_08725</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719259.1">
        <property type="nucleotide sequence ID" value="XM_003719211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFT6"/>
    <dbReference type="SMR" id="G4NFT6"/>
    <dbReference type="STRING" id="242507.G4NFT6"/>
    <dbReference type="GeneID" id="2678994"/>
    <dbReference type="KEGG" id="mgr:MGG_08725"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08725"/>
    <dbReference type="eggNOG" id="KOG0068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_1_1"/>
    <dbReference type="InParanoid" id="G4NFT6"/>
    <dbReference type="OMA" id="VIVTAHQ"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12183">
        <property type="entry name" value="LDH_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058205">
        <property type="entry name" value="D-LDH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43026:SF1">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="16"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="115"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA46892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="349" mass="38032" checksum="7674492BA2667AFB" modified="2011-12-14" version="1">MKLAIFSAKGYDKKYFSQVQAAHEKLSNIDLSFIDFPLSPDTVQLAKGAEAVCAFVNDNLSRPVLEGLSDLGVTTILLRCAGFNNVDLDCASQLGLSVANVPSYSPEAVGEFAVALLQTVNRKTHRAYNRVREGNFNLDGLLGRTLHGKTVGVVGTGRIGIAFARIMVGFGCKLLAYDVYQNEEVGKLGGSYESLDEVLSKSDFVSLHCPLMEATRHLINSTTLAKMKPDAILINTSRGGLIDTKAVIKALKARELGGLALDVYEGEGALFYNDHSADIIQDDELMRLMTFPNVVVCGHQAFFTEEALTEIAECSFRNLDDLANGRECKNSLVAAKKPLLRRESIPHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFT7</accession>
    <name>G4NFT7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD dependent epimerase/dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719261.1">
        <property type="nucleotide sequence ID" value="XM_003719213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFT7"/>
    <dbReference type="SMR" id="G4NFT7"/>
    <dbReference type="STRING" id="242507.G4NFT7"/>
    <dbReference type="GeneID" id="2678991"/>
    <dbReference type="KEGG" id="mgr:MGG_08722"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08722"/>
    <dbReference type="eggNOG" id="ENOG502RY15">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061199_2_1_1"/>
    <dbReference type="InParanoid" id="G4NFT7"/>
    <dbReference type="OMA" id="ANDGETM"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF3">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="29526" checksum="0068B3F91BAFD903" modified="2011-12-14" version="1">MGGVASIPSTDPACTLQVIGAGFSRTGTVSMALALEKLLGGPVCHGGTQMHMLGDEYARRWVEVYEARHDRPELLRRLREVTRGFVGITDMPGVHFVEELLELYPEARVVGVRRDADRWWKSANEMHDKMTPWYMDVLLWPVPTSRWFARWHELAMERTKELGLLPFGPEYLDRYNDWVSRVVPEEKIVWMEMKDEWGPLCKMLDKPKPDLPFPRANDAEAAEGLIREKVKKATFIWSGIIGAIAISAAVAHRIYRHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG82</accession>
    <name>G4NG82_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_17613</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719406.1">
        <property type="nucleotide sequence ID" value="XM_003719358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG82"/>
    <dbReference type="GeneID" id="12985897"/>
    <dbReference type="KEGG" id="mgr:MGG_17613"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17613"/>
    <dbReference type="eggNOG" id="ENOG502SZCW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019059_0_0_1"/>
    <dbReference type="InParanoid" id="G4NG82"/>
    <dbReference type="OMA" id="HQYATHF"/>
    <dbReference type="OrthoDB" id="4847360at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032567">
        <property type="entry name" value="RTL1-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503">
        <property type="entry name" value="LDOC1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503:SF22">
        <property type="entry name" value="TRANSPOSON TY3-I GAG POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="355" mass="40711" checksum="1C579AEDB1243E52" modified="2011-12-14" version="1">MSSQSSKNNTPSTPATSSKAAQKAPARPKDDSDSEDEEDQLRRQVARTNQELHEQTLRATQLQEELQALRASANVTSTPLDGRERLKLNPPATFDGTPGQLKGYLVQVRTYQAFHLETFRSETEKVVHAATFLRGRALSWFEPLLQEWLDVPPEERRQEVTDIFSTFAGYERTLRSLFQEPDEKRQTERDLANLRQTKSASAYAAEFRRLATRLDMTEETKILQFYQGLKSEIKDEVSKLDRPEDFLDGPMDLSATQHKKPRKDPKNGKCFKCDKTGHIARNCPRNQEDIPDFRGKTEKPRGLNATNYQQLRPNQHSTMSWTTCYDDNCMTHNSSKIDAGWYPQKPRGTRTLAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGM5</accession>
    <name>G4NGM5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kelch repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_14917</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719752.1">
        <property type="nucleotide sequence ID" value="XM_003719704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGM5"/>
    <dbReference type="SMR" id="G4NGM5"/>
    <dbReference type="STRING" id="242507.G4NGM5"/>
    <dbReference type="GeneID" id="12986202"/>
    <dbReference type="KEGG" id="mgr:MGG_14917"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14917"/>
    <dbReference type="eggNOG" id="KOG4441">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004253_10_0_1"/>
    <dbReference type="InParanoid" id="G4NGM5"/>
    <dbReference type="OMA" id="ERETSWE"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46344:SF27">
        <property type="entry name" value="KELCH REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46344">
        <property type="entry name" value="OS02G0202900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466219" description="Kelch repeat-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="36390" checksum="8B714142FBCF1612" modified="2011-12-14" version="1">MRVTISTFWIICSSLLHLSNGAAVRRAQGTWDELTSTPILPRQENTAVGINSTSLAVLGGIVTNGTQVRSSALASIYHVPTNQWQQIADLPIPLNHPNAAVINGKIYLLGGLADIDGIWKGVPNAWVWDPETDTWNDLEPFPTDTERGSAAVAVVGDTVYLAGGQRSLALVPGGLHDTVDTVSAFDTLSGKWKLLPNLALPEPRDHAGAAVVGTKLFVTGGRHLREGLIVSGKVYSVDFAAEEPRWTLEDEQMPTARGGHMAAAIGDQVYTFGGEGSGKSDSGVFDEVEVLDTTTGIWSRREPMRLPRHGTYAVAIGGAIYIPGGGLQQGAGAATDGFDVFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH18</accession>
    <name>G4NH18_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Retinol dehydrogenase 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_12116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719895.1">
        <property type="nucleotide sequence ID" value="XM_003719847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH18"/>
    <dbReference type="SMR" id="G4NH18"/>
    <dbReference type="STRING" id="242507.G4NH18"/>
    <dbReference type="GeneID" id="5049878"/>
    <dbReference type="KEGG" id="mgr:MGG_12116"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12116"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="InParanoid" id="G4NH18"/>
    <dbReference type="OMA" id="ANMPERY"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="48093" checksum="A78BDC157C71E249" modified="2011-12-14" version="1">MSCHWIFYRNYSILHLGAGLPFSYLPYIDFGGFFFLSLFCSSCFSCCLVNPKDGRLRPATIMTSEQQPPSPPTASQKRHAFSWFTDANYLSIGPSFVTNFIRNQLKTLPEPKSDFTGKTVIVTGGNSGLGREAARYFARLGAAKVILACRDTAKGEVARADIEVSTRSSRPPSAAGVRLAVEVWQVDMSSGSSVHDFCARVERELPRLDSLVLNAGVAIGAFVECEGGWESSVAINVIGTFLMAVLCLPIMRRTAAQHNVAPTIAVVASEAHVFASFAERKRQGLIFDAFKSAADMNEDRYNVTKLLDVLLARELAARLGPDSPVVVNALNPGLCQSELFRHCPFPLSALLRLGLMILGRKTEVGSRTLVAAAAAGRETHGKYMDSCELANESAFVRSDEGRASGVRVFDELMGIMEGLAPGARGNLNASTTTSMATAPASTAQASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH70</accession>
    <name>G4NH70_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HET-C protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Kulkarni R."/>
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                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
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                <person name="Abouelleil A."/>
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                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Priest M."/>
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                <person name="Nusbaum C."/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
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                <person name="Bohnert H."/>
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                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720335.1">
        <property type="nucleotide sequence ID" value="XM_003720287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIA8"/>
    <dbReference type="GeneID" id="12987296"/>
    <dbReference type="KEGG" id="mgr:MGG_17824"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17824"/>
    <dbReference type="HOGENOM" id="CLU_1396597_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIA8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466374" description="Cell wall protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="20763" checksum="533C9894CA4B9154" modified="2011-12-14" version="1">MRFQTTVALIAVVGMTAATAVQPRQDISADDAELTRKCKAAAETLDKEVKTPETLEKIFKADVCELIKLEKELDPKKLEEEAVKYNKDLETWAAQSDENMETLTEATVCLVTALAVLGAAGEVLKQQGVNVEKALEDALKEEAKKCKDSPSAIGTPYPTNPGTATTSPAKDASARSVVPLGLGAVAFVVLAVLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIF6</accession>
    <name>G4NIF6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_15421</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720383.1">
        <property type="nucleotide sequence ID" value="XM_003720335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIF6"/>
    <dbReference type="SMR" id="G4NIF6"/>
    <dbReference type="STRING" id="242507.G4NIF6"/>
    <dbReference type="GeneID" id="12987328"/>
    <dbReference type="KEGG" id="mgr:MGG_15421"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15421"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_19_5_1"/>
    <dbReference type="InParanoid" id="G4NIF6"/>
    <dbReference type="OMA" id="WPQYAVH"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005720">
        <property type="entry name" value="PRK07538.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF268">
        <property type="entry name" value="5-METHYLPHENAZINE-1-CARBOXYLATE 1-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="9"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="306"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA48016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="443" mass="48686" checksum="4281284A593F269A" modified="2011-12-14" version="1">MPYMSSQPKVLIAGGGIGGLSTALALHASGLTDIHIFEAAGKLTSLGVGINVQPSAVLILRNLGLLPELERTGVVTQELNFYNRHGDEILSEPRGTKAGYACPQLSIHRGNFQMVLLDAVRKRIGEDRIHLGHALVNFQQDDKSITGFFKHAENTKDPVPSMTGDVLIAADGINSATRKILYPNEGPPRFSGRILWRGCIEREPYLTGGSMVWAGFADQKFIAYPISGESARNGKSLVNWIAELRVRDDSDPDKTPPKVDWTKTVPKERFAGPFKGWTCGGLRMIEDLIAPTERVFEFPMCDRDPLERWSFGRLTLTGDAAHCMYPIGSNGATQAIIDAETIAQCLTGTETEKIPEALKKYEEIRLPPTAKIVYANRANGPDHVLQLAEERAPEGFKNVYDVIPKEELESIGAKYKAIAGFELEAVNKKAKETEELAARFAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJZ4</accession>
    <name>G4NJZ4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720505.1">
        <property type="nucleotide sequence ID" value="XM_003720457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJZ4"/>
    <dbReference type="GeneID" id="5048711"/>
    <dbReference type="KEGG" id="mgr:MGG_14216"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14216"/>
    <dbReference type="eggNOG" id="ENOG502STWX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1661117_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJZ4"/>
    <dbReference type="OrthoDB" id="2832510at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA45762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="17915" checksum="E545DAEF82F5F7F8" modified="2011-12-14" version="1">MRKFLESIFWPNRAASPSVARDYYRQADMLQAPHLAGSKSRIDFRSLAVAPEFQRRGYGETMVQWLGLQAWEEDVPVFGDASTNGLPIYLRNQCKEIGKIHLKQQVVGLGSGKDCLICSPMDVICLRWKSPEGVPIWDAASHFKFVAEKPTDISGMLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKJ9</accession>
    <name>G4NKJ9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720617.1">
        <property type="nucleotide sequence ID" value="XM_003720569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKJ9"/>
    <dbReference type="GeneID" id="12984738"/>
    <dbReference type="KEGG" id="mgr:MGG_15039"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15039"/>
    <dbReference type="HOGENOM" id="CLU_2158924_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKJ9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA45874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="111" mass="12518" checksum="BBCEB49EEE77F0BD" modified="2011-12-14" version="1">MQRNAAEREENAARFELVGTVQGAPTTQRKTPMLDNAALGPDIVVECDVCAFRLLEKEARFWKTDPQFYVAKEQGVQQKRPLDEEPAQVLNENACEPDLARECQASEIPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLF5</accession>
    <name>G4NLF5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721499.1">
        <property type="nucleotide sequence ID" value="XM_003721451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLF5"/>
    <dbReference type="GeneID" id="5051421"/>
    <dbReference type="KEGG" id="mgr:MGG_14063"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14063"/>
    <dbReference type="HOGENOM" id="CLU_1949250_0_0_1"/>
    <dbReference type="InParanoid" id="G4NLF5"/>
    <dbReference type="OrthoDB" id="5102063at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="129" mass="13700" checksum="A61FFFC72F060155" modified="2011-12-14" version="1">MIDGGKTVSHSVVPKQAPVPTHHHLQRIDVVIDTGHPSSQPLSACQDQTDGLFLCASCCGAHSRSEQAEGRFLNKCEARASLVGSPPGEAGLGFGHGETNSYGKLETMPRYAARDGNISCDLTDQIEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHC3</accession>
    <name>G5EHC3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGCH7_ch7g817</name>
        <name evidence="7" type="ORF">MGG_03030</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15</strain>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">70-15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720657.1">
        <property type="nucleotide sequence ID" value="XM_003720609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHC3"/>
    <dbReference type="SMR" id="G5EHC3"/>
    <dbReference type="GeneID" id="2682583"/>
    <dbReference type="KEGG" id="mgr:MGG_03030"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03030"/>
    <dbReference type="eggNOG" id="ENOG502S8YJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053382_0_0_1"/>
    <dbReference type="OMA" id="DCEPCNR"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38846:SF1">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13894">
        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="32"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="61"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EAQ71410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA45914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="255" mass="28763" checksum="51CA086CAB44E995" modified="2011-12-14" version="1">MDAVCALCDRLFVSEESLEQHLRDSPAHASVYECEKCDRSFNSDEALQQHVRDSPAHAATFDCETCDRSFKTDEALQQHLESAAVHQTQLQLASKTPLDEFFLSFEDFAYNPSDPPAKSFARLEKHRGWAADGSASRKAWRKYQTALASELDMWYGPTDDLTAWHTLCRAIGIKPLPESCTQCKKAVSKKHVNIVDLIDWSRNRGTSETPVQTFPSVAQLQAYTIKTRKIFSKEKAKAGAQGKKAVLKHLLRKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHR4</accession>
    <name>G5EHR4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-dehydropantoate 2-reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGCH7_ch7g562</name>
        <name evidence="5" type="ORF">MGG_02809</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15</strain>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EAQ71155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720932.1">
        <property type="nucleotide sequence ID" value="XM_003720884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHR4"/>
    <dbReference type="SMR" id="G5EHR4"/>
    <dbReference type="GeneID" id="2682362"/>
    <dbReference type="KEGG" id="mgr:MGG_02809"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02809"/>
    <dbReference type="eggNOG" id="ENOG502QT3Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021479_0_0_1"/>
    <dbReference type="OMA" id="IWVGATN"/>
    <dbReference type="OrthoDB" id="5302359at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000424">
        <property type="entry name" value="Meiotically up-regulated gene 72 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF25">
        <property type="entry name" value="PROTEIN PAM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="3">
        <location>
            <begin position="200"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="727"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="750"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="760"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EAQ71155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA46189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="786" mass="84441" checksum="A252CC6DA774F13B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHR7</accession>
    <name>G5EHR7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g94</name>
        <name evidence="3" type="ORF">MGG_18065</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721409.1">
        <property type="nucleotide sequence ID" value="XM_003721361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHR7"/>
    <dbReference type="GeneID" id="12986016"/>
    <dbReference type="KEGG" id="mgr:MGG_18065"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18065"/>
    <dbReference type="HOGENOM" id="CLU_2027189_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="122" mass="13922" checksum="A5B80B9E45F9FF43" modified="2011-12-14" version="1">MDRNFKYKFGRAVPERITSKERTDMPKSGCTLRNKLRFDKWQLFVGAFVMAVDIPPHCDRIYLWVVQTDRTGGTTSVFRIFMHCFQAQIRGVIRPTPTWRPSPILPGAGSTVPSDSPSNFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHS2</accession>
    <name>G5EHS2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">COP9 signalosome complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGCH7_ch7g1103</name>
        <name evidence="12" type="ORF">MGG_10325</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15</strain>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720496.1">
        <property type="nucleotide sequence ID" value="XM_003720448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHS2"/>
    <dbReference type="SMR" id="G5EHS2"/>
    <dbReference type="STRING" id="242507.G5EHS2"/>
    <dbReference type="GeneID" id="2681900"/>
    <dbReference type="KEGG" id="mgr:MGG_10325"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10325"/>
    <dbReference type="eggNOG" id="KOG1464">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028981_0_1_1"/>
    <dbReference type="OMA" id="SEENWKD"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000006">
        <property type="entry name" value="COP9 signalosome complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="10">
        <location>
            <begin position="253"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EAQ71696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA45753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="522" mass="59005" checksum="A5C5E582C540AA05" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-08-30" modified="2025-06-18" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>Q51NJ3</accession>
    <accession>A4RDY5</accession>
    <accession>G4NE29</accession>
    <name>PALA_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>pH-response regulator protein palA/RIM20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">RIM20</name>
        <name type="ORF">MGG_00833</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. May act as a scaffold protein that recruits the calpain-like protease RIM13 via VPS32 to its substrate RIM101.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with RIM101 by binding to its two YPX[LI] motifs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the palA/RIM20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718148.1">
        <property type="nucleotide sequence ID" value="XM_003718100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q51NJ3"/>
    <dbReference type="SMR" id="Q51NJ3"/>
    <dbReference type="FunCoup" id="Q51NJ3">
        <property type="interactions" value="1182"/>
    </dbReference>
    <dbReference type="STRING" id="242507.Q51NJ3"/>
    <dbReference type="EnsemblFungi" id="MGG_00833T0">
        <property type="protein sequence ID" value="MGG_00833T0"/>
        <property type="gene ID" value="MGG_00833"/>
    </dbReference>
    <dbReference type="GeneID" id="2674260"/>
    <dbReference type="KEGG" id="mgr:MGG_00833"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00833"/>
    <dbReference type="eggNOG" id="KOG2220">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007181_0_0_1"/>
    <dbReference type="InParanoid" id="Q51NJ3"/>
    <dbReference type="OMA" id="VSHAEEM"/>
    <dbReference type="OrthoDB" id="64867at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09241">
        <property type="entry name" value="BRO1_ScRim20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.560">
        <property type="entry name" value="alix/aip1 in complex with the ypdl late domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.50">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025304">
        <property type="entry name" value="ALIX_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF39">
        <property type="entry name" value="PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13949">
        <property type="entry name" value="ALIX_LYPXL_bnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0175">Coiled coil</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000218881" description="pH-response regulator protein palA/RIM20">
        <location>
            <begin position="1"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="BRO1" evidence="3">
        <location>
            <begin position="7"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="475"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="738"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="260"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="745"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="802"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="820"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="849" mass="95377" checksum="45179BB848DB18CC" modified="2005-06-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>A4R2R5</accession>
    <name>A4R2R5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11904</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709245.1">
        <property type="nucleotide sequence ID" value="XM_003709197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R2R5"/>
    <dbReference type="STRING" id="242507.A4R2R5"/>
    <dbReference type="GeneID" id="5049696"/>
    <dbReference type="KEGG" id="mgr:MGG_11904"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11904"/>
    <dbReference type="eggNOG" id="ENOG502S4R7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030267_0_0_1"/>
    <dbReference type="InParanoid" id="A4R2R5"/>
    <dbReference type="OMA" id="AHEDWDY"/>
    <dbReference type="OrthoDB" id="2157498at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029164">
        <property type="entry name" value="PIG-Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39400:SF1">
        <property type="entry name" value="PIG-P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39400">
        <property type="entry name" value="YALI0E29227P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15159">
        <property type="entry name" value="PIG-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="396" mass="42384" checksum="7BF0C285F69643EA" modified="2007-05-15" version="1">MDASLASAAPPPSAVGGHRGLLSKIPFMRSHGVSQASHQHQHPPPPEGQVHGTVTGVDAGHIPGPSPIPTALQQQKTRRRRGSLRKVALLGRGAQRERRDMSDSSAAAVVAASGISLVVPPKDVDSSTGLAAASSPSFPLSLTAATQVNIANDAESPPGSNTPGKTPRPPSQNNIARPVVGVKSRSTSPSAAAWSALPPIDIPPNTRVVEESSTATASYSTTDDEDALRLPRRASNKSSLLRPGIPSTSGSESYFSGGLPAPRANLQRRRSGNRVRSPLALGSLNSSPMNSGGLIQQAAEWDYDETERWGWIILFITWFVFVMGMGSVTGIWTWVWDVGPDTVYPAWLEAWDDPTLPIDGYYPSLLLLTFVMVWVWVVVSWMGMKYFRHAKINGDH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-03-08" modified="2025-06-18" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4RHN5</accession>
    <accession>G4MT28</accession>
    <name>CHO2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylethanolamine N-methyltransferase</fullName>
            <shortName evidence="1">PE methyltransferase</shortName>
            <shortName evidence="1">PEAMT</shortName>
            <shortName evidence="1">PEMT</shortName>
            <ecNumber evidence="1">2.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">CHO2</name>
        <name type="ORF">MGG_07110</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11164"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64573"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="2.1.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.</text>
    </comment>
    <comment type="sequence caution" evidence="3">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="EHA55493" version="1"/>
        </conflict>
        <text>Extended N-terminus.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.17" evidence="1"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55493.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715300.1">
        <property type="nucleotide sequence ID" value="XM_003715252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RHN5"/>
    <dbReference type="SMR" id="A4RHN5"/>
    <dbReference type="FunCoup" id="A4RHN5">
        <property type="interactions" value="63"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RHN5"/>
    <dbReference type="GeneID" id="2683232"/>
    <dbReference type="KEGG" id="mgr:MGG_07110"/>
    <dbReference type="eggNOG" id="ENOG502QRGH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A4RHN5"/>
    <dbReference type="OrthoDB" id="4583at2759"/>
    <dbReference type="UniPathway" id="UPA00753"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004608">
        <property type="term" value="F:phosphatidylethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03217">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016219">
        <property type="entry name" value="Phosphatid-EA_MeTrfase_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32138">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32138:SF0">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000383">
        <property type="entry name" value="PEAMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51598">
        <property type="entry name" value="SAM_CHO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword id="KW-1208">Phospholipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000405895" description="Phosphatidylethanolamine N-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="121"/>
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        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="1">
        <location>
            <begin position="142"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="228"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="1">
        <location>
            <begin position="256"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="306"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="1">
        <location>
            <begin position="333"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="407"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="1">
        <location>
            <begin position="435"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="1">
        <location>
            <begin position="517"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="591"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="963" mass="108358" checksum="D7E65D9EB2E4E04C" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKH4</accession>
    <name>G4MKH4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710175.1">
        <property type="nucleotide sequence ID" value="XM_003710127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKH4"/>
    <dbReference type="STRING" id="242507.G4MKH4"/>
    <dbReference type="GeneID" id="2676098"/>
    <dbReference type="KEGG" id="mgr:MGG_05339"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05339"/>
    <dbReference type="eggNOG" id="ENOG502SNNV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055334_2_0_1"/>
    <dbReference type="InParanoid" id="G4MKH4"/>
    <dbReference type="OMA" id="YAWIEQA"/>
    <dbReference type="OrthoDB" id="3858188at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="296" mass="33024" checksum="864DFBD8604AE8C7" modified="2011-12-14" version="1">MAHYLHPVAVDTPIKSPPPPLSPLPALNSGIQVPNPKTSSVISLTVSQKEAPRAESELSRYLRIVRRMKWKLPFLAQGYQQATDATSAEFADADMMFKLDFFEYYMLLERALVHLQAVFNIVITGKHNESSSSSSNGTGPYKHRYHANVLEALDSTDNPLHGALGKGDVRRALGRAKDLRNRWKNADDANRDPATNLPLESYDLENILTTIYGGLDQACIVATNYVNELKAIAAAAARASAAAYPKFSWADEMETPTPGREDRPPPFEEWPAQEKSKTDEEAEWQFMFDAMDWQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKH8</accession>
    <name>G4MKH8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T2</fullName>
            <ecNumber evidence="2">4.6.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RNase T2 family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.19" evidence="2"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710179.1">
        <property type="nucleotide sequence ID" value="XM_003710131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKH8"/>
    <dbReference type="SMR" id="G4MKH8"/>
    <dbReference type="FunCoup" id="G4MKH8">
        <property type="interactions" value="141"/>
    </dbReference>
    <dbReference type="GeneID" id="2676147"/>
    <dbReference type="KEGG" id="mgr:MGG_05342"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05342"/>
    <dbReference type="eggNOG" id="KOG1642">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037966_1_2_1"/>
    <dbReference type="InParanoid" id="G4MKH8"/>
    <dbReference type="OMA" id="EDTCCFI"/>
    <dbReference type="OrthoDB" id="435754at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01061">
        <property type="entry name" value="RNase_T2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033697">
        <property type="entry name" value="Ribonuclease_T2_eukaryotic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240:SF22">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR633697-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA57567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="318" mass="34759" checksum="533DCFDBC467FA48" modified="2011-12-14" version="1">MAPQQSIRALLAYAGNIFSQVPLGGIANPFDSGSAVVGNTGVQQQQCHYSPLTGAPACPIDGPMSCHNSTPVEGNSCCFVHPGGQLMLTQFWDQDIHEGGSDEDWTIHGLWPDLCNGGYEQFCNIAPQYRNITEILHAHGQADLVSYMNRYWVADRGTNDHLWEHEWNKHGTCINTLAPACYSAPSSSSCSSTNAAVASPGEMAVVDYFTRAVALFKTLDTYTALERAGIVPHARKRYPLVDVQKALAEYLGGGKVALRCRGGNRHRKGDVLNEAWFVYYVKGSLQTGEFVPAPPTGRDATNCAPWIKYPPKRRRGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKK6</accession>
    <name>G4MKK6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711001.1">
        <property type="nucleotide sequence ID" value="XM_003710953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKK6"/>
    <dbReference type="GeneID" id="12986878"/>
    <dbReference type="KEGG" id="mgr:MGG_16525"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16525"/>
    <dbReference type="HOGENOM" id="CLU_2590201_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKK6"/>
    <dbReference type="OrthoDB" id="10446685at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA58389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="80" mass="8831" checksum="3D28C0BA96B0FE83" modified="2011-12-14" version="1">MSRDVEAGCIGLNTQEFKRGTAAKPSAFLLPPEQQVRIILITTSAQVCSFPGRQIGQEDKLRVYAEFFIVLCSFPGRPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKQ7</accession>
    <name>G4MKQ7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06653</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709359.1">
        <property type="nucleotide sequence ID" value="XM_003709311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKQ7"/>
    <dbReference type="STRING" id="242507.G4MKQ7"/>
    <dbReference type="GeneID" id="2684826"/>
    <dbReference type="KEGG" id="mgr:MGG_06653"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06653"/>
    <dbReference type="eggNOG" id="ENOG502S40X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053381_1_1_1"/>
    <dbReference type="InParanoid" id="G4MKQ7"/>
    <dbReference type="OMA" id="CQNGMVM"/>
    <dbReference type="OrthoDB" id="2331100at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF17">
        <property type="entry name" value="CUPREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465322" description="Extracellular serine-rich protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="23166" checksum="99DFCF6DBB857B3C" modified="2011-12-14" version="1">MQFATVALAALAMFTGVDAQQVHAVRVGQNGTIFSPNKITARTGDMVQFMFMGGNHTVTQSPFDDPCQPISKTMKNVTGVHTGFVPFAASAAMGKIPVYTIRVNNTNPIWLYCATGPHCKNGMVMVINEPTNPQRSLAEYKKAASQITGAAGVPGGPSGGQSGTTPSTGGTGGGSTGGNGSTGGTGSGTGTGSGGSTPGGSAPGASGSPAPVPAAGSMVAPSLGLIALAAFSYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMB9</accession>
    <name>G4MMB9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CCT-beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_01979</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708717.1">
        <property type="nucleotide sequence ID" value="XM_003708669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMB9"/>
    <dbReference type="SMR" id="G4MMB9"/>
    <dbReference type="FunCoup" id="G4MMB9">
        <property type="interactions" value="1387"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MMB9"/>
    <dbReference type="GeneID" id="2681098"/>
    <dbReference type="KEGG" id="mgr:MGG_01979"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01979"/>
    <dbReference type="eggNOG" id="KOG0363">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008891_6_2_1"/>
    <dbReference type="InParanoid" id="G4MMB9"/>
    <dbReference type="OMA" id="CAEMVMS"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03336">
        <property type="entry name" value="TCP1_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000002">
        <property type="entry name" value="T-complex protein 1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012716">
        <property type="entry name" value="Chap_CCT_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02341">
        <property type="entry name" value="chap_CCT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA56105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="530" mass="57055" checksum="7E7C5768876260C0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMP5</accession>
    <name>G4MMP5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710429.1">
        <property type="nucleotide sequence ID" value="XM_003710381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMP5"/>
    <dbReference type="GeneID" id="12986333"/>
    <dbReference type="KEGG" id="mgr:MGG_15152"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15152"/>
    <dbReference type="HOGENOM" id="CLU_1057969_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMP5"/>
    <dbReference type="OrthoDB" id="5241827at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="263" mass="28757" checksum="0F17553E01C44AD5" modified="2011-12-14" version="1">MSFNTQSSTTTNSTGQQPGLQSSYWRAEKPSYSPYQAGDAFVNPLMLSSPQHKTSEPSPDFASLLASAAAAAQTQLATTDNIDIDIDGHIYSDGHTSSDDNMSDVGGDESTGATAMPDTIDELATYSDDVVGAHAGLLPYLAGRYTNPGLYLQLARVAFLRQGRERPQVEWPRVEIEAETPVVVERRRGQSLGAILMRHKLSLLEEQLARLGQQQLPQEQEQELGGGQDTEAGFWDGQEYQEDQVSGFRVDEDGDVEMEDAWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNK7</accession>
    <name>G4MNK7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Protein phosphatase PP2A regulatory subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_05637</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase. The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710525.1">
        <property type="nucleotide sequence ID" value="XM_003710477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNK7"/>
    <dbReference type="SMR" id="G4MNK7"/>
    <dbReference type="FunCoup" id="G4MNK7">
        <property type="interactions" value="754"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MNK7"/>
    <dbReference type="GeneID" id="2676039"/>
    <dbReference type="KEGG" id="mgr:MGG_05637"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05637"/>
    <dbReference type="eggNOG" id="KOG1354">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021713_3_3_1"/>
    <dbReference type="InParanoid" id="G4MNK7"/>
    <dbReference type="OMA" id="NQIKWCR"/>
    <dbReference type="OrthoDB" id="6274823at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005934">
        <property type="term" value="C:cellular bud tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000705">
        <property type="term" value="P:achiasmate meiosis I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071475">
        <property type="term" value="P:cellular hyperosmotic salinity response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045143">
        <property type="term" value="P:homologous chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016237">
        <property type="term" value="P:microautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044818">
        <property type="term" value="P:mitotic G2/M transition checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001100">
        <property type="term" value="P:negative regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010515">
        <property type="term" value="P:negative regulation of induction of conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031030">
        <property type="term" value="P:negative regulation of septation initiation signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000786">
        <property type="term" value="P:positive regulation of autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010971">
        <property type="term" value="P:positive regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905477">
        <property type="term" value="P:positive regulation of protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900182">
        <property type="term" value="P:positive regulation of protein localization to nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061586">
        <property type="term" value="P:positive regulation of transcription by transcription factor localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090266">
        <property type="term" value="P:regulation of mitotic cell cycle spindle assembly checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000174">
        <property type="entry name" value="Protein phosphatase PP2A regulatory subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000189">
        <property type="entry name" value="Protein phosphatase PP2A regulatory subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000009">
        <property type="entry name" value="PP2A_PR55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018067">
        <property type="entry name" value="PP2A_PR55_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11871">
        <property type="entry name" value="PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037309">
        <property type="entry name" value="PP2A_PR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00600">
        <property type="entry name" value="PP2APR55"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01024">
        <property type="entry name" value="PR55_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01025">
        <property type="entry name" value="PR55_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="405"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00067298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU331113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA57913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="481" mass="54025" checksum="ADFE6576290E6A2F" modified="2011-12-14" version="1">MVEADTNSPTWKFTQCFGDKGDVEDITEADIISTVEFDHTGNYLATGDKGGRVVLFERNETKKTCEYKFHTEFQSHEPEFDYLKSLEIEEKINKIKWCRRQNASHYLLSTNDKTIKLWKVFEKSLKVVAENNLSHDLTPANIAGGGGAPRPPPASTFRNAADLKLPRLTHHDTVVAAVPRRTYANAHAYHINSISVNSDGETFISSDDLRINLWNLNIQEQSFNIVDIKPANMEELTEVITAAEFHPASCNVFMYASSKGTIKLADMRESALCDQHAKMFEQEEDPSSRSFFSEIISSISDVRFSYDGRYVLSRDYLTVKIWDVNMEKQPVKTIPIHEHLRPRLCDTYENDSIFDKFEVVFSGDAKNVMTGSYNNNFMIYPSDPEKETEVVLQADKSAFKAKKVGVPTPINSSTSPTANGGKKGGSRAGSPAAGGQGQRMRKETDADQIDFNKKILHMSWHPFEDSIAIAATNNLFVFSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPC5</accession>
    <name>G4MPC5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450 52A11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_09179</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709790.1">
        <property type="nucleotide sequence ID" value="XM_003709742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPC5"/>
    <dbReference type="SMR" id="G4MPC5"/>
    <dbReference type="STRING" id="242507.G4MPC5"/>
    <dbReference type="GeneID" id="2680246"/>
    <dbReference type="KEGG" id="mgr:MGG_09179"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09179"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020492_2_0_1"/>
    <dbReference type="InParanoid" id="G4MPC5"/>
    <dbReference type="OMA" id="ILLQWTF"/>
    <dbReference type="OrthoDB" id="10029320at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11051">
        <property type="entry name" value="CYP59-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF222">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE STCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA57178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="561" mass="63666" checksum="13A6C1A0B5AE09BB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPJ3</accession>
    <name>G4MPJ3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05737</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710648.1">
        <property type="nucleotide sequence ID" value="XM_003710600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPJ3"/>
    <dbReference type="SMR" id="G4MPJ3"/>
    <dbReference type="FunCoup" id="G4MPJ3">
        <property type="interactions" value="1118"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MPJ3"/>
    <dbReference type="GeneID" id="2675844"/>
    <dbReference type="KEGG" id="mgr:MGG_05737"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05737"/>
    <dbReference type="eggNOG" id="KOG1769">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148322_0_1_1"/>
    <dbReference type="InParanoid" id="G4MPJ3"/>
    <dbReference type="OMA" id="MKIYCAR"/>
    <dbReference type="OrthoDB" id="442921at2759"/>
    <dbReference type="PHI-base" id="PHI:8038"/>
    <dbReference type="PHI-base" id="PHI:8045"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16116">
        <property type="entry name" value="Ubl_Smt3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000155">
        <property type="entry name" value="Ubiquitin-like protein SMT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="32"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="109" mass="11643" checksum="65097AB285F9ACB1" modified="2011-12-14" version="1">MSDRENGGSPHGDYPGAGGGAPAGGGDPAAPEHLNIKVTDNNNEVFFKIKRSTKLEKLMNAFCDRQGKSLSQVRFLFDGQRVQPTDTPDTLEMADGDTLEVHQEQVGGA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2014-07-09" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPQ7</accession>
    <name>XYN6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Endo-1,4-beta-xylanase 6</fullName>
            <shortName>Xylanase 6</shortName>
            <ecNumber>3.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>1,4-beta-D-xylan xylanohydrolase 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">XYL6</name>
        <name type="ORF">MGG_02245</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text>Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyl hydrolase 10 (cellulase F) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709018.1">
        <property type="nucleotide sequence ID" value="XM_003708970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPQ7"/>
    <dbReference type="SMR" id="G4MPQ7"/>
    <dbReference type="STRING" id="242507.G4MPQ7"/>
    <dbReference type="CAZy" id="CBM1">
        <property type="family name" value="Carbohydrate-Binding Module Family 1"/>
    </dbReference>
    <dbReference type="CAZy" id="GH10">
        <property type="family name" value="Glycoside Hydrolase Family 10"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_02245T0">
        <property type="protein sequence ID" value="MGG_02245T0"/>
        <property type="gene ID" value="MGG_02245"/>
    </dbReference>
    <dbReference type="GeneID" id="2681342"/>
    <dbReference type="KEGG" id="mgr:MGG_02245"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02245"/>
    <dbReference type="eggNOG" id="ENOG502QSCW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020161_2_1_1"/>
    <dbReference type="InParanoid" id="G4MPQ7"/>
    <dbReference type="OMA" id="PENQMKW"/>
    <dbReference type="OrthoDB" id="3055998at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="PHI-base" id="PHI:2207"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044846">
        <property type="entry name" value="GH10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001000">
        <property type="entry name" value="GH10_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490:SF76">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31490">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00331">
        <property type="entry name" value="Glyco_hydro_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00134">
        <property type="entry name" value="GLHYDRLASE10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00633">
        <property type="entry name" value="Glyco_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51760">
        <property type="entry name" value="GH10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0326">Glycosidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0624">Polysaccharide degradation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000429629" description="Endo-1,4-beta-xylanase 6">
        <location>
            <begin position="22"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="2">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="GH10" evidence="3">
        <location>
            <begin position="74"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="334"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="380" mass="40868" checksum="5723E7A41998CB6D" modified="2011-12-14" version="1" precursor="true">MRTPAIVLALAPAAAFGQAALWGQCGGQGWTGAKTCVSGAVCQAQNEWYSQCVPGSGGGNPPTPQPTQPSNPPPSTGSGLNAKFKNKGKLYFGTSMDHYDLNKAQLTNIVKAQFGQITNENSMKWDAIEPSRNSFSWTNADAVVNFATANGKLMRGHTLLWHSQLPAWVSNINDRNTLTQVIQNHVTAMVTRYRGKILQWDVVNEIFAEDGSLRSSVFSRVLGEDFVGIAFRAARAADPNAKLYINDYNLDIANYAKVTRGMVEKVNKWVSQGIPIDGIGSQAHLAQPGGWNPASGVPAALRALAAANVKEIAITELDIAGASANDYVTVVNACLQISKCVGITVWGVSDAISWRPNDNPLLYDRNYQPKAAYTAIMNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPR1</accession>
    <name>G4MPR1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_09205</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HRD1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709820.1">
        <property type="nucleotide sequence ID" value="XM_003709772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPR1"/>
    <dbReference type="STRING" id="242507.G4MPR1"/>
    <dbReference type="GeneID" id="2680288"/>
    <dbReference type="KEGG" id="mgr:MGG_09205"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09205"/>
    <dbReference type="eggNOG" id="KOG0802">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009169_1_1_1"/>
    <dbReference type="InParanoid" id="G4MPR1"/>
    <dbReference type="OMA" id="HILHFAC"/>
    <dbReference type="OrthoDB" id="7759664at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
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                <person name="Nicol R."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
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                <person name="Roberts A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    </reference>
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        <property type="nucleotide sequence ID" value="XM_003710636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPY4"/>
    <dbReference type="SMR" id="G4MPY4"/>
    <dbReference type="STRING" id="242507.G4MPY4"/>
    <dbReference type="GeneID" id="2676180"/>
    <dbReference type="KEGG" id="mgr:MGG_05759"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05759"/>
    <dbReference type="eggNOG" id="KOG2142">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010913_2_1_1"/>
    <dbReference type="InParanoid" id="G4MPY4"/>
    <dbReference type="OMA" id="WEWDRIF"/>
    <dbReference type="OrthoDB" id="10264306at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008265">
        <property type="term" value="F:molybdenum cofactor sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043545">
        <property type="term" value="P:molybdopterin cofactor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF80">
        <property type="entry name" value="MOLYBDENUM COFACTOR SULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="66"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="567" mass="62198" checksum="49D97A926E8AEF79" modified="2011-12-14" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ20</accession>
    <name>G4MQ20_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709025.1">
        <property type="nucleotide sequence ID" value="XM_003708977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQ20"/>
    <dbReference type="SMR" id="G4MQ20"/>
    <dbReference type="STRING" id="242507.G4MQ20"/>
    <dbReference type="GeneID" id="2681351"/>
    <dbReference type="KEGG" id="mgr:MGG_02254"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02254"/>
    <dbReference type="eggNOG" id="KOG1270">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_1_2_1"/>
    <dbReference type="InParanoid" id="G4MQ20"/>
    <dbReference type="OMA" id="PFLVCEG"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF3">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="27161" checksum="C0D387C41E6EC456" modified="2011-12-14" version="1">MASSLDVNNARFNAEAAEWDNNVKHVESTQKALDAISRHIPAFADGNAKDLDVLEIGCGTGLLSFLLAPHVRTLIGVDTASGMLSGFDAKLAALPDRAAANLTSVNVLLQDPDDAALQKAAADLDSRIAGSTAASRPRRFDLIVSHLTLHHIPSMPEIFATLAACLKPGGRVALTDYEDYGDEAIAFHPVTKREGVERHGIRRAEVVGAMRGAGLVDVGVEEAFVLRKEVEAEGGKPAREMDFPFLIMLGKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ69</accession>
    <name>G4MQ69_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709874.1">
        <property type="nucleotide sequence ID" value="XM_003709826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQ69"/>
    <dbReference type="STRING" id="242507.G4MQ69"/>
    <dbReference type="GeneID" id="2680260"/>
    <dbReference type="KEGG" id="mgr:MGG_09247"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09247"/>
    <dbReference type="HOGENOM" id="CLU_990698_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQ69"/>
    <dbReference type="OrthoDB" id="5242705at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35394:SF5">
        <property type="entry name" value="DUF3176 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="281" mass="31696" checksum="210860D2B83AD12B" modified="2011-12-14" version="1">MRAVEAPSATHTPGIEDQELLTSVGNDFSQRPPSKRWYEPECIWGLTSIFRSGLEQFMVEKINLHTLGLPTSAGEPWLRRSFQNGNASVATFDKVMEGLALAISGQMRSENVTANYFTPPVAGTAWENDTCIGVRWEWISFPATLILLEITLLLATIDRGRRSEWGGDWKSSSLPLLFNAPLNDKDMGASKSLKVADMEERASLLKFKLVQDSHESPSEGWRLHKVAELPPRKKKSRKDKKLSMEAQEPRTTVEQPEPLEDQSEPRVETRQNTVPRGHEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQA9</accession>
    <name>G4MQA9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA57302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003709866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQA9"/>
    <dbReference type="GeneID" id="12985291"/>
    <dbReference type="KEGG" id="mgr:MGG_16268"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16268"/>
    <dbReference type="HOGENOM" id="CLU_2373188_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQA9"/>
    <dbReference type="OrthoDB" id="10344282at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="95" mass="10686" checksum="52ED2C3E0ABA1D55" modified="2011-12-14" version="1">MGVVGRSQGFLHISEPLLKPGALIGMSPARRPWRSQYQNWKVSRQVERLPTLVRDMQLPADLTVPKLNNVSGSLLFCISCPAKEDRRLNFAALQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQD6</accession>
    <name>G4MQD6_PYRO7</name>
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            <fullName evidence="4">Glucan 1, 4-alpha-glucosidase</fullName>
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    <gene>
        <name evidence="2" type="ORF">MGG_10638</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710734.1">
        <property type="nucleotide sequence ID" value="XM_003710686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQD6"/>
    <dbReference type="STRING" id="242507.G4MQD6"/>
    <dbReference type="GeneID" id="2682233"/>
    <dbReference type="KEGG" id="mgr:MGG_10638"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10638"/>
    <dbReference type="eggNOG" id="ENOG502SBSC">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_022438_0_0_1"/>
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    <dbReference type="OMA" id="GARASFY"/>
    <dbReference type="OrthoDB" id="3941134at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="257"/>
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            <end position="545"/>
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            <begin position="564"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="53"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="110"/>
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            <begin position="168"/>
            <end position="192"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="728" mass="78977" checksum="5B5B63F5234BA182" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQR0</accession>
    <name>G4MQR0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57347.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_16279"/>
    <dbReference type="HOGENOM" id="CLU_1619362_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQR0"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="126"/>
            <end position="150"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="164" mass="17603" checksum="5E7EE9561C239D8D" modified="2011-12-14" version="1">MVGKAYTGTGSLQPGNRINCHFGHLHQRVSTFVGFKGPQALSKGWRSIVVIMYIKRYWVTDLERLAAYMLRSGRINIVLGTENVSGDPVVQPLGLPGLLTPAALRPAPVVCPGHSWIWSSFALSPKRSGATGGGPDERSPGLDPAPAPFPNDISLMRSWLGNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
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    <name>G4MQY6_PYRO7</name>
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        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
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    <gene>
        <name evidence="9" type="ORF">MGG_14575</name>
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
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        <property type="protein sequence ID" value="EHA56521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003709085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQY6"/>
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    <dbReference type="KEGG" id="mgr:MGG_14575"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14575"/>
    <dbReference type="eggNOG" id="ENOG502RSJA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019101_0_1_1"/>
    <dbReference type="InParanoid" id="G4MQY6"/>
    <dbReference type="OMA" id="NISTIWA"/>
    <dbReference type="OrthoDB" id="2988756at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="47"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="390"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="453"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="410"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="503"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="513" mass="56003" checksum="4C7FB16E95ECBB4C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR02</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">MGG_16110</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709149.1">
        <property type="nucleotide sequence ID" value="XM_003709101.1"/>
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    <dbReference type="GeneID" id="12984373"/>
    <dbReference type="KEGG" id="mgr:MGG_16110"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16110"/>
    <dbReference type="HOGENOM" id="CLU_2904640_0_0_1"/>
    <dbReference type="InParanoid" id="G4MR02"/>
    <dbReference type="OrthoDB" id="10418272at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="62" mass="6666" checksum="3A047F2024A106EF" modified="2011-12-14" version="1">MCRVRGVTGLGSSAAPMPVQGPIGDTNRLVCPSAKRDWAWAPMGPFLPRHSARSDAESVPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRC4</accession>
    <name>G4MRC4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16508</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710861.1">
        <property type="nucleotide sequence ID" value="XM_003710813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRC4"/>
    <dbReference type="GeneID" id="12986470"/>
    <dbReference type="KEGG" id="mgr:MGG_16508"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16508"/>
    <dbReference type="HOGENOM" id="CLU_2722687_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRC4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA58249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="72" mass="8047" checksum="3E539862A15C56CA" modified="2011-12-14" version="1">MAWKILRHPPPSSLDTLDVWSEDRKEVVMVMCSGKTEEKVTATVDGKNMSSNGDHFINHLEHLCSSTGLVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRV0</accession>
    <name>G4MRV0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02442</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709231.1">
        <property type="nucleotide sequence ID" value="XM_003709183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRV0"/>
    <dbReference type="SMR" id="G4MRV0"/>
    <dbReference type="FunCoup" id="G4MRV0">
        <property type="interactions" value="156"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRV0"/>
    <dbReference type="GeneID" id="2681539"/>
    <dbReference type="KEGG" id="mgr:MGG_02442"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02442"/>
    <dbReference type="eggNOG" id="KOG0961">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006065_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRV0"/>
    <dbReference type="OMA" id="CVEGPFW"/>
    <dbReference type="OrthoDB" id="4953at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000015">
        <property type="entry name" value="Putative zinc metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000031">
        <property type="entry name" value="Putative zinc metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000036">
        <property type="entry name" value="Putative zinc metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000042">
        <property type="entry name" value="Zinc metalloprotease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF16">
        <property type="entry name" value="METALLOPROTEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07610)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="2">
        <location>
            <begin position="60"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="3">
        <location>
            <begin position="198"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1053"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1053" mass="117650" checksum="38DFB4185016EF90" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSN2</accession>
    <name>G4MSN2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cystathionine beta-lyase</fullName>
            <ecNumber evidence="3">4.4.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cysteine-S-conjugate beta-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_07074</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L,L-cystathionine + H2O = L-homocysteine + pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13965"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:18121"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29256"/>
            <dbReference type="ChEBI" id="CHEBI:58717"/>
            <dbReference type="EC" id="4.4.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homocysteine from L-cystathionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.13" evidence="3"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715260.1">
        <property type="nucleotide sequence ID" value="XM_003715212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSN2"/>
    <dbReference type="SMR" id="G4MSN2"/>
    <dbReference type="FunCoup" id="G4MSN2">
        <property type="interactions" value="134"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSN2"/>
    <dbReference type="GeneID" id="2682959"/>
    <dbReference type="KEGG" id="mgr:MGG_07074"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07074"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_1_1"/>
    <dbReference type="InParanoid" id="G4MSN2"/>
    <dbReference type="OMA" id="NCIGATG"/>
    <dbReference type="OrthoDB" id="2545919at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047804">
        <property type="term" value="F:cysteine-S-conjugate beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000013">
        <property type="entry name" value="Cystathionine beta-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000009">
        <property type="entry name" value="Cystathionine gamma-synthase homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006238">
        <property type="entry name" value="Cys_b_lyase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01329">
        <property type="entry name" value="cysta_beta_ly_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF50">
        <property type="entry name" value="CYSTATHIONINE BETA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 13 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="13">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA55453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="454" mass="48726" checksum="6264F00F95DA722D" modified="2011-12-14" version="1">MAGQPSIPSAIGAKKALGLVDVDGHDLPPSPAPSSPSNGRRRYALATELVYTETKDQYGASSIPIYQSATFKQSSAAGGNSEYDYTRSGNPTRTHLERHMAKIMNANRALAVGSGMGALDVITRLLRPGDEVITGDDLYGGTNRLLTYLSANQGIIVHHIDTTDIDRVAATVSDKTAMVLLETPTNPLIKIVDVATIARAAHDRNSKALVVVDNTMLSPMLCNPLDLGADIVYESGTKYLSGHHDIMSGIVACNDAALADRMYFTVNATGCGLSPNDSFLLMRGIKTLAVRMEKQQANAQRIAEFLESHGFRVRYPGLKSHPQYDLHWSMARGAGAVLSFETGDAELSQRIVEAARLWAISVSFGCVNSLISMPCQMSHASIDAKTRKERQMPEDIIRLCVGIEDVQDLIDDLSRALVTAGAVSITVDGFHATGTALELGQTPLTTTKNDSPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSW3</accession>
    <name>G4MSW3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_04612</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713624.1">
        <property type="nucleotide sequence ID" value="XM_003713576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSW3"/>
    <dbReference type="SMR" id="G4MSW3"/>
    <dbReference type="FunCoup" id="G4MSW3">
        <property type="interactions" value="1121"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSW3"/>
    <dbReference type="GeneID" id="2677998"/>
    <dbReference type="KEGG" id="mgr:MGG_04612"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04612"/>
    <dbReference type="eggNOG" id="KOG3166">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055193_0_1_1"/>
    <dbReference type="InParanoid" id="G4MSW3"/>
    <dbReference type="OMA" id="RMVKWPA"/>
    <dbReference type="OrthoDB" id="29563at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001921">
        <property type="entry name" value="Ribosomal_eL8_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00882">
        <property type="entry name" value="RIBOSOMALL7A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="120"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA53817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="261" mass="29160" checksum="2E48D011CB795CE0" modified="2011-12-14" version="1">MPPKTGKKVAPAPFSAGKASKKAAKNPLLEKRSRNFGIGQDIQPRRNLSRMVKWPEYVRLQRQKKILSMRLKVPPALAQFQHVLDKNTAAQAFKLLNKYRPETKAEKKERLLKEATAVKEGKKKEDVSKKPYTAKYGLNHVVGLIENKKASLVLIPNDVDPVELVVFLPALCRKMGVPYAIIKGKARLGTVVHKKTAAVLAITEVRSEDKTELSKLISAIKDGYLEKSESARRTWGGGIMGYKAQQRELKKQKALDSAIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT66</accession>
    <name>G4MT66_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07141</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715338.1">
        <property type="nucleotide sequence ID" value="XM_003715290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT66"/>
    <dbReference type="STRING" id="242507.G4MT66"/>
    <dbReference type="GeneID" id="2683263"/>
    <dbReference type="KEGG" id="mgr:MGG_07141"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07141"/>
    <dbReference type="eggNOG" id="KOG2000">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006331_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT66"/>
    <dbReference type="OMA" id="DYCFHVG"/>
    <dbReference type="OrthoDB" id="775571at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF70">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="173"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="585"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="934" mass="104441" checksum="786430B46B005F2E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT71</accession>
    <name>G4MT71_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715343.1">
        <property type="nucleotide sequence ID" value="XM_003715295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT71"/>
    <dbReference type="GeneID" id="12985631"/>
    <dbReference type="KEGG" id="mgr:MGG_15864"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15864"/>
    <dbReference type="HOGENOM" id="CLU_2794437_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT71"/>
    <dbReference type="OMA" id="TKVQNSG"/>
    <dbReference type="OrthoDB" id="10392968at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="68" mass="7171" checksum="13E81213DE6FE7E1" modified="2011-12-14" version="1">MPAPPTEPPETWVRSVDHSKELNVVGPQALILGHNSVALKLSFLGSAKFGFEASAQNTKVQNSGIAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU09</accession>
    <name>G4MU09_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper-fist domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07205</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715416.1">
        <property type="nucleotide sequence ID" value="XM_003715368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU09"/>
    <dbReference type="SMR" id="G4MU09"/>
    <dbReference type="STRING" id="242507.G4MU09"/>
    <dbReference type="GeneID" id="2683093"/>
    <dbReference type="KEGG" id="mgr:MGG_07205"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07205"/>
    <dbReference type="eggNOG" id="ENOG502S7CA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022327_1_0_1"/>
    <dbReference type="InParanoid" id="G4MU09"/>
    <dbReference type="OMA" id="AHIKCDC"/>
    <dbReference type="OrthoDB" id="5600085at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:intracellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.430.10:FF:000001">
        <property type="entry name" value="Copper fist DNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.430.10">
        <property type="entry name" value="Copper fist DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051763">
        <property type="entry name" value="Copper_Homeo_Regul"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001083">
        <property type="entry name" value="Cu_fist_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036395">
        <property type="entry name" value="Cu_fist_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00649">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00617">
        <property type="entry name" value="COPPERFIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM01090">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00412">
        <property type="entry name" value="Cu_FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57879">
        <property type="entry name" value="Zinc domain conserved in yeast copper-regulated transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50073">
        <property type="entry name" value="COPPER_FIST_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Copper-fist" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="100"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="451" mass="48307" checksum="30DC6FD267542D06" modified="2011-12-14" version="1">MIIDGEKWACEACVRGHRVSNCQHSERPLQHINKKGRPVSQCQHCRSMRKSRASHVKCDCGEKTHKCAHLQPTLEGHRDSCCCNHGGRCSCSHKKDPPLLDPVPESDSDEPEKCASRTSSKAPSVKGTPRVRRRANTIHSDGKLSFDENGKHRPTYRHAKASSKCEPYPLKRVNSLQSASDGIRDTTVLTDSVDTSRKVKSETASPLLASGGVPSSFTQLNSSLRPLDLSVIQYPSYASQASQSTPCDALFSASLDYEPACFSAGLQPQIEWSQWDSLDFYADPVRDKFTPSSYDAHGGYSSASGFDFNGSDQAPTLATTTSGDVSEVEDFMGPSADDYDISSGFGNAVAMGTYGATGLLGAGSTGTGLSAYEIPDYTNEVPKSSQEGGLNGPKYIETPLDDGGLAAAGPIGAAFTEDALYWMPEVAPGIPPMADLSSVPEPNGLQWEGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU82</accession>
    <name>G4MU82_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peroxisomal dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04839</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713770.1">
        <property type="nucleotide sequence ID" value="XM_003713722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU82"/>
    <dbReference type="SMR" id="G4MU82"/>
    <dbReference type="STRING" id="242507.G4MU82"/>
    <dbReference type="GeneID" id="2678149"/>
    <dbReference type="KEGG" id="mgr:MGG_04839"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04839"/>
    <dbReference type="eggNOG" id="KOG1206">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040078_3_0_1"/>
    <dbReference type="InParanoid" id="G4MU82"/>
    <dbReference type="OMA" id="FKHTDQE"/>
    <dbReference type="OrthoDB" id="60204at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044594">
        <property type="term" value="F:17-beta-hydroxysteroid dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078:SF57">
        <property type="entry name" value="DEHYDRATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078">
        <property type="entry name" value="PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peroxisomal multifunctional enzyme type 2-like N-terminal" evidence="2">
        <location>
            <begin position="18"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="174"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="310" mass="33792" checksum="FDCC2342A029BAAA" modified="2011-12-14" version="1">MSGPGVGFEYPPTEVSWMKRDVLLFANSIGCKSDELHFLYELHPDFAVFPTYPVVLPFKTNTQEVIDFYAAQKSVTIPGVPEFDPTRVVDGQRRIEFLRPLPATSAGKRFEARTKVLGVYDKGRPGTVVETQTDLVDAGTGDVYTRATGSAFYVAQGNWGGPKGPATVNYPPPKGKTPDAVLEDATTLETPLLYRLNGDYNPLHATPEPGAKMGFGGVIVHGLWQWNSTCHQLLRHLGGSDPRNIKEYQARFASPVRPGVKLATSVWRTGKVEDGFEEIIFETKVVGGKTCLSNGRALIKVVGPAKGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV71</accession>
    <name>G4MV71_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleolar complex protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_08867</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713893.1">
        <property type="nucleotide sequence ID" value="XM_003713845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV71"/>
    <dbReference type="SMR" id="G4MV71"/>
    <dbReference type="FunCoup" id="G4MV71">
        <property type="interactions" value="1013"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MV71"/>
    <dbReference type="GeneID" id="2679853"/>
    <dbReference type="KEGG" id="mgr:MGG_08867"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08867"/>
    <dbReference type="eggNOG" id="KOG2256">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011272_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV71"/>
    <dbReference type="OMA" id="GCLRYYL"/>
    <dbReference type="OrthoDB" id="10266662at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042255">
        <property type="term" value="P:ribosome assembly"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="27"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="89"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="193"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="732"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="732"/>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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                <person name="Young S.K."/>
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                <person name="Abouelleil A."/>
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                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
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                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
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                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Abouelleil A."/>
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                <person name="Gearin G."/>
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                <person name="MacDonald P.J.P."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
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            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="328" mass="35342" checksum="777A6404F0926E6A" modified="2011-12-14" version="1">MSIAQFEEDKAQYVEQLEIVLSSLKDDPDSVELQALKEELESAISMIEESIAELRPKKTQAPPPPPPKAASPPPQPEKWRKEDHPAFKKAAAPEPAAPPPPPAAEEFQPDVTYQVNDNVLAKWMSGDKGFYPARITSVTGSSSARMYTVKFKSYGTVETLRSHDIKPVTAPAQKRKADGTPVNASGAAPLPPTGPPVPPSEPYGADASQPPPPPPQSAAAMRNSSGVVLSASPSLYPQKPQDGGEGAADAKPVKKFKKIKATKELEAGKNKWQDFNAKSKFGKSQKKDSMFRTPEGVHGRVGFTGSGQAMRKDASRSRHIYQPNEDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVV8</accession>
    <name>G4MVV8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_10812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715633.1">
        <property type="nucleotide sequence ID" value="XM_003715585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVV8"/>
    <dbReference type="STRING" id="242507.G4MVV8"/>
    <dbReference type="GeneID" id="2676330"/>
    <dbReference type="KEGG" id="mgr:MGG_10812"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10812"/>
    <dbReference type="eggNOG" id="ENOG502SNR8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_444863_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVV8"/>
    <dbReference type="OMA" id="CANDEED"/>
    <dbReference type="OrthoDB" id="5125733at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="156"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="614" mass="68592" checksum="8598E555F8A1552E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW14</accession>
    <name>G4MW14_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enterotoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713974.1">
        <property type="nucleotide sequence ID" value="XM_003713926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW14"/>
    <dbReference type="GeneID" id="2679926"/>
    <dbReference type="KEGG" id="mgr:MGG_08940"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08940"/>
    <dbReference type="HOGENOM" id="CLU_960013_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW14"/>
    <dbReference type="OrthoDB" id="10543595at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465686" description="Enterotoxin" evidence="2">
        <location>
            <begin position="23"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="32307" checksum="568CAB6BDF3E7938" modified="2011-12-14" version="1">MFYSVFVLAFTLLSLTPSLVAGVPAGFIYNNKLYVPSLLPPQEVRQNNGFVREGRNALALAYADKEVAYSEGLKRAEEKAGGNTNRETFYYYHIDTKNREDNFVLIKNQDTYDDRYKTEPWTRIFGAHRIPWEMIKGWTRNPPSPWPNVFVRKTNWEKKHPPGEYVAPERAPDSAPSSSRTPAQAPAPGRSVGQTHGLVPDYGPSSSRDAPPSRGGRPPSRAPPPQHEADVPSSSRAPARRPASARPYSEEIGYVAGPSSMLPEHHFPPWHPTPGMPPARRPPPPPGRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW82</accession>
    <name>G4MW82_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714849.1">
        <property type="nucleotide sequence ID" value="XM_003714801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW82"/>
    <dbReference type="SMR" id="G4MW82"/>
    <dbReference type="GeneID" id="2679207"/>
    <dbReference type="KEGG" id="mgr:MGG_01830"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01830"/>
    <dbReference type="HOGENOM" id="CLU_839574_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW82"/>
    <dbReference type="OMA" id="THELNSC"/>
    <dbReference type="OrthoDB" id="5228311at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="296"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="331" mass="36968" checksum="CACDBC5A343B99E3" modified="2011-12-14" version="1">MSTSDDALMRGATDRASYGDMSDGNVKRFHLSTVSAESRITRSDNLSLATPRRRRPATSTMAWLKTATECLIVNVNHYKAQRRLTKRRRAWVRSSQLGISPRVSTSHGQLPQQNTFQAVAVKIQKLASSSNQALSSNPATTADLKTVRRAKDRATLGGTSTAEKRRGRIFNSADIDYLGKALGEGPINCNGYSGPSATHELNSCQSLLVNRRSTESTAEEPRKRYSYWENQNRQNQAEIARLGAQADQLSRELSRLREVSQHNERFHRYYKRKYETTAHHLEGTMHALRLIDNVCGSSSRSESGDPGPPITDFDPATSPREHTYLQDVCGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWC9</accession>
    <name>G4MWC9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715696.1">
        <property type="nucleotide sequence ID" value="XM_003715648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWC9"/>
    <dbReference type="GeneID" id="2678537"/>
    <dbReference type="KEGG" id="mgr:MGG_08366"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08366"/>
    <dbReference type="eggNOG" id="ENOG502S35T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_882923_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWC9"/>
    <dbReference type="OMA" id="NNVCCPT"/>
    <dbReference type="OrthoDB" id="4779287at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="324" mass="34149" checksum="A050286472038DDC" modified="2011-12-14" version="1">MDDRFSHPQPSDPLAIFNVWAAQPDSCGYVGGWSLRVPSPGHCPAKASKPCGTGVQLRCCPPDLECRGADDYFGCYCCLPGEDCVPRVLEKPKCPTSEWSQWAINGTFEIGGFCCLPGLKGISIRLANNTFGFGCASPDATLAEYEGWAVEMPPSPCARVDSPASTTSPTGGLATSGPANDGLATGRIAGLVVGVILGVALVMAGAWFVLRKRRKGNGRGGDASKEGDSGDKTLAGAAAAGAAWPAERHFSQASTAVPHEMESQRWAHEMEDRSTVMPPELPPVTSMWRHNPDYEFVVVPSSTHSSTVSPLNRMGASPQGMPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWK7</accession>
    <name>G4MWK7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Beta-mannosidase B</fullName>
            <ecNumber evidence="5">3.2.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Mannanase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_01178</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; N-glycan degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase B subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="5"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714062.1">
        <property type="nucleotide sequence ID" value="XM_003714014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWK7"/>
    <dbReference type="SMR" id="G4MWK7"/>
    <dbReference type="STRING" id="242507.G4MWK7"/>
    <dbReference type="GeneID" id="2679279"/>
    <dbReference type="KEGG" id="mgr:MGG_01178"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01178"/>
    <dbReference type="eggNOG" id="KOG2230">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005015_1_1_1"/>
    <dbReference type="InParanoid" id="G4MWK7"/>
    <dbReference type="OMA" id="KRQWKGP"/>
    <dbReference type="OrthoDB" id="2866996at2759"/>
    <dbReference type="UniPathway" id="UPA00280"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004567">
        <property type="term" value="F:beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000118">
        <property type="entry name" value="Beta-mannosidase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000050">
        <property type="entry name" value="Beta-mannosidase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050887">
        <property type="entry name" value="Beta-mannosidase_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041447">
        <property type="entry name" value="Mannosidase_ig"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730:SF1">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17786">
        <property type="entry name" value="Mannosidase_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="18">
        <location>
            <begin position="14"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="15">
        <location>
            <begin position="199"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Mannosidase Ig/CBM-like" evidence="17">
        <location>
            <begin position="691"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase Ig-fold" evidence="16">
        <location>
            <begin position="791"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00041614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF17786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA54255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="858" mass="97876" checksum="7406A7427D6BF9EE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWP5</accession>
    <name>G4MWP5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714907.1">
        <property type="nucleotide sequence ID" value="XM_003714859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWP5"/>
    <dbReference type="GeneID" id="12985444"/>
    <dbReference type="KEGG" id="mgr:MGG_15785"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15785"/>
    <dbReference type="HOGENOM" id="CLU_2483788_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWP5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="87" mass="9779" checksum="2DBE3BF86467EA2C" modified="2011-12-14" version="1">MTDGKGKKSSGKLQLQLLPNALIDSLFIRSGWLNKLRLCQVTRALNYCTKTSQRPEMISTLQRQATAKLHEDHHGELENVVPQAKPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWQ7</accession>
    <name>G4MWQ7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714919.1">
        <property type="nucleotide sequence ID" value="XM_003714871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWQ7"/>
    <dbReference type="SMR" id="G4MWQ7"/>
    <dbReference type="GeneID" id="12985449"/>
    <dbReference type="KEGG" id="mgr:MGG_15786"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15786"/>
    <dbReference type="HOGENOM" id="CLU_2996922_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWQ7"/>
    <dbReference type="OrthoDB" id="3794568at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="57" mass="6696" checksum="D59C8E4E97849859" modified="2011-12-14" version="1">MGKKRTAEDRRKQAEESGFNFDDEDVDDKPVPRFVLGYTERVCNVQVELWQDILKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWW5</accession>
    <name>G4MWW5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrogen metabolic regulation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_12473</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715776.1">
        <property type="nucleotide sequence ID" value="XM_003715728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWW5"/>
    <dbReference type="SMR" id="G4MWW5"/>
    <dbReference type="STRING" id="242507.G4MWW5"/>
    <dbReference type="GeneID" id="5051067"/>
    <dbReference type="KEGG" id="mgr:MGG_12473"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12473"/>
    <dbReference type="eggNOG" id="ENOG502QTW1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027360_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWW5"/>
    <dbReference type="OMA" id="LWEGWRD"/>
    <dbReference type="OrthoDB" id="5356836at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF5">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="125"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="476"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA55969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="532" mass="59740" checksum="BFDA66EE70A91FA3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXF2</accession>
    <name>G4MXF2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar sorting protein Vps3844 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_10742</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713289.1">
        <property type="nucleotide sequence ID" value="XM_003713241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXF2"/>
    <dbReference type="GeneID" id="2676247"/>
    <dbReference type="KEGG" id="mgr:MGG_10742"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10742"/>
    <dbReference type="eggNOG" id="ENOG502S64Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054960_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXF2"/>
    <dbReference type="OMA" id="DVSVPFW"/>
    <dbReference type="OrthoDB" id="5583277at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053065">
        <property type="entry name" value="Archenteron_Induction-Rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024382">
        <property type="entry name" value="Vps3844_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853:SF1">
        <property type="entry name" value="DUF3844 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36853">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12955">
        <property type="entry name" value="Vps3844_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465458" description="Vacuolar sorting protein Vps3844 C-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar sorting protein Vps3844 C-terminal" evidence="4">
        <location>
            <begin position="288"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA53482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="407" mass="43479" checksum="A58B0E96381A8EA6" modified="2011-12-14" version="1">MKWCTKTFASLSLAGLALASSGNRFETDAEAFILSANHDASSARPRLPPQLVRHILLQRVSTGDDHSSLSADLPDEIETDRALAYLNQYGREPRALFSRSKDEDRNPSMVLMLEGITEDNGKALRQGLKARKQALAFTVADMPSADATAELLQRDFSGLLSSCDELADLATPENDKCWSGRALVAKHDVAKNPEFLSSLTSNLDTLLAATTKKHMDVMILLVPESSRTAGVKEWTSATNTLNRRQASEAVITDPRANEHSAKATGHKKQPVSSSSSASTAALRKIPTCFSSASACMNATDSCSGHGACHNRFSADDNKPETSADNKALVCFHCVCAPTINDDKGVQSRTFWAGNTCAKQDVSTQFWLIAGSTVALVGLVSLSVGMLFSVGEEKLPGVIGAGVSKSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXG9</accession>
    <name>G4MXG9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713306.1">
        <property type="nucleotide sequence ID" value="XM_003713258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXG9"/>
    <dbReference type="GeneID" id="12986169"/>
    <dbReference type="KEGG" id="mgr:MGG_15410"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15410"/>
    <dbReference type="HOGENOM" id="CLU_1949240_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXG9"/>
    <dbReference type="OrthoDB" id="10278638at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466284" evidence="1">
        <location>
            <begin position="19"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="129" mass="14135" checksum="9C07D78D05E1DF34" modified="2011-12-14" version="1">MQFPSALIFGLLIQSAVAEPGHVSQQPGGCPAGQTTRINGQCPTGHLSRRHGAKYCPTRRWSYRWIGGFGVLSTFRLVFLTASSYGVRIRPMDLLRPARPPKNGQYDFPEVSVLSRGPPCWITPPDGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXT7</accession>
    <name>G4MXT7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_08252</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715834.1">
        <property type="nucleotide sequence ID" value="XM_003715786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXT7"/>
    <dbReference type="SMR" id="G4MXT7"/>
    <dbReference type="GeneID" id="2678473"/>
    <dbReference type="KEGG" id="mgr:MGG_08252"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08252"/>
    <dbReference type="eggNOG" id="ENOG502QU6S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024407_1_0_1"/>
    <dbReference type="InParanoid" id="G4MXT7"/>
    <dbReference type="OMA" id="TWAITLC"/>
    <dbReference type="OrthoDB" id="1288932at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562">
        <property type="entry name" value="NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43562:SF3">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="529"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="41"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="289"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="427"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="302"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="430"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA56027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="581" mass="61403" checksum="665556F623070106" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY14</accession>
    <name>G4MY14_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="8">PPIase</shortName>
            <ecNumber evidence="8">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_10447</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="8"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713349.1">
        <property type="nucleotide sequence ID" value="XM_003713301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY14"/>
    <dbReference type="SMR" id="G4MY14"/>
    <dbReference type="STRING" id="242507.G4MY14"/>
    <dbReference type="GeneID" id="2682080"/>
    <dbReference type="KEGG" id="mgr:MGG_10447"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10447"/>
    <dbReference type="eggNOG" id="KOG0865">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_12_0_1"/>
    <dbReference type="InParanoid" id="G4MY14"/>
    <dbReference type="OMA" id="ENFKRTH"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="PHI-base" id="PHI:7734"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000032">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF385">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="9">
        <location>
            <begin position="68"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="215" mass="23553" checksum="1898390D2E3BD982" modified="2011-12-14" version="1">MRTTLLRPLVPRQNIFSSSIPRTSFVKPNFVATPKSPINNTTRVRFYSSTMSKPNVFFDISFNGVTKRVEFKLYDDVVPKTADNFRRLCVGEPGVGGYKDSGFHRIIPDFMLQGGDFTRGNGTGGKSVYGEKFADENFQIKHTRPGLLSMANAGPNTNGSQFFITTVKTSWLDGKHVVFGEVVSGFEDVIKPIEALGSSSGTPKTKVTIVNAGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ70</accession>
    <name>G4MZ70_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U3 small nucleolar RNA-associated protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08178</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ASTRA complex involved in chromatin remodeling.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715150.1">
        <property type="nucleotide sequence ID" value="XM_003715102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ70"/>
    <dbReference type="SMR" id="G4MZ70"/>
    <dbReference type="FunCoup" id="G4MZ70">
        <property type="interactions" value="1044"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZ70"/>
    <dbReference type="GeneID" id="2678414"/>
    <dbReference type="KEGG" id="mgr:MGG_08178"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08178"/>
    <dbReference type="eggNOG" id="KOG0319">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009276_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ70"/>
    <dbReference type="OMA" id="PYVQRHF"/>
    <dbReference type="OrthoDB" id="5414888at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001009">
        <property type="entry name" value="Small nucleolar ribonucleoprotein complex subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013934">
        <property type="entry name" value="Utp13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF15">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08625">
        <property type="entry name" value="Utp13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="107"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="224"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="272"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="414"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="527"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="603"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="658"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 13 C-terminal" evidence="7">
        <location>
            <begin position="757"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA55343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="942" mass="101810" checksum="A1E59BC6EC7C059D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ96</accession>
    <name>G4MZ96_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cutinase transcription factor 1 beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_08199</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715176.1">
        <property type="nucleotide sequence ID" value="XM_003715128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ96"/>
    <dbReference type="STRING" id="242507.G4MZ96"/>
    <dbReference type="GeneID" id="2678434"/>
    <dbReference type="KEGG" id="mgr:MGG_08199"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08199"/>
    <dbReference type="eggNOG" id="ENOG502RHAD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006329_1_1_1"/>
    <dbReference type="InParanoid" id="G4MZ96"/>
    <dbReference type="OMA" id="WDNVECI"/>
    <dbReference type="OrthoDB" id="4451586at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052761">
        <property type="entry name" value="Fungal_Detox/Toxin_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47425:SF2">
        <property type="entry name" value="FARB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="891"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="960"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="913"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="998"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA55369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1009" mass="109952" checksum="E33344A1F0A14BE4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ98</accession>
    <name>G4MZ98_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA55371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003715130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ98"/>
    <dbReference type="SMR" id="G4MZ98"/>
    <dbReference type="STRING" id="242507.G4MZ98"/>
    <dbReference type="GeneID" id="2678435"/>
    <dbReference type="KEGG" id="mgr:MGG_08200"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08200"/>
    <dbReference type="eggNOG" id="KOG4157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004824_1_0_1"/>
    <dbReference type="InParanoid" id="G4MZ98"/>
    <dbReference type="OMA" id="HDMSTAN"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="PHI-base" id="PHI:5186"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000020">
        <property type="entry name" value="Peroxisomal ascorbate peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF53">
        <property type="entry name" value="HEME PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465556" description="WSC domain-containing protein" evidence="5">
        <location>
            <begin position="23"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="6">
        <location>
            <begin position="125"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="7">
        <location>
            <begin position="588"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="7">
        <location>
            <begin position="711"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA55371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="804" mass="84114" checksum="2BBC563FD14C342D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZE5</accession>
    <name>G4MZE5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713507.1">
        <property type="nucleotide sequence ID" value="XM_003713459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZE5"/>
    <dbReference type="STRING" id="242507.G4MZE5"/>
    <dbReference type="GeneID" id="12987106"/>
    <dbReference type="KEGG" id="mgr:MGG_15537"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15537"/>
    <dbReference type="eggNOG" id="ENOG502S12V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019479_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZE5"/>
    <dbReference type="OMA" id="WPVIVCD"/>
    <dbReference type="OrthoDB" id="62853at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026093">
        <property type="entry name" value="MGARP"/>
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    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN MGARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22910:SF6">
        <property type="entry name" value="PROTEIN MGARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="2">
        <location>
            <begin position="188"/>
            <end position="261"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="549"/>
            <end position="650"/>
        </location>
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            <begin position="1"/>
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        </location>
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            <begin position="330"/>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        </location>
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        <location>
            <begin position="625"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA53700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="650" mass="69379" checksum="460BABF61E9CA3F5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZW2</accession>
    <name>G4MZW2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15188</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
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    </dbReference>
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    <dbReference type="KEGG" id="mgr:MGG_15188"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15188"/>
    <dbReference type="HOGENOM" id="CLU_1441316_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZW2"/>
    <dbReference type="OrthoDB" id="4152607at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="188" mass="21246" checksum="EFCAF7645CE254AB" modified="2011-12-14" version="1">MALDLDSAINVFGFLSISQDALLFNPSKDQNSIRRGLHDVPPYLFRVHTPKSAGTLDEEWARSEDAKAALTDPTRRESSETDILQRRDFNHVAKDISAHLWQQTESGLRLDEIKLCIVRTGGLRAGTFLRDAYLLDFYSKCDLPVPGAKDSQSLVDMKSMRNKGWYFGEYLSQDSLKTTERCSIVSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1F3</accession>
    <name>G4N1F3_PYRO7</name>
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        <submittedName>
            <fullName evidence="4">2-nitropropane dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09511</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712231.1">
        <property type="nucleotide sequence ID" value="XM_003712183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1F3"/>
    <dbReference type="SMR" id="G4N1F3"/>
    <dbReference type="STRING" id="242507.G4N1F3"/>
    <dbReference type="GeneID" id="2680519"/>
    <dbReference type="KEGG" id="mgr:MGG_09511"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09511"/>
    <dbReference type="eggNOG" id="ENOG502QQW7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038732_1_0_1"/>
    <dbReference type="InParanoid" id="G4N1F3"/>
    <dbReference type="OMA" id="IDDLPSC"/>
    <dbReference type="OrthoDB" id="412383at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF28">
        <property type="entry name" value="DIOXYGENASE FAMILY OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="329" mass="35229" checksum="CD95BF717CA3E288" modified="2011-12-14" version="1">MPFNTELTRKLGIKIPVVQGGMMHVGYASLASAVSNAGGLGIITALIFPTPEGLREEIRKCRTMTDKPFGVNLTLLPSMVPPDYPAYVRVVVEEGIKVVETAGNSPGPVIAALKKAGIIVLHKCTSIRHAESAVKMGVDFLSIDGFECAGHVGESDITNFILLSRARQKLKVPFIASGGFADGQGLAAALCLGASGINMGTRFMCTVEAPIHNNIKETIVGASEHDTALVLRSFRNTTRLYRNKVTEEAIKAEKGANGDFSQLAPLVSGQRGKQVFINGDPDYGVWTAGQVIGLIHDIPTCDVLLKRIEKEAEDSLKEKLSMTNLDSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1R1</accession>
    <name>G4N1R1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Imidazoleglycerol-phosphate dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711440.1">
        <property type="nucleotide sequence ID" value="XM_003711392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1R1"/>
    <dbReference type="GeneID" id="2683447"/>
    <dbReference type="KEGG" id="mgr:MGG_07527"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07527"/>
    <dbReference type="eggNOG" id="ENOG502SG61">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148205_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1R1"/>
    <dbReference type="OMA" id="YLQMSGM"/>
    <dbReference type="OrthoDB" id="3979469at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038882">
        <property type="entry name" value="Rcf3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39153">
        <property type="entry name" value="AGR244WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39153:SF1">
        <property type="entry name" value="AGR244WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15130" checksum="51F53A72310982F8" modified="2011-12-14" version="1">MSRYDVLRREEAVGAGRAAAQAGVIGAARWGVGFAILGGLGYAISPIYRGLTIQFKTYIQMSGMVFGGMIEADRGLRRFEAEQRSRRRAARNQVAWEAYEKELRALEGEEDMNFPDQRQSTKGIEPPSKPGDASDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1T6</accession>
    <name>G4N1T6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_09488</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712258.1">
        <property type="nucleotide sequence ID" value="XM_003712210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1T6"/>
    <dbReference type="SMR" id="G4N1T6"/>
    <dbReference type="GeneID" id="2680559"/>
    <dbReference type="KEGG" id="mgr:MGG_09488"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09488"/>
    <dbReference type="eggNOG" id="ENOG502T3C8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1245593_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1T6"/>
    <dbReference type="OMA" id="RSWIGEP"/>
    <dbReference type="OrthoDB" id="2146436at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF1">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465834" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="9">
        <location>
            <begin position="20"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="10">
        <location>
            <begin position="23"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA52451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="222" mass="24049" checksum="1E027E1D99E83FC8" modified="2011-12-14" version="1">MLLNPILLIAGLGAGVSSAYHLLRLPNSMGYKRDWAHRSPCSNFNISQVMVGTNYSVNGYPLAVTSTYANVTFTVRVRLLNDSAEEKFHQILPPLVMSMYGTLCIPSVPVDKNWAGQLAQYQVISDHASMRTYQCSLVQFVDTPAVDASSFDVCKNTTGVNGTFQEWGSEILTTPTPSSAPPAPTEVEPENAAQDNKAKLNPWMVVGVPAVTGLLPILATLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1Y0</accession>
    <name>G4N1Y0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_13884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713097.1">
        <property type="nucleotide sequence ID" value="XM_003713049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1Y0"/>
    <dbReference type="SMR" id="G4N1Y0"/>
    <dbReference type="GeneID" id="5049380"/>
    <dbReference type="KEGG" id="mgr:MGG_13884"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13884"/>
    <dbReference type="HOGENOM" id="CLU_1378380_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1Y0"/>
    <dbReference type="OrthoDB" id="5231740at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="20261" checksum="E18E933213FF380D" modified="2011-12-14" version="1">MSVTRISWVPIKAGVDDAALAPLTAAGAALAKQPGIESIYHGPWDSVDAAKAAESSSAFSEIEGILAGVIDTSGAQPYTNLVSLNKPFSSIVSPVTRIIAIILPATVDKAAFAAELEASIATAETPGFKGAVYGWAADRMEHPSVPGGPANIFVALAGWDSVESSKASESAPGMADHQAALAKFGGVFEVHYVPLEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N206</accession>
    <name>G4N206_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_07882</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713123.1">
        <property type="nucleotide sequence ID" value="XM_003713075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N206"/>
    <dbReference type="SMR" id="G4N206"/>
    <dbReference type="GeneID" id="2683809"/>
    <dbReference type="KEGG" id="mgr:MGG_07882"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07882"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="InParanoid" id="G4N206"/>
    <dbReference type="OMA" id="MGVRQPN"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF130">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="414"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="90"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="477" mass="50735" checksum="A0F99C58E0797E37" modified="2011-12-14" version="1">MNNHPPETTGPTSQTAGDRRPSVQSIETDIISPASPALHDLEKATTGPKKSSELHKSLSNVLSRAATHLTTRSLPEPPPPPDGGLRAWSQVACAWLVIFVTWGQVNAFGAFQTYYTEALAPLSPSVVSWIGAVQVWLTFFVGAFSGRLLDAGFFRPTVVVGAVVQLLGLFLISASTRFWQLMLTQGVLVGVGSGIVFTPSMGLLSTYFVKRRAVAIGLATSGNAVGGLVYPLIVRQLLPAVGFAWTVRVVAFVNLVCLGIAVVFMRPRLPPRKSGPLIDFDAFREPVYVGIVTGLFFVMWGTYYTIYYIGSYGTQALGLPYSTAAITVIVVNAAGLLPRIIVPFVAARYGAINTAVPTTAIFAIVAFTWLAVRSEPGYYAFATVYGMSNGAFHCIMPTVIASITPRLDMVGTRLGMAFSIIGFAALTGPPIGGALQGAMGGNFMGASVWAAMSMVVCLGFISFARWRLAGFDLGAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2N2</accession>
    <name>G4N2N2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Allantoin permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_04864</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712344.1">
        <property type="nucleotide sequence ID" value="XM_003712296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2N2"/>
    <dbReference type="SMR" id="G4N2N2"/>
    <dbReference type="GeneID" id="2675524"/>
    <dbReference type="KEGG" id="mgr:MGG_04864"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04864"/>
    <dbReference type="eggNOG" id="KOG2466">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021555_2_1_1"/>
    <dbReference type="InParanoid" id="G4N2N2"/>
    <dbReference type="OMA" id="SICLRCI"/>
    <dbReference type="OrthoDB" id="2018619at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11482">
        <property type="entry name" value="SLC-NCS1sbd_NRT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045225">
        <property type="entry name" value="Uracil/uridine/allantoin_perm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618">
        <property type="entry name" value="NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30618:SF0">
        <property type="entry name" value="PURINE-URACIL PERMEASE NCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="148"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="225"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="551" mass="60226" checksum="0C041334AEF52E2B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N396</accession>
    <name>G4N396_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_10846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003713200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N396"/>
    <dbReference type="SMR" id="G4N396"/>
    <dbReference type="GeneID" id="2676378"/>
    <dbReference type="KEGG" id="mgr:MGG_10846"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10846"/>
    <dbReference type="HOGENOM" id="CLU_1547908_0_0_1"/>
    <dbReference type="InParanoid" id="G4N396"/>
    <dbReference type="OrthoDB" id="5237720at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="173" mass="20488" checksum="F01053A17D234C0D" modified="2011-12-14" version="1">MSLEDETDNLESILDRIKEGFLEMKTALQDVQDLNTRLRDTYVWCEKMNKECKQSMTTDESWCTETREHRLDMINQSLQDLQRLEEMPHWVFQQWPVLRAHVGSLDESPCISARRRLGIQAHMDEQQRLIDDGVEEIYHLCATIRYKTVETVDMLEQPTEEELKAEELVESAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3M2</accession>
    <name>G4N3M2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epoxide hydrolase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05826</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711653.1">
        <property type="nucleotide sequence ID" value="XM_003711605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3M2"/>
    <dbReference type="SMR" id="G4N3M2"/>
    <dbReference type="STRING" id="242507.G4N3M2"/>
    <dbReference type="ESTHER" id="mago7-a4qx26">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="GeneID" id="2684149"/>
    <dbReference type="KEGG" id="mgr:MGG_05826"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05826"/>
    <dbReference type="eggNOG" id="KOG4178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_2_1"/>
    <dbReference type="InParanoid" id="G4N3M2"/>
    <dbReference type="OMA" id="EFGQWDY"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="30"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="357" mass="39500" checksum="849D551A802F29DB" modified="2011-12-14" version="1">MSSLTLRENAFEHSGDKTTFYWSAGPSNGPLVILIHGWPANGETWKPQLLALGGLGFHAVAPDTRGYGRSSVPAGPEAYALEHHVSDMVALLAHLRRDKAVWIGHDWGAGLVWAFAAMQPDKCVGVCCLTVPYAVLGQGIELLASLSNRDIYPEDKFPYAQWDYMAFHNEQPEASAAQLAANVPNTVKTLYRAGSPETYRKPAFSAMMRKMGGWFGSPTAGAPDVPLEATLFAQDEPAYERMVAEFQKNGFEAPNDYYRNFDKNSEYLAKAPNGGRLAFPVLFIGAQWDSIVDTTISRLAEPMRELCDDLTEVTIEAGHWVAMEKPQETNAALVRWLVTKLPRHYPGYWKTPFVSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3R3</accession>
    <name>G4N3R3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Exo-beta-D-glucosaminidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_05864</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711694.1">
        <property type="nucleotide sequence ID" value="XM_003711646.1"/>
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    <dbReference type="AlphaFoldDB" id="G4N3R3"/>
    <dbReference type="SMR" id="G4N3R3"/>
    <dbReference type="STRING" id="242507.G4N3R3"/>
    <dbReference type="CAZy" id="GH2">
        <property type="family name" value="Glycoside Hydrolase Family 2"/>
    </dbReference>
    <dbReference type="GeneID" id="2684111"/>
    <dbReference type="KEGG" id="mgr:MGG_05864"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05864"/>
    <dbReference type="eggNOG" id="KOG2230">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005015_2_4_1"/>
    <dbReference type="InParanoid" id="G4N3R3"/>
    <dbReference type="OMA" id="AWPNLHW"/>
    <dbReference type="OrthoDB" id="408532at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043534">
        <property type="entry name" value="EBDG/EBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041351">
        <property type="entry name" value="Ig_GlcNase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041447">
        <property type="entry name" value="Mannosidase_ig"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536">
        <property type="entry name" value="MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536:SF1">
        <property type="entry name" value="MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18368">
        <property type="entry name" value="Ig_GlcNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17786">
        <property type="entry name" value="Mannosidase_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="11">
        <location>
            <begin position="111"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="8">
        <location>
            <begin position="272"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Mannosidase Ig/CBM-like" evidence="9">
        <location>
            <begin position="752"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="domain" description="Exo-beta-D-glucosaminidase Ig-fold" evidence="10">
        <location>
            <begin position="846"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA51887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="956" mass="104987" checksum="562E0392C3E5972F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3W5</accession>
    <name>G4N3W5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712545.1">
        <property type="nucleotide sequence ID" value="XM_003712497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3W5"/>
    <dbReference type="GeneID" id="2675413"/>
    <dbReference type="KEGG" id="mgr:MGG_05037"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05037"/>
    <dbReference type="HOGENOM" id="CLU_866497_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3W5"/>
    <dbReference type="OrthoDB" id="2142213at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465957" description="Conidiation-specific protein 13" evidence="1">
        <location>
            <begin position="23"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="35727" checksum="945548D07BDB0700" modified="2011-12-14" version="1">MFFDNFIPAMATMAALSGLALAVENFKPTIKPMAFDMYGMDKDLRLHMPPMSISDIKVESWIPGKIPYACFNGEGLEGTFAMTTINPWEFHVFNVTFKDCDRSWVVCRHYNAGATELEVVKGISAMPVGIREAVSVFTAVPLNMPGGVAAWVHDGDTMVVQDPIYWSSPYLLMHEATHALDWTTLSPAPFDRFWSYGDEWRAAIDSDGVVPSVYAANAAGPEQFNLREDFAEVGGIALYDLNVPGGIDGFHKNASAISAQLALYKKVVGEARIVKGGRCSAAKAEVRRIVDIAGFKDDDVVGEADATKMADHDLTVPPVEPLLSQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5M2</accession>
    <name>G4N5M2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712022.1">
        <property type="nucleotide sequence ID" value="XM_003711974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5M2"/>
    <dbReference type="GeneID" id="5049066"/>
    <dbReference type="KEGG" id="mgr:MGG_13198"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13198"/>
    <dbReference type="eggNOG" id="ENOG502SX2P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_163539_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5M2"/>
    <dbReference type="OMA" id="FFAYQQG"/>
    <dbReference type="OrthoDB" id="5232608at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466047" evidence="1">
        <location>
            <begin position="17"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="89" mass="9598" checksum="D84BF669D297569D" modified="2011-12-14" version="1">MIEALVVCLLFIIAVATLYYAYEQGHLDPYIEQVGTYLFKAKAMAEKKRLQAQGMKAGQDFVDSQLAGAQQADQVKAGVGAIGGLKKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5Y4</accession>
    <name>G4N5Y4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_03122</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CHS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716879.1">
        <property type="nucleotide sequence ID" value="XM_003716831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5Y4"/>
    <dbReference type="FunCoup" id="G4N5Y4">
        <property type="interactions" value="48"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5Y4"/>
    <dbReference type="GeneID" id="2676905"/>
    <dbReference type="KEGG" id="mgr:MGG_03122"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03122"/>
    <dbReference type="eggNOG" id="ENOG502QRVH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050424_1_1_1"/>
    <dbReference type="InParanoid" id="G4N5Y4"/>
    <dbReference type="OMA" id="TVWEVKD"/>
    <dbReference type="OrthoDB" id="2189463at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF2">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA50560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="332" mass="37073" checksum="6692A4488690E8CB" modified="2011-12-14" version="1">MPGFGDFTSLCQMAPLPLCSNVGKVNNIIGIEPNCYARSIELANTIIFQGAASAMHIVALCMTVVMVLHVRGKFTAVGRKEILNFFYFYMLLTFISLCVDAGVVPPGSGPYPYFVSVQNGLTSSLVTCLLINGFVGFQLYEDGTPLSLWMMRICSIVAFAITFLVSLATFKSWVGLSPSNTIGLFVVLYLLNAVQLFVYVVLQVMLVVRTLHERWPLGDIAFGVFFFVLGQVILYALSTPICEAVSHYMDGLFFATTCNLLGVMMVYKYWDSITKEDLEFSVGTRMNNWEVKELLPEEDRRQTIYTEDPYGQSSGYDHPYSPNTAARPYSKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6C3</accession>
    <name>G4N6C3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="2">2.7.1.68</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-phosphatidylinositol 4-phosphate kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diphosphoinositide kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">PIP5K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_06572</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14425"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.68"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.1.68" evidence="2"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716964.1">
        <property type="nucleotide sequence ID" value="XM_003716916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6C3"/>
    <dbReference type="SMR" id="G4N6C3"/>
    <dbReference type="STRING" id="242507.G4N6C3"/>
    <dbReference type="GeneID" id="2684727"/>
    <dbReference type="KEGG" id="mgr:MGG_06572"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06572"/>
    <dbReference type="eggNOG" id="KOG0229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004312_0_3_1"/>
    <dbReference type="InParanoid" id="G4N6C3"/>
    <dbReference type="OMA" id="DENHANW"/>
    <dbReference type="OrthoDB" id="20783at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <dbReference type="PubMed" id="15846337"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference key="2">
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="MacDonald P.J.P."/>
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                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification.</text>
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    <dbReference type="KEGG" id="mgr:MGG_03562"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03562"/>
    <dbReference type="eggNOG" id="KOG0280">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036100_1_0_1"/>
    <dbReference type="InParanoid" id="G4N7M9"/>
    <dbReference type="OMA" id="LDMKWLP"/>
    <dbReference type="OrthoDB" id="1930760at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061685">
        <property type="term" value="F:diphthine methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052415">
        <property type="entry name" value="Diphthine_MTase"/>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042:SF1">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA50034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="443" mass="48104" checksum="0E6CC6A4FB5342AB" modified="2011-12-14" version="1">MAEDEGTIIKSLTSVQLPMEPACLEFCPAHPEYLIIGSWHLIKDDHHDGTQAREQDEGDGPAGDHQGVSASDKQRHMGRVDLYRIQGEQVDLVQTDEYPESAIWDVQFQKRNGRADVFAAGSSAGTVFIYKVTAPSSSADNADAALRRLSIVGPISGEEDGEVMITKCYWHPMIPDLLAVSTLAGEVHLIWLDGKDDLFTPLSVTRVSALAHSEPAWTVALSPQVATPEGTDDRVFTVYSGGDDMAFRYASVAMRGAVPPAEGAAAPPEFDDALFSPAKKSWHMAGVVSILPLPITLPSDGSQIVVTGSYDDHVRVCAVRPLHETYGMATARVLTELHLGGGAWRLRVMEMIADPSGSSWRLRILTPCMSVGSRVLEICGADDSQEWTIKVLGSWWEEAAGASMLNYGSDVQPRREGASGGGDDKFTCVSSNFYGKMLYLWKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7N2</accession>
    <name>G4N7N2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SPIN90/Ldb17 leucine-rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716356.1">
        <property type="nucleotide sequence ID" value="XM_003716308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7N2"/>
    <dbReference type="FunCoup" id="G4N7N2">
        <property type="interactions" value="8"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7N2"/>
    <dbReference type="GeneID" id="2676698"/>
    <dbReference type="KEGG" id="mgr:MGG_03559"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03559"/>
    <dbReference type="eggNOG" id="KOG4035">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017272_0_1_1"/>
    <dbReference type="InParanoid" id="G4N7N2"/>
    <dbReference type="OMA" id="ISLRHTY"/>
    <dbReference type="OrthoDB" id="445362at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000147">
        <property type="term" value="P:actin cortical patch assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030125">
        <property type="entry name" value="SPIN90/Ldb17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018556">
        <property type="entry name" value="SPIN90/Ldb17_LRD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357:SF1">
        <property type="entry name" value="NCK-INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13357">
        <property type="entry name" value="SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09431">
        <property type="entry name" value="SPIN90_LRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPIN90/Ldb17 leucine-rich" evidence="2">
        <location>
            <begin position="189"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="537" mass="60215" checksum="FF2600046A001954" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7R3</accession>
    <name>G4N7R3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716387.1">
        <property type="nucleotide sequence ID" value="XM_003716339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7R3"/>
    <dbReference type="STRING" id="242507.G4N7R3"/>
    <dbReference type="GeneID" id="2676909"/>
    <dbReference type="KEGG" id="mgr:MGG_03531"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03531"/>
    <dbReference type="eggNOG" id="ENOG502S3QT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_434770_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7R3"/>
    <dbReference type="OMA" id="WASSAIN"/>
    <dbReference type="OrthoDB" id="5590473at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18724">
        <property type="entry name" value="PIN_LabA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007681">
        <property type="entry name" value="Mog1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837:SF5">
        <property type="entry name" value="NYN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="571" mass="63802" checksum="2DB8138C666AEFBD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N890</accession>
    <name>G4N890_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716456.1">
        <property type="nucleotide sequence ID" value="XM_003716408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N890"/>
    <dbReference type="SMR" id="G4N890"/>
    <dbReference type="GeneID" id="2676811"/>
    <dbReference type="KEGG" id="mgr:MGG_03469"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03469"/>
    <dbReference type="eggNOG" id="ENOG502ST0G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117761_0_0_1"/>
    <dbReference type="InParanoid" id="G4N890"/>
    <dbReference type="OMA" id="VNPKFWG"/>
    <dbReference type="OrthoDB" id="5334244at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="193" mass="20187" checksum="BC27C27DF59297C7" modified="2011-12-14" version="1">MQRLSVLRLKALSQPSSTVYTSPTIPIHLHLQAQSALARNRMPIASNTTAKLASTSSAPKSAEGPSAQSGGSRSKDAAEAAEARGDKPSSSSSSADPETAGIDSLSERDALGRTGGGKPLESSSENAPPPPKVNNSSIPGDGRGKLSKEQKQEVDEHNREFEERHDRASPASKDKVNKSFWSGGGTRKSPGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8F1</accession>
    <name>G4N8F1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable enoyl-CoA hydratase, mitochondrial</fullName>
            <ecNumber evidence="2">4.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_12868</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717318.1">
        <property type="nucleotide sequence ID" value="XM_003717270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8F1"/>
    <dbReference type="SMR" id="G4N8F1"/>
    <dbReference type="STRING" id="242507.G4N8F1"/>
    <dbReference type="GeneID" id="5050236"/>
    <dbReference type="KEGG" id="mgr:MGG_12868"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12868"/>
    <dbReference type="eggNOG" id="KOG1680">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="InParanoid" id="G4N8F1"/>
    <dbReference type="OMA" id="FCDARED"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000019">
        <property type="entry name" value="Enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA50999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="291" mass="31377" checksum="7A19A8EFFE857FFD" modified="2011-12-14" version="1">MNAFRALRPVASKIQAPTLPRITRGFAASSRLGYEHIQVSEPRPGVGQVTLNRPKALNALSTPLIKELNTALGDYQKSDSISVIVITGSQKAFAAGADIKEMAPLTFSKAYTESFIENWSDLTTQVKKPIIAAVSGHALGGGCELALMCDFIYCTESANFGQPEIKLGVIPGAGGSQRLTKAVGKARAMELILTGKSMTGAEAARWGVAARSFATYEELMEATLKTAETIASYSKVAVQACKEVVNKSQDLGLRDGVEYERRVFHSLFGSQDQKIGMTAFAEKKKPEWTHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8N5</accession>
    <name>G4N8N5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716548.1">
        <property type="nucleotide sequence ID" value="XM_003716500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8N5"/>
    <dbReference type="SMR" id="G4N8N5"/>
    <dbReference type="STRING" id="242507.G4N8N5"/>
    <dbReference type="GeneID" id="2676547"/>
    <dbReference type="KEGG" id="mgr:MGG_03394"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03394"/>
    <dbReference type="eggNOG" id="ENOG502S9U6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028281_6_0_1"/>
    <dbReference type="InParanoid" id="G4N8N5"/>
    <dbReference type="OMA" id="LARIFHM"/>
    <dbReference type="OrthoDB" id="438641at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465932" description="SET domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="47352" checksum="12ACB4C29F93FBD0" modified="2011-12-14" version="1">MAQGRKRTHQIPPVWFLSLLPAALGLPRLTSECPAGFKGRLDSPGYTQCAVPTDDASGPHPSQWAPWTHKPLCVEGAAPKTQPSGGSDDGPSGTTAPPPRTKFCVYTNAHAGDGGMSIITTPEHAASSLHLLEDPSLHLPSSRSSSSSSRLHNASTTPAYKVVDVPGKGKGVLATRRIRRFEPFMLERAALATDNLFASLVERHAGYRLLREAVGRLADPDRVLSLARSSPHAGDAVENVLRTNSFAGELDGAPHMVLFPLIARMNHACKPKYPRTTKTFSYSPDAALGMEFQQRQTQLQNTWGFKCTCAACTAPESSRAVSDQRRRDIKAKRQELVDSIDNADAPVAVRLSLEILDLLASEHLPSLFAEQYEILARIFHMIRYKDKAIKYAEMALKVLDIYGALDEDDEHKGIEALMASFDEPSLPAMGERPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA08</accession>
    <name>G4NA08_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717573.1">
        <property type="nucleotide sequence ID" value="XM_003717525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA08"/>
    <dbReference type="GeneID" id="2680719"/>
    <dbReference type="KEGG" id="mgr:MGG_09772"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09772"/>
    <dbReference type="eggNOG" id="ENOG502SK0A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072119_0_0_1"/>
    <dbReference type="InParanoid" id="G4NA08"/>
    <dbReference type="OMA" id="HLPRIKT"/>
    <dbReference type="OrthoDB" id="2906425at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF51">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="68"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="416" mass="45952" checksum="0EB4CAFCBB41D475" modified="2011-12-14" version="1">MAEPKAHLPPVLSDATIRSLSIALGLPEPVTISRLSATAEYHGIYLLRFDADSTGRITPPLQKQAVDADGSATLVLRVSGRHLPGLKTRNEVGCMAWVRSNTTIPVPAVIRYDDTQDNALGHEFTLLEKAPGVSVDTVYDTLGDAQKRLLVEQLTGYIMQLHDKRWREPCVGGLVPASGDGADPVPASGGGAEPVPGPVVEETFWQQPDVDKFWPLGETVDTLNPTQGPFPGYAAYIAAIIERYIHAIERHESLMAFRDLVPRLKAFIAAIRDPERTGGLNNAAYVVAHKDMHFANIMCDPTQPDKMPITAVLDWEFSGIVPANRWNPTRAFLWNGQQNDVSKQEKERLFEWFKEQLKQRAPHILDDMEPSKAQETMQTVQSFLRAIVEVCPRGQCADKVGSWRTTVEASLEAFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA73</accession>
    <name>G4NA73_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715942.1">
        <property type="nucleotide sequence ID" value="XM_003715894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA73"/>
    <dbReference type="GeneID" id="2678764"/>
    <dbReference type="KEGG" id="mgr:MGG_08442"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08442"/>
    <dbReference type="HOGENOM" id="CLU_1540366_0_0_1"/>
    <dbReference type="InParanoid" id="G4NA73"/>
    <dbReference type="OMA" id="CRPFKVI"/>
    <dbReference type="OrthoDB" id="10416126at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466245" evidence="2">
        <location>
            <begin position="20"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="174" mass="18189" checksum="B530C94989D61019" modified="2011-12-14" version="1">MQRLSIFKLLVLGVSAAEARPLAVTTGSVGTPDGRTAEVDALPLGKAEQLTHPLLRMGPGPAISTEARAVQLPDDATRDRTSQPFRLIRGPGPTTAKGPYPVGVQTDPSCRPFKVIRGPGPTTAKGPYTLGMPTTAEHMPKEKPNVAASTIPTDDVNKAASSGTIFDKIGVNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAR1</accession>
    <name>G4NAR1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716822.1">
        <property type="nucleotide sequence ID" value="XM_003716774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAR1"/>
    <dbReference type="SMR" id="G4NAR1"/>
    <dbReference type="STRING" id="242507.G4NAR1"/>
    <dbReference type="GeneID" id="2676966"/>
    <dbReference type="KEGG" id="mgr:MGG_03168"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03168"/>
    <dbReference type="eggNOG" id="ENOG502RES8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1652512_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAR1"/>
    <dbReference type="OMA" id="QKPDANW"/>
    <dbReference type="OrthoDB" id="5208004at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="136" mass="14852" checksum="98A7926FA7730DF5" modified="2011-12-14" version="1">MPPKKKVPAVSDVSRKPATENDLRFFESYLRNMKTQPDVAWDDVAADMGLAHGGSARERFRQIKQKLGWGVGPATPKRKKKATAVIEADDSDDVQIAEPTPKKQKSTKTTAAGSKKDNVKTEETEGAVDQDWGGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAX8</accession>
    <name>G4NAX8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_00685</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the heterotrimeric canonical replication protein A complex (RPA).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718324.1">
        <property type="nucleotide sequence ID" value="XM_003718276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAX8"/>
    <dbReference type="SMR" id="G4NAX8"/>
    <dbReference type="FunCoup" id="G4NAX8">
        <property type="interactions" value="1135"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAX8"/>
    <dbReference type="GeneID" id="2675023"/>
    <dbReference type="KEGG" id="mgr:MGG_00685"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00685"/>
    <dbReference type="eggNOG" id="KOG0851">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012393_2_0_1"/>
    <dbReference type="InParanoid" id="G4NAX8"/>
    <dbReference type="OMA" id="DQCDAFY"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000041">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000064">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000090">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000117">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004591">
        <property type="entry name" value="Rfa1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00617">
        <property type="entry name" value="rpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Replication factor-A protein 1 N-terminal" evidence="11">
        <location>
            <begin position="9"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="OB" evidence="10">
        <location>
            <begin position="192"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A OB" evidence="13">
        <location>
            <begin position="301"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="12">
        <location>
            <begin position="456"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA48740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="610" mass="67929" checksum="F830BB711EB96084" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB65</accession>
    <name>G4NB65_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718411.1">
        <property type="nucleotide sequence ID" value="XM_003718363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB65"/>
    <dbReference type="GeneID" id="12984084"/>
    <dbReference type="KEGG" id="mgr:MGG_17410"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17410"/>
    <dbReference type="HOGENOM" id="CLU_1090183_0_0_1"/>
    <dbReference type="InParanoid" id="G4NB65"/>
    <dbReference type="OrthoDB" id="10533845at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="255" mass="28076" checksum="926D51247FAFB8CE" modified="2011-12-14" version="1">MLLFLVWCSLFLGDERVRVHIRQGRGAKDEQRGGGVGWCGLGTFVHLESFIAGSLELARPVAGQPGRSLVHHQVSCQTRVPAQVCAKWDVNLPLPAVLLWTRHPERAYWQPNQGKLDGGRSSFCHLSSSRVKDQTSRGKLHRSMAANFCGTFVCAAAGTALMRTAHVALYFGELFTILFPVGFSSFSLDVVFNVPTPTFQCNLPNVIISTFFLSVPPIHEDCIDTRDWVRQTIGVWFCLGNAFTKGARTAAVPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBJ4</accession>
    <name>G4NBJ4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PD-(D/E)XK nuclease-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10917</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717683.1">
        <property type="nucleotide sequence ID" value="XM_003717635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBJ4"/>
    <dbReference type="GeneID" id="2677063"/>
    <dbReference type="KEGG" id="mgr:MGG_10917"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10917"/>
    <dbReference type="HOGENOM" id="CLU_027219_5_1_1"/>
    <dbReference type="InParanoid" id="G4NBJ4"/>
    <dbReference type="OMA" id="YENIMDI"/>
    <dbReference type="OrthoDB" id="5244165at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046797">
        <property type="entry name" value="PDDEXK_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20516">
        <property type="entry name" value="PDDEXK_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PD-(D/E)XK nuclease-like" evidence="2">
        <location>
            <begin position="166"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="424" mass="47682" checksum="0A0AE367AC0028AD" modified="2011-12-14" version="1">MQRQPSLPDLHFSSLHDKIDAWLDGTGLDTEYNSSPNIKKRAFDPDMPTPTGTSRSGSPSKRQRTDGAASLSNQSLQSAQSSSFPPTSQSIASISRRPRSPKKTADKLFGKVFNANASLDNQPETPLPPDMLNLYENIMDIHDNTIPIYPLGAKNQIQTLIRNTSDDRFIPDPDFEQHEDKKKLDAAIELDDLLAIQKTAERCARYLSHEGTWNSDVHARILRRAAAPYSGITAVGATTAGIQPEWRSGTTADDASNGSKMVDYLLIIDDSDIALGHAIRNHTRMVNQTSVDDFLEQPIGISIETKVSQTWSNQGKLQLGNWSASLLYRWSLLPTLCTDSCRKPDDYVAPPVIKALPIVLVTGHFWEVYFFCDEEDNYQMYGPVDLGNTRSLKEIYKLLASLRVLIRWVDVQLRDWFYRLFHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBM5</accession>
    <name>G4NBM5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717714.1">
        <property type="nucleotide sequence ID" value="XM_003717666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBM5"/>
    <dbReference type="GeneID" id="5048806"/>
    <dbReference type="KEGG" id="mgr:MGG_14248"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14248"/>
    <dbReference type="HOGENOM" id="CLU_1768473_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBM5"/>
    <dbReference type="OMA" id="INTPFVC"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="147" mass="16045" checksum="160E34E6C804E7A5" modified="2011-12-14" version="1">MKQSAALHLEKVCGQADRVVSRRTSRESWTSPESSLHGADSSATIFRVQLGRFIKGFINRSEFGFADAPFKSGMSPGMYPALPAQGIPNAGSARGPTESFLIQLIRKLTGNGKLSGHQNIVQKPINTPFVCRFPALWCRDRAASRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC21</accession>
    <name>G4NC21_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bud22 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_00457</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718608.1">
        <property type="nucleotide sequence ID" value="XM_003718560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC21"/>
    <dbReference type="STRING" id="242507.G4NC21"/>
    <dbReference type="GeneID" id="2674881"/>
    <dbReference type="KEGG" id="mgr:MGG_00457"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00457"/>
    <dbReference type="eggNOG" id="ENOG502S6Z4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029647_0_0_1"/>
    <dbReference type="InParanoid" id="G4NC21"/>
    <dbReference type="OMA" id="ALWEKKF"/>
    <dbReference type="OrthoDB" id="3364872at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037393">
        <property type="entry name" value="Bud22/SRFB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015158">
        <property type="entry name" value="Bud22_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23325">
        <property type="entry name" value="SERUM RESPONSE FACTOR-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23325:SF1">
        <property type="entry name" value="SERUM RESPONSE FACTOR-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09073">
        <property type="entry name" value="BUD22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bud22" evidence="3">
        <location>
            <begin position="17"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="441" mass="48512" checksum="8B67F831EBCF3436" modified="2011-12-14" version="1">MPKRKRAEEEGFDKSFERFNKELFRALKVAKGFERQRLAKRVKDVKLPQDKIQRLEQEVEVLKALDLHQAAQAHLCSALLKVKAAAQSPLLPEAIKNGVPKPEISDEERHALHNVTSALYKRNQVRAVVSAAIPALCQSLGVSPPGDKSKAKGESNSSKKDFKGDAKPKEETRKRRAAQSSEEQEDSSSDEDGYESGEEELDDETIDRMEAMLGGSSSEEEIASDDEGLARLKQLAQRSSFDDDISLPGSGSALEEEYPEDDEVTIPSSSSSESDAAPPPPKKAKNEKKAKPIKDDEIVESVALPTLMGGYISGSEEASDVDVAPAPRKNRRGQKARQALAEKKYGDKAKHLGKQKEAGWDSKRGAVDAGDGKPWKRGVRNPLQQKKDGEGSRGPKQEETKKPEKKTRDDDGPLHPSWLAKKKAKQAQENASFQGKKITFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCG0</accession>
    <name>G4NCG0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sad1 interacting factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_01093</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717841.1">
        <property type="nucleotide sequence ID" value="XM_003717793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCG0"/>
    <dbReference type="STRING" id="242507.G4NCG0"/>
    <dbReference type="GeneID" id="2674729"/>
    <dbReference type="KEGG" id="mgr:MGG_01093"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01093"/>
    <dbReference type="eggNOG" id="ENOG502S1RY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_819228_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCG0"/>
    <dbReference type="OMA" id="MRYGQIF"/>
    <dbReference type="OrthoDB" id="5393181at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028143">
        <property type="entry name" value="Get2/sif1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28263">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28263:SF1">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08690">
        <property type="entry name" value="GET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA48257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="36067" checksum="A1F5E7709F18B8E4" modified="2011-12-14" version="1">MTESADADAAAARASEQARLRKERREAKIKAGGSARLNRITGLGGGFQRDPIPTATASGTDAATTTASPTPAAAPTPDHADPDEVDISSQHFPSPRRQQQQQQQPPSEMSEAQLRQLMLGMDMPRGDGSAPANPFAGNPFLNPGLGGPGGQPGGPEDPMMKMLQQMMGGQMPGGGAGGFPGMPGAAPQQQQQQQAPLDTYSAAWRILHLVVALGLGLYIALTGAFMGTLEARDAARLASDAGMSSADLDESNNNRARFFYMFATAEAVLLTSRFFLDRSRAPPPGILWTVAGFLPPSMKRYLETALRYGQVFTTVRSDLLVCVFVLGVCHWWRTIGVVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCK4</accession>
    <name>G4NCK4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vacuolar morphogenesis protein AvaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_01054</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VAM6/VPS39 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717885.1">
        <property type="nucleotide sequence ID" value="XM_003717837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCK4"/>
    <dbReference type="SMR" id="G4NCK4"/>
    <dbReference type="STRING" id="242507.G4NCK4"/>
    <dbReference type="GeneID" id="2674839"/>
    <dbReference type="KEGG" id="mgr:MGG_01054"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01054"/>
    <dbReference type="eggNOG" id="KOG2063">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004190_1_1_1"/>
    <dbReference type="InParanoid" id="G4NCK4"/>
    <dbReference type="OMA" id="EEYCNQV"/>
    <dbReference type="OrthoDB" id="10260443at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019452">
        <property type="entry name" value="VPS39/TGF_beta_rcpt-assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019453">
        <property type="entry name" value="VPS39/TGFA1_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF49">
        <property type="entry name" value="VAM6_VPS39-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10366">
        <property type="entry name" value="Vps39_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10367">
        <property type="entry name" value="zf-Vps39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CNH" evidence="5">
        <location>
            <begin position="18"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="425"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="559"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1026"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="448"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="513"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA48301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1049" mass="115963" checksum="C38F041BDD524243" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND12</accession>
    <name>G4ND12_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peptide transporter MTD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_00304</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718786.1">
        <property type="nucleotide sequence ID" value="XM_003718738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND12"/>
    <dbReference type="GeneID" id="5050764"/>
    <dbReference type="KEGG" id="mgr:MGG_00304"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00304"/>
    <dbReference type="eggNOG" id="KOG2262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004965_3_0_1"/>
    <dbReference type="InParanoid" id="G4ND12"/>
    <dbReference type="OMA" id="HVLIFYG"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="522"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="673"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="722"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="758"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA49202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="809" mass="88387" checksum="F5435AEFD9DA2E54" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE24</accession>
    <name>G4NE24_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MGMT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718143.1">
        <property type="nucleotide sequence ID" value="XM_003718095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE24"/>
    <dbReference type="SMR" id="G4NE24"/>
    <dbReference type="GeneID" id="2674670"/>
    <dbReference type="KEGG" id="mgr:MGG_00838"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00838"/>
    <dbReference type="eggNOG" id="KOG4062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_52_5_1"/>
    <dbReference type="InParanoid" id="G4NE24"/>
    <dbReference type="OMA" id="DEAEWWF"/>
    <dbReference type="OrthoDB" id="2548197at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052520">
        <property type="entry name" value="ATL_DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42942">
        <property type="entry name" value="6-O-METHYLGUANINE DNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42942:SF1">
        <property type="entry name" value="ALKYLTRANSFERASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="Methylated DNA-protein cysteine methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding" evidence="2">
        <location>
            <begin position="10"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="127" mass="13900" checksum="E4DC82C959345DDC" modified="2011-12-14" version="1">MPQSEEAAAFFYAVYSAVQEIPPGKVTTYGHIAHLVGQPQRPRQVGVCLKHLSEDDNAVHNHNNVPWQRVINAKGIISPRSAPSGSQNQATALRAEGVTVTTGALGELMVDFKEYGWFPEMLPSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE86</accession>
    <name>G4NE86_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">von Willebrand RING finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_00134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718999.1">
        <property type="nucleotide sequence ID" value="XM_003718951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE86"/>
    <dbReference type="SMR" id="G4NE86"/>
    <dbReference type="STRING" id="242507.G4NE86"/>
    <dbReference type="GeneID" id="2675193"/>
    <dbReference type="KEGG" id="mgr:MGG_00134"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00134"/>
    <dbReference type="eggNOG" id="ENOG502QTWJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006368_0_0_1"/>
    <dbReference type="InParanoid" id="G4NE86"/>
    <dbReference type="OMA" id="SEAHWAQ"/>
    <dbReference type="OrthoDB" id="299997at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01466">
        <property type="entry name" value="vWA_C3HC4_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000014">
        <property type="entry name" value="von Willebrand and RING finger domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF43">
        <property type="entry name" value="ZINC FINGER (C3HC4-TYPE RING FINGER) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="116"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="620"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="552"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="994"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="272"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="585"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA49415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1161" mass="127946" checksum="1D555A1E07B97D90" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2021-06-02" modified="2025-02-05" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF50</accession>
    <name>GAS2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Appressoria-specific virulence factor GAS2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GAS2</name>
        <name evidence="1" type="synonym">MAS1</name>
        <name type="ORF">MGG_04202</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2002" name="Plant Cell" volume="14" first="2107" last="2119">
            <title>Two novel fungal virulence genes specifically expressed in appressoria of the rice blast fungus.</title>
            <authorList>
                <person name="Xue C."/>
                <person name="Park G."/>
                <person name="Choi W."/>
                <person name="Zheng L."/>
                <person name="Dean R.A."/>
                <person name="Xu J.R."/>
            </authorList>
            <dbReference type="PubMed" id="12215509"/>
            <dbReference type="DOI" id="10.1105/tpc.003426"/>
        </citation>
        <scope>INDUCTION</scope>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <scope>SUBCELLULAR LOCATION</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2013" name="Gene Expr. Patterns" volume="13" first="133" last="141">
            <title>Complexity of roles and regulation of the PMK1-MAPK pathway in mycelium development, conidiation and appressorium formation in Magnaporthe oryzae.</title>
            <authorList>
                <person name="Jin Q."/>
                <person name="Li C."/>
                <person name="Li Y."/>
                <person name="Shang J."/>
                <person name="Li D."/>
                <person name="Chen B."/>
                <person name="Dong H."/>
            </authorList>
            <dbReference type="PubMed" id="23454094"/>
            <dbReference type="DOI" id="10.1016/j.gep.2013.02.003"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="5 6">Appressoria-specific virulence factor required for appressorial penetration in host and lesion development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Exclusively located in the cytoplasm of appressoria cells.</text>
    </comment>
    <comment type="induction">
        <text evidence="5">Expressed specifically during appressorium formation.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="5 6">Does not affect vegetative growth, conidiation, or appressoria formation, but redices in appressorial penetration and lesion development.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719620.1">
        <property type="nucleotide sequence ID" value="XM_003719572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF50"/>
    <dbReference type="GlyCosmos" id="G4NF50">
        <property type="glycosylation" value="1 site, No reported glycans"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_04202T0">
        <property type="protein sequence ID" value="MGG_04202T0"/>
        <property type="gene ID" value="MGG_04202"/>
    </dbReference>
    <dbReference type="GeneID" id="2677126"/>
    <dbReference type="KEGG" id="mgr:MGG_04202"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04202"/>
    <dbReference type="eggNOG" id="ENOG502SM0P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047729_4_0_1"/>
    <dbReference type="InParanoid" id="G4NF50"/>
    <dbReference type="OMA" id="TMTFHQV"/>
    <dbReference type="OrthoDB" id="5310497at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF1">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466884" description="Appressoria-specific virulence factor GAS2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q9P470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="12215509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="6">
        <source>
            <dbReference type="PubMed" id="23454094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="7">
        <source>
            <dbReference type="PubMed" id="12215509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="290" mass="29414" checksum="4FFA475763520260" modified="2011-12-14" version="1" precursor="true">MKYTSAILISAFAATNVFAHGVVTEVQGANGVTLPGLTAIDGTPRDCPNPGCGSEADTAIIRDRELGTSRASALGRTQGGGPVDAAKMIELFMDGASVNKSDVVAARERHAANLARRATLLPRAGGGTSTPKGTEETGVKAATGIAATKGLPTTNDDGTINIVFHQVNQDGAGPLTADIDSTSGGQDVSAFQKAKITTNVPGLGIAGLSAAQTMDFPVAVQMPAGATCSGSVGGANNVCIARLRNAAVTGPFGGSVAFTQSPAARKRAIEYNLAKRRFARSLATDEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFX2</accession>
    <name>G4NFX2_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15374</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719296.1">
        <property type="nucleotide sequence ID" value="XM_003719248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFX2"/>
    <dbReference type="GeneID" id="12985747"/>
    <dbReference type="KEGG" id="mgr:MGG_15374"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15374"/>
    <dbReference type="HOGENOM" id="CLU_1768475_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFX2"/>
    <dbReference type="OrthoDB" id="10356860at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466489" evidence="1">
        <location>
            <begin position="23"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="147" mass="16728" checksum="FACD6F2C03449351" modified="2011-12-14" version="1">MRASIITLTVLSLVLHVAASAAKPPVLPDLLYFGTQRDMKTIHSDGGLLPGDVLAGHARYLYLMFRDEPEFKLSTVLAARDGHTYTVMTRNWTSSFKPLDDEGRSWEATEKIPFLAVVGREEFRKGHIPIYYDIFDWQWDQNENKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGE3</accession>
    <name>G4NGE3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719467.1">
        <property type="nucleotide sequence ID" value="XM_003719419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGE3"/>
    <dbReference type="GeneID" id="12985919"/>
    <dbReference type="KEGG" id="mgr:MGG_17631"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17631"/>
    <dbReference type="HOGENOM" id="CLU_2850172_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGE3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="65" mass="6971" checksum="6AB1CDFEBF0BD9AB" modified="2011-12-14" version="1">MNMPTSLQPGSEDADQTSPESKFATQSDGILYSRPLDGLPESVSYSAERHVCAPSLIGTFCSQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGJ3</accession>
    <name>G4NGJ3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719517.1">
        <property type="nucleotide sequence ID" value="XM_003719469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGJ3"/>
    <dbReference type="SMR" id="G4NGJ3"/>
    <dbReference type="GeneID" id="12985982"/>
    <dbReference type="KEGG" id="mgr:MGG_17641"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17641"/>
    <dbReference type="HOGENOM" id="CLU_2038530_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGJ3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="121" mass="14585" checksum="308C02FA7B535114" modified="2011-12-14" version="1">MNNLISSEGCSHKYCWQLEDEVEHERMHRLLIDQCEQLQNTIFDKELIKQELCLTKDALIKTTSQLRLTNENLQNLRTAARTEARSKHQLILTLWNRLNETQQIENKRISRKRKYDDFLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH12</accession>
    <name>G4NH12_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucan synthesis regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KNR4/SMI1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719889.1">
        <property type="nucleotide sequence ID" value="XM_003719841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH12"/>
    <dbReference type="SMR" id="G4NH12"/>
    <dbReference type="STRING" id="242507.G4NH12"/>
    <dbReference type="GeneID" id="2677425"/>
    <dbReference type="KEGG" id="mgr:MGG_03970"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03970"/>
    <dbReference type="eggNOG" id="ENOG502QTAZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024700_0_0_1"/>
    <dbReference type="InParanoid" id="G4NH12"/>
    <dbReference type="OMA" id="ESLMVHD"/>
    <dbReference type="OrthoDB" id="2305498at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070880">
        <property type="term" value="P:fungal-type cell wall beta-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009203">
        <property type="entry name" value="Knr4/Smi1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051873">
        <property type="entry name" value="KNR4/SMI1_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432:SF1">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017023">
        <property type="entry name" value="KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Knr4/Smi1-like" evidence="3">
        <location>
            <begin position="162"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="516"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="518"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="532"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="571" mass="62198" checksum="C2AD2008D1895F3B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHJ1</accession>
    <name>G4NHJ1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720068.1">
        <property type="nucleotide sequence ID" value="XM_003720020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHJ1"/>
    <dbReference type="SMR" id="G4NHJ1"/>
    <dbReference type="GeneID" id="12987144"/>
    <dbReference type="KEGG" id="mgr:MGG_17745"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17745"/>
    <dbReference type="HOGENOM" id="CLU_2740536_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHJ1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="71" mass="8221" checksum="7437343A33872F14" modified="2011-12-14" version="1">MASKKWLKLWTESEGEANTTLLHTWNLLHHHEPERRAVPVPLEMKCFKHATTGNVEQACYQHGAVGRQCQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHN0</accession>
    <name>G4NHN0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_03785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720107.1">
        <property type="nucleotide sequence ID" value="XM_003720059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHN0"/>
    <dbReference type="GeneID" id="2677497"/>
    <dbReference type="KEGG" id="mgr:MGG_03785"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03785"/>
    <dbReference type="eggNOG" id="ENOG502SHDQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1142778_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHN0"/>
    <dbReference type="OMA" id="NIFEYRG"/>
    <dbReference type="OrthoDB" id="5240961at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="243" mass="26941" checksum="8837C9F550FA27AF" modified="2011-12-14" version="1">MTPQIQYTVQYSARLCTGGSEGGLRHSEPPFFLRSSAALAACPAIASHSGSREAANQRLLSLFCVPQPGESDTEEERFGLSTNYAVFFRLRDEEKSRAINLCVGDLVLVVQAHHYALDAIEYSNYIMQLAANYVDHLLAMVAPIRDKRTISLRLDSYPPMSMLMTDHRPADVGSFDFGFGKPITYRHLFGGFSTAGAVVMYAPVRSADPDEGCVFTVTMEKELVGKMRAMPEFSNIFEYRGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJJ7</accession>
    <name>G4NJJ7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721150.1">
        <property type="nucleotide sequence ID" value="XM_003721102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJJ7"/>
    <dbReference type="GeneID" id="2682853"/>
    <dbReference type="KEGG" id="mgr:MGG_02637"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02637"/>
    <dbReference type="HOGENOM" id="CLU_1454709_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJJ7"/>
    <dbReference type="OrthoDB" id="5221719at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="186" mass="20411" checksum="D45B3E20A671E418" modified="2011-12-14" version="1">MYIPDHQEQQQQQQQPEQTMSEEMVQAMLRSFMYSAIVAGSVAVIAALAYCAVQLTSRDRNGVTTARGRYGDTRYIYSMTAPPIPYVMSEAAAQSGRPHHDIHTPTHGTSQFSMKELYDIMRTNIFSSDSDEANARGQDDIVNQHSSLLANADVGQRNSSLDGFGTTAESENVAPAPSDGADRYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKE2</accession>
    <name>G4NKE2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secretory phospholipase A2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_09019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721321.1">
        <property type="nucleotide sequence ID" value="XM_003721273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKE2"/>
    <dbReference type="SMR" id="G4NKE2"/>
    <dbReference type="GeneID" id="2680066"/>
    <dbReference type="KEGG" id="mgr:MGG_09019"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09019"/>
    <dbReference type="eggNOG" id="ENOG502S8PP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053014_3_0_1"/>
    <dbReference type="InParanoid" id="G4NKE2"/>
    <dbReference type="OMA" id="RNYKAQG"/>
    <dbReference type="OrthoDB" id="5120271at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050482">
        <property type="term" value="P:arachidonate secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.90.10">
        <property type="entry name" value="Phospholipase A2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036444">
        <property type="entry name" value="PLipase_A2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015141">
        <property type="entry name" value="PLipase_A2_prok/fun"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09056">
        <property type="entry name" value="Phospholip_A2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48619">
        <property type="entry name" value="Phospholipase A2, PLA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21334" checksum="B393D7E024E30B84" modified="2011-12-14" version="1">MNFLILLLATLVAATPMPKKLAKAEPKGAGLKASAADPKLIPVTDELVFKVPLETFIARRNKLDPAALDFSSDNCTKAPNNPLGFPFTPGCNRHDFGYQNFQAQGRFTAENKKKIDDNFQQDLKHQCSSVKTAAKPACNGLADVYHAAVRKFGGRKELQAKRDDSLEAEFQEKLAIYKVLEAEYMRMKARSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKV1</accession>
    <name>G4NKV1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">RNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_03017</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720672.1">
        <property type="nucleotide sequence ID" value="XM_003720624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKV1"/>
    <dbReference type="STRING" id="242507.G4NKV1"/>
    <dbReference type="GeneID" id="2682570"/>
    <dbReference type="KEGG" id="mgr:MGG_03017"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03017"/>
    <dbReference type="eggNOG" id="KOG0154">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012131_2_0_1"/>
    <dbReference type="InParanoid" id="G4NKV1"/>
    <dbReference type="OMA" id="MYDDRSP"/>
    <dbReference type="OrthoDB" id="29221at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055494">
        <property type="entry name" value="DUF7066"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948:SF3">
        <property type="entry name" value="FI21118P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23217">
        <property type="entry name" value="DUF7066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="112"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="13">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="G-patch" evidence="12">
        <location>
            <begin position="713"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="425"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="662"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="11"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="665"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="697"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA45929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="795" mass="89488" checksum="C958A98A0DFD543F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL21</accession>
    <name>G4NL21_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720697.1">
        <property type="nucleotide sequence ID" value="XM_003720649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL21"/>
    <dbReference type="GeneID" id="12984763"/>
    <dbReference type="KEGG" id="mgr:MGG_17894"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17894"/>
    <dbReference type="HOGENOM" id="CLU_1686987_0_0_1"/>
    <dbReference type="InParanoid" id="G4NL21"/>
    <dbReference type="OrthoDB" id="10407568at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466434" evidence="1">
        <location>
            <begin position="19"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA45954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="156" mass="16154" checksum="776D82F6872CAD9A" modified="2011-12-14" version="1">MQFPSALIFGLLLQSALAEPKQNTGRPGECPPGQIPRVNGECPTGSFGASGGTCPAGTVPPTDGICPDGHQPCNLEGGHLSKRYEGMDQSLVRRDGGIIATVGCLVVSTLCCLLCCCGRPRGGHSNDGSHGRSYRAGYRSGYTDGCFTSEIASDCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLA1</accession>
    <name>G4NLA1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipase 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_14057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721489.1">
        <property type="nucleotide sequence ID" value="XM_003721441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLA1"/>
    <dbReference type="SMR" id="G4NLA1"/>
    <dbReference type="GeneID" id="5051416"/>
    <dbReference type="KEGG" id="mgr:MGG_14057"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14057"/>
    <dbReference type="eggNOG" id="ENOG502QRF9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029538_5_2_1"/>
    <dbReference type="InParanoid" id="G4NLA1"/>
    <dbReference type="OrthoDB" id="2373480at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF5">
        <property type="entry name" value="LIP-DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03583">
        <property type="entry name" value="LIP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029171">
        <property type="entry name" value="Esterase_LipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013434266" evidence="2">
        <location>
            <begin position="21"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR029171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="380" mass="41196" checksum="5C3FABEA587D6C1F" modified="2011-12-14" version="1">MGRFANVWMPIYGLLTTVLATELIPPSQDPWYAAPPGFESKAPGTILRTRQAPPNITALANNSVEAHQLLFRSTDTLYRPSWAVTTVFLPTEESRAGRNKPALLSYQIPYNTLDVDQSPSYGLSTIYGENIMADVRQGLSQGWIVSVPDFEGPEAAFSAGPQAGHAVLDSVRAVLSFTNLTEPDSARYALWGYSGGAFASGFAGELQASYAPELDIAGIAIGEARQYLVDHLHKEGTHNATSFLSALHIPAAEAIALFSGQDIFGYFTNGDEIMRAPELARVFGNNWHESYHGIPQMPVYAYKAIHDENTNIRTTDEHVARICGVGANVLYDRNTVGGHEDEAISGGRRALKWLSDALDGRQLEPANGCKVQNVTVGVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G5EGV6</accession>
    <name>G5EGV6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGCH7_ch7g8</name>
        <name evidence="11" type="ORF">MGG_15393</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15</strain>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721509.1">
        <property type="nucleotide sequence ID" value="XM_003721461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EGV6"/>
    <dbReference type="GeneID" id="12986101"/>
    <dbReference type="KEGG" id="mgr:MGG_15393"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15393"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_809092_0_0_1"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="PHI-base" id="PHI:4490"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EAQ70601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA46766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="343" mass="38941" checksum="0461CF269BAB442F" modified="2011-12-14" version="1">MGIPRRMGQRRPNRCWGPRGRARAEKKSKRSTGDREQYAGFVEHFPSTEYVCCPAVGCFIYILHADCLSSWSHFKPVAESILGLHFYRGRTDSSHQGRDLWDQLASRIGALNGDKRHVKYTAGLRKSHWNKGPQSLLLFLSAIFRAFPTMGSTCWECGKYFPSGPVALGQHCQSTSHTECRRCYETFNNAQDRIDHEADQHAYCEDCDREFQSPNNARQHLNSRTHRGYSIQCPLCGKAYTTATGIVYHLESGSCPNAQNLSRDEVFRLVRSRDPQGVISKKLIGWTGDVEYEATHHTWNGYGYECYLCHRVFHQIHSLSQHLNSPALGGNENGTDRRGSCGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHD6</accession>
    <name>G5EHD6_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g229</name>
        <name evidence="3" type="ORF">MGG_09055</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721292.1">
        <property type="nucleotide sequence ID" value="XM_003721244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHD6"/>
    <dbReference type="SMR" id="G5EHD6"/>
    <dbReference type="STRING" id="242507.G5EHD6"/>
    <dbReference type="GeneID" id="5050551"/>
    <dbReference type="KEGG" id="mgr:MGG_09055"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09055"/>
    <dbReference type="HOGENOM" id="CLU_1332157_0_0_1"/>
    <dbReference type="OrthoDB" id="5235934at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834252" evidence="1">
        <location>
            <begin position="24"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="206" mass="21100" checksum="587EB768BF2FBA9B" modified="2011-12-14" version="1">MQFTNSFLTTLTTALVLASGAQAAMSIDQIVGGLNMFRDMAKQLQPAASALSPNPLAILTNSNTANMQQCADGFAQAAQLGGGFVNGITGTAAVDGEYADQQRDDIAAAYGDCAQSHLLLLKTVANAQSGVGYGTAQGKSLINSMGGIQSVISGLTANLVEIVGANSDAASQLNANKNKLISGATRVKACYSADLITCNMLRLQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHM9</accession>
    <name>G5EHM9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGCH7_ch7g772</name>
        <name evidence="5" type="ORF">MGG_02990</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15</strain>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720702.1">
        <property type="nucleotide sequence ID" value="XM_003720654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHM9"/>
    <dbReference type="SMR" id="G5EHM9"/>
    <dbReference type="GeneID" id="2682543"/>
    <dbReference type="KEGG" id="mgr:MGG_02990"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02990"/>
    <dbReference type="HOGENOM" id="CLU_1835547_0_0_1"/>
    <dbReference type="OrthoDB" id="10404621at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834273" evidence="3">
        <location>
            <begin position="20"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EAQ71365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA45959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="140" mass="15763" checksum="8FF9C6B9CC975D6B" modified="2011-12-14" version="1">MRFQTATLAILATAHTGSGATTDSQQHITECQNNIASYQRQITECQNRITNYQNQITEFQKQIDHPEPQERENWGACMTKCMIKWGKRIPGKKSDAGCLVFCDSQCMKLQNYLPSEDRVRGDQTDNNGKAAGGEHAFEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHR0</accession>
    <name>G5EHR0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGCH7_ch7g754</name>
        <name evidence="4" type="ORF">MGG_02976</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15</strain>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
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        <property type="protein sequence ID" value="EAQ71347.1"/>
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        <property type="component" value="Chromosome 7"/>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
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        <property type="entry name" value="HET"/>
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    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
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    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
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    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="FxSxx_TPR"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="26"/>
            <end position="116"/>
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    </feature>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="281"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF06985"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EAQ71347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA45981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1042" mass="118735" checksum="9F64C10DF5237232" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI30</accession>
    <name>G5EI30_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g1114</name>
        <name evidence="3" type="ORF">MGG_10335</name>
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    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="EHA45739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720482.1">
        <property type="nucleotide sequence ID" value="XM_003720434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI30"/>
    <dbReference type="GeneID" id="2681910"/>
    <dbReference type="KEGG" id="mgr:MGG_10335"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10335"/>
    <dbReference type="HOGENOM" id="CLU_2121574_0_0_1"/>
    <dbReference type="OrthoDB" id="10300250at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834289" evidence="1">
        <location>
            <begin position="22"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="114" mass="12492" checksum="E254FD705A9B3514" modified="2011-12-14" version="1">MQVGQLVFVAIGLSLLHVVIAATDLTETDTIAGADTRLVPGCLVKLYRPPKYIGCFDRSILVGAKCIPVQTTWKIKGHDISVWNGCSTVKGINLPKGWFVKGESAQCKVWHRKQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-09-11" modified="2025-02-05" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>A4RCW0</accession>
    <accession>G4NKF7</accession>
    <accession>Q2KH17</accession>
    <name>CSM3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Chromosome segregation in meiosis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">CSM3</name>
        <name type="ORF">MGCH7_ch7g168</name>
        <name type="ORF">MGG_09005</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T.K."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Forms a fork protection complex (FPC) with TOF1 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSM3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003721288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RCW0"/>
    <dbReference type="SMR" id="A4RCW0"/>
    <dbReference type="STRING" id="242507.A4RCW0"/>
    <dbReference type="EnsemblFungi" id="MGG_09005T0">
        <property type="protein sequence ID" value="MGG_09005T0"/>
        <property type="gene ID" value="MGG_09005"/>
    </dbReference>
    <dbReference type="GeneID" id="2680128"/>
    <dbReference type="KEGG" id="mgr:MGG_09005"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09005"/>
    <dbReference type="eggNOG" id="KOG3004">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_036204_1_0_1"/>
    <dbReference type="InParanoid" id="A4RCW0"/>
    <dbReference type="OMA" id="RMDWINE"/>
    <dbReference type="OrthoDB" id="437078at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012923">
        <property type="entry name" value="Csm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040038">
        <property type="entry name" value="TIPIN/Csm3/Swi3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13220">
        <property type="entry name" value="TIMELESS INTERACTING-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13220:SF11">
        <property type="entry name" value="TIMELESS-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07962">
        <property type="entry name" value="Swi3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0236">DNA replication inhibitor</keyword>
    <keyword id="KW-0469">Meiosis</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000301720" description="Chromosome segregation in meiosis protein 3">
        <location>
            <begin position="1"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="344"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="357" mass="38598" checksum="8D064B966A99075D" modified="2007-05-15" version="1">MSTSKAKQPSVPALDNYIPDDEDFFDPFASPTNSPNQSPKAKGGAKRSEPDGGLGIDEEVSVAKRARVPRVKLDETRLLSDKGIPALRKRAGTLRLKGKGHEFSDAARLLSFYQLWLDDLFPKAKFLDALAMVEKAGHKTTMHKARTDWINDLKPNMTAPDNDGHADIGHAPVAQPQSSRIAPIFEKRQTIDASTMPAEDSNGVDDLFGGDDLGEMYDVTPKATRPVGEPDDDDIEALMAEAESSIRQPAPIAMSLFGSGRPAKTGTEAQRANGSPNDEDLDAVMAEAEVHTVSHGSSTARKQRAQTDPGNDDDDLEALIAEAEGVLKQKPAPSHKTKDKTSSFDDEEAAMAELDLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKI0</accession>
    <name>G4MKI0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SnodProt1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_05344</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cerato-platanin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710181.1">
        <property type="nucleotide sequence ID" value="XM_003710133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKI0"/>
    <dbReference type="SMR" id="G4MKI0"/>
    <dbReference type="STRING" id="242507.G4MKI0"/>
    <dbReference type="GeneID" id="2676149"/>
    <dbReference type="KEGG" id="mgr:MGG_05344"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05344"/>
    <dbReference type="eggNOG" id="ENOG502SQTH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111635_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKI0"/>
    <dbReference type="OMA" id="QCGTCYG"/>
    <dbReference type="OrthoDB" id="4898945at2759"/>
    <dbReference type="PHI-base" id="PHI:2118"/>
    <dbReference type="PHI-base" id="PHI:5540"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22778">
        <property type="entry name" value="DPBB_CEPL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.10:FF:000009">
        <property type="entry name" value="Allergenic cerato-platanin Asp F13 (AFU_orthologue AFUA_2G12630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010829">
        <property type="entry name" value="Cerato-platanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07249">
        <property type="entry name" value="Cerato-platanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465747" evidence="4">
        <location>
            <begin position="19"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA57569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="137" mass="14205" checksum="EBD30348B20286AB" modified="2011-12-14" version="1">MQFSNILSIFTLAAAAQAVSVSYDTGYDDGSRSLTAVSCSDGANGLITKYGWQTQGQIRNFPYIGGVDAVGGWNSPSCGTCWQLTYNGKSINVLAIDHASGFNIGLAAMNDLTNGQAGSLGRIEAQSQQVGLNACGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKP1</accession>
    <name>G4MKP1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709343.1">
        <property type="nucleotide sequence ID" value="XM_003709295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKP1"/>
    <dbReference type="GeneID" id="12984443"/>
    <dbReference type="KEGG" id="mgr:MGG_16143"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16143"/>
    <dbReference type="HOGENOM" id="CLU_1603059_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKP1"/>
    <dbReference type="OrthoDB" id="10475798at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="166" mass="17479" checksum="7B660BD524FE4E4F" modified="2011-12-14" version="1">MWVVLDLSTSATIMSCHPCHGRTRPGLGGGGSGALASFGRGKVPTRPQEGGKARVRLATRKDAKCIGWESLVQDARAMVTIGGLGASRGTFVTNGKAPTTLKIRLPPRIASGGQAINGAHPWFRGLRAAGSRRFGTGIYNMVTTNVVDTCRSYAGEQFPILLRANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML68</accession>
    <name>G4ML68_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF866 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0587 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709416.1">
        <property type="nucleotide sequence ID" value="XM_003709368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML68"/>
    <dbReference type="SMR" id="G4ML68"/>
    <dbReference type="FunCoup" id="G4ML68">
        <property type="interactions" value="554"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ML68"/>
    <dbReference type="GeneID" id="2684878"/>
    <dbReference type="KEGG" id="mgr:MGG_06705"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06705"/>
    <dbReference type="eggNOG" id="KOG1296">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114688_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML68"/>
    <dbReference type="OMA" id="TAHFVWR"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008584">
        <property type="entry name" value="CXXC_Zn-binding_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857:SF0">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05907">
        <property type="entry name" value="CXXC_Zn-b_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141678">
        <property type="entry name" value="MAL13P1.257-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="18031" checksum="6FD647A31AF78A1F" modified="2011-12-14" version="1">MFSLTLTAELGGVTNLRPDDTEASPFWYTFKVQCTSCRETHANWVGVSRFETNEMSGSRGEANFVWKCKNCKRESSASIKAAPAAYEASEPAKGQKIIEFDCRGLEFVEFKPEGNWLAEGVESGTKFTEIDLDEGEWFEYDEKAGDEVSIKDLKWEISRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLT2</accession>
    <name>G4MLT2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05457</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710322.1">
        <property type="nucleotide sequence ID" value="XM_003710274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLT2"/>
    <dbReference type="SMR" id="G4MLT2"/>
    <dbReference type="GeneID" id="2675885"/>
    <dbReference type="KEGG" id="mgr:MGG_05457"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05457"/>
    <dbReference type="eggNOG" id="ENOG502R9AJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041041_1_1_1"/>
    <dbReference type="InParanoid" id="G4MLT2"/>
    <dbReference type="OMA" id="HNDMGCD"/>
    <dbReference type="OrthoDB" id="272271at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF54">
        <property type="entry name" value="FAMILY OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="2">
        <location>
            <begin position="103"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="464" mass="50763" checksum="6197FC5A67894939" modified="2011-12-14" version="1">MSFSQTLCENMISTQQVRSRSASVSSQLSVTLRSSEATETTDPAHTADCVAQLPKEVTGNLVWSGTDASAPVNHVIQLDVADVLEIENAVVSFKARELHGDKVSCETFPLSDNLSARLRSASDAVHTKQGFCVLRGLEASRYSAEDNTLIFLGVASHIGNVRGIQDGNGNMLSHVTSSKAWESLPDRLRHGVHTNKSMPFHNDMGADILCLHYRQVAKEGGFIHLSSVATIYNELAAKYPDVLEVLATPNWPIQITKTRLRHFLASLISYHDGKVIASLDPGRLGRQQANPEHVPNKASTVAGSSLFRVPTLTQVQRDALAVFDQLAHKHKISVGAQAGDILFVNNLALVHARDAYTDEEAVGGQRRHAVRMWLHDEKLAWSRPAGMRAPWLAAFGYYFKPQGAVVDGAEDGSSARARRVVNRKYPIVPAVDYRIPKYTAGSAAFVLDSSDDEVEYLDDDSDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLX3</accession>
    <name>G4MLX3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_16575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711152.1">
        <property type="nucleotide sequence ID" value="XM_003711104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLX3"/>
    <dbReference type="STRING" id="242507.G4MLX3"/>
    <dbReference type="GeneID" id="12986951"/>
    <dbReference type="KEGG" id="mgr:MGG_16575"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16575"/>
    <dbReference type="eggNOG" id="ENOG502SFU8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_760907_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLX3"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="313"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA58540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="364" mass="41047" checksum="6DAEB32FBFF30556" modified="2011-12-14" version="1">MLERRRLSNALFQVADLRSEIGISAIKDLYGLLKNDCQVAYQPSLRPIDGRCPRKECNVEIDSWKKHIHECFFSYINKSGSQTELHCPDPLCSTEYDSTEDLWYHLQDAHSYPSPKAGCRLKTEKDPFMRDYAAPNPHQPKRRRIREISTDVIKEDPFETQSETICTTPSTLSILSTSCDSFDASTPVPPISEDGSHYAAKQKFLQLETSALTALAESNSISGNFKVVNTGLNINSITSMEETGCSSSNNNTSHLDPSSNSKICEPVKILGFAVELADPDLLGVTTSHNLFPDKVPLQTKSQPIAIDEEQDIWEAEKLLAKRRRGREIQYLVKWKGFPDDDNTWEPTKNIFDKHLIKSFNSSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM23</accession>
    <name>G4MM23_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709520.1">
        <property type="nucleotide sequence ID" value="XM_003709472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM23"/>
    <dbReference type="SMR" id="G4MM23"/>
    <dbReference type="GeneID" id="12984535"/>
    <dbReference type="KEGG" id="mgr:MGG_16170"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16170"/>
    <dbReference type="HOGENOM" id="CLU_3143413_0_0_1"/>
    <dbReference type="InParanoid" id="G4MM23"/>
    <dbReference type="OrthoDB" id="10285187at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="49" mass="5696" checksum="B40A2D3F1EEB1076" modified="2011-12-14" version="1">MASTDLTRALCFMIEENFAQKQMLREKCAIIEVFQNQVQELQIGNGLQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM78</accession>
    <name>G4MM78_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_05505</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Vacuole membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ATG22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710371.1">
        <property type="nucleotide sequence ID" value="XM_003710323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM78"/>
    <dbReference type="STRING" id="242507.G4MM78"/>
    <dbReference type="GeneID" id="2675819"/>
    <dbReference type="KEGG" id="mgr:MGG_05505"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05505"/>
    <dbReference type="eggNOG" id="ENOG502QTJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017518_2_0_1"/>
    <dbReference type="InParanoid" id="G4MM78"/>
    <dbReference type="OMA" id="VGIYLFW"/>
    <dbReference type="OrthoDB" id="42657at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF5">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="532"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA57759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="567" mass="61819" checksum="FCF7E44A6DECC698" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMA0</accession>
    <name>G4MMA0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710393.1">
        <property type="nucleotide sequence ID" value="XM_003710345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMA0"/>
    <dbReference type="GeneID" id="12986312"/>
    <dbReference type="KEGG" id="mgr:MGG_16391"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16391"/>
    <dbReference type="HOGENOM" id="CLU_2146352_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMA0"/>
    <dbReference type="OMA" id="WAYRTAR"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="112" mass="11923" checksum="401B1339B52360E7" modified="2011-12-14" version="1">MKLVNMRGPCSPFATCQPRTGQAVDAHCSFEWVSCICPKKVSWGLAVWDSGKVGKKNPTDQRKWTPNFKGLWAYRTARAGGQTGVPSLADFDSIQGLQAPPSAGAAVGGLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMA4</accession>
    <name>G4MMA4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708702.1">
        <property type="nucleotide sequence ID" value="XM_003708654.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708703.1">
        <property type="nucleotide sequence ID" value="XM_003708655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMA4"/>
    <dbReference type="SMR" id="G4MMA4"/>
    <dbReference type="GeneID" id="12985648"/>
    <dbReference type="KEGG" id="mgr:MGG_15986"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15986"/>
    <dbReference type="eggNOG" id="ENOG502SYTK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122022_0_0_1"/>
    <dbReference type="OrthoDB" id="3555737at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="206" mass="22741" checksum="28650545ED5EF402" modified="2011-12-14" version="1">MPSCSYCESRGMVRCAVSPQDSSRCIECLRVNRSGCDVLGVSNAQLRNIGRQHSKLDAEVEALEEDILAEQQRIQEKQLKLLRLRKQKKLWFEKMMRAVSRGIDDLEELDRVEREEAEQEERRRSAEVLPEVSLESLLPDSNFVWDSIFPMGPLNPSLLDEMNVFAQHSVGSSGGMVSSPGRPLTSGNDPTPDSTGGAVPGNPGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMB1</accession>
    <name>G4MMB1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type-1 protein geranylgeranyltransferase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_01971</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708709.1">
        <property type="nucleotide sequence ID" value="XM_003708661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMB1"/>
    <dbReference type="SMR" id="G4MMB1"/>
    <dbReference type="FunCoup" id="G4MMB1">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MMB1"/>
    <dbReference type="GeneID" id="2681090"/>
    <dbReference type="KEGG" id="mgr:MGG_01971"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01971"/>
    <dbReference type="eggNOG" id="KOG0367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028946_2_0_1"/>
    <dbReference type="InParanoid" id="G4MMB1"/>
    <dbReference type="OMA" id="PRSANHH"/>
    <dbReference type="OrthoDB" id="24893at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF4">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="8">
        <location>
            <begin position="11"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="374" mass="41274" checksum="EE432CB949200D60" modified="2011-12-14" version="1">MFAQQQGNGSLDLAKHLRYFTRCMRTLLPQQYTSNDSTRMALGFFIISGIDLLTQDASSTDPKNSKNASSISATDRSNFRDWVLSCQHTAGGFAGSTTHTLPPHEYDGWDFGSLRTEPGNSNCSNIAATAFALLLLALLADQASGEAVFYGVDRVATLRWLKKLQRPDGSFGEVLVDIPNIDSHDANKKGPGSVTETIAGGRDMRYCYLAAIIRWILRGDMQPEDPGWVEDIDVEALVRHIRAGQTFDGGVAESSMHESHAGYAYCAVSALSLLSRPLEGNVAETQTGPPQSSVNIPYILHFLASRQFEYTDVLSDEDDDEENFFQPDSLSRLSLTDEYPPFVGFNGRVNKVADTCYSPRVSMYPWRRSRLAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMD2</accession>
    <name>G4MMD2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708730.1">
        <property type="nucleotide sequence ID" value="XM_003708682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMD2"/>
    <dbReference type="GeneID" id="2681108"/>
    <dbReference type="KEGG" id="mgr:MGG_01989"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01989"/>
    <dbReference type="eggNOG" id="ENOG502RN1K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_507183_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMD2"/>
    <dbReference type="OMA" id="HKNATHE"/>
    <dbReference type="OrthoDB" id="5204642at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="554" mass="61756" checksum="E86CF2F1FDEDF9E8" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMI7</accession>
    <name>G4MMI7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine(10)-N(2))-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.214</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_06857</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.214" evidence="9"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709577.1">
        <property type="nucleotide sequence ID" value="XM_003709529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMI7"/>
    <dbReference type="FunCoup" id="G4MMI7">
        <property type="interactions" value="817"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MMI7"/>
    <dbReference type="GeneID" id="2685030"/>
    <dbReference type="KEGG" id="mgr:MGG_06857"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06857"/>
    <dbReference type="eggNOG" id="KOG2671">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029646_3_0_1"/>
    <dbReference type="InParanoid" id="G4MMI7"/>
    <dbReference type="OMA" id="AFNKWSR"/>
    <dbReference type="OrthoDB" id="296065at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160102">
        <property type="term" value="F:tRNA (guanine(10)-N2)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016691">
        <property type="entry name" value="TRMT11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059073">
        <property type="entry name" value="TRMT11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370">
        <property type="entry name" value="RNA METHYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370:SF3">
        <property type="entry name" value="TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25904">
        <property type="entry name" value="Tmrp11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017259">
        <property type="entry name" value="tRNA_mtfrase_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51627">
        <property type="entry name" value="SAM_MT_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA (guanine(10)-N(2))-methyltransferase TRMT11 N-terminal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA56965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="459" mass="50870" checksum="E6661544274BF400" modified="2011-12-14" version="1">MDFLIRFGGVHETFRLVEIQALAIVENVRMEVVFYNADSPFCIVKLDSSAAAAALISRSILSQSIHELWAMGDDYAALHADTKTRSAHLWPAHEKASWRFDVDSYRGARNQDAIVSIINSFAYLPLRGPIRMRGADTELTVMEHWAHDAVPLGLEHPERLYLARKVASSPRNDLIRKYDLKKRRYISTTSMDSELALVTANIALAAPGRLFYDPFVGTGSFPVAAAQWGALAWGSDIDGRAVRGDEGGVGGKTLRGNFEQYGLLHGLADSFSADLTNSPVVRCQLGSGGGGRRWLDGIICDPPYGVREGLRVLGVRDAEKQAHVVKAGMNMYRDPDFIPPKRPYSFLAMLDDLLTFAAETLIDGGRLAFWMPTANDESLELAVPTHPCMRTVAVCVQVFNKWSRRLITYERIPDNQVDTEALALALANRDAGEGEQGTTADELNPFRRGYFTKFKTEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MML7</accession>
    <name>G4MML7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_05533</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710401.1">
        <property type="nucleotide sequence ID" value="XM_003710353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MML7"/>
    <dbReference type="SMR" id="G4MML7"/>
    <dbReference type="FunCoup" id="G4MML7">
        <property type="interactions" value="572"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MML7"/>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="GeneID" id="2675809"/>
    <dbReference type="KEGG" id="mgr:MGG_05533"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05533"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_1_1_1"/>
    <dbReference type="InParanoid" id="G4MML7"/>
    <dbReference type="OMA" id="QCPRGAQ"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF384">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465851" description="chitinase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="14">
        <location>
            <begin position="47"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA57789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="436" mass="47222" checksum="E9ED67A83C175DC2" modified="2011-12-14" version="1">MRPTTLVLPLAVLAGSVTARLTRPEGRGLQSREAPQDITPNRDSSAYRSVAYVTNWSIYGAKFLPEQIAVDSISHVQYAFADILANGTVVSSDAWADTQKQFGNGTQGGNSSDAHGLVEQLYKIKQANRNVKMLLSIGGYTWSPKFVPVAADAGKRAAFVSSAVALMGDWGMDGLDVDWEYPDTAETNKNCVLLLQELRRGLDDYSQQHTGSQYKFSLSMPAPAGPTHYAAFDFKAMDASLDFWSIMAFDFAGSWDNTTGHQANVYPGPDLTTKASIDVAVSDYVKAGVAPGKINLGLPLYGRSFDKTTGLGKGYTASTAGSLEGQAGIWIYKDLPRAGATVLYDDVAKASYTMDNSTGQLISYDDLKSVQFKSDYVKQKQIGGVMFWESSQDRPGSDSIVRTMARSLGKLESAQNWLSYPGSQYANIKNNMGQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMV0</accession>
    <name>G4MMV0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708792.1">
        <property type="nucleotide sequence ID" value="XM_003708744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMV0"/>
    <dbReference type="GeneID" id="2681318"/>
    <dbReference type="KEGG" id="mgr:MGG_02041"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02041"/>
    <dbReference type="HOGENOM" id="CLU_1332150_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMV0"/>
    <dbReference type="OMA" id="TANCASK"/>
    <dbReference type="OrthoDB" id="5234017at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="23625" checksum="7AA6FE2531DD3441" modified="2011-12-14" version="1">MNDQLSLRTRPFRCIGSYTMAEKGDNNDNLNDRIPFQAQPKSKFPDPSCLNGIARRPPTSTANCASKEAKAKYCGRPIADYGTACVDRKVRTRRKTYAAQREKVPGAKRQKKKKQSTKLLPGGLYHGRWRPGIYWPVVILSWDDARVDMKDLPKSDCFDVDNEKIVGWAPGYENGGILAYDRWFPVVYLDKDYCIGWMHAKDFFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN89</accession>
    <name>G4MN89_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708824.1">
        <property type="nucleotide sequence ID" value="XM_003708776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN89"/>
    <dbReference type="GeneID" id="12985690"/>
    <dbReference type="KEGG" id="mgr:MGG_16024"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16024"/>
    <dbReference type="HOGENOM" id="CLU_2558712_0_0_1"/>
    <dbReference type="InParanoid" id="G4MN89"/>
    <dbReference type="OrthoDB" id="5247442at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="82" mass="9649" checksum="FA3ABA6654FF8E3C" modified="2011-12-14" version="1">MFENFVELLGEKYGFGAIVNTQPRATVINWAYFVRRYFERPKINYWVVLKVKSYIAMKAPVKLVMVGSRRKKERRAARAGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNS6</accession>
    <name>G4MNS6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708904.1">
        <property type="nucleotide sequence ID" value="XM_003708856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNS6"/>
    <dbReference type="SMR" id="G4MNS6"/>
    <dbReference type="STRING" id="242507.G4MNS6"/>
    <dbReference type="MEROPS" id="S12.950"/>
    <dbReference type="GeneID" id="5049475"/>
    <dbReference type="KEGG" id="mgr:MGG_13715"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13715"/>
    <dbReference type="eggNOG" id="ENOG502QQGR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_11_1_1"/>
    <dbReference type="InParanoid" id="G4MNS6"/>
    <dbReference type="OMA" id="DKACEDQ"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF3">
        <property type="entry name" value="BETA-LACTAMASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G07500)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="24"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="412" mass="44674" checksum="E3181C24A91264C3" modified="2011-12-14" version="1">MPISTEAVSSLKAIVDGACADPTTDIPGAVVVIVDRDGQELLAHAAGVRGLSAADGHRQPMTLDTVFWIASCTKLLAGIACMQLVERGVLRLDDGDQIEELCPELARLKVLGKDGVLVDKTNKISLRMLLTHTAGFGYTFFNERLRDWSLPTGVDEFSGRIEDVTTPLLFQPGEGWEYGVGIDWAGIALERATGLKLNEFLQHNVFEPLGIKDMSMVPGDEMRSRLAHMHHREGDGKLRPRDHPLRAPLVVDVHNKSDVARLHNSGGAGMFATAQEYCKVLATILNDGKSPTTGVRILRPDTVAEMFRNQIPQFPDFGRQGIPAAKPDLTNPIAELYPVEGGAPQGWGLTFLQPSGADAGTVCWAGLPNLWWWLNREKGVAGLVATQILPFVDPKVMGLWFGVQGASYAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPF6</accession>
    <name>G4MPF6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Nitrogen permease regulator 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Required for meiotic nuclear division protein 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_05712</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Vacuole membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the NPR3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710611.1">
        <property type="nucleotide sequence ID" value="XM_003710563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPF6"/>
    <dbReference type="FunCoup" id="G4MPF6">
        <property type="interactions" value="95"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MPF6"/>
    <dbReference type="GeneID" id="2675908"/>
    <dbReference type="KEGG" id="mgr:MGG_05712"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05712"/>
    <dbReference type="eggNOG" id="KOG3830">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014314_2_0_1"/>
    <dbReference type="InParanoid" id="G4MPF6"/>
    <dbReference type="OMA" id="WNHDDHL"/>
    <dbReference type="OrthoDB" id="18648at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056603">
        <property type="entry name" value="HTH_NPRL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005365">
        <property type="entry name" value="Npr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153">
        <property type="entry name" value="CGTHBA PROTEIN -14 GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13153:SF5">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24064">
        <property type="entry name" value="HTH_NPRL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03666">
        <property type="entry name" value="NPR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="GATOR1 complex protein NPRL3 C-terminal HTH" evidence="7">
        <location>
            <begin position="808"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="212"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="589"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="767"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="597"/>
            <end position="610"/>
        </location>
    </feature>
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        <location>
            <begin position="620"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="630"/>
            <end position="644"/>
        </location>
    </feature>
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        <location>
            <begin position="645"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="685"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="785"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA57999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="859" mass="95430" checksum="D22F59DAB1FB3B4E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPU9</accession>
    <name>G4MPU9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709858.1">
        <property type="nucleotide sequence ID" value="XM_003709810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPU9"/>
    <dbReference type="SMR" id="G4MPU9"/>
    <dbReference type="GeneID" id="2680176"/>
    <dbReference type="KEGG" id="mgr:MGG_09236"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09236"/>
    <dbReference type="eggNOG" id="ENOG502SDCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012103_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPU9"/>
    <dbReference type="OMA" id="EYSVHVN"/>
    <dbReference type="OrthoDB" id="2555519at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38701">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38701:SF1">
        <property type="entry name" value="UP-REGULATED DURING SEPTATION PROTEIN 1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="580"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="676"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="833"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="623"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="71"/>
            <end position="112"/>
        </location>
    </feature>
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        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="510"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="580"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="679"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="692"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="718"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="856" mass="91071" checksum="EE1A923E8DE92E73" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ80</accession>
    <name>G4MQ80_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Kinesin-II 85 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_09255</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709885.1">
        <property type="nucleotide sequence ID" value="XM_003709837.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MQ80"/>
    <dbReference type="STRING" id="242507.G4MQ80"/>
    <dbReference type="GeneID" id="2680191"/>
    <dbReference type="KEGG" id="mgr:MGG_09255"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09255"/>
    <dbReference type="eggNOG" id="KOG0245">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001485_20_2_1"/>
    <dbReference type="InParanoid" id="G4MQ80"/>
    <dbReference type="OMA" id="IDRGAKC"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="P:vesicle transport along microtubule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="5"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="13">
        <location>
            <begin position="1566"/>
            <end position="1736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="625"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1415"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1454"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1620"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1738"/>
            <end position="1771"/>
        </location>
    </feature>
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        <location>
            <begin position="429"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="751"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1422"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1481"/>
            <end position="1491"/>
        </location>
    </feature>
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        <location>
            <begin position="1738"/>
            <end position="1747"/>
        </location>
    </feature>
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        <location>
            <begin position="99"/>
            <end position="106"/>
        </location>
        <ligand>
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        </ligand>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA57273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1771" mass="195870" checksum="A31B1AB0D77C8A99" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQS1</accession>
    <name>G4MQS1_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003709922.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="mgr:MGG_16282"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16282"/>
    <dbReference type="InParanoid" id="G4MQS1"/>
    <dbReference type="OrthoDB" id="5265256at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="230" mass="25186" checksum="64954BE5178DC503" modified="2011-12-14" version="1" fragment="single">MEDSPMSGLPGPIPPDRGPESSPNEVLTAKLQAQDLQLKALTTQLDQLQHTIQQLTSLLTLKNGEPTSFSGIAGINTPNSGNLEANPQIFSANTATAPPNPPGNLILGDGIESIAWHSSPVTAYKTLEDSYSVAPEISRDSLYREFHALNFSKFRGSIPEFNSRFNSLVARLANANVQISPIDVRNQYLRALEGTFPTWTERQRSTQRALQAIGQNSDRLNLQYLMADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRP0</accession>
    <name>G4MRP0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protoplast regeneration and killer toxin resistance</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA57463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_10646"/>
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        <property type="entry name" value="TPR-like_helical_dom_sf"/>
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    <dbReference type="PANTHER" id="PTHR46430:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATOR SKT5-RELATED"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="1"/>
            <end position="321"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="496"/>
        </location>
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            <begin position="1"/>
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        </location>
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        </location>
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            <begin position="247"/>
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        </location>
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            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
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            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="807"/>
            <end position="818"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA57463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="818" mass="88979" checksum="D0C110061FD6EC45" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRZ5</accession>
    <name>G4MRZ5_PYRO7</name>
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        <submittedName>
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        <name evidence="1" type="ORF">MGG_16130</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003709228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRZ5"/>
    <dbReference type="SMR" id="G4MRZ5"/>
    <dbReference type="GeneID" id="12984410"/>
    <dbReference type="KEGG" id="mgr:MGG_16130"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16130"/>
    <dbReference type="HOGENOM" id="CLU_3014640_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRZ5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="56" mass="5930" checksum="46A1723213B9130A" modified="2011-12-14" version="1">MSGFGNAIALLFKLRSKPQTASTIANARHSVAHAKLGRSDLVLGSSKHTRVYGYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSB4</accession>
    <name>G4MSB4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 16">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_04438</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="function">
        <text evidence="16">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA53726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003713485.1"/>
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    </dbReference>
    <dbReference type="STRING" id="242507.G4MSB4"/>
    <dbReference type="GeneID" id="2677835"/>
    <dbReference type="KEGG" id="mgr:MGG_04438"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04438"/>
    <dbReference type="eggNOG" id="KOG0070">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_040729_9_3_1"/>
    <dbReference type="InParanoid" id="G4MSB4"/>
    <dbReference type="OMA" id="HYYANTN"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
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        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SAR1GTPBP"/>
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        <property type="entry name" value="ARF"/>
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    </dbReference>
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        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 16" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 13 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 16" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 13 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 16" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
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        <source>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022707"/>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
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    </evidence>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00053326"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00070396"/>
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    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
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            <dbReference type="PIRSR" id="PIRSR606689-2"/>
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        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA53726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="183" mass="20944" checksum="384012FC1403FD5A" modified="2011-12-14" version="1">MGLSISKLFDRLWGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNIQFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRIVEAREELQRMLNEDELRDAILLVFANKQDLPNAMNAAEITDKLGLHSLRQRAWYIQSTCATSGDGLYEGLEWLATTLRKAGHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSH9</accession>
    <name>G4MSH9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Karyopherin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_01449</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA54595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003714354.1"/>
    </dbReference>
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    <dbReference type="SMR" id="G4MSH9"/>
    <dbReference type="FunCoup" id="G4MSH9">
        <property type="interactions" value="1204"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSH9"/>
    <dbReference type="GeneID" id="2679701"/>
    <dbReference type="KEGG" id="mgr:MGG_01449"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01449"/>
    <dbReference type="eggNOG" id="KOG2081">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005996_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSH9"/>
    <dbReference type="OMA" id="LECITSW"/>
    <dbReference type="OrthoDB" id="435593at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="mRNA transport regulator MTR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
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        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
    </dbReference>
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        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
    </dbReference>
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        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
    </dbReference>
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        <property type="entry name" value="MRNA TRANSPORT REGULATOR MTR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IBN_N"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
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    </dbReference>
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        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="3">
        <location>
            <begin position="33"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="971" mass="109592" checksum="EF7A7FF8EC63C3A6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSI9</accession>
    <name>G4MSI9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714412.1">
        <property type="nucleotide sequence ID" value="XM_003714364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSI9"/>
    <dbReference type="SMR" id="G4MSI9"/>
    <dbReference type="STRING" id="242507.G4MSI9"/>
    <dbReference type="GeneID" id="5051176"/>
    <dbReference type="KEGG" id="mgr:MGG_11206"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11206"/>
    <dbReference type="eggNOG" id="ENOG502QQV3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1788160_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSI9"/>
    <dbReference type="OrthoDB" id="2422440at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="118" mass="13096" checksum="E9E6FB0EB4437C6E" modified="2011-12-14" version="1">MVASVKALKDNGMVSKARRQSQVEAQGTDTGTSGVGSADERIRGDLRRELAKLKEDYSKLKTDSEKEIEDLKKQVSEKDKMIKKFEMFIDLCNQRVMVQRELLNDGNEGGSAAVNSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSU6</accession>
    <name>G4MSU6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HNRNP arginine N-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_04584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713607.1">
        <property type="nucleotide sequence ID" value="XM_003713559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSU6"/>
    <dbReference type="SMR" id="G4MSU6"/>
    <dbReference type="FunCoup" id="G4MSU6">
        <property type="interactions" value="920"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSU6"/>
    <dbReference type="GeneID" id="2678111"/>
    <dbReference type="KEGG" id="mgr:MGG_04584"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04584"/>
    <dbReference type="eggNOG" id="KOG1499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017375_1_2_1"/>
    <dbReference type="InParanoid" id="G4MSU6"/>
    <dbReference type="OMA" id="CTHTKVK"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="PHI-base" id="PHI:11055"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035241">
        <property type="term" value="F:protein-arginine omega-N monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060567">
        <property type="term" value="P:negative regulation of termination of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000001">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000050">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="5">
        <location>
            <begin position="64"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="6">
        <location>
            <begin position="166"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA53800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="345" mass="39424" checksum="9B609A7D8ABA2510" modified="2011-12-14" version="1">MAGDAMDVEKAEQKLKSMDHSEQHYFNSYNHHGIHEEMLKDEVRTKSYMNAIVQNKHLFKDKVVLDVGCGTAILSMFAVKAGAKHVIGVDMSTIIFKAREIVARNGMADKITLIQGKMEEIEMPFPHVDIIISEWMGYFLLYESMLDTVLYARDRYLVKDGLIFPDKAIIYAAGIEDGEYKDEKIGFWDNVYGFDYTPLKETALSEPLVDTVDIKAVVTDPAPVLTLDLYKCTTADLAFSIPFSLTARRDDFIHALVSWFDIEFAACHKPIRFSTGPHTKYTHWKQTVFYLNEVVTVHQGEEVKCNLQVKPNDKNRRDLDIKLDYTLETQDQTRTAGGECTYKMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTC1</accession>
    <name>G4MTC1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713674.1">
        <property type="nucleotide sequence ID" value="XM_003713626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTC1"/>
    <dbReference type="GeneID" id="12987172"/>
    <dbReference type="KEGG" id="mgr:MGG_15556"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15556"/>
    <dbReference type="HOGENOM" id="CLU_2904645_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTC1"/>
    <dbReference type="OrthoDB" id="10477412at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="62" mass="6823" checksum="23998ACE8720AB28" modified="2011-12-14" version="1">MYWLGAPVNSSAPRGTLRRTGYDSFVPGLPGHSLAQASFPVLARFESVPNEAMFWFVLDCFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUC6</accession>
    <name>G4MUC6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Chromatin modification-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_01632</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Component of an histone acetyltransferase complex.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in cell cycle progression and meiosis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="16">The PHD-type zinc finger mediates the binding to H3K4me3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the ING family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714620.1">
        <property type="nucleotide sequence ID" value="XM_003714572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUC6"/>
    <dbReference type="SMR" id="G4MUC6"/>
    <dbReference type="FunCoup" id="G4MUC6">
        <property type="interactions" value="280"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUC6"/>
    <dbReference type="GeneID" id="2679106"/>
    <dbReference type="KEGG" id="mgr:MGG_01632"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01632"/>
    <dbReference type="eggNOG" id="KOG1973">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031900_7_0_1"/>
    <dbReference type="InParanoid" id="G4MUC6"/>
    <dbReference type="OMA" id="YEWFHWK"/>
    <dbReference type="OrthoDB" id="2505961at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16858">
        <property type="entry name" value="ING_ING3_Yng2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF100">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN YNG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 16" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3 14 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 16" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="18">
        <location>
            <begin position="403"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="133"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="220"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="386"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="13">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="13">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="13">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <feature type="site" description="Histone H3K4me3 binding" evidence="13">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR628651-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA54813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="464" mass="49454" checksum="AE4C3ADCFACAE274" modified="2011-12-14" version="1">MPRDDLSIDFVKRMPQGESIDPSLILDDWINRVQNLPEEIRFIQDEILDKDRQYNDCIKIIEDRDSRIQKYIKAHGSHAENPKEASLRATIRENYATADRLAGEKVALSERMKLIMDKHVRELDKQLKILTDRNEPGFTDPDELPSLLRPNANPPPTTSRVSLTVNTNIPHSQSQTSATTTATARAGNSSIRTAQTLHNSASAPATPAAGIILGRQAREVSAGPSGGVPKRGPRINGGAGSAATPTSNLARHSSLGPGTPKGHTATGVQRAGSAGPRASSKGAAAASSGRKGTPSSTGGRKKTPGASGGTTKSGLSRVKRVAKNSPSSNADSELSDDMSASGDEVRSRTGTPSAPTSVPSRKDGGAHGEGLASGATLLKKERHGSDDDEEMVDPEDEEAGDDRKYCLCQNVSFGNMVACDNPDCPLEWFHWSCVDLKSEPAGAWFCPRCREDPKVLAKAGNKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUI6</accession>
    <name>G4MUI6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Dihydroorotate dehydrogenase (fumarate)</fullName>
            <ecNumber evidence="11">1.3.98.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_07263</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(S)-dihydroorotate + fumarate = orotate + succinate</text>
            <dbReference type="Rhea" id="RHEA:30059"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="EC" id="1.3.98.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.98.1" evidence="11"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715485.1">
        <property type="nucleotide sequence ID" value="XM_003715437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUI6"/>
    <dbReference type="SMR" id="G4MUI6"/>
    <dbReference type="FunCoup" id="G4MUI6">
        <property type="interactions" value="686"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUI6"/>
    <dbReference type="GeneID" id="2683009"/>
    <dbReference type="KEGG" id="mgr:MGG_07263"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07263"/>
    <dbReference type="eggNOG" id="KOG1436">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036010_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUI6"/>
    <dbReference type="OMA" id="GDGYRRM"/>
    <dbReference type="OrthoDB" id="14784at2759"/>
    <dbReference type="UniPathway" id="UPA00070"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990663">
        <property type="term" value="F:dihydroorotate dehydrogenase (fumarate) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04741">
        <property type="entry name" value="DHOD_1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.26.10">
        <property type="entry name" value="Dihydroorotate Dehydrogenase A, chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033886">
        <property type="entry name" value="DHOD_1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023359">
        <property type="entry name" value="Dihydro_DH_chainA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF1">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (FUMARATE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="12">
        <location>
            <begin position="86"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA55678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="343" mass="36243" checksum="1401A0BE823BDB13" modified="2011-12-14" version="1">MGSIQDEQRRPPPLQIYPPLVNSATPWATTLKDLNRLYSCPHTGAVTTRTSLIHGFPHDPEVHQHALYDTVAVSGALPRGTSNASFNSLGYSPILLSEYLSFIETISSQQELGSRSKTFIVSVTGTPQEIAACYGMVSATQAKVKTPLALELNLSCPNISGKPPPAYDGPSLLEYITWLSDLGPTGPVIPVGIKTPPYTHSTQYETLISALIAGSPTGLCPISFITSTNTLGSCLMLTSLDGHKGQGQQPHKNVLPGNGLGGMAGTPLHPLSLGNVATIRRLLDEQPDMLGHIQIVGVGGVCDSGGYRRMRSVGAAVVGVGTGLGIKGVKVFEDIAMDVHDNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUS9</accession>
    <name>G4MUS9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Infection structure specific protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714666.1">
        <property type="nucleotide sequence ID" value="XM_003714618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUS9"/>
    <dbReference type="GeneID" id="2679355"/>
    <dbReference type="KEGG" id="mgr:MGG_01678"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01678"/>
    <dbReference type="eggNOG" id="ENOG502T46V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117760_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUS9"/>
    <dbReference type="OMA" id="MSAVKEC"/>
    <dbReference type="OrthoDB" id="3561078at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465357" description="Infection structure specific protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="21250" checksum="0FDE3330721E98CF" modified="2011-12-14" version="1">MHSNTVLFMIAAATGVMSAELNLFPGHAVVRREGAARETASPSLPSINDPCLASLMSISKTLPTPGADILSALASNTETNACSITVAASVSDKFNAYTSTIRSWYSSNSAAINSVLSQCPKLSSYAGDLPVCTGKDSSNGASSTATKGSSGAATTTGRATDAGSGSATAATASAGDSSSNPTGSAASVTKSGSGPRETNFVAGAVAAIGFLGVVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV61</accession>
    <name>G4MV61_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exosome complex component RRP45</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Ribosomal RNA-processing protein 45</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_08860</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713883.1">
        <property type="nucleotide sequence ID" value="XM_003713835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV61"/>
    <dbReference type="SMR" id="G4MV61"/>
    <dbReference type="FunCoup" id="G4MV61">
        <property type="interactions" value="920"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MV61"/>
    <dbReference type="GeneID" id="2679846"/>
    <dbReference type="KEGG" id="mgr:MGG_08860"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08860"/>
    <dbReference type="eggNOG" id="KOG1614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038194_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV61"/>
    <dbReference type="OMA" id="GPQFENG"/>
    <dbReference type="OrthoDB" id="10264038at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11368">
        <property type="entry name" value="RNase_PH_RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.70:FF:000005">
        <property type="entry name" value="Exosome complex component RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033100">
        <property type="entry name" value="Rrp45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF14">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7" id="KW-0271">Exosome</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="11">
        <location>
            <begin position="32"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="12">
        <location>
            <begin position="191"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00077933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA54076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="293" mass="32495" checksum="C438EC36E2F63952" modified="2011-12-14" version="1">MPREAEPSLNEKAFLLQALQQNLRLDGRDIDEYRPIKLSFGDEYGLVEVEFGKTRIVAKASAEVTIPYTDRPFDGIFNIVTELSPMASPAFEVNRPTETEVLLSRLLEKTIRRSNALDTESLCLVAGQKCWSIRVDVHAESHDGNLIDASCLAVVAALRHFRKPDTSIEGEVVTVYTPAEREPVPLSWLHSPFCVTFSFFGDLGDMFVVDANWLEEQVRVSSCTISLNRHGEICQIAKLGGTAVEAVTLLQCNAVALVKAKDFSKLLDDKLAEDANKRDRGGLLAELSAENER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVK8</accession>
    <name>G4MVK8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fructose-1,6-bisphosphatase</fullName>
            <ecNumber evidence="5">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_08895</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the FBPase class 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="5"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713924.1">
        <property type="nucleotide sequence ID" value="XM_003713876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVK8"/>
    <dbReference type="SMR" id="G4MVK8"/>
    <dbReference type="FunCoup" id="G4MVK8">
        <property type="interactions" value="567"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MVK8"/>
    <dbReference type="GeneID" id="2679881"/>
    <dbReference type="KEGG" id="mgr:MGG_08895"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08895"/>
    <dbReference type="eggNOG" id="KOG1458">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039977_1_0_1"/>
    <dbReference type="InParanoid" id="G4MVK8"/>
    <dbReference type="OMA" id="YIPENCP"/>
    <dbReference type="OrthoDB" id="10256725at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000009">
        <property type="entry name" value="Fructose-1,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000001">
        <property type="entry name" value="Fructose-1,6-bisphosphatase class 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006778">
        <property type="entry name" value="PRK09293.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF1">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="14">
        <location>
            <begin position="19"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="15">
        <location>
            <begin position="212"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA54117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="344" mass="37668" checksum="D06EA1976F8139F5" modified="2011-12-14" version="1">MADSNNGPETEKVNTNIVTLTRFLTEEQAKHKEATGDFTLLCHALQFSFKAIAYYIRRATLVNLTGLAGSSNTTGDDQKKLDVIGNDLFIEAMRSSGKCALLVSEEEEEIIFFTNGNGSARYAVACDPIDGSSNLDAGVSVGTIFGIHKLAEGSTGSKEDILKPGSELLAAGFTMYGASAQLVLTMKNGGVNGFTLDNAFGEFILTHPDMRMPKSRAIYSVNEGNSLYWEDHVKEYFSSLKHPQEKSGKPYSARYIGSMVADAYRTLLYGGIFAYPADKKSPKGKLRILYECAPMAMVFENAGGQAIDSNMKRMLDVVPEHIHDRSGIFMGSWDEVEKVKAYHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVP3</accession>
    <name>G4MVP3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF292-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IST1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714766.1">
        <property type="nucleotide sequence ID" value="XM_003714718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVP3"/>
    <dbReference type="SMR" id="G4MVP3"/>
    <dbReference type="FunCoup" id="G4MVP3">
        <property type="interactions" value="760"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MVP3"/>
    <dbReference type="GeneID" id="2679493"/>
    <dbReference type="KEGG" id="mgr:MGG_01765"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01765"/>
    <dbReference type="eggNOG" id="KOG2027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037652_2_1_1"/>
    <dbReference type="InParanoid" id="G4MVP3"/>
    <dbReference type="OMA" id="HEVREFT"/>
    <dbReference type="OrthoDB" id="29853at2759"/>
    <dbReference type="PHI-base" id="PHI:123045"/>
    <dbReference type="PHI-base" id="PHI:123046"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.60:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein IST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.60">
        <property type="entry name" value="Vacuolar protein sorting-associated protein Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005061">
        <property type="entry name" value="Ist1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042277">
        <property type="entry name" value="IST1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161">
        <property type="entry name" value="IST1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12161:SF5">
        <property type="entry name" value="IST1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03398">
        <property type="entry name" value="Ist1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="32881" checksum="088D74AF4D1F65F3" modified="2011-12-14" version="1">MAPSASIITKIKVQLKLSIARLRMVQQRDEAASKVQRRAMAQLLDQGKIDSARIRVENIIRSDIQVELYEMLELYCELLLARAGLLDAPTCDPGLEEAAKSVIYAAGKTEIKELQAVRQLLGDKFGKEFVLVATNNSDGKVSEKVVKKLSVTPPREELVAGYLEEIARAYGVNWPRRVEQEQDEEEEEEDEPKFVDDAGEGGGGQAQKADGDAAVAAAAADADKAAPPKSAVQPLQVSPPSPSTENIRPKVTLNKMELKPSKKMVDAGLAKKPTAGGASKPSGDIRDGIPNVDDLAKRFAALKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVP4</accession>
    <name>G4MVP4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Spt3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_01766</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SPT3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714767.1">
        <property type="nucleotide sequence ID" value="XM_003714719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVP4"/>
    <dbReference type="SMR" id="G4MVP4"/>
    <dbReference type="FunCoup" id="G4MVP4">
        <property type="interactions" value="928"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MVP4"/>
    <dbReference type="GeneID" id="2679494"/>
    <dbReference type="KEGG" id="mgr:MGG_01766"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01766"/>
    <dbReference type="eggNOG" id="KOG3902">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038706_1_1_1"/>
    <dbReference type="InParanoid" id="G4MVP4"/>
    <dbReference type="OMA" id="QFMFNEQ"/>
    <dbReference type="OrthoDB" id="66982at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001403">
        <property type="term" value="P:invasive growth in response to glucose limitation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007124">
        <property type="term" value="P:pseudohyphal growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd22926">
        <property type="entry name" value="HFD_SPT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000023">
        <property type="entry name" value="transcription initiation protein SPT3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003195">
        <property type="entry name" value="TFIID_TAF13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380:SF16">
        <property type="entry name" value="TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02269">
        <property type="entry name" value="TFIID-18kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="320" mass="36622" checksum="2728679FE590330D" modified="2011-12-14" version="1">MADKDGKQYKYRQEIQQMMYVSGETGEPSVETTGMIEEIVRQQVIEILRNCTELAARRGSRTITINDLIFQIREDAAKVSRLRTFLSWKDVRKNVKDSDDKGADADIGAGEDPVGGVVAGPVDDAAKKNKKSKVGLPWEPSSFYSQEVPERDDEEDEEEEEMNHITLQRLRKADERTKVMTREEYVTWSEYRQASFTYRKGKRFREWAGFGIVTDGRPSDDIVDILGFLTFEMVQMLTEEALKLKEQEDLWKERTGGGEKTSKQPKIAAHGLFLPPSEGRTPVEARHVQEAFRRMQGRPKKSRAMLNGTRLAQHTALKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWQ6</accession>
    <name>G4MWQ6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DJ-1/PfpI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714918.1">
        <property type="nucleotide sequence ID" value="XM_003714870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWQ6"/>
    <dbReference type="SMR" id="G4MWQ6"/>
    <dbReference type="STRING" id="242507.G4MWQ6"/>
    <dbReference type="GeneID" id="2679473"/>
    <dbReference type="KEGG" id="mgr:MGG_01896"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01896"/>
    <dbReference type="eggNOG" id="ENOG502S46I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_8_1"/>
    <dbReference type="InParanoid" id="G4MWQ6"/>
    <dbReference type="OMA" id="IEYAPHL"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="147"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="324" mass="35424" checksum="FFB2C785C647BF18" modified="2011-12-14" version="1">MARCNNRIWVYIYSSSISFSVLSSSLSRYISCHIETKPQTHTKAHIAMAMRLFLFGLSAAAVLGQSPSYDWGPSLDIGIILFPGFQPLDVIAPADVMMALSGSVNMTISFIWKEAGPVWARSPPRLNPAPPNPNIPAGVFPIQAPSFVATHSFADAPPLDVVLVPGGAGSRVLHDHNDTSVEDFVKERYPTLRYLLSVCTGSGFLAKSGLLDGRRATTNKAAWSWPTQFGTNVTWVPTARWVEDGNIWSSSGVSAGIDMTYAFFSRILDQKLVDRTMNNIEYAPHLDEHWDPYSIVHNVPGADQSQSLGECVGPAGYEFTCNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX28</accession>
    <name>G4MX28_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714933.1">
        <property type="nucleotide sequence ID" value="XM_003714885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX28"/>
    <dbReference type="GeneID" id="12985462"/>
    <dbReference type="KEGG" id="mgr:MGG_15795"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15795"/>
    <dbReference type="eggNOG" id="KOG1075">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046012_0_0_1"/>
    <dbReference type="InParanoid" id="G4MX28"/>
    <dbReference type="OMA" id="FRVFHES"/>
    <dbReference type="OrthoDB" id="4939572at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="495"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="570" mass="62408" checksum="50B88F6EA0F0A63F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXI4</accession>
    <name>G4MXI4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Naringenin 3-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01223</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714122.1">
        <property type="nucleotide sequence ID" value="XM_003714074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXI4"/>
    <dbReference type="SMR" id="G4MXI4"/>
    <dbReference type="STRING" id="242507.G4MXI4"/>
    <dbReference type="GeneID" id="2679557"/>
    <dbReference type="KEGG" id="mgr:MGG_01223"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01223"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010119_1_1_1"/>
    <dbReference type="InParanoid" id="G4MXI4"/>
    <dbReference type="OMA" id="ARETGFF"/>
    <dbReference type="OrthoDB" id="627829at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050295">
        <property type="entry name" value="Plant_2OG-oxidoreductases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47991">
        <property type="entry name" value="OXOGLUTARATE/IRON-DEPENDENT DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="178"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="396" mass="42993" checksum="E696817F0A580768" modified="2011-12-14" version="1">MSFTSIPVLDLSLASSPTTKPAFLADLRSALMEVGFLYLKNVGIPDSLFASAISHGRAFFELPLDEKLKIEMKNAPSFLGYSRLSAEVTAGAIDHREQIDLSTEHVVPTAPDTPRYYNLLGPNQWPDEAALPGFRDTFTAYMTAMGAVSMRFTALVAEAIGLPASAFERYFERSIQDQQHKLKIVKYPDVGELGADGAARQGVGPHKDSMYTSYLLQASGHRGLQVQNLRGDWVDCPPVDGTLVVAIGQGLEALTGGVCASTTHRVLSPAAGEGARFSIPFFQGVRLDTEFEELETAGLGRAVPEEVREQRRRVLLEGSGQRLDDVEFTFRTGGVAKTLGEATLRNRVKSHPDVGERWYPDILASIREEQRIAGRQGAGTSTAPGVEKLRGDAQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXJ7</accession>
    <name>G4MXJ7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714135.1">
        <property type="nucleotide sequence ID" value="XM_003714087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXJ7"/>
    <dbReference type="GeneID" id="12984601"/>
    <dbReference type="KEGG" id="mgr:MGG_15650"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15650"/>
    <dbReference type="HOGENOM" id="CLU_3069178_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXJ7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="53" mass="5907" checksum="E7E5494E71347403" modified="2011-12-14" version="1">MYMHGVFVHASAELHVTVIHRCLCGRYFQPTLNLLLCPGKRGAVKPSVLIELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXT3</accession>
    <name>G4MXT3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15052</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003714979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXT3"/>
    <dbReference type="GeneID" id="12985513"/>
    <dbReference type="KEGG" id="mgr:MGG_15052"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15052"/>
    <dbReference type="HOGENOM" id="CLU_2146356_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXT3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="112" mass="12704" checksum="CB2BAD8C3C4B6245" modified="2011-12-14" version="1">MGFCAFALRIFTQVSSPFANGEIGLADAVDWVRATCSKQLADVSMLYYTPCWPSLARPRCRISGRNRDGTFGHGMLTARFNHSERDKKVIEDEKTKSTNMHPNINFCPMWLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY10</accession>
    <name>G4MY10_PYRO7</name>
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        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10443</name>
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    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA53538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713345.1">
        <property type="nucleotide sequence ID" value="XM_003713297.1"/>
    </dbReference>
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    <dbReference type="SMR" id="G4MY10"/>
    <dbReference type="STRING" id="242507.G4MY10"/>
    <dbReference type="GeneID" id="2682076"/>
    <dbReference type="KEGG" id="mgr:MGG_10443"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10443"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009043_1_0_1"/>
    <dbReference type="InParanoid" id="G4MY10"/>
    <dbReference type="OMA" id="IELCADN"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
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    </dbReference>
    <dbReference type="SMART" id="SM00028">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="281"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="362"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="770" mass="83058" checksum="9B282431C8C8241E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY19</accession>
    <name>G4MY19_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10452</name>
    </gene>
    <organism evidence="3 4">
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713354.1">
        <property type="nucleotide sequence ID" value="XM_003713306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY19"/>
    <dbReference type="GeneID" id="2682085"/>
    <dbReference type="KEGG" id="mgr:MGG_10452"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10452"/>
    <dbReference type="HOGENOM" id="CLU_1133783_0_0_1"/>
    <dbReference type="InParanoid" id="G4MY19"/>
    <dbReference type="OMA" id="YLAIPIK"/>
    <dbReference type="OrthoDB" id="5245377at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465476" evidence="2">
        <location>
            <begin position="21"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="245" mass="25930" checksum="DD41444ECDE2CACE" modified="2011-12-14" version="1">MQVSLTRVLLAALLAGEAAAAPLPKFGDLFKPDPHGVDVTNPDDPFGFGGKHKRDEAEVASADESAEHGDEVDVADGGDDEPAVEKRDEAESTDADSADAADDEEPAVEKRDEPESADAAAADDDDDEPAVEKRDEPESTDAAAADDDDDEPAVEKRDEPESTDAAAADDDDEEPAVEKRDEPESTDAAAADDDDEEPAVEKRDEPESADAAAADDDDEEPAVEKRDEPESTDEAEVDDEEPTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYW5</accession>
    <name>G4MYW5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">ER membrane protein complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_10831</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMC3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713433.1">
        <property type="nucleotide sequence ID" value="XM_003713385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYW5"/>
    <dbReference type="SMR" id="G4MYW5"/>
    <dbReference type="FunCoup" id="G4MYW5">
        <property type="interactions" value="427"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYW5"/>
    <dbReference type="GeneID" id="2676346"/>
    <dbReference type="KEGG" id="mgr:MGG_10831"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10831"/>
    <dbReference type="eggNOG" id="KOG3188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060791_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYW5"/>
    <dbReference type="OMA" id="KDMDPRW"/>
    <dbReference type="OrthoDB" id="6745403at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008568">
        <property type="entry name" value="EMC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116:SF5">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010045">
        <property type="entry name" value="DUF850_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR010045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA53626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="261" mass="29275" checksum="9C668C551ABB83F6" modified="2011-12-14" version="1">MAAQVPVQTIHRDPQLFYWILGPITVVMILTGMLRHYAAVLMAVAPKKVDAKAMREQRSLLHGINVRSNYHVLSKRSFNTRRDTLSSAYESGAFLKAPESRGQAPPNPMTDPNAMEGMMGMMKNNMAMIVPNTLIMSWINAFFSGYVIMKLPFPLTVKFKSMLQAGVATRDMDPRWMSSISWYFLCIFGLQFVFNFLLGSDNAANQMAQQMGQMGPQAPQMFGPGVDPDKQFLAEAENLAVIEHYSVLDDVEDRLLERLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYX9</accession>
    <name>G4MYX9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_10819</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Required for assembly of cytochrome c oxidase (complex IV).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the COA3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713447.1">
        <property type="nucleotide sequence ID" value="XM_003713399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYX9"/>
    <dbReference type="FunCoup" id="G4MYX9">
        <property type="interactions" value="24"/>
    </dbReference>
    <dbReference type="GeneID" id="2676350"/>
    <dbReference type="KEGG" id="mgr:MGG_10819"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10819"/>
    <dbReference type="eggNOG" id="ENOG502SEY5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153999_2_1_1"/>
    <dbReference type="InParanoid" id="G4MYX9"/>
    <dbReference type="OMA" id="WYTLNAV"/>
    <dbReference type="OrthoDB" id="10018333at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041752">
        <property type="entry name" value="Coa3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018628">
        <property type="entry name" value="Coa3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09813">
        <property type="entry name" value="Coa3_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cytochrome c oxidase assembly factor 3 mitochondrial coiled-coil" evidence="11">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA53640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="81" mass="9060" checksum="0CB3008F7F375666" modified="2011-12-14" version="1">MAGFQGEGYYDRRYRQNPALVRARRPYLVKNAIAGITLAAFTAGVYAYTIHAIGQDEFEDVKVPETPRQPSNIKIQQPSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZJ6</accession>
    <name>G4MZJ6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714362.1">
        <property type="nucleotide sequence ID" value="XM_003714314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZJ6"/>
    <dbReference type="GeneID" id="5048700"/>
    <dbReference type="KEGG" id="mgr:MGG_14779"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14779"/>
    <dbReference type="HOGENOM" id="CLU_2961259_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZJ6"/>
    <dbReference type="OrthoDB" id="10453562at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="59" mass="6745" checksum="1BF95130A6D8FEA7" modified="2011-12-14" version="1">MQASIVSRTGSTLKFTYSRMSSVMTAMEYFLRPRVGGINGLMNFLFILNATRRQFVFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0W2</accession>
    <name>G4N0W2_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA52340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712147.1">
        <property type="nucleotide sequence ID" value="XM_003712099.1"/>
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    <dbReference type="GeneID" id="12984916"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_16782"/>
    <dbReference type="InParanoid" id="G4N0W2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="109" mass="12806" checksum="72DFF0F5A9C5FA3B" modified="2011-12-14" version="1" fragment="single">IMRVIFRGINDLEKLDRVERKEVKQEKRRQLSKILSKILFKLFFPDSNFIWDSSFPINLLNPFLLNKINIFAQYLIGRFFICLFWFVIYINCPISGNIGGMVPGNFGGN</sequence>
</entry>
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    <accession>G4N1B0</accession>
    <name>G4N1B0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_09553</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712188.1">
        <property type="nucleotide sequence ID" value="XM_003712140.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N1B0"/>
    <dbReference type="STRING" id="242507.G4N1B0"/>
    <dbReference type="GeneID" id="2680451"/>
    <dbReference type="KEGG" id="mgr:MGG_09553"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09553"/>
    <dbReference type="eggNOG" id="ENOG502S0GX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001759_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1B0"/>
    <dbReference type="OMA" id="YWREGKC"/>
    <dbReference type="OrthoDB" id="4347at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044389">
        <property type="term" value="F:ubiquitin-like protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050899">
        <property type="entry name" value="DDRGK_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48176">
        <property type="entry name" value="DDRGK DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48176:SF1">
        <property type="entry name" value="DDRGK DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="1542"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="1542"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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            <end position="512"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
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    <feature type="region of interest" description="Disordered" evidence="6">
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            <begin position="1485"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1325"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="75"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="126"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
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            <begin position="134"/>
            <end position="168"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="181"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="262"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="6">
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    <feature type="compositionally biased region" description="Polar residues" evidence="6">
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    <feature type="compositionally biased region" description="Polar residues" evidence="6">
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
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    <feature type="compositionally biased region" description="Low complexity" evidence="6">
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="895"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1494"/>
            <end position="1538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1567" mass="171657" checksum="F3F8AFF07637996C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1D7</accession>
    <name>G4N1D7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Impact family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_09525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712215.1">
        <property type="nucleotide sequence ID" value="XM_003712167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1D7"/>
    <dbReference type="SMR" id="G4N1D7"/>
    <dbReference type="FunCoup" id="G4N1D7">
        <property type="interactions" value="384"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N1D7"/>
    <dbReference type="GeneID" id="2680480"/>
    <dbReference type="KEGG" id="mgr:MGG_09525"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09525"/>
    <dbReference type="eggNOG" id="KOG3299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045276_0_1_1"/>
    <dbReference type="InParanoid" id="G4N1D7"/>
    <dbReference type="OMA" id="HLMQVMD"/>
    <dbReference type="OrthoDB" id="69641at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23822">
        <property type="entry name" value="RWD_ScYIH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="RWD" evidence="8">
        <location>
            <begin position="7"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA52408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="293" mass="31349" checksum="BF0840BF6CF87910" modified="2011-12-14" version="1">MSEELKDEVEALNSIYGDGTLLAASGNDGSDTEAAGAYILKIPGEGETSSLRLQFPAGYPDEPPSVLGTHSSGGQNRPRGAAARDLELFRDALGRVFQPGIVCLFDALEELARLAEELGINDTQPSEADEDGAEEEGTSTAPRKVSAPEDALGPEPPWIMSDVYVEMKSTFVARCAHVTSAAQAESYVAHLLATDKKVRAATHNMTAWRIRGADGKTSFQDCDDDGETAAGGRLLHLMQLMDLWDVMVVVTRWYGGQKLGPRRFAVINQVARDSFVKAGLVPEASGKKKGPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1F0</accession>
    <name>G4N1F0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase OMS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712228.1">
        <property type="nucleotide sequence ID" value="XM_003712180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1F0"/>
    <dbReference type="FunCoup" id="G4N1F0">
        <property type="interactions" value="27"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N1F0"/>
    <dbReference type="GeneID" id="2680522"/>
    <dbReference type="KEGG" id="mgr:MGG_09514"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09514"/>
    <dbReference type="eggNOG" id="KOG4300">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_3_1_1"/>
    <dbReference type="InParanoid" id="G4N1F0"/>
    <dbReference type="OMA" id="WWMGITK"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF83">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="486" mass="53646" checksum="19BDB5E77B3790E7" modified="2011-12-14" version="1">MCAMRQKLPGSLSAVLGRSVALSSGLRTGTGFDFLGYKSGFPPCCRRYIHQSQTNSKKAKSPARSIVVTKTKDLPPALKHRAGKPKSSSNPEEPAKNEKQDKREPLPELFRKYRYPFVGSIVAGSLFMAYASYLITAFVQTSSSAACCGAHPNPDAAAQDDYDETLRQTEPAQPTGLPPTISRATASEFDTGLDWPEWLMGVTKIRQSLAAECRGDVLEVAVGTGRNFKYYDWDDIADVEPNLRVVRRLEKRRDMKLARDQEVEMTSYTGVDVSADVLEIARTRIRTLVPGMKTLLRKGRTKEEEEAGNAQFREAGFEEFLNLQGDKLRLVRADVHNGLPLPPSLSVNSEASGPPPTEEPTRYDVIVQTFGLCSVSSPKRLLANMADVLKPQTGRMLLLEHGRGNWGFVNNVLDKLAPTHFQRFGCWWNRDIERIVRDAASEVPGLEVVSIKRPGVLQAGTTLLIELRVRSDETKDGAAAAVSKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1M6</accession>
    <name>G4N1M6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_13404</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711405.1">
        <property type="nucleotide sequence ID" value="XM_003711357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1M6"/>
    <dbReference type="SMR" id="G4N1M6"/>
    <dbReference type="STRING" id="242507.G4N1M6"/>
    <dbReference type="GeneID" id="2683415"/>
    <dbReference type="KEGG" id="mgr:MGG_13404"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13404"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_1"/>
    <dbReference type="InParanoid" id="G4N1M6"/>
    <dbReference type="OMA" id="IVGMLCT"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000374">
        <property type="entry name" value="3-oxoacyl-(Acyl-carrier-protein) reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF111">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_1G10100)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="389"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA51598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="417" mass="44532" checksum="5573CD9DCCFED13F" modified="2011-12-14" version="1">MAGILKGKLALVTGSSRGIGAAIAANLAAKGSDVILNYTSSSSQSITKELSDSLTSQHGIKTYIVQADLGTPGGPAELIKLTKEQFASTNSDRPFQIDIIVNNAGIALNDKLPDLTTEQFEKTYRVNVLGPLLLMQAAEPYLPTDRSGRVVNLSSVSSATGFVGQSVYGGTKAALEAMTRTWARELSERCTVNAVNPGPVLGPMYASNTDEFKAQIKGWIDHTPLMRPREGIDAQELVEDAKTSGGRPAYPSEVAGIVGMLCTPDAAWCTGQVVCANGGMILSCKRDYGKKPENIPGKVIEAYSPVNECQSNGIQHSKIYHQIRDINENDTRIGSMRLSLGNVAQQQTEPVMVIVRVSISAGKMDMRLQHFLILIRHLAPLRNLSGSTGPEEDIGRYPLTSPAAHGVITTPSTPSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N212</accession>
    <name>G4N212_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713129.1">
        <property type="nucleotide sequence ID" value="XM_003713081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N212"/>
    <dbReference type="SMR" id="G4N212"/>
    <dbReference type="GeneID" id="2683813"/>
    <dbReference type="KEGG" id="mgr:MGG_07886"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07886"/>
    <dbReference type="HOGENOM" id="CLU_2373195_0_0_1"/>
    <dbReference type="InParanoid" id="G4N212"/>
    <dbReference type="OMA" id="ECYQIYL"/>
    <dbReference type="OrthoDB" id="5238058at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="95" mass="10736" checksum="BBDFF268E084F6F7" modified="2011-12-14" version="1">MSNQESQPEPFRGDPPSTDDLLENLEQCQAKIDECYQIYLHNEKKKSAELEKKLAEALKMIKKLEALKIVMEHNHEQAITPQSTPAESTAGNICP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2Z9</accession>
    <name>G4N2Z9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CAMK protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_16669</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711565.1">
        <property type="nucleotide sequence ID" value="XM_003711517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2Z9"/>
    <dbReference type="SMR" id="G4N2Z9"/>
    <dbReference type="STRING" id="242507.G4N2Z9"/>
    <dbReference type="GeneID" id="12984136"/>
    <dbReference type="KEGG" id="mgr:MGG_16669"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16669"/>
    <dbReference type="eggNOG" id="KOG0615">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013541_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2Z9"/>
    <dbReference type="OMA" id="RDIMITA"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="120"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA51758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="775" mass="85313" checksum="C2C93229C53FA1B6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G4N388</accession>
    <name>G4N388_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Arginase</fullName>
            <ecNumber evidence="2 11">3.5.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_10854</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>L-arginine + H2O = urea + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:20569"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="EC" id="3.5.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="11">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.1" evidence="2 11"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713240.1">
        <property type="nucleotide sequence ID" value="XM_003713192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N388"/>
    <dbReference type="SMR" id="G4N388"/>
    <dbReference type="FunCoup" id="G4N388">
        <property type="interactions" value="1313"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N388"/>
    <dbReference type="GeneID" id="2676370"/>
    <dbReference type="KEGG" id="mgr:MGG_10854"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10854"/>
    <dbReference type="eggNOG" id="KOG2965">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039478_6_1_1"/>
    <dbReference type="InParanoid" id="G4N388"/>
    <dbReference type="OMA" id="FSWMTPC"/>
    <dbReference type="OrthoDB" id="9992747at2759"/>
    <dbReference type="UniPathway" id="UPA00158">
        <property type="reaction ID" value="UER00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09989">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000009">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014033">
        <property type="entry name" value="Arginase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01229">
        <property type="entry name" value="rocF_arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782:SF3">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA53433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="357" mass="38476" checksum="EBEA48478F5B6ABE" modified="2011-12-14" version="1">MSSTHATQNGSNSQTDASTPDYTKTPPVMLTTMVESKFLSSPEDLGVVAVGFSGGQCKPGVDAAPSALIDSGLLTQLHSELGYRLHGHTQVHLYGDLEPANDPPYRNMKKPLAVSAVTRRIAEQTYEQAKEGRMVLTLGGDHSIAIGTIGGVAKAIKERFQGRREVAVIWVDAHADINTPETSDSGNIHGMPVSFLTGLATEDKDEYFGWLKDDNRISVNKLVYIGLRDVDPGEKKILRENKIKAFSMFDIDRHGIGRVMEMALAHIGTDTPIHLSFDVDALDPMWAPSTGTPVRGGLTLREGDYICECVHETGQLVAMDLVEVNPSLSPSDGDPGAHETVRAGCSLVRCALGESLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4G9</accession>
    <name>G4N4G9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712644.1">
        <property type="nucleotide sequence ID" value="XM_003712596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4G9"/>
    <dbReference type="GeneID" id="12985143"/>
    <dbReference type="KEGG" id="mgr:MGG_16873"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16873"/>
    <dbReference type="HOGENOM" id="CLU_1855659_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4G9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="138" mass="15635" checksum="9A75D4C1A5817A7B" modified="2011-12-14" version="1">MVGAQRRKGPWPVISIGAAQLFRHEPLYCHKASPRIFPQICVLTVLRTSSPLNPAQLSQQRKAPNAARIPSSLHNTTQTRGPYTVLWLHPRPAPQIFFNQDQRKLPPEPRGKLQMLQLILTTYQLGKVRNSAAPRIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4X2</accession>
    <name>G4N4X2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711891.1">
        <property type="nucleotide sequence ID" value="XM_003711843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4X2"/>
    <dbReference type="GeneID" id="12984241"/>
    <dbReference type="KEGG" id="mgr:MGG_16745"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16745"/>
    <dbReference type="HOGENOM" id="CLU_2923098_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4X2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="61" mass="6519" checksum="BAC72B8D0FC92BC1" modified="2011-12-14" version="1">MSAVEDQGRYRGGLYQLTGLVPFVGSCVVLGVGVVPESEKLDLGYVSVDPCTRRLPTDFTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N524</accession>
    <name>G4N524_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712742.1">
        <property type="nucleotide sequence ID" value="XM_003712694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N524"/>
    <dbReference type="GeneID" id="12985179"/>
    <dbReference type="KEGG" id="mgr:MGG_16882"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16882"/>
    <dbReference type="HOGENOM" id="CLU_2923100_0_0_1"/>
    <dbReference type="InParanoid" id="G4N524"/>
    <dbReference type="OrthoDB" id="10369259at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="61" mass="7200" checksum="55346CE511DED945" modified="2011-12-14" version="1">MESRRNLQRVIKVTFNGMRSRQLFLAERTGEADVKEGPKKKQQQQQQQTAYGRRSFLCDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N630</accession>
    <name>G4N630_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716925.1">
        <property type="nucleotide sequence ID" value="XM_003716877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N630"/>
    <dbReference type="GeneID" id="12985484"/>
    <dbReference type="KEGG" id="mgr:MGG_14864"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14864"/>
    <dbReference type="HOGENOM" id="CLU_2373196_0_0_1"/>
    <dbReference type="InParanoid" id="G4N630"/>
    <dbReference type="OrthoDB" id="10303229at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="95" mass="10972" checksum="D52121AE305C6BB0" modified="2011-12-14" version="1">MCYGWYEYFKCMQCSSTYGSRYNVRKCALEKSTRFCSQSGPRGKLMVAEIEDDVKMDWACEKCKRNDKGDVAGQTNSGVKPLVWNDQNNAWSTTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6H7</accession>
    <name>G4N6H7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716166.1">
        <property type="nucleotide sequence ID" value="XM_003716118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6H7"/>
    <dbReference type="GeneID" id="2676542"/>
    <dbReference type="KEGG" id="mgr:MGG_03715"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03715"/>
    <dbReference type="eggNOG" id="ENOG502RNF4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1240354_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6H7"/>
    <dbReference type="OMA" id="PHTRIKS"/>
    <dbReference type="OrthoDB" id="4747243at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465805" evidence="2">
        <location>
            <begin position="19"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="207" mass="22198" checksum="4F1B7F288C8B87DC" modified="2011-12-14" version="1">MKSTTLLPFLCVLAAALPATINHNREPDAHHFAPVTRIHPSTIEQDLEAPIDNRPQNPSTSDIPSVILASQKPIQSTYLLGLPRAGNDEDEPATKPAALGSEPLGDSSDGHETQTQAQKPTQAHAAHPCVSRQHVDIAVICFVALFLLAVVAVESKESIWSYRTAHDVADGAIRLDTEAAVSAKQLSVQAWAYSDGDDNSEAEKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6J6</accession>
    <name>G4N6J6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_14859</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716984.1">
        <property type="nucleotide sequence ID" value="XM_003716936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6J6"/>
    <dbReference type="SMR" id="G4N6J6"/>
    <dbReference type="GeneID" id="5049197"/>
    <dbReference type="KEGG" id="mgr:MGG_14859"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14859"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_2_1_1"/>
    <dbReference type="InParanoid" id="G4N6J6"/>
    <dbReference type="OMA" id="WCAHEIL"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11065">
        <property type="entry name" value="CYP64-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF4">
        <property type="entry name" value="CYTOCHROME P450 98A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="65383" checksum="C7D51F020C74B91F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7D3</accession>
    <name>G4N7D3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003716263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7D3"/>
    <dbReference type="GeneID" id="12984400"/>
    <dbReference type="KEGG" id="mgr:MGG_17068"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17068"/>
    <dbReference type="HOGENOM" id="CLU_2483789_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7D3"/>
    <dbReference type="OrthoDB" id="10401954at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="87" mass="9893" checksum="50E16CDFB120816D" modified="2011-12-14" version="1">MHVPFFSEPCQSQVKHTHPNWPMMPENSQRFGNMMHAVAYPAVRLTNVERQVSRLHLFCQGKPVVSELPAYGRAVVSSYNMGSIHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7E5</accession>
    <name>G4N7E5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716323.1">
        <property type="nucleotide sequence ID" value="XM_003716275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7E5"/>
    <dbReference type="GeneID" id="2677002"/>
    <dbReference type="KEGG" id="mgr:MGG_03586"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03586"/>
    <dbReference type="eggNOG" id="ENOG502S8NQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_542984_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7E5"/>
    <dbReference type="OMA" id="SRDDHEP"/>
    <dbReference type="OrthoDB" id="10249419at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="502" mass="55080" checksum="4931C6932FBCC021" modified="2011-12-14" version="1">MEVVYVQPQDYSAYHSGDTIRTTQSTEDEVNRIMDWNYGLAKTDAPRSVYSGGGTRTTLTHRPRYVDMADDPILLRRSVTTSTIIEGSPFASSSGSPPKADSSISASSAGMYGLLGAAVGAAAGAAMTYGMMTKDRSQAPRQEFGSDSGPVPSVQRRSTFPEQKVNFTTAPQYHHPPPPMPGQRYVELERTVEKIRYPEDFATNGHYPHPPAYMARYSQAGGPSSKKGDVFDDSKSRYSSSSKYRGDRLIREPPAVGQVPLLLTEAEHRSHVGSSISRHSTVKPPPSEQRSYVGSKYAPSTKPPPAAPNPPPPMSTTRRSAYESATDRDTYVSARSHRSTSTLRADPVSRPEPEVYGSYPPPAGSSRGPRAASRAKSSSTIRGRDRDLNETPKDRSHSRASTKFERQFPMPNNPVARHYPLPPSHDGRSLYSEVPPPKKSHRSSSGRKSHHRDSQPLTRSALDDNDRATWEEWDEDDDDAVSLAPSDSISCVGSKKSSRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7N8</accession>
    <name>G4N7N8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Solute carrier family 25 member 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_03553</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716362.1">
        <property type="nucleotide sequence ID" value="XM_003716314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7N8"/>
    <dbReference type="SMR" id="G4N7N8"/>
    <dbReference type="GeneID" id="2676428"/>
    <dbReference type="KEGG" id="mgr:MGG_03553"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03553"/>
    <dbReference type="eggNOG" id="KOG0763">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_16_1_1"/>
    <dbReference type="InParanoid" id="G4N7N8"/>
    <dbReference type="OMA" id="WVTATPF"/>
    <dbReference type="OrthoDB" id="193856at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF10">
        <property type="entry name" value="SLC (SOLUTE CARRIER) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="2"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="125"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA50043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="32427" checksum="A293D195839E9C3D" modified="2011-12-14" version="1">MSADFWAGYISGAAGILIGNPLDVVKVRLQAAQPNTASSASPILSPVSPLPSHTANTPHQDAAASRSFSRIRALAAGTAAPVLGYGALNALLFVSYNRTESLLNSALAGSNAASTAAGGGSTTGSNLWTTWIAGAVGGLATWVVSTPTELVKCRAQLALSSSPSSLQAGTTSTSSWAVAKHAWRTEGGIRAFYFGGGVTALRDSIGYGFYFWTYELCSHWMESRRERAGSGGSGGIVDDFMGSEAARVLLAGGLAGVVTWASVFPLDTIKTRVQAQQINANSGPRTATAQGLARVGLTKEWLRKRRSSGGWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8L7</accession>
    <name>G4N8L7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Riboflavin transporter MCH5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_03411</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716530.1">
        <property type="nucleotide sequence ID" value="XM_003716482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8L7"/>
    <dbReference type="SMR" id="G4N8L7"/>
    <dbReference type="GeneID" id="2676570"/>
    <dbReference type="KEGG" id="mgr:MGG_03411"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03411"/>
    <dbReference type="eggNOG" id="KOG2504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_1_1_1"/>
    <dbReference type="InParanoid" id="G4N8L7"/>
    <dbReference type="OMA" id="LFMWGMF"/>
    <dbReference type="OrthoDB" id="5667at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF224">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="87"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA50211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="480" mass="51080" checksum="4C9223312EA0FBDD" modified="2011-12-14" version="1">MSGEKLQPIFDHDKGMDTSSSSAVLSQHTNPSSTSIKETMESSKANGDAEKGNISDSDNAPIPSGPPAGPAPGSGFHPSDFPDGGLEAWLVVFGGFCALFCTFGLVNCIGVFQTYYVQGPLASYGQSTVSWITAMQVFGMVFGGIVFGRLYDSYGPRWLIIGGTLVYVFGLMMVSLCTEYYQFFLAQGIVSAIGSSAIFNSVLPTLVGWFFKRRAAAFGITAAGSSLGGVVLPIMMNKLIPQIGFGWTIRIVAFIFLALLGISVVTVKSRLPPRPKPFVLAEYTDAFKDPVYALTLVANFLFFWGMFLPFNFIILQAIKAGMDPKLAEYLLPIINAVSIFGRILPGIAADRFGRYNMMILITGLSALFTLALWIPGTSTGAIIGFAIVFGFVSGGFIGMAPTLIAQISDIRQIGVKTGLAFAVQSFGALTGSPIAGAIVNSQGGQYIGLQLFCGLTMAASVVFYLAARSKYGGVKLMQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8V0</accession>
    <name>G4N8V0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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                <person name="Mitchell T.K."/>
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                <person name="Kulkarni R."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
        </source>
    </reference>
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        <cofactor evidence="1">
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    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Jeong J.S."/>
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                <person name="Djonovic S."/>
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                <person name="Bohnert H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA49581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="SGF29_tudor-like_dom"/>
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        <property type="entry name" value="Tudor_SGF29_rpt1"/>
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        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539:SF0">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SGF29_Tudor"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SGF29_C"/>
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    <proteinExistence type="predicted"/>
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            <begin position="249"/>
            <end position="389"/>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="106"/>
            <end position="244"/>
        </location>
    </feature>
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            <begin position="294"/>
            <end position="315"/>
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    </feature>
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            <begin position="1"/>
            <end position="17"/>
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            <begin position="110"/>
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            <begin position="230"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="389" mass="42020" checksum="C0B9B2CE0B6A08CB" modified="2011-12-14" version="1">MASQRNNRPARGSSRNDSAAEEVQLWEQIQGELRQIVDQFNASTEIGRKIKTQDQILKENPGRTTMDATFNQLEELLRSGVKTNDDLVEKIRAVRTNIEILSALSKAKDPSGSSGGKSSQHLNPSSARSSGLGGSSRNASRGATATREAHRSKDKEAKEAKEAKEASSQKDQSSLYDFDGAESPVPSPHGNHTVRKLGSERSAGRDSLPPRGDRDTPSKADSAEPPQLPATGSSVGSSTSASAAALQRSKVVFAKGQDVAFKPKQANNSSNNGDTADWFLGRVAAVLGEGKSRRYKVKDEDPDVSPDERKEYRTSASSMIPIPAAGEKLPSLDKGKIVLALYPDSTTFYKAEVESIDAETGKVSLRFEGEETTGTLQLVERRFVVEYRP</sequence>
</entry>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716713.1">
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_03259"/>
    <dbReference type="HOGENOM" id="CLU_2097339_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9U2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="116" mass="13245" checksum="8ACC12BB7685E553" modified="2011-12-14" version="1">MENRHHFKPPLIFLTKTATEGEEDKNNPAEGTPGALTKVTIADRTYQSATSKTTFQLRVSRDVWDIISELEPQVPKKPIMYSTDFVNVYQEIKQHYEDTLPNTELKARAFSTSSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9W3</accession>
    <name>G4N9W3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003716686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9W3"/>
    <dbReference type="GeneID" id="12985398"/>
    <dbReference type="KEGG" id="mgr:MGG_17127"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17127"/>
    <dbReference type="HOGENOM" id="CLU_2688293_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9W3"/>
    <dbReference type="OrthoDB" id="10431237at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="74" mass="7946" checksum="1ABC5C63CC92B5EF" modified="2011-12-14" version="1">MAIGSDGDGGGWLFAAPSNRELNEVLPTRRPSVEWRQVRCATKPQSTTTESPSTSVYSRKSGAVSTGSLLRHVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA26</accession>
    <name>G4NA26_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717591.1">
        <property type="nucleotide sequence ID" value="XM_003717543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA26"/>
    <dbReference type="GeneID" id="2680758"/>
    <dbReference type="KEGG" id="mgr:MGG_09759"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09759"/>
    <dbReference type="HOGENOM" id="CLU_1960009_0_0_1"/>
    <dbReference type="InParanoid" id="G4NA26"/>
    <dbReference type="OMA" id="PRGCDNQ"/>
    <dbReference type="OrthoDB" id="5240306at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="128" mass="14188" checksum="8F1F452B41337284" modified="2011-12-14" version="1">MELKYKNEVLYSVNRYFPFTKRQRRGKFCPRGCDNQSQSNANQAGQSSGSNSKPGSSSHQSSYSYGSTATYAQQNSGSEPFNTQSPHVQGNQGNIAAAEKRHQQNAERSIGAFESQFNGQNQGQNRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA63</accession>
    <name>G4NA63_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Intradiol ring-cleavage dioxygenases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715932.1">
        <property type="nucleotide sequence ID" value="XM_003715884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA63"/>
    <dbReference type="SMR" id="G4NA63"/>
    <dbReference type="GeneID" id="2678691"/>
    <dbReference type="KEGG" id="mgr:MGG_08431"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08431"/>
    <dbReference type="eggNOG" id="ENOG502QPRK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027719_0_1_1"/>
    <dbReference type="InParanoid" id="G4NA63"/>
    <dbReference type="OMA" id="MDGQFID"/>
    <dbReference type="OrthoDB" id="121380at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF1">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466352" description="Intradiol ring-cleavage dioxygenases domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="2">
        <location>
            <begin position="113"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="347" mass="37503" checksum="4DA10DE80D1A368F" modified="2011-12-14" version="1">MLDRLAINLLLLASSAAVLAHPGADVRTEFLERQEHLNNPARRTLSECHARLEARGHYAAELERRMTKINGLRSKRGLQAAPGAVQKRDGGARAGCVLDPEVTEGPFWVQGEVIRPDIREDSNGVVLHLDINVIDVTTCEPIPDAYVELWGCNSTGVYTGVIAKGNGVGLDAPEEINNSALRGVQPTDADGTASFVTIVPGHYVGRTNHLHTIVHHGATRLSNDTIQGGTVSHVGQFYFDDVSIEAVELESPYSTNTQAWTRNADDFLLRQGQAGGDNPFIELTLLGGSMADGLHGVIDVGVDPSAKQEPKPVNFWTADGGKPVEGSPWAGYPWTVRLMALLRRWGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA85</accession>
    <name>G4NA85_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Elicitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08454</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Necrosis inducing protein (NPP1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715954.1">
        <property type="nucleotide sequence ID" value="XM_003715906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA85"/>
    <dbReference type="SMR" id="G4NA85"/>
    <dbReference type="STRING" id="242507.G4NA85"/>
    <dbReference type="GeneID" id="2678752"/>
    <dbReference type="KEGG" id="mgr:MGG_08454"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08454"/>
    <dbReference type="eggNOG" id="ENOG502S1MP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062263_1_0_1"/>
    <dbReference type="InParanoid" id="G4NA85"/>
    <dbReference type="OMA" id="AHGGWDC"/>
    <dbReference type="OrthoDB" id="89086at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF8">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466247" evidence="3">
        <location>
            <begin position="19"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="235" mass="25307" checksum="799457B1E371B71A" modified="2011-12-14" version="1">MLPKFFTLLATAVSAVAAGPLAARDVINHDAVVGFPQSVPNSNAGRNMLRFKPWLKVFSGCVPFPAVDQWGNTGGGLKTSGSHSSGCSKNVGQVYARAGTQAGRGAIMYSWYMPKDSPSPGMGHRHDWENVIIWLDDVNSANARIIGASASGHGGYDTRDSIARDGDRALIRYFSNWPLNHQMGFTGERGGEQPLVSWDTMTQAARNALEWTDFGAAGVPFKDGSFQNNLAKVFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAL6</accession>
    <name>G4NAL6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715978.1">
        <property type="nucleotide sequence ID" value="XM_003715930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAL6"/>
    <dbReference type="GeneID" id="12986846"/>
    <dbReference type="KEGG" id="mgr:MGG_17021"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17021"/>
    <dbReference type="HOGENOM" id="CLU_2146361_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAL6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="112" mass="12478" checksum="CE59EDBEE7873269" modified="2011-12-14" version="1">MDRDYHFYKKERLFCQKVIIQYVLDLDIRGLPPWIANVAATADNILGQALQVARADQEEAGHGHPSQRPNGAHLLLSRLTFGASPQDLIQNRRPTLPLTPPGSLKQSNSRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAM6</accession>
    <name>G4NAM6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715988.1">
        <property type="nucleotide sequence ID" value="XM_003715940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAM6"/>
    <dbReference type="SMR" id="G4NAM6"/>
    <dbReference type="STRING" id="242507.G4NAM6"/>
    <dbReference type="ESTHER" id="maggr-a4qy60">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="GeneID" id="2678782"/>
    <dbReference type="KEGG" id="mgr:MGG_08480"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08480"/>
    <dbReference type="eggNOG" id="KOG2984">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_47_0_1"/>
    <dbReference type="InParanoid" id="G4NAM6"/>
    <dbReference type="OMA" id="HGRSTFK"/>
    <dbReference type="OrthoDB" id="190201at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466266" evidence="1">
        <location>
            <begin position="20"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="67"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="291" mass="31327" checksum="E40F1A7D0053323F" modified="2011-12-14" version="1">MVSFTTLLLAAAASLSTEARNVPRDSPVWLTLPPTPQLPSPISNKLYPINGVNLWLQKYNEAKGGVPIVVSHGGLGSSEYFGAVIQELIKRGYYVVASDRRGHGRSTFNANDVFTYDMFAQDQDALLKAVGINKYIFVGWSDGAIQGLSALMDPKLAAPMQKAFLFGTTASPADTNVNFPKTAIFNDFVTRVATEYPTLQPKADFKAFAGKVSTLESTLPNFTAADFAKIDGTKVTMVEADHEEAVNKGTGLRISKQIPGSKFVSLQGGSHFSPVQIPAKFADAIEAFLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBK9</accession>
    <name>G4NBK9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717698.1">
        <property type="nucleotide sequence ID" value="XM_003717650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBK9"/>
    <dbReference type="GeneID" id="2676295"/>
    <dbReference type="KEGG" id="mgr:MGG_10760"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10760"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_763072_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBK9"/>
    <dbReference type="OMA" id="ADSHEGR"/>
    <dbReference type="OrthoDB" id="4494341at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:ferric-chelate reductase activity"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF26">
        <property type="entry name" value="FAD-BINDING 8 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding 8" evidence="3">
        <location>
            <begin position="154"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="415" mass="46553" checksum="CBAB8DD10D691422" modified="2011-12-14" version="1">MDLALQRYALCIGGLLLLLLTSRFIYRYRGHLHPLQTAFRLQFLYRNIGRLPIPIAVWSVCFLAANIFILFKSPTLRSVRAGYLVIFNIQPLLLAVHSDVLIDLLGASRQSYFFFHRAAAWTTAVLTAFHSIGMVLNGRSFSFRSIGNILAFSYINLTVPSLDASSSIQSHPFVVTSWSKDRQKSLDLFVERRRGFTRKLHLADSHEGRHAIVSGPFGRRVSLLEFDFVLLLASGYGIAAQAAYLRELVSGGNRQKAHLVWLISKRDIVNPAGKWLLNPVLDQDTKKARSILILVRTQLTGPQMILISIFDNVGSLEGTPSAADSTVAKTFGGRARLYKGKPDLKAIIRKGMQDCLCEERSRNGRLLLLEARLHVKRALRSYLRELKAGSDPRTSYGSCNHSIDVSIEELDFQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBN4</accession>
    <name>G4NBN4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ecp2 effector protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_10781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717723.1">
        <property type="nucleotide sequence ID" value="XM_003717675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBN4"/>
    <dbReference type="GeneID" id="2676299"/>
    <dbReference type="KEGG" id="mgr:MGG_10781"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10781"/>
    <dbReference type="eggNOG" id="ENOG502STIA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1489076_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBN4"/>
    <dbReference type="OMA" id="RYEASYF"/>
    <dbReference type="OrthoDB" id="3768082at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466072" description="Ecp2 effector protein domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="195" mass="21335" checksum="71FF383B39679D54" modified="2011-12-14" version="1">MRFFTTLPFMATAVLGLATGLVDRADLPDGGYVFNHYDNGTVTALPLDTPGAEEILIKPIVPKAEPEAEHGIQKRWVTCSPGNTLDPAGVDEGVRQLQSFHATNSKNWAGPGGRYLSSGDRNAVIRFISRGMMVYYCIDTKWWTGNLDIADIDYALRNMDSVCRRYTASHFQWDSPEIVGKADVNLAVCCGGGNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCZ4</accession>
    <name>G4NCZ4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718768.1">
        <property type="nucleotide sequence ID" value="XM_003718720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCZ4"/>
    <dbReference type="GeneID" id="12984983"/>
    <dbReference type="KEGG" id="mgr:MGG_17478"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17478"/>
    <dbReference type="HOGENOM" id="CLU_3069187_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCZ4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466820" evidence="2">
        <location>
            <begin position="19"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="53" mass="5596" checksum="209FA221ABA58108" modified="2011-12-14" version="1">MKFSAIFAILTLASAAAAAPAESSTHQDANNIIIRNDVNDGPYDENNKAYNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDG1</accession>
    <name>G4NDG1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718034.1">
        <property type="nucleotide sequence ID" value="XM_003717986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDG1"/>
    <dbReference type="GeneID" id="5050629"/>
    <dbReference type="KEGG" id="mgr:MGG_11469"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11469"/>
    <dbReference type="eggNOG" id="ENOG502S56A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096870_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDG1"/>
    <dbReference type="OMA" id="FYWVLDT"/>
    <dbReference type="OrthoDB" id="63581at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037970">
        <property type="entry name" value="vanZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="221" mass="23973" checksum="F7B19BE27E75346A" modified="2011-12-14" version="1">MRIRLPFAGVFFFLLLIAGYAGLTSLQLGELINDKLLHLITFFALTVVFYWIVDTNRRRTLNLTLTVCTFSLGVGSEFLQALLPNGRDFDVYDIAANLVGSLAGLALCSWYHKRMRKGYQPVDGVDGDPGEEDVELGEGLGYSNDGGHEEGITDAPVYTEPSGPVGDRGLTLEEEVDNWDENGEDAWDEADVGDIGDATPAAKSQGIDAENGDGKPPKRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDQ1</accession>
    <name>G4NDQ1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP synthase subunit 9, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_00892</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the ATPase C chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718073.1">
        <property type="nucleotide sequence ID" value="XM_003718025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDQ1"/>
    <dbReference type="SMR" id="G4NDQ1"/>
    <dbReference type="FunCoup" id="G4NDQ1">
        <property type="interactions" value="741"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NDQ1"/>
    <dbReference type="GeneID" id="2674459"/>
    <dbReference type="KEGG" id="mgr:MGG_00892"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00892"/>
    <dbReference type="eggNOG" id="KOG3025">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116822_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDQ1"/>
    <dbReference type="OMA" id="MKRQTIQ"/>
    <dbReference type="OrthoDB" id="438052at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033177">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, proton-transporting domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18182">
        <property type="entry name" value="ATP-synt_Fo_c_ATP5G3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.20.10:FF:000006">
        <property type="entry name" value="ATP synthase subunit 9, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031">
        <property type="entry name" value="ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031:SF13">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0138">CF(0)</keyword>
    <keyword evidence="9 17" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="12 17" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13 17" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 17" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="18">
        <location>
            <begin position="79"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA48489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="144" mass="15215" checksum="4F9C9FE091A5DDFF" modified="2011-12-14" version="1">MASTRVLASRLANTMAQTATKAARPAFRTQARTFTGMTLKRQSAPSMMAATISRQAFQTQRRAYSSEIAQAMVEVSKNIGMGSAAIGLTGAGIGIGLVFAALLNSVARNPALRGQLFSYAILGFAFVEAIGLFDLMVALMAKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE63</accession>
    <name>G4NE63_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00151</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR6 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA49392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003718928.1"/>
    </dbReference>
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    <dbReference type="FunCoup" id="G4NE63">
        <property type="interactions" value="587"/>
    </dbReference>
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    <dbReference type="GeneID" id="2675220"/>
    <dbReference type="KEGG" id="mgr:MGG_00151"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00151"/>
    <dbReference type="eggNOG" id="KOG0974">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002615_1_1_1"/>
    <dbReference type="InParanoid" id="G4NE63"/>
    <dbReference type="OMA" id="IIVWSCF"/>
    <dbReference type="OrthoDB" id="5594999at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051973">
        <property type="entry name" value="tRNA_Anticodon_Mtase-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
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    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="240"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
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            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00038255"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1261" mass="134601" checksum="D391C58421B4932C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NED4</accession>
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    <organism evidence="2 3">
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718201.1">
        <property type="nucleotide sequence ID" value="XM_003718153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NED4"/>
    <dbReference type="FunCoup" id="G4NED4">
        <property type="interactions" value="5"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NED4"/>
    <dbReference type="GeneID" id="2674418"/>
    <dbReference type="KEGG" id="mgr:MGG_00788"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00788"/>
    <dbReference type="eggNOG" id="ENOG502SBHE">
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    <dbReference type="HOGENOM" id="CLU_136313_0_0_1"/>
    <dbReference type="InParanoid" id="G4NED4"/>
    <dbReference type="OMA" id="VEVRWTN"/>
    <dbReference type="OrthoDB" id="5555533at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    <dbReference type="PANTHER" id="PTHR28230">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR28230:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19117">
        <property type="entry name" value="Mim2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="110" mass="12508" checksum="6D298172285C6851" modified="2011-12-14" version="1">MSAPTGSYILPEHAAPSDDHDDLDSLPSISTSLLDSEPDSEAQREWEESLEQLQLMLTMVIIPFTGKYMGRKFAFWSWARYMEWMHNVEIRWTNKKAFVAAGVIEAAATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NES4</accession>
    <name>G4NES4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_11680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CbxX/CfxQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719081.1">
        <property type="nucleotide sequence ID" value="XM_003719033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NES4"/>
    <dbReference type="SMR" id="G4NES4"/>
    <dbReference type="STRING" id="242507.G4NES4"/>
    <dbReference type="GeneID" id="5050843"/>
    <dbReference type="KEGG" id="mgr:MGG_11680"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11680"/>
    <dbReference type="eggNOG" id="KOG0730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_392351_0_0_1"/>
    <dbReference type="InParanoid" id="G4NES4"/>
    <dbReference type="OMA" id="CERIVAM"/>
    <dbReference type="OrthoDB" id="2423195at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000216">
        <property type="entry name" value="Type VII secretion ATPase EccA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000160">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041627">
        <property type="entry name" value="AAA_lid_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050773">
        <property type="entry name" value="CbxX/CfxQ_RuBisCO_ESX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN / ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392:SF2">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN _ ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17866">
        <property type="entry name" value="AAA_lid_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
        <property type="entry name" value="CBXCFQXSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="412"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="641"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="273"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="657"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA49497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="703" mass="77632" checksum="1DDB4160D20E3030" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEZ8</accession>
    <name>G4NEZ8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718308.1">
        <property type="nucleotide sequence ID" value="XM_003718260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEZ8"/>
    <dbReference type="SMR" id="G4NEZ8"/>
    <dbReference type="FunCoup" id="G4NEZ8">
        <property type="interactions" value="673"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NEZ8"/>
    <dbReference type="MEROPS" id="C85.008"/>
    <dbReference type="GeneID" id="2674866"/>
    <dbReference type="KEGG" id="mgr:MGG_11505"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11505"/>
    <dbReference type="eggNOG" id="KOG2606">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034963_2_0_1"/>
    <dbReference type="InParanoid" id="G4NEZ8"/>
    <dbReference type="OMA" id="YELGAHY"/>
    <dbReference type="OrthoDB" id="415023at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22762">
        <property type="entry name" value="OTU_fungi_OTU2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049771">
        <property type="entry name" value="OTU2-like_OTU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF10">
        <property type="entry name" value="DEUBIQUITINASE OTUD6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="160"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="304" mass="34037" checksum="D9A7BBD24D0A51CF" modified="2011-12-14" version="1">MESLEQMQARHRKELKDLQGRITSKKKNATKKTRKGVNDECAELERQMKERHESETRQLGGTAEEEEAEKSEDEPAVDDTRQNGESQAPSNEKESVEVGGTQPPQNQAGKKRNRQKERLARRAAEQEAAAEAAAAEASNMVDHRSNEAAHMARELATHSLVEKEIAPDGHCLFSAFADQLSTLSIPLQQKSGAGDDSVPAYRIVRRAASSYISDHADDFAPFLEEPLDDYVRKMRDTAEWGGHMELLALASTYNVEVRVIADGRTAVVQPKEPKEDEPARQVWLAYYRHGFGLGEHYNSLRKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF04</accession>
    <name>G4NF04_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinetoplast-associated protein KAP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Pearson M."/>
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                <person name="Shea T."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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                <person name="Nicol R."/>
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            <dbReference type="PubMed" id="15846337"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
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                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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    </evidence>
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</entry>
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    <accession>G4NG14</accession>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Young S.K."/>
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                <person name="Fitzgerald M."/>
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                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
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                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF147">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA46971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="536" mass="59534" checksum="B07FD297705ACC6A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG40</accession>
    <name>G4NG40_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ketoreductase (KR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719364.1">
        <property type="nucleotide sequence ID" value="XM_003719316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG40"/>
    <dbReference type="GeneID" id="2676394"/>
    <dbReference type="KEGG" id="mgr:MGG_14288"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14288"/>
    <dbReference type="eggNOG" id="ENOG502T21R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1235246_0_0_1"/>
    <dbReference type="InParanoid" id="G4NG40"/>
    <dbReference type="OMA" id="TIHISRM"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase (KR)" evidence="1">
        <location>
            <begin position="96"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="224" mass="24049" checksum="26C7A59B2826823F" modified="2011-12-14" version="1">MVQGLVCTVSMEDRALDITLLEAVLGVSASGIAFGIQNVAESLADCRKGGSTGLDADKDYSIQGDGTIHISRMKWVPLPEQIVDTSRGAKFRDDAPYLLGGGMEGLGGAVATWIAEQGPRHFVFLLRSVADPRNEPFVQELRSYPGGSVITISGDVGYVVDSEQAHQFFWRNLNLLWALILNFFVFGSSAKVKGMNQLLIPSAVAQSSRAVGLVSGFALHIIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH37</accession>
    <name>G4NH37_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alkyl transferase</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_12110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719914.1">
        <property type="nucleotide sequence ID" value="XM_003719866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH37"/>
    <dbReference type="SMR" id="G4NH37"/>
    <dbReference type="FunCoup" id="G4NH37">
        <property type="interactions" value="411"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NH37"/>
    <dbReference type="GeneID" id="2677333"/>
    <dbReference type="KEGG" id="mgr:MGG_12110"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12110"/>
    <dbReference type="eggNOG" id="KOG1602">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038505_0_2_1"/>
    <dbReference type="InParanoid" id="G4NH37"/>
    <dbReference type="OMA" id="FDRRDLW"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016094">
        <property type="term" value="P:polyprenol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="214"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA47547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="351" mass="40314" checksum="EBCC924C654B1E3F" modified="2011-12-14" version="1">MSDLHMSHITKWFTSSPPAEWAIKNLRQLLIGALRQGPIPRHVAFEMDGNRRYARSHKIETVAGHHMGFEALARVLEICYNCGVKVVTVYAFSIENFNRPKYEVEGLMQMAKYKLEQLLEHGEVLDRYGARVIISGQRDLIPPDVLGFVDRAVNETKHNKGHILNICFPYTSREEITQAIRSTAVEYSSHPRPQNSAFSQTRIKQKILSKHAGNKEAALGSIQESPPPDDVDCSVSSGTTLPPGTPPSSDSTTQDVPRAFKNPETITAETLNNHMYTAECPPLDLFIRTSGVERLSDFMLWQCHQDTQIFFLKCLWPDFDLWYFLPVLVEWQWRQKQRERDEKPKRHLKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHA1</accession>
    <name>G4NHA1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719978.1">
        <property type="nucleotide sequence ID" value="XM_003719930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHA1"/>
    <dbReference type="STRING" id="242507.G4NHA1"/>
    <dbReference type="GeneID" id="2677192"/>
    <dbReference type="KEGG" id="mgr:MGG_03898"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03898"/>
    <dbReference type="eggNOG" id="ENOG502R21Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_529976_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHA1"/>
    <dbReference type="OMA" id="KCKETGC"/>
    <dbReference type="OrthoDB" id="4847120at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="567" mass="61467" checksum="47DD8B2E0B63A23F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHB1</accession>
    <name>G4NHB1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Histidine acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_03890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719988.1">
        <property type="nucleotide sequence ID" value="XM_003719940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHB1"/>
    <dbReference type="GeneID" id="2677477"/>
    <dbReference type="KEGG" id="mgr:MGG_03890"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03890"/>
    <dbReference type="eggNOG" id="ENOG502SM2K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023111_0_1_1"/>
    <dbReference type="InParanoid" id="G4NHB1"/>
    <dbReference type="OMA" id="STQEWCL"/>
    <dbReference type="OrthoDB" id="258392at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF127">
        <property type="entry name" value="HISTIDINE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466271" description="Histidine acid phosphatase" evidence="4">
        <location>
            <begin position="22"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="466"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="500"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="506"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="517"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA47621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="606" mass="65110" checksum="16229D9DFFEC8F20" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHB2</accession>
    <name>G4NHB2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719989.1">
        <property type="nucleotide sequence ID" value="XM_003719941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHB2"/>
    <dbReference type="GeneID" id="12987113"/>
    <dbReference type="KEGG" id="mgr:MGG_17731"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17731"/>
    <dbReference type="HOGENOM" id="CLU_193137_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHB2"/>
    <dbReference type="OMA" id="ANSGQCG"/>
    <dbReference type="OrthoDB" id="5988651at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="64" mass="6441" checksum="582760181C5D6790" modified="2011-12-14" version="1">MSGNSNQMTKDAASRIQSSSDKPSNQTGDKGDGFSSRAQSAADKNANAAAAASGGGNHGKVWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHP9</accession>
    <name>G4NHP9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720126.1">
        <property type="nucleotide sequence ID" value="XM_003720078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHP9"/>
    <dbReference type="SMR" id="G4NHP9"/>
    <dbReference type="GeneID" id="12987167"/>
    <dbReference type="KEGG" id="mgr:MGG_17763"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17763"/>
    <dbReference type="HOGENOM" id="CLU_3014656_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHP9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="56" mass="6427" checksum="F9467C649014AB8A" modified="2011-12-14" version="1">MFNFSVPRMVNFDDLRKRGLRSGGANLKLKHVTTRLQQRLSALEVLQSHARCKPCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIK5</accession>
    <name>G4NIK5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720433.1">
        <property type="nucleotide sequence ID" value="XM_003720385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIK5"/>
    <dbReference type="GeneID" id="12987340"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17842"/>
    <dbReference type="eggNOG" id="ENOG502SYTK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089010_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIK5"/>
    <dbReference type="OrthoDB" id="10424663at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="280" mass="31354" checksum="F051C51EBA67FCED" modified="2011-12-14" version="1">MAACSACESRGIPKCAVSPQDSSRCVECLRSNRSGCDVLGISPAQLRKIGQQHAKLEEELEAAEEARRRADEKVRLADAKVERLRKQKKMWFEKMMRAVSRGIDDLEELDRVEREEAEQEERRRSAEVLPEVSLESLLPDSNFVWDSTFPMGPLNPSLLDEMNVLAQHSVGSSGGMVSSPGRPLTSGNGRWCFLRSSSFSWLTCSQIQLLIVLAERFLAILEVVEGFPSVFFVSIVFPFNKVLCFAVVSSVVEYSFNVVGLFCVDLDRFLCAGAVWCRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIU0</accession>
    <name>G4NIU0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fatty acid synthase subunit alpha</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
            <ecNumber evidence="4">2.3.1.41</ecNumber>
            <ecNumber evidence="2">2.3.1.86</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="29" type="ORF">MGG_12154</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="29 30" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="30">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 4n H(+) = a long-chain-acyl-CoA + n CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.86"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 22">Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EC" id="2.3.1.41" evidence="4"/>
    <dbReference type="EC" id="2.3.1.86" evidence="2"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719713.1">
        <property type="nucleotide sequence ID" value="XM_003719665.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NIU0"/>
    <dbReference type="FunCoup" id="G4NIU0">
        <property type="interactions" value="324"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NIU0"/>
    <dbReference type="GeneID" id="5049911"/>
    <dbReference type="KEGG" id="mgr:MGG_12154"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12154"/>
    <dbReference type="eggNOG" id="ENOG502QQJX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000114_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIU0"/>
    <dbReference type="OMA" id="FPTLPDW"/>
    <dbReference type="OrthoDB" id="4251012at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004321">
        <property type="term" value="F:fatty-acyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101026">
        <property type="term" value="P:mitotic nuclear membrane biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900535">
        <property type="term" value="P:palmitic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00828">
        <property type="entry name" value="elong_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08950">
        <property type="entry name" value="KR_fFAS_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.20:FF:000005">
        <property type="entry name" value="Fatty acid synthase alpha subunit FasA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2490:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.25.70:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040899">
        <property type="entry name" value="Fas_alpha_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047224">
        <property type="entry name" value="FAS_alpha_su_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026025">
        <property type="entry name" value="FAS_alpha_yeast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041550">
        <property type="entry name" value="FASI_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18325">
        <property type="entry name" value="Fas_alpha_ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18314">
        <property type="entry name" value="FAS_I_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000454">
        <property type="entry name" value="FAS_yeast_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 24" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 24" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 22 25" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 22" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="27">
        <location>
            <begin position="140"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="28">
        <location>
            <begin position="1090"/>
            <end position="1627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="26">
        <location>
            <begin position="1324"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="26">
        <location>
            <begin position="1324"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="23">
        <location>
            <position position="1273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1743"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1745"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1843"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="1844"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="25">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRNR" id="PIRNR000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PIRSR" id="PIRSR000454-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="EHA47346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1859" mass="204305" checksum="834A39A1752901A4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJP6</accession>
    <name>G4NJP6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721205.1">
        <property type="nucleotide sequence ID" value="XM_003721157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJP6"/>
    <dbReference type="GeneID" id="5050528"/>
    <dbReference type="KEGG" id="mgr:MGG_12654"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12654"/>
    <dbReference type="HOGENOM" id="CLU_2306675_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJP6"/>
    <dbReference type="OrthoDB" id="10308142at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466417" evidence="1">
        <location>
            <begin position="19"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="100" mass="10404" checksum="2E2219D3ED41ADC3" modified="2011-12-14" version="1">MQFSQVLAILALGVSVNALPTGGLPGSSELAAQDGTLAARTIVDECPKCHGSDWGCTSDHCIKHGQAKHDALAPRSQPHGPEPQYPCMKCQGAGYGCTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKB6</accession>
    <name>G4NKB6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_03091</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Tom5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720582.1">
        <property type="nucleotide sequence ID" value="XM_003720534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKB6"/>
    <dbReference type="SMR" id="G4NKB6"/>
    <dbReference type="GeneID" id="2682644"/>
    <dbReference type="KEGG" id="mgr:MGG_03091"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03091"/>
    <dbReference type="eggNOG" id="ENOG502RPNV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_209440_1_0_1"/>
    <dbReference type="InParanoid" id="G4NKB6"/>
    <dbReference type="OMA" id="FAIDMAS"/>
    <dbReference type="OrthoDB" id="4150500at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005742">
        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006626">
        <property type="term" value="P:protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019603">
        <property type="entry name" value="Tom5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28188">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28188:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10642">
        <property type="entry name" value="Tom5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA45839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="50" mass="5625" checksum="EB78B2741251E36B" modified="2011-12-14" version="1">MFGGFEPPQLSEEQLRMAEEEATFAVKHFVAASVILYFSPFAIDVVSKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKI3</accession>
    <name>G4NKI3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720601.1">
        <property type="nucleotide sequence ID" value="XM_003720553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKI3"/>
    <dbReference type="STRING" id="242507.G4NKI3"/>
    <dbReference type="GeneID" id="5050404"/>
    <dbReference type="KEGG" id="mgr:MGG_12520"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12520"/>
    <dbReference type="HOGENOM" id="CLU_1825676_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKI3"/>
    <dbReference type="OMA" id="QEHWASK"/>
    <dbReference type="OrthoDB" id="4916200at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA45858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="141" mass="15688" checksum="11FF1A5F118B8E96" modified="2011-12-14" version="1">MKIRTHYPHSPDRLAVDGSIGWSDISMRRPNQPEFDKMHSFHGRDDAPTSSRPRETITAVSAAALKETYADGSMRVHRSFAAGPRDCVGKTLTYTEMRLNVAKTILYSDVQLLPGQEHWASKQRIIVLQKGPVDGQVDAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKX0</accession>
    <name>G4NKX0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721405.1">
        <property type="nucleotide sequence ID" value="XM_003721357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKX0"/>
    <dbReference type="GeneID" id="5051383"/>
    <dbReference type="KEGG" id="mgr:MGG_14023"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14023"/>
    <dbReference type="HOGENOM" id="CLU_2705310_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKX0"/>
    <dbReference type="OrthoDB" id="10295648at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="73" mass="8277" checksum="35CF33425A4A205D" modified="2011-12-14" version="1">MKSRQLPSDESSVRLKARGRVSEQTYVVLLAAFSEMRSISPQSPESPKVPKPRILRTGKHHLHFGARFSCEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL47</accession>
    <name>G4NL47_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02977</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720723.1">
        <property type="nucleotide sequence ID" value="XM_003720675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL47"/>
    <dbReference type="GeneID" id="2682530"/>
    <dbReference type="KEGG" id="mgr:MGG_02977"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02977"/>
    <dbReference type="HOGENOM" id="CLU_453466_0_0_1"/>
    <dbReference type="InParanoid" id="G4NL47"/>
    <dbReference type="OrthoDB" id="5224834at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA45980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="602" mass="68350" checksum="225CC0B878A2C495" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH76</accession>
    <name>G5EH76_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short chain oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g1120</name>
        <name evidence="3" type="ORF">MGG_10341</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
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        <property type="protein sequence ID" value="EAQ71713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720477.1">
        <property type="nucleotide sequence ID" value="XM_003720429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH76"/>
    <dbReference type="SMR" id="G5EH76"/>
    <dbReference type="GeneID" id="2681916"/>
    <dbReference type="KEGG" id="mgr:MGG_10341"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10341"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="OMA" id="FWASIEQ"/>
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        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
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    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="27879" checksum="3FDD14FB37E982A3" modified="2011-12-14" version="1">MSTYLITGASRGLGLAFVKNLQERPPSEVSKVFGTVRAEPSAELQQLADSSQGRVVIIHMILTDKESVATGVEQVKEKLDGRGLDVLINNAGIIEYDKSVEEMDTLRRMLETNVEAVHYVTAAFLPLLRQGKQKKIVNIGSSVCSMAHARKWMISKQYAYKISKTALNALTVQYAYSLEEEGFGVFSICPGWVKTDMTSYTADLDASTSVEGVLKATAKDNKDLNGKFLKVHIPGMEVRPGAYHEYNGAEIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHN8</accession>
    <name>G5EHN8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g1084</name>
        <name evidence="2" type="ORF">MGG_14211</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720517.1">
        <property type="nucleotide sequence ID" value="XM_003720469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHN8"/>
    <dbReference type="GeneID" id="5048704"/>
    <dbReference type="KEGG" id="mgr:MGG_14211"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14211"/>
    <dbReference type="HOGENOM" id="CLU_2740538_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ71677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA45774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="71" mass="7892" checksum="948E4781E3D6E8E3" modified="2011-12-14" version="1">MVAKYIVRGGGGGVVKAVEACRHQQGMVWPRAGVTEQWDVVALLIIVPVLHVLHKEECIDIIGEEAWKFVR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-07-27" modified="2025-06-18" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RF35</accession>
    <accession>G4NC00</accession>
    <name>AMPP1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Probable Xaa-Pro aminopeptidase P</fullName>
            <shortName>AMPP</shortName>
            <shortName>Aminopeptidase P</shortName>
            <ecNumber>3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Prolidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">AMPP</name>
        <name type="ORF">MGG_00476</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="EHA49003" version="1"/>
        </conflict>
        <text>Extended N-terminus.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49003.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718587.1">
        <property type="nucleotide sequence ID" value="XM_003718539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RF35"/>
    <dbReference type="SMR" id="A4RF35"/>
    <dbReference type="FunCoup" id="A4RF35">
        <property type="interactions" value="387"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RF35"/>
    <dbReference type="MEROPS" id="M24.A10"/>
    <dbReference type="GeneID" id="2674217"/>
    <dbReference type="KEGG" id="mgr:MGG_00476"/>
    <dbReference type="eggNOG" id="KOG2413">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A4RF35"/>
    <dbReference type="OrthoDB" id="9995434at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000010">
        <property type="entry name" value="Probable Xaa-Pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000007">
        <property type="entry name" value="Xaa-Pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000003">
        <property type="entry name" value="Xaa-pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0031">Aminopeptidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0482">Metalloprotease</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000411794" description="Probable Xaa-Pro aminopeptidase P">
        <location>
            <begin position="1"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="524"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="538"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="538"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="618" mass="68502" checksum="7D213E61DDC64201" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML21</accession>
    <name>G4ML21_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
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                <person name="Fitzgerald M."/>
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                <person name="Abouelleil A."/>
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                <person name="Arachchi H.M."/>
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                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
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                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
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                <person name="Montmayeur A."/>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Chapman S.B."/>
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                <person name="Dunbar C."/>
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                <person name="Gearin G."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="519" mass="58999" checksum="3E78D55BB6D20BC2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MML8</accession>
    <name>G4MML8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BAR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710402.1">
        <property type="nucleotide sequence ID" value="XM_003710354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MML8"/>
    <dbReference type="SMR" id="G4MML8"/>
    <dbReference type="STRING" id="242507.G4MML8"/>
    <dbReference type="GeneID" id="2675810"/>
    <dbReference type="KEGG" id="mgr:MGG_05534"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05534"/>
    <dbReference type="eggNOG" id="KOG1118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034817_1_0_1"/>
    <dbReference type="InParanoid" id="G4MML8"/>
    <dbReference type="OMA" id="KSMTSYV"/>
    <dbReference type="OrthoDB" id="14167at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07593">
        <property type="entry name" value="BAR_MUG137_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="2">
        <location>
            <begin position="23"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="468" mass="51446" checksum="29523E6C11CC401B" modified="2011-12-14" version="1">MKISTPGKMNLTKKFDRAFQWAGEKMGGEAKTNLGDDFKMLEMEMALRFDGMERLQRSMNAYVKWLGRRDTFEDKEKGLAGGYLGRTMVSHGEDFESDSDFGNCLIALGRANENCAAYQEQLVADATTVWLESLERSLATMKDYQAARKKLENRRLAYDASMTKLSKARRDDYRIEEEVRSAKAKYEETTEDVCRRMQDIKDAEADSTRDLTGFLDAELEYHERCAEELRRTRENWAGANVQGSPSRSMHGGFGRPGAAALSVRSRSSTNQSLGERLSRTNTSGSTGNSSVQNYTYEEHEPAPPVRMPTIRSASRISANGAAPDIPARPGVARSNTFQGGATIERNTQSLSGSSTPSGYQPSFQQQQNAAATMSANIGSLRGQLRPVSRIVTQPREDNVFADGYDDDTTSSGDSPKWSGDRSSSPATSYGSGASQTTSTLGSRKAPPPPPSRSKKPPPPVPAKREVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMW1</accession>
    <name>G4MMW1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Berberine/berberine-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708803.1">
        <property type="nucleotide sequence ID" value="XM_003708755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMW1"/>
    <dbReference type="GeneID" id="12985681"/>
    <dbReference type="KEGG" id="mgr:MGG_16015"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16015"/>
    <dbReference type="HOGENOM" id="CLU_2782728_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMW1"/>
    <dbReference type="OMA" id="DKDIAFM"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8184" checksum="C7B16B81F3AA37E4" modified="2011-12-14" version="1">MDSIKSFAVENGADDEFLFLNYADLSQNPLGSYGDKDIAFMEKVASKYDPNGVFQRNVPGGFRLSIARTTACLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN54</accession>
    <name>G4MN54_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">beta-glucosidase</fullName>
            <ecNumber evidence="13">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_05599</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="13"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710480.1">
        <property type="nucleotide sequence ID" value="XM_003710432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN54"/>
    <dbReference type="SMR" id="G4MN54"/>
    <dbReference type="STRING" id="242507.G4MN54"/>
    <dbReference type="GeneID" id="2676126"/>
    <dbReference type="KEGG" id="mgr:MGG_05599"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05599"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_2_1_1"/>
    <dbReference type="InParanoid" id="G4MN54"/>
    <dbReference type="OMA" id="PIVQGGH"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF5">
        <property type="entry name" value="BETA-GLUCOSIDASE M-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 13" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465246" description="beta-glucosidase" evidence="14">
        <location>
            <begin position="18"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="15">
        <location>
            <begin position="687"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA57868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="767" mass="83640" checksum="D2E43436922640EC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN87</accession>
    <name>G4MN87_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708822.1">
        <property type="nucleotide sequence ID" value="XM_003708774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN87"/>
    <dbReference type="GeneID" id="2681217"/>
    <dbReference type="KEGG" id="mgr:MGG_02062"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02062"/>
    <dbReference type="eggNOG" id="ENOG502T4C1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_578797_0_0_1"/>
    <dbReference type="InParanoid" id="G4MN87"/>
    <dbReference type="OMA" id="FLEIHNT"/>
    <dbReference type="OrthoDB" id="4366798at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="401" mass="44591" checksum="24342EF325313A25" modified="2011-12-14" version="1">MNGTLPEKNYYTDSYDAKWSWPSHRFQLKPDALFTTLHERFNTRNCPIQDPYAFLLDVRLCANESNNVDDFYARLAAQKAKRVLELEEIWDNVTDLMAFDEKGLPSDRIWTCKQCNNSGISDVITPCEPMSTNDTPELHSKSFFNMIQTMSFDSMVRFFDGFVREARKERDEYYRKKRARMQRGREEGARRRAAKQDQELQDQKRAGEGSTAAAGPQDKAAGPELDVSIPAGATVPSPSVPTRDVANDPPPLSQPPSTPSSDPETSFDQSPYTPATTPSPRREQSDSRTGKRNICTASNSTTAKTANSPHTTTKHTKRGRAASEQSCEDEIIATGEASLRQPRKKRRRVSLQTESDIPAGNAQIQTSAAGTSEATCGVLREADVCGSNDGRLTEATWAHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNT8</accession>
    <name>G4MNT8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708916.1">
        <property type="nucleotide sequence ID" value="XM_003708868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNT8"/>
    <dbReference type="GeneID" id="2681262"/>
    <dbReference type="KEGG" id="mgr:MGG_02139"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02139"/>
    <dbReference type="HOGENOM" id="CLU_1982003_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNT8"/>
    <dbReference type="OrthoDB" id="3552888at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465154" evidence="1">
        <location>
            <begin position="21"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="126" mass="13581" checksum="F5E7EC05FE001109" modified="2011-12-14" version="1">MSVYKIFLGLLPLIATGVQGAALSLPSGGLQDLSVLPEGFKMAETQWEVDIRPGKKITLNGTIESVYAQLLELNPSYEIDNAEQIAARLAQLKEETTALQKSQLARRDHTECDHAGFKGSVPASAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPQ8</accession>
    <name>G4MPQ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709817.1">
        <property type="nucleotide sequence ID" value="XM_003709769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPQ8"/>
    <dbReference type="GeneID" id="5049558"/>
    <dbReference type="KEGG" id="mgr:MGG_11770"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11770"/>
    <dbReference type="HOGENOM" id="CLU_1652506_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPQ8"/>
    <dbReference type="OrthoDB" id="10615591at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="160" mass="17027" checksum="7D8CC4FC8F8F4DD1" modified="2011-12-14" version="1">MSDTLRCEFLFWLASRISPCSLCSIGHVDNICTGPSFEDRGPGQVQPRGGETAVAALPPSQVAHSGSAIPIFIEHTAHAEPWRGMPSSGAIWVHAHHIRSQLRVSTQAGGKSCLSVFVLFRSRSGVAAALGESSKHSPSRNNVEGRLSPSPSLALPLTMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQF8</accession>
    <name>G4MQF8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710756.1">
        <property type="nucleotide sequence ID" value="XM_003710708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQF8"/>
    <dbReference type="GeneID" id="2677763"/>
    <dbReference type="KEGG" id="mgr:MGG_04810"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04810"/>
    <dbReference type="HOGENOM" id="CLU_2085291_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQF8"/>
    <dbReference type="OrthoDB" id="5177142at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="117" mass="13385" checksum="63BF901BFC7CBD08" modified="2011-12-14" version="1">MCRKKLRMANVHRARRPLRQKWPPNRHVLLESYFDFTLPSATVDQSPTKRICDRRAPSVATSQTLYPNTTSEDHQLAHRLSDPLYPKSGFMATGETTITEKGSSAPMSEKMTQHETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQW0</accession>
    <name>G4MQW0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04737</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA58191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome 1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
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        <location>
            <begin position="19"/>
            <end position="126"/>
        </location>
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            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="126" mass="12801" checksum="B84601176B55F344" modified="2011-12-14" version="1">MRPLSIFGLATLAGMTASAEQAVDVNNPAKRDLQPAAIMAPKLVARVNPVVAPPVSAPKPVPGTDLTASKPPSTVDPLPQPQPPNAGSDNGPPPSANSPSRSAGHREINSVGFEVLAALVVTAYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR14</accession>
    <name>G4MR14_PYRO7</name>
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        <recommendedName>
            <fullName evidence="3">Spt20-like SEP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709161.1">
        <property type="nucleotide sequence ID" value="XM_003709113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR14"/>
    <dbReference type="STRING" id="242507.G4MR14"/>
    <dbReference type="GeneID" id="2681482"/>
    <dbReference type="KEGG" id="mgr:MGG_02385"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02385"/>
    <dbReference type="eggNOG" id="ENOG502RKFS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004682_0_0_1"/>
    <dbReference type="InParanoid" id="G4MR14"/>
    <dbReference type="OMA" id="HNYNEHI"/>
    <dbReference type="OrthoDB" id="1932706at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021950">
        <property type="entry name" value="Spt20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046468">
        <property type="entry name" value="Spt20-like_SEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13526">
        <property type="entry name" value="TRANSCRIPTION FACTOR SPT20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13526:SF8">
        <property type="entry name" value="TRANSCRIPTION FACTOR SPT20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12090">
        <property type="entry name" value="Spt20_SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spt20-like SEP" evidence="3">
        <location>
            <begin position="126"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="925"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="764"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="554"/>
            <end position="601"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="925"/>
            <end position="939"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1056" mass="113757" checksum="5E58E193D96E31DE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRK9</accession>
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        <submittedName>
            <fullName evidence="13">Nod factor export ATP-binding protein I</fullName>
        </submittedName>
    </protein>
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        <name evidence="13" type="ORF">MGG_09941</name>
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    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003709996.1"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRK9"/>
    <dbReference type="GeneID" id="2680911"/>
    <dbReference type="KEGG" id="mgr:MGG_09941"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09941"/>
    <dbReference type="eggNOG" id="KOG0059">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_001640_2_0_1"/>
    <dbReference type="InParanoid" id="G4MRK9"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="38"/>
            <end position="57"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
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            <begin position="285"/>
            <end position="309"/>
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    <feature type="transmembrane region" description="Helical" evidence="11">
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            <begin position="321"/>
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    <feature type="transmembrane region" description="Helical" evidence="11">
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            <end position="367"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="434"/>
            <end position="455"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="831"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1027"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1071"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1105"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1137"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1173"/>
            <end position="1194"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1215"/>
            <end position="1237"/>
        </location>
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        <location>
            <begin position="482"/>
            <end position="716"/>
        </location>
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            <end position="1521"/>
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        </location>
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        </source>
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        <source>
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        <source>
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        <source>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50893"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA57432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1619" mass="177991" checksum="200C037996E9DE20" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRL9</accession>
    <name>G4MRL9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA57442.1"/>
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        <property type="nucleotide sequence ID" value="XM_003710006.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MRL9"/>
    <dbReference type="GeneID" id="12985326"/>
    <dbReference type="KEGG" id="mgr:MGG_16302"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16302"/>
    <dbReference type="HOGENOM" id="CLU_2347097_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRL9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="97" mass="10507" checksum="CE1E5239817A1CEF" modified="2011-12-14" version="1">MVAITIIPLLPQTGKPHVMLYKKYGVEIKLIGTYSVRESGVVVHLSPGLLGWFAGIFDIFIIYTQGSKGEDPSILLRGLAGAVDGEVNFRAFSSVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSL5</accession>
    <name>G4MSL5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714438.1">
        <property type="nucleotide sequence ID" value="XM_003714390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSL5"/>
    <dbReference type="GeneID" id="5050079"/>
    <dbReference type="KEGG" id="mgr:MGG_14783"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14783"/>
    <dbReference type="HOGENOM" id="CLU_2886261_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSL5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="63" mass="6869" checksum="B34479846E5D7FAF" modified="2011-12-14" version="1">MFAISNRTVDATKAYLRIIDILPPVLTANRPLCSFGSETSGANWLLLSAGKVPLRSRHTPSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSM3</accession>
    <name>G4MSM3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715251.1">
        <property type="nucleotide sequence ID" value="XM_003715203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSM3"/>
    <dbReference type="GeneID" id="12985599"/>
    <dbReference type="KEGG" id="mgr:MGG_15073"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15073"/>
    <dbReference type="eggNOG" id="ENOG502S3HU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112091_2_0_1"/>
    <dbReference type="InParanoid" id="G4MSM3"/>
    <dbReference type="OMA" id="LWRMEDA"/>
    <dbReference type="OrthoDB" id="3587182at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056121">
        <property type="entry name" value="DUF7704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF1">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24803">
        <property type="entry name" value="DUF7704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7704" evidence="2">
        <location>
            <begin position="6"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="152" mass="17326" checksum="7CBD2E499625885A" modified="2011-12-14" version="1">MTSVQRIPTLYRTMLSWVEPVFCASGTVLAMFDPTRYIDTMTPHFAYDPPVHRILLDQVGAVYLLMAFNSAVVLRVTDDLRVWKAVMGGIWVSDMLHIRATVKELGVDVILNPLAWRAVDSINLGILVGMMLLRIAFIFEIGFEKQSKRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSR7</accession>
    <name>G4MSR7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mannan endo-1,6-alpha-mannosidase</fullName>
            <ecNumber evidence="3 8">3.2.1.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07101</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Random hydrolysis of (1-&gt;6)-alpha-D-mannosidic linkages in unbranched (1-&gt;6)-mannans.</text>
            <dbReference type="EC" id="3.2.1.101"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 76 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.101" evidence="3 8"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715295.1">
        <property type="nucleotide sequence ID" value="XM_003715247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSR7"/>
    <dbReference type="SMR" id="G4MSR7"/>
    <dbReference type="STRING" id="242507.G4MSR7"/>
    <dbReference type="GeneID" id="2682986"/>
    <dbReference type="KEGG" id="mgr:MGG_07101"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07101"/>
    <dbReference type="eggNOG" id="ENOG502SMCE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025694_2_1_1"/>
    <dbReference type="InParanoid" id="G4MSR7"/>
    <dbReference type="OMA" id="CGSKWYT"/>
    <dbReference type="OrthoDB" id="4187847at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008496">
        <property type="term" value="F:mannan endo-1,6-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000033">
        <property type="entry name" value="Mannan endo-1,6-alpha-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005198">
        <property type="entry name" value="Glyco_hydro_76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014480">
        <property type="entry name" value="Mannan-1_6-alpha_mannosidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145:SF38">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12145">
        <property type="entry name" value="MANNAN ENDO-1,6-ALPHA-MANNOSIDASE DCW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03663">
        <property type="entry name" value="Glyco_hydro_76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016302">
        <property type="entry name" value="Man_a_manosd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="396"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="416"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="428" mass="46658" checksum="A7315F68F5F6E1EF" modified="2011-12-14" version="1">MVQFMKSVRVAAMAISAVPKDMKISESASVQAVVKTIAADTMSYYKGSATNYVDLEAPYWWWQSGALFGAMSDYSHYTGDKSYDQTIATALLAQTGSKYDFMSPAHEGQMGNDDLGFWGFAVMSAAERNLPQPESSVPSWLKMSENIHASLASRWDTTTCGGGLLWQIFASNPNGLNYKNSVSNGAFFQLSARLARATGNQTYMDWANKIFDWSTGVGFVDQNFHVVDGADKRDDCKKVNPVSFTYTNGIYMYGAALLANMTSDRKWIDRTQKFVEASKAYFGPTATTPDILYEPACESGGTCNVDMKSHKGQLARFMWASTLMQPAIRPVVETLLLPSAQAAASTCTGGANGSQCSHRWWTGAFDNDTGLGQEMCALETIQGILAGSAAPPLRGNDIKDVRVPKQGASAPAPKRLVREERRLAARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT46</accession>
    <name>G4MT46_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">isopentenyl-diphosphate Delta-isomerase</fullName>
            <ecNumber evidence="4">5.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_07125</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>isopentenyl diphosphate = dimethylallyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23284"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="5.3.3.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:23285"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IPP isomerase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="4"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715318.1">
        <property type="nucleotide sequence ID" value="XM_003715270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT46"/>
    <dbReference type="SMR" id="G4MT46"/>
    <dbReference type="FunCoup" id="G4MT46">
        <property type="interactions" value="781"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MT46"/>
    <dbReference type="GeneID" id="2683247"/>
    <dbReference type="KEGG" id="mgr:MGG_07125"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07125"/>
    <dbReference type="eggNOG" id="KOG0142">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060552_0_2_1"/>
    <dbReference type="InParanoid" id="G4MT46"/>
    <dbReference type="OMA" id="KAPFDNG"/>
    <dbReference type="OrthoDB" id="510307at2759"/>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045337">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009240">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02885">
        <property type="entry name" value="NUDIX_IPP_Isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000012">
        <property type="entry name" value="Isopentenyl-diphosphate Delta-isomerase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011876">
        <property type="entry name" value="IsopentenylPP_isomerase_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02150">
        <property type="entry name" value="IPP_isom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885:SF0">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018427">
        <property type="entry name" value="Isopntndiph_ism"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0752">Steroid biosynthesis</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="13">
        <location>
            <begin position="74"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA55511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="254" mass="28920" checksum="888558D7C8222583" modified="2011-12-14" version="1">MSSTTTTTAQPITAETILSLFPDIDTSGEALDGHDEEQIRLMDEVCIVVDENDMPIGKGSKKICHLMTNIEKGLLHRAFSVFLFNDKNELLLQQRATEKITFPDMWTNTCCSHPLGIPGETGSNLPDSIMGVKRAAQRKLDHELGIKKEQVPLENFHFLTRIHYKAPSDGKWGEHEVDYILFIKANVDLDINKNEVQATQYTSADGLKAFFKDPAAKFTPWFKLICESMLFEWWQHLDSGLEKYTNEQGIRRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT69</accession>
    <name>G4MT69_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715341.1">
        <property type="nucleotide sequence ID" value="XM_003715293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT69"/>
    <dbReference type="GeneID" id="2683266"/>
    <dbReference type="KEGG" id="mgr:MGG_07144"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07144"/>
    <dbReference type="HOGENOM" id="CLU_2794436_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT69"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="68" mass="7285" checksum="D74AE9FFE0EEEF44" modified="2011-12-14" version="1">MSNNQASQNAAVATKDDAASIMSSSTAASTTKPHKDQKDFTKSKKDRADNKKVTDSASILRAQMNINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT90</accession>
    <name>G4MT90_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15549</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713643.1">
        <property type="nucleotide sequence ID" value="XM_003713595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT90"/>
    <dbReference type="GeneID" id="12987140"/>
    <dbReference type="KEGG" id="mgr:MGG_15549"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15549"/>
    <dbReference type="HOGENOM" id="CLU_2942220_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT90"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="60" mass="7008" checksum="8E6D119E581337CE" modified="2011-12-14" version="1">MWEICMWDPHDQTGPLGRKELRGNFHKGITPREIVKQIRYSLLYGYGTMGDNEVTDPGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTJ3</accession>
    <name>G4MTJ3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715358.1">
        <property type="nucleotide sequence ID" value="XM_003715310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTJ3"/>
    <dbReference type="SMR" id="G4MTJ3"/>
    <dbReference type="STRING" id="242507.G4MTJ3"/>
    <dbReference type="GeneID" id="2683143"/>
    <dbReference type="KEGG" id="mgr:MGG_07160"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07160"/>
    <dbReference type="eggNOG" id="ENOG502RJG3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_473319_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTJ3"/>
    <dbReference type="OMA" id="MHEAFTD"/>
    <dbReference type="OrthoDB" id="4448936at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="17"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="543"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="436"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="543"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="576" mass="63901" checksum="CB69EAB7F0D5807F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTY5</accession>
    <name>G4MTY5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">IdgA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_14801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714586.1">
        <property type="nucleotide sequence ID" value="XM_003714538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTY5"/>
    <dbReference type="SMR" id="G4MTY5"/>
    <dbReference type="STRING" id="242507.G4MTY5"/>
    <dbReference type="GeneID" id="5050248"/>
    <dbReference type="KEGG" id="mgr:MGG_14801"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14801"/>
    <dbReference type="eggNOG" id="KOG3009">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012201_3_0_1"/>
    <dbReference type="InParanoid" id="G4MTY5"/>
    <dbReference type="OMA" id="FNCIIAT"/>
    <dbReference type="OrthoDB" id="198885at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="YeiC_kinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="entry name" value="Indigoidine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="Indigoidine synthase A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="chain" id="PRO_5003465505" evidence="6">
        <location>
            <begin position="36"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="7">
        <location>
            <begin position="409"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="7">
        <location>
            <begin position="709"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="775" mass="82589" checksum="BE60BBC581353E91" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU83</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15580</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003713723.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MU83"/>
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    <dbReference type="KEGG" id="mgr:MGG_15580"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15580"/>
    <dbReference type="eggNOG" id="ENOG502RABE">
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    <dbReference type="HOGENOM" id="CLU_293894_0_0_1"/>
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    <dbReference type="OrthoDB" id="5415512at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="254"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="737"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
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        <location>
            <begin position="49"/>
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        </location>
    </feature>
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        <location>
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            <end position="99"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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    </feature>
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    </feature>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUD1</accession>
    <name>G4MUD1_PYRO7</name>
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            <fullName evidence="5 13">Phosphomannomutase</fullName>
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        <name evidence="14" type="ORF">MGG_01637</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <text evidence="13">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
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    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>alpha-D-mannose 1-phosphate = D-mannose 6-phosphate</text>
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        </reaction>
    </comment>
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        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.</text>
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    <comment type="subunit">
        <text evidence="4 13">Homodimer.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
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    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the eukaryotic PMM family.</text>
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        <property type="reaction ID" value="UER00424"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
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        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="9 13" id="KW-0413">Isomerase</keyword>
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    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
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        <location>
            <position position="19"/>
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    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA54818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="264" mass="30086" checksum="F45417274B1E4483" modified="2011-12-14" version="1">MSYPPLDQRPLKDTICLFDVDETLTPARKRVSPEMLDLLSRLRQKCAIGYVGGSDLSKQEEQLGTSDVSVKKLFDYCFPENGLAAFKSGEPLASTSFIAWIGEDRYKELVRFILHYVADLEIPIKRGTFLEFRNGMINVSPIGRNASSQERKDFNAYDKVHQVRVKFVEALKEKFADFGLTFSIGGEISFDIFPKGWDKTYCLNHLEAEAKKEGGVEYKTIHFFGDKYMEGGNDYEIYSDPRTIGHAVDSPQDTMKELKKLFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUT5</accession>
    <name>G4MUT5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_01683</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714672.1">
        <property type="nucleotide sequence ID" value="XM_003714624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUT5"/>
    <dbReference type="SMR" id="G4MUT5"/>
    <dbReference type="FunCoup" id="G4MUT5">
        <property type="interactions" value="546"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUT5"/>
    <dbReference type="MEROPS" id="C12.002"/>
    <dbReference type="GeneID" id="2679360"/>
    <dbReference type="KEGG" id="mgr:MGG_01683"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01683"/>
    <dbReference type="eggNOG" id="KOG1415">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054406_0_2_1"/>
    <dbReference type="InParanoid" id="G4MUT5"/>
    <dbReference type="OMA" id="IDLHYVC"/>
    <dbReference type="OrthoDB" id="427186at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000008">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="19"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="252" mass="27129" checksum="61E089029F6F4AE5" modified="2011-12-14" version="1">MASSTGNPAAPEVGGTRPAFIPLEANPELMTELVHGLGLSSALQMHDVFSIDDPEMLAFIPRPALALLLVFPVSAIYESHRLAEDSLLADYAGKGPDEPVMWFRQTIRNACGMMGILHATLNGPAKNFIDADSTLDKLLKDATPLEPAARSKLIETNGALAQQNKAVASRGDTAAPEATDDVDLHYVCFVKAEDGTLWELDGRRKGPLARGKLEDSEDVLSEKALVLGPRKFLEREGGDMRFSCVALAQSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUU2</accession>
    <name>G4MUU2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rho GDP-dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01689</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rho GDI family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714679.1">
        <property type="nucleotide sequence ID" value="XM_003714631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUU2"/>
    <dbReference type="SMR" id="G4MUU2"/>
    <dbReference type="FunCoup" id="G4MUU2">
        <property type="interactions" value="433"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUU2"/>
    <dbReference type="GeneID" id="2679366"/>
    <dbReference type="KEGG" id="mgr:MGG_01689"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01689"/>
    <dbReference type="eggNOG" id="KOG3205">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076228_1_0_1"/>
    <dbReference type="InParanoid" id="G4MUU2"/>
    <dbReference type="OMA" id="YKPTAAK"/>
    <dbReference type="OrthoDB" id="1683373at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005094">
        <property type="term" value="F:Rho GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.50.30:FF:000001">
        <property type="entry name" value="Rho GDP-dissociation inhibitor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.30">
        <property type="entry name" value="Coagulation Factor XIII, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000406">
        <property type="entry name" value="Rho_GDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024792">
        <property type="entry name" value="RhoGDI_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980:SF3">
        <property type="entry name" value="LD16419P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980">
        <property type="entry name" value="RHO GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02115">
        <property type="entry name" value="Rho_GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00492">
        <property type="entry name" value="RHOGDI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00054143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="199" mass="22630" checksum="F291ADF471D0A739" modified="2011-12-14" version="1">MASHHDEDTMPEETQGYKLSQPKQSLAEYSQMDAGDESLQRYKQSLGLGQGKDLSDPNDPRVCIIYSLTMESPGRDPVKIDLRTPGSEKTLKDHPFKIKEGAKFTMVADFKVQHEILSGLHYVQVVKRKGIKVSKDSEMIGSYAPNTDKQPIYTKKFQEEEAPTGMLARGHYNAISSFVDDDKKKHLEFEWSFDIAKDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV14</accession>
    <name>G4MV14_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715555.1">
        <property type="nucleotide sequence ID" value="XM_003715507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV14"/>
    <dbReference type="SMR" id="G4MV14"/>
    <dbReference type="GeneID" id="12986705"/>
    <dbReference type="KEGG" id="mgr:MGG_15905"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15905"/>
    <dbReference type="HOGENOM" id="CLU_2038516_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV14"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="121" mass="13572" checksum="3B52E700B435F448" modified="2011-12-14" version="1">MARIAASLMKESTCAPKKTPIEAWERPRPEYPPQQPFFARTGQIQGPRGGKKGDGTRDFSPCQFKRLIPLGATLSQIADQINPFACLTRQWSWKRAGSGRWETEAREPASPQQMALTEIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV76</accession>
    <name>G4MV76_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane and coiled-coil domain-containing protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08873</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713898.1">
        <property type="nucleotide sequence ID" value="XM_003713850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV76"/>
    <dbReference type="STRING" id="242507.G4MV76"/>
    <dbReference type="ESTHER" id="maggr-a4rlz4">
        <property type="family name" value="Duf_726"/>
    </dbReference>
    <dbReference type="GeneID" id="2679859"/>
    <dbReference type="KEGG" id="mgr:MGG_08873"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08873"/>
    <dbReference type="eggNOG" id="KOG2385">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007407_3_0_1"/>
    <dbReference type="InParanoid" id="G4MV76"/>
    <dbReference type="OMA" id="NKFSRFW"/>
    <dbReference type="OrthoDB" id="277931at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF22">
        <property type="entry name" value="DUF726 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="84"/>
        </location>
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            <end position="776"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA54091.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="798" mass="87008" checksum="770764DCBEF26293" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55803.1"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA55803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVP0</accession>
    <name>G4MVP0_PYRO7</name>
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        <recommendedName>
            <fullName evidence="8">Bromodomain-containing factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_08925</name>
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    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA54149.1"/>
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    <dbReference type="GeneID" id="2679911"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_08925"/>
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        <property type="entry name" value="Bromodomain-like_sf"/>
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        <property type="entry name" value="Bromodomain_CS"/>
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        <property type="entry name" value="NET_sf"/>
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        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
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    </dbReference>
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        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
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        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
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        <location>
            <begin position="527"/>
            <end position="543"/>
        </location>
    </feature>
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        </location>
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        <location>
            <begin position="712"/>
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        </location>
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            <end position="738"/>
        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
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            <end position="995"/>
        </location>
    </feature>
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        <location>
            <begin position="1008"/>
            <end position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA54149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1021" mass="109078" checksum="26BCEFAF9331219F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVT8</accession>
    <name>G4MVT8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="G4MVT8"/>
    <dbReference type="GeneID" id="12985416"/>
    <dbReference type="KEGG" id="mgr:MGG_15771"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15771"/>
    <dbReference type="HOGENOM" id="CLU_2671544_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVT8"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="75" mass="7985" checksum="8F672FF9C7910549" modified="2011-12-14" version="1">MSPRAIPFNFSHRTAILGCVLSGAMHNTRPDGSDGGDQPVVPVKKFEPDIFPGGLRRLACGPVHGEDPTMIKGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWF2</accession>
    <name>G4MWF2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Diacylglycerol pyrophosphate phosphatase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_12462</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA55912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003715671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWF2"/>
    <dbReference type="FunCoup" id="G4MWF2">
        <property type="interactions" value="223"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MWF2"/>
    <dbReference type="GeneID" id="5051057"/>
    <dbReference type="KEGG" id="mgr:MGG_12462"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12462"/>
    <dbReference type="eggNOG" id="KOG3030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021458_6_1_1"/>
    <dbReference type="InParanoid" id="G4MWF2"/>
    <dbReference type="OMA" id="WFSYRRY"/>
    <dbReference type="OrthoDB" id="10030083at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000810">
        <property type="term" value="F:diacylglycerol diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.144.10:FF:000017">
        <property type="entry name" value="Diacylglycerol pyrophosphate phosphatase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF35">
        <property type="entry name" value="RE23632P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="108"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="335" mass="36737" checksum="F4A309D0336AABBF" modified="2011-12-14" version="1">MAPSNDRRGGNRGDGVLDSAARFWRRSYAPDYVGFGALVAGYMVLVFFVEPFHRMFSISDLAISFPHAEHERVPVFMNIVYAAAVPLAVVVATNLATRASAHKHHVAILGLAVGLVLTSFLTDVVKNAVGRPRPDLLARCKPRPGTAENRLVDWTVCTEKEHHLLHDGWRSFPSGHSSFSFAGLGYTALFLAGQLRIFAYDGERDGEEDGSGAGKMERVVSAAHGRGLGTALFCMIPLLGATMIAISRCQDYRHDVYDVCTGALLGSVVTYWSYRRYWPRFGSYRCSEPWPSPGAVEDRGKGYARMRRDEESGVRGGGGSSAGYSGGYEMRIMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWI5</accession>
    <name>G4MWI5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714041.1">
        <property type="nucleotide sequence ID" value="XM_003713993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWI5"/>
    <dbReference type="GeneID" id="12987361"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15628"/>
    <dbReference type="eggNOG" id="ENOG502SYTK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122022_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWI5"/>
    <dbReference type="OrthoDB" id="5241776at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="192" mass="21035" checksum="DB77CAAB43A4724E" modified="2011-12-14" version="1">MPSCSACESQGIAKCAVSPRDSSRCVECVRLGRSRCDVMGVSREQLHRIAAQHSKLESELEAAEEKVLRLRRQKKMWFEKMTRAVRRGIDNLEELDRVEREEAEQEERRRSAEVLPEVSLELLLPDSNFVWDSTFPMGPLNPSLLDEINVLAQHSVGSSGGMVSSPGRSLTSGNDPTPDSTGGVIPGNSGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWY4</accession>
    <name>G4MWY4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714083.1">
        <property type="nucleotide sequence ID" value="XM_003714035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWY4"/>
    <dbReference type="SMR" id="G4MWY4"/>
    <dbReference type="STRING" id="242507.G4MWY4"/>
    <dbReference type="GeneID" id="2679541"/>
    <dbReference type="KEGG" id="mgr:MGG_01195"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01195"/>
    <dbReference type="eggNOG" id="ENOG502S5SG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065859_1_0_1"/>
    <dbReference type="InParanoid" id="G4MWY4"/>
    <dbReference type="OMA" id="WGNGFIQ"/>
    <dbReference type="OrthoDB" id="5041285at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037459">
        <property type="entry name" value="RhgT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43695:SF2">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G17250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465630" evidence="1">
        <location>
            <begin position="17"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="238" mass="25503" checksum="3C0F7325460CF550" modified="2011-12-14" version="1">MKPTILLAATTSLATAAPYFVLTGDSTTAVNGGWGDGFLSFLQGGAAGWNTAKSGATTASFRAQGLWDGAVRRVREKVGEYKPVFVTIQFGHNDQKEAAGISLDQFQRNLEDMVREVAGAGGVPILITSLTRRTFSGGSVVRNLENERQRTIAAAAAAGAQYLDLNAKSTDYINAVGDADGRRYDLAQGDRTHLNKAAEVVFGRMVADLLLEKKGELRAFLRDNSTISDAIRDGRFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX95</accession>
    <name>G4MX95_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">p450 monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_12478</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715800.1">
        <property type="nucleotide sequence ID" value="XM_003715752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX95"/>
    <dbReference type="SMR" id="G4MX95"/>
    <dbReference type="STRING" id="242507.G4MX95"/>
    <dbReference type="GeneID" id="5051072"/>
    <dbReference type="KEGG" id="mgr:MGG_12478"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12478"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_3_1"/>
    <dbReference type="InParanoid" id="G4MX95"/>
    <dbReference type="OMA" id="WLRNTIQ"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA55993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="532" mass="59100" checksum="F5CA66BBC7E22CC4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXT5</accession>
    <name>G4MXT5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Histone-lysine N-methyltransferase, H3 lysine-4 specific</fullName>
            <ecNumber evidence="3 16">2.1.1.354</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MGG_15053</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Binds RNAs which might negatively affect its histone methyltransferase activity. COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 16">
            <text>L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60260"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.354"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60272"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60268"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="Rhea" id="RHEA-COMP:15543"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the COMPASS (Set1C) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the Set1C/COMPASS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.1.1.354" evidence="3 16"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715029.1">
        <property type="nucleotide sequence ID" value="XM_003714981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXT5"/>
    <dbReference type="SMR" id="G4MXT5"/>
    <dbReference type="STRING" id="242507.G4MXT5"/>
    <dbReference type="GeneID" id="12985533"/>
    <dbReference type="KEGG" id="mgr:MGG_15053"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15053"/>
    <dbReference type="eggNOG" id="KOG1080">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004391_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXT5"/>
    <dbReference type="OMA" id="CHMTALF"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140999">
        <property type="term" value="F:histone H3K4 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20072">
        <property type="entry name" value="SET_SET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024657">
        <property type="entry name" value="COMPASS_Set1_N-SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044570">
        <property type="entry name" value="Set1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017111">
        <property type="entry name" value="Set1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024636">
        <property type="entry name" value="SET_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11764">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11767">
        <property type="entry name" value="SET_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037104">
        <property type="entry name" value="Histone_H3-K4_mtfrase_Set1_fun"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01291">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51572">
        <property type="entry name" value="SAM_MT43_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 16" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5 16" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 16 20" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 16 20" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="18">
        <location>
            <begin position="1136"/>
            <end position="1253"/>
        </location>
    </feature>
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    <sequence length="1278" mass="142873" checksum="87721D3BCEA41D01" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY61</accession>
    <name>G4MY61_PYRO7</name>
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            <fullName evidence="3">glycerol kinase</fullName>
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            <fullName evidence="9">ATP:glycerol 3-phosphotransferase</fullName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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    <comment type="pathway">
        <text evidence="1">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
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        <text evidence="2 10">Belongs to the FGGY kinase family.</text>
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        <property type="term" value="F:ATP binding"/>
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        <property type="term" value="F:glycerol kinase activity"/>
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        <property type="term" value="P:glycerol catabolic process"/>
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    </dbReference>
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        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
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        <property type="entry name" value="ATPase_NBD"/>
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        <property type="entry name" value="PRK00047.1"/>
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        <property type="entry name" value="GLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="GlpK"/>
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        <location>
            <begin position="72"/>
            <end position="323"/>
        </location>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00043149"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00370"/>
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        <source>
            <dbReference type="Pfam" id="PF02782"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA54392.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYP8</accession>
    <name>G4MYP8_PYRO7</name>
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        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="9" type="ORF">MGG_15057</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    <dbReference type="KEGG" id="mgr:MGG_15057"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15057"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="2" id="KW-0813">Transport</keyword>
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        <source>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ17</accession>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003714243.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MZ17"/>
    <dbReference type="SMR" id="G4MZ17"/>
    <dbReference type="GeneID" id="12984632"/>
    <dbReference type="KEGG" id="mgr:MGG_15679"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15679"/>
    <dbReference type="HOGENOM" id="CLU_2868108_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ17"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="64" mass="6942" checksum="CAA1ED223469ACB5" modified="2011-12-14" version="1">MGRYSQQRIGSFGLGTRGPNWAGFPQKSAKSAQGSKPQQDFQRTAARLFNHLHLLASAARVANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0I8</accession>
    <name>G4N0I8_PYRO7</name>
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        <recommendedName>
            <fullName evidence="5">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_15244</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PRA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712926.1">
        <property type="nucleotide sequence ID" value="XM_003712878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0I8"/>
    <dbReference type="FunCoup" id="G4N0I8">
        <property type="interactions" value="272"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N0I8"/>
    <dbReference type="GeneID" id="12985808"/>
    <dbReference type="KEGG" id="mgr:MGG_15244"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15244"/>
    <dbReference type="eggNOG" id="KOG3142">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_103851_1_1_1"/>
    <dbReference type="InParanoid" id="G4N0I8"/>
    <dbReference type="OMA" id="PWTVFFN"/>
    <dbReference type="OrthoDB" id="63113at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004895">
        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317:SF0">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="176" mass="19579" checksum="CB3F0281F06CF654" modified="2011-12-14" version="1">MSRIQIPLDVITSRFNLSERFSGLNSGSLTSRFSNLRPLSEFFDFKRLSKPQNFGEVQSRVNYNLSYFSSNYSVIFVMLCIYTLLTNWWLLFDIIFVTLGMFLIGKLDGRDLEIGTFKASPSQLYTGLLVIAIPVGLIASPFSTIAWLIGASGVTIIGHAALMDKPIDEAFSGEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0V5</accession>
    <name>G4N0V5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712140.1">
        <property type="nucleotide sequence ID" value="XM_003712092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0V5"/>
    <dbReference type="GeneID" id="2684184"/>
    <dbReference type="KEGG" id="mgr:MGG_05791"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05791"/>
    <dbReference type="HOGENOM" id="CLU_1740908_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0V5"/>
    <dbReference type="OMA" id="KFYASQP"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="150" mass="16253" checksum="3F8D48A2472E78CF" modified="2011-12-14" version="1">MSGKVYLITGVNRGIGRGLFKFYASQPNNTVIGTVRDLKHAQALLDEPRGTDTNLIITKLDGSSKTDPYSAVRILLPPPPPRLPVARITRLAIDNNHPPVPSSPHLLGTSSPWLQTTDSSAVWTQAPLDEEPSTAVRRILRAPEGTGSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1E3</accession>
    <name>G4N1E3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mis6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_09521</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-I/CTF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712221.1">
        <property type="nucleotide sequence ID" value="XM_003712173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1E3"/>
    <dbReference type="SMR" id="G4N1E3"/>
    <dbReference type="STRING" id="242507.G4N1E3"/>
    <dbReference type="GeneID" id="2680476"/>
    <dbReference type="KEGG" id="mgr:MGG_09521"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09521"/>
    <dbReference type="eggNOG" id="ENOG502QU9H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023256_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1E3"/>
    <dbReference type="OMA" id="RVFKNYY"/>
    <dbReference type="OrthoDB" id="6347512at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000939">
        <property type="term" value="C:inner kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034080">
        <property type="term" value="P:CENP-A containing chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22647">
        <property type="entry name" value="CTF3_NTD_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012485">
        <property type="entry name" value="CENP-I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48208">
        <property type="entry name" value="CENTROMERE PROTEIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48208:SF2">
        <property type="entry name" value="CENTROMERE PROTEIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07778">
        <property type="entry name" value="CENP-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="725" mass="80159" checksum="1F5DC2C5A0E68EFE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1K6</accession>
    <name>G4N1K6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Endoglucanase family 5 glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_07846</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713080.1">
        <property type="nucleotide sequence ID" value="XM_003713032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1K6"/>
    <dbReference type="SMR" id="G4N1K6"/>
    <dbReference type="FunCoup" id="G4N1K6">
        <property type="interactions" value="48"/>
    </dbReference>
    <dbReference type="GeneID" id="2683773"/>
    <dbReference type="KEGG" id="mgr:MGG_07846"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07846"/>
    <dbReference type="eggNOG" id="ENOG502RDG8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031875_1_1_1"/>
    <dbReference type="InParanoid" id="G4N1K6"/>
    <dbReference type="OMA" id="CKMLHTE"/>
    <dbReference type="OrthoDB" id="1887033at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000130">
        <property type="entry name" value="Endoglucanase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF13">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="6">
        <location>
            <begin position="89"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA53273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="487" mass="56441" checksum="CAE0949B529911CD" modified="2011-12-14" version="1">MCGDKLQWYFSGTYAMSCKMLRVSGTQIVDPDGKQVLLKGAGLGGMLNMENFITGYSGHEFEHRAALAEVLGQEKADYFFSRLIHHFFTEADAALFASLGLNCLRVPFNYRHFMDDDNPSVIKKQGFELLDRIVDICAKYNIYVVLDLHAVQGGQNQDWHSDSGLNRAIFWEFKDFQDRAVQLWEALAAHYRGNPVIAGYNPLNEPADPKHTRLLAWYERCEKAIRAVDPDHMLFVDGNTYAMDFSAFPVDRPLPNTVYSCHDYSFLGFPVAEQYEGSEEQKKKLRESFRRKVGFMQQARVPIWNGEFGPVYQDPRKDGDAEATNRKRFALLKEQLQIYREFDQDVSWSIWLYKDIGYQGMVYVSPDSAYMRLIRGFVEKKQRLGLDFWGVANKDAINGDVYAPFLEKVKKEIPDHLLKKKYPNVWTFDRQVERSVREMLLSEYHGWEMAELFRGKTEAELEELASSFSLEKCVLRDELNQILKEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1L9</accession>
    <name>G4N1L9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial phosphate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_07489</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA51591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003711350.1"/>
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    <dbReference type="GeneID" id="2683409"/>
    <dbReference type="KEGG" id="mgr:MGG_07489"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07489"/>
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        <property type="component" value="Chromosome 3"/>
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        <property type="term" value="F:phosphate transmembrane transporter activity"/>
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        <property type="entry name" value="MCP_dom_sf"/>
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        <property type="entry name" value="MCP_transmembrane"/>
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        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF12">
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    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
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    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <source>
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            <dbReference type="ARBA" id="ARBA00022448"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000488"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA51591.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="308" mass="32094" checksum="19D2C37D5EED83D7" modified="2011-12-14" version="1">MGATTANAAAPPQGIDLYSRFALAGALGCSVTHGAFTPVDVVKTRIQLDPATYNKGMIGGFRQVIQNEGAGALLTGFGPTFTGYFIQGAFKFGGYEFFKKQSIDFLGLETARQNRGLVYSVSAASAEFFASIALSPLEATRIRLVSTPGFANGLVGGFTKILKNEGVGAFYSGFVPILFKQIPYTVTKFVAFEKVSEFIFSQLDKSSLSSGGQTAVNLGSGLIAGFAAAIVSQPADTMLSKINKTKGMPGEGVVSRLVKIGGELGVRGSFAGLPTRLFMVGGLTAGQFAIYGDIKKALGATNGVEIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1Q7</accession>
    <name>G4N1Q7_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">SAC3/GANP/THP3 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_07523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA51629.1"/>
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        <property type="nucleotide sequence ID" value="XM_003711388.1"/>
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        <property type="component" value="Chromosome 3"/>
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        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:mRNA export from nucleus"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="2">
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            <begin position="479"/>
            <end position="804"/>
        </location>
    </feature>
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        <location>
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            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="855"/>
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        </location>
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        <location>
            <begin position="1073"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1228"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1346"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="1423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1538"/>
            <end position="1605"/>
        </location>
    </feature>
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        <location>
            <begin position="131"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
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        <location>
            <begin position="891"/>
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        </location>
    </feature>
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        <location>
            <begin position="914"/>
            <end position="926"/>
        </location>
    </feature>
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        <location>
            <begin position="970"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="980"/>
            <end position="991"/>
        </location>
    </feature>
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        <location>
            <begin position="992"/>
            <end position="1001"/>
        </location>
    </feature>
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        <location>
            <begin position="1002"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1068"/>
        </location>
    </feature>
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        <location>
            <begin position="1078"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1129"/>
            <end position="1140"/>
        </location>
    </feature>
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        <location>
            <begin position="1228"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1244"/>
            <end position="1262"/>
        </location>
    </feature>
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        <location>
            <begin position="1263"/>
            <end position="1290"/>
        </location>
    </feature>
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        <location>
            <begin position="1360"/>
            <end position="1371"/>
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        <location>
            <begin position="1542"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1562"/>
            <end position="1576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1648" mass="179081" checksum="3A87557DA12A059D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4N214</accession>
    <name>G4N214_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phenylacetone monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713131.1">
        <property type="nucleotide sequence ID" value="XM_003713083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N214"/>
    <dbReference type="SMR" id="G4N214"/>
    <dbReference type="STRING" id="242507.G4N214"/>
    <dbReference type="GeneID" id="2683814"/>
    <dbReference type="KEGG" id="mgr:MGG_07887"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07887"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006937_6_1_1"/>
    <dbReference type="InParanoid" id="G4N214"/>
    <dbReference type="OMA" id="WMKDTIW"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF8">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="63950" checksum="7CA4823C17D7B80D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2V7</accession>
    <name>G4N2V7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713213.1">
        <property type="nucleotide sequence ID" value="XM_003713165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2V7"/>
    <dbReference type="SMR" id="G4N2V7"/>
    <dbReference type="GeneID" id="12986122"/>
    <dbReference type="KEGG" id="mgr:MGG_16976"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16976"/>
    <dbReference type="HOGENOM" id="CLU_2250656_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2V7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="104" mass="11821" checksum="0FC7A2E096778428" modified="2011-12-14" version="1">MPRRAENAQSAIPESKAMFGSWPAGPPDTDDSHQKGRFDQSKVAIRARCSINWFLACKDLSVTEIHHLVSCAMLPLEERRRPRPLKLVRKPQFEPVVMAWLGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N375</accession>
    <name>G4N375_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712438.1">
        <property type="nucleotide sequence ID" value="XM_003712390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N375"/>
    <dbReference type="GeneID" id="2675514"/>
    <dbReference type="KEGG" id="mgr:MGG_04944"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04944"/>
    <dbReference type="eggNOG" id="ENOG502S85Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067863_1_0_1"/>
    <dbReference type="InParanoid" id="G4N375"/>
    <dbReference type="OMA" id="LKFLGHH"/>
    <dbReference type="OrthoDB" id="1859733at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021851">
        <property type="entry name" value="DUF3455"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567:SF3">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35567">
        <property type="entry name" value="MALATE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G13800)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11937">
        <property type="entry name" value="DUF3455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466057" description="Malate dehydrogenase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="27294" checksum="6A44AE78F017C1D0" modified="2011-12-14" version="1">MFSKTLLFAAALVASVSASPCKPRASGIPLPVLPSTGAVDLPAPNPSCALKAIAVGHGIQNYTCADGNATPVAAGALAVLYDVTSLYPGTPSTGLSKEAFNALTTSTLWGSNIPLNLKDPEAARPGTPASPNNGMPPSSYGAVVADPFIAPADLPQPDGAPLKFLGHHFFDAAGNPTFDLSTMNLRFSVGLKQSVDVPANADRGILDTGAVKWLMLNDNGKGLGNTGATSQVYRVITAGGVGEACSKEGAVPVASVPYTAFYWFYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3B7</accession>
    <name>G4N3B7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07666</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711602.1">
        <property type="nucleotide sequence ID" value="XM_003711554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3B7"/>
    <dbReference type="SMR" id="G4N3B7"/>
    <dbReference type="STRING" id="242507.G4N3B7"/>
    <dbReference type="CAZy" id="GH47">
        <property type="family name" value="Glycoside Hydrolase Family 47"/>
    </dbReference>
    <dbReference type="GeneID" id="2683586"/>
    <dbReference type="KEGG" id="mgr:MGG_07666"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07666"/>
    <dbReference type="eggNOG" id="KOG2431">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003818_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3B7"/>
    <dbReference type="OMA" id="FEWADWE"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF49">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="476"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="557"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="643"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="433"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA51795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="652" mass="73275" checksum="38A0712B26A01664" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3T2</accession>
    <name>G4N3T2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="4">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_05008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712512.1">
        <property type="nucleotide sequence ID" value="XM_003712464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3T2"/>
    <dbReference type="SMR" id="G4N3T2"/>
    <dbReference type="STRING" id="242507.G4N3T2"/>
    <dbReference type="GeneID" id="2675286"/>
    <dbReference type="KEGG" id="mgr:MGG_05008"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05008"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_1_1"/>
    <dbReference type="InParanoid" id="G4N3T2"/>
    <dbReference type="OMA" id="GTYAINW"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006598">
        <property type="term" value="P:polyamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000050">
        <property type="entry name" value="Aldehyde dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000012">
        <property type="entry name" value="Betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720:SF2">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="78"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="550" mass="59267" checksum="E1DF0DA3AA48C22B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3V4</accession>
    <name>G4N3V4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-strand DNA deaminase toxin A-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712534.1">
        <property type="nucleotide sequence ID" value="XM_003712486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3V4"/>
    <dbReference type="STRING" id="242507.G4N3V4"/>
    <dbReference type="GeneID" id="12985070"/>
    <dbReference type="KEGG" id="mgr:MGG_16843"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16843"/>
    <dbReference type="InParanoid" id="G4N3V4"/>
    <dbReference type="OrthoDB" id="5227818at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057517">
        <property type="entry name" value="SsdA-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24120">
        <property type="entry name" value="SsdA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Single-strand DNA deaminase toxin A-like C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="161" mass="18479" checksum="AE9A3C1CFE1DC7E6" modified="2011-12-14" version="1" fragment="single">MAFCRSSGFTLSANARDNPAGRTTDPELIKAEQGQWQACHAEKKLAIFYLRLIMARTFKDDFKDPFTGGYEFDHKQLQRFKSMNIPNRSRKAYIFLGHDPCTGCLNFLHHLQTCSGIEILVKPLPIVKEWNRPNKRYNDSRADNQQCLTGSDSDDDDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4A5</accession>
    <name>G4N4A5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711780.1">
        <property type="nucleotide sequence ID" value="XM_003711732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4A5"/>
    <dbReference type="SMR" id="G4N4A5"/>
    <dbReference type="STRING" id="242507.G4N4A5"/>
    <dbReference type="GeneID" id="2684030"/>
    <dbReference type="KEGG" id="mgr:MGG_05945"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05945"/>
    <dbReference type="eggNOG" id="ENOG502SPDA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052843_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4A5"/>
    <dbReference type="OMA" id="NSPQYMT"/>
    <dbReference type="OrthoDB" id="4151352at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="97"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="352" mass="38187" checksum="5AE42E0B7B22C9F9" modified="2011-12-14" version="1">MPKITRQSHNHLRYTANPLAMPASISTTTSQMAYYNGRSNSNMAAAASYYEPLPATHTQPPMTLPSFDPYAVAPPPPPPISIPGNNFSHGLPTPSHPHRASSGAWSAEEDQTLLAARAQGLNWSSIQSTHFPSKTSNACRKRHERLMERRGADDWDARKLERLAQEYMKVRKEIWQPLARITGEKWNVVEQKIMANGIKNLQSAARHAARRERADAGHSSAVYDDDSGVSGMTPLDDQELQYSSPSSAGISAGGSTGGSAYGAVTAAMHHPNTTAYANHNGYYVSHNQHQHQHHHGYSNSVSSTHTAGYTQNPAEDSHSPSPYLGHGQRLPSVEMGIGSLIHRGSGSGHHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4B3</accession>
    <name>G4N4B3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711788.1">
        <property type="nucleotide sequence ID" value="XM_003711740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4B3"/>
    <dbReference type="GeneID" id="12984208"/>
    <dbReference type="KEGG" id="mgr:MGG_16719"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16719"/>
    <dbReference type="HOGENOM" id="CLU_2413684_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4B3"/>
    <dbReference type="OMA" id="LCCREAR"/>
    <dbReference type="OrthoDB" id="2886613at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466577" description="Extracellular membrane protein CFEM domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="92" mass="9673" checksum="525CDBCEF8E34D59" modified="2011-12-14" version="1">MKLNSLLFLAALIGPSDACKCQKGVAWTVLCCREARGRYSNGDCAASSIGERLSAFSACCIQMKTVSDCDCPLGCAQYSSDIANGIVEALLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4B9</accession>
    <name>G4N4B9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_05956</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711794.1">
        <property type="nucleotide sequence ID" value="XM_003711746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4B9"/>
    <dbReference type="SMR" id="G4N4B9"/>
    <dbReference type="FunCoup" id="G4N4B9">
        <property type="interactions" value="791"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N4B9"/>
    <dbReference type="GeneID" id="2684019"/>
    <dbReference type="KEGG" id="mgr:MGG_05956"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05956"/>
    <dbReference type="eggNOG" id="KOG1147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001882_1_2_1"/>
    <dbReference type="InParanoid" id="G4N4B9"/>
    <dbReference type="OMA" id="CPVVDSH"/>
    <dbReference type="OrthoDB" id="10250478at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1160.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.800.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000037">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000004">
        <property type="entry name" value="Glutamyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="entry name" value="Glutamyl-trna Synthetase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.800.10">
        <property type="entry name" value="Glutamyl-tRNA Synthetase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF5">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13 17" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="14">
        <location>
            <begin position="121"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="15">
        <location>
            <begin position="428"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="16">
        <location>
            <begin position="532"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA51987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="635" mass="72345" checksum="2DAED96E72B680D2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4W5</accession>
    <name>G4N4W5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06035</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711884.1">
        <property type="nucleotide sequence ID" value="XM_003711836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4W5"/>
    <dbReference type="SMR" id="G4N4W5"/>
    <dbReference type="FunCoup" id="G4N4W5">
        <property type="interactions" value="371"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N4W5"/>
    <dbReference type="GeneID" id="2683940"/>
    <dbReference type="KEGG" id="mgr:MGG_06035"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06035"/>
    <dbReference type="eggNOG" id="KOG0544">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_12_1_1"/>
    <dbReference type="InParanoid" id="G4N4W5"/>
    <dbReference type="OMA" id="FTQATMG"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000050">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF447">
        <property type="entry name" value="FK506-BINDING PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="113" mass="11975" checksum="7E6918F922FA7AA6" modified="2011-12-14" version="1">MGVTKTTTQQGTGPSPQVGQTVVIEYTGFLKDTSKPDNKGAQFDSSVGRGDFETAIGVQRVIKGWDEGVVSMKVGEKATLDITADYGYGARGFPGAIPPNSDLIFDVYLKGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N518</accession>
    <name>G4N518_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712736.1">
        <property type="nucleotide sequence ID" value="XM_003712688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N518"/>
    <dbReference type="SMR" id="G4N518"/>
    <dbReference type="STRING" id="242507.G4N518"/>
    <dbReference type="GeneID" id="2675472"/>
    <dbReference type="KEGG" id="mgr:MGG_05194"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05194"/>
    <dbReference type="eggNOG" id="ENOG502T2QC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097996_0_0_1"/>
    <dbReference type="InParanoid" id="G4N518"/>
    <dbReference type="OMA" id="NWPTLIQ"/>
    <dbReference type="OrthoDB" id="5355007at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="156" mass="16287" checksum="B98ADDD83C7651CD" modified="2011-12-14" version="1">MSNPPTPLKVSPAATSYTAATMDSDLRSQINTLLINDELSVKIQEALLHSLNAHPANWPTQIQQHALSLLRAGDITTFPALLDKVLEDVRQSTAAAAADSSSATNGEANGKKTNGDAGADSTSNLAVPQAVVDEALKVTMDCLVDLVEFSGENGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5T0</accession>
    <name>G4N5T0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Laccase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_08523</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716025.1">
        <property type="nucleotide sequence ID" value="XM_003715977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5T0"/>
    <dbReference type="SMR" id="G4N5T0"/>
    <dbReference type="STRING" id="242507.G4N5T0"/>
    <dbReference type="GeneID" id="2678793"/>
    <dbReference type="KEGG" id="mgr:MGG_08523"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08523"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_5_0_1"/>
    <dbReference type="InParanoid" id="G4N5T0"/>
    <dbReference type="OMA" id="AYWYHAH"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13850">
        <property type="entry name" value="CuRO_1_Abr2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13876">
        <property type="entry name" value="CuRO_2_Abr2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13898">
        <property type="entry name" value="CuRO_3_Abr2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000036">
        <property type="entry name" value="L-ascorbate oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF488">
        <property type="entry name" value="LACCASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465837" evidence="9">
        <location>
            <begin position="21"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="12">
        <location>
            <begin position="36"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="10">
        <location>
            <begin position="178"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="11">
        <location>
            <begin position="505"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="394"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA49706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="640" mass="70779" checksum="11817A5F3E94B427" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5U3</accession>
    <name>G4N5U3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_08532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716038.1">
        <property type="nucleotide sequence ID" value="XM_003715990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5U3"/>
    <dbReference type="GeneID" id="2678845"/>
    <dbReference type="KEGG" id="mgr:MGG_08532"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08532"/>
    <dbReference type="HOGENOM" id="CLU_1896643_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5U3"/>
    <dbReference type="OrthoDB" id="5241954at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="134" mass="14474" checksum="3164170B3CB77DFC" modified="2011-12-14" version="1">MLTDGDADLAAPFLQRGGLGPAVDHPVLSTRSNVLSKEADQTRLFKFPLASGPQLTDAMRQVQEAADDKAAAEGKRSAGRVLAHTFVPGQLGWRTIAEDPMVKSAVERRQGAAPEWAKVENWNGKYADLTVSFK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2015-04-01" modified="2025-02-05" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5V2</accession>
    <name>CE12B_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endoglucanase cel12B</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cellulase cel12B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Endo-1,4-beta-glucanase cel12B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cel12B</name>
        <name type="ORF">MGG_08537</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2010" name="Appl. Microbiol. Biotechnol." volume="88" first="1113" last="1123">
            <title>Characterization of endo-1,3-1,4-beta-glucanases in GH family 12 from Magnaporthe oryzae.</title>
            <authorList>
                <person name="Takeda T."/>
                <person name="Takahashi M."/>
                <person name="Nakanishi-Masuno T."/>
                <person name="Nakano Y."/>
                <person name="Saitoh H."/>
                <person name="Hirabuchi A."/>
                <person name="Fujisawa S."/>
                <person name="Terauchi R."/>
            </authorList>
            <dbReference type="PubMed" id="20680265"/>
            <dbReference type="DOI" id="10.1007/s00253-010-2781-2"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>BIOPHYSICOCHEMICAL PROPERTIES</scope>
        <scope>INDUCTION</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Endoglucanase that functions in part to hydrolyze 1,3-1,4-beta-glucan during infection and spore formation. Shows preferential hydrolysis of barley beta-glucan and lichenan, but also hydrolyzes carboxymethylcellulose (CMC) to a slight extent.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="biophysicochemical properties">
        <kinetics>
            <KM evidence="3">1.18 mg/ml for barley beta-glucan (when expressed in M.oryzae)</KM>
        </kinetics>
        <phDependence>
            <text evidence="3">Optimum pH is 6.0-7.5.</text>
        </phDependence>
        <temperatureDependence>
            <text evidence="3">Optimum temperature is 30-40 degrees Celsius.</text>
        </temperatureDependence>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="3">Expression invreases increased 4-5 days after inoculation, but is not detected during spore formation.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyl hydrolase 12 (cellulase H) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716046.1">
        <property type="nucleotide sequence ID" value="XM_003715998.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716047.1">
        <property type="nucleotide sequence ID" value="XM_003715999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5V2"/>
    <dbReference type="SMR" id="G4N5V2"/>
    <dbReference type="STRING" id="242507.G4N5V2"/>
    <dbReference type="CAZy" id="GH12">
        <property type="family name" value="Glycoside Hydrolase Family 12"/>
    </dbReference>
    <dbReference type="GlyCosmos" id="G4N5V2">
        <property type="glycosylation" value="2 sites, No reported glycans"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_08537T0">
        <property type="protein sequence ID" value="MGG_08537T0"/>
        <property type="gene ID" value="MGG_08537"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_08537T1">
        <property type="protein sequence ID" value="MGG_08537T1"/>
        <property type="gene ID" value="MGG_08537"/>
    </dbReference>
    <dbReference type="GeneID" id="2678841"/>
    <dbReference type="KEGG" id="mgr:MGG_08537"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08537"/>
    <dbReference type="eggNOG" id="ENOG502SH4Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051064_0_1_1"/>
    <dbReference type="InParanoid" id="G4N5V2"/>
    <dbReference type="OMA" id="VWPISES"/>
    <dbReference type="OrthoDB" id="89349at2759"/>
    <dbReference type="PHI-base" id="PHI:2978"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002594">
        <property type="entry name" value="GH12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002">
        <property type="entry name" value="BLR1656 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34002:SF10">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01670">
        <property type="entry name" value="Glyco_hydro_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword id="KW-0136">Cellulose degradation</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0326">Glycosidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0624">Polysaccharide degradation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000432717" description="Endoglucanase cel12B" evidence="1">
        <location>
            <begin position="18"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="20680265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="4">
        <source>
            <dbReference type="PubMed" id="20680265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="264" mass="29173" checksum="CCB214C72006C597" modified="2011-12-14" version="1" precursor="true">MLPRLATVLLSALGASASVLPTTTTRDLASRAAPVASLCTQYAYLKTNGYEILNNLWGIDTATGGGSQCTYYNGAVGPAVAFSSDWTWRGNDNTVKSYVYANRVFERRLVGDIKSLPTSVQWSYNTTNVRANVAYDIFTHTDVNHPNSSGDFELMIWLQRYGGIWPITESSTGSPVERVTIAGYTWELFTGWNGAMRVYSFLPPSGTSYNSFSADVKLFFDYLGQKYAFPASEQYMLIYNFGTEAFTGGPAHFDVSRFQAEVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5V3</accession>
    <name>G4N5V3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716048.1">
        <property type="nucleotide sequence ID" value="XM_003716000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5V3"/>
    <dbReference type="GeneID" id="12986492"/>
    <dbReference type="KEGG" id="mgr:MGG_15359"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15359"/>
    <dbReference type="HOGENOM" id="CLU_990701_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5V3"/>
    <dbReference type="OrthoDB" id="417125at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="281" mass="30392" checksum="D3BCC9E6D2AE476B" modified="2011-12-14" version="1">MVRQTTSSGGDTIKAVLLKLSPEFEDLCELRTKVATIRAADAFFDGQAGLNAWQTTRHPERLLLDILGPSIAALDVETDILNIPPSQDGTPPRVLDLTPAPSAFTVAVARRNPNAQISGLVRPGAVADMNEVPEYTNNPRPPHAISEMALHVLGPDAWGRVAPISITDRNRHAGDANGELLLETGACRTGRQPLQQTNIPTIYMQHIQDVVCISEDAVESDSEVARIRDAGMSATDPFQGQRFDFVFASAGGEVGPVRTMGRRHYDRLLRGSPREADEGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N600</accession>
    <name>G4N600_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716895.1">
        <property type="nucleotide sequence ID" value="XM_003716847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N600"/>
    <dbReference type="STRING" id="242507.G4N600"/>
    <dbReference type="GeneID" id="2684789"/>
    <dbReference type="KEGG" id="mgr:MGG_06634"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06634"/>
    <dbReference type="eggNOG" id="ENOG502SDJU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_585354_0_0_1"/>
    <dbReference type="InParanoid" id="G4N600"/>
    <dbReference type="OMA" id="KPFSKCQ"/>
    <dbReference type="OrthoDB" id="2398441at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033768">
        <property type="term" value="C:SUMO-targeted ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038886">
        <property type="entry name" value="E3_SLX5/Rfp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28042">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE COMPLEX SLX5-SLX8 SUBUNIT SLX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28042:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE COMPLEX SLX5-SLX8 SUBUNIT SLX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="437" mass="48517" checksum="8D19B92CFB61BCF4" modified="2011-12-14" version="1">MADDDSDLEILDSLPDHINNDRRSVPPRRRRPANPSEFDSLWDRGPRRTRESARDLPGMNERRRQRLQQDAMQHLSRQSDAARHRPQDVDVIDLTDEPDNVPPAAVPLTLPRVVPDSNGMPARRNVGFLDVVNNPSQQPDHSRNPRRQQSGLARTPSLSRSDPSLSFGRGRSAIPAQMHIDLTEDDDVPSITGPAAGQQARYATRGSMLDPPANRTWHWPRPGGAVHSVLGMFLGLGGNASRNAGAPADAAGGAAGNHRLREIRDIQQELERTMELNQLMQNRPRDMLIELDYGGLPPNFWDDHTPNRPKPAYVPPPDAPVGFTRDTGDEVVAICPGCDEELVYDPDEVRDEPEAVATKKPRTKKDRAEHHFMAIKACGHVYCRVCYERRTTPSSRKGGSGPGPNFRQLQDSTKLLCAVDDCASEIKSKTAWLGIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6C0</accession>
    <name>G4N6C0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716961.1">
        <property type="nucleotide sequence ID" value="XM_003716913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6C0"/>
    <dbReference type="GeneID" id="2684730"/>
    <dbReference type="KEGG" id="mgr:MGG_06575"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06575"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_509051_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6C0"/>
    <dbReference type="OMA" id="ASTETHW"/>
    <dbReference type="OrthoDB" id="21416at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="565"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="614" mass="71250" checksum="8467AF6D4AE9C372" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6G3</accession>
    <name>G4N6G3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin-conjugating enzyme E2 2</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">E2 ubiquitin-conjugating enzyme 11</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">E2 ubiquitin-conjugating enzyme 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ubiquitin carrier protein UBC2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Ubiquitin-protein ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin-protein ligase UBC2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_03728</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="14">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716152.1">
        <property type="nucleotide sequence ID" value="XM_003716104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6G3"/>
    <dbReference type="SMR" id="G4N6G3"/>
    <dbReference type="FunCoup" id="G4N6G3">
        <property type="interactions" value="412"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N6G3"/>
    <dbReference type="GeneID" id="2676704"/>
    <dbReference type="KEGG" id="mgr:MGG_03728"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03728"/>
    <dbReference type="eggNOG" id="KOG0421">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_9_1_1"/>
    <dbReference type="InParanoid" id="G4N6G3"/>
    <dbReference type="OMA" id="PKDNHAV"/>
    <dbReference type="OrthoDB" id="10253686at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23791">
        <property type="entry name" value="UBCc_UBE2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000068">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2-20 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="16">
        <location>
            <begin position="33"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="13">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00080142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA49833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="181" mass="19925" checksum="E90C0F889C9B2607" modified="2011-12-14" version="1">MDFGNMEDAQNSAPGSMQNAKLGMSNKGPDSQSVTKRLQTELMQLMTSPAPGVSAFPSADGNLLSWSATIEGPDDTPYTGLTLKLSFAFPPNYPYSPPTVLFKTPIYHPNVDFSGRICLDILKDKWTAAYNIQTVLLSLQSLLGEPNNASPLNGEAAELWDKDMDEFKRKVLARHRDIDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6S5</accession>
    <name>G4N6S5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anaphase-promoting complex subunit CDC26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716211.1">
        <property type="nucleotide sequence ID" value="XM_003716163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6S5"/>
    <dbReference type="SMR" id="G4N6S5"/>
    <dbReference type="GeneID" id="2676596"/>
    <dbReference type="KEGG" id="mgr:MGG_03674"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03674"/>
    <dbReference type="eggNOG" id="ENOG502T4K1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1482270_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6S5"/>
    <dbReference type="OrthoDB" id="5243363at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018860">
        <property type="entry name" value="APC_suCDC26"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10471">
        <property type="entry name" value="ANAPC_CDC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="19895" checksum="8B99BACA22EBE2B4" modified="2011-12-14" version="1">MLRRAPTVISITAEDVAAYEDRQEHLRQRRRQGSRAAPVLKTATATTITTTTPQQRQQYIQQQQQQQHPYTDDHPNQYASEDEDMDDIVGNDDDVDEEDDTAPPPPPPHARQPRQPRMLSQEQRGGAHRGGAVGAAAATTPTPSHQAGGGRGSSAQQPPAAPGGRVTRSREERIGVGASRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6V1</accession>
    <name>G4N6V1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06519</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717034.1">
        <property type="nucleotide sequence ID" value="XM_003716986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6V1"/>
    <dbReference type="SMR" id="G4N6V1"/>
    <dbReference type="STRING" id="242507.G4N6V1"/>
    <dbReference type="GeneID" id="2684674"/>
    <dbReference type="KEGG" id="mgr:MGG_06519"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06519"/>
    <dbReference type="eggNOG" id="KOG0305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014831_3_0_1"/>
    <dbReference type="InParanoid" id="G4N6V1"/>
    <dbReference type="OMA" id="IPWGPYG"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF5">
        <property type="entry name" value="MEIOSIS-SPECIFIC APC_C ACTIVATOR PROTEIN AMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="148"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="752"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="830" mass="90476" checksum="ED11C8E86C37332D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6Y8</accession>
    <name>G4N6Y8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADP-dependent alcohol dehydrogenase 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06489</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717071.1">
        <property type="nucleotide sequence ID" value="XM_003717023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6Y8"/>
    <dbReference type="SMR" id="G4N6Y8"/>
    <dbReference type="STRING" id="242507.G4N6Y8"/>
    <dbReference type="GeneID" id="2684644"/>
    <dbReference type="KEGG" id="mgr:MGG_06489"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06489"/>
    <dbReference type="eggNOG" id="KOG0023">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_20_2_1"/>
    <dbReference type="InParanoid" id="G4N6Y8"/>
    <dbReference type="OMA" id="EAIFPMV"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="7">
        <location>
            <begin position="35"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="190"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA50752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="360" mass="39230" checksum="012133D62C93C0B9" modified="2011-12-14" version="1">MGYPETFEGFCVDSPKTWNKFSKQELKPKPFEDYDIDVEIAACGVCGSDIHTLTGGWGDFQGPLCVGHEVVGRAVRVGSKVRSEIKEGDRVGVGAQVWACLKCKVCESKNENYCPHMVDTYNAKYEDGSSAHGGYASHIRAHEYFTFKIPDGLETEIAAPLLCAGITVYSPLFRAGVGPGKKVAVVGIGGLGHLGVQFSKALGAETYAITHSKNKVEDAKKLGAKEVIVSSDKDWHKPYAFTFDFILNAADALDQFDLPAYMSTLNIEGQFHTVGISDKPVPQLTAFAFAPNAAKLTGSHLGNHQEMDAMLKLAAEKNVKPWVETIDVSEEGCKKAVEGVKDNKVRYRYTLTGFDKAFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N709</accession>
    <name>G4N709_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716241.1">
        <property type="nucleotide sequence ID" value="XM_003716193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N709"/>
    <dbReference type="STRING" id="242507.G4N709"/>
    <dbReference type="GeneID" id="12984385"/>
    <dbReference type="KEGG" id="mgr:MGG_17053"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17053"/>
    <dbReference type="eggNOG" id="ENOG502SE67">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050915_2_0_1"/>
    <dbReference type="InParanoid" id="G4N709"/>
    <dbReference type="OMA" id="CNDPSHQ"/>
    <dbReference type="OrthoDB" id="5296155at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="43624" checksum="CC6AD8CEDCBD1527" modified="2011-12-14" version="1">MFPHRIVTTLPSLLPIIHENEEVVPPAIPRLVAPTIPPPSYRRGGAEVDGLWFDGNAFAAVADYLNNQEQGLLSSPGYARSFYTSKSDYGGVAMDQTLPARPYEDYDDDEPPRVRFLDRWGWRKVVFATVGFILFLLVLGLGTGYGLRNSGPTIAGQQGEGQSPGNLPSASPTAAPRPSQSAQPSPPANTNPKPKQRFPAGTYSFTAALMSVQTSCTSDPAVFGCYPFTTYGSATVSQSAATFEWTIESTGSSSYQLSSAAGSVSNATLLPQFSNLPMTLVEANTDTERYTFNLTIAKEYVVPNGTATVLPGTADCWYNSTVVKVELWTRQRATYPPSITDVPLPNTDGTGSTTTAVSPWPYRFTMSQVQGSSPNVPECRNSQGTVLGPTINGAGDCQCSYKNYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8P8</accession>
    <name>G4N8P8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717363.1">
        <property type="nucleotide sequence ID" value="XM_003717315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8P8"/>
    <dbReference type="GeneID" id="12986501"/>
    <dbReference type="KEGG" id="mgr:MGG_17207"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17207"/>
    <dbReference type="HOGENOM" id="CLU_2812901_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8P8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="67" mass="7147" checksum="503F99FB8BF445E2" modified="2011-12-14" version="1">MVSIPEGSVPAGLADTSWSIDSDAPQLPGEADLAVKLRFEKRLVAGEDHKMVELSWRLSIRGVCPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N901</accession>
    <name>G4N901_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fucose-specific lectin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_13584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    <accession>G4N9C2</accession>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="KEGG" id="mgr:MGG_13607"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13607"/>
    <dbReference type="eggNOG" id="ENOG502RS1M">
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="3927" mass="376665" checksum="F6A1AC456C1024DF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9D9</accession>
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        <submittedName>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717499.1">
        <property type="nucleotide sequence ID" value="XM_003717451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9D9"/>
    <dbReference type="GeneID" id="2681030"/>
    <dbReference type="KEGG" id="mgr:MGG_10007"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10007"/>
    <dbReference type="HOGENOM" id="CLU_2237129_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9D9"/>
    <dbReference type="OrthoDB" id="5230233at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="105" mass="11507" checksum="2172F701C1FAD033" modified="2011-12-14" version="1">MATGAPNAATEPLLNSQQRSGLASIHQSLNNARTQVSLLLDQVTNIAIKRMLTEVADDLDVVISSVGNIEADATHPEKRVRVYDPRDVEFQAAQAKLREQEKGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9L0</accession>
    <name>G4N9L0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717517.1">
        <property type="nucleotide sequence ID" value="XM_003717469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9L0"/>
    <dbReference type="GeneID" id="12986556"/>
    <dbReference type="KEGG" id="mgr:MGG_17252"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17252"/>
    <dbReference type="eggNOG" id="ENOG502T33N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_526824_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9L0"/>
    <dbReference type="OMA" id="LWIDEES"/>
    <dbReference type="OrthoDB" id="2571985at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="57941" checksum="57B17D8D740F5B6C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9M2</accession>
    <name>G4N9M2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_09986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717529.1">
        <property type="nucleotide sequence ID" value="XM_003717481.1"/>
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    <dbReference type="AlphaFoldDB" id="G4N9M2"/>
    <dbReference type="GeneID" id="2681009"/>
    <dbReference type="KEGG" id="mgr:MGG_09986"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09986"/>
    <dbReference type="eggNOG" id="ENOG502RNDT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1294482_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9M2"/>
    <dbReference type="OrthoDB" id="2867594at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="171" mass="18768" checksum="DF3AECE7D5C59490" modified="2011-12-14" version="1">MDDKEEAQGPVIPVFCTARIPIKTLERFIQCNSAYETSESFRARFITGTSRDDVAIIDGVPEESFSSPCIGKTLQDVTNFWKENVDGLEGFASSVFILLDEHSEASLTCLAVAIDYTLEEGDDEAAAPVDVLKADFYVARGVLQLVALGVQSLHENRDPAVVLTRENFAMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9R8</accession>
    <name>G4N9R8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAM86A protein</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_10684</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003715894.1">
        <property type="nucleotide sequence ID" value="XM_003715846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9R8"/>
    <dbReference type="SMR" id="G4N9R8"/>
    <dbReference type="FunCoup" id="G4N9R8">
        <property type="interactions" value="509"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9R8"/>
    <dbReference type="GeneID" id="2682885"/>
    <dbReference type="KEGG" id="mgr:MGG_10684"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10684"/>
    <dbReference type="eggNOG" id="KOG2497">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038942_1_2_1"/>
    <dbReference type="InParanoid" id="G4N9R8"/>
    <dbReference type="OMA" id="PIRTYRI"/>
    <dbReference type="OrthoDB" id="194386at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="37216" checksum="810F08364085B302" modified="2011-12-14" version="1">MSDLDRFCWQYLQLEQRLDYPPRELIRTEECQSQLFARLFAPGALPHPPPHRYQLRVLKELIGRIEASIEDWDEHGISDDLATALTALMSQPTPSEATAAQQKSYVTYHLSLLDQPSSSSSSKSITLLENRHLIAASGTTGLRTWEAALHLGQYLCLHADSLVSGRRVLELGAGTGYLSMLCAAHLGAAHVVASDGSDDVVANLPEGAFLNGLQHEGQAAAAAAERAAVQPMDLKWGHALVGTEDARWNGGEPVHLVLGADVTYDATLAAPLLGTIAELVGMFPDVQVLIAATERNSATYAAFLDAVAKSADVALLEEVALAVDGSRGPFFPDNVPIHICRLGRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA72</accession>
    <name>G4NA72_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715941.1">
        <property type="nucleotide sequence ID" value="XM_003715893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA72"/>
    <dbReference type="GeneID" id="2678833"/>
    <dbReference type="KEGG" id="mgr:MGG_08441"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08441"/>
    <dbReference type="HOGENOM" id="CLU_1299935_0_0_1"/>
    <dbReference type="InParanoid" id="G4NA72"/>
    <dbReference type="OMA" id="CQAYKAR"/>
    <dbReference type="OrthoDB" id="10582254at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465961" evidence="2">
        <location>
            <begin position="18"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="212" mass="20782" checksum="7AB8E73E419979BE" modified="2011-12-14" version="1">MRFQAVVIALFAAGVTARPMSGVMGMMSSLLSSSGSSSSSSQSPSSTGCSDICAKVTQALGPSNGQMAMPVCNGLCQAYKARKGAKNPNYGGQMSPSGSNYNTQMPTQASGLNSQMGGGQSSDFNSPMGGGQEADYGGSMGQGQSSGYGGSMGQGQSSGYGGSMGQGQSSGYGGSMGQGQSSGYGGSMGQGQESAYGRQSSSPGGYGSGGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAK9</accession>
    <name>G4NAK9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_17284</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717666.1">
        <property type="nucleotide sequence ID" value="XM_003717618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAK9"/>
    <dbReference type="GeneID" id="12986595"/>
    <dbReference type="KEGG" id="mgr:MGG_17284"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17284"/>
    <dbReference type="eggNOG" id="ENOG502SZCW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019059_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAK9"/>
    <dbReference type="OMA" id="QILFRIQ"/>
    <dbReference type="OrthoDB" id="4847360at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032567">
        <property type="entry name" value="RTL1-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503">
        <property type="entry name" value="LDOC1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503:SF22">
        <property type="entry name" value="TRANSPOSON TY3-I GAG POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="355" mass="40739" checksum="659B9547D2D09559" modified="2011-12-14" version="1">MSSQSSKNNTPSTPATSSKAAQKAPVRPKDDSDSEDEEDQLRRQVARTNQELHEQTLRATQLQEELQALRASANVTSTPLDGRERLKLNPPATFDGTPGQLKGYLVQVRTYQAFHLETFRSETEKVVHAATFLRGRALSWFEPLLQEWLDVPPEERRQEVTDIFSTFAGYERTLRSLFQEPDEKRQTERDLANLRQTKSASAYAAEFRRLATRLDMTEETKILQFYQGLKSEIKDEVSKLDRPEDFLDGPMDLSATQHKKPRKDPKNGKCFKCDKTGHIARNCPRNQEDIPDFRGKTEKPRGLNATNYQQLRPNQHSTMSWTTCYDDNCMTHNSSKIDAGWYPQKPRGTRTLAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCE9</accession>
    <name>G4NCE9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_00394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718682.1">
        <property type="nucleotide sequence ID" value="XM_003718634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCE9"/>
    <dbReference type="GeneID" id="2674113"/>
    <dbReference type="KEGG" id="mgr:MGG_00394"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00394"/>
    <dbReference type="eggNOG" id="ENOG502T5QY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_839579_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCE9"/>
    <dbReference type="OMA" id="PETCEEH"/>
    <dbReference type="OrthoDB" id="2142213at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="328" mass="35426" checksum="66B40DDC4E340BDB" modified="2011-12-14" version="1">MPRMHLLARAGIAAAILSNVTVAYTILPTTDAAGARTYDLDARKFELQGPYSKPDIHDAGFDVAAELLKVLPAHQPINISRWEAGVLPSNCLKYFGSDGRQVTRGDFTVYNHVDSDTSIEKMTTAFGHLPIGMREHVRTVAALPHPPPGERAAAFSIDGDIAVRPRYWDMHTLSHEVSHIIDSKLPTAQGHNPYTGRPAALARRYGWRPAPKPYDAAAAAAAAQHLPGTGGKYSDSLRWRGAEKGDERVVSRYALTSWAEHFAETAGVGLLEVFGGAGTVDRLSPAAGRGLKGQVGMWVRDWGRVVGGGPETCEEHVRPAQPEFVIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCF4</accession>
    <name>G4NCF4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718687.1">
        <property type="nucleotide sequence ID" value="XM_003718639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCF4"/>
    <dbReference type="GeneID" id="2674706"/>
    <dbReference type="KEGG" id="mgr:MGG_00389"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00389"/>
    <dbReference type="HOGENOM" id="CLU_1806557_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCF4"/>
    <dbReference type="OrthoDB" id="10604414at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="143" mass="15505" checksum="EC68EC8374EB8B76" modified="2011-12-14" version="1">MGCCCSKTSKAPRPQPGPQSYHAPASWRPEHEKKPTNKGPAPGTRVAPLPRPPGDVRYKYTADGTPWPQAMEAYRIGVRSGGRPDTESSLSPRQLPSPQPPSSGSPTTPSSTGTVVRKKNSEAPLRAEGKKRDPRQNRSDPYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCH7</accession>
    <name>G4NCH7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_01080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717858.1">
        <property type="nucleotide sequence ID" value="XM_003717810.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NCH7"/>
    <dbReference type="STRING" id="242507.G4NCH7"/>
    <dbReference type="GeneID" id="2674689"/>
    <dbReference type="KEGG" id="mgr:MGG_01080"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01080"/>
    <dbReference type="eggNOG" id="ENOG502STGS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002208_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCH7"/>
    <dbReference type="OMA" id="IIWDPLA"/>
    <dbReference type="OrthoDB" id="436852at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="69"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        <source>
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        <source>
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</entry>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Priest M."/>
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                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
        </source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA49130.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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</entry>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA49173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="2675032"/>
    <dbReference type="KEGG" id="mgr:MGG_00329"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00329"/>
    <dbReference type="eggNOG" id="ENOG502SHAW">
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    <dbReference type="PHI-base" id="PHI:5621"/>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="entry name" value="XnlR_reg_dom"/>
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        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
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    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
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    </dbReference>
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        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
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        <property type="entry name" value="Fungal_trans"/>
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        <property type="entry name" value="Zn_clus"/>
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    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
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        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
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        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
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    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50048"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA49173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="708" mass="77613" checksum="FEDBBFE15081CF62" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDM2</accession>
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    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrophobin</fullName>
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            <taxon>Sordariomycetes</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718891.1">
        <property type="nucleotide sequence ID" value="XM_003718843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDM2"/>
    <dbReference type="GeneID" id="2674315"/>
    <dbReference type="KEGG" id="mgr:MGG_00216"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00216"/>
    <dbReference type="HOGENOM" id="CLU_1907117_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDM2"/>
    <dbReference type="OrthoDB" id="10567287at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466138" description="Hydrophobin" evidence="1">
        <location>
            <begin position="21"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="13064" checksum="2768BDA25758224F" modified="2011-12-14" version="1">MQFATLAALFALSSSHAATAQFLGGLFPCGFSPCGIVVAGPGSNPPMSVRSADCSSFLLATVPSTTVTSTVAPPTTTTTPSISTLLTSTKALPTYGIICGAAGYRSACSCMGISASTTTSGSTVTTITATPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDN5</accession>
    <name>G4NDN5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718057.1">
        <property type="nucleotide sequence ID" value="XM_003718009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDN5"/>
    <dbReference type="STRING" id="242507.G4NDN5"/>
    <dbReference type="GeneID" id="12984007"/>
    <dbReference type="KEGG" id="mgr:MGG_17344"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17344"/>
    <dbReference type="eggNOG" id="ENOG502RXI4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1731861_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDN5"/>
    <dbReference type="OrthoDB" id="2536795at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018554">
        <property type="entry name" value="FRQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09421">
        <property type="entry name" value="FRQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="151" mass="16290" checksum="F71829CD01D0B8E0" modified="2011-12-14" version="1">MIEYKTVRLNRLDPVELPPAASFVPPFSTSSSDSDIDESDLLESEEGQDAELYSAYPEGQDLSQSDEEDEAESDDVGILQIGGTGNSKNKPGKKVSVNRQQGLDMHLRSGLVRRPQTDISNGPSKQPDARTQSSVATAGRAESGYNSSLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEB2</accession>
    <name>G4NEB2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kynurenine 3-monooxygenase</fullName>
            <ecNumber evidence="10">1.14.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Biosynthesis of nicotinic acid protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Kynurenine 3-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">BNA4</name>
        <name evidence="13" type="ORF">MGG_00805</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-kynurenine + NADPH + O2 + H(+) = 3-hydroxy-L-kynurenine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:20545"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the aromatic-ring hydroxylase family. KMO subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.9" evidence="10"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718179.1">
        <property type="nucleotide sequence ID" value="XM_003718131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEB2"/>
    <dbReference type="SMR" id="G4NEB2"/>
    <dbReference type="FunCoup" id="G4NEB2">
        <property type="interactions" value="760"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NEB2"/>
    <dbReference type="GeneID" id="2675223"/>
    <dbReference type="KEGG" id="mgr:MGG_00805"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00805"/>
    <dbReference type="eggNOG" id="KOG2614">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023210_2_1_1"/>
    <dbReference type="InParanoid" id="G4NEB2"/>
    <dbReference type="OMA" id="REFMFIA"/>
    <dbReference type="OrthoDB" id="10053569at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004502">
        <property type="term" value="F:kynurenine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070189">
        <property type="term" value="P:kynurenine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:L-tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01971">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027545">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028:SF2">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0274">FAD</keyword>
    <keyword evidence="2 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 10" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8 10 13" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0521">NADP</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 10" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
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        <location>
            <begin position="6"/>
            <end position="363"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA48595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="528" mass="59275" checksum="F34ACFD3A2860EAE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NED1</accession>
    <name>G4NED1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactamase_B domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718198.1">
        <property type="nucleotide sequence ID" value="XM_003718150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NED1"/>
    <dbReference type="SMR" id="G4NED1"/>
    <dbReference type="GeneID" id="2674338"/>
    <dbReference type="KEGG" id="mgr:MGG_00791"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00791"/>
    <dbReference type="eggNOG" id="ENOG502QU66">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051050_0_1_1"/>
    <dbReference type="InParanoid" id="G4NED1"/>
    <dbReference type="OMA" id="DCILLSH"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050114">
        <property type="entry name" value="UPF0173_UPF0282_UlaG_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546:SF7">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43546">
        <property type="entry name" value="UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="74"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="358" mass="39647" checksum="BBFE6D67DE516452" modified="2011-12-14" version="1">MSPTNQITLNPARREDLLRGGAKKQQQQQQQEKAAKLPLGKQHTHPRGSSTGDEDGSVSFVGTATTILEWQGVRILTDPNFLHAGDHVHLGPGVSARRRTDPAVELEALPPLDAILLSHYHEDHFDRLVEDSLNRDFTIVTTPHARSCLAAGGAEDEPFRRVWGLDLFQDLLLDIDDASSSAAGERHRRPAIKVTGMPGRHVPPGVLSAANEVLQAVPPTNGWMLELGYRPSAGDGDEGAMETGYRIYISGDTLMVDDLKKIPEWLGDKRIDLMLVHLGGTTIPGPSLPLLMVTMDAEQGLQLMRLLDPEITIPIHYDDYDVFLSPLEDFKKEVDGQGKRDRVVYLDRGEHYRFKVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEK2</accession>
    <name>G4NEK2_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">Hyaluronan/mRNA-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718216.1">
        <property type="nucleotide sequence ID" value="XM_003718168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEK2"/>
    <dbReference type="GeneID" id="2674320"/>
    <dbReference type="KEGG" id="mgr:MGG_00777"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00777"/>
    <dbReference type="eggNOG" id="ENOG502SD5D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1049994_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEK2"/>
    <dbReference type="OrthoDB" id="2122308at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29296" checksum="AFF7D600F8D6ADE1" modified="2011-12-14" version="1">MHWLGHAAGVWGITWADPSRFWPRYSRYTVSSVSRCFQGSRTLFPVVINTYAWQQHASSVKVTGTRAAIPGTVGINKLVVSKVYNGMELRGQGNAMSRTTSYDPSTIHHQPSSLVPNKTHSTLPNSSIPIMTRSHKANNRNHAALANGTALPEEHIPKYFAKHGFLDNEPKKVKKNGGGRSNWGNAGEEVLDENFTFAHARRRSNSSSYTSGQYDFKTKFDVNEPEPVFEESMGAEFDEEETLAKTDTSSSNGSVNGEDKMAKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEX3</accession>
    <name>G4NEX3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Hydantoinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_00722</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718283.1">
        <property type="nucleotide sequence ID" value="XM_003718235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEX3"/>
    <dbReference type="SMR" id="G4NEX3"/>
    <dbReference type="GeneID" id="2674967"/>
    <dbReference type="KEGG" id="mgr:MGG_00722"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00722"/>
    <dbReference type="eggNOG" id="ENOG502SJ4Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007154_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEX3"/>
    <dbReference type="OMA" id="GCNIDGT"/>
    <dbReference type="OrthoDB" id="5404895at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.390.10">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1610.10">
        <property type="entry name" value="CV3147-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048350">
        <property type="entry name" value="S-Me-THD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024071">
        <property type="entry name" value="S-Me-THD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010318">
        <property type="entry name" value="S-Me-THD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027479">
        <property type="entry name" value="S-Me-THD_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF10">
        <property type="entry name" value="HYDANTOINASE_OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20906">
        <property type="entry name" value="S-Me-THD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="S-Me-THD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160991">
        <property type="entry name" value="CV3147-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase/oxoprolinase N-terminal" evidence="3">
        <location>
            <begin position="38"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="2">
        <location>
            <begin position="193"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD N-terminal" evidence="4">
        <location>
            <begin position="587"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="S-Me-THD-like C-terminal" evidence="5">
        <location>
            <begin position="755"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA48699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="990" mass="103330" checksum="64D8860967B725D7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGB8</accession>
    <name>G4NGB8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719442.1">
        <property type="nucleotide sequence ID" value="XM_003719394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGB8"/>
    <dbReference type="GeneID" id="2682037"/>
    <dbReference type="KEGG" id="mgr:MGG_10425"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10425"/>
    <dbReference type="HOGENOM" id="CLU_1332156_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGB8"/>
    <dbReference type="OrthoDB" id="5240356at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466931" evidence="2">
        <location>
            <begin position="22"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="206" mass="20848" checksum="8A0EE8DB86392FE7" modified="2011-12-14" version="1">MHPQTFFTAALGLMAASTALATPISHGSQVATISTRSPEPLSLDDIINGVKKGVDKLKEKFGGGKKDPAPAPAPTPDAPASNSTLRVRMTKRTPEPLGIDDVINGVKAGVDLIKSLKGGDNAGNGDASQSKLSQIIAKIKSGMDSLKNLFKGGKKGGDGAATPAPAPTPGGNKTTPTPTPAPGAGGSKGNSTVRAVLRKRVVYLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH93</accession>
    <name>G4NH93_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Aquaporin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_03904</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O(in) = H2O(out)</text>
            <dbReference type="Rhea" id="RHEA:29667"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719970.1">
        <property type="nucleotide sequence ID" value="XM_003719922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH93"/>
    <dbReference type="SMR" id="G4NH93"/>
    <dbReference type="FunCoup" id="G4NH93">
        <property type="interactions" value="255"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NH93"/>
    <dbReference type="GeneID" id="2677198"/>
    <dbReference type="KEGG" id="mgr:MGG_03904"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03904"/>
    <dbReference type="eggNOG" id="KOG0223">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020019_1_4_1"/>
    <dbReference type="InParanoid" id="G4NH93"/>
    <dbReference type="OMA" id="RAFLYWI"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1080.10:FF:000014">
        <property type="entry name" value="Aquaporin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF283">
        <property type="entry name" value="AQUAPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="287" mass="31623" checksum="012E31A3AE37B835" modified="2011-12-14" version="1">MAGPQPFMRFGPTSNASHYGPDSQAPRINWKDLSREERTEVLRLPWTQWMNSNVKNHFVAMLGELIGTTMFLFFAFAGVEVANIGLPSSAPFNLAKQLYISLSFGFSLMVNVWIFFRISGAQFNPAVTLALWMTGAVDAVRGVCLVISQLCGGMLASVIVRFLFPQRFSVRTSLSQNTSLVQGVFIEALLTSELVFTILMLAKEKHKATYMAPVGIGLALWIDHMVGVPFTGAGINPARSFGPCVVTATFEPEHWIYWVGPGIGALIAVAFYKLIKVLEYESLQNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHZ2</accession>
    <name>G4NHZ2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF3433 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720219.1">
        <property type="nucleotide sequence ID" value="XM_003720171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHZ2"/>
    <dbReference type="GeneID" id="2680373"/>
    <dbReference type="KEGG" id="mgr:MGG_09392"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09392"/>
    <dbReference type="eggNOG" id="ENOG502QQ7D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003000_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHZ2"/>
    <dbReference type="OMA" id="RINDNWH"/>
    <dbReference type="OrthoDB" id="5332281at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021840">
        <property type="entry name" value="DUF3433"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37544">
        <property type="entry name" value="SPRAY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11915">
        <property type="entry name" value="DUF3433"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="686"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="811"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="851"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="918"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="968"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1105" mass="120349" checksum="0816CA84B6902AF4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIB4</accession>
    <name>G4NIB4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptide hydrolase</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_14292</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720341.1">
        <property type="nucleotide sequence ID" value="XM_003720293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIB4"/>
    <dbReference type="SMR" id="G4NIB4"/>
    <dbReference type="STRING" id="242507.G4NIB4"/>
    <dbReference type="GeneID" id="2682907"/>
    <dbReference type="KEGG" id="mgr:MGG_14292"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14292"/>
    <dbReference type="eggNOG" id="KOG2195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024336_0_2_1"/>
    <dbReference type="InParanoid" id="G4NIB4"/>
    <dbReference type="OMA" id="AHFQQTQ"/>
    <dbReference type="OrthoDB" id="10013407at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04816">
        <property type="entry name" value="PA_SaNapH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF26">
        <property type="entry name" value="PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="178"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="9">
        <location>
            <begin position="297"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA47974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="551" mass="58730" checksum="CD0D6CA884054BA0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIK7</accession>
    <name>G4NIK7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_09807</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720434.1">
        <property type="nucleotide sequence ID" value="XM_003720386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIK7"/>
    <dbReference type="STRING" id="242507.G4NIK7"/>
    <dbReference type="GeneID" id="2680798"/>
    <dbReference type="KEGG" id="mgr:MGG_09807"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09807"/>
    <dbReference type="HOGENOM" id="CLU_1315611_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIK7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF30">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="116"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="176"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA48067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="22041" checksum="72826B51CCC0859A" modified="2011-12-14" version="1">MLHQSSASSVVPSTSSASAPLSSSQSKEANTNGASASTDSSSTTTLAAPSTATTTATVGEDAAASRQRATGSESDAETLALKVGLGIGIPFAAAIAAFAVWCCFWQRRRKSTKAAEMTQQRQQQQQQQMLPTSNYSLMPGSSSLEKDSPIAHYQGMSPSPQSTLYSAGAPKEFYVNPRFHHGGSELQGSHDLSPRELQGSTWPQNTQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJI4</accession>
    <name>G4NJI4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">5-Methylcytosine G/T mismatch-specific DNA glycosylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02644</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
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        <property type="entry name" value="MeCP2/MBD4"/>
    </dbReference>
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        <property type="entry name" value="5-METHYLCYTOSINE G_T MISMATCH-SPECIFIC DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="METHYL-CPG-BINDING PROTEIN"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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            <begin position="1"/>
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    <feature type="compositionally biased region" description="Basic residues" evidence="3">
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            <begin position="954"/>
            <end position="964"/>
        </location>
    </feature>
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        <source>
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        <source>
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        <source>
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    </evidence>
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            <dbReference type="EMBL" id="EHA46400.1"/>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_09649"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="17357" checksum="1BADFFB8352F85E7" modified="2011-12-14" version="1">MATATNGIPVLCTGQSERVGQPVATALLPELSVVHFTLVEHVDKEMPLLLKGERPSPLNNSVVTPGKWEPGSNPPAAVLLGGAYTDEMVRALRASAGYGPDDDGAATTASSPAGRKIPWIKIDSAKSTLGPRDPGYPADVVRRLKGAVLKLQAEGKLDGVHGGLYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G5EGW2</accession>
    <name>G5EGW2_PYRO7</name>
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        <recommendedName>
            <fullName evidence="12">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
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        <name evidence="14" type="ORF">MGCH7_ch7g866</name>
        <name evidence="15" type="ORF">MGG_03065</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15</strain>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">70-15</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 12">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Vacuole membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
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        <property type="protein sequence ID" value="EAQ71459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="EHA45868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003720563.1"/>
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    <dbReference type="AlphaFoldDB" id="G5EGW2"/>
    <dbReference type="SMR" id="G5EGW2"/>
    <dbReference type="FunCoup" id="G5EGW2">
        <property type="interactions" value="150"/>
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    <dbReference type="STRING" id="242507.G5EGW2"/>
    <dbReference type="GeneID" id="2682618"/>
    <dbReference type="KEGG" id="mgr:MGG_03065"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03065"/>
    <dbReference type="eggNOG" id="KOG0232">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_085752_1_1_1"/>
    <dbReference type="OMA" id="MSVCPPY"/>
    <dbReference type="OrthoDB" id="1744869at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000003">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="4 12" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="13">
        <location>
            <begin position="23"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="13">
        <location>
            <begin position="103"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EAQ71459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA45868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="168" mass="17213" checksum="046762F9E017667F" modified="2011-12-14" version="1">MPGVVPDDSELAPKFAPFVGMAGIAAAMIFGCAGAAFGTAKSGIGIAGVGTFRPDLIMKCLIPVIMSGIIAVYALVVAVLIAQDLNAPTAGTSYDLFRGIMHLACGLSVGLTGLAAGYCIGIVGDKGVRAYMEQSRIFVGMVLILIFGEVLGLYGLIVALILNTRSQE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2013-09-18" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>P0CT12</accession>
    <accession>A4QRI0</accession>
    <accession>G4N7F5</accession>
    <accession>Q5G578</accession>
    <name>H2A_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">HTA1</name>
        <name type="ORF">MGG_03577</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text>Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text>The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text>The [ST]-Q motif constitutes a recognition sequence for kinases from the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Phosphorylated to form H2AS128ph (gamma-H2A) in response to DNA double-strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks. Phosphorylation is dependent on the DNA damage checkpoint kinases MEC1/ATR and TEL1/ATM, spreads on either side of a detected DSB site and may mark the surrounding chromatin for recruitment of proteins required for DNA damage signaling and repair. Gamma-H2A is removed from the DNA prior to the strand invasion-primer extension step of the repair process and subsequently dephosphorylated. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Acetylated by ESA1 to form H2AK4ac and H2AK7ac.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">In contrast to vertebrates and insects, its C-terminus is not monoubiquitinated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H2AK4ac = acetylated Lys-6; H2AK7ac = acetylated Lys-10; H2AS128ph = phosphorylated Ser-133.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716333.1">
        <property type="nucleotide sequence ID" value="XM_003716285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P0CT12"/>
    <dbReference type="SMR" id="P0CT12"/>
    <dbReference type="FunCoup" id="P0CT12">
        <property type="interactions" value="957"/>
    </dbReference>
    <dbReference type="STRING" id="242507.P0CT12"/>
    <dbReference type="EnsemblFungi" id="MGG_03577T0">
        <property type="protein sequence ID" value="MGG_03577T0"/>
        <property type="gene ID" value="MGG_03577"/>
    </dbReference>
    <dbReference type="GeneID" id="2676728"/>
    <dbReference type="KEGG" id="mgr:MGG_03577"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03577"/>
    <dbReference type="eggNOG" id="KOG1756">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062828_3_1_1"/>
    <dbReference type="InParanoid" id="P0CT12"/>
    <dbReference type="OMA" id="CALESQH"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000008">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0007">Acetylation</keyword>
    <keyword id="KW-0158">Chromosome</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-0544">Nucleosome core</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="initiator methionine" description="Removed" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000228732" description="Histone H2A">
        <location>
            <begin position="2"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="[ST]-Q motif">
        <location>
            <begin position="133"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="site" description="Not ubiquitinated" evidence="3">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="1">
        <location>
            <position position="6"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="1">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="1">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="136" mass="14300" checksum="333491E78B9912A4" modified="2013-09-18" version="1">MTGGGKSGGKASGSKNAQSRSSKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKTGKTAGGKNASQEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2006-03-07" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>Q2KES4</accession>
    <accession>A4RAP1</accession>
    <name>Q2KES4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome b2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGCH7_ch7g962</name>
        <name evidence="9" type="ORF">MGG_09162</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15</strain>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">70-15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="KYQ30443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_016990469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q2KES4"/>
    <dbReference type="SMR" id="Q2KES4"/>
    <dbReference type="STRING" id="242507.Q2KES4"/>
    <dbReference type="GeneID" id="2680117"/>
    <dbReference type="KEGG" id="mgr:MGG_09162"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09162"/>
    <dbReference type="eggNOG" id="KOG0538">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020639_1_0_1"/>
    <dbReference type="OMA" id="YNRYRFK"/>
    <dbReference type="OrthoDB" id="1925334at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02922">
        <property type="entry name" value="FCB2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037458">
        <property type="entry name" value="L-MDH/L-LDH_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF140">
        <property type="entry name" value="FMN HYDROXY ACID DEHYDROGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011098170" evidence="6">
        <location>
            <begin position="17"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="7">
        <location>
            <begin position="41"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="122"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="306"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="329"/>
            <end position="330"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EAQ71555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KYQ30443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="383" mass="42055" checksum="56B7650BDCCD40C7" modified="2006-03-07" version="1">MRSAIIVSALASVATAARPYLNEPDTGIDEVLGQLPVGSLPNVTDMHALHDFEWAARRYLPKVNYTYYRNGAGGEWSYRNNLEVYNRYKLRPKTMVDITNIAESMPTTILGHNFSAPFFICPCARAGYGHPDAELNLVQGAGAGKILYIPSSFSTLPIEQIAAKRAPDQILFSQVYTNDNDTANQILFDRAEKAGSKALVWAIDAPGSPSRQRAARYGVGSANAVFITNTWEVLDKFRTMTKLPFILKGIQTVEDAKLAVQHKVPAIILSNHGGRNLDGSPSSLEIALEIHREAPEIFEQIEVLADGGVRYGTDALRLLALGVKAVGIGRPMMYSNVFGVDGVKRAVEIFRNELTNDAANLGVADIKKIDTSFVDWTPNHWYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4F8</accession>
    <name>A0A151V4F8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="KYQ30460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="KEGG" id="mgr:MGG_15046"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15046"/>
    <dbReference type="InParanoid" id="A0A151V4F8"/>
    <dbReference type="Proteomes" id="UP000009058">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007589983" evidence="1">
        <location>
            <begin position="20"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KYQ30460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="167" mass="18903" checksum="09102FE333F48233" modified="2016-06-08" version="1">MVTFTQLFTTFLSVTAVAAVTTHYPAKDRVMIFLSRSDEQPVHARMRLHDLETYVMTDPDFGWKATGYDVLENQGNWAWLISSKHNGNIELAKKLLKLRNYWDETYGWGQNPDGSSMYVATAFKPTTKLPANTQLLRQQAVTNAVLSGWQQAAVARIEDYGKEIGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4P2</accession>
    <name>A0A151V4P2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_18126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165178">
        <property type="protein sequence ID" value="KYQ30552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846056.1">
        <property type="nucleotide sequence ID" value="XM_016990587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4P2"/>
    <dbReference type="GeneID" id="27922210"/>
    <dbReference type="KEGG" id="mgr:MGG_18126"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18126"/>
    <dbReference type="InParanoid" id="A0A151V4P2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KYQ30552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="131" mass="14334" checksum="C985BB21308383A8" modified="2016-06-08" version="1">MTSSKTLADQAAYSTGRQPRIPPPRVEIWAAYPIVSPADAQWAVWKCLADASLSQAQLLMVKGLTDSVWSGTRCWRSTRGEIGASSPHGHSNFSVGLCTVWCGFLREPMPVLAVDCSRGCLQGFGSHLRRW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2025-06-18" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>A4RJH4</accession>
    <accession>G4MW74</accession>
    <name>NM111_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Pro-apoptotic serine protease NMA111</fullName>
            <ecNumber>3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">NMA111</name>
        <name type="ORF">MGG_01824</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Nuclear serine protease which mediates apoptosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="sequence caution" evidence="4">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="EHA55034" version="1"/>
        </conflict>
        <text>Extended N-terminus.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55034.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714841.1">
        <property type="nucleotide sequence ID" value="XM_003714793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RJH4"/>
    <dbReference type="SMR" id="A4RJH4"/>
    <dbReference type="FunCoup" id="A4RJH4">
        <property type="interactions" value="138"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RJH4"/>
    <dbReference type="GeneID" id="2679201"/>
    <dbReference type="KEGG" id="mgr:MGG_01824"/>
    <dbReference type="eggNOG" id="KOG1421">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A4RJH4"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06786">
        <property type="entry name" value="cpPDZ1_ScNma111-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06719">
        <property type="entry name" value="PDZ2-4_Nma111p-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025926">
        <property type="entry name" value="PDZ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366:SF8">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12812">
        <property type="entry name" value="PDZ_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0053">Apoptosis</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0720">Serine protease</keyword>
    <feature type="chain" id="PRO_0000320355" description="Pro-apoptotic serine protease NMA111">
        <location>
            <begin position="1"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ 1">
        <location>
            <begin position="307"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ 2">
        <location>
            <begin position="845"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine protease">
        <location>
            <begin position="84"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="997"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1010"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="1029" mass="113492" checksum="3701A231559C249D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKH6</accession>
    <name>G4MKH6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710177.1">
        <property type="nucleotide sequence ID" value="XM_003710129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKH6"/>
    <dbReference type="SMR" id="G4MKH6"/>
    <dbReference type="GeneID" id="2676145"/>
    <dbReference type="KEGG" id="mgr:MGG_05340"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05340"/>
    <dbReference type="eggNOG" id="ENOG502SG6V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025630_2_0_1"/>
    <dbReference type="InParanoid" id="G4MKH6"/>
    <dbReference type="OMA" id="YHYANSR"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023:SF6">
        <property type="entry name" value="LIPASE CLASS 3 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46023">
        <property type="entry name" value="LIPASE CLASS 3 PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="391"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="582"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="603"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="693" mass="74537" checksum="3E5A4E196346A01A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKH9</accession>
    <name>G4MKH9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">C6 zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_05343</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710180.1">
        <property type="nucleotide sequence ID" value="XM_003710132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKH9"/>
    <dbReference type="FunCoup" id="G4MKH9">
        <property type="interactions" value="498"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKH9"/>
    <dbReference type="GeneID" id="2676148"/>
    <dbReference type="KEGG" id="mgr:MGG_05343"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05343"/>
    <dbReference type="eggNOG" id="ENOG502RXSB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016574_2_1_1"/>
    <dbReference type="InParanoid" id="G4MKH9"/>
    <dbReference type="OMA" id="KAWYYLR"/>
    <dbReference type="OrthoDB" id="4132249at2759"/>
    <dbReference type="PHI-base" id="PHI:3310"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668:SF20">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="514"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="524"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="540"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="618"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA57568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="753" mass="83431" checksum="90E9FF52AB2BE202" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML15</accession>
    <name>G4ML15_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="3">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08626</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="3"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711055.1">
        <property type="nucleotide sequence ID" value="XM_003711007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML15"/>
    <dbReference type="FunCoup" id="G4ML15">
        <property type="interactions" value="314"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ML15"/>
    <dbReference type="GeneID" id="2679065"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08626"/>
    <dbReference type="eggNOG" id="KOG2529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4ML15"/>
    <dbReference type="OrthoDB" id="9995526at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="7">
        <location>
            <begin position="84"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="243"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="443"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="257"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA58443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="503" mass="55519" checksum="2A55E3AA474878CF" modified="2011-12-14" version="1">MKRSLWKLADMVIPSVTGLDGIFAINKPMGMSSAQVIRDCQAYFQPSRLFAPMLAREAEEARRDAATQGKHNRKWKKRKQDPRVKMGHGGTLDPLATGVLILGVGRATKSLQNFLECTKTYETIVVFGAATDTYDRVGRILAKKSYDEITRDKVEKQLDAFRGKYKQMPPLYSALKMNGKPLYEYAREGKPIPREIETREVEVLGLELLEWYEPGTHNHRWPTEEAGIAEKSLAESVWRVEHEQATGKKLTPEQGAEEDRAFAAHQSFKEQAEERQDKLVFERGQKRKAEESNGRPNKKQQGKQGREQLMSGALGELPPGGPSKGRGSDLVPPAPSADTPPPWDGKGPPACKIRMTVTSGFYVRSFAHELGEKVGSAALMAELVRNRQGDFVLEGDNCLEYDDLVKGEDAWGPKLEKVLHQWSSTHLQGVGPLKSVYAEEPKTTAVNQEGPSGTAADKKPATDEKPAAASVEESQTKESGVKAEETKPTDTKEPEPTAGPSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML52</accession>
    <name>G4ML52_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetratricopeptide repeat protein 36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TTC36 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709400.1">
        <property type="nucleotide sequence ID" value="XM_003709352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML52"/>
    <dbReference type="STRING" id="242507.G4ML52"/>
    <dbReference type="GeneID" id="2684865"/>
    <dbReference type="KEGG" id="mgr:MGG_06692"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06692"/>
    <dbReference type="eggNOG" id="KOG4555">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074601_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML52"/>
    <dbReference type="OMA" id="ILYKAAR"/>
    <dbReference type="OrthoDB" id="539634at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006570">
        <property type="term" value="P:tyrosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038906">
        <property type="entry name" value="TTC36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405">
        <property type="entry name" value="CDNA SEQUENCE BC021608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="29130" checksum="618E30DA84046119" modified="2011-12-14" version="1">MASATLSSRDMNVLEKIKDPEFDPAAVVRLEASLPADPHIKDADVYKKVVERERGIVAQMQQAEDQLEKADAQDAVEATYRKAVLSFDELIQEYPDYASARNNRAQALRRLYGDTMMLPQKEPSPQALVPKIDDTEEHSRVVNKTLADLDRAIELLSPRTPWQALSPAAANTLSLAHTQRAAIYLAASKLVAQGVPQISHGRKESSWRTLEFEAAASRDFAIGGRYGNDIAKGLAVSTNPTAKLCGQMVQEMMKKEYGDEFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML60</accession>
    <name>G4ML60_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709408.1">
        <property type="nucleotide sequence ID" value="XM_003709360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML60"/>
    <dbReference type="GeneID" id="12984469"/>
    <dbReference type="KEGG" id="mgr:MGG_16157"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16157"/>
    <dbReference type="HOGENOM" id="CLU_1922074_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML60"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="132" mass="13779" checksum="7FA5F2FD798BB6B6" modified="2011-12-14" version="1">MSAEGGVGVSGRAGGGGQLGFFEVDAMKTGGKSNSFARIETVEVEVVWRFEGGGIVRPMLPRDNPRLGGCPSPPSGPAIWPDGVQRKTRSRSLRNSKVEGSMAFVVGISASRLGNFASTVKSDRAPGWVGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMA1</accession>
    <name>G4MMA1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_16392</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710394.1">
        <property type="nucleotide sequence ID" value="XM_003710346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMA1"/>
    <dbReference type="SMR" id="G4MMA1"/>
    <dbReference type="FunCoup" id="G4MMA1">
        <property type="interactions" value="301"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MMA1"/>
    <dbReference type="GeneID" id="12986313"/>
    <dbReference type="KEGG" id="mgr:MGG_16392"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16392"/>
    <dbReference type="eggNOG" id="KOG0682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_33_0_1"/>
    <dbReference type="InParanoid" id="G4MMA1"/>
    <dbReference type="OMA" id="FVFYQFA"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000003">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="33"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="459"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA57782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="485" mass="51666" checksum="C2ED0B1046CF8E0A" modified="2011-12-14" version="1">MSSSPVEYNGTLPTGGDSLTEDLNIYYSSGDFAWIMTSSALVLLMIPGVGFFYSGLARRKSALALIWLSLMSIGVASFQWFFWGYSLAFSHTGESGFIGDLANIGLKDVLGQPSVGSSKLPDLLFCLYQGMFAAITPALAIGAAADRGRMLPAMVFVFVWATIVYDPIAYWTWNPNGWSFKLGGLDFAGGTPVHISSGAAALAYSLMLGKRAGYDSNAGMPFRPHNVTHVVLGTVMLYVGWFGFNGGSALAANLRAVMALLVTNISAAVGGLTWCFLDYRLEKKWSTIGFCSGVIAGLVAITPAAGYVPAWSAVIFGVVGGAACNFATKIKFLLGIDEALDIFAEHCVGGIVGNLLTGIFAADYIAHLDGATEIPGGWLNQNYIQLAYQLADCVAGFSYSFVMTCIILFLMNLIPGLSLRVSAAEENMGLDDAQIGEFAYDYVELTRHFEDAAVTTPAVGSSQGSIKEPRTKETQEVSKTETTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMF5</accession>
    <name>G4MMF5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Stress-response A/B barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708753.1">
        <property type="nucleotide sequence ID" value="XM_003708705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMF5"/>
    <dbReference type="SMR" id="G4MMF5"/>
    <dbReference type="GeneID" id="12985662"/>
    <dbReference type="KEGG" id="mgr:MGG_15996"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15996"/>
    <dbReference type="eggNOG" id="ENOG502S73V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080664_2_1_1"/>
    <dbReference type="InParanoid" id="G4MMF5"/>
    <dbReference type="OMA" id="FEWKPTA"/>
    <dbReference type="OrthoDB" id="1601230at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044662">
        <property type="entry name" value="HS1/DABB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178:SF10">
        <property type="entry name" value="STRESS-RESPONSE A_B BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="2">
        <location>
            <begin position="3"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="110" mass="12317" checksum="40D2EFAA78E28C09" modified="2011-12-14" version="1">MTVKHIVLFQFKADARPEAIQEVCSNMVALKDNCLHPASQMPYIKSMSGGKDNSPENLQNGIQYAFVAEFESLEDRDYYVAKDPTHQSFVKNAGQIIEKAIVVDYTIGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP01</accession>
    <name>G4MP01_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphodiesterase</fullName>
            <ecNumber evidence="3">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_05664</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="3">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="3"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710562.1">
        <property type="nucleotide sequence ID" value="XM_003710514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP01"/>
    <dbReference type="SMR" id="G4MP01"/>
    <dbReference type="STRING" id="242507.G4MP01"/>
    <dbReference type="GeneID" id="2676005"/>
    <dbReference type="KEGG" id="mgr:MGG_05664"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05664"/>
    <dbReference type="eggNOG" id="KOG3689">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010668_1_0_1"/>
    <dbReference type="InParanoid" id="G4MP01"/>
    <dbReference type="OMA" id="GFMNMFA"/>
    <dbReference type="OrthoDB" id="546632at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
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                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
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                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
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                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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                <person name="Kim S."/>
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                <person name="Bohnert H."/>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Young S.K."/>
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                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
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                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CENP-H/MCM16 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA58357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003710921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS99"/>
    <dbReference type="SMR" id="G4MS99"/>
    <dbReference type="GeneID" id="2678073"/>
    <dbReference type="KEGG" id="mgr:MGG_04487"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04487"/>
    <dbReference type="eggNOG" id="ENOG502S9QV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078299_0_0_1"/>
    <dbReference type="InParanoid" id="G4MS99"/>
    <dbReference type="OMA" id="WRVMKGV"/>
    <dbReference type="OrthoDB" id="2274804at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043515">
        <property type="term" value="F:kinetochore binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040034">
        <property type="entry name" value="CENP-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008426">
        <property type="entry name" value="CENP-H_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48122">
        <property type="entry name" value="CENTROMERE PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48122:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05837">
        <property type="entry name" value="CENP-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centromere protein H C-terminal" evidence="9">
        <location>
            <begin position="31"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA58357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="236" mass="25742" checksum="C028446A4DB7F8D7" modified="2011-12-14" version="1">MPSIPPTEDAQMRDAPTDDDATQPIISADEERVLKLFDRLQELQLQIALVKARNAYKPTSEPDTPEAVKAAQARLLDARAGYMLRNQVVESVVSATPILHAVHGAKNANLIEQDLKDTLKARDAASIAVANQTTALHETLDKLTSVEADSLALSRKNVELAAEMLDLVQEHEARRKGVTADEDPDTAAEIRRLEGQVQASRRRWRIMKGTAGAVVVGSGVDWVGDPVLRDVVLDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSD4</accession>
    <name>G4MSD4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713553.1">
        <property type="nucleotide sequence ID" value="XM_003713505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSD4"/>
    <dbReference type="SMR" id="G4MSD4"/>
    <dbReference type="GeneID" id="2678155"/>
    <dbReference type="KEGG" id="mgr:MGG_04457"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04457"/>
    <dbReference type="eggNOG" id="ENOG502ST5U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133420_1_0_1"/>
    <dbReference type="InParanoid" id="G4MSD4"/>
    <dbReference type="OMA" id="QHIQDLG"/>
    <dbReference type="OrthoDB" id="5415072at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="127" mass="13161" checksum="4F6414C9649225B4" modified="2011-12-14" version="1">MGNCFGKPDSSSGDNNAGGARPSNNNQTPSASASGQKKKPHTTGKGRTLGEAASSGSSAVPPTAAADAARQAALDRHSENNKKTGGKIGSSLQAQKKMTDRQVLSQAAEESRRQRELDDQARALRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSK8</accession>
    <name>G4MSK8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase 2-nitropropane dioxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_01473</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714431.1">
        <property type="nucleotide sequence ID" value="XM_003714383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSK8"/>
    <dbReference type="SMR" id="G4MSK8"/>
    <dbReference type="GeneID" id="2679667"/>
    <dbReference type="KEGG" id="mgr:MGG_01473"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01473"/>
    <dbReference type="eggNOG" id="ENOG502QTWN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038732_2_3_1"/>
    <dbReference type="InParanoid" id="G4MSK8"/>
    <dbReference type="OMA" id="RAKPKAW"/>
    <dbReference type="OrthoDB" id="10265891at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA54624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="387" mass="41028" checksum="7BA9CC8314387CDC" modified="2011-12-14" version="1">MASPQKIRTPITDLFKIQHPVMLAGMNVAAGPKLAAAVTNAGGLGVIGGVGYTPEMLKDQIAELKHHLTDKNAPFGVDLLLPQVGGNARKTNYDYTKGKLDELVDIIIAEGAKLFVSAVGVPPKHVVDRLHKHGILYMNMIGHPKHVAKCLSLGVDIICAQGGEGGGHTGNIPTTILIPSVVKACQGHKSPLTGGPVQVVAAGGIFNGQTVAAALMLGASAVWVGTRFILTHEAGAPESHKEAVRTAGYDDTIKTVIFTGRPLRVKKNPYILNWENDRQDEIKELTAKGILPYESDLDKIMGGEEGPNFDIASGEAKGKDDKKPNVETEEDVDIDDLMDQFRPFLMGKCAAVVNELKSAKEVVDELVNDGAACLGQGGQMVKASAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MST1</accession>
    <name>G4MST1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Inosine-uridine preferring nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_04540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713592.1">
        <property type="nucleotide sequence ID" value="XM_003713544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MST1"/>
    <dbReference type="SMR" id="G4MST1"/>
    <dbReference type="STRING" id="242507.G4MST1"/>
    <dbReference type="GeneID" id="2678210"/>
    <dbReference type="KEGG" id="mgr:MGG_04540"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04540"/>
    <dbReference type="eggNOG" id="KOG2938">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036838_9_0_1"/>
    <dbReference type="InParanoid" id="G4MST1"/>
    <dbReference type="OMA" id="RNVVSMF"/>
    <dbReference type="OrthoDB" id="5783963at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF56">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="7"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA53785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="433" mass="47290" checksum="780060198867D7A6" modified="2011-12-14" version="1">MAPKHRIIIDTDPGVDDVLAILLALSASPEDLEVAMISVTYGNVPLQGCLRNAVALFHVLEKERAWRKSVGKETGFESLSVFKPIVAIGAKHPLEEEELAADHFHGADGLHGVHDAHPDLTPAETWRTLFEDAPGGAPSDIPSFSTYFTPSKTLAHKEILRILKESPDQTVTILTIGPMTNLALAAAEDPETLLRAREVCVMGGAINVPGNITPVAEFNTFADAVATARVFALTAREPASTMPPCTSPSLKPYPEGLSRQLKLSLFPLDITTDHLLNKGFFTERIAPLVASGSPLARWLEHVLSRTFDKIDSILGDGSEPGLSLHDPLTVWYMMTRDNPAWKASAGEDIRVETAGQWTRGMHILDRRVRSKPGVKQEAGQAEKTEVVDGVQLDEVPGDTMGWLSRRRGNSVNRIVGSPGFNIFAEYLMKQLFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSV5</accession>
    <name>G4MSV5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Trafficking protein particle complex II-specific subunit 65 IgD3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713616.1">
        <property type="nucleotide sequence ID" value="XM_003713568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSV5"/>
    <dbReference type="STRING" id="242507.G4MSV5"/>
    <dbReference type="GeneID" id="2677987"/>
    <dbReference type="KEGG" id="mgr:MGG_04601"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04601"/>
    <dbReference type="eggNOG" id="ENOG502SGQ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015118_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSV5"/>
    <dbReference type="OMA" id="IFSWTVY"/>
    <dbReference type="OrthoDB" id="5345392at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055420">
        <property type="entry name" value="IgD3_Trs65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024662">
        <property type="entry name" value="Trs65"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28159">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX II-SPECIFIC SUBUNIT 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28159:SF1">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX II-SPECIFIC SUBUNIT 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12735">
        <property type="entry name" value="IgD3_Trs65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex II-specific subunit 65 IgD3" evidence="2">
        <location>
            <begin position="455"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="540"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="655" mass="71291" checksum="A38564310FFC3298" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSV7</accession>
    <name>G4MSV7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713618.1">
        <property type="nucleotide sequence ID" value="XM_003713570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSV7"/>
    <dbReference type="GeneID" id="2677989"/>
    <dbReference type="KEGG" id="mgr:MGG_04603"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04603"/>
    <dbReference type="eggNOG" id="ENOG502RMQW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_894498_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSV7"/>
    <dbReference type="OMA" id="RYAGGNI"/>
    <dbReference type="OrthoDB" id="5245529at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466101" evidence="2">
        <location>
            <begin position="21"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="311" mass="29599" checksum="B5CADAF096944880" modified="2011-12-14" version="1">MKNFGSISLLLLAATSYVAARPAVEISDLRMHVRSSEAAAPVVADAAAAAPAAEEKKKEGAAAAPAAEEKKKEGAAAAPAPVAAAPVAGANATAPAAGQGKDAKGKDAKGKDAKGKEAKAKDGKKAKAGAGAANATAPADKKRKKANAKKADLKKGAAKAGAGAANATAPAGKEGKKAKKAGGANLAAGNGTAVDAGKGKKDKDAKGKDAKGKDAKGKDAKGKDAEGKDAKKSLDSLLAQLGGGAAGAGKANAGEGAGATGGLQSLLTQLQGLTGGAGQGGGVGNLLAQLGGGAAKKTAKRSPVTLVQDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSW8</accession>
    <name>G4MSW8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase S59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_04617</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin GLFG family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713629.1">
        <property type="nucleotide sequence ID" value="XM_003713581.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MSW8"/>
    <dbReference type="FunCoup" id="G4MSW8">
        <property type="interactions" value="728"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSW8"/>
    <dbReference type="MEROPS" id="S59.A07"/>
    <dbReference type="GeneID" id="2677933"/>
    <dbReference type="KEGG" id="mgr:MGG_04617"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04617"/>
    <dbReference type="eggNOG" id="KOG0845">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002330_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSW8"/>
    <dbReference type="OMA" id="PMGKGLN"/>
    <dbReference type="OrthoDB" id="3797628at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034398">
        <property type="term" value="P:telomere tethering at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1610.10:FF:000003">
        <property type="entry name" value="Nucleoporin SONB, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1610.10">
        <property type="entry name" value="Peptidase S59, nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037665">
        <property type="entry name" value="Nucleoporin_S59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007230">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036903">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021967">
        <property type="entry name" value="Nup98_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198">
        <property type="entry name" value="NUCLEOPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04096">
        <property type="entry name" value="Nucleoporin2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12110">
        <property type="entry name" value="Nup96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82215">
        <property type="entry name" value="C-terminal autoproteolytic domain of nucleoporin nup98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51434">
        <property type="entry name" value="NUP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase S59" evidence="12">
        <location>
            <begin position="899"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="422"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="552"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="814"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="881"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1040"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1107"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="887"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1040"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1051"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1067"/>
            <end position="1077"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA53822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1906" mass="200109" checksum="92D459C0DB62AADC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTA6</accession>
    <name>G4MTA6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tafazzin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_04664</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a cardiolipin + a 1-acyl-sn-glycero-3-phosphocholine</text>
            <dbReference type="Rhea" id="RHEA:33731"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64743"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:33732"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:33733"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the taffazin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713659.1">
        <property type="nucleotide sequence ID" value="XM_003713611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTA6"/>
    <dbReference type="SMR" id="G4MTA6"/>
    <dbReference type="FunCoup" id="G4MTA6">
        <property type="interactions" value="102"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTA6"/>
    <dbReference type="GeneID" id="2678141"/>
    <dbReference type="KEGG" id="mgr:MGG_04664"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04664"/>
    <dbReference type="eggNOG" id="KOG2847">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046747_1_0_1"/>
    <dbReference type="InParanoid" id="G4MTA6"/>
    <dbReference type="OMA" id="IMRYFKW"/>
    <dbReference type="OrthoDB" id="193467at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047184">
        <property type="term" value="F:1-acylglycerophosphocholine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035965">
        <property type="term" value="P:cardiolipin acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000872">
        <property type="entry name" value="Tafazzin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497:SF0">
        <property type="entry name" value="TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497">
        <property type="entry name" value="TAZ PROTEIN TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00979">
        <property type="entry name" value="TAFAZZIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="14">
        <location>
            <begin position="66"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="155"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA53852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="381" mass="42794" checksum="B5F357FBF9A2DC10" modified="2011-12-14" version="1">MGVTANGPPQQPSLTWRNTSSILIGLSVAVSKGFLYGLNKVETIGLERFVELIEQRRDVKKRTKGLITVSNHISIIDDPLIWGVLPLKYSFNQSNLRWSLAAHDICFQNPVLTTFFNLGKTLPTYRFRHSPHGGLFQPTMSDAIRILSSEQHGLKYLTPPPSPSSSTPGPLLQYPPTPSDPAPPAPSYQPWDRHGWVHIFPEACVHQHPERALRYFKWGVARLVLESGPEPPDVVPMFIDGTDRVMHEDRGFPRFLPRVGRRVRVVFGEPLDFDLAFGDLKRKWDALVASAADAAASRAASSRWRVAFPAETVDLEHGEEARAIRVEVTRRIRDEVLKLRHGLGYPDQDPEMGLAETWAREPGVGYTYKSRVDGSKVNEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTU3</accession>
    <name>G4MTU3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Periodic tryptophan protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_04802</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713739.1">
        <property type="nucleotide sequence ID" value="XM_003713691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTU3"/>
    <dbReference type="SMR" id="G4MTU3"/>
    <dbReference type="FunCoup" id="G4MTU3">
        <property type="interactions" value="1400"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTU3"/>
    <dbReference type="GeneID" id="2677755"/>
    <dbReference type="KEGG" id="mgr:MGG_04802"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04802"/>
    <dbReference type="eggNOG" id="KOG0270">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023867_0_1_1"/>
    <dbReference type="InParanoid" id="G4MTU3"/>
    <dbReference type="OMA" id="CFVPRGV"/>
    <dbReference type="OrthoDB" id="270624at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000457">
        <property type="entry name" value="rRNA processing protein Pwp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001345">
        <property type="entry name" value="WD40 repeat-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044285">
        <property type="entry name" value="PWP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="271"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="407"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="44"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="513"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="521"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="551" mass="60900" checksum="5656C621C3502EB3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU67</accession>
    <name>G4MU67_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Aminomethyltransferase</fullName>
            <ecNumber evidence="4 12">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 12">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_04826</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)-5,6,7,8-tetrahydrofolate = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="4 12"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713755.1">
        <property type="nucleotide sequence ID" value="XM_003713707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU67"/>
    <dbReference type="SMR" id="G4MU67"/>
    <dbReference type="FunCoup" id="G4MU67">
        <property type="interactions" value="1205"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MU67"/>
    <dbReference type="GeneID" id="2678053"/>
    <dbReference type="KEGG" id="mgr:MGG_04826"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04826"/>
    <dbReference type="eggNOG" id="KOG2770">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_10_0_1"/>
    <dbReference type="InParanoid" id="G4MU67"/>
    <dbReference type="OMA" id="MPVQYPA"/>
    <dbReference type="OrthoDB" id="10263536at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.110:FF:000002">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1400:FF:000001">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1250.10:FF:000002">
        <property type="entry name" value="Aminomethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1250.10">
        <property type="entry name" value="Aminomethyltransferase fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001567">
        <property type="entry name" value="PRK00389.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF2">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006487">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="GCVT N-terminal" evidence="13">
        <location>
            <begin position="79"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="14">
        <location>
            <begin position="378"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006487-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA53948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="464" mass="49861" checksum="18B2CD55C88D6505" modified="2011-12-14" version="1">MRGLTPLRTLARPARLCLRQPQRNLSRVSVTAKSQGRYSEVVKRPVLAATTNELRAIQTEAQRRHASGSSGEVLHKTALYDLHVAHGGKMVPFAGYHMPVQYSSLSVSASHVFTREKASLFDVGHMVQRRFSGPGAAAFLERVTPSGVAALKPHHGSLTTLLHRGTGGIVDDTIVTRLDDELFYVVTNAGCRDKDNKYFADELAAWDGATVKHEVMDGWGLVALQGPLAKDILAEALAEPAEVDLPNLHFGMSRYGRIKLLGMEVSAPLLISRGGYTGEDGFEISIPEDETVAVTQALLTTGRPERLQLAGLGARDSLRLEAGMCLYGHDLDDTTTPVEAGLSWVIPKARRETAGFHGAEVILPQLVAKSKGGKGVERRRVGLVVEGAPAREGADIVSSDGATKLGKITSGCPSPTLGKNIAMGYIQDGQHKAGTEVAVLVRGKPRKAVVTKMPFIQTKYWKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU97</accession>
    <name>G4MU97_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">6-phosphogluconolactonase</fullName>
            <shortName evidence="6">6PGL</shortName>
            <ecNumber evidence="4 6">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_10148</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="4 6"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713785.1">
        <property type="nucleotide sequence ID" value="XM_003713737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU97"/>
    <dbReference type="SMR" id="G4MU97"/>
    <dbReference type="FunCoup" id="G4MU97">
        <property type="interactions" value="266"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MU97"/>
    <dbReference type="GeneID" id="2681759"/>
    <dbReference type="KEGG" id="mgr:MGG_10148"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10148"/>
    <dbReference type="eggNOG" id="KOG3147">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053947_0_1_1"/>
    <dbReference type="InParanoid" id="G4MU97"/>
    <dbReference type="OMA" id="IAMSQST"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000005">
        <property type="entry name" value="6-phosphogluconolactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="6PGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054:SF0">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA53978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="259" mass="28201" checksum="B767C8BEF6960C1E" modified="2011-12-14" version="1">MGKQANLFAFAGVDALAPALRSYVIQCQDAGITRHDVFKVAVSGGSLPKTLAQALLAAPGPGEPAVRWDKWEIFFADERAVPLDHEDSNYGLLKKELLDKIEGPQPTVHAIDTEVLGDTQELADRYEQTLVRSFASRDSVKLPIFDLLLLGCGPDGHTCSLFPGHELLRETSAWVAPIEDSPKPPPRRITLTLPVVTHSVRVAFVATGGGKKEIMKEIFDQESGLPCALVNQGTGDRCSWFVDNPAVEGVSFPRRSFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUM3</accession>
    <name>G4MUM3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_10164</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ING family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713803.1">
        <property type="nucleotide sequence ID" value="XM_003713755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUM3"/>
    <dbReference type="SMR" id="G4MUM3"/>
    <dbReference type="STRING" id="242507.G4MUM3"/>
    <dbReference type="GeneID" id="2681791"/>
    <dbReference type="KEGG" id="mgr:MGG_10164"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10164"/>
    <dbReference type="eggNOG" id="KOG1973">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009357_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUM3"/>
    <dbReference type="OMA" id="EVMIHRE"/>
    <dbReference type="OrthoDB" id="5411773at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15505">
        <property type="entry name" value="PHD_ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333:SF94">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11940)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="755"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="173"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="427"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="494"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="528"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
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            <position position="758"/>
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            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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            <position position="760"/>
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            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
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            <position position="771"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
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        </ligand>
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        <location>
            <position position="776"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
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            <position position="782"/>
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            <position position="800"/>
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            <position position="803"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
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        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00010210"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA53996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="822" mass="89070" checksum="0A3DC691531DFCEA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUQ0</accession>
    <name>G4MUQ0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Leucine Rich Repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_10199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003713782.1"/>
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    <dbReference type="STRING" id="242507.G4MUQ0"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_10199"/>
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    <dbReference type="HOGENOM" id="CLU_009538_0_0_1"/>
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    <dbReference type="OMA" id="RQDFGNT"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="Leucine Rich Repeat domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
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    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LRR"/>
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    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="688"/>
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        <location>
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        </location>
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        <location>
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        <location>
            <begin position="413"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA54023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="866" mass="95121" checksum="3547BC82412F9162" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUQ3</accession>
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        <recommendedName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase</fullName>
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    </protein>
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        <name evidence="12" type="ORF">MGG_10202</name>
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    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713833.1">
        <property type="nucleotide sequence ID" value="XM_003713785.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MUQ3"/>
    <dbReference type="SMR" id="G4MUQ3"/>
    <dbReference type="FunCoup" id="G4MUQ3">
        <property type="interactions" value="444"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUQ3"/>
    <dbReference type="GeneID" id="2681774"/>
    <dbReference type="KEGG" id="mgr:MGG_10202"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10202"/>
    <dbReference type="eggNOG" id="KOG1394">
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    <dbReference type="HOGENOM" id="CLU_000022_69_2_1"/>
    <dbReference type="InParanoid" id="G4MUQ3"/>
    <dbReference type="OMA" id="QIGHCLG"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000009">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005589">
        <property type="entry name" value="PRK07314.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF336">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="11">
        <location>
            <begin position="3"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="active site" description="For beta-ketoacyl synthase activity" evidence="9">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA54026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="459" mass="47889" checksum="472E76EBAC04909F" modified="2011-12-14" version="1">MSLRRVVVTGIGAVTPLGVGAQRSWQRLIAGASGITSVTHLEPLDRWQELPSTVAGLVPTSAAADANANAAKSHGGAGDVDGGKASGLWRPSDWLDATDQRRMSRFAQYALASADMALEDARWMPETPHDLEATGVCLGSGIGNLEEIYNTALAHHKHGYKKVSPLFAPKILINLAAGHIAMHHGFRGPNHAATTACTTGAHSIGDAARFIAFGDADVMVAGGSESCIHPLTFAGFARSRSLSTAFNDNPTASCRPFDESRDGFVVAEGAAVVVLEELEHALRRGARILAELRGYGCSGDAHHMTAPREDGSGALAAMKKALKHAGVRPAEVDYINAHATGTRSGDAAEALAIRSLMLGEEGLEREDQVTVSSTKGSTGHLLGAAGAVEAVFTALAVAENRVPPTKNLFNPGVGPNFNFVANQTQERTVNVAVSNSFGFGGTNASLVFSKLERGMQGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUX8</accession>
    <name>G4MUX8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_07291</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715519.1">
        <property type="nucleotide sequence ID" value="XM_003715471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUX8"/>
    <dbReference type="SMR" id="G4MUX8"/>
    <dbReference type="STRING" id="242507.G4MUX8"/>
    <dbReference type="GeneID" id="2683187"/>
    <dbReference type="KEGG" id="mgr:MGG_07291"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07291"/>
    <dbReference type="eggNOG" id="KOG0600">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_17_4_1"/>
    <dbReference type="InParanoid" id="G4MUX8"/>
    <dbReference type="OMA" id="NRIITLW"/>
    <dbReference type="OrthoDB" id="204883at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008024">
        <property type="term" value="C:cyclin/CDK positive transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07840">
        <property type="entry name" value="STKc_CDK9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000440">
        <property type="entry name" value="Serine/threonine-protein kinase bur1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000270">
        <property type="entry name" value="Serine/threonine-protein kinase bur1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF546">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="817"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1129"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="152"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="282"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="377"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="499"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="596"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="621"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="637"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="658"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="728"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="762"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1129"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1167"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="846"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA55712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1198" mass="133253" checksum="D688291DC635FDC0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV87</accession>
    <name>G4MV87_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable electron transfer flavoprotein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_01719</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9 10">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714716.1">
        <property type="nucleotide sequence ID" value="XM_003714668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV87"/>
    <dbReference type="SMR" id="G4MV87"/>
    <dbReference type="FunCoup" id="G4MV87">
        <property type="interactions" value="508"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MV87"/>
    <dbReference type="GeneID" id="2679775"/>
    <dbReference type="KEGG" id="mgr:MGG_01719"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01719"/>
    <dbReference type="eggNOG" id="KOG3954">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034178_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV87"/>
    <dbReference type="OMA" id="WRPYAEQ"/>
    <dbReference type="OrthoDB" id="1715808at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000041">
        <property type="entry name" value="Electron transfer flavoprotein alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000001">
        <property type="entry name" value="Electron transfer flavoprotein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 9 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="11">
        <location>
            <begin position="35"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="262"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="276"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="293"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000089-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA54909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="347" mass="35622" checksum="190C1545E471EE54" modified="2011-12-14" version="1">MLSAARRAVLGQASTRPASAVFAMSPSAFRRLLSSLAVLEQRDGKLNAGSLSAVTAAQKLGGSVHAIVAGSSVKGVAEAAAKVGGVEKVLVVENSAYEKGLPENYAPLLVENIKKGGYTHVIAGHTAFGKKLMPRVAALLDSQQISDITAVESEDTFVRPIYAGNAIATVQSSDPIKIITIRGTAFQAAPAEGGSAAIEDGADPKAECESEWVSEDLAKSDRPDLATAGRVVSGGRGLKSKDEFDKVMLPLADALGAAVGASRAAVDSGYADNSLQVGQTGKVVAPQLYMAVGISGAIQHLAGMKDSKVIAAINKDADAPIFQVADVGLVGDLFEKVPELTEKLGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVU6</accession>
    <name>G4MVU6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_10804</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715621.1">
        <property type="nucleotide sequence ID" value="XM_003715573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVU6"/>
    <dbReference type="SMR" id="G4MVU6"/>
    <dbReference type="GeneID" id="2676335"/>
    <dbReference type="KEGG" id="mgr:MGG_10804"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10804"/>
    <dbReference type="HOGENOM" id="CLU_1603061_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVU6"/>
    <dbReference type="OMA" id="VHCETPP"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="166" mass="17961" checksum="ADD0550167CFAB50" modified="2011-12-14" version="1">MFHIRFSSLAPCSVLCPLLAISQKAVFTSTSPRKKADAGYLRFQPSIDFAADGCYNRPAVDKNGSVSAGLPFAAMGLPRRGGPRQQQRRRMATATSSRSLAFAWMVHCETPPRGLGSMVLWFNGSSRPTLAAVTWLSRVGTLPRTSSAVRHYGNEGDGARSEEGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW38</accession>
    <name>G4MW38_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713998.1">
        <property type="nucleotide sequence ID" value="XM_003713950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW38"/>
    <dbReference type="GeneID" id="2679945"/>
    <dbReference type="KEGG" id="mgr:MGG_11292"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11292"/>
    <dbReference type="HOGENOM" id="CLU_1713630_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW38"/>
    <dbReference type="OrthoDB" id="10575511at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465690" evidence="2">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="153" mass="15894" checksum="884F82A6E078B70C" modified="2011-12-14" version="1">MVAKGLLLALLPLVPLTAAAPTCGPNTLERRAGRGIMGIGDIRQDECGPGRSCRRPSAGPAPGRYQSGPCERIGAYLDSVGGLVPPSPSVSGQGRRLDETVVYDDQGNPRWANHNKPDPRGAAAQAAMARAKPQKASGAGSSKSKKKSFFGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWI8</accession>
    <name>G4MWI8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714043.1">
        <property type="nucleotide sequence ID" value="XM_003713995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWI8"/>
    <dbReference type="SMR" id="G4MWI8"/>
    <dbReference type="STRING" id="242507.G4MWI8"/>
    <dbReference type="GeneID" id="2676238"/>
    <dbReference type="KEGG" id="mgr:MGG_14499"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14499"/>
    <dbReference type="eggNOG" id="KOG0594">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017513_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWI8"/>
    <dbReference type="OMA" id="HMENTEL"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359:SF37">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24359">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SBK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="263"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="683" mass="77309" checksum="10AC0687998D7797" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX35</accession>
    <name>G4MX35_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07987</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714940.1">
        <property type="nucleotide sequence ID" value="XM_003714892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX35"/>
    <dbReference type="GeneID" id="2678246"/>
    <dbReference type="KEGG" id="mgr:MGG_07987"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07987"/>
    <dbReference type="eggNOG" id="ENOG502SHVM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_7_1"/>
    <dbReference type="InParanoid" id="G4MX35"/>
    <dbReference type="OMA" id="MAIVKCT"/>
    <dbReference type="OrthoDB" id="5429740at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="36"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="283"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="302"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="393" mass="42578" checksum="161ECC18D3FE656F" modified="2011-12-14" version="1">MPAVGSPEWLAEDKGAEILISCWVSTLISSAFVLSRVYVNGFMRQKLRSDDWFIITGQFCGYLAVGFSTVAVIRGNGRHMAALSLEQQSGVRLWTTVGFVPGLLSFGLPKLAVASLLTRLLNPRRFHRWFLWWLAVWCLLSVSTTGILSLVHCTPASSMWDVSVEGSCTDVRNLIYFGLYAGAFSAFVDVYLAVYPAVVLFGLQMSLKKKVVLSSALGIGSISSAVAIYKTTRLPSIGSEDFSYDTSDLVIWTVVEGSAIIIAASIPVLQPLLEVIKKRNPFTSHERSKRDSPSFGSGWRGYRFEPSERVGGKQKQRDGRGFAVAADASGFEELLSPLDKTLTSYVAEASPAPPASSTSGHDAEKGFAGGVPAGVANGRIMRTDVVDVSYHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX64</accession>
    <name>G4MX64_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_08017</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714969.1">
        <property type="nucleotide sequence ID" value="XM_003714921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX64"/>
    <dbReference type="GeneID" id="2678283"/>
    <dbReference type="KEGG" id="mgr:MGG_08017"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08017"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024939_0_0_1"/>
    <dbReference type="InParanoid" id="G4MX64"/>
    <dbReference type="OMA" id="VFQGLGW"/>
    <dbReference type="OrthoDB" id="5215911at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF68">
        <property type="entry name" value="MULTIDRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="510"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="572"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="625"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="652"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="194"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="704" mass="74981" checksum="6D25494A461CDCE2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXB6</accession>
    <name>G4MXB6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715821.1">
        <property type="nucleotide sequence ID" value="XM_003715773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXB6"/>
    <dbReference type="GeneID" id="12986780"/>
    <dbReference type="KEGG" id="mgr:MGG_15960"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15960"/>
    <dbReference type="HOGENOM" id="CLU_2812894_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXB6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465743" evidence="2">
        <location>
            <begin position="23"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="67" mass="7130" checksum="8D7862CBA34ADEEC" modified="2011-12-14" version="1">MQLATVFAAAATLAVLPTGVLAGPRYIPHPECEVTIMKPGTPSPRSPYTLPEEYDRGYGPGDSKTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXM3</accession>
    <name>G4MXM3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714161.1">
        <property type="nucleotide sequence ID" value="XM_003714113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXM3"/>
    <dbReference type="GeneID" id="2679484"/>
    <dbReference type="KEGG" id="mgr:MGG_01252"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01252"/>
    <dbReference type="eggNOG" id="ENOG502RMK0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2399813_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXM3"/>
    <dbReference type="OrthoDB" id="5121433at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="107" mass="11638" checksum="3A9266EE7D17339B" modified="2011-12-14" version="1">MNINDLNNSGPSSADQTASMSAAAAYAAAQGDAAAARQIASGQWSTKRMQEEFDHAKAGLVHKDFKPTDYPDPLRPRHGFKNPYAGKYPQDAEKQLKEFLNRADAKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2025-02-05" modified="2025-04-09" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYD3</accession>
    <name>BIP1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor BIP1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">bZIP TF involved in pathogenesis-1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BIP1</name>
        <name type="ORF">MGG_08118</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2024" name="PLoS Pathog." volume="20" first="e1011945" last="e1011945">
            <title>The bZIP transcription factor BIP1 of the rice blast fungus is essential for infection and regulates a specific set of appressorium genes.</title>
            <authorList>
                <person name="Lambou K."/>
                <person name="Tag A."/>
                <person name="Lassagne A."/>
                <person name="Collemare J."/>
                <person name="Clergeot P.H."/>
                <person name="Barbisan C."/>
                <person name="Perret P."/>
                <person name="Tharreau D."/>
                <person name="Millazo J."/>
                <person name="Chartier E."/>
                <person name="De Vries R.P."/>
                <person name="Hirsch J."/>
                <person name="Morel J.B."/>
                <person name="Beffa R."/>
                <person name="Kroj T."/>
                <person name="Thomas T."/>
                <person name="Lebrun M.H."/>
            </authorList>
            <dbReference type="PubMed" id="38252628"/>
            <dbReference type="DOI" id="10.1371/journal.ppat.1011945"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <scope>TISSUE SPECIFICITY</scope>
        <scope>SUBCELLULAR LOCATION</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Transcription factor that is required for infection of plants hosts (PubMed:38252628). Is not implicated in the development of appressoria or the subsequent penetration of host leaves, but is necessary for the initial establishment of the fungus within plant cells by orchestrating the expression of a unique set of early invasion-related genes within appressoria, encoding secreted effectors, enzymes, secondary metabolism-related enzymes, and signaling membrane receptors (PubMed:38252628). Controls the expression of targeted genes by interacting directly with a 5'-TGACTC-3' motif present in their promoters (PubMed:38252628).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="tissue specificity">
        <text evidence="3">Expressed in appressoria.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="3">Impairs pathogenicity on barley and rice plants, as well as on detached barley leaves (PubMed:38252628). Does not affect the differentiation, turgor build-up and maturation of appressoria but impairs the formation of invasive infection hyphae and completely abolishes the ability to penetrate into barley and rice epidermal cells (PubMed:38252628). Has no effect on conidiation, mycelial growth nor resistance to cell wall and oxidative stress (PubMed:38252628).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the bZIP family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715075.1">
        <property type="nucleotide sequence ID" value="XM_003715027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYD3"/>
    <dbReference type="SMR" id="G4MYD3"/>
    <dbReference type="STRING" id="242507.G4MYD3"/>
    <dbReference type="EnsemblFungi" id="MGG_08118T0">
        <property type="protein sequence ID" value="MGG_08118T0"/>
        <property type="gene ID" value="MGG_08118"/>
    </dbReference>
    <dbReference type="GeneID" id="2678400"/>
    <dbReference type="KEGG" id="mgr:MGG_08118"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08118"/>
    <dbReference type="eggNOG" id="ENOG502SU86">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079681_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYD3"/>
    <dbReference type="OMA" id="AQQSYGH"/>
    <dbReference type="OrthoDB" id="3535998at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37012:SF2">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <feature type="chain" id="PRO_0000461565" description="Transcription factor BIP1">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="bZIP" evidence="1">
        <location>
            <begin position="54"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Basic motif" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Leucine-zipper" evidence="1">
        <location>
            <begin position="82"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="38252628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="4">
        <source>
            <dbReference type="PubMed" id="38252628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="266" mass="29542" checksum="1977DC1DE1781E09" modified="2011-12-14" version="1">MAMYMPSTASSTTHIRSPSGTPIDSPHEMTRSPSAEPSKPAKRKGTRSVSTLTPSQLARKRANDREAQRAIRARTKEHIERLEREVEELKSKQNRDETLQELIRKNKYLEKEIARLRETYGIPTPPTSHPYAPSIYDDSAVSSRTSSSFGQHSPDYHQVGEYGASYMTTPEPSEPWTSVLPCSNVSSPASSGSAEEYGYIPTSVPAGIEGLPPTSRVGACMKYEDMDNENGYPRSNGVPMPPTYMHQQQWPVPYSATVYYPQSPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYM7</accession>
    <name>G4MYM7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_01333</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 13">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714259.1">
        <property type="nucleotide sequence ID" value="XM_003714211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYM7"/>
    <dbReference type="SMR" id="G4MYM7"/>
    <dbReference type="STRING" id="242507.G4MYM7"/>
    <dbReference type="GeneID" id="2679373"/>
    <dbReference type="KEGG" id="mgr:MGG_01333"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01333"/>
    <dbReference type="eggNOG" id="KOG1713">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042628_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYM7"/>
    <dbReference type="OMA" id="PCRKNRF"/>
    <dbReference type="OrthoDB" id="37721at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.80:FF:000002">
        <property type="entry name" value="NADH dehydrogenase iron-sulfur protein 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="entry name" value="NADH:ubiquinone oxidoreductase, 30kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01961">
        <property type="entry name" value="NuoC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004733">
        <property type="entry name" value="PRK06074.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="Nqo5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase 30kDa subunit" evidence="10">
        <location>
            <begin position="108"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="257"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA54452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="291" mass="33141" checksum="8209511D3F80C322" modified="2011-12-14" version="1">MATNVCRSRALASALRPVKPATVRPRTEAAVRLFSVSAARDVVVPKDAPNVRQAPRAPIGKIEVPIVNPADKYASKAENLHRYGQWLMSCLPKYVQQFSLWKDELTIYICPSGVIPVFNFLKYNTSAEFTTVSDITAVDFPTRDQRFEIVYNLLSVRHNARIRVKTYADEASPVPSICSIYDGANWYEREVYDMFGVFFVGHPDLRRIMTDYGFEGHPLRKDFPLTGYTEVRYDEEKKRIVTEPLELTQAFRNFEGGSSAWEQVGPGNDRTPESFKLPTPKPEEPKEEPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZD4</accession>
    <name>G4MZD4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713496.1">
        <property type="nucleotide sequence ID" value="XM_003713448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZD4"/>
    <dbReference type="SMR" id="G4MZD4"/>
    <dbReference type="GeneID" id="2678178"/>
    <dbReference type="KEGG" id="mgr:MGG_04382"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04382"/>
    <dbReference type="eggNOG" id="ENOG502SUMI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_139324_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZD4"/>
    <dbReference type="OMA" id="YHARRTG"/>
    <dbReference type="OrthoDB" id="3529721at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="17581" checksum="37020D84DC382813" modified="2011-12-14" version="1">MSSSLTSPGLTQALYAGNALWFTSAFIHFGFRQKFMMRKISRRKGSAEASIRLTAEGDAWHHDIMAYLGAMNSSLALLAILRIYALARPSRALGGKDGDVAQDVTALIVLGLANFSQAFLNFTLSRRSDRWIMGKGLDRITVLDAVFTVLDWAAAIGRLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZG0</accession>
    <name>G4MZG0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc finger transcription factor ace1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_04428</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713522.1">
        <property type="nucleotide sequence ID" value="XM_003713474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZG0"/>
    <dbReference type="STRING" id="242507.G4MZG0"/>
    <dbReference type="GeneID" id="2678215"/>
    <dbReference type="KEGG" id="mgr:MGG_04428"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04428"/>
    <dbReference type="eggNOG" id="ENOG502S2AR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008243_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZG0"/>
    <dbReference type="OMA" id="PMDINQK"/>
    <dbReference type="OrthoDB" id="9368434at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="123"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="493"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="566"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="500"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="577"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA53715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="737" mass="81321" checksum="B08E6C5B25B24416" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZK6</accession>
    <name>G4MZK6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Gamma interferon inducible lysosomal thiol reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01423</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GILT family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714371.1">
        <property type="nucleotide sequence ID" value="XM_003714323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZK6"/>
    <dbReference type="SMR" id="G4MZK6"/>
    <dbReference type="GeneID" id="2679629"/>
    <dbReference type="KEGG" id="mgr:MGG_01423"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01423"/>
    <dbReference type="eggNOG" id="ENOG502S45F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072148_2_0_1"/>
    <dbReference type="InParanoid" id="G4MZK6"/>
    <dbReference type="OMA" id="GPTECIG"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004911">
        <property type="entry name" value="Interferon-induced_GILT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234">
        <property type="entry name" value="GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234:SF8">
        <property type="entry name" value="GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03227">
        <property type="entry name" value="GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="28574" checksum="A67B74330F5D1EB0" modified="2011-12-14" version="1">MDDIKRYPTPRALPLASSRRSRTFVALAAMGIVSFFFFVHIRPLAALHTTPSVATPWQTHPRPQPGAAVGKQQAPLVPLEAHIMSKCPDARDCLRDMVLPVMERVHDKVNFTLSFIGTPDADSGVACKHGPAECMGNIIELCAADLYPDPKTYLGFTMCISMKFPEIPKRELIETCALEHAVDFKALNDCAAKDDGAYGVDMLRHSVQRTAKAGVKMSCTVRLDQEIYCIRDGGEWVDCPKGPGVQELVAAIEQKYSVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZP2</accession>
    <name>G4MZP2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_07031</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715213.1">
        <property type="nucleotide sequence ID" value="XM_003715165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZP2"/>
    <dbReference type="SMR" id="G4MZP2"/>
    <dbReference type="FunCoup" id="G4MZP2">
        <property type="interactions" value="1050"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZP2"/>
    <dbReference type="MEROPS" id="T01.984"/>
    <dbReference type="GeneID" id="2683045"/>
    <dbReference type="KEGG" id="mgr:MGG_07031"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07031"/>
    <dbReference type="eggNOG" id="KOG0177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_12_0_1"/>
    <dbReference type="InParanoid" id="G4MZP2"/>
    <dbReference type="OMA" id="MKRDHDK"/>
    <dbReference type="OrthoDB" id="268428at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03758">
        <property type="entry name" value="proteasome_beta_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000008">
        <property type="entry name" value="Proteasome subunit beta type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035206">
        <property type="entry name" value="Proteasome_beta2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="203" mass="22522" checksum="7605C441C279A9D0" modified="2011-12-14" version="1">MEVLLGITGKDFTLIAASKAAMRGATVLKASDDKTRPLNKHTMIAFSGEPGDTIQFAEYIMANAKLYSMRNETDLSPSALAHYVRGELASSLRSRKPYTVNLLLGGVDPITHKPSLYWLDYLAALAPVPYAAHGYAQYYCLSILDKHHHPDITLHQGIKILTMCTDELKRRLPIDFKGMVVKAVTKDGIRDIEFDDDKIVKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0J5</accession>
    <name>G4N0J5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_07727</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712933.1">
        <property type="nucleotide sequence ID" value="XM_003712885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0J5"/>
    <dbReference type="SMR" id="G4N0J5"/>
    <dbReference type="FunCoup" id="G4N0J5">
        <property type="interactions" value="1250"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N0J5"/>
    <dbReference type="GeneID" id="2683654"/>
    <dbReference type="KEGG" id="mgr:MGG_07727"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07727"/>
    <dbReference type="eggNOG" id="KOG0184">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_0_1_1"/>
    <dbReference type="InParanoid" id="G4N0J5"/>
    <dbReference type="OMA" id="RVSMYMH"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03751">
        <property type="entry name" value="proteasome_alpha_type_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000044">
        <property type="entry name" value="Probable proteasome subunit alpha type-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="5">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="277"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="292" mass="31763" checksum="91EFFDCDB0050270" modified="2011-12-14" version="1">MTSIGTGYDLANSIFSPDGRNFQVEYAVKAVENGGTSVGIRCKDGVVLAVEKVVTSKLLKPGANKRIATVDRHLGVAYSGMIPDGRHFVDRARDEARSWRDTFKTPIGTPELASRMGGYLQAYTLYQSVRPFGITAIVAGWDSSLELPVDGEVGVGPSCGAGGKSTDKKYGGPQLYMIEPSGLYWGYYGAATGKGRQAAKAELEKLDLSGDGISLEQAVKEAARIIYVAHDDNKDKEFELEMTWISSEDGPTKGRHEEVPKKLLEEAERLAKKAIEGDDDDDDDKDDEKMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0U3</accession>
    <name>G4N0U3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711333.1">
        <property type="nucleotide sequence ID" value="XM_003711285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0U3"/>
    <dbReference type="GeneID" id="12987032"/>
    <dbReference type="KEGG" id="mgr:MGG_16634"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16634"/>
    <dbReference type="HOGENOM" id="CLU_2146359_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0U3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="112" mass="12957" checksum="4F5CBA12BF9EC53F" modified="2011-12-14" version="1">MEDHQSHRKSLGFCHLIVATNHKKIRRQTNKFTTTRHNVSFAHQSSGEHPSSSVYPPLAKYQNLPFCLASNYGTQFCFSPREMDAQFYPQAQGLQHLSRADRSTQRPYLITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1A7</accession>
    <name>G4N1A7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial 37S ribosomal protein S17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_09556</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712185.1">
        <property type="nucleotide sequence ID" value="XM_003712137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1A7"/>
    <dbReference type="SMR" id="G4N1A7"/>
    <dbReference type="STRING" id="242507.G4N1A7"/>
    <dbReference type="GeneID" id="2680454"/>
    <dbReference type="KEGG" id="mgr:MGG_09556"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09556"/>
    <dbReference type="eggNOG" id="ENOG502SBJ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112095_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1A7"/>
    <dbReference type="OMA" id="VHDPNDS"/>
    <dbReference type="OrthoDB" id="274752at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA52378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="169" mass="18704" checksum="60B4A8210AECD7C3" modified="2011-12-14" version="1">MSEQFVLAARRGFRQIPGVVVSAGLMDRTVKVRVGGRIYNNVIKKHFNRPKTHLVHDPNNSCLTGDVVEISPGWPTSRHKRHVIVSILAAATTPAESRPPVPTLEERIAEAQAKRAAKVERRAAIEAETKAKYAAAAEEKRLRKLKKEGKLPLAEEQQVVKEATETQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1E0</accession>
    <name>G4N1E0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Atypical/PIKK/TRRAP protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_09523</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. TRA1 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA52411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003712170.1"/>
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        <property type="interactions" value="1102"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N1E0"/>
    <dbReference type="GeneID" id="2680478"/>
    <dbReference type="KEGG" id="mgr:MGG_09523"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09523"/>
    <dbReference type="eggNOG" id="KOG0889">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000129_1_0_1"/>
    <dbReference type="InParanoid" id="G4N1E0"/>
    <dbReference type="OMA" id="CLDLYGQ"/>
    <dbReference type="OrthoDB" id="5570127at2759"/>
    <dbReference type="PHI-base" id="PHI:3809"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05163">
        <property type="entry name" value="PIKK_TRRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046807">
        <property type="entry name" value="Tra1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046805">
        <property type="entry name" value="Tra1_ring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF1">
        <property type="entry name" value="TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20175">
        <property type="entry name" value="Tra1_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20206">
        <property type="entry name" value="Tra1_ring"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="6">
        <location>
            <begin position="2664"/>
            <end position="3219"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="5">
        <location>
            <begin position="3504"/>
            <end position="3831"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="7">
        <location>
            <begin position="3829"/>
            <end position="3861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="160"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2026"/>
            <end position="2054"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3228"/>
            <end position="3330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="3238"/>
            <end position="3256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="3270"/>
            <end position="3293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="3294"/>
            <end position="3309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="3310"/>
            <end position="3326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="3861" mass="440722" checksum="C32ECB23B459EE2D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1T1</accession>
    <name>G4N1T1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712253.1">
        <property type="nucleotide sequence ID" value="XM_003712205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1T1"/>
    <dbReference type="GeneID" id="2680562"/>
    <dbReference type="KEGG" id="mgr:MGG_09491"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09491"/>
    <dbReference type="eggNOG" id="ENOG502T4RX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1555579_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1T1"/>
    <dbReference type="OMA" id="TYWDEER"/>
    <dbReference type="OrthoDB" id="5230155at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="172" mass="18788" checksum="8DAE8A24C8E53355" modified="2011-12-14" version="1">MPPFANLVNYTLGRKAEKGNPTDHGTPKTVTYWDEERSENRPECVKCQEILHRGPPCRCNLCGAVNLEVLSDGDASTEKAASADGGKSSSNSNTGKNKNASSSSAAKEEGRLDKDWQHVMVYRPGEEFVPKSQQQVHKNLDKNPNIKTLGKKNQACVICENCIGHKVGLAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1T2</accession>
    <name>G4N1T2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA52447.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_09490"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="5218215at2759"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="2">Uncharacterized protein</fullName>
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            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA53315.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA53315.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2F5</accession>
    <name>G4N2F5_PYRO7</name>
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            <fullName evidence="7">Dihydrodipicolinate synthase</fullName>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the DapA family.</text>
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    <dbReference type="STRING" id="242507.G4N2F5"/>
    <dbReference type="GeneID" id="12986071"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_16966"/>
    <dbReference type="eggNOG" id="ENOG502QWNS">
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    <dbReference type="OMA" id="FHFAMNE"/>
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        <property type="component" value="Chromosome 3"/>
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    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="DHDPS-like"/>
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        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
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    <dbReference type="PANTHER" id="PTHR12128:SF66">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="DHPICSNTHASE"/>
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        <property type="entry name" value="Aldolase"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="3">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="34838" checksum="68A4A45C164237E9" modified="2011-12-14" version="1">MASTTRKPFPHGIHVPSLTWFQDTPAQEIDWAVQKKHFEFLVRSGLHGIVIAGTNGEAATLSAQEKRQLVQTARETAATVGQPLPITLGCGGQTTQQVIAETQLAAEAGADYALVLVPSYFHFAMTEAAILAFFRELADASPIPIIIYNFPGVVAGLDVNSEMLSALGQHPNIIGVKLTCGGIAKVARVSAQFKPDEFFTLAGQSDWLVPAMAVGSVGSITGVANLYPRYCVRIFELFREGKTKEAEQAQLELAKMEWGFGKGGINGTKFIVAKLRGYPLESSHCRRPYPRYESEEKKAWIEGVVRPLEALEKDINENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2H5</accession>
    <name>G4N2H5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_13919</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713187.1">
        <property type="nucleotide sequence ID" value="XM_003713139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2H5"/>
    <dbReference type="SMR" id="G4N2H5"/>
    <dbReference type="GeneID" id="5049413"/>
    <dbReference type="KEGG" id="mgr:MGG_13919"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13919"/>
    <dbReference type="eggNOG" id="ENOG502S0TA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009239_1_0_1"/>
    <dbReference type="InParanoid" id="G4N2H5"/>
    <dbReference type="OMA" id="CAKCISR"/>
    <dbReference type="OrthoDB" id="3037908at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051711">
        <property type="entry name" value="Stress_Response_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540">
        <property type="entry name" value="THIAMINE REPRESSIBLE GENES REGULATORY PROTEIN THI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47540:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="86"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="176"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="670"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA53380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="782" mass="85151" checksum="0439B7A4B78D1171" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N411</accession>
    <name>G4N411_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-acyl-L-amino acid amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_05912</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711740.1">
        <property type="nucleotide sequence ID" value="XM_003711692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N411"/>
    <dbReference type="SMR" id="G4N411"/>
    <dbReference type="GeneID" id="2684063"/>
    <dbReference type="KEGG" id="mgr:MGG_05912"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05912"/>
    <dbReference type="eggNOG" id="ENOG502QQPD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031812_1_1_1"/>
    <dbReference type="InParanoid" id="G4N411"/>
    <dbReference type="OMA" id="GPWEGIN"/>
    <dbReference type="OrthoDB" id="6119954at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05672">
        <property type="entry name" value="M20_ACY1L2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.360:FF:000004">
        <property type="entry name" value="Peptidase M20 domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF4">
        <property type="entry name" value="PEPTIDASE M20 DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465966" evidence="3">
        <location>
            <begin position="26"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="4">
        <location>
            <begin position="232"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA51933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="474" mass="50250" checksum="AE167EF2C3E07C25" modified="2011-12-14" version="1">MVRAHFTSRALLALLVTAIPISACGEEEHFSTLPRRQSAGNSTGVVGGPTTSSPHLATVSEHIDSLAEELWPISTEIHENPELGYEEVRAHDLLTTYVASKPGWEVTRSAFGLDTSFVAVFDGGHGAGPVVSFNAEYDALQGLGHGCGHNLIATASVAGALAAAEVMRRESLPGKVVLFGTPAEESLGGKVRMLEAGAFAEHAIDISIMAHPGPGGDAGDAAYTFAMATDRFDVEYHGQPAHAAASPWLGVNAQDAIALAYAALGLMRQQSRPADRVHGRIATAPGAVNIIPDSAGAVFQIRSDTTENLAPLIERFEKAMEAGALGTGATMNLTMRPYGYSDMLNNDVLARHYREWFDGAIPTADEEKLSGPGGSTDQGNVSHDFPALHAFFGIFGDDGAPATASVHSEGFREAARTRKSFDKALKAAKALAGTAVDVLTVEGLLDEVKEDFEQNNKKDVAQRLARLRRRMIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4N484</accession>
    <name>G4N484_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711759.1">
        <property type="nucleotide sequence ID" value="XM_003711711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N484"/>
    <dbReference type="GeneID" id="12984201"/>
    <dbReference type="KEGG" id="mgr:MGG_16717"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16717"/>
    <dbReference type="HOGENOM" id="CLU_2794439_0_0_1"/>
    <dbReference type="InParanoid" id="G4N484"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="68" mass="8210" checksum="206AAF154071E34A" modified="2011-12-14" version="1">MILLAFWVMPRLQRRRMLSRFPIHGGEHGSHLSRDKVYWTNSEIIYLQAYQKFYNVVHRMTTADGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4S4</accession>
    <name>G4N4S4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712696.1">
        <property type="nucleotide sequence ID" value="XM_003712648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4S4"/>
    <dbReference type="GeneID" id="2675580"/>
    <dbReference type="KEGG" id="mgr:MGG_05161"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05161"/>
    <dbReference type="HOGENOM" id="CLU_573735_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4S4"/>
    <dbReference type="OMA" id="ELANWYE"/>
    <dbReference type="OrthoDB" id="5223211at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="476" mass="53120" checksum="568050182C3B1288" modified="2011-12-14" version="1">MPHNQSSSNFDSLMVAQYLAGRDYQRTFPSKHGSDHGRSLGKPPNIYIVQGPARIETGPVKPRTKSQAWWLPLSLASCLLMLWIGYSLGPQQQHAPYKSQPGIVNAVESTPVGQESSKSYYVAPHPPVFDVFPTVSYPDGVAMDTSTLIGDTKTVLGEDLLSSLEELGFKLNPSKTYPEKEAAKLPEQLRHLGQLTDLSLKRSLLRTQWLQTQCRITPSSRWITEAEQYRNSTGRYEPLPWWCVSRHLPLEACLDAATKAHLDIEARLWTLGSSLIQASSDMTIVVDDSARTKLDRTIADAREEACGQADRLSRLFDRLVGGIAVWRERHQGPEHKTLRIAPSAGHTGWDGVPNAWYITAHDETDLQTRGADLRVKVEDLDELQTKGSGIAARGRKTCSSAQKVEEQLAVALGEKIPAYRKFLEAEIRMVGEWQQRLREEGHGGFQGPAGIELANWYEAQIGISTTRWEKAIEAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4X0</accession>
    <name>G4N4X0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Histidinol-phosphatase</fullName>
            <shortName evidence="8">HolPase</shortName>
            <ecNumber evidence="3 8">3.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_06040</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-histidinol phosphate + H2O = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PHP hydrolase family. HisK subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="3 8"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711889.1">
        <property type="nucleotide sequence ID" value="XM_003711841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4X0"/>
    <dbReference type="SMR" id="G4N4X0"/>
    <dbReference type="FunCoup" id="G4N4X0">
        <property type="interactions" value="112"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N4X0"/>
    <dbReference type="GeneID" id="2683935"/>
    <dbReference type="KEGG" id="mgr:MGG_06040"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06040"/>
    <dbReference type="eggNOG" id="ENOG502RXUQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054611_0_1_1"/>
    <dbReference type="InParanoid" id="G4N4X0"/>
    <dbReference type="OMA" id="DYDRPMY"/>
    <dbReference type="OrthoDB" id="5957391at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12110">
        <property type="entry name" value="PHP_HisPPase_Hisj_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010140">
        <property type="entry name" value="Histidinol_P_phosphatase_HisJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01856">
        <property type="entry name" value="hisJ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039">
        <property type="entry name" value="HISTIDINOL PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039:SF0">
        <property type="entry name" value="HISTIDINOL-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHP" evidence="9">
        <location>
            <begin position="5"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="333" mass="37225" checksum="D7A163015CF788A1" modified="2011-12-14" version="1">MAFTMHSHSGQFCPGHAKDQLEDVILHAISIGYKTMGLSEHMPRTQLCDLYPEELVPDPHASLAELMPRHAAYMTEARRLQKKYADRITLLIGFEGEFIRSEYGTLVRSLADGNGDPSYFQNGDSKLVTDAGKVDYFIGSLHHGAGGIPIDFDRATYLRSVEAAGPNGEEDLFVHYYDQQFEMLQALRPPIVGHFDLIRLMSEEPGRNPSAWSPNRVWPLIKRNLAFVASYGGWLECNSSALRKGLAEPYPCRPIAEEWVRLGGKFTMSDDSHGIAQVATNYVRALDYLESLGVNEVWTYDRAKEGSELVEKGVSFTEFRGSLRLPTTASKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N510</accession>
    <name>G4N510_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712728.1">
        <property type="nucleotide sequence ID" value="XM_003712680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N510"/>
    <dbReference type="GeneID" id="2675703"/>
    <dbReference type="KEGG" id="mgr:MGG_05186"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05186"/>
    <dbReference type="eggNOG" id="ENOG502RAIS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1603064_0_0_1"/>
    <dbReference type="InParanoid" id="G4N510"/>
    <dbReference type="OMA" id="LSRTWTW"/>
    <dbReference type="OrthoDB" id="4825861at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="166" mass="17825" checksum="8F59BE1186351536" modified="2011-12-14" version="1">MSIRNTWNRMMRRTSTGSTTSSSSSNSDSMSPASTAPSSPGWGPSATFSWLVPSSSKSSNGSSGLSSPTSAPVVATQPLPHSKSDKEKKKSKKSYYSSTSSSAHKKRVHPSERPLTKENLRHQELFANFSFAEPGGSSCNRGFSSRHSYESGISPCSSRRNSFAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5E6</accession>
    <name>G4N5E6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CrcB-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_05253</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>fluoride(in) = fluoride(out)</text>
            <dbReference type="Rhea" id="RHEA:76159"/>
            <dbReference type="ChEBI" id="CHEBI:17051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:76160"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712810.1">
        <property type="nucleotide sequence ID" value="XM_003712762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5E6"/>
    <dbReference type="SMR" id="G4N5E6"/>
    <dbReference type="FunCoup" id="G4N5E6">
        <property type="interactions" value="121"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5E6"/>
    <dbReference type="GeneID" id="2675468"/>
    <dbReference type="KEGG" id="mgr:MGG_05253"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05253"/>
    <dbReference type="eggNOG" id="ENOG502QT5F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030507_1_1_1"/>
    <dbReference type="InParanoid" id="G4N5E6"/>
    <dbReference type="OMA" id="CYDLQHV"/>
    <dbReference type="OrthoDB" id="409792at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="FluC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259:SF1">
        <property type="entry name" value="FLUORIDE EXPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="38484" checksum="2C1336C1F6C54BC4" modified="2011-12-14" version="1">MSTSPQPPSRQGDKRPAVFSARTSTELYTISYLILFSLLGTLARLGLQALTTYPGSPVLFPSVWPNLGGSFVIGFLAEDRSLFRARRQEQEEQDHQKYKKTIPLYIGLATGFCGSFTSFSSFIRDVVLTLTNDLGPDPAISGPAPRNGGFSFMAFLAVIIVTVSLSLCALVAGAHFALALQPLLPSVMGSERLRKAMDLSVIILGWGCWIAACLVAGFAPSEVWRGQVLFALVFAPLGCLARFYLSLALNGKLTPSFPVGTFTVNVVGTVVLAVCWDIAHAGAGGIIGCQVLQGLEDGFCGCLTTVSTWVAELVGLAAKRRRDAYIYGATSVVAALAVGIAIMGGFRWSHDSLPELLCVIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5F3</accession>
    <name>G4N5F3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA biogenesis protein RRP5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ribosomal RNA-processing protein 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_05260</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the biogenesis of rRNA. Required for the formation of 18S and 5.8S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712817.1">
        <property type="nucleotide sequence ID" value="XM_003712769.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N5F3"/>
    <dbReference type="FunCoup" id="G4N5F3">
        <property type="interactions" value="1092"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5F3"/>
    <dbReference type="GeneID" id="2675326"/>
    <dbReference type="KEGG" id="mgr:MGG_05260"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05260"/>
    <dbReference type="eggNOG" id="KOG1070">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000845_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5F3"/>
    <dbReference type="OMA" id="GQYLRAY"/>
    <dbReference type="OrthoDB" id="412781at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05702">
        <property type="entry name" value="S1_Rrp5_repeat_hs11_sc8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05693">
        <property type="entry name" value="S1_Rrp5_repeat_hs1_sc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05694">
        <property type="entry name" value="S1_Rrp5_repeat_hs2_sc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05696">
        <property type="entry name" value="S1_Rrp5_repeat_hs4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05697">
        <property type="entry name" value="S1_Rrp5_repeat_hs5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05698">
        <property type="entry name" value="S1_Rrp5_repeat_hs6_sc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04461">
        <property type="entry name" value="S1_Rrp5_repeat_hs8_sc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05706">
        <property type="entry name" value="S1_Rrp5_repeat_sc10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05708">
        <property type="entry name" value="S1_Rrp5_repeat_sc12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000103">
        <property type="entry name" value="protein RRP5 homolog"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000467">
        <property type="entry name" value="Putative rRNA biogenesis protein RRP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000155">
        <property type="entry name" value="rRNA biogenesis protein RRP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000159">
        <property type="entry name" value="rRNA biogenesis protein rrp5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000196">
        <property type="entry name" value="rRNA biogenesis protein RRP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000266">
        <property type="entry name" value="rRNA biogenesis protein rrp5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000279">
        <property type="entry name" value="rRNA biogenesis protein rrp5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045209">
        <property type="entry name" value="Rrp5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057301">
        <property type="entry name" value="Rrp5_OB_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057302">
        <property type="entry name" value="Rrp5_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048058">
        <property type="entry name" value="Rrp5_S1_rpt_hs11_sc8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048059">
        <property type="entry name" value="Rrp5_S1_rpt_hs1_sc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23270">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23270:SF10">
        <property type="entry name" value="PROTEIN RRP5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24685">
        <property type="entry name" value="OB_RRP5_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23459">
        <property type="entry name" value="S1_RRP5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="S1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
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        <location>
            <begin position="138"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="250"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="437"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="529"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="623"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="711"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="807"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="908"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="1011"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="1103"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="1197"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="1286"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1360"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1362"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1386"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1417"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1431"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1455"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1478"/>
            <end position="1487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00055575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00073619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00076674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA53010.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1781" mass="194242" checksum="9064DC90F452BD72" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6G6</accession>
    <name>G4N6G6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">COP9 signalosome complex subunit 7a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_03725</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716155.1">
        <property type="nucleotide sequence ID" value="XM_003716107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6G6"/>
    <dbReference type="SMR" id="G4N6G6"/>
    <dbReference type="STRING" id="242507.G4N6G6"/>
    <dbReference type="GeneID" id="2676666"/>
    <dbReference type="KEGG" id="mgr:MGG_03725"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03725"/>
    <dbReference type="eggNOG" id="KOG3250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054426_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6G6"/>
    <dbReference type="OMA" id="GTYKQFR"/>
    <dbReference type="OrthoDB" id="10265275at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF5">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22061">
        <property type="entry name" value="CSN7_HB_subdom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="220"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA49836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="286" mass="30782" checksum="8C294971526B01D4" modified="2011-12-14" version="1">MEQAKALNALEPFLALSKAATAPRAAADLVLQATSAPNTFIFTELLAQPEIQALVTSADYSPALTVLQVFSYGTWATYAQTPGLPPLNDAQALKLRQLSLLTMARDKDALKYDVLMSGLQLQTKSELESLVVSAVYAGLITAKLDPAHGIVRVSSVSPLRDLAPGTVPDLINELHQWYDRCRSALDDLDAEIATIRQTAATRVTEKSEWDSKMQRLIEDEKNATDSGGGGTSSSRKLPTGLGSGRRLGFGKRANVGSMADAGDEAMDVDTDDDDSNTKKRSSRRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2024-01-24" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6N7</accession>
    <name>G4N6N7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717025.1">
        <property type="nucleotide sequence ID" value="XM_003716977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6N7"/>
    <dbReference type="GeneID" id="12985531"/>
    <dbReference type="KEGG" id="mgr:MGG_17175"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17175"/>
    <dbReference type="InParanoid" id="G4N6N7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="212" mass="23740" checksum="53A357B98E1C69F3" modified="2011-12-14" version="1" fragment="single">IRCPPRKNYHVPETFRAETSCSGPESPDGDFRYVLIVHQAPVSCAYLCPSSSHLLLYFSFVFGGLQLGETTDCTRECGIAGPEKKVAAEYRKTSDLGITMERARNGPLDWLARWILTQEKAVKLESRCQELVSKRKIYRAYRISDGPNELMVLFQPCGVSDPTDPHLLARPLVTSTVGQPKGKPIGIFNIETDNLRTLERRGALKVAKWPMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6T3</accession>
    <name>G4N6T3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="7">2.3.3.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_13485</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="7"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716219.1">
        <property type="nucleotide sequence ID" value="XM_003716171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6T3"/>
    <dbReference type="SMR" id="G4N6T3"/>
    <dbReference type="FunCoup" id="G4N6T3">
        <property type="interactions" value="180"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N6T3"/>
    <dbReference type="GeneID" id="5051642"/>
    <dbReference type="KEGG" id="mgr:MGG_13485"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13485"/>
    <dbReference type="eggNOG" id="KOG2367">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004588_3_0_1"/>
    <dbReference type="InParanoid" id="G4N6T3"/>
    <dbReference type="OMA" id="WPDKVID"/>
    <dbReference type="OrthoDB" id="418791at2759"/>
    <dbReference type="PHI-base" id="PHI:9356"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07942">
        <property type="entry name" value="DRE_TIM_LeuA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.270:FF:000002">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00572">
        <property type="entry name" value="LeuA_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005668">
        <property type="entry name" value="IPM_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054692">
        <property type="entry name" value="LeuA-like_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039371">
        <property type="entry name" value="LeuA_N_DRE-TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00970">
        <property type="entry name" value="leuA_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002991">
        <property type="entry name" value="PRK03739.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46911">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46911:SF1">
        <property type="entry name" value="2-ISOPROPYLMALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22615">
        <property type="entry name" value="IPMS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89000">
        <property type="entry name" value="post-HMGL domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="14">
        <location>
            <begin position="33"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA49900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="616" mass="67960" checksum="EED244C9016213FF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N723</accession>
    <name>G4N723_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">F-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_13493</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716255.1">
        <property type="nucleotide sequence ID" value="XM_003716207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N723"/>
    <dbReference type="SMR" id="G4N723"/>
    <dbReference type="FunCoup" id="G4N723">
        <property type="interactions" value="115"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N723"/>
    <dbReference type="GeneID" id="5051647"/>
    <dbReference type="KEGG" id="mgr:MGG_13493"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13493"/>
    <dbReference type="eggNOG" id="KOG2997">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017706_0_0_1"/>
    <dbReference type="InParanoid" id="G4N723"/>
    <dbReference type="OMA" id="SWSQVFQ"/>
    <dbReference type="OrthoDB" id="2117972at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045464">
        <property type="entry name" value="Hrt3/FBXO9_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19270">
        <property type="entry name" value="FBO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="245"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="172"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="560" mass="62210" checksum="E4C9DFB45FE98A69" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7U9</accession>
    <name>G4N7U9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717222.1">
        <property type="nucleotide sequence ID" value="XM_003717174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7U9"/>
    <dbReference type="GeneID" id="12985610"/>
    <dbReference type="KEGG" id="mgr:MGG_17189"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17189"/>
    <dbReference type="HOGENOM" id="CLU_2413687_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7U9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="92" mass="10557" checksum="6FDE9451810B4F8C" modified="2011-12-14" version="1">MGFVLKSTLISARHFKLEQEPYHEHHTDQLPVHLGYSHRYGPLLRLRRRPPCSGCPVDSAHPKLVLSIARLTFSKTARLSNSWKTAAKRPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7X3</accession>
    <name>G4N7X3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_06336</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717246.1">
        <property type="nucleotide sequence ID" value="XM_003717198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7X3"/>
    <dbReference type="STRING" id="242507.G4N7X3"/>
    <dbReference type="GeneID" id="2684491"/>
    <dbReference type="KEGG" id="mgr:MGG_06336"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06336"/>
    <dbReference type="eggNOG" id="KOG3912">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025028_3_1_1"/>
    <dbReference type="InParanoid" id="G4N7X3"/>
    <dbReference type="OMA" id="FIYKHNV"/>
    <dbReference type="OrthoDB" id="29773at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012404">
        <property type="entry name" value="UCP036436"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036436">
        <property type="entry name" value="UCP036436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465903" evidence="6">
        <location>
            <begin position="23"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="428" mass="46914" checksum="FADB9FB4D012DA6C" modified="2011-12-14" version="1">MASRAMVPFLVAMMLLTGVCNTLLTKYQDNQCVRNCEDPDPKKRVHFEQPVIQTAQMFVGEMGCWLVIGLMSLRERYMARKQAAGYEAVRSSDDVPDADDASVHSTTALNGTGAGKPVHAHDSMLAGIRVFLLAIPAICDICGTTLMNAGLLMVAASIYQMTRGALVLFVGLFSVVFLRRRLHLFQWLSLVGVVTGVAIVGLAGAIYPDKAKPGSPHSEVVPTSTPFQAASTAEGGLDANALRAVVGVLLIAGAQIFTATQFVVEEWLLERSTIEPIRVVGWEGIFGFSVTVLGMIVMHLAIGRTETGKYGYFDMVEGWRQMVENPRVLISSVLIMISIGGFNFFGLSVTRTVSATSRSTIDTCRTLFIWIVSLGLGWETFKWLQVLGFGFLVYFTFLFNGIVQPPFKFLQVDEEIEELLPEEPVEHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N873</accession>
    <name>G4N873_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Large ribosomal subunit protein mL60</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the mitochondrial large ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717293.1">
        <property type="nucleotide sequence ID" value="XM_003717245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N873"/>
    <dbReference type="SMR" id="G4N873"/>
    <dbReference type="FunCoup" id="G4N873">
        <property type="interactions" value="72"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N873"/>
    <dbReference type="GeneID" id="2684450"/>
    <dbReference type="KEGG" id="mgr:MGG_06295"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06295"/>
    <dbReference type="eggNOG" id="ENOG502S81F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141719_0_0_1"/>
    <dbReference type="InParanoid" id="G4N873"/>
    <dbReference type="OMA" id="KYTVFDR"/>
    <dbReference type="OrthoDB" id="2332379at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016340">
        <property type="entry name" value="Ribosomal_mL60"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28271">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L31, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28271:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09784">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002216">
        <property type="entry name" value="MRPL31_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR002216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="110" mass="13116" checksum="1477AC8E7DFF11DA" modified="2011-12-14" version="1">MFGPFRITNVLNGGLLWKTPWRLSRFQKLRQRRRLRAVDDVVATLDKALAKKGESLKSLERWKEEMPTEAEMAPRDKYTIFARYEKKYRKGIHKLPKWTRVSQRVNPPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8Q3</accession>
    <name>G4N8Q3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CobW domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717368.1">
        <property type="nucleotide sequence ID" value="XM_003717320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8Q3"/>
    <dbReference type="STRING" id="242507.G4N8Q3"/>
    <dbReference type="GeneID" id="2684377"/>
    <dbReference type="KEGG" id="mgr:MGG_06222"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06222"/>
    <dbReference type="eggNOG" id="KOG2743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_2_1_1"/>
    <dbReference type="InParanoid" id="G4N8Q3"/>
    <dbReference type="OMA" id="WSQAGPN"/>
    <dbReference type="OrthoDB" id="272672at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051927">
        <property type="entry name" value="Zn_Chap_cDPG_Synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43603:SF1">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="319"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="546" mass="60948" checksum="226FB023622D97F9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N986</accession>
    <name>G4N986_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716649.1">
        <property type="nucleotide sequence ID" value="XM_003716601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N986"/>
    <dbReference type="SMR" id="G4N986"/>
    <dbReference type="STRING" id="242507.G4N986"/>
    <dbReference type="GeneID" id="2676457"/>
    <dbReference type="KEGG" id="mgr:MGG_03311"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03311"/>
    <dbReference type="eggNOG" id="ENOG502QRFX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_42_5_1"/>
    <dbReference type="InParanoid" id="G4N986"/>
    <dbReference type="OMA" id="EMLIEHD"/>
    <dbReference type="OrthoDB" id="10264707at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052742">
        <property type="entry name" value="Mito_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015416">
        <property type="entry name" value="Znf_H2C2_histone_UAS-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43138">
        <property type="entry name" value="ACETYLTRANSFERASE, GNAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43138:SF2">
        <property type="entry name" value="PROTEIN SPT10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09337">
        <property type="entry name" value="zf-H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="79"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="659"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="715" mass="78736" checksum="C4E8E3DEF1A037A9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9G7</accession>
    <name>G4N9G7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase PEP5</fullName>
            <ecNumber evidence="9">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_03283</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Vacuole membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the VPS11 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="9"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716678.1">
        <property type="nucleotide sequence ID" value="XM_003716630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9G7"/>
    <dbReference type="SMR" id="G4N9G7"/>
    <dbReference type="FunCoup" id="G4N9G7">
        <property type="interactions" value="583"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9G7"/>
    <dbReference type="GeneID" id="2676718"/>
    <dbReference type="KEGG" id="mgr:MGG_03283"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03283"/>
    <dbReference type="eggNOG" id="KOG2114">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001287_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9G7"/>
    <dbReference type="OMA" id="ENENECP"/>
    <dbReference type="OrthoDB" id="26184at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033263">
        <property type="term" value="C:CORVET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16688">
        <property type="entry name" value="RING-H2_Vps11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000440">
        <property type="entry name" value="E3 ubiquitin-protein ligase PEP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057308">
        <property type="entry name" value="CHCR_PEP5_VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057307">
        <property type="entry name" value="PEP5_VPS11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016528">
        <property type="entry name" value="VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024763">
        <property type="entry name" value="VPS11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF24">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23341">
        <property type="entry name" value="PEP5_VPS11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23356">
        <property type="entry name" value="TPR_PEP5_VPS11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12451">
        <property type="entry name" value="VPS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007860">
        <property type="entry name" value="VPS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0926">Vacuole</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="CHCR" evidence="11">
        <location>
            <begin position="420"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="906"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR007860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA50359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1008" mass="112151" checksum="76B7D2C4D3D5B6A8" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9Z6</accession>
    <name>G4N9Z6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717561.1">
        <property type="nucleotide sequence ID" value="XM_003717513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9Z6"/>
    <dbReference type="SMR" id="G4N9Z6"/>
    <dbReference type="STRING" id="242507.G4N9Z6"/>
    <dbReference type="GeneID" id="2680730"/>
    <dbReference type="KEGG" id="mgr:MGG_09783"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09783"/>
    <dbReference type="eggNOG" id="ENOG502SZDW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158824_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9Z6"/>
    <dbReference type="OMA" id="YREAQMQ"/>
    <dbReference type="OrthoDB" id="4338954at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="108" mass="12022" checksum="6C829296CDA65BEE" modified="2011-12-14" version="1">MPSSSTAQQTSRHFATSSRVHPSYLPYLQAPKPPKVAKWIPPAVAIAGIGYGVTKFQQSRSLRSAAQKADEADRKRRNDLMADAYGDRGSLEALEEACRVYESQQQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA55</accession>
    <name>G4NA55_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715924.1">
        <property type="nucleotide sequence ID" value="XM_003715876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA55"/>
    <dbReference type="GeneID" id="12986819"/>
    <dbReference type="KEGG" id="mgr:MGG_17011"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17011"/>
    <dbReference type="HOGENOM" id="CLU_2469532_0_0_1"/>
    <dbReference type="InParanoid" id="G4NA55"/>
    <dbReference type="OrthoDB" id="10436630at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="88" mass="9533" checksum="DF957A366E890DE8" modified="2011-12-14" version="1">MAISRHGPKRDRFPISHAVVCQLHGPFECAVAPRKCQLDRLNTPGAPSPKVPDGAESRPPVVGQSAGGLWNHSDDCREKRKMGPKLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB71</accession>
    <name>G4NB71_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Lactoylglutathione lyase</fullName>
            <ecNumber evidence="3 9">4.4.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glyoxalase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_11543</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-S-lactoylglutathione = methylglyoxal + glutathione</text>
            <dbReference type="Rhea" id="RHEA:19069"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="ChEBI" id="CHEBI:57474"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="4.4.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glyoxalase I family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.5" evidence="3 9"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718417.1">
        <property type="nucleotide sequence ID" value="XM_003718369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB71"/>
    <dbReference type="SMR" id="G4NB71"/>
    <dbReference type="FunCoup" id="G4NB71">
        <property type="interactions" value="214"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NB71"/>
    <dbReference type="GeneID" id="5050700"/>
    <dbReference type="KEGG" id="mgr:MGG_11543"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11543"/>
    <dbReference type="eggNOG" id="KOG2944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_0_1_1"/>
    <dbReference type="InParanoid" id="G4NB71"/>
    <dbReference type="OMA" id="MGDAWGH"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07233">
        <property type="entry name" value="GlxI_Zn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004361">
        <property type="entry name" value="Glyoxalase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00068">
        <property type="entry name" value="glyox_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374:SF30">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE GLYOXALASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00935">
        <property type="entry name" value="GLYOXALASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="VOC" evidence="10">
        <location>
            <begin position="53"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="10">
        <location>
            <begin position="212"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604361-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR604361-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA48833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="357" mass="40781" checksum="C519212B14B67545" modified="2011-12-14" version="1">MNSSRIVQRLRLQASHLQPSRAIGARLSPPSTSQRHPRSLATMAATTDPKKYKFNHSMIRVKDPRESVKFYELLGMSVIQKFEFPEAKFDLYFMAYDSPKAKSGGNNFTDREGIIELTHNYGTEADASYTVNNGNKEPHRGFGHTCISVDNIQAACKRIEDAGYMFQKKLTDGRMRHIAFVLDPDGYWVEVIGQKSIEETENVTTTDVQTYRMNHTMIRVKDAEKSLKFYQEVLGMKLLKENANPDNGFTLFFLGYEQSGPHSADREGLLELTWNHGTEKDENFSYHNGNDQPQGFGHICISVDNLDAACQRLEDLKVNWKKRLTDGRMKNVAFVLDPDNYWVEIVENEKLSGKSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCB2</accession>
    <name>G4NCB2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cercosporin toxin biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00427</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718645.1">
        <property type="nucleotide sequence ID" value="XM_003718597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCB2"/>
    <dbReference type="SMR" id="G4NCB2"/>
    <dbReference type="GeneID" id="2674893"/>
    <dbReference type="KEGG" id="mgr:MGG_00427"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00427"/>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_370883_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCB2"/>
    <dbReference type="OMA" id="TEEWHPS"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF19">
        <property type="entry name" value="DUAL O-METHYLTRANSFERASE_FAD-DEPENDENT MONOOXYGENASE ELCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="7">
        <location>
            <begin position="192"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="8">
        <location>
            <begin position="791"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="872" mass="96826" checksum="0493F346DA9E0C47" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCF6</accession>
    <name>G4NCF6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718689.1">
        <property type="nucleotide sequence ID" value="XM_003718641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCF6"/>
    <dbReference type="GeneID" id="2675102"/>
    <dbReference type="KEGG" id="mgr:MGG_00387"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00387"/>
    <dbReference type="HOGENOM" id="CLU_1049995_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCF6"/>
    <dbReference type="OMA" id="DDNCANA"/>
    <dbReference type="OrthoDB" id="5215637at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="265" mass="28326" checksum="16FB66A26F56E5FB" modified="2011-12-14" version="1">MAAVVAPRVKQHRAACLSNGLCLDQKTNSRLRRMSCADPALLPQNCPAIDLCRGESPGSPGILRQCPKDETYWFCLRPDVWDDNCANASMTLKAGRVDDGRNGNLSGILLAGEVNVCQTDVPAAQEAPAASSSSSSSQDSTIAVGVSLGVLLLAAAAVAFFFWRRWKDMRLELDAFRAGMNTTSPPETQKRHPSLKRVPSVAEVAFPDDRSELPQTGPSPGSEIHEADAGQVFEVHGTSKHTPSTIAASPRLPPTLASSPRITLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCK7</accession>
    <name>G4NCK7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">PET8 related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_01051</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717888.1">
        <property type="nucleotide sequence ID" value="XM_003717840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCK7"/>
    <dbReference type="SMR" id="G4NCK7"/>
    <dbReference type="FunCoup" id="G4NCK7">
        <property type="interactions" value="738"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NCK7"/>
    <dbReference type="GeneID" id="2674735"/>
    <dbReference type="KEGG" id="mgr:MGG_01051"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01051"/>
    <dbReference type="eggNOG" id="KOG0768">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_3_0_1"/>
    <dbReference type="InParanoid" id="G4NCK7"/>
    <dbReference type="OMA" id="IGPRTMW"/>
    <dbReference type="OrthoDB" id="276989at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000112">
        <property type="entry name" value="Mitochondrial carrier protein (Pet8), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="94"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="203"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA48304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="30961" checksum="03C89C55C18CA9B2" modified="2011-12-14" version="1">MSPTDASPPFRHALLAGALAGTTVDMSLFPLDTLKTRLQSSAGFFPSGGFRGVYKGIGSAFWGSAPGAALFFVTYEGIKSSKALSSLSSPTTGNPAATHMLAASLGEIAACAVRVPTEVVKQRAQAGQHGGRSMAALASILATRHGAGGLVGVWRELYRGWGITVFREVPFTVIQFPLWEALKAWGRDRRDRGVTIGGPQPDVGAAESALYGSVSGAVAAAVTTPLDVLKTRVMLSREREGVLSITKNILREHGVKPFFSGIGPRVAWISAGGAIFLGSYQWAINCFATGTLAVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND53</accession>
    <name>G4ND53_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717979.1">
        <property type="nucleotide sequence ID" value="XM_003717931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND53"/>
    <dbReference type="SMR" id="G4ND53"/>
    <dbReference type="STRING" id="242507.G4ND53"/>
    <dbReference type="GeneID" id="2675019"/>
    <dbReference type="KEGG" id="mgr:MGG_00971"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00971"/>
    <dbReference type="eggNOG" id="KOG3133">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043063_1_1_1"/>
    <dbReference type="InParanoid" id="G4ND53"/>
    <dbReference type="OMA" id="YEPMKEM"/>
    <dbReference type="OrthoDB" id="21292at2759"/>
    <dbReference type="PHI-base" id="PHI:4084"/>
    <dbReference type="PHI-base" id="PHI:9785"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033328">
        <property type="term" value="F:peroxisome membrane targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.900">
        <property type="entry name" value="Pex19, mPTS binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006708">
        <property type="entry name" value="Pex19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038322">
        <property type="entry name" value="Pex19_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774:SF2">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04614">
        <property type="entry name" value="Pex19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="338" mass="36011" checksum="092E10DF32EA8ACF" modified="2011-12-14" version="1">MADRPEDTAPIKDAPAPAVAAPASEPTTAAPEAPKVAEVVEDVPDPDEDDLDDLDDMLDEFSAVKLNPPKTPHVSAPGPSEPSAAPPLPTSKPPATDGADEFDEDEFAKQLQAGMAEMLGDMGSSPEMQAQFESIFKELGAAAAADESSNPSAGAPPPASSSSFQDNIRRTMERMQASGDSATAAATADSNAEDDFMAELLKQMQGGGAGAGLGGEGGEEEFSKMLLGMMEQLTNKEILYEPMKELHDKFPEWLERNKDKTSAEDLKRYEEQQRLVSEMVVKFEEPTYLDSNAADREYIVDRMQKMQATGSPPSDLVGDMPSAQEALGAPDPEACTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDR6</accession>
    <name>G4NDR6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA primase</fullName>
            <ecNumber evidence="9">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_00881</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic-type primase small subunit family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003718040.1"/>
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    <dbReference type="FunCoup" id="G4NDR6">
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    <dbReference type="KEGG" id="mgr:MGG_00881"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00881"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_028288_1_0_1"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="DNA primase, PRIM domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="primase_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10536">
        <property type="entry name" value="DNA PRIMASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01896">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56747">
        <property type="entry name" value="Prim-pol domain"/>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="2 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="3 9" id="KW-0639">Primosome</keyword>
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    <feature type="region of interest" description="Disordered" evidence="10">
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            <begin position="1"/>
            <end position="105"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA48504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="4">Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A</fullName>
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        <name evidence="4" type="ORF">MGG_00799</name>
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    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718187.1">
        <property type="nucleotide sequence ID" value="XM_003718139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEC0"/>
    <dbReference type="GeneID" id="2674430"/>
    <dbReference type="KEGG" id="mgr:MGG_00799"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00799"/>
    <dbReference type="eggNOG" id="ENOG502QSXK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011027_0_1_1"/>
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    <dbReference type="OMA" id="KFNRVVM"/>
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        <property type="component" value="Chromosome 5"/>
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    <dbReference type="InterPro" id="IPR021102">
        <property type="entry name" value="PNGase_A"/>
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        <property type="entry name" value="PNGaseA_N"/>
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    <dbReference type="PANTHER" id="PTHR31104">
        <property type="entry name" value="PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE A PROTEIN"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF25156">
        <property type="entry name" value="PNGase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PNGaseA"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A N-terminal" evidence="3">
        <location>
            <begin position="165"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NER3</accession>
    <name>G4NER3_PYRO7</name>
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        <recommendedName>
            <fullName evidence="3">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_17542</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719070.1">
        <property type="nucleotide sequence ID" value="XM_003719022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NER3"/>
    <dbReference type="SMR" id="G4NER3"/>
    <dbReference type="STRING" id="242507.G4NER3"/>
    <dbReference type="GeneID" id="12985137"/>
    <dbReference type="KEGG" id="mgr:MGG_17542"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17542"/>
    <dbReference type="eggNOG" id="ENOG502SFG8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_4_0_1"/>
    <dbReference type="InParanoid" id="G4NER3"/>
    <dbReference type="OMA" id="WCGGLCW"/>
    <dbReference type="OrthoDB" id="5340195at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF289">
        <property type="entry name" value="GLYCINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="3">
        <location>
            <begin position="49"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="408" mass="42889" checksum="6006D9C4B8683677" modified="2011-12-14" version="1">MTSRSSERTCATTAQNHNPPPTPEQPPAANPDTKTKEMAAAAAAAPPAHVAVVGGGIMGASIAWHLSQHTNVTVIAPDVGGVATRASFAWLNAASGEDRAYYDFRRRSVGRWRELEAQIPGLPVHWGGGFKWDLPPDELADFADKFAGWGYDIIRVDRSGIERMEPRVDPAVVPDWALYSPEEGALEADAAARLMVQHAVARGSAEVVEGTVAGFARTGGGGGVSGVVLEGGGTIEADHVVVAAGLGSVALLAAEGVDVPVAGRAGLLVNTKPLADRIASSVVYTSLLHLRQTLDGVVRVGLNEERITEDPDGDAEVVLAALREAVAQGGELELDYYTVGERPVPEDGRPIIGATGVEGVSLAVMHSGVTNAALVGELLSREILTGERDPMLDDYLLERFRKRVKLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NES8</accession>
    <name>G4NES8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">R-specific carbonyl reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_00057</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719085.1">
        <property type="nucleotide sequence ID" value="XM_003719037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NES8"/>
    <dbReference type="SMR" id="G4NES8"/>
    <dbReference type="STRING" id="242507.G4NES8"/>
    <dbReference type="GeneID" id="2675055"/>
    <dbReference type="KEGG" id="mgr:MGG_00057"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00057"/>
    <dbReference type="eggNOG" id="KOG0022">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_2_1"/>
    <dbReference type="InParanoid" id="G4NES8"/>
    <dbReference type="OMA" id="CERGHHS"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08254">
        <property type="entry name" value="hydroxyacyl_CoA_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42940:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="13"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA49501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="274" mass="29584" checksum="05A8BEB60BB443BC" modified="2011-12-14" version="1">MGKDTKEAKVKVGDLVALYAVPGCGAGDCPECSRDLPQICEVGHHSGVGQDGFYAPYAHVDIRGVVPVPDGVSPAQAAVATDAINTAFHAITRRAEVQPHETVFLFGLGGLGFNALQVVRHIGARVLVKDVKQSRVDDARDIGVPPEDIAPLDVTVDEFVARRGLHVDTVLDFVGAHDTFDAAQRIVRRGGKILCVGSLDTENTVSMKIGTRKRLSFIFSYAGQVQDLEKVLDLVARGVIRPQVQEKRLKDFPDVVRDLEAGKIDGRVALMQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFU0</accession>
    <name>G4NFU0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719264.1">
        <property type="nucleotide sequence ID" value="XM_003719216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFU0"/>
    <dbReference type="STRING" id="242507.G4NFU0"/>
    <dbReference type="GeneID" id="2679022"/>
    <dbReference type="KEGG" id="mgr:MGG_08715"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08715"/>
    <dbReference type="HOGENOM" id="CLU_1865502_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFU0"/>
    <dbReference type="OMA" id="RVSIFIT"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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</entry>
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            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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    </reference>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Mitchell T.K."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
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                <person name="Bohnert H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Young S.K."/>
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                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
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                <person name="Dunbar C."/>
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                <person name="Gearin G."/>
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                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
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                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Read N.D."/>
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                <person name="Soanes D.M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
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                <person name="MacDonald P.J.P."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    <dbReference type="OrthoDB" id="18595at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039603">
        <property type="entry name" value="Ribosomal_mS41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019083">
        <property type="entry name" value="SAM_Ribosomal_mS41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28235">
        <property type="entry name" value="PROTEIN FYV4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28235:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09597">
        <property type="entry name" value="SAM_Ribosomal_mS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01238">
        <property type="entry name" value="IGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS41 SAM" evidence="5">
        <location>
            <begin position="53"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA47456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="235" mass="26607" checksum="DA232F9FFD9C70A0" modified="2011-12-14" version="1">MPPSKTFSFLSSLLRSRPTTASIPSISPAIQSRWVSSKRTFTIPEPIPLVPDVPTFLRLIGRDLVKHASKFPSWEALFSLTPPQLRELGIEPARSRRYLISWRNKYTQGHFGIGGDLKHVVDGAAELKVLNIPKGPLKTHRVVVNVPPGTKPEDVPEKERPRIQGYKVIGTRTIAGPHAVPMKNHEGSIFKAVDGLWEHKRGRKIDGGERRRAEVRFKRRVEERKAMRESQGFNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI35</accession>
    <name>G4NI35_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine zipper 2TM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720262.1">
        <property type="nucleotide sequence ID" value="XM_003720214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI35"/>
    <dbReference type="STRING" id="242507.G4NI35"/>
    <dbReference type="GeneID" id="2680427"/>
    <dbReference type="KEGG" id="mgr:MGG_09361"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09361"/>
    <dbReference type="eggNOG" id="ENOG502RUDN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1046124_0_0_1"/>
    <dbReference type="InParanoid" id="G4NI35"/>
    <dbReference type="OMA" id="GWAGNKM"/>
    <dbReference type="OrthoDB" id="10638905at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014">
        <property type="entry name" value="EXPRESSION LETHALITY PROTEIN HEL10, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37014:SF10">
        <property type="entry name" value="RICH PROTEIN MS8, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="29452" checksum="F3840BD4BDC0CF68" modified="2011-12-14" version="1">MSASDYYNNNNNSYTHPQNQGQQYQGQPYQGQPYQGQPYQGQQYQGQQYQGQPYQQPPQYQQYPQYPPPQQQQPAPYASQQQLAPYDHDAKRPTSAQSASSHHQQQQQQQQQQYYQDPNRAGGPSAQYPGPGGEAGERGLMSTVVGGAGGAFLGNKVGNGGKLKMMLGAVAGAVAANVVSHKIKDHRQDHHQQQQQQHHGGGGLMGMIPGMHGHQQQQHGHHHQSGYDSEGSHHHGHHQHGHHHGHHHGHHHHGHHHGHHHGNGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI55</accession>
    <name>G4NI55_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mannan endo-1,4-beta-mannosidase A</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Endo-beta-1,4-mannanase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_11999</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720282.1">
        <property type="nucleotide sequence ID" value="XM_003720234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI55"/>
    <dbReference type="SMR" id="G4NI55"/>
    <dbReference type="STRING" id="242507.G4NI55"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="GeneID" id="2680312"/>
    <dbReference type="KEGG" id="mgr:MGG_11999"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11999"/>
    <dbReference type="eggNOG" id="ENOG502QS4Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031603_4_0_1"/>
    <dbReference type="InParanoid" id="G4NI55"/>
    <dbReference type="OMA" id="YHDGFSI"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046355">
        <property type="term" value="P:mannan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000076">
        <property type="entry name" value="Mannan endo-1,4-beta-mannosidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF21">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466976" description="Mannan endo-1,4-beta-mannosidase A" evidence="11">
        <location>
            <begin position="22"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="12">
        <location>
            <begin position="33"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00077212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA47915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="407" mass="45510" checksum="F62150257575F898" modified="2011-12-14" version="1">MFFAASSLLTLGLMLAEGAFAAPTIETRQAKSGFVSVEGEKFKLDGKDFYFAGTNAYYFPFSGSQTDVENGMTQAKKAGLNVVRTWGFNDKNRTTNSGGLPQYSADSNPTFQYFNGNQDSTIDVTPFDKVVNAATKTNMKLVVALTNNWADYGGMDVYTVNLGGKYHDDFYTVPKIKDAFKRYIRAMVTRYADSPAIMAWEIANEPRCGADSVRNLPRGPSCTPDTITAWIDEMSTFIKSIDSKHLVTWGGEGGFNIPSNSDGFYNGYDGGDFDKELSLPNVDFGVFHSYPDWWSKTIDWVDQWIRDHAASGRKAGKPVVHEEYGWLTNEARQANLGRTAPESRIEVLSRWQKIQVEEKMPDMFWQFGWSGFSYGKNHDDGFTIYLEDAEAQPLVRDHAAAMNALNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIC9</accession>
    <name>G4NIC9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_17827</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720356.1">
        <property type="nucleotide sequence ID" value="XM_003720308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIC9"/>
    <dbReference type="SMR" id="G4NIC9"/>
    <dbReference type="FunCoup" id="G4NIC9">
        <property type="interactions" value="445"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NIC9"/>
    <dbReference type="GeneID" id="12987301"/>
    <dbReference type="KEGG" id="mgr:MGG_17827"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17827"/>
    <dbReference type="eggNOG" id="KOG2682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_0_3_1"/>
    <dbReference type="InParanoid" id="G4NIC9"/>
    <dbReference type="OMA" id="ECKEEYP"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01408">
        <property type="entry name" value="SIRT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="20"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="298"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="338"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA47989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="460" mass="49678" checksum="E937E7F2C78D190F" modified="2011-12-14" version="1">MSLFGFNPFGLGSREPAAPQTLESRTLEAVADHIKSGKVKRITVMTGAGISTAAGIPDFRSPGTGLYSNLERLKLPEPEAVFDISFFRDRPEPFYVLAKELYPGKFQPTISHAFIALLSKKGLLQMNFTQNIDCLERQAGVPGEKVIEAHGSFATQSCIECKELFPDDEMLLHVEKEIVPRCASCNGLVKPNIVFFGEPLPRTFSEKCHLVAESDLAIIIGTSLTVYPFAGLPELVPRGSPRLLLNKVRVGQIGTRSDDVVELGSCDAGVRKLADLLGWRDELEDLWRSVVGDAEADRQIAAKDDEQGGYSDDSSDSDPDEDMRKLAEVVNRMNLGLETSAVDDSSSKPGDDGVPKATMKSPDETASSDNLKPEDPSMGDKHKMEQSNSTQVRSVESQQKKGTGASNQVEEAVSTHGSAGEAKTKNTRPDTSQQAQPPVNALAAPVQSSSGGKVEEVEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIP6</accession>
    <name>G4NIP6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cation efflux system protein czcD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_04161</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719669.1">
        <property type="nucleotide sequence ID" value="XM_003719621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIP6"/>
    <dbReference type="SMR" id="G4NIP6"/>
    <dbReference type="GeneID" id="2677316"/>
    <dbReference type="KEGG" id="mgr:MGG_04161"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04161"/>
    <dbReference type="eggNOG" id="KOG1483">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013430_4_0_1"/>
    <dbReference type="InParanoid" id="G4NIP6"/>
    <dbReference type="OMA" id="CFTIFVD"/>
    <dbReference type="OrthoDB" id="5234656at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF5">
        <property type="entry name" value="DIFFUSION FACILITATOR FAMILY METAL ION TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="9">
        <location>
            <begin position="11"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="10">
        <location>
            <begin position="225"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="353" mass="38948" checksum="C390869DF2E4FBB9" modified="2011-12-14" version="1">MVFHISRKSRIIIAISISALFFIAELYVAFRTRSLALMADAFHYINDVVSFVIGLVAIMLSERKETPPEMLSFGWQRATILGSFFNGVFLLALGLSIFLQSIERFVSLELFADDGDVQNIMIIPVDILTVTHTASNMNMQTNQSRTIHGTLWMHMLNMLNIGTTSKLPWPRVMPMILTSSEARFYADPAISTFIAIMIFVTAVPLVRKSGEILLQSVPVGLSPSDVTHDLEKIPGVDSVHHLHIWRLDQTKTVASVHVVVQDEAISDFMTKARTVTECLHAYGIHTAIIQPEVAFHQGPALPAVISDEDQASIGISTLIPASSSSSSRTNTGQRGTRCQMPCSSLCEDLRCCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJX5</accession>
    <name>G4NJX5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_18031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721247.1">
        <property type="nucleotide sequence ID" value="XM_003721199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJX5"/>
    <dbReference type="GeneID" id="12985796"/>
    <dbReference type="KEGG" id="mgr:MGG_18031"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18031"/>
    <dbReference type="HOGENOM" id="CLU_1731863_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJX5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="151" mass="17333" checksum="B86073557E55C78E" modified="2011-12-14" version="1">MRAHSPQERWWVMVRRERHSRIIASWQKSIGLVSPSCYQSVSPRRDSPWVGLASLDGVSKTLIGPLKARVQRPQSREYHKHVSCSKDPHYKALLKIIMSFVLSVNINWDKSLVAIQNVQMPRPPRPKYPEHGAGTRYLRSTPAADRARARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKF0</accession>
    <name>G4NKF0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721329.1">
        <property type="nucleotide sequence ID" value="XM_003721281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKF0"/>
    <dbReference type="GeneID" id="2680135"/>
    <dbReference type="KEGG" id="mgr:MGG_09012"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09012"/>
    <dbReference type="HOGENOM" id="CLU_1712898_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKF0"/>
    <dbReference type="OMA" id="YLEPIMI"/>
    <dbReference type="OrthoDB" id="2937326at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056121">
        <property type="entry name" value="DUF7704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37019:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24803">
        <property type="entry name" value="DUF7704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7704" evidence="2">
        <location>
            <begin position="3"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="158" mass="16992" checksum="AF35CBCD56147503" modified="2011-12-14" version="1">MASFMAPFPRIYFCYVEPLLLCYGGLSHIINPGHYTAALFGDLASSDVDYLPTEKLAGMNLGFMMLLVGALVAVVMFTCENRRTAYLVALALMLSDIAHWGAVAAVLGPAGPAAIEVANWTTEMKGHMFGPIVTFSIKLAYLLGWLGDDLPTAKGKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKZ1</accession>
    <name>G4NKZ1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721426.1">
        <property type="nucleotide sequence ID" value="XM_003721378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKZ1"/>
    <dbReference type="GeneID" id="2680570"/>
    <dbReference type="KEGG" id="mgr:MGG_09663"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09663"/>
    <dbReference type="HOGENOM" id="CLU_2292258_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKZ1"/>
    <dbReference type="OrthoDB" id="4581920at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="101" mass="11416" checksum="FF53DDEF9D78A771" modified="2011-12-14" version="1">MDSVKKSNQQRAPGSLQRITQYTQSNQRDVERNIQASAICPRRAQLEQVCRLWDDENGGIRTEHASVGRHCQTLYSGMEPKDNGKDNHASVKASTCRRQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G5EGV4</accession>
    <name>G5EGV4_PYRO7</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">MGG_17992</name>
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    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="EHA46323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003721018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EGV4"/>
    <dbReference type="GeneID" id="12984881"/>
    <dbReference type="KEGG" id="mgr:MGG_17992"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17992"/>
    <dbReference type="HOGENOM" id="CLU_2210565_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ71031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="107" mass="12704" checksum="040EC08595101F78" modified="2011-12-14" version="1">MHHAVASPTPPLMETQKELSLLNYLVRGMITSHSHKLYNCLPWLGNQVLLRRSKYKFVGCDVGGAQAAYWVEVRKDYKQATGRWRFSRMCKSHFRRWLEKSGQHRWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH09</accession>
    <name>G5EH09_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">2-methylcitrate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGCH7_ch7g591</name>
        <name evidence="7" type="ORF">MGG_02836</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15</strain>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">70-15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpD family.</text>
    </comment>
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        <property type="protein sequence ID" value="EAQ71184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="EHA46159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720902.1">
        <property type="nucleotide sequence ID" value="XM_003720854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH09"/>
    <dbReference type="SMR" id="G5EH09"/>
    <dbReference type="FunCoup" id="G5EH09">
        <property type="interactions" value="33"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EH09"/>
    <dbReference type="GeneID" id="2682389"/>
    <dbReference type="KEGG" id="mgr:MGG_02836"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02836"/>
    <dbReference type="eggNOG" id="ENOG502QPZI">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_021803_1_0_1"/>
    <dbReference type="OMA" id="DHSVMYI"/>
    <dbReference type="OrthoDB" id="10055203at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047547">
        <property type="term" value="F:2-methylcitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.120:FF:000001">
        <property type="entry name" value="2-methylcitrate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4100.10">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="2Me_IsoCit_deHydtase_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036148">
        <property type="entry name" value="MmgE/PrpD_sf"/>
    </dbReference>
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        <property type="entry name" value="MmgE/PrpD_sf_1"/>
    </dbReference>
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    <dbReference type="InterPro" id="IPR005656">
        <property type="entry name" value="MmgE_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045337">
        <property type="entry name" value="MmgE_PrpD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045336">
        <property type="entry name" value="MmgE_PrpD_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006943">
        <property type="entry name" value="PRK09425.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02330">
        <property type="entry name" value="prpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943:SF16">
        <property type="entry name" value="2-METHYLCITRATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19305">
        <property type="entry name" value="MmgE_PrpD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03972">
        <property type="entry name" value="MmgE_PrpD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103378">
        <property type="entry name" value="2-methylcitrate dehydratase PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MmgE/PrpD N-terminal" evidence="4">
        <location>
            <begin position="84"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="MmgE/PrpD C-terminal" evidence="5">
        <location>
            <begin position="364"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03972"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF19305"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EAQ71184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA46159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="570" mass="62601" checksum="2012794A05447121" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH36</accession>
    <name>G5EH36_PYRO7</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_18019</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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            <taxon>Magnaporthales</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH36"/>
    <dbReference type="GeneID" id="12985778"/>
    <dbReference type="KEGG" id="mgr:MGG_18019"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18019"/>
    <dbReference type="HOGENOM" id="CLU_2264279_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="22"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="103" mass="10742" checksum="2D63ABB6B701483A" modified="2011-12-14" version="1">MQFKSALALSIAALQAVPALAMEDGCSASILKYDANGGQETYYGSALPANGSIAFQPTEFSTEVVISVDANCNPTNTDDVKKSVPKGWGLHVYKKVTAIAGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHH2</accession>
    <name>G5EHH2_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g511</name>
        <name evidence="3" type="ORF">MGG_17971</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="EHA46245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720988.1">
        <property type="nucleotide sequence ID" value="XM_003720940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHH2"/>
    <dbReference type="GeneID" id="12984856"/>
    <dbReference type="KEGG" id="mgr:MGG_17971"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17971"/>
    <dbReference type="HOGENOM" id="CLU_3106887_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="51" mass="5446" checksum="6D031592D7EF1ABD" modified="2011-12-14" version="1">MGLSTTCQIEICISALYSVDLKAMAGGLSNKGPDEAKSRQANSRRPLPHTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHK9</accession>
    <name>G5EHK9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g693</name>
        <name evidence="2" type="ORF">MGG_02929</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720787.1">
        <property type="nucleotide sequence ID" value="XM_003720739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHK9"/>
    <dbReference type="SMR" id="G5EHK9"/>
    <dbReference type="GeneID" id="2682482"/>
    <dbReference type="KEGG" id="mgr:MGG_02929"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02929"/>
    <dbReference type="eggNOG" id="ENOG502SKQE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028906_1_2_1"/>
    <dbReference type="OMA" id="WKYIDER"/>
    <dbReference type="OrthoDB" id="5412996at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ71286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="262" mass="30739" checksum="84394254D987618C" modified="2011-12-14" version="1">MQFATPLVQNNYMVSSENDCKAKYVAWRLFRRLAKQGRLSLFGFAEDNWSAGRRDAAAKLPMPGRCRPFRLWCDDFRPANAIFVLDPPWWLPLEVPEMRDDGIDHWASVYDRRMQNGLAAMEDAEKEADYTSMQESNRKITSTGPDQTPPLLPLPYMRESWATGQFWLNYAARKSWAFDTIYWKYIDERFFGNRDENIPKDELWKTRVHLLNQEERGAIEIMVQIKIEESKERVLVERDAASAEQRFSHFLFEGSLSSVHNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHL3</accession>
    <name>G5EHL3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGCH7_ch7g813</name>
        <name evidence="19" type="ORF">MGG_03026</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15</strain>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">70-15</strain>
        </source>
    </reference>
    <reference evidence="19" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720661.1">
        <property type="nucleotide sequence ID" value="XM_003720613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHL3"/>
    <dbReference type="SMR" id="G5EHL3"/>
    <dbReference type="FunCoup" id="G5EHL3">
        <property type="interactions" value="305"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EHL3"/>
    <dbReference type="GeneID" id="2682579"/>
    <dbReference type="KEGG" id="mgr:MGG_03026"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03026"/>
    <dbReference type="eggNOG" id="KOG0591">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_63_23_1"/>
    <dbReference type="OMA" id="AYFERDH"/>
    <dbReference type="OrthoDB" id="10250725at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0075016">
        <property type="term" value="P:appressorium formation"/>
        <property type="evidence" value="ECO:0000315"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0000315"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="CDD" id="cd08217">
        <property type="entry name" value="STKc_Nek2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000697">
        <property type="entry name" value="G2-specific protein kinase nimA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000525">
        <property type="entry name" value="Serine/threonine-protein kinase KIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF13">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="7"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="401"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="510"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="516"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EAQ71406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA45918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="591" mass="67724" checksum="84546CC0F3C8A28B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI63</accession>
    <name>G5EI63_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g87</name>
        <name evidence="2" type="ORF">MGG_18072</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721420.1">
        <property type="nucleotide sequence ID" value="XM_003721372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI63"/>
    <dbReference type="GeneID" id="12986024"/>
    <dbReference type="KEGG" id="mgr:MGG_18072"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18072"/>
    <dbReference type="HOGENOM" id="CLU_2386608_0_0_1"/>
    <dbReference type="OMA" id="YDWQEKP"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ70680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="94" mass="10700" checksum="F50063DF1A852A08" modified="2011-12-14" version="1">MARGLGVANPVTGFKVCEKRMVAMVQLKLALGRPGTSKWYVADLQENLPLEIWWDLRLRAATAQSSQRHLEGRPAYTGYDWQEKPLLDLLRSTM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-11-16" modified="2026-01-28" version="130" xmlns="https://uniprot.org/uniprot">
    <accession>P58371</accession>
    <accession>A4QR64</accession>
    <accession>G4N6T0</accession>
    <name>SPM1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Subtilisin-like proteinase Spm1</fullName>
            <ecNumber>3.4.21.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Serine protease of Magnaporthe 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">SPM1</name>
        <name type="ORF">MGG_03670</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2002" name="Biosci. Biotechnol. Biochem." volume="66" first="663" last="666">
            <title>Identification of a putative vacuolar serine protease gene in the rice blast fungus, Magnaporthe grisea.</title>
            <authorList>
                <person name="Fukiya S."/>
                <person name="Kuge T."/>
                <person name="Tanishima T."/>
                <person name="Sone T."/>
                <person name="Kamakura T."/>
                <person name="Yamaguchi I."/>
                <person name="Tomita F."/>
            </authorList>
            <dbReference type="PubMed" id="12005067"/>
            <dbReference type="DOI" id="10.1271/bbb.66.663"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>Hoku1</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-"/>
    <dbReference type="EMBL" id="AB070268">
        <property type="protein sequence ID" value="BAB63284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JC7826">
        <property type="entry name" value="JC7826"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716216.1">
        <property type="nucleotide sequence ID" value="XM_003716168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P58371"/>
    <dbReference type="SMR" id="P58371"/>
    <dbReference type="FunCoup" id="P58371">
        <property type="interactions" value="312"/>
    </dbReference>
    <dbReference type="MEROPS" id="S08.052"/>
    <dbReference type="GlyCosmos" id="P58371">
        <property type="glycosylation" value="2 sites, No reported glycans"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_03670T0">
        <property type="protein sequence ID" value="MGG_03670T0"/>
        <property type="gene ID" value="MGG_03670"/>
    </dbReference>
    <dbReference type="GeneID" id="2676592"/>
    <dbReference type="KEGG" id="mgr:MGG_03670"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03670"/>
    <dbReference type="eggNOG" id="KOG1153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011263_1_4_1"/>
    <dbReference type="InParanoid" id="P58371"/>
    <dbReference type="OMA" id="RHPDVDY"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="PHI-base" id="PHI:2117"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019863">
        <property type="term" value="F:IgE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000425">
        <property type="term" value="P:pexophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.80:FF:000006">
        <property type="entry name" value="Autophagic serine protease Alp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0720">Serine protease</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0926">Vacuole</keyword>
    <keyword id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="propeptide" id="PRO_0000027165" evidence="1">
        <location>
            <begin position="16"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000027166" description="Subtilisin-like proteinase Spm1">
        <location>
            <begin position="148"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="2">
        <location>
            <begin position="44"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8" evidence="3">
        <location>
            <begin position="156"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="536" mass="57170" checksum="85D112486CD8545B" modified="2001-11-16" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-08-30" modified="2026-01-28" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>Q525S7</accession>
    <accession>A4R1C1</accession>
    <accession>G4MNV9</accession>
    <name>SEY1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein SEY1</fullName>
            <ecNumber evidence="1">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SEY1</name>
        <name type="ORF">MGG_06979</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Enriched in the cortical ER. Concentrated in punctae along the ER tubules.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="1"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709728.1">
        <property type="nucleotide sequence ID" value="XM_003709680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q525S7"/>
    <dbReference type="SMR" id="Q525S7"/>
    <dbReference type="FunCoup" id="Q525S7">
        <property type="interactions" value="68"/>
    </dbReference>
    <dbReference type="STRING" id="242507.Q525S7"/>
    <dbReference type="EnsemblFungi" id="MGG_06979T0">
        <property type="protein sequence ID" value="MGG_06979T0"/>
        <property type="gene ID" value="MGG_06979"/>
    </dbReference>
    <dbReference type="GeneID" id="2685152"/>
    <dbReference type="KEGG" id="mgr:MGG_06979"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06979"/>
    <dbReference type="eggNOG" id="KOG2203">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011270_0_0_1"/>
    <dbReference type="InParanoid" id="Q525S7"/>
    <dbReference type="OMA" id="PIIKMTE"/>
    <dbReference type="OrthoDB" id="1597724at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048309">
        <property type="term" value="P:endoplasmic reticulum inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016320">
        <property type="term" value="P:endoplasmic reticulum membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01851">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000727">
        <property type="entry name" value="Protein SEY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03109">
        <property type="entry name" value="Sey1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030386">
        <property type="entry name" value="G_GB1_RHD3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008803">
        <property type="entry name" value="RHD3/Sey1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046758">
        <property type="entry name" value="Sey1/RHD3-like_3HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923:SF2">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05879">
        <property type="entry name" value="RHD3_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20428">
        <property type="entry name" value="Sey1_3HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51715">
        <property type="entry name" value="G_GB1_RHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000155135" description="Protein SEY1">
        <location>
            <begin position="1"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="734"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="1">
        <location>
            <begin position="755"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="758"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="779"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="GB1/RHD3-type G" evidence="2">
        <location>
            <begin position="47"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="815"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="829"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="57"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="848" mass="95441" checksum="93E390C2455C2F15" modified="2005-06-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4R2</accession>
    <name>A0A151V4R2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Starter acyltransferase (SAT) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165184">
        <property type="protein sequence ID" value="KYQ30565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846069.1">
        <property type="nucleotide sequence ID" value="XM_016990558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4R2"/>
    <dbReference type="SMR" id="A0A151V4R2"/>
    <dbReference type="GeneID" id="27922182"/>
    <dbReference type="KEGG" id="mgr:MGG_15487"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15487"/>
    <dbReference type="InParanoid" id="A0A151V4R2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Starter acyltransferase (SAT)" evidence="1">
        <location>
            <begin position="9"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KYQ30565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="105" mass="11338" checksum="B7B81E8D6171FC05" modified="2016-06-08" version="1">MVIKRHSILLFGDYTDPWIDALDGITLQAASSPWLQKFLDDVASIVLAETRQMDGPLRQSLTVGSTGVMFSSLADLADAHRGKTDDVGFVDAVMVYIVRAAALLG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-09-11" modified="2026-01-28" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4R596</accession>
    <accession>G4NIP7</accession>
    <name>IML1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Vacuolar membrane-associated protein IML1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">IML1</name>
        <name type="ORF">MGG_04160</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IML1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719670.1">
        <property type="nucleotide sequence ID" value="XM_003719622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R596"/>
    <dbReference type="FunCoup" id="A4R596">
        <property type="interactions" value="624"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4R596"/>
    <dbReference type="EnsemblFungi" id="MGG_04160T0">
        <property type="protein sequence ID" value="MGG_04160T0"/>
        <property type="gene ID" value="MGG_04160"/>
    </dbReference>
    <dbReference type="GeneID" id="2677315"/>
    <dbReference type="KEGG" id="mgr:MGG_04160"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04160"/>
    <dbReference type="eggNOG" id="KOG3572">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000935_0_0_1"/>
    <dbReference type="InParanoid" id="A4R596"/>
    <dbReference type="OMA" id="SWMNATP"/>
    <dbReference type="OrthoDB" id="39497at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="CDD" id="cd04449">
        <property type="entry name" value="DEP_DEPDC5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045838">
        <property type="entry name" value="DEPDC5_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027244">
        <property type="entry name" value="IML1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048255">
        <property type="entry name" value="IML1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13179">
        <property type="entry name" value="DEP DOMAIN CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13179:SF8">
        <property type="entry name" value="GATOR COMPLEX PROTEIN DEPDC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19418">
        <property type="entry name" value="DEPDC5_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12257">
        <property type="entry name" value="IML1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0926">Vacuole</keyword>
    <feature type="chain" id="PRO_0000301774" description="Vacuolar membrane-associated protein IML1">
        <location>
            <begin position="1"/>
            <end position="1874"/>
        </location>
    </feature>
    <feature type="domain" description="DEP" evidence="2">
        <location>
            <begin position="1304"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="106"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1363"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1671"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1671"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1691"/>
            <end position="1702"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="1874" mass="209930" checksum="F97316BC89E20BE6" modified="2012-01-25" version="2"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-04-29" modified="2026-01-28" version="109" xmlns="https://uniprot.org/uniprot">
    <accession>A4RLF4</accession>
    <accession>G4MWZ8</accession>
    <name>DUS3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="1">1.3.1.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>mRNA-dihydrouridine synthase DUS3</fullName>
            <ecNumber evidence="3">1.3.1.-</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName>tRNA-dihydrouridine synthase 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">DUS3</name>
        <name type="ORF">MGG_01205</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs (By similarity). Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="1">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="1">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="3">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="3">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Dus family. Dus3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="1"/>
    <dbReference type="EC" id="1.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714097.1">
        <property type="nucleotide sequence ID" value="XM_003714049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RLF4"/>
    <dbReference type="SMR" id="A4RLF4"/>
    <dbReference type="FunCoup" id="A4RLF4">
        <property type="interactions" value="884"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RLF4"/>
    <dbReference type="EnsemblFungi" id="MGG_01205T0">
        <property type="protein sequence ID" value="MGG_01205T0"/>
        <property type="gene ID" value="MGG_01205"/>
    </dbReference>
    <dbReference type="GeneID" id="2679761"/>
    <dbReference type="KEGG" id="mgr:MGG_01205"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01205"/>
    <dbReference type="eggNOG" id="KOG2333">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_7_0_1"/>
    <dbReference type="InParanoid" id="A4RLF4"/>
    <dbReference type="OMA" id="WSYIAEC"/>
    <dbReference type="OrthoDB" id="259935at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106414">
        <property type="term" value="F:mRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000145">
        <property type="entry name" value="tRNA-dihydrouridine(47) synthase [NAD(P)(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25585">
        <property type="entry name" value="zf-CCCH_DUS3L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0288">FMN</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_0000330242" description="tRNA-dihydrouridine(47) synthase [NAD(P)(+)]">
        <location>
            <begin position="1"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type 1" evidence="4">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type 2" evidence="4">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="330"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="523"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="580"/>
            <end position="582"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="604"/>
            <end position="605"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q06053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="Q5SMC7"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="3">
        <source>
            <dbReference type="UniProtKB" id="Q9UTH9"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="6"/>
    <sequence length="739" mass="82693" checksum="7875C7860FE3B32A" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKD6</accession>
    <name>G4MKD6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">E3 ubiquitin-protein ligase listerin</fullName>
            <ecNumber evidence="5 16">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">RING-type E3 ubiquitin transferase listerin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_10526</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Mediates ubiquitination of proteins derived from mRNAs lacking stop codons (non-stop proteins) and other translation arrest products induced by poly-lysine sequences and tandem rare codons. Ubiquitination leads to CDC48 recruitment for extraction and degradation of the incomplete translation product. May indirectly play a role in chromatin function and transcription.</text>
    </comment>
    <comment type="function">
        <text evidence="16">E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the ribosome quality control complex (RQC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the LTN1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5 16"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710137.1">
        <property type="nucleotide sequence ID" value="XM_003710089.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MKD6"/>
    <dbReference type="FunCoup" id="G4MKD6">
        <property type="interactions" value="583"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKD6"/>
    <dbReference type="GeneID" id="2682161"/>
    <dbReference type="KEGG" id="mgr:MGG_10526"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10526"/>
    <dbReference type="eggNOG" id="KOG0803">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000471_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKD6"/>
    <dbReference type="OMA" id="IYGSHWE"/>
    <dbReference type="OrthoDB" id="6108at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16491">
        <property type="entry name" value="RING-CH-C4HC3_LTN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000038">
        <property type="entry name" value="E3 ubiquitin-protein ligase listerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039795">
        <property type="entry name" value="LTN1/Rkr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054477">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054476">
        <property type="entry name" value="Ltn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054478">
        <property type="entry name" value="LTN1_UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039804">
        <property type="entry name" value="RING-CH-C4HC3_LTN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057030">
        <property type="entry name" value="TPR_Rkr-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE LISTERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12389">
        <property type="entry name" value="ZINC FINGER PROTEIN 294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22958">
        <property type="entry name" value="Ltn1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22999">
        <property type="entry name" value="LTN1_E3_ligase_6th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23280">
        <property type="entry name" value="TPR_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23009">
        <property type="entry name" value="UBC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01197">
        <property type="entry name" value="FANCL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13 16" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 15 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="1570"/>
            <end position="1616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA57525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1634" mass="180080" checksum="6DEA4131E7508CF9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKW0</accession>
    <name>G4MKW0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710207.1">
        <property type="nucleotide sequence ID" value="XM_003710159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKW0"/>
    <dbReference type="GeneID" id="12985374"/>
    <dbReference type="KEGG" id="mgr:MGG_16339"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16339"/>
    <dbReference type="HOGENOM" id="CLU_2441272_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKW0"/>
    <dbReference type="OrthoDB" id="10368392at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465071" evidence="1">
        <location>
            <begin position="20"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="90" mass="9350" checksum="85624AF3708D0C2E" modified="2011-12-14" version="1">MRFSIAVIATASLASSAAAAPVTNLFDALLLPKAGRGCQPWLDLNSGSYACRDREMFNCDGSKTWVLLSTCGEGTKCEKSSSGGVNCVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMP3</accession>
    <name>G4MMP3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Xenobiotic compound monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05555</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710427.1">
        <property type="nucleotide sequence ID" value="XM_003710379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMP3"/>
    <dbReference type="SMR" id="G4MMP3"/>
    <dbReference type="GeneID" id="2675796"/>
    <dbReference type="KEGG" id="mgr:MGG_05555"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05555"/>
    <dbReference type="eggNOG" id="ENOG502QSR6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022256_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMP3"/>
    <dbReference type="OMA" id="SWRGDEI"/>
    <dbReference type="OrthoDB" id="5561043at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="entry name" value="Luciferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051260">
        <property type="entry name" value="Diverse_substr_monoxygenases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011">
        <property type="entry name" value="ALKANESULFONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30011:SF16">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="Bacterial luciferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Luciferase-like" evidence="6">
        <location>
            <begin position="37"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA57815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="481" mass="53769" checksum="529D65F3378BC6E8" modified="2011-12-14" version="1">MSLHNGAATRKKQLVINAFVEMCSGHQSPGLWRHPADESWRFNDVDHWVRLAKLLEEAKFHGIFIADVLGGYDVYKNSLDPAIISGAQWPVNEPLSVVPAMAAATKSIGFGVTASTTYEQPFHLARRLSTVDHLTKGRVGWNIVTGYLDSAARNLGKTEQPQHDDRYAQAEEYMKVMYKLFNSSWRDDAVQLNREKGIYTDPSLVRQINHEGKFFTVPGPHIVQPSPQRTPLLLQAGTSRAGKEFAAQHAEAIFVSAHSPAVPAASIAEIRRLARDKYGRDPDSIKVLALVTVILGRTEDEAREKLRDYRQYASLEGALALFCGWTGINLDQYGDEEELRQVESNAVRSTVEGYAKFSPVNSKWTKHTVAEHISIGGNGPLLVGTAAQVADGLETWIREADVDGFNFAYAVFPQSFKDIIELLLPELRSRGLFWDDYAVPGGTYRENFYGRKGQTFPPDEHVTSKYRWRQGVDATEHVIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN15</accession>
    <name>G4MN15_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Wings apart-like protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_11796</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WAPL family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709649.1">
        <property type="nucleotide sequence ID" value="XM_003709601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN15"/>
    <dbReference type="STRING" id="242507.G4MN15"/>
    <dbReference type="GeneID" id="5049584"/>
    <dbReference type="KEGG" id="mgr:MGG_11796"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11796"/>
    <dbReference type="eggNOG" id="ENOG502RZXD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011973_1_0_1"/>
    <dbReference type="InParanoid" id="G4MN15"/>
    <dbReference type="OMA" id="NNKPKAC"/>
    <dbReference type="OrthoDB" id="78088at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039874">
        <property type="entry name" value="WAPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022771">
        <property type="entry name" value="WAPL_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100:SF13">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07814">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wings apart-like protein C-terminal" evidence="3">
        <location>
            <begin position="437"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="276"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="897" mass="97684" checksum="0480A5B4A5F0E451" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN52</accession>
    <name>G4MN52_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710478.1">
        <property type="nucleotide sequence ID" value="XM_003710430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN52"/>
    <dbReference type="SMR" id="G4MN52"/>
    <dbReference type="STRING" id="242507.G4MN52"/>
    <dbReference type="GeneID" id="2676124"/>
    <dbReference type="KEGG" id="mgr:MGG_05597"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05597"/>
    <dbReference type="eggNOG" id="ENOG502SAUS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086044_0_1_1"/>
    <dbReference type="InParanoid" id="G4MN52"/>
    <dbReference type="OMA" id="YQRKGWG"/>
    <dbReference type="OrthoDB" id="64477at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050276">
        <property type="entry name" value="MshD_Acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43617">
        <property type="entry name" value="L-AMINO ACID N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43617:SF20">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE RIMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="236" mass="26473" checksum="32C5C8B78DF59C2A" modified="2011-12-14" version="1">MAFIRPYQPTDFEATAFICRATLPPSLAKSPAGVKLSPYLWTHQYTELSPSHCFVLDDGSGRCVGYVIGTPDVFAFAAAYHGYVAKHLATADMTPRQMETREAWTTADGEVNEQALLQLARSPRWLLLEGVEGKEEMVQRYRGTMHIDMLEDFQGKGWGRKLIGEFMESVRRRQGERVPVVLEDGTAQEMMLDSGKGVHIGISGENTKVVKFYEKVGFRVQEGGEREGGVWMVYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNA7</accession>
    <name>G4MNA7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708842.1">
        <property type="nucleotide sequence ID" value="XM_003708794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNA7"/>
    <dbReference type="GeneID" id="12985696"/>
    <dbReference type="KEGG" id="mgr:MGG_16030"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16030"/>
    <dbReference type="HOGENOM" id="CLU_2942214_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNA7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="60" mass="6292" checksum="F6D6C4627DC3EDCD" modified="2011-12-14" version="1">MLQIAGLPCGGIGTVGLRLYGYTKIKVEQLWTRGSGSPGGDGGRRLEIVAKGDVRLFASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPL5</accession>
    <name>G4MPL5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708976.1">
        <property type="nucleotide sequence ID" value="XM_003708928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPL5"/>
    <dbReference type="SMR" id="G4MPL5"/>
    <dbReference type="STRING" id="242507.G4MPL5"/>
    <dbReference type="GeneID" id="2681282"/>
    <dbReference type="KEGG" id="mgr:MGG_02212"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02212"/>
    <dbReference type="eggNOG" id="ENOG502T6EW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134596_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPL5"/>
    <dbReference type="OMA" id="EVVAYYT"/>
    <dbReference type="OrthoDB" id="5212903at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021054">
        <property type="entry name" value="Cell_wall_mannoprotein_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123">
        <property type="entry name" value="CELL WALL SERINE-THREONINE-RICH GALACTOMANNOPROTEIN MP1 (AFU_ORTHOLOGUE AFUA_4G03240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38123:SF1">
        <property type="entry name" value="HYDROPHOBIC SURFACE BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12296">
        <property type="entry name" value="HsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465342" description="Cell wall protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="16596" checksum="FFBE76EA0AA417F0" modified="2011-12-14" version="1">MRLSTFLVPVASILGLACAQIGAINTALADIRNDVDAVKNAFNAGTPAGITSSFTELDDSISAATTVVNNSPAIGLLDALSLANTIGSLQTSIDQAFTVLKAKRTAVDALGLTGAVRTSLVGQRSAVDMLGGKVISKVPGIVKGTARSFMAQLDASYAAAIAASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPL8</accession>
    <name>G4MPL8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_16063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708979.1">
        <property type="nucleotide sequence ID" value="XM_003708931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPL8"/>
    <dbReference type="GeneID" id="12984296"/>
    <dbReference type="KEGG" id="mgr:MGG_16063"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16063"/>
    <dbReference type="eggNOG" id="ENOG502SZCW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019059_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPL8"/>
    <dbReference type="OMA" id="MPSNQYN"/>
    <dbReference type="OrthoDB" id="5361322at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032567">
        <property type="entry name" value="RTL1-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503">
        <property type="entry name" value="LDOC1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503:SF22">
        <property type="entry name" value="TRANSPOSON TY3-I GAG POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="341"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="407"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="527"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="358"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="560" mass="64145" checksum="D6CD2A94E01276B1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPN6</accession>
    <name>G4MPN6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydrodipicolinate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708997.1">
        <property type="nucleotide sequence ID" value="XM_003708949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPN6"/>
    <dbReference type="SMR" id="G4MPN6"/>
    <dbReference type="STRING" id="242507.G4MPN6"/>
    <dbReference type="GeneID" id="2681301"/>
    <dbReference type="KEGG" id="mgr:MGG_02231"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02231"/>
    <dbReference type="eggNOG" id="ENOG502RBA9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_4_1_1"/>
    <dbReference type="InParanoid" id="G4MPN6"/>
    <dbReference type="OMA" id="PHHWLRF"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF38">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHETASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G00110)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="311" mass="33984" checksum="8E893952E030F5B0" modified="2011-12-14" version="1">MAPINIDLRGLTPAPVTPFTKDGAVDYPAIQRLGSWLGSISGVKGLVVLGHAGEGTFLTPEEQCDVIRAFVKSVDNKIPIIAGITGEGTEVAAFEAKRAVEAGASAGLLYPSHGWLRFGYQPGAPQDRYKVVYERSGLPLILFQYPDVTKATYSLQTMLDIAAQPGVFAMKNGVRNMRRWDTEIPVIRRERPDLQILSCHDEYLLHTAFDVDGFLVGYGCIAPEPLLEMIDAGKRKDYAKAREVHDRLLPVTKNVYHRGSHMEGTVALKHALVARGILEHATVRSPLLPLPDGAETEIHDAIKISALSRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPY9</accession>
    <name>G4MPY9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Stress responsive A/B barrel domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710689.1">
        <property type="nucleotide sequence ID" value="XM_003710641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPY9"/>
    <dbReference type="SMR" id="G4MPY9"/>
    <dbReference type="GeneID" id="2676075"/>
    <dbReference type="KEGG" id="mgr:MGG_05763"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05763"/>
    <dbReference type="eggNOG" id="ENOG502S73V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080664_2_1_1"/>
    <dbReference type="InParanoid" id="G4MPY9"/>
    <dbReference type="OMA" id="QMAGRNI"/>
    <dbReference type="OrthoDB" id="1601230at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044662">
        <property type="entry name" value="HS1/DABB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178:SF10">
        <property type="entry name" value="STRESS-RESPONSE A_B BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="2">
        <location>
            <begin position="3"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="110" mass="12394" checksum="8F600310F066428D" modified="2011-12-14" version="1">MTQVHTVLFTFKSSASDDQVKDACKQFITLKDKCIHPTSQAPYILSLKAGRDNSEEDCQEGLTHAFVVEFASAEDRDYYTHKDPAHQDLIRAMDPLIERAVAVDFLDGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQR1</accession>
    <name>G4MQR1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_11728</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I LYR family. SDHAF1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709960.1">
        <property type="nucleotide sequence ID" value="XM_003709912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQR1"/>
    <dbReference type="SMR" id="G4MQR1"/>
    <dbReference type="FunCoup" id="G4MQR1">
        <property type="interactions" value="80"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MQR1"/>
    <dbReference type="GeneID" id="5049520"/>
    <dbReference type="KEGG" id="mgr:MGG_11728"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11728"/>
    <dbReference type="eggNOG" id="KOG4620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_154777_1_1_1"/>
    <dbReference type="InParanoid" id="G4MQR1"/>
    <dbReference type="OMA" id="VEMYSSP"/>
    <dbReference type="OrthoDB" id="273010at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="5">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA57348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="78" mass="9397" checksum="6CBDDE33DE4357CB" modified="2011-12-14" version="1">MRLSGLQKEVLSLYRSTLREIRKKPETSRQHFRDFARAEFDRNLVIDKRDFAAVEYLLRKGRRQLETYSAPGIKDIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR06</accession>
    <name>G4MR06_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_02378</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709153.1">
        <property type="nucleotide sequence ID" value="XM_003709105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR06"/>
    <dbReference type="SMR" id="G4MR06"/>
    <dbReference type="STRING" id="242507.G4MR06"/>
    <dbReference type="GeneID" id="2681475"/>
    <dbReference type="KEGG" id="mgr:MGG_02378"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02378"/>
    <dbReference type="eggNOG" id="KOG1383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019582_2_2_1"/>
    <dbReference type="InParanoid" id="G4MR06"/>
    <dbReference type="OMA" id="ECRDKNM"/>
    <dbReference type="OrthoDB" id="5152799at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.160:FF:000004">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.50:FF:000001">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF6">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="485"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA56541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="517" mass="58105" checksum="AD629BBD28201B89" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR34</accession>
    <name>G4MR34_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cleavage stimulation factor 64-kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_09885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709978.1">
        <property type="nucleotide sequence ID" value="XM_003709930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR34"/>
    <dbReference type="FunCoup" id="G4MR34">
        <property type="interactions" value="100"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MR34"/>
    <dbReference type="GeneID" id="2680929"/>
    <dbReference type="KEGG" id="mgr:MGG_09885"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09885"/>
    <dbReference type="eggNOG" id="KOG0108">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028601_0_1_1"/>
    <dbReference type="InParanoid" id="G4MR34"/>
    <dbReference type="OMA" id="CEPEDAP"/>
    <dbReference type="OrthoDB" id="272703at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12398">
        <property type="entry name" value="RRM_CSTF2_RNA15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.70">
        <property type="entry name" value="Transcription termination and cleavage factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026896">
        <property type="entry name" value="CSTF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038192">
        <property type="entry name" value="CSTF_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14304">
        <property type="entry name" value="CSTF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="8"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA57366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="305" mass="31883" checksum="B627C95B6EF4C4DA" modified="2011-12-14" version="1">MSSKPPSRVVFVGNIPYGLSEEQITDIFSRAGKVLNFRLVYDRETGKPKGFGFAEYPDNDSAASAVRNLNDTEIMGRKLRVDFSNEKPSTNDPDDGPPGGANGSGAPSYQQQQEVPSLPPLPPGKDIPAGVSATDAISRTLRTLPPAQLLDILQQMKTMSGADPARATELLTQAPQLSYAIFQALLLMDLVSPDAIHSVVDPGAAVPPPAAAPAHAPAPYGAPPAAAAVYQQHPVANTPPVPMPYAPPAAPTAATPTPAPAAAPQDTDALMQQVLALPQATIDQLPEAERAQIMALRASLMGQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR38</accession>
    <name>G4MR38_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tho complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09889</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709982.1">
        <property type="nucleotide sequence ID" value="XM_003709934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR38"/>
    <dbReference type="SMR" id="G4MR38"/>
    <dbReference type="STRING" id="242507.G4MR38"/>
    <dbReference type="GeneID" id="2680933"/>
    <dbReference type="KEGG" id="mgr:MGG_09889"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09889"/>
    <dbReference type="eggNOG" id="ENOG502S942">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049078_0_0_1"/>
    <dbReference type="InParanoid" id="G4MR38"/>
    <dbReference type="OMA" id="QFLHNAN"/>
    <dbReference type="OrthoDB" id="205166at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008501">
        <property type="entry name" value="THOC7/Mft1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05615">
        <property type="entry name" value="THOC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="39"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="224"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="315"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="42096" checksum="40632D0E23718A89" modified="2011-12-14" version="1">MAHFQLLDPREEEELHKSRLLNIEEKPFKRITKRMQTLHAAARWGKQPTPANATTIASPTAADTNQNGTTTSSRPPTSGGAPPPASDELQMLRQELTLDFAAFDSTVARLQFLMRANEEERRRYGEDREQILAECEDVRSNTGSLRTQLDEARARLEQRKKFDVLAEGITSNRMLKSRADQERNLSKLAEECAQLQEEISQNATTLRERKDQFERIMDEAHRLRRQIRDENDEVDRREGMGDDEGGEADGHTPRPGIASGNATPLPHAVPQRALAASTLGSRTPARESPAPQDSLKPTPDPVGSFSQGGGRSDSQDGAGATPAASTGAEARIGEGEGEDIEMGDVGERQPGDDGTPRNTDTQGEGTPRIMVDGPPVVEEKMDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRI5</accession>
    <name>G4MRI5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_02437</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 15 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709224.1">
        <property type="nucleotide sequence ID" value="XM_003709176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRI5"/>
    <dbReference type="STRING" id="242507.G4MRI5"/>
    <dbReference type="GeneID" id="2681534"/>
    <dbReference type="KEGG" id="mgr:MGG_02437"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02437"/>
    <dbReference type="eggNOG" id="KOG1311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024136_0_1_1"/>
    <dbReference type="InParanoid" id="G4MRI5"/>
    <dbReference type="OMA" id="GEFRFCK"/>
    <dbReference type="OrthoDB" id="302728at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="117"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="465"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="557"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA56612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="610" mass="67249" checksum="40B9624A981215E6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRK3</accession>
    <name>G4MRK3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exoribonuclease phosphorolytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_16298</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710038.1">
        <property type="nucleotide sequence ID" value="XM_003709990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRK3"/>
    <dbReference type="SMR" id="G4MRK3"/>
    <dbReference type="FunCoup" id="G4MRK3">
        <property type="interactions" value="246"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRK3"/>
    <dbReference type="GeneID" id="12985322"/>
    <dbReference type="KEGG" id="mgr:MGG_16298"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16298"/>
    <dbReference type="eggNOG" id="KOG1069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063514_2_2_1"/>
    <dbReference type="InParanoid" id="G4MRK3"/>
    <dbReference type="OMA" id="SYKCPAT"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="13"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA57426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="260" mass="27797" checksum="57A8C0E264BA0AE5" modified="2011-12-14" version="1">MPSRGEPAALVSHIPRADGSAIYSHAGYTVTASANGPIEAQRRDEDPYEALVDVIVRPAAGVGGTRERHLESLLQATLRQIILVKNFPRGLIQVVLQVKSSPENDYASTKLVQANLNLPIIPALLQAAVLALLSAAIPLRATATCTVIAVVAGSDGEAESNLILDPSPREAEGARSVHALAFTSGDRLILAESEGHFTMQEWADVHAKALKICCEPVRDPGNNDMDMGDDNSTDVEGPNMRHFIRETMAAKVSADLHWKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRN3</accession>
    <name>G4MRN3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_09958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710068.1">
        <property type="nucleotide sequence ID" value="XM_003710020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRN3"/>
    <dbReference type="GeneID" id="2680866"/>
    <dbReference type="KEGG" id="mgr:MGG_09958"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09958"/>
    <dbReference type="eggNOG" id="ENOG502SYS1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089720_1_1_1"/>
    <dbReference type="InParanoid" id="G4MRN3"/>
    <dbReference type="OMA" id="MSIVTHG"/>
    <dbReference type="OrthoDB" id="2129069at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="214" mass="23782" checksum="616CB8903BD86E50" modified="2011-12-14" version="1">MTARFSSTLRSRPVWISAVDVLYKAPPGTKWMESKMEAQDLVVSSTTTGSTDSEACFRFLLLSPAELDNPATQIRLERFCNLTAHTAIVFLDEAESTAFVDFQIRMIQSKLDVPVVPIKSTAALPGTVTAFHERFSAAQPRISKPQAVRALLPFCTVNPPIREHNFNMLSDIVPSFKVMIEVISTRQGQDELCSYIGQSDASDVIKFWTAEYTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRR0</accession>
    <name>G4MRR0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nitrate/nitrite transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_13793</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710887.1">
        <property type="nucleotide sequence ID" value="XM_003710839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRR0"/>
    <dbReference type="STRING" id="242507.G4MRR0"/>
    <dbReference type="GeneID" id="5049012"/>
    <dbReference type="KEGG" id="mgr:MGG_13793"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13793"/>
    <dbReference type="eggNOG" id="ENOG502QPIC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024204_1_1_1"/>
    <dbReference type="InParanoid" id="G4MRR0"/>
    <dbReference type="OMA" id="TFWAWNL"/>
    <dbReference type="OrthoDB" id="434240at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015113">
        <property type="term" value="F:nitrite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004737">
        <property type="entry name" value="NO3_transporter_NarK/NarU-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00886">
        <property type="entry name" value="2A0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="38"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="259"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="279"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA58275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="533" mass="57072" checksum="D922885AE1B79582" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRU9</accession>
    <name>G4MRU9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710926.1">
        <property type="nucleotide sequence ID" value="XM_003710878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRU9"/>
    <dbReference type="GeneID" id="12986864"/>
    <dbReference type="KEGG" id="mgr:MGG_16517"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16517"/>
    <dbReference type="HOGENOM" id="CLU_2134000_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRU9"/>
    <dbReference type="OrthoDB" id="10371642at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="113" mass="12776" checksum="809A3A2BC06D4A02" modified="2011-12-14" version="1">MNASPDESGRNVDWPSPRAEQLPRFFDPESPGGGINCSTDLYVQAIMLGSRSKGKQEYQRENRDHGEGCIRKSIVLSNPSTIVVEYLRKYASRRMGGRIPLIPQNKLGWQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS09</accession>
    <name>G4MS09_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="5 17">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MGG_10655</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 17">
            <text>2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 17">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the ALAD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="5 17"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710087.1">
        <property type="nucleotide sequence ID" value="XM_003710039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS09"/>
    <dbReference type="SMR" id="G4MS09"/>
    <dbReference type="FunCoup" id="G4MS09">
        <property type="interactions" value="623"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MS09"/>
    <dbReference type="GeneID" id="2682268"/>
    <dbReference type="KEGG" id="mgr:MGG_10655"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10655"/>
    <dbReference type="eggNOG" id="KOG2794">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035731_0_1_1"/>
    <dbReference type="InParanoid" id="G4MS09"/>
    <dbReference type="OMA" id="YQMDYAN"/>
    <dbReference type="OrthoDB" id="1530at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04824">
        <property type="entry name" value="eu_ALAD_PBGS_cysteine_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000048">
        <property type="entry name" value="Delta-aminolevulinic acid dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006762">
        <property type="entry name" value="PRK09283.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458:SF0">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="10 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 17" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="14">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="14">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EHA57475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="389" mass="42174" checksum="FE865FCC2E9BF2AE" modified="2011-12-14" version="1">MSFSSLVQDLSLRDANGARRRGLPRGDSSAPTIDDGASRTSHISRAMSYASTAATSVSISGDISSQLHGGYSHPLARSWQAERQLTKSMLIYPLFISDSDDEEVLIPSLPDQYRRGINKVIPFLETLVHKGLRSVILFGVPMRPGTKDALGTSADDPQGPVMRSIRAIRQRFPQLFVVCDVCLCEYTSHGHCGILRDDGSLNNQLSVDRISDVAVAYARAGAHCVAPSDMNDGRIRAIKLKLIEEGIAHNTLLMSYAAKFSGCLYGPFRDAAGSAPSFGDRKCYQLPHGGRGLARRAIIRDINEGADVIMVKPASQYLDIISDAKDLGKDLPIAAYQVSGEYAMIHAAAKAGVFDLKTMAFESTEGILRAGATIVVSYFTPEFLDWLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS16</accession>
    <name>G4MS16_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_10660</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710094.1">
        <property type="nucleotide sequence ID" value="XM_003710046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS16"/>
    <dbReference type="SMR" id="G4MS16"/>
    <dbReference type="STRING" id="242507.G4MS16"/>
    <dbReference type="GeneID" id="2682273"/>
    <dbReference type="KEGG" id="mgr:MGG_10660"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10660"/>
    <dbReference type="eggNOG" id="ENOG502SG5D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_852774_0_0_1"/>
    <dbReference type="InParanoid" id="G4MS16"/>
    <dbReference type="OrthoDB" id="2257100at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="262"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="194"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="287"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA57482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="326" mass="35803" checksum="0035B2B11814DFC7" modified="2011-12-14" version="1">MARVNTFSHSQNRFNPGDPWGAGVRIESIDGSSKAKRKYFERNEAILQPPSPPSWQCSSVPTSAEDVSGLASLIHDAHYQSVGVGGLTLDDFVAQSLSLEPATTSFDFHQFNQDADNHSHLQQDSSITTAVDTAILDPSFWDPTLILDPSIASEISLFPTIQQHSSSVSPVDSFLTLDTPSLASSVSSLSPKEFASSEFGDAPATNKSHHARENKSAGGTDNKKKVTKDKMAPAMSVFSVKTSVAGRKRTRDAQATPEENEDEILADKRRRNNAAAAKYRQKKVDRISELEDCVAEISKERDDLKLQLAKRDEEIRILREMLMGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSL1</accession>
    <name>G4MSL1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NDT80 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_01475</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714434.1">
        <property type="nucleotide sequence ID" value="XM_003714386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSL1"/>
    <dbReference type="SMR" id="G4MSL1"/>
    <dbReference type="FunCoup" id="G4MSL1">
        <property type="interactions" value="1136"/>
    </dbReference>
    <dbReference type="GeneID" id="2679669"/>
    <dbReference type="KEGG" id="mgr:MGG_01475"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01475"/>
    <dbReference type="eggNOG" id="ENOG502R1FS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026383_1_1_1"/>
    <dbReference type="InParanoid" id="G4MSL1"/>
    <dbReference type="OMA" id="VWTCYRR"/>
    <dbReference type="OrthoDB" id="2288358at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF2">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="94"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="94"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="237"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="362"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="423"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA54627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="550" mass="60137" checksum="0A252186049BAD51" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSW9</accession>
    <name>G4MSW9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="8">ATase</shortName>
            <ecNumber evidence="3 8">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_04618</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3 8"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713630.1">
        <property type="nucleotide sequence ID" value="XM_003713582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSW9"/>
    <dbReference type="SMR" id="G4MSW9"/>
    <dbReference type="FunCoup" id="G4MSW9">
        <property type="interactions" value="711"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSW9"/>
    <dbReference type="MEROPS" id="C44.001"/>
    <dbReference type="GeneID" id="2677934"/>
    <dbReference type="KEGG" id="mgr:MGG_04618"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04618"/>
    <dbReference type="eggNOG" id="KOG0572">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022389_2_1_1"/>
    <dbReference type="InParanoid" id="G4MSW9"/>
    <dbReference type="OMA" id="IRHFGVK"/>
    <dbReference type="OrthoDB" id="191723at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="PHI-base" id="PHI:123405"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046083">
        <property type="term" value="P:adenine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 8 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="12">
        <location>
            <begin position="2"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="505"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA53823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="537" mass="58574" checksum="9E5B291227AB37DC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT13</accession>
    <name>G4MT13_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714479.1">
        <property type="nucleotide sequence ID" value="XM_003714431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT13"/>
    <dbReference type="SMR" id="G4MT13"/>
    <dbReference type="FunCoup" id="G4MT13">
        <property type="interactions" value="55"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MT13"/>
    <dbReference type="GeneID" id="2679272"/>
    <dbReference type="KEGG" id="mgr:MGG_01508"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01508"/>
    <dbReference type="eggNOG" id="ENOG502RXYC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059017_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT13"/>
    <dbReference type="OMA" id="NIMFATR"/>
    <dbReference type="OrthoDB" id="5549748at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd07600">
        <property type="entry name" value="BAR_Gvp36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018859">
        <property type="entry name" value="BAR_dom-cont"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10455">
        <property type="entry name" value="BAR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="35734" checksum="5572DC5D12C69B7C" modified="2011-12-14" version="1">MDFKNFGKNITSLGASFTPFASRTFQYTKEQLGQVEDKTQLPPDYIDLEKRVDALKAVHQKMLAVTNQYATEAYDYPPNIKETFSDLGRTVSEKVTLLSSATSPAEAQAALTAPPSAKPQPKTFSHAIARASLASSQTLHQTHADAGEDPLATALEKYALAQERVGEARLAQDNQIQRSFLAGWNTTLNTNLLFATRARKNVENSRLSLDAAKARAKGTTWKLPATTSPRGDAAAHHEEPELSPEAQEEIEKAEDEFVTQTEEAVGVMKNVLDTPEPLRNLAELVAAQMEYHKKAHEILSELAPLIEGLQVEQEASYRKSRESAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTB1</accession>
    <name>G4MTB1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_04669</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713664.1">
        <property type="nucleotide sequence ID" value="XM_003713616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTB1"/>
    <dbReference type="STRING" id="242507.G4MTB1"/>
    <dbReference type="GeneID" id="2678099"/>
    <dbReference type="KEGG" id="mgr:MGG_04669"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04669"/>
    <dbReference type="eggNOG" id="ENOG502SCDZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007077_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTB1"/>
    <dbReference type="OMA" id="IFQVLWG"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140575">
        <property type="term" value="F:transmembrane monodehydroascorbate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF24">
        <property type="entry name" value="DOMON RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="67"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="236"/>
            <end position="264"/>
        </location>
    </feature>
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        </location>
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            <end position="498"/>
        </location>
    </feature>
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        <location>
            <begin position="511"/>
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        </location>
    </feature>
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            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="466"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="566"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="595"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="664"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
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            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
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            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="817"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA53857.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="873" mass="94932" checksum="B7B8F663131746D0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTE4</accession>
    <name>G4MTE4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA54695.1"/>
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    <dbReference type="Proteomes" id="UP000009058">
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="53"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54695.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="133" mass="14499" checksum="E77C476460229D0F" modified="2011-12-14" version="1">MIDANGRTLRRRRRIPLDPEVKDGIVQFDAMSSPIDSTESESESNIGRACPIPKPGGKVGELLGFTRKQPPSQDENKTQVDRGASTAVGTIKDQSGRHIEKEMRRLPMACHVKSSLMIVGPMIAILAESCRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2024-01-24" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTL5</accession>
    <name>G4MTL5_PYRO7</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003715332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTL5"/>
    <dbReference type="GeneID" id="12986665"/>
    <dbReference type="KEGG" id="mgr:MGG_15871"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15871"/>
    <dbReference type="InParanoid" id="G4MTL5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="49" mass="5657" checksum="102EB03B6907A7BE" modified="2011-12-14" version="1" fragment="single">LQTHPRLVLTSFAFLRVVMVARGCVLWRQNQLRQVKVGGAKKSRRHSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTS9</accession>
    <name>G4MTS9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">MGG_04773</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22980"/>
            <dbReference type="Rhea" id="RHEA-COMP:12804"/>
            <dbReference type="Rhea" id="RHEA-COMP:12805"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="Rhea" id="RHEA-COMP:19509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:50347"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57570"/>
            <dbReference type="ChEBI" id="CHEBI:132529"/>
            <dbReference type="EC" id="2.4.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.18" evidence="6"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713725.1">
        <property type="nucleotide sequence ID" value="XM_003713677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTS9"/>
    <dbReference type="SMR" id="G4MTS9"/>
    <dbReference type="FunCoup" id="G4MTS9">
        <property type="interactions" value="985"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTS9"/>
    <dbReference type="GeneID" id="2677899"/>
    <dbReference type="KEGG" id="mgr:MGG_04773"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04773"/>
    <dbReference type="eggNOG" id="KOG2292">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009279_1_0_1"/>
    <dbReference type="InParanoid" id="G4MTS9"/>
    <dbReference type="OMA" id="TWYAIGT"/>
    <dbReference type="OrthoDB" id="10261066at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004579">
        <property type="term" value="F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043687">
        <property type="term" value="P:post-translational protein modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12610:FF:000001">
        <property type="entry name" value="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003674">
        <property type="entry name" value="Oligo_trans_STT3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048999">
        <property type="entry name" value="STT3-PglB_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048307">
        <property type="entry name" value="STT3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872:SF1">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02516">
        <property type="entry name" value="STT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21436">
        <property type="entry name" value="STT3-PglB_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16" id="KW-0464">Manganese</keyword>
    <keyword evidence="14 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="173"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="301"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Oligosaccharyl transferase STT3 N-terminal" evidence="22">
        <location>
            <begin position="20"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="STT3/PglB/AglB core" evidence="23">
        <location>
            <begin position="545"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="730"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="20">
        <location>
            <begin position="732"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00059243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00067960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF02516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF21436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="EHA53918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="750" mass="83679" checksum="BCEDED906029E222" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTU9</accession>
    <name>G4MTU9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="13">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MGG_01572</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:21249"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="13"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714550.1">
        <property type="nucleotide sequence ID" value="XM_003714502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTU9"/>
    <dbReference type="SMR" id="G4MTU9"/>
    <dbReference type="FunCoup" id="G4MTU9">
        <property type="interactions" value="946"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTU9"/>
    <dbReference type="GeneID" id="2679518"/>
    <dbReference type="KEGG" id="mgr:MGG_01572"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01572"/>
    <dbReference type="eggNOG" id="KOG0216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_5_1_1"/>
    <dbReference type="InParanoid" id="G4MTU9"/>
    <dbReference type="OMA" id="FFGVVHY"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000016">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000007">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009674">
        <property type="entry name" value="Rpa2_dom_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06883">
        <property type="entry name" value="RNA_pol_Rpa2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13 21" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="18">
        <location>
            <begin position="39"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="201"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="19">
        <location>
            <begin position="489"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase I subunit RPA2" evidence="20">
        <location>
            <begin position="594"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="15">
        <location>
            <begin position="701"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="1079"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1209"/>
            <end position="1229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF06883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EHA54743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1240" mass="138803" checksum="EB11EB34D0FCCFD2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTY8</accession>
    <name>G4MTY8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01605</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714589.1">
        <property type="nucleotide sequence ID" value="XM_003714541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTY8"/>
    <dbReference type="SMR" id="G4MTY8"/>
    <dbReference type="STRING" id="242507.G4MTY8"/>
    <dbReference type="GeneID" id="2679461"/>
    <dbReference type="KEGG" id="mgr:MGG_01605"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01605"/>
    <dbReference type="eggNOG" id="KOG3855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_9_3_1"/>
    <dbReference type="InParanoid" id="G4MTY8"/>
    <dbReference type="OMA" id="IYDIAFW"/>
    <dbReference type="OrthoDB" id="5325318at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02979">
        <property type="entry name" value="PHOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF4">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="40"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="6">
        <location>
            <begin position="427"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="652" mass="73333" checksum="E732E8F6B5F913F5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU49</accession>
    <name>G4MU49_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RPEL repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_07237</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715456.1">
        <property type="nucleotide sequence ID" value="XM_003715408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU49"/>
    <dbReference type="SMR" id="G4MU49"/>
    <dbReference type="STRING" id="242507.G4MU49"/>
    <dbReference type="GeneID" id="2683125"/>
    <dbReference type="KEGG" id="mgr:MGG_07237"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07237"/>
    <dbReference type="eggNOG" id="ENOG502SC67">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121574_0_0_1"/>
    <dbReference type="InParanoid" id="G4MU49"/>
    <dbReference type="OMA" id="ENHLMHR"/>
    <dbReference type="OrthoDB" id="197676at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043451">
        <property type="entry name" value="Myocardin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004018">
        <property type="entry name" value="RPEL_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793:SF12">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02755">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00707">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51073">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="13662" checksum="CBEDF7491D1D9930" modified="2011-12-14" version="1">MAEDNKNIESQPAVDETPISPSRPNQRRKNSLEEHLKNRPERAELVDRNILPASTAAPALQEKQKELAKHMRADSLNEKIAHRPSPDELIKKGVLDEDPRTAEEKYAEAIEDEYAKREGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUK8</accession>
    <name>G4MUK8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 13">Cytochrome c oxidase subunit 6, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Cytochrome c oxidase polypeptide VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_15895</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion inner membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytochrome c oxidase subunit 5A family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715507.1">
        <property type="nucleotide sequence ID" value="XM_003715459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUK8"/>
    <dbReference type="SMR" id="G4MUK8"/>
    <dbReference type="FunCoup" id="G4MUK8">
        <property type="interactions" value="473"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUK8"/>
    <dbReference type="GeneID" id="12986693"/>
    <dbReference type="KEGG" id="mgr:MGG_15895"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15895"/>
    <dbReference type="eggNOG" id="KOG4077">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099086_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUK8"/>
    <dbReference type="OMA" id="MEKWPAD"/>
    <dbReference type="OrthoDB" id="5778907at2759"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00923">
        <property type="entry name" value="Cyt_c_Oxidase_Va"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.40:FF:000001">
        <property type="entry name" value="Cytochrome c oxidase subunit VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.40">
        <property type="entry name" value="Cytochrome c oxidase, subunit Va/VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003204">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036545">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200:SF11">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02284">
        <property type="entry name" value="COX5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48479">
        <property type="entry name" value="Cytochrome c oxidase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0349">Heme</keyword>
    <keyword evidence="8 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00070174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00082700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA55700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="167" mass="18435" checksum="EDE7D806AD8EF5B8" modified="2011-12-14" version="1">MSASLLRIAARGPATAFLRTHAVARPSMAARAAIIAPALSAVNSNNSFSSSARLRAGPHAEETFEEFSARYEQEFEAVQDVFELQRNLNNAFAYDLVPSPEVLKAALKAARRVNDFATAVRIFEGIKAKVENDGQYKQYLEELKPLREELGIPLKEDLYPEGEEAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUT9</accession>
    <name>G4MUT9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_11167</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714676.1">
        <property type="nucleotide sequence ID" value="XM_003714628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUT9"/>
    <dbReference type="SMR" id="G4MUT9"/>
    <dbReference type="STRING" id="242507.G4MUT9"/>
    <dbReference type="GeneID" id="5051139"/>
    <dbReference type="KEGG" id="mgr:MGG_11167"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11167"/>
    <dbReference type="eggNOG" id="KOG0027">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061288_2_1_1"/>
    <dbReference type="InParanoid" id="G4MUT9"/>
    <dbReference type="OMA" id="EEFQIAM"/>
    <dbReference type="OrthoDB" id="5214543at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="9"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="94"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="161" mass="17781" checksum="FECBD6733834C185" modified="2011-12-14" version="1">MPAQTLSNDQLKQLKDVFDLIDKDGTGAISASEFAEAMESLGLSSSAAEAQEIISEIDQNKDGQIDFHEFLRVMSHPETHDALSPNERSKDSKKDERELLAAFKVFDSDGSGSISPEELRHALRPLGYTPAEIDEMIAHADLDGNGSIDYQEFVELMSQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV11</accession>
    <name>G4MV11_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715552.1">
        <property type="nucleotide sequence ID" value="XM_003715504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV11"/>
    <dbReference type="GeneID" id="5050994"/>
    <dbReference type="KEGG" id="mgr:MGG_12400"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12400"/>
    <dbReference type="HOGENOM" id="CLU_1835532_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV11"/>
    <dbReference type="OMA" id="IYVEVEP"/>
    <dbReference type="OrthoDB" id="10489622at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="140" mass="15712" checksum="57B6162A3ACD3FAB" modified="2011-12-14" version="1">MDDSQGKRQTKLRKSKAKHASRRARQVPVGCGQILVHTDAAGVDAMGCGVVRWAWWSMLDSTWAWVAIPNIYVEVEPAPSRELGTGEEKRSTGGEERGEMLTATGWDLVDVTLHWSLERGYSTSQSVRSKKKKKKKTKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVF9</accession>
    <name>G4MVF9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715592.1">
        <property type="nucleotide sequence ID" value="XM_003715544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVF9"/>
    <dbReference type="GeneID" id="12986710"/>
    <dbReference type="KEGG" id="mgr:MGG_15908"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15908"/>
    <dbReference type="HOGENOM" id="CLU_2688290_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVF9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465668" evidence="1">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="74" mass="7633" checksum="902D3CF0459DAE26" modified="2011-12-14" version="1">MKLYLLLFAALAAAQVSGGDYDCDATKAKCTSDCQAKGRTVSVNICEVFEAGSHRACSCGDKEKKPGGGKDGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWX7</accession>
    <name>G4MWX7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714076.1">
        <property type="nucleotide sequence ID" value="XM_003714028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWX7"/>
    <dbReference type="SMR" id="G4MWX7"/>
    <dbReference type="GeneID" id="2679790"/>
    <dbReference type="KEGG" id="mgr:MGG_01189"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01189"/>
    <dbReference type="eggNOG" id="ENOG502S6IQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029955_1_0_1"/>
    <dbReference type="InParanoid" id="G4MWX7"/>
    <dbReference type="OMA" id="MLWLRTR"/>
    <dbReference type="OrthoDB" id="5377213at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="474" mass="50822" checksum="D5A7657932DE5315" modified="2011-12-14" version="1">MATTSSWKSSSGGHFNGTITTANGNKITKGRGRMVVKPILKKLQSGSEKNSLDLDRGWEDQQHNWNDYPASRSARDVSFTTPGFMESGDVGSLNSGPSLGGKVVDVGRPKFQHARSPSGASHASVGTTGSGTGPGRGGFVHPFQQTPRTATPPLLSYAGSMASIDAGAGGGCGRDYSPTITENEDDDYAYQTGKMHPYSMSQSSLRRPSLASQRTASFSDMHGVAQSSSNAKTSRAGSHSAAAGNSGSSRMVHGGILTSQPSQSFVASPTSSFSAAPLSPLRTSLEMGLGGLAPRLRSLSEQQETRGKKPPSLSDPAEHTRLMRERRAKFDEKERLKAEKAARKQHKHSASQHQSKDAEKRDLEMFQRQKHEAALYSSGSRPGTASGASIIYNRSSINRPIYGVDQFPIVTNEKIESNIDSKKGKKSGSFARGAVGAAGGFDPQQQRERKSAKNVWTNFVLWIRTTIFKLKRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXA1</accession>
    <name>G4MXA1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_08278</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715806.1">
        <property type="nucleotide sequence ID" value="XM_003715758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXA1"/>
    <dbReference type="SMR" id="G4MXA1"/>
    <dbReference type="GeneID" id="2678559"/>
    <dbReference type="KEGG" id="mgr:MGG_08278"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08278"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010365_5_1_1"/>
    <dbReference type="InParanoid" id="G4MXA1"/>
    <dbReference type="OMA" id="HPFTIFS"/>
    <dbReference type="OrthoDB" id="17725at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF28">
        <property type="entry name" value="FRP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="340"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="67"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA55999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="639" mass="70805" checksum="64F12F3A6A1F4D0D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY38</accession>
    <name>G4MY38_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714176.1">
        <property type="nucleotide sequence ID" value="XM_003714128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY38"/>
    <dbReference type="SMR" id="G4MY38"/>
    <dbReference type="STRING" id="242507.G4MY38"/>
    <dbReference type="CAZy" id="GH15">
        <property type="family name" value="Glycoside Hydrolase Family 15"/>
    </dbReference>
    <dbReference type="GeneID" id="2679648"/>
    <dbReference type="KEGG" id="mgr:MGG_01264"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01264"/>
    <dbReference type="eggNOG" id="ENOG502QS7A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010399_2_0_1"/>
    <dbReference type="InParanoid" id="G4MY38"/>
    <dbReference type="OMA" id="VEWMCVP"/>
    <dbReference type="OrthoDB" id="406733at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF0">
        <property type="entry name" value="GLUCAN 1,4-ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="TREH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trehalase-like N-terminal" evidence="2">
        <location>
            <begin position="24"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="GH15-like" evidence="1">
        <location>
            <begin position="304"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="694" mass="78566" checksum="D5F51DAB00E0D6A0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY59</accession>
    <name>G4MY59_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_01279</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714197.1">
        <property type="nucleotide sequence ID" value="XM_003714149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY59"/>
    <dbReference type="SMR" id="G4MY59"/>
    <dbReference type="FunCoup" id="G4MY59">
        <property type="interactions" value="211"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MY59"/>
    <dbReference type="GeneID" id="2679445"/>
    <dbReference type="KEGG" id="mgr:MGG_01279"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01279"/>
    <dbReference type="eggNOG" id="KOG0583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002664_0_2_1"/>
    <dbReference type="InParanoid" id="G4MY59"/>
    <dbReference type="OMA" id="NSADYRP"/>
    <dbReference type="OrthoDB" id="1928777at2759"/>
    <dbReference type="PHI-base" id="PHI:3179"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
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    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
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            <begin position="154"/>
            <end position="418"/>
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            <begin position="999"/>
            <end position="1048"/>
        </location>
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            <begin position="1"/>
            <end position="141"/>
        </location>
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            <begin position="479"/>
            <end position="527"/>
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            <begin position="126"/>
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            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
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        <location>
            <begin position="647"/>
            <end position="658"/>
        </location>
    </feature>
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        <location>
            <begin position="668"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
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            <begin position="768"/>
            <end position="783"/>
        </location>
    </feature>
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            <end position="797"/>
        </location>
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            <begin position="815"/>
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        </location>
    </feature>
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        <location>
            <begin position="975"/>
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        </location>
    </feature>
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        <location>
            <position position="183"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
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            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA54390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1048" mass="116134" checksum="A09C6C8A10B4A53F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYG2</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">MGG_10485</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003713341.1"/>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
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        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="621"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="749" mass="81646" checksum="F37EB4F2468AD5F5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYK1</accession>
    <name>G4MYK1_PYRO7</name>
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        <recommendedName>
            <fullName evidence="19">Histidine biosynthesis trifunctional protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-AMP cyclohydrolase</fullName>
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            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-ATP pyrophosphohydrolase</fullName>
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            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Histidinol dehydrogenase</fullName>
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                <ecNumber evidence="19">1.1.1.23</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="22" type="ORF">MGG_01309</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 19">In the C-terminal section; belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="19"/>
    <dbReference type="EC" id="3.6.1.31" evidence="19"/>
    <dbReference type="EC" id="1.1.1.23" evidence="19"/>
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        <property type="protein sequence ID" value="EHA54426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714233.1">
        <property type="nucleotide sequence ID" value="XM_003714185.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MYK1"/>
    <dbReference type="SMR" id="G4MYK1"/>
    <dbReference type="FunCoup" id="G4MYK1">
        <property type="interactions" value="339"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYK1"/>
    <dbReference type="GeneID" id="2679590"/>
    <dbReference type="KEGG" id="mgr:MGG_01309"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01309"/>
    <dbReference type="eggNOG" id="KOG2697">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4311">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006732_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYK1"/>
    <dbReference type="OMA" id="SVFIGAW"/>
    <dbReference type="OrthoDB" id="1703565at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11546">
        <property type="entry name" value="NTP-PPase_His4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1080:FF:000002">
        <property type="entry name" value="Histidine biosynthesis bifunctional protein HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1300:FF:000001">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.810:FF:000002">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000050">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000001">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="entry name" value="Phosphoribosyl-AMP cyclohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016298">
        <property type="entry name" value="Histidine_synth_trifunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF2">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS TRIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001257">
        <property type="entry name" value="His_trifunctional"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="HisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16 19" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15 19" id="KW-0520">NAD</keyword>
    <keyword evidence="10 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphoribosyl-AMP cyclohydrolase" evidence="21">
        <location>
            <begin position="220"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="386"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR001257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EHA54426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="865" mass="92591" checksum="63E5BB00EEFED865" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYL8</accession>
    <name>G4MYL8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NIMA-interacting protein TinC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714250.1">
        <property type="nucleotide sequence ID" value="XM_003714202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYL8"/>
    <dbReference type="STRING" id="242507.G4MYL8"/>
    <dbReference type="GeneID" id="2679538"/>
    <dbReference type="KEGG" id="mgr:MGG_01326"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01326"/>
    <dbReference type="eggNOG" id="ENOG502QRXF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010063_1_0_1"/>
    <dbReference type="InParanoid" id="G4MYL8"/>
    <dbReference type="OMA" id="VQDCGHG"/>
    <dbReference type="OrthoDB" id="2506204at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010816">
        <property type="entry name" value="Het-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052577">
        <property type="entry name" value="VWA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905">
        <property type="entry name" value="NG37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905:SF11">
        <property type="entry name" value="TINC (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07217">
        <property type="entry name" value="Het-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465532" evidence="2">
        <location>
            <begin position="26"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="684"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="695"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="759" mass="85273" checksum="D5CAFBE1BA601FCF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYW0</accession>
    <name>G4MYW0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peroxisomal membrane protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14731</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713428.1">
        <property type="nucleotide sequence ID" value="XM_003713380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYW0"/>
    <dbReference type="STRING" id="242507.G4MYW0"/>
    <dbReference type="GeneID" id="5049426"/>
    <dbReference type="KEGG" id="mgr:MGG_14731"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14731"/>
    <dbReference type="eggNOG" id="ENOG502RXMH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054132_1_0_1"/>
    <dbReference type="InParanoid" id="G4MYW0"/>
    <dbReference type="OMA" id="VMVFLFR"/>
    <dbReference type="OrthoDB" id="39659at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019531">
        <property type="entry name" value="Pmp4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15460">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15460:SF3">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF013674">
        <property type="entry name" value="PXMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="225" mass="25185" checksum="26D29314C44764A3" modified="2011-12-14" version="1">MAAAIQSLQASLERVILNPRYHDLLAVVKGARNGAVYGTKVRFPHALVMILLFRSGTLREKLWLVFRATRTHARNLAKFVTIYKFTCFLLKHYGPTPGKEGPYDTFVAGMLGGYLVFGGRSGRTGKISSVNQQIVVYVFARVVLALARLAVKPGFGLPVVSEPGNSAAISYYAWPVFAATSWGLVMHLFRYHAAELQPSLRSSMTYLYLQSNEWDGLRNFLWHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZN5</accession>
    <name>G4MZN5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pali-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715206.1">
        <property type="nucleotide sequence ID" value="XM_003715158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZN5"/>
    <dbReference type="GeneID" id="2683038"/>
    <dbReference type="KEGG" id="mgr:MGG_07024"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07024"/>
    <dbReference type="eggNOG" id="ENOG502S0K3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076420_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZN5"/>
    <dbReference type="OMA" id="FGTFGWC"/>
    <dbReference type="OrthoDB" id="2354757at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035838">
        <property type="term" value="C:growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051380">
        <property type="entry name" value="pH-response_reg_palI/RIM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013:SF7">
        <property type="entry name" value="PALI-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="24877" checksum="6738B8002D85FBE2" modified="2011-12-14" version="1">MAATSHKIGTFFLLGAVALLAVTNITAPVVKSISLLKININHTTASPDQHPVLVLGTYGYCITNSTSSHGSNNANTTVSENNNGTMKSSTDGNHCSPVQFGYNTVSVVGEAAGLQFTPSALDTGAATSKLTVLHPIAAGTSALAALLSLGAGSSGSCTAFFMTLLALCSTITALVVDYVVLNMIRAGLTETPAAGASAEFGAGMWTLLGAAGLLGLGTVMSLFACCGGSRRSRRDDRYSKEIDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N012</accession>
    <name>G4N012_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712057.1">
        <property type="nucleotide sequence ID" value="XM_003712009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N012"/>
    <dbReference type="SMR" id="G4N012"/>
    <dbReference type="STRING" id="242507.G4N012"/>
    <dbReference type="GeneID" id="2684315"/>
    <dbReference type="KEGG" id="mgr:MGG_06175"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06175"/>
    <dbReference type="eggNOG" id="KOG0191">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021868_0_0_1"/>
    <dbReference type="InParanoid" id="G4N012"/>
    <dbReference type="OMA" id="IFVYFYD"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052250">
        <property type="entry name" value="PDI_TMX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426:SF1">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005680486" description="Thioredoxin domain-containing protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="669"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="17"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="246"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="156"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA52250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="722" mass="81664" checksum="C01C0B070DA05989" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N065</accession>
    <name>G4N065_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07704</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase M14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712907.1">
        <property type="nucleotide sequence ID" value="XM_003712859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N065"/>
    <dbReference type="SMR" id="G4N065"/>
    <dbReference type="GeneID" id="2683631"/>
    <dbReference type="KEGG" id="mgr:MGG_07704"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07704"/>
    <dbReference type="eggNOG" id="KOG2650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018931_0_0_1"/>
    <dbReference type="InParanoid" id="G4N065"/>
    <dbReference type="OMA" id="ETKNHVS"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000155">
        <property type="entry name" value="Zn-dependent exopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012429412" evidence="8">
        <location>
            <begin position="16"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="9">
        <location>
            <begin position="68"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="443" mass="48214" checksum="23D56699D6A650A7" modified="2011-12-14" version="1">MKLFTISALASLTWACVLPEERIAGPSSRLSRRQIMGNTGIPVGTGDRFNDGKELPLGVGTQNKAVTSVLSVKEIDSGFRALASHYKFQTFEAPQKTYEGRSVYGGKVGGNGTCDDAYRVYLNGAIHARERGSADGVLFFVADLLYANEKNTGITYGRKSYSNADVKKALSAGLVFVPLSNPDGVAYDQASNSCWRKNRNPRSARAGDDSTIGVDLNRNFDFLWDFPKEFAPSVASSVASTDPGSEVFHGTSAFSEPETQNIKWVLDTYKKVRWFVDLHSYTGDVLYSWGSDTNQEKYDYMNFHNSSYNAVRGLVNDVPGRGRGYGEYTPAGEDSVNQGAAKRMGNAMSAANGRTYTVSQAVGLYPTSGSSDDYSYSRHFTDPSKNLVHGYTVEFGFGNNAVPDCPFYPSESQHNDNLREIGAGFMETLLAAVDLGLGDATKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0N0</accession>
    <name>G4N0N0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_16921</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712968.1">
        <property type="nucleotide sequence ID" value="XM_003712920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0N0"/>
    <dbReference type="FunCoup" id="G4N0N0">
        <property type="interactions" value="478"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N0N0"/>
    <dbReference type="GeneID" id="12985878"/>
    <dbReference type="KEGG" id="mgr:MGG_16921"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16921"/>
    <dbReference type="eggNOG" id="KOG1590">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099502_3_0_1"/>
    <dbReference type="InParanoid" id="G4N0N0"/>
    <dbReference type="OMA" id="CTTHFWG"/>
    <dbReference type="OrthoDB" id="1697690at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="136" mass="14856" checksum="A6FEC7A638C53587" modified="2011-12-14" version="1">MAAFVKSINARIRANKVLDYVCSTHFWGPVSTFGIPIAAIADIQRAPADKISLPMTCALAGYSGVFMRFAFAVTPKNYLLFATHVVNSTAQLTQGYRYFQYHYGGGKERPAAQEAAVSGYVSKEEIKDAAAILVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1J2</accession>
    <name>G4N1J2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_07830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713066.1">
        <property type="nucleotide sequence ID" value="XM_003713018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1J2"/>
    <dbReference type="SMR" id="G4N1J2"/>
    <dbReference type="GeneID" id="2683757"/>
    <dbReference type="KEGG" id="mgr:MGG_07830"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07830"/>
    <dbReference type="eggNOG" id="ENOG502RNYP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008719_0_1_1"/>
    <dbReference type="InParanoid" id="G4N1J2"/>
    <dbReference type="OMA" id="LEYHATE"/>
    <dbReference type="OrthoDB" id="407832at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA53259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="473" mass="52300" checksum="79A0FDB4E87BDF44" modified="2011-12-14" version="1">MPRIFNQAACNTCRVRKIKCDESLPICQRCSKASRYCDRSAAPPLPVLVQPTNTQDVFPSPSDPRRALTNPAIARYFHHYITSIAPWYDLSDGSQHFATRLPELALASALPFAAVVALAAIQISQTTAPSARAAAEYYHDHCVRLLLARLKDDNAARGDGDGDGDGNGNGNSNSNGITLASICLLRSYEILSEEVDPNRHLRGAYSLAVSRRPLLREGDLGGRGGLRGAGFWNYLREDITFSLFQRCPLKMGLDQVELFVWRGDDADGDHAYLNAVSLILGRIINECFGRETLSPEAWDFLFRLLRDWCSALLGRFAPFAREERRLGLALPSVWMLHDCHASARHYRLVCIAILCNHASTSEQISDLISLLEDLISLLEASQDVDQCTTREEILERCAVEICGIAFTANSPPVVVNCFGPIAFCGPFIRDEAAQQELVRRLMACKRTIGWPVQRLVADLQLAWGEAAGQQIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1Q1</accession>
    <name>G4N1Q1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_07517</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711430.1">
        <property type="nucleotide sequence ID" value="XM_003711382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1Q1"/>
    <dbReference type="SMR" id="G4N1Q1"/>
    <dbReference type="GeneID" id="2683437"/>
    <dbReference type="KEGG" id="mgr:MGG_07517"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07517"/>
    <dbReference type="eggNOG" id="ENOG502S3IW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012260_2_0_1"/>
    <dbReference type="InParanoid" id="G4N1Q1"/>
    <dbReference type="OMA" id="ITHTYIQ"/>
    <dbReference type="OrthoDB" id="447251at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF9">
        <property type="entry name" value="PAS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0157">Chromophore</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="406"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="70"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="543"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="711"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="769"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="770"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA51623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="788" mass="86139" checksum="F92D3D708917894A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1Y2</accession>
    <name>G4N1Y2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713099.1">
        <property type="nucleotide sequence ID" value="XM_003713051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1Y2"/>
    <dbReference type="GeneID" id="12986048"/>
    <dbReference type="KEGG" id="mgr:MGG_16950"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16950"/>
    <dbReference type="HOGENOM" id="CLU_1855660_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1Y2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="138" mass="15338" checksum="5F3C61F89B8BFA1B" modified="2011-12-14" version="1">MADIHGIYFWDLSSPCEVGAIDVLSRTMYTREDAKGSADSLRLEENVDDKKSNGGMQDLRAQAHMMSLVVLVLYHALKCIHRVHQVAALVYQLWSKCSKALILSPSMSPKDFSNSFSKHTATRSKYFSALLSALLSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N223</accession>
    <name>G4N223_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711446.1">
        <property type="nucleotide sequence ID" value="XM_003711398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N223"/>
    <dbReference type="SMR" id="G4N223"/>
    <dbReference type="GeneID" id="2683453"/>
    <dbReference type="KEGG" id="mgr:MGG_07533"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07533"/>
    <dbReference type="HOGENOM" id="CLU_1586816_0_0_1"/>
    <dbReference type="InParanoid" id="G4N223"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="168" mass="18698" checksum="857F90FEAD1D44C5" modified="2011-12-14" version="1">MTINKNTTDIGPAVLKNTRTKKNQKRELPQLLPKNENMDGPADYKSSHVGKTWTKAAPTEMTPPPPPPPPPPPAAPASNRAARRELVLRDRQHAKLQAELGADASPSSAAKVEKALLAWERRRKRLADKRKLKLAARRIDSGIKNRTDKQEKRARRVAGSRKIKTDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N245</accession>
    <name>G4N245_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711468.1">
        <property type="nucleotide sequence ID" value="XM_003711420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N245"/>
    <dbReference type="GeneID" id="12987060"/>
    <dbReference type="KEGG" id="mgr:MGG_16653"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16653"/>
    <dbReference type="HOGENOM" id="CLU_1704580_0_0_1"/>
    <dbReference type="InParanoid" id="G4N245"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="154" mass="16534" checksum="DFDEBB462C3A9481" modified="2011-12-14" version="1">MSPLPPLSLERNLGALPTLVSFRVSVQWCAMVGALATVENWGVPKKPLSSSKRTLSQYQEKTPALVASVSSYPAKPATAGAHLDALNCHFASLVSDFLLSRAASAPHPPARFDSKRTAGLATDNGQPVGRQPRHNSLQRAHVVWSICDFFMASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2K4</accession>
    <name>G4N2K4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 14">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_07602</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 14"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711520.1">
        <property type="nucleotide sequence ID" value="XM_003711472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2K4"/>
    <dbReference type="FunCoup" id="G4N2K4">
        <property type="interactions" value="530"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N2K4"/>
    <dbReference type="GeneID" id="2683522"/>
    <dbReference type="KEGG" id="mgr:MGG_07602"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07602"/>
    <dbReference type="eggNOG" id="KOG3187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034302_6_1_1"/>
    <dbReference type="InParanoid" id="G4N2K4"/>
    <dbReference type="OMA" id="SEWWLMY"/>
    <dbReference type="OrthoDB" id="46988at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF3">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA51713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="226" mass="25560" checksum="B3577E93E14A40D4" modified="2011-12-14" version="1">MAKSKPASGPSSRPQRTQNPYLLLYNSASFLLWSYILVTAFTTYLSAGNAAVWNRLHLAVRWTETLAALEIAHAIFGLVRASPLTTAVQVAGRNTLVWAICRNYPDVAAANWAYTSMVIAWSVADVVRFVYFALDGVFGQVPGWLVWLRYNMFIVLYPPGILSEAWLCYKIIEPSKSRNPMYQYLLWTGITFYVPASYVLFSHMFSQRRKMAQKNAVTAKPQGKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N303</accession>
    <name>G4N303_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711569.1">
        <property type="nucleotide sequence ID" value="XM_003711521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N303"/>
    <dbReference type="GeneID" id="2683563"/>
    <dbReference type="KEGG" id="mgr:MGG_07643"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07643"/>
    <dbReference type="eggNOG" id="ENOG502SJAM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_912166_0_0_1"/>
    <dbReference type="InParanoid" id="G4N303"/>
    <dbReference type="OMA" id="FTGHNKT"/>
    <dbReference type="OrthoDB" id="4148174at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466049" evidence="1">
        <location>
            <begin position="24"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="313" mass="34027" checksum="094B7B999D0291E3" modified="2011-12-14" version="1">MKCFATRALTLAVSFIGCTSVLAQTQAGSRNDEGYIGYTLEQNGDPEAAVYQTSNTDTSGGIELPEEPDVYLNASVSVQEISIEVENITAKVNLDAQVLKLLHFTAGVDASIDRVKLSIQNVSAKVELEARLGNLLQMVNDVLDSIDLNPIVATLGNTVGGVINDTVGVITDPVDESGLSKRSLEYHLAYNILFSVNNYSGHNHRNRVLAQNGTMYDVYLNDRGDEISRSVAGYYSRDMTFTGHNKTISIDGEPMEFEMQYVYQPYMGLDIVSLIYMDAKNGRITRTKVVAGMEGGGSTTFKGDAGFDIKSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N318</accession>
    <name>G4N318_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711584.1">
        <property type="nucleotide sequence ID" value="XM_003711536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N318"/>
    <dbReference type="SMR" id="G4N318"/>
    <dbReference type="STRING" id="242507.G4N318"/>
    <dbReference type="GeneID" id="12984149"/>
    <dbReference type="KEGG" id="mgr:MGG_15215"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15215"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_6_3_1"/>
    <dbReference type="InParanoid" id="G4N318"/>
    <dbReference type="OMA" id="IDRTDWM"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050466">
        <property type="entry name" value="Carboxylest/Gibb_receptor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23024:SF24">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23024">
        <property type="entry name" value="ARYLACETAMIDE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="91"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="317" mass="34192" checksum="4A679920BD3B9EB5" modified="2011-12-14" version="1">MEQTTTASAKGATYTAEREQMTAKAEGAADTDRLDQTRLTIAGWEQAGIAALAPISKSITETWVDITLPSGFISKTLVIRPAQPSPPGPLIVLFHGGGFMGGSPAMITRPGREYAEQFGATVVSPTYKLLPEHAWPAGPESAWEVLAWLAENAHEGGDERFAADLDRGFVVGGFSAGASIATIIAGISLRAGLLRHDQQELAKPITGVFANCPVLLKDKDMVPDEYRKLWTSRIDNRDAPGLNTEGVEMVGKHDPLRDDGIVFEKALAARGVETKIDVFPDDGHISWVALPFEPASKDPSVEEMTMEAMRWLLGLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N379</accession>
    <name>G4N379_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SEC14 cytosolic factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712442.1">
        <property type="nucleotide sequence ID" value="XM_003712394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N379"/>
    <dbReference type="SMR" id="G4N379"/>
    <dbReference type="STRING" id="242507.G4N379"/>
    <dbReference type="GeneID" id="2675655"/>
    <dbReference type="KEGG" id="mgr:MGG_04947"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04947"/>
    <dbReference type="eggNOG" id="KOG1471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014001_4_2_1"/>
    <dbReference type="InParanoid" id="G4N379"/>
    <dbReference type="OMA" id="DWRKAND"/>
    <dbReference type="OrthoDB" id="30289at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF3">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G09260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="113"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="427" mass="47799" checksum="BBE778F5890289A7" modified="2011-12-14" version="1">MTGSTEYATGATADPEVGYPKGHLGHLTDSETKALSEFKVLVTENGLYTPGPPPSHDDQTLLRFLRARRWVPQDAFKQFKETEEWRSTTRLDTLYDTIELDSYEQSRVMYPQWTGRRDKRGIPVYLFEIKQLDSKAVAAYEKGADDTYSRAHADGSTPPKLLRLFALYENLTRFAQPLCTEMPDRPHPQTPITLSTNIVDVSGVSLRQFWNLKAHMQAASTLATAHYPETLDRIFVIGAPFFFSTVWGWIKRWFDPITVSKIFILSQAEVLPVLSSFMEVENIPKQYGGKLEFKWCDQPNLDPAIKERATWEQGFDNFPKGPVLWKVLDEERLECVAVGSVNQKQRNIRVCTLPRSFKGVVSSNQPYHKTEAAAAASDIAAVETGVQKLDIQEAKSDSEAVTSSKEEIIAEKGASSVDAPAASAKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3G7</accession>
    <name>G4N3G7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_04953</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712449.1">
        <property type="nucleotide sequence ID" value="XM_003712401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3G7"/>
    <dbReference type="SMR" id="G4N3G7"/>
    <dbReference type="FunCoup" id="G4N3G7">
        <property type="interactions" value="86"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N3G7"/>
    <dbReference type="GeneID" id="2675405"/>
    <dbReference type="KEGG" id="mgr:MGG_04953"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04953"/>
    <dbReference type="eggNOG" id="ENOG502S73N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150783_2_1_1"/>
    <dbReference type="InParanoid" id="G4N3G7"/>
    <dbReference type="OMA" id="IDIHDNA"/>
    <dbReference type="OrthoDB" id="3063237at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="97" mass="10624" checksum="EE2374EAF47979D8" modified="2011-12-14" version="1">MSEAYERERQNNARLDELSAKVSALRGVTVDIYDNARAQDVIDSTSDTFSTMGTQLKGSATRLGRMAASGNKVAVLKLSGILIAIFLVLYYGLKLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3K4</accession>
    <name>G4N3K4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712486.1">
        <property type="nucleotide sequence ID" value="XM_003712438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3K4"/>
    <dbReference type="SMR" id="G4N3K4"/>
    <dbReference type="GeneID" id="2675565"/>
    <dbReference type="KEGG" id="mgr:MGG_04986"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04986"/>
    <dbReference type="eggNOG" id="ENOG502SAQG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089389_1_0_1"/>
    <dbReference type="InParanoid" id="G4N3K4"/>
    <dbReference type="OMA" id="DRMGGLK"/>
    <dbReference type="OrthoDB" id="5388417at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="194" mass="21921" checksum="996D9D463B8DF093" modified="2011-12-14" version="1">MQITETLLAARSNIAARSPMDSEPQSENTMTLMIVLFALFFMGILMAAVLLLLRRIRLQQQMRAEGLPQYHQVAGKRDPNHRRLTIQTTPVGDGRHSVLVFRDGQPMLANPQSPPHSPDNVPQIHITFPDEHDESGRPRSGRVMLVRVGENAVGMEPLQDDEQLPAYQKENPSQFYSIDIEKIGGLKEKDQTFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N478</accession>
    <name>G4N478_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADPH-dependent FMN reductase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712605.1">
        <property type="nucleotide sequence ID" value="XM_003712557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N478"/>
    <dbReference type="SMR" id="G4N478"/>
    <dbReference type="FunCoup" id="G4N478">
        <property type="interactions" value="16"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N478"/>
    <dbReference type="GeneID" id="2675661"/>
    <dbReference type="KEGG" id="mgr:MGG_05084"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05084"/>
    <dbReference type="eggNOG" id="KOG4530">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055322_2_0_1"/>
    <dbReference type="InParanoid" id="G4N478"/>
    <dbReference type="OMA" id="VPEYNYG"/>
    <dbReference type="OrthoDB" id="68575at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050712">
        <property type="entry name" value="NAD(P)H-dep_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30543">
        <property type="entry name" value="CHROMATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30543:SF21">
        <property type="entry name" value="NAD(P)H-DEPENDENT FMN REDUCTASE LOT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADPH-dependent FMN reductase-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="208" mass="22530" checksum="BEC4DD9CA0B49B4B" modified="2011-12-14" version="1">MSAKKSIAVIAMSVRRPRVGLHVATNVHAVVSKAAGDEFAVKLVDLAEFKLPVYDEELTPAMVTDPQAQYQHEHTKRWSAEIASHDAYVLVLPEYNYSISGGAKNAIDYLYNEWIGKPIVAVTYGIFGGQHVSAAAKQILEGMKLRLAPTRPALGFVGNVAGKDFMLAADGQLGEETKNFILEGDGSKEISKSFDELKALLATPVEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5P1</accession>
    <name>G4N5P1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hemerythrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712838.1">
        <property type="nucleotide sequence ID" value="XM_003712790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5P1"/>
    <dbReference type="SMR" id="G4N5P1"/>
    <dbReference type="GeneID" id="2675361"/>
    <dbReference type="KEGG" id="mgr:MGG_05279"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05279"/>
    <dbReference type="eggNOG" id="ENOG502S4CP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074846_0_1_1"/>
    <dbReference type="InParanoid" id="G4N5P1"/>
    <dbReference type="OMA" id="LIHEGMD"/>
    <dbReference type="OrthoDB" id="10044044at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053206">
        <property type="entry name" value="Dimeric_xanthone_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38048:SF1">
        <property type="entry name" value="HEMERYTHRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin-like" evidence="2">
        <location>
            <begin position="142"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="302" mass="34857" checksum="C274F38A712F23F1" modified="2011-12-14" version="1">MSRRFLHSSAGFLFIRPIRIRPRSIPVRRLLSLQSTSDPRRPLKDRQQESARRNKAVCCGAEQSLLSKYFQFTSNIHTMSSQPVPEAAAAAPEVSQSRASGAEASCAAASEKTAVAPSAPEPEPKLPPLSAAEYREYNRLADSMEYFHNHFKQTWNMMYTAAGNNRRPANMTLRQFIDTGLAFVRQLTMHHNIEEQLLYPQLAVRMDDFRNQDGKKGGSKPSRKQSELLLQHRLIHEGMDRFEDYLTECRRGQLDFEMATLKTKMDDWNDVLWLHLDAEVETLKAENMRKYWTLPEMRRLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N620</accession>
    <name>G4N620_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716915.1">
        <property type="nucleotide sequence ID" value="XM_003716867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N620"/>
    <dbReference type="GeneID" id="12985481"/>
    <dbReference type="KEGG" id="mgr:MGG_17150"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17150"/>
    <dbReference type="HOGENOM" id="CLU_1027021_0_0_1"/>
    <dbReference type="InParanoid" id="G4N620"/>
    <dbReference type="OrthoDB" id="10631105at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="271" mass="30287" checksum="F9C11D7EAC7028CC" modified="2011-12-14" version="1">MAIRVCWIGHRVSRSLKIVGDSRTDTSSPCSLMPEIPKNCVARQPRPGLDTIEGWGGVHPIIVVTARDWARMRGRPLHVWGLRMWRYRNGFRSNDGKDWGGCVSGFQRIVVHGMDSGMRNFTSRLTTIHFPDSLAMARMGPIEVHVHQRRVSNCTGWWHPSKQLGRQSLERPSRLCACANEKGDGGRALGGWRESKSGLRIAIGTMLWDGGVFFLSQSPRGRATASLWHQGRSTNRSSCLIHKATRQPDLTTHQMPHSTVSIPERGRAGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N702</accession>
    <name>G4N702_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vps72/YL1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_12827</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS72/YL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717085.1">
        <property type="nucleotide sequence ID" value="XM_003717037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N702"/>
    <dbReference type="SMR" id="G4N702"/>
    <dbReference type="STRING" id="242507.G4N702"/>
    <dbReference type="GeneID" id="5050197"/>
    <dbReference type="KEGG" id="mgr:MGG_12827"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12827"/>
    <dbReference type="eggNOG" id="ENOG502S4HA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008699_1_0_1"/>
    <dbReference type="InParanoid" id="G4N702"/>
    <dbReference type="OMA" id="PVISYWS"/>
    <dbReference type="OrthoDB" id="3942062at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046757">
        <property type="entry name" value="YL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05764">
        <property type="entry name" value="YL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="3">
        <location>
            <begin position="605"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="335"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="688"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="537"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="721"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="740"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="796"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="814"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="836"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="862" mass="91878" checksum="A2F3B4F625A369A0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N740</accession>
    <name>G4N740_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glucose transporter rco-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_03620</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716272.1">
        <property type="nucleotide sequence ID" value="XM_003716224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N740"/>
    <dbReference type="SMR" id="G4N740"/>
    <dbReference type="FunCoup" id="G4N740">
        <property type="interactions" value="183"/>
    </dbReference>
    <dbReference type="TCDB" id="2.A.1.1.117">
        <property type="family name" value="the major facilitator superfamily (mfs)"/>
    </dbReference>
    <dbReference type="GeneID" id="2676756"/>
    <dbReference type="KEGG" id="mgr:MGG_03620"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03620"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="InParanoid" id="G4N740"/>
    <dbReference type="OMA" id="RRTFTGC"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="PHI-base" id="PHI:4024"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF40">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465876" evidence="10">
        <location>
            <begin position="33"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="20"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="502"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="511"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="527"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA49953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="547" mass="59623" checksum="02E045F07EF51739" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7L2</accession>
    <name>G4N7L2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWR1-complex protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_06385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SWC5 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA50869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003717140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7L2"/>
    <dbReference type="FunCoup" id="G4N7L2">
        <property type="interactions" value="436"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7L2"/>
    <dbReference type="GeneID" id="2684540"/>
    <dbReference type="KEGG" id="mgr:MGG_06385"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06385"/>
    <dbReference type="eggNOG" id="KOG4776">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062474_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7L2"/>
    <dbReference type="OMA" id="LDWAAYV"/>
    <dbReference type="OrthoDB" id="445677at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011421">
        <property type="entry name" value="BCNT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027124">
        <property type="entry name" value="Swc5/CFDP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407:SF1">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07572">
        <property type="entry name" value="BCNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51279">
        <property type="entry name" value="BCNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCNT-C" evidence="4">
        <location>
            <begin position="267"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
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        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA50869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="344" mass="37432" checksum="E83FC8007196F41C" modified="2011-12-14" version="1">MATTATIPPDPEVEEEYASSEDSDFAPEDAGARESSPDDSDDEDVPPDATSATAPKRKRIANNEEPQNVGFENSGDEAIIEKAKTKRQKKARKANQDGDDGGDGGLIKTRSQRAQEKAERKAIAVSGPVTVDIDALWAQMNNPNPAVQASHQADVATKVEAVAAAVVNAGDTDKTTTTESTTQVPQTIKIKRTYNFAGKVHTEEKLVSRDSAEAKLYLESIGEGAIPEAAHEDGDQPRRRPKKAFRSAFEPISDQLASRRDLNLGIAARMEARDLAKDANAKKLTTVEKSRMDWAGYVDKEGIQDELKLAGKSKHSYAERQGFLARSEARREDDARKARMATRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7S8</accession>
    <name>G4N7S8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_06373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717201.1">
        <property type="nucleotide sequence ID" value="XM_003717153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7S8"/>
    <dbReference type="SMR" id="G4N7S8"/>
    <dbReference type="GeneID" id="2684528"/>
    <dbReference type="KEGG" id="mgr:MGG_06373"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06373"/>
    <dbReference type="eggNOG" id="ENOG502QTX9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_1_1_1"/>
    <dbReference type="InParanoid" id="G4N7S8"/>
    <dbReference type="OMA" id="LMTRPHR"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051704">
        <property type="entry name" value="FAD_aromatic-hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865:SF2">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46865">
        <property type="entry name" value="OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="46408" checksum="0DB2153C8AB9F8F3" modified="2011-12-14" version="1">MSSPRILISGSGIAGSSFAYWMLRAFPTAAITMVERCPTFRLTGSSVDLRSSAIDICKRMNMLDTVKAHTTTERGIRFVNSDGSTVATLGASGRSDVQGITSEYEIFRSDLARIILEPSRDKINILFDDYVDKYETEKDGVKVTFAKSKRVDKYDLLVAADGVGSRIRGQMLNSNPREQVHDEGVHVAYFTQKSDLLNGSKFAEGYSAPGGRVIMVRPDPHPEGRSKVIIMNVTTKNDLAAKKRLNDAVDAGNEAYMALLEETFADVGHRSAEVLKGMRESDDFYCSLFAQVRSPKLVDQSGRVVLLGDAGYATPGIGTSLAMIGAYVLAGELLSSTSGTSIKIPAATSKYQDLMVPFVKSHQGDDNAMQILNPQTSWGIMLRDVALRVVTGLWLDRLAMIAAAKLGFTDKMLDMPEYAWPKWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4N817</accession>
    <name>G4N817_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_03485</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716438.1">
        <property type="nucleotide sequence ID" value="XM_003716390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N817"/>
    <dbReference type="SMR" id="G4N817"/>
    <dbReference type="FunCoup" id="G4N817">
        <property type="interactions" value="802"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N817"/>
    <dbReference type="GeneID" id="2676442"/>
    <dbReference type="KEGG" id="mgr:MGG_03485"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03485"/>
    <dbReference type="eggNOG" id="KOG0323">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007683_0_2_1"/>
    <dbReference type="InParanoid" id="G4N817"/>
    <dbReference type="OMA" id="DQTVIHC"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="166"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="514"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="615"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="627"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="665"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="709"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="820"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA50119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="866" mass="96256" checksum="5E61F6A4D755E501" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N824</accession>
    <name>G4N824_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716445.1">
        <property type="nucleotide sequence ID" value="XM_003716397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N824"/>
    <dbReference type="STRING" id="242507.G4N824"/>
    <dbReference type="GeneID" id="2676829"/>
    <dbReference type="KEGG" id="mgr:MGG_03480"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03480"/>
    <dbReference type="eggNOG" id="KOG1039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018150_1_1_1"/>
    <dbReference type="InParanoid" id="G4N824"/>
    <dbReference type="OMA" id="YDMIPTI"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="475" mass="50198" checksum="D172B127D7CFB0AF" modified="2011-12-14" version="1">MRNPDAYGGPNAYLAPEDQYAAHQLGRQPSMENGVPTIDTTYSSNPASMYGSPRDDELNRFGMGLSPVAFKGLSVLDAPLPASFDSNGISHAARYGPWPSSMPSKFGLESASASLSTPKDPRTSETLKLLHTSAFGSSDHLSPASHESAVAIGNSPPVNGDEEYFGKRTMHSSSRFAKPRMLSASAPKGDRDDWDPGFMFFEEDYIPSTLANDVLTPQEKARRGSVRLTDDPTTSSGVIGNGSDASSLPKFGSLGASPSRWGPLFQRYRSEEDSDPNHHGHRMIPGKSMKNVASVFGHVGSPLRNSSLAIDAEMDSLANGNGSPSNRSRSESLTALTQQLQTTKIGDINNSSSPRLHPNSARGINGTGLGSSSLLGSRDRDFDPRGSTQRNVSSGSISSSGRFTTPIDEEDSAFVFSMEEEDDAAAAQNHMRTKKRASGGLGATGWSYAGVAAGNAKNGLSNGSKGRDGLGVSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8B7</accession>
    <name>G4N8B7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Globin-sensor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716483.1">
        <property type="nucleotide sequence ID" value="XM_003716435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8B7"/>
    <dbReference type="SMR" id="G4N8B7"/>
    <dbReference type="GeneID" id="2676478"/>
    <dbReference type="KEGG" id="mgr:MGG_03446"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03446"/>
    <dbReference type="eggNOG" id="ENOG502S0AP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063074_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8B7"/>
    <dbReference type="OMA" id="YIHLGAC"/>
    <dbReference type="OrthoDB" id="10027058at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071:SF1">
        <property type="entry name" value="GLOBIN-SENSOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071">
        <property type="entry name" value="PROTOGLOBIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin-sensor" evidence="2">
        <location>
            <begin position="24"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="327" mass="36596" checksum="26AEAB9BFC64F700" modified="2011-12-14" version="1">MGFTMASDRLRMHVERRDLYTNLEARIHYLHSFLDFSSRDIEALVSGAKYVRALIPAVVNIVYKKLLRYDITARAFTTRSTSFEGPMDECPDEDSPQIQHRKVFLRAYLSKLCSDPSQMEFWEYLDKVGMMHVGLGRAHPLHVEYVHLGVCLAFIQDIMSEAILSHPRMAMQNKIALVKALGKVIWIQNDLMAKWQVRDGAEFHTDDGSEEEIVIEKEGYLHGKKILDEDDDVPEAVSPASSTSSQHTLTPPRSLLSPLSPTTCMPRRSTGSEGAGVCPFSGRQANDPSTPERRKPDIKIEVSEPVTFAGSMQSLSGVALSGRTESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9K3</accession>
    <name>G4N9K3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717510.1">
        <property type="nucleotide sequence ID" value="XM_003717462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9K3"/>
    <dbReference type="GeneID" id="2681021"/>
    <dbReference type="KEGG" id="mgr:MGG_09998"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09998"/>
    <dbReference type="HOGENOM" id="CLU_2440988_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9K3"/>
    <dbReference type="OrthoDB" id="5168947at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466322" evidence="2">
        <location>
            <begin position="18"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="93" mass="9608" checksum="5661B9B2FF2B4A38" modified="2011-12-14" version="1">MKASSILALIFVGVAVAAPGTPVQGAVLEGRQTKPTPPKNTPKPSSPPTTCTPGKYRCSGSDIQVCNSSKQWVLSAKCSPKKCSEQNGGAYCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAB4</accession>
    <name>G4NAB4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Polyamine transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03205</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716778.1">
        <property type="nucleotide sequence ID" value="XM_003716730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAB4"/>
    <dbReference type="FunCoup" id="G4NAB4">
        <property type="interactions" value="68"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAB4"/>
    <dbReference type="GeneID" id="2676509"/>
    <dbReference type="KEGG" id="mgr:MGG_03205"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03205"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_11_4_1"/>
    <dbReference type="InParanoid" id="G4NAB4"/>
    <dbReference type="OMA" id="AQNWPLR"/>
    <dbReference type="OrthoDB" id="9986881at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF31">
        <property type="entry name" value="POLYAMINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="508"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="537"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="170"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="613"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="644"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="660" mass="72132" checksum="B4F337444343379A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAG9</accession>
    <name>G4NAG9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Arabinogalactan endo-beta-1,4-galactanase</fullName>
            <ecNumber evidence="3 7">3.2.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_09726</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>The enzyme specifically hydrolyzes (1-&gt;4)-beta-D-galactosidic linkages in type I arabinogalactans.</text>
            <dbReference type="EC" id="3.2.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 53 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.89" evidence="3 7"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717626.1">
        <property type="nucleotide sequence ID" value="XM_003717578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAG9"/>
    <dbReference type="SMR" id="G4NAG9"/>
    <dbReference type="STRING" id="242507.G4NAG9"/>
    <dbReference type="CAZy" id="GH53">
        <property type="family name" value="Glycoside Hydrolase Family 53"/>
    </dbReference>
    <dbReference type="GeneID" id="2680680"/>
    <dbReference type="KEGG" id="mgr:MGG_09726"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09726"/>
    <dbReference type="eggNOG" id="ENOG502QU6R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011259_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAG9"/>
    <dbReference type="OMA" id="KYIHDEW"/>
    <dbReference type="OrthoDB" id="110914at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031218">
        <property type="term" value="F:arabinogalactan endo-1,4-beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030247">
        <property type="term" value="F:polysaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000077">
        <property type="entry name" value="Arabinogalactan endo-beta-1,4-galactanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011683">
        <property type="entry name" value="Glyco_hydro_53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34983">
        <property type="entry name" value="ARABINOGALACTAN ENDO-BETA-1,4-GALACTANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34983:SF1">
        <property type="entry name" value="ARABINOGALACTAN ENDO-BETA-1,4-GALACTANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07745">
        <property type="entry name" value="Glyco_hydro_53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005132198" description="Arabinogalactan endo-beta-1,4-galactanase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00068680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA51307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="351" mass="38953" checksum="03672B53A2F6FA17" modified="2011-12-14" version="1">MRFPAQTLGFLLSFLPTVAVALTHKGVDWSSLLVSESAGRSFQDVNGQTRPLEQILASNGVNTVRQRVWVGAGSTYNLDYNLRLARRAKAAGMNVYLTLHFSDSWADPGQQTIPAGWPRDIDNLSWRLYNYTMEVGNAFAGAGVTPSIVSIGNEIRAGLLWPTGDYNNFYNMARLLHSASSGIRDSRLGRAPKIMVHLDNGWNWDTQKWFYESLLKQGPFVPGDFDQMGVSFYPFYGPDATFANLKTSLTNMANTWGKEIIVAETNWPTSCPSPQYQFPADVRSIPFSADGQTQFFRRVAKIVSGVRNGNGLFVWEPAWIDNQALGSSCQSNTMFAWPGKALSSLSVFKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAQ9</accession>
    <name>G4NAQ9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aflatoxin B1 aldehyde reductase member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08519</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716021.1">
        <property type="nucleotide sequence ID" value="XM_003715973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAQ9"/>
    <dbReference type="SMR" id="G4NAQ9"/>
    <dbReference type="GeneID" id="2678797"/>
    <dbReference type="KEGG" id="mgr:MGG_08519"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08519"/>
    <dbReference type="eggNOG" id="ENOG502R41Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_1_1_1"/>
    <dbReference type="InParanoid" id="G4NAQ9"/>
    <dbReference type="OMA" id="CREKNYV"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="333" mass="36326" checksum="133CF59300CD2EC7" modified="2011-12-14" version="1">MATNGISIVFGGGSFWRGTVDEISSWLDVLEKAGIKKIDTAEVYGQSQYLLGKAGAPSRFIIDSKAVSGMGPNPSTAEVILEAGRKSLELLGTDSLDVYYLHSPDTRVPWKDTLTGLNELYKQGAFKRLGLSNFTAKQIDEFVQVAKENNFVVPSVYQGHYSPVARKIEDDVIPTLRRHNMSLYSYSPSAGGFLTRPKEALLEGRLGKKDEFGAVSNALYNKPSFIAALDTWARIARDEGVELGELAYRWVVYHSQLRAASGDAIIAGASKQHQLVEAVEWMKKGPLSDAAAQRVDAMWDDVRAEAATHNMPDGMKPSEIVPELAGKSAAESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAY1</accession>
    <name>G4NAY1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Endoplasmic oxidoreductin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MGG_00683</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718326.1">
        <property type="nucleotide sequence ID" value="XM_003718278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAY1"/>
    <dbReference type="SMR" id="G4NAY1"/>
    <dbReference type="FunCoup" id="G4NAY1">
        <property type="interactions" value="749"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAY1"/>
    <dbReference type="GeneID" id="2675010"/>
    <dbReference type="KEGG" id="mgr:MGG_00683"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00683"/>
    <dbReference type="eggNOG" id="KOG2608">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023061_1_0_1"/>
    <dbReference type="InParanoid" id="G4NAY1"/>
    <dbReference type="OMA" id="CYKDRLH"/>
    <dbReference type="OrthoDB" id="269384at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017205">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 17" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 20" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466281" evidence="20">
        <location>
            <begin position="23"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB96</accession>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
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                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBS7</accession>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718569.1">
        <property type="nucleotide sequence ID" value="XM_003718521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBS7"/>
    <dbReference type="GeneID" id="12984123"/>
    <dbReference type="KEGG" id="mgr:MGG_17447"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17447"/>
    <dbReference type="HOGENOM" id="CLU_2812902_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBS7"/>
    <dbReference type="OrthoDB" id="10554383at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="67" mass="7372" checksum="E18CC9D08A1E1CDA" modified="2011-12-14" version="1">MARIVVIRDRGGERRNSGRSLGNRGSFYLAPVRKRGTSPSFGQVATCVRNIPGWLWINGQPAEAMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCM4</accession>
    <name>G4NCM4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_14692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718702.1">
        <property type="nucleotide sequence ID" value="XM_003718654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCM4"/>
    <dbReference type="SMR" id="G4NCM4"/>
    <dbReference type="GeneID" id="5049205"/>
    <dbReference type="KEGG" id="mgr:MGG_14692"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14692"/>
    <dbReference type="eggNOG" id="ENOG502SPMP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039960_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCM4"/>
    <dbReference type="OMA" id="IETCEHE"/>
    <dbReference type="OrthoDB" id="21678at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01823">
        <property type="entry name" value="SEST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037460">
        <property type="entry name" value="SEST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981">
        <property type="entry name" value="LIPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37981:SF1">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466812" evidence="2">
        <location>
            <begin position="24"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="435" mass="47747" checksum="16C0DD808755FCF6" modified="2011-12-14" version="1">MYLAKQPFLATWLAQFFVTLASSSAPSPPWKSPTWSDDGESAQKPIDSPLDVASGPGIGYIALGDSYGAGIGTEYDGDEDKCRLGNHAYTSLIYRDLVKAWEEGGGVDGTPRPVFQWRSCTGATSSDLLGQGGQIASLNGSLPASFATLSIGGNDLGFFDVMNSCIFRFYGFYSGTCAAAIRRATNLLDSPAFELSLEMALLSLLDAARWEQHPRFAIVVTGYARFFDARTSACDDRSLGVWLGGPKLSARLRARLNGLVDDVNARLRSTVRAVNSRFASRRQRVLFVDYDEQFEGHRFCEPGVLEPDYQREDTWFFLVGGKDNGSGGEGAVKEEPRRVELPVVDPDTCLGPARDSGDWGALAVCYMAMAKQRDPSLRLARPVVEDGDDGASTQYTSIYYAKTFHPRSLGHEAIRDAVYREWEKVFDEDLVHSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCP9</accession>
    <name>G4NCP9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSm2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_00355</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718727.1">
        <property type="nucleotide sequence ID" value="XM_003718679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCP9"/>
    <dbReference type="SMR" id="G4NCP9"/>
    <dbReference type="FunCoup" id="G4NCP9">
        <property type="interactions" value="1025"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NCP9"/>
    <dbReference type="GeneID" id="2674959"/>
    <dbReference type="KEGG" id="mgr:MGG_00355"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00355"/>
    <dbReference type="eggNOG" id="KOG3448">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130474_3_0_1"/>
    <dbReference type="InParanoid" id="G4NCP9"/>
    <dbReference type="OMA" id="DNISCTD"/>
    <dbReference type="OrthoDB" id="10256176at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01725">
        <property type="entry name" value="LSm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000009">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016654">
        <property type="entry name" value="U6_snRNA_Lsm2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13829">
        <property type="entry name" value="SNRNP CORE PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13829:SF2">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016394">
        <property type="entry name" value="U6_snRNA_Lsm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="2"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA49143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="97" mass="11016" checksum="6AB7055D863E035D" modified="2011-12-14" version="1">MLFFSFFKTLIDVEITVELKNSIQIRGTLKSVDQYLNLKLDDISVVEDIKYPHLSAVKNVFIRGSVVRYIHLPASHVDVPLLEDATRREAASTAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND73</accession>
    <name>G4ND73_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_00296</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718795.1">
        <property type="nucleotide sequence ID" value="XM_003718747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND73"/>
    <dbReference type="SMR" id="G4ND73"/>
    <dbReference type="CAZy" id="GH92">
        <property type="family name" value="Glycoside Hydrolase Family 92"/>
    </dbReference>
    <dbReference type="GeneID" id="2674447"/>
    <dbReference type="KEGG" id="mgr:MGG_00296"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00296"/>
    <dbReference type="eggNOG" id="ENOG502QR5Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003690_4_1_1"/>
    <dbReference type="InParanoid" id="G4ND73"/>
    <dbReference type="OMA" id="TMVNPQN"/>
    <dbReference type="OrthoDB" id="449263at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1610.10:FF:000002">
        <property type="entry name" value="Alpha-1,2-mannosidase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.10:FF:000010">
        <property type="entry name" value="Alpha-1,2-mannosidase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2080.10:FF:000001">
        <property type="entry name" value="Alpha-1,2-mannosidase subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.60:FF:000002">
        <property type="entry name" value="Glycosyl hydrolase family 92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.60">
        <property type="entry name" value="alpha-1,2-mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1610.10">
        <property type="entry name" value="alpha-1,2-mannosidases domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2080.10">
        <property type="entry name" value="GH92 mannosidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="GH92_a_mannosidase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF25">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466831" evidence="2">
        <location>
            <begin position="24"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92 N-terminal" evidence="4">
        <location>
            <begin position="30"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 92" evidence="3">
        <location>
            <begin position="288"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="789"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA49211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="827" mass="90643" checksum="4B058015BC1169EF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDB6</accession>
    <name>G4NDB6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A diphosphatase SCS3</fullName>
            <ecNumber evidence="8">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">FIT family protein SCS3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SCS3</name>
        <name evidence="8" type="synonym">FIT2B</name>
        <name evidence="11" type="ORF">MGG_00264</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65568"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57368"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:156554"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(9Z)-octadecenoyl-CoA + H2O = S-(9Z-octadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:65564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:156553"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:50044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:132023"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>hexadecanoyl-CoA + H2O = S-hexadecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:50032"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:132018"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718838.1">
        <property type="nucleotide sequence ID" value="XM_003718790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDB6"/>
    <dbReference type="FunCoup" id="G4NDB6">
        <property type="interactions" value="76"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NDB6"/>
    <dbReference type="GeneID" id="2674632"/>
    <dbReference type="KEGG" id="mgr:MGG_00264"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00264"/>
    <dbReference type="eggNOG" id="KOG3750">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048143_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDB6"/>
    <dbReference type="OMA" id="CERIHAS"/>
    <dbReference type="OrthoDB" id="5579088at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03231">
        <property type="entry name" value="SCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019388">
        <property type="entry name" value="FIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046400">
        <property type="entry name" value="SCS3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23129:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE FITM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10261">
        <property type="entry name" value="FIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA49254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="352" mass="38023" checksum="B057F4599A734A0C" modified="2011-12-14" version="1">MTDSPISRKRPNSTVSTPISPSADSLHSPSSSRSSPSSSSSSRHPPYLPTRLETYVLALYPTLLVFGSAFALLSPAVRAAKYDPYAQAHVQDSTAPSYFARKDNVFNVLFVKRGWAWITGAFLTFVATHQGITPTAAKARAAVRWALVTGWWVLVTQWCFGPPLIDRGFRYTGGKCEAAQAAVAEDGVAGSAAKDVFSAAACRAAGGRWSGGHDISGHVFLLVLGSFFLVQEVGWVVIRWRARGWELRGKDTRTVVMVDGAVKSADVEAEDLWEKSLLGAQEGWLDVLGLGGKVALAVVGLSLWMLLMTAIFFHTWFEKLTGLLVAFTGLYGVYFVPRLIPGLRALVGMPGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDD0</accession>
    <name>G4NDD0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718003.1">
        <property type="nucleotide sequence ID" value="XM_003717955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDD0"/>
    <dbReference type="GeneID" id="12983996"/>
    <dbReference type="KEGG" id="mgr:MGG_17335"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17335"/>
    <dbReference type="HOGENOM" id="CLU_1669732_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDD0"/>
    <dbReference type="OMA" id="DHAHRHQ"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466475" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17203" checksum="76522FF0429E2D80" modified="2011-12-14" version="1">MLPCLPLRLLVLMLLVKVHATRAVKVLLHGRRLLLKYRRHAAAAAPPPHRKLQLGLDPSVHSDHAHRHQRCLARRRRGCRNRDGAAVGAGVADQARPAHDAVGAAVVVFVVHARLEAPLLIRGASLFVIICLDPVAQIKGLSSPSRLPGSQNLRSGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEI0</accession>
    <name>G4NEI0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidyl synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719041.1">
        <property type="nucleotide sequence ID" value="XM_003718993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEI0"/>
    <dbReference type="SMR" id="G4NEI0"/>
    <dbReference type="FunCoup" id="G4NEI0">
        <property type="interactions" value="255"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NEI0"/>
    <dbReference type="GeneID" id="2674773"/>
    <dbReference type="KEGG" id="mgr:MGG_00099"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00099"/>
    <dbReference type="eggNOG" id="KOG1618">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030880_3_0_1"/>
    <dbReference type="InParanoid" id="G4NEI0"/>
    <dbReference type="OMA" id="SWMETIH"/>
    <dbReference type="OrthoDB" id="10251048at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000069">
        <property type="entry name" value="HAD-superfamily subfamily IIA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006353">
        <property type="entry name" value="HAD-SF_hydro_IIA_CECR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01456">
        <property type="entry name" value="CECR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF51">
        <property type="entry name" value="HYPOTHETICAL HAD-SUPERFAMILY HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="58729" checksum="72AC6509771FFEF9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFG1</accession>
    <name>G4NFG1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719556.1">
        <property type="nucleotide sequence ID" value="XM_003719508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFG1"/>
    <dbReference type="GeneID" id="12986008"/>
    <dbReference type="KEGG" id="mgr:MGG_17663"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17663"/>
    <dbReference type="HOGENOM" id="CLU_1185208_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFG1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="234" mass="25872" checksum="F5BF8CF8B30A79BA" modified="2011-12-14" version="1">MPTTSSAPVYVPSASRKLRKAGDTPYMSIHSLTRRRFPVRVRSMGRLSHTIPPRPTVHGVYQGCEPRPCPRFLLPVTQSRLQQWADHVLLSGPFGDCRAGTVLPVHVQLTNPRNGTTSSLQAIPEAAVKSPTLRAGQMSIFKPYPRFREPFGFKARNLIRTSEPLLVTLLLSGLNPQRGLSSHDNEPAAEYHNNIASSDVGLDDCNQDASACKDNSIKRSNFDLETDSIHKSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFQ5</accession>
    <name>G4NFQ5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719229.1">
        <property type="nucleotide sequence ID" value="XM_003719181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFQ5"/>
    <dbReference type="GeneID" id="12985209"/>
    <dbReference type="KEGG" id="mgr:MGG_17575"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17575"/>
    <dbReference type="HOGENOM" id="CLU_2904654_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFQ5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="62" mass="6986" checksum="218AEC422B667C1F" modified="2011-12-14" version="1">MEGNDGSRRKFFEVVYQWLVYYYTQGSENALGCIVTEMRSHSGGALAVKVSPSIKKKRLGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHD6</accession>
    <name>G4NHD6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleolar protein 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Pumilio domain-containing protein NOP9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03872</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720013.1">
        <property type="nucleotide sequence ID" value="XM_003719965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHD6"/>
    <dbReference type="SMR" id="G4NHD6"/>
    <dbReference type="FunCoup" id="G4NHD6">
        <property type="interactions" value="896"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NHD6"/>
    <dbReference type="GeneID" id="2677142"/>
    <dbReference type="KEGG" id="mgr:MGG_03872"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03872"/>
    <dbReference type="eggNOG" id="KOG2188">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008720_1_1_1"/>
    <dbReference type="InParanoid" id="G4NHD6"/>
    <dbReference type="OMA" id="WIKDMVA"/>
    <dbReference type="OrthoDB" id="392571at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040000">
        <property type="entry name" value="NOP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="331"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="520"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="731"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="520"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="553"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="743"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="775"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="785" mass="87488" checksum="D28E681D2DC872BD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHE8</accession>
    <name>G4NHE8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_03866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720025.1">
        <property type="nucleotide sequence ID" value="XM_003719977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHE8"/>
    <dbReference type="GeneID" id="2677267"/>
    <dbReference type="KEGG" id="mgr:MGG_03866"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03866"/>
    <dbReference type="HOGENOM" id="CLU_1289156_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHE8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="214" mass="24408" checksum="B386F4B1D3AADEEB" modified="2011-12-14" version="1">MGGESNPPPMFSLILQLWHGPMTYHTYYYSKENHLGHLNLKFRVGRLLGGKQLYITEKARHLGDTQLWKQEFAYLLPRATSPKGVSLYDQTVSLNHQSMGVLEAAGRGPETGLVGTKVGSVLHYVRSISPFQYTHPKDCVVIKCGYFVGFSYRNTWQTPVRRSKIGSVWGLLRPKNFRPGEMRLQGPRWRLKIIHASELLPMLPCSRTRSHDPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHH2</accession>
    <name>G4NHH2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03841</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720049.1">
        <property type="nucleotide sequence ID" value="XM_003720001.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NHH2"/>
    <dbReference type="FunCoup" id="G4NHH2">
        <property type="interactions" value="1197"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NHH2"/>
    <dbReference type="GeneID" id="2677343"/>
    <dbReference type="KEGG" id="mgr:MGG_03841"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03841"/>
    <dbReference type="eggNOG" id="KOG0168">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0170">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000366_0_1_1"/>
    <dbReference type="InParanoid" id="G4NHH2"/>
    <dbReference type="OMA" id="AEPLSQF"/>
    <dbReference type="OrthoDB" id="423283at2759"/>
    <dbReference type="PHI-base" id="PHI:11101"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="HECT_dom"/>
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        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
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        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25579">
        <property type="entry name" value="TPR_TRIP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="1567"/>
            <end position="1923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="579"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="725"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1113"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1242"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1363"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1593"/>
            <end position="1619"/>
        </location>
    </feature>
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        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
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        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
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        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
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        <location>
            <begin position="579"/>
            <end position="596"/>
        </location>
    </feature>
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            <begin position="725"/>
            <end position="737"/>
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    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="1255"/>
            <end position="1273"/>
        </location>
    </feature>
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        <location>
            <position position="1890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1923" mass="209305" checksum="7501B58989AFF896" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHI4</accession>
    <name>G4NHI4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_03831</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720061.1">
        <property type="nucleotide sequence ID" value="XM_003720013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHI4"/>
    <dbReference type="SMR" id="G4NHI4"/>
    <dbReference type="STRING" id="242507.G4NHI4"/>
    <dbReference type="GeneID" id="2677181"/>
    <dbReference type="KEGG" id="mgr:MGG_03831"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03831"/>
    <dbReference type="eggNOG" id="ENOG502SJ01">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002220_3_1_1"/>
    <dbReference type="InParanoid" id="G4NHI4"/>
    <dbReference type="OMA" id="DYVYLAH"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="26"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="563"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA47694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="596" mass="66673" checksum="580B8A1B759E763E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI02</accession>
    <name>G4NI02_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">NIMA-interacting protein TinC</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_09383</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720229.1">
        <property type="nucleotide sequence ID" value="XM_003720181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI02"/>
    <dbReference type="STRING" id="242507.G4NI02"/>
    <dbReference type="GeneID" id="2680382"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09383"/>
    <dbReference type="eggNOG" id="ENOG502QRXF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4NI02"/>
    <dbReference type="OrthoDB" id="2506204at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010816">
        <property type="entry name" value="Het-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052577">
        <property type="entry name" value="VWA7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905">
        <property type="entry name" value="NG37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905:SF11">
        <property type="entry name" value="TINC (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07217">
        <property type="entry name" value="Het-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466670" evidence="2">
        <location>
            <begin position="26"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="725"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="749"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="854"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="868"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="916" mass="100639" checksum="9B58A64BB8DF898B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIQ9</accession>
    <name>G4NIQ9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17681</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719681.1">
        <property type="nucleotide sequence ID" value="XM_003719633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIQ9"/>
    <dbReference type="GeneID" id="12986148"/>
    <dbReference type="KEGG" id="mgr:MGG_17681"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17681"/>
    <dbReference type="HOGENOM" id="CLU_2688301_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIQ9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466690" evidence="1">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="74" mass="7919" checksum="2B109109847C010F" modified="2011-12-14" version="1">MWIFTLELEGIVAATSLAASERADDASGIGAGGAKPDMLRLGGHPARWQSGRAAKVHNVAKYRFVAVKYSGWMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL01</accession>
    <name>G4NL01_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_09645</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721439.1">
        <property type="nucleotide sequence ID" value="XM_003721391.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NL01"/>
    <dbReference type="STRING" id="242507.G4NL01"/>
    <dbReference type="GeneID" id="2680581"/>
    <dbReference type="KEGG" id="mgr:MGG_09645"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09645"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_1_1"/>
    <dbReference type="InParanoid" id="G4NL01"/>
    <dbReference type="OMA" id="WHYDKEY"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF49">
        <property type="entry name" value="SYNTHASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="50"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="11">
        <location>
            <begin position="938"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2028"/>
            <end position="2107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="7">
        <location>
            <begin position="938"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="7">
        <location>
            <begin position="1088"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1450"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="7">
        <location>
            <position position="970"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="7">
        <location>
            <position position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA46696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="2126" mass="227641" checksum="66AB71237704F583" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL86</accession>
    <name>G4NL86_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09614</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721474.1">
        <property type="nucleotide sequence ID" value="XM_003721426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL86"/>
    <dbReference type="SMR" id="G4NL86"/>
    <dbReference type="STRING" id="242507.G4NL86"/>
    <dbReference type="GeneID" id="2680619"/>
    <dbReference type="KEGG" id="mgr:MGG_09614"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09614"/>
    <dbReference type="eggNOG" id="ENOG502S31Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035914_2_1_1"/>
    <dbReference type="InParanoid" id="G4NL86"/>
    <dbReference type="OMA" id="NCNQEYV"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF116">
        <property type="entry name" value="TYROSINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466648" description="Tyrosinase copper-binding domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="3">
        <location>
            <begin position="141"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="387" mass="43501" checksum="712BE8580873B8E6" modified="2011-12-14" version="1">MRFTLSLILSAALASTAAAMPQAATKEVRSEPKLIDLAPFKASGTGYKPKKILTEDEARALTAKNLEAAKAPKSAIERRNCKRNEEEYHKMKAKSTCKNPEVRVEWRNFPHEYRLKWVKAARCLYDLPPRMGYPGSKNLAEDFAYIHQQLMENIHAVGHFNVWHRLFLWHYQETLRDQCGYPRDLPLPWWDETKDSGNFANSPIFTPEYYGSAPKVVVKDGKEFATCIEDGAFANITVSIGPAKSVTTPHCLSRALNETKTALTGKAYCDLGNSYSDFWKMAVTQEEGMHANGHEGVGSVMGDMWASPADAIFYMHHTFTDRYFTAWQNADPVRRTYAIGGPNATVGPVSPSTNDSPIRFLGLFPDTTIREIQDAQGGSPFCYKYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH78</accession>
    <name>G5EH78_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15793</name>
        <name evidence="3" type="ORF">MGG_16553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711121.1">
        <property type="nucleotide sequence ID" value="XM_003711073.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714929.1">
        <property type="nucleotide sequence ID" value="XM_003714881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH78"/>
    <dbReference type="GeneID" id="12985458"/>
    <dbReference type="GeneID" id="12986920"/>
    <dbReference type="KEGG" id="mgr:MGG_15793"/>
    <dbReference type="KEGG" id="mgr:MGG_16553"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15793"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16553"/>
    <dbReference type="eggNOG" id="ENOG502SV11">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149544_0_0_1"/>
    <dbReference type="OrthoDB" id="3598923at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007661302" evidence="1">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="116" mass="12468" checksum="405F4EF829DC1019" modified="2011-12-14" version="1">MKASNTLVALCVATAATEAYVITIYSVENCQGTGKRINVYDNSCSVPNFPGGAQSVRVEKYGAGAQKARFYRNNACVGNPHRGPWDAGKSDNLWEAGKCIEMGKGYTVQSFTSYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH85</accession>
    <name>G5EH85_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Epoxide hydrolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGCH7_ch7g872</name>
        <name evidence="7" type="ORF">MGG_03070</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15</strain>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">70-15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720605.1">
        <property type="nucleotide sequence ID" value="XM_003720557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH85"/>
    <dbReference type="SMR" id="G5EH85"/>
    <dbReference type="STRING" id="242507.G5EH85"/>
    <dbReference type="ESTHER" id="maggr-q2kf14">
        <property type="family name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="GeneID" id="2682623"/>
    <dbReference type="KEGG" id="mgr:MGG_03070"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03070"/>
    <dbReference type="eggNOG" id="KOG2565">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019414_0_2_1"/>
    <dbReference type="OMA" id="RGYQRIQ"/>
    <dbReference type="OrthoDB" id="7130006at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EAQ71465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA45862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="410" mass="46519" checksum="4268707F502ED512" modified="2011-12-14" version="1">MTDEIRPFKIKISDEELDNLNKRLDLARIPDNIDDVEWDEENGVTVDFIRRTVSHWRNGYSWREHEAKLNEMPQFKTTIKLSATNKAGQTFDPVEVHFAHVKATQKPASGGPAIPLIFIHGWPGNFAEVQKALPALNAAGFDVVAPSLMGYGWSSLPRQAGFNMFHHADVFHHLMVRLGYDRYVVQGGDWGAIVSRALLMQHPEHAVALHVNMPYVTSSELSPEESANLTEAELAAVERFQWYKDYEQAYTAVQATKPRTFGFALHDSPVAMLSWMADKMNLWSDLENLPGGGYTTDEYITWTLLHYFPGPTTAIQMYRANFGEQMKQHVAEPAAKLLARNRVDNPVGVSHFPKEIAVSPRVLFEKENNVVFWREQQKGGHFAAHEQPEVFAKDVIEFLTGQWKSFQANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHG3</accession>
    <name>G5EHG3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine cleavage system P protein</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGCH7_ch7g895</name>
        <name evidence="11" type="ORF">MGG_15038</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15</strain>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GcvP family.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720581.1">
        <property type="nucleotide sequence ID" value="XM_003720533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHG3"/>
    <dbReference type="SMR" id="G5EHG3"/>
    <dbReference type="FunCoup" id="G5EHG3">
        <property type="interactions" value="689"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EHG3"/>
    <dbReference type="GeneID" id="12984732"/>
    <dbReference type="KEGG" id="mgr:MGG_15038"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15038"/>
    <dbReference type="eggNOG" id="KOG2040">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_3_2_1"/>
    <dbReference type="OMA" id="RNLICTC"/>
    <dbReference type="OrthoDB" id="6537869at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016594">
        <property type="term" value="F:glycine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000005">
        <property type="entry name" value="Glycine dehydrogenase (decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000007">
        <property type="entry name" value="Glycine dehydrogenase (decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000224">
        <property type="entry name" value="Probable glycine dehydrogenase (decarboxylating) subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049316">
        <property type="entry name" value="GDC-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049315">
        <property type="entry name" value="GDC-P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003346">
        <property type="entry name" value="PRK04366.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773:SF1">
        <property type="entry name" value="GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="GLYCINE DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21478">
        <property type="entry name" value="GcvP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="8">
        <location>
            <begin position="96"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="8">
        <location>
            <begin position="581"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine dehydrogenase C-terminal" evidence="9">
        <location>
            <begin position="895"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EAQ71488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA45838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1084" mass="118017" checksum="6762C40A7007462E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHI0</accession>
    <name>G5EHI0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGCH7_ch7g888</name>
        <name evidence="5" type="ORF">MGG_03085</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15</strain>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720588.1">
        <property type="nucleotide sequence ID" value="XM_003720540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHI0"/>
    <dbReference type="SMR" id="G5EHI0"/>
    <dbReference type="GeneID" id="2682638"/>
    <dbReference type="KEGG" id="mgr:MGG_03085"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03085"/>
    <dbReference type="eggNOG" id="KOG3017">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035730_5_0_1"/>
    <dbReference type="OMA" id="NHNVHRS"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.33.10:FF:000018">
        <property type="entry name" value="SCP-like extracellular protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834264" description="SCP domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="108"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EAQ71481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA45845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="279" mass="29906" checksum="70697C0207D7886D" modified="2011-12-14" version="1">MRASLCLVASGAILALAGPLEIRGIHTEFVTDIVYVTVTEDDSEPTSSPVLEQSTPVMTSTSSVQSPVSTTHQPQETSAAAAQPNVPVENIKKQQSNSNSKASKGTNAFQNTAVYHHNIHRENNSASALEWDSTYAGYAAETGKSCKFAHDLSPGGGGYGQNLAMWGSSNDPEKLGANTAIAQAITNMWYNGEITLYPSENYGLDNPVSGNFEKYGHYTQVVWAGTKKVGCHAQFCPKGTMFKDMGAWFSVCNYYPAGNMGGEYGKNVLKPQNKQTISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHX8</accession>
    <name>G5EHX8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGCH7_ch7g177</name>
        <name evidence="6" type="ORF">MGG_09014</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15</strain>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">70-15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-beta-HSD family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721327.1">
        <property type="nucleotide sequence ID" value="XM_003721279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHX8"/>
    <dbReference type="STRING" id="242507.G5EHX8"/>
    <dbReference type="GeneID" id="2680137"/>
    <dbReference type="KEGG" id="mgr:MGG_09014"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09014"/>
    <dbReference type="eggNOG" id="KOG1430">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045580_1_0_1"/>
    <dbReference type="OMA" id="PTWVNHI"/>
    <dbReference type="OrthoDB" id="10058185at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF51">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="4">
        <location>
            <begin position="86"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EAQ70770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA46584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="507" mass="56078" checksum="C552584523375B6F" modified="2011-12-14" version="1">MELPPVIDCVRIVFVASVLLVLLLGLIYLSILNWAMCGTPTHVKKVTQKHWTKDQVKEKYEAVKEKPMTINSITPKLPPQLQRRYIITGGSGLVGGYLVLLLIARGQPPESIRIVDFQKPHRNDMVVGPAAEVDFVKTDISSKKAVAEAFARPWHPSVEHLPLTVFHTAAVIVPSDRSELVYGLCQKVNIEGTRILVEEAQAAGADVFIATSSGSISIRPVEFWISPWELLTKGPRHHAQVLDESDFWKPLRPHNEFFGNYPASKAFAERIVCGANSDKMRTGSIRPANGIYGNPTDNIIGGPLALGIFPSWNPQIVQSYIHALNCAIAHLNLEAVLDPTDSASRPQAGRPFTVTDPNPPITNKTLWSMIATLSITSFRTVRILCPVVILMVAYAIEWYALLPHRYPRLKHIIPPLNNDIKHLKPPLFSITTHLIANHQGDATKPISEGGIGYTGLTTTMDGMVQEVLEWNQEHEGVSRRNRRKYISSVTLAEEIRKLGEAAMAVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI28</accession>
    <name>G5EI28_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGCH7_ch7g277</name>
        <name evidence="4" type="ORF">MGG_02564</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15</strain>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721239.1">
        <property type="nucleotide sequence ID" value="XM_003721191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI28"/>
    <dbReference type="SMR" id="G5EI28"/>
    <dbReference type="GeneID" id="2682302"/>
    <dbReference type="KEGG" id="mgr:MGG_02564"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02564"/>
    <dbReference type="HOGENOM" id="CLU_921587_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834290" evidence="2">
        <location>
            <begin position="23"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EAQ70870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="302" mass="32341" checksum="DE78A928A0108ECC" modified="2011-12-14" version="1">MRPTNLFEFLALAASIVPAAIASSSPGQSLRTGSPRSRTVSPPAIVAGSPPVSPRLEADSQGALTAAELEEVKRLTPEQFGQWLRKHEDAAGAATQPQHAQHGLPPSPGARGHSQDLSHQKAEGSAGLNRGARHNIDFDGYFRKRDLQPKLAPRSRPGRDSSQVKRRSSPKQEQNVPEASQASMLGKLRGKAATCMQVCGAAISRLGAKAKQPRSGNGNTNPTPPGPCWCAECVDSGNNGWHSHEGRKKLQASSLEDLLSECRAIQTEVDDLRARLTAQLAEAQERERLQKGTQSSKQVGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4L4</accession>
    <name>A0A151V4L4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14979</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165178">
        <property type="protein sequence ID" value="KYQ30519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846023.1">
        <property type="nucleotide sequence ID" value="XM_016990548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4L4"/>
    <dbReference type="GeneID" id="27922172"/>
    <dbReference type="KEGG" id="mgr:MGG_14979"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14979"/>
    <dbReference type="InParanoid" id="A0A151V4L4"/>
    <dbReference type="OMA" id="SEESGHC"/>
    <dbReference type="OrthoDB" id="5427664at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KYQ30519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="138" mass="15482" checksum="70DB9F72776B71F9" modified="2016-06-08" version="1">MGPGLESIAKQTREFLGTLCDLQILTGLAITIAGWTQHATISYYHQQLVLAYWSLALNSFWAARVQYLDVDSKNDDGTETRDTIRCIAVLCNCLVALTFNIHVEIREQQAWDDDGGPCYNFLDGTSSLVEYPIGYKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4QPW2</accession>
    <name>A4QPW2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711122.1">
        <property type="nucleotide sequence ID" value="XM_003711074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4QPW2"/>
    <dbReference type="GeneID" id="12986921"/>
    <dbReference type="KEGG" id="mgr:MGG_16554"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16554"/>
    <dbReference type="HOGENOM" id="CLU_073890_0_0_1"/>
    <dbReference type="InParanoid" id="A4QPW2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="257" mass="27565" checksum="BB507281E219DD14" modified="2007-05-15" version="1">MERKNGRGPGEAKAGPRRALLYIKYTTPRTERGRKASISGAEAGSNKAPDELGGRARMGEARARPQRRPGKALDEKHLEKVLYVDGSGALSTTTFSTAITAITATTATNPPACSANLYIYIQNVLCWEGPWAGKEAVWGPDDTKPYVQNGPGWAGTKDGRASRHEALYIKCIVLGGKQAGPADTKFDGQNMLQPTPNYMHNVCDPGTEQCRKASIRHPAHSGGQGPDGPGGWTRTGEARGGPPRRPGPEYTNFSMSY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-07-10" modified="2025-06-18" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4QX49</accession>
    <accession>G4N0I4</accession>
    <name>DBP7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>ATP-dependent RNA helicase DBP7</fullName>
            <ecNumber>3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">DBP7</name>
        <name type="ORF">MGG_05810</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text>The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="miscellaneous">
        <text>Present with 1460 molecules/cell in log phase SD medium.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712125.1">
        <property type="nucleotide sequence ID" value="XM_003712077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4QX49"/>
    <dbReference type="SMR" id="A4QX49"/>
    <dbReference type="FunCoup" id="A4QX49">
        <property type="interactions" value="738"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4QX49"/>
    <dbReference type="EnsemblFungi" id="MGG_05810T0">
        <property type="protein sequence ID" value="MGG_05810T0"/>
        <property type="gene ID" value="MGG_05810"/>
    </dbReference>
    <dbReference type="GeneID" id="2684165"/>
    <dbReference type="KEGG" id="mgr:MGG_05810"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05810"/>
    <dbReference type="eggNOG" id="KOG0348">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_26_2_1"/>
    <dbReference type="InParanoid" id="A4QX49"/>
    <dbReference type="OMA" id="AVHIKAD"/>
    <dbReference type="OrthoDB" id="422663at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000464">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17949">
        <property type="entry name" value="DEADc_DDX31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <feature type="chain" id="PRO_0000294643" description="ATP-dependent RNA helicase DBP7">
        <location>
            <begin position="1"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="164"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="400"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="21"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="457"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="632"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="676"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="764"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif">
        <location>
            <begin position="131"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEAD box">
        <location>
            <begin position="302"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="470"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="646"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="676"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="786"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="177"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="825" mass="89217" checksum="6F4FE8EFBCB786E3" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-09-11" modified="2025-06-18" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>A4R4R3</accession>
    <accession>G4NGY5</accession>
    <name>TOF1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Topoisomerase 1-associated factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">TOF1</name>
        <name type="ORF">MGG_03991</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
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                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
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        <text evidence="1">Forms a fork protection complex (FPC) with CSM3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors.</text>
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        <text evidence="1">Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.</text>
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            <location evidence="1">Nucleus</location>
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        <text evidence="3">Belongs to the timeless family.</text>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_03991"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PROTEIN TIMELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TIMEOUT/TIMELESS-2"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF04821">
        <property type="entry name" value="TIMELESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0236">DNA replication inhibitor</keyword>
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    <keyword id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="1214"/>
        </location>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MK88</accession>
    <name>G4MK88_PYRO7</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">MGG_16131</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709291.1">
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_16131"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLQ4</accession>
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        <submittedName>
            <fullName evidence="7">Acriflavine sensitivity control protein acr-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05434</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003710246.1"/>
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    <dbReference type="STRING" id="242507.G4MLQ4"/>
    <dbReference type="GeneID" id="2675951"/>
    <dbReference type="KEGG" id="mgr:MGG_05434"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05434"/>
    <dbReference type="eggNOG" id="ENOG502SI0U">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_020030_3_1_1"/>
    <dbReference type="InParanoid" id="G4MLQ4"/>
    <dbReference type="OMA" id="KQKAMGH"/>
    <dbReference type="OrthoDB" id="5380854at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF51">
        <property type="entry name" value="ACRIFLAVINE SENSITIVITY CONTROL PROTEIN ACR-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA57682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="592" mass="65138" checksum="2FEE10F5EC5352E7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLQ8</accession>
    <name>G4MLQ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hsc70 cochaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05438</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SGT family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710298.1">
        <property type="nucleotide sequence ID" value="XM_003710250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLQ8"/>
    <dbReference type="SMR" id="G4MLQ8"/>
    <dbReference type="FunCoup" id="G4MLQ8">
        <property type="interactions" value="616"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MLQ8"/>
    <dbReference type="GeneID" id="2675955"/>
    <dbReference type="KEGG" id="mgr:MGG_05438"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05438"/>
    <dbReference type="eggNOG" id="KOG0553">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044224_1_1_1"/>
    <dbReference type="InParanoid" id="G4MLQ8"/>
    <dbReference type="OMA" id="DMARNMM"/>
    <dbReference type="OrthoDB" id="2335338at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.420:FF:000005">
        <property type="entry name" value="Hsc70 cochaperone (SGT), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000207">
        <property type="entry name" value="Small glutamine-rich tetratricopeptide repeat-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000011">
        <property type="entry name" value="TPR Domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032374">
        <property type="entry name" value="SGTA_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF2">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16546">
        <property type="entry name" value="SGTA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="173"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="6">
        <location>
            <begin position="263"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA57686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="353" mass="35973" checksum="998A6300F2FE3877" modified="2011-12-14" version="1">MSTTSQQRLALAICDFLNTSAKDGTLAADDSESIEVAVNCIAECFKVDPTDKAAVTAAVGDQNLLKIYGVYEKLKGTGSSSSAANSSAPAPAASAAPTDEQKKQADALKSKGNAAMAQKDYPQAIDLYTQALALHPGNAIYLSNRAAAHSAAKDHESARADAEAAVAVDPNYTKAWSRLGLARFALGDAKGSMEAYQKGIEYEGNGGSDAMKKGFETAKRRVEEMDLDTTRGPGGPGAGGMPDLSSLASILGGGAGRGEGGGMPDFASIMQNPMFASMAQNLMSNPDLMNNLMSNPRLREMANSFGGGGGGGMPDMSQLMSDPSIAEMARSMMGGGGPGAGPNAGPGAGRGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM01</accession>
    <name>G4MM01_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-L-fucosidase</fullName>
            <ecNumber evidence="2">3.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06780</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 29 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.51" evidence="2"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709498.1">
        <property type="nucleotide sequence ID" value="XM_003709450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM01"/>
    <dbReference type="SMR" id="G4MM01"/>
    <dbReference type="STRING" id="242507.G4MM01"/>
    <dbReference type="CAZy" id="GH29">
        <property type="family name" value="Glycoside Hydrolase Family 29"/>
    </dbReference>
    <dbReference type="GeneID" id="2684953"/>
    <dbReference type="KEGG" id="mgr:MGG_06780"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06780"/>
    <dbReference type="eggNOG" id="KOG3340">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002934_7_1_1"/>
    <dbReference type="InParanoid" id="G4MM01"/>
    <dbReference type="OMA" id="HFNMNTF"/>
    <dbReference type="OrthoDB" id="6039950at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016139">
        <property type="term" value="P:glycoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000933">
        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057739">
        <property type="entry name" value="Glyco_hydro_29_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030:SF37">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01120">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00812">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465820" description="alpha-L-fucosidase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="7">
        <location>
            <begin position="374"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA56886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="519" mass="58049" checksum="658C0194DE61B4AE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMS0</accession>
    <name>G4MMS0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003708714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMS0"/>
    <dbReference type="SMR" id="G4MMS0"/>
    <dbReference type="STRING" id="242507.G4MMS0"/>
    <dbReference type="GeneID" id="2681642"/>
    <dbReference type="KEGG" id="mgr:MGG_02016"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02016"/>
    <dbReference type="eggNOG" id="KOG0575">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_425171_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMS0"/>
    <dbReference type="OMA" id="AWMEIVE"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="311"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="584" mass="65102" checksum="B3147BEDB573A0F5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNB0</accession>
    <name>G4MNB0_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02077</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708845.1">
        <property type="nucleotide sequence ID" value="XM_003708797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNB0"/>
    <dbReference type="GeneID" id="2681232"/>
    <dbReference type="KEGG" id="mgr:MGG_02077"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02077"/>
    <dbReference type="HOGENOM" id="CLU_1896633_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNB0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="134" mass="14329" checksum="8C1D905C84789BA1" modified="2011-12-14" version="1">MVEPTKDLELASPGSSLSLAGGASSRNSRWAVTLLALSNVVTLAVLLRPAGPHKQQDFNDAAKARGAQGPRLEQGAPEPLLGLSAAEHHVRGRGERRTNNNWGLLRGEGERIPLKKDKRVNRWTGQPKTAATGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNH1</accession>
    <name>G4MNH1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709697.1">
        <property type="nucleotide sequence ID" value="XM_003709649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNH1"/>
    <dbReference type="STRING" id="242507.G4MNH1"/>
    <dbReference type="GeneID" id="2685126"/>
    <dbReference type="KEGG" id="mgr:MGG_06953"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06953"/>
    <dbReference type="eggNOG" id="ENOG502T0FS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122522_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNH1"/>
    <dbReference type="OMA" id="TSDYCED"/>
    <dbReference type="OrthoDB" id="5596743at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012790976" evidence="1">
        <location>
            <begin position="16"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="138" mass="14364" checksum="16913D618477A5E3" modified="2011-12-14" version="1">MKVIAILSLVSLAFGSVVEKRECAGNNCNRAITGVQDRPAPLSVRQADCSSFQTTVVTPPATTVTVTVEAEGTAVIKRDAILEIRQATSNVKPTYATACSSDAAYASACNCWGITSAVSTAPTPTVTVTSTIDYCDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNL0</accession>
    <name>G4MNL0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA mismatch repair protein MSH5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MutS protein homolog 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_05639</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710529.1">
        <property type="nucleotide sequence ID" value="XM_003710481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNL0"/>
    <dbReference type="SMR" id="G4MNL0"/>
    <dbReference type="FunCoup" id="G4MNL0">
        <property type="interactions" value="142"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MNL0"/>
    <dbReference type="GeneID" id="2676041"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05639"/>
    <dbReference type="eggNOG" id="KOG0221">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4MNL0"/>
    <dbReference type="OrthoDB" id="29596at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051026">
        <property type="term" value="P:chiasma assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03281">
        <property type="entry name" value="ABC_MSH5_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001067">
        <property type="entry name" value="DNA mismatch repair protein MSH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0469">Meiosis</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="13">
        <location>
            <begin position="772"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="669"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="670"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00073549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA57917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="947" mass="103850" checksum="CE1B4771A6532638" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNN9</accession>
    <name>G4MNN9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-ketosteroid-delta-1-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02098</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708867.1">
        <property type="nucleotide sequence ID" value="XM_003708819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNN9"/>
    <dbReference type="SMR" id="G4MNN9"/>
    <dbReference type="STRING" id="242507.G4MNN9"/>
    <dbReference type="GeneID" id="2681189"/>
    <dbReference type="KEGG" id="mgr:MGG_02098"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02098"/>
    <dbReference type="eggNOG" id="ENOG502SIS7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022946_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNN9"/>
    <dbReference type="OMA" id="PEDHWPR"/>
    <dbReference type="OrthoDB" id="3345469at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014614">
        <property type="entry name" value="KsdD_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009472">
        <property type="entry name" value="PRK12834.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260">
        <property type="entry name" value="3-KETOSTEROID-DELTA-1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43260:SF1">
        <property type="entry name" value="KSDD-LIKE STEROID DEHYDROGENASE RV0785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036654">
        <property type="entry name" value="UCP036654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="3">
        <location>
            <begin position="9"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="572" mass="62230" checksum="004AA558F3732199" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNP6</accession>
    <name>G4MNP6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708874.1">
        <property type="nucleotide sequence ID" value="XM_003708826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNP6"/>
    <dbReference type="GeneID" id="2681195"/>
    <dbReference type="KEGG" id="mgr:MGG_02104"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02104"/>
    <dbReference type="eggNOG" id="ENOG502TH3H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054978_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNP6"/>
    <dbReference type="OMA" id="WHISRRD"/>
    <dbReference type="OrthoDB" id="5421765at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="415" mass="46438" checksum="C29F0D6DCF78DB64" modified="2011-12-14" version="1">MGGSSSKGASPFPLTNFQDSLLTPPDDTSVRQTWTILRSAIDSHARRFYHTDSVYHSREQIRESIHEAGVVDDAQEAEDLATLLHSPRHRRMGLRICIARVMVSSIDFYSHPDETSLDPAVVELMRRFDELRPELGKEEEAALAAWRMITAFFLQPGAQDHHALVKPCVATLERILVVFARSNSPTERELRLSGIAAVSTRAVELGEKLFCHAARWRFEWRPPVEEVDEKPHYYSGGRDGRRSIVIFPALLRSDDDGPKKRGGINYVIIKRKAVSAGSFFDVPPPADGDGSSSSSSSSSSSSDDDDAPSRKAPSRGRGKSSFLESIYSSYSSRSIRSLYHKARHKYRERTSVWFTVELNKIADGSNLLPPPSERFKTKLERLRCGECGSVVVKEYGLRWAVNGYLLKIVLVEATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNR7</accession>
    <name>G4MNR7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708895.1">
        <property type="nucleotide sequence ID" value="XM_003708847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNR7"/>
    <dbReference type="STRING" id="242507.G4MNR7"/>
    <dbReference type="GeneID" id="2681246"/>
    <dbReference type="KEGG" id="mgr:MGG_02123"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02123"/>
    <dbReference type="eggNOG" id="KOG0742">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_372571_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNR7"/>
    <dbReference type="OMA" id="HLGKIWG"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411:SF2">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46411">
        <property type="entry name" value="FAMILY ATPASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="512"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="746" mass="83978" checksum="D9718966B8969738" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNZ7</accession>
    <name>G4MNZ7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710558.1">
        <property type="nucleotide sequence ID" value="XM_003710510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNZ7"/>
    <dbReference type="GeneID" id="12986376"/>
    <dbReference type="KEGG" id="mgr:MGG_16439"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16439"/>
    <dbReference type="HOGENOM" id="CLU_1993056_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNZ7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="125" mass="14136" checksum="89B14EB9B395A264" modified="2011-12-14" version="1">MHLDGTSQETITYFTVLAYFEPFRYEKLAARVTAESSRRIIDAMEMGFSVPLCTACTALSCQGMHPEHSRVYKSISWGLAKYTPSLDSTALRRIAQRQQVEAVESFVFHYSILFSNIFGQSVVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPE7</accession>
    <name>G4MPE7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ent-kaurene oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_09198</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709812.1">
        <property type="nucleotide sequence ID" value="XM_003709764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPE7"/>
    <dbReference type="SMR" id="G4MPE7"/>
    <dbReference type="GeneID" id="2680242"/>
    <dbReference type="KEGG" id="mgr:MGG_09198"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09198"/>
    <dbReference type="eggNOG" id="KOG0159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_2_1"/>
    <dbReference type="InParanoid" id="G4MPE7"/>
    <dbReference type="OMA" id="WARKESM"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF6">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AN1598-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="457"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA57200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="557" mass="63324" checksum="5EDB88F04AB6AFDB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPF5</accession>
    <name>G4MPF5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_05710</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710610.1">
        <property type="nucleotide sequence ID" value="XM_003710562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPF5"/>
    <dbReference type="GeneID" id="2675906"/>
    <dbReference type="KEGG" id="mgr:MGG_05710"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05710"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_4_4_1"/>
    <dbReference type="InParanoid" id="G4MPF5"/>
    <dbReference type="OMA" id="GMMTLFM"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF64">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="475"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA57998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="57059" checksum="279818E5728153A2" modified="2011-12-14" version="1">MGLFDKFAFAKRHERTPEERAYVRKLDICLMTFGCISQIMKYLDQTNINNAYVSGMKEDLQLYGDELNYFTTFFLLGNLIMVVPSQIALTYIPPNWWLPGLEITWGVLTGLFAVTKNARDIYALRFFLGMCESSAWPGMMTMMIYWYTPSEIAKRMGIYQCSQAVGSMMSGALAISVVKTMDGKGGLAAWRWLFIVECLMTVVVGCFGFLMVPGLPHKPNPWAFWFKESDAKLAMKRLHRHGKQEPVKITLKTIKRSLASPLFYAIVPLSMGANMANYGMYYFGVFLKSLKNADGTPRWNVTEVNGIPIGGSGVSIVALLIFTNLSDLFQSRWTIFMAQAIIGLFATIYMTVWTAHPDTTPIGGAYASYFMLYMTIGVTLIVTAWLSDLLPHDPDSVTFIIGATVALNFAILSWAQALMWPASKAPYYVHGWGSSIGIWLFCMLMVAAVWYIDRRYLKAKRQAFRETLINTDVEESDKVGPASRQDEGEPELADKGPAIPQAAEAKQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPQ2</accession>
    <name>G4MPQ2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_02243</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709013.1">
        <property type="nucleotide sequence ID" value="XM_003708965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPQ2"/>
    <dbReference type="SMR" id="G4MPQ2"/>
    <dbReference type="STRING" id="242507.G4MPQ2"/>
    <dbReference type="GeneID" id="2681340"/>
    <dbReference type="KEGG" id="mgr:MGG_02243"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02243"/>
    <dbReference type="eggNOG" id="KOG3968">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_11_1_1"/>
    <dbReference type="InParanoid" id="G4MPQ2"/>
    <dbReference type="OMA" id="RVFWSYA"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF37">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465463" evidence="5">
        <location>
            <begin position="19"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="6">
        <location>
            <begin position="79"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA56401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="504" mass="54846" checksum="F45C6EF0BE3D01D0" modified="2011-12-14" version="1">MRQATVAATLALLGSASAASTLFNGGTIVAFDAETQGLRVVRNGSLLVTDDRIAGIYTSPPAAQQNSSSIEVVDASGKIITPGFIDTHRHGWQTAFKTLGSNTSLTEYFGRYGEFASASHWDADDVYASQLAGLYEAANAGVTTSLDHAHSTWDKATSEAGLKASVDSGSRVFYAFTFHNTTASEIPELLQVFRDIADEGYYQGSPTTLGIAYDAWGPDPNRAEIDSIMQLTEDYNISVITTHSLGGPWGITNSPSDVAALDYLNISTPIVFSHASFLAAGDAILLRETNQHISITPESEMHYGHTHPNSHLIQDQAALGVDTHFTFSTDILTQARIWLQQARYDESEKVLDEWRLPLNNPMSTDQAFLLATRSGGLALHRDDLGVIREGAKADLVVWDGESPAMLGWLDPVAAVILHASVGDIESVMVDGKWVKKDRKLVVGDYADVKRRFLATAKKIQDIWVDTPLPTPEELQSMFPFPLVRADQLDVQRGEGNGYGENHFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPW1</accession>
    <name>G4MPW1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709870.1">
        <property type="nucleotide sequence ID" value="XM_003709822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPW1"/>
    <dbReference type="STRING" id="242507.G4MPW1"/>
    <dbReference type="GeneID" id="2680233"/>
    <dbReference type="KEGG" id="mgr:MGG_09244"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09244"/>
    <dbReference type="eggNOG" id="ENOG502SM1Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022339_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPW1"/>
    <dbReference type="OMA" id="IWVPVWG"/>
    <dbReference type="OrthoDB" id="5281682at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="652" mass="72753" checksum="F2F78D665B127BD5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPZ2</accession>
    <name>G4MPZ2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710692.1">
        <property type="nucleotide sequence ID" value="XM_003710644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPZ2"/>
    <dbReference type="GeneID" id="2676078"/>
    <dbReference type="KEGG" id="mgr:MGG_05766"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05766"/>
    <dbReference type="eggNOG" id="ENOG502SVII">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069188_1_0_1"/>
    <dbReference type="InParanoid" id="G4MPZ2"/>
    <dbReference type="OMA" id="CCHVWEY"/>
    <dbReference type="OrthoDB" id="5207784at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="287" mass="31175" checksum="E1E53E2B451C8272" modified="2011-12-14" version="1">MPEASSSAEQSGSKPLPDQEVEPQEPVPSPDTQEPTEAALPPYEQVPPPGQEILAPTTLVLAGQAIHALTTDSPALYHLSLGISELSAITSEVELSRVDTKGRDRPIYELRHLKAPAGGMYPMPSESPQYHIQRANKRVSGPAAVGLKKTRSLLSRKITGLSAVPVDPSGKASKFGIPTFVKNAAPVLTTDGREWKDAQNKTIALVHDDRDDKQHSLIVTEAMPRSQFDMLVALWCCHIWEFGVAHADKVHEGVNGLKRKLRQSREFGMMYSAAPLGMIGTSSKFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQA4</accession>
    <name>G4MQA4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709909.1">
        <property type="nucleotide sequence ID" value="XM_003709861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQA4"/>
    <dbReference type="SMR" id="G4MQA4"/>
    <dbReference type="STRING" id="242507.G4MQA4"/>
    <dbReference type="GeneID" id="5049530"/>
    <dbReference type="KEGG" id="mgr:MGG_09273"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09273"/>
    <dbReference type="eggNOG" id="ENOG502RCSS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008719_4_1_1"/>
    <dbReference type="InParanoid" id="G4MQA4"/>
    <dbReference type="OMA" id="RTGWPMA"/>
    <dbReference type="OrthoDB" id="5319341at2759"/>
    <dbReference type="PHI-base" id="PHI:5647"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF3">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="657"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="675"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="820" mass="90090" checksum="F6A867092D5674A1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQH9</accession>
    <name>G4MQH9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_02313</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709081.1">
        <property type="nucleotide sequence ID" value="XM_003709033.1"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MQH9"/>
    <dbReference type="GeneID" id="2681410"/>
    <dbReference type="KEGG" id="mgr:MGG_02313"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02313"/>
    <dbReference type="eggNOG" id="ENOG502QUFK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000211_1_0_1"/>
    <dbReference type="InParanoid" id="G4MQH9"/>
    <dbReference type="OMA" id="DIMHTPM"/>
    <dbReference type="OrthoDB" id="3182339at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022099">
        <property type="entry name" value="DUF3638"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022105">
        <property type="entry name" value="DUF3645"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046541">
        <property type="entry name" value="DUF6606"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF34">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12340">
        <property type="entry name" value="DUF3638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12359">
        <property type="entry name" value="DUF3645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20255">
        <property type="entry name" value="DUF6606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUF6606" evidence="10">
        <location>
            <begin position="58"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3638" evidence="8">
        <location>
            <begin position="2187"/>
            <end position="2416"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3645" evidence="9">
        <location>
            <begin position="2540"/>
            <end position="2573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="958"/>
            <end position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA56469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="3298" mass="371628" checksum="DD123E6A50048A0D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR67</accession>
    <name>G4MR67_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710011.1">
        <property type="nucleotide sequence ID" value="XM_003709963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR67"/>
    <dbReference type="SMR" id="G4MR67"/>
    <dbReference type="STRING" id="242507.G4MR67"/>
    <dbReference type="GeneID" id="2680883"/>
    <dbReference type="KEGG" id="mgr:MGG_09913"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09913"/>
    <dbReference type="eggNOG" id="KOG0427">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_15_0_1"/>
    <dbReference type="InParanoid" id="G4MR67"/>
    <dbReference type="OMA" id="WQMDIKV"/>
    <dbReference type="OrthoDB" id="406833at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 W"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
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        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
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        <location>
            <begin position="5"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="155" mass="17763" checksum="FE2D2FDF794E7DE9" modified="2011-12-14" version="1">MAASFANKRLSKELIKIKESLPPGILLISADNFEEWLLDIKVLDNNPLYANETYRLKFRFSSSYPIEPPEVVFAKLPDRPIPIHPHIYSNGIICLDLLGQQGWSPVQNVESVCMSLQSMLTGNTKNERPPGDEEFVRSNRARPRDIDFYYHDNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR91</accession>
    <name>G4MR91_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TOM core complex subunit Tom6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_13775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710828.1">
        <property type="nucleotide sequence ID" value="XM_003710780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR91"/>
    <dbReference type="SMR" id="G4MR91"/>
    <dbReference type="GeneID" id="5048995"/>
    <dbReference type="KEGG" id="mgr:MGG_13775"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13775"/>
    <dbReference type="eggNOG" id="ENOG502SY3V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183924_0_0_1"/>
    <dbReference type="InParanoid" id="G4MR91"/>
    <dbReference type="OMA" id="QSPFSEW"/>
    <dbReference type="OrthoDB" id="5222813at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA58216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="65" mass="6917" checksum="67804C229726ADD6" modified="2011-12-14" version="1">MPPKVVRVQPAGGRSRPAQPRGVVGATYDFITAPEYASVVRSVAAFGVGVAFLASSFGEYFDPQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS60</accession>
    <name>G4MS60_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710930.1">
        <property type="nucleotide sequence ID" value="XM_003710882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS60"/>
    <dbReference type="STRING" id="242507.G4MS60"/>
    <dbReference type="GeneID" id="2677917"/>
    <dbReference type="KEGG" id="mgr:MGG_04554"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04554"/>
    <dbReference type="eggNOG" id="ENOG502S233">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008809_1_2_1"/>
    <dbReference type="InParanoid" id="G4MS60"/>
    <dbReference type="OMA" id="CPELWNS"/>
    <dbReference type="OrthoDB" id="5322539at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041:SF6">
        <property type="entry name" value="FORMYLMETHIONINE DEFORMYLASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35041">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="594"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="689" mass="75418" checksum="CDBB43D10BC586B4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSJ4</accession>
    <name>G4MSJ4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_15703</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714417.1">
        <property type="nucleotide sequence ID" value="XM_003714369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSJ4"/>
    <dbReference type="SMR" id="G4MSJ4"/>
    <dbReference type="STRING" id="242507.G4MSJ4"/>
    <dbReference type="GeneID" id="12984657"/>
    <dbReference type="KEGG" id="mgr:MGG_15703"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15703"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099298_2_1_1"/>
    <dbReference type="InParanoid" id="G4MSJ4"/>
    <dbReference type="OMA" id="PAYIGRE"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465364" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA54610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="149" mass="16462" checksum="318E6EEA94AA1B3C" modified="2011-12-14" version="1">MWINRAALVLGLASFWIQQALSIVIPVERAATELLPKYDYIIVGGGLSGLVVGNRLSEDPNVTVLILEAGELDNRTEYTTYPAYIGREITNVNGWTLATTPQDHLDHRSRPYPQGRGVGGGTLIHGMVWTRGSKRDFDAWRDLGNPGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSM8</accession>
    <name>G4MSM8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715256.1">
        <property type="nucleotide sequence ID" value="XM_003715208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSM8"/>
    <dbReference type="GeneID" id="5050928"/>
    <dbReference type="KEGG" id="mgr:MGG_12330"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12330"/>
    <dbReference type="HOGENOM" id="CLU_980301_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSM8"/>
    <dbReference type="OMA" id="TEGHRYQ"/>
    <dbReference type="OrthoDB" id="5242444at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="284" mass="30505" checksum="BA25E7A9FB8FD350" modified="2011-12-14" version="1">MTTAPEQAPTDTLTTQTATATTTTTTTSTSEQVPTETLTTETFSMSTTSEQTPTDTLTTQTPTITTTYDQAPTDTLTTQTPSASTSPSDPSPTTSTVSETPSTSAPPPSTPTEPATPPGTLNTASGNRTVDYKKTVEGSRTEEINTTHAFDKWESGTIQYEGQMIYIVNKTTDLNMTSEILTSIAFDKKTQGLNQSLETNSTLEQQKVTDDTGSFESNRVTAGTRIIDGEKFAETVKSFEANRTADGVVYNKTTEGHRYQEGNSTTESSKIITSYGNDGHVEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTM4</accession>
    <name>G4MTM4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VTC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715389.1">
        <property type="nucleotide sequence ID" value="XM_003715341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTM4"/>
    <dbReference type="STRING" id="242507.G4MTM4"/>
    <dbReference type="GeneID" id="5050964"/>
    <dbReference type="KEGG" id="mgr:MGG_12369"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12369"/>
    <dbReference type="eggNOG" id="ENOG502QPI4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015126_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTM4"/>
    <dbReference type="OMA" id="HKTLDKQ"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42345:SF1">
        <property type="entry name" value="VTC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="696"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="795" mass="88814" checksum="E85F252850939D5D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTR8</accession>
    <name>G4MTR8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein DSF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713714.1">
        <property type="nucleotide sequence ID" value="XM_003713666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTR8"/>
    <dbReference type="SMR" id="G4MTR8"/>
    <dbReference type="STRING" id="242507.G4MTR8"/>
    <dbReference type="GeneID" id="2677863"/>
    <dbReference type="KEGG" id="mgr:MGG_04759"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04759"/>
    <dbReference type="eggNOG" id="ENOG502S2P6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033724_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTR8"/>
    <dbReference type="OMA" id="WGIKKDP"/>
    <dbReference type="OrthoDB" id="2148946at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010972">
        <property type="term" value="P:negative regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:001244">
        <property type="entry name" value="HCP-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="44359" checksum="7C696FD5C26A5F8A" modified="2011-12-14" version="1">MGLRDLLRKKDGIEADGPGANEQTVDQFGAQQQGHLRQPVTFIRTDTFNHEVIQPPGDPAAEQDGGRDKGNSMHGGDGNFLSPDGSKRRSFFSSGSSRSRGSSESSAHSPTADPGHKDKDKVFRRLSQRLHLARSPPSSENVPQNLPEIVIRPEEEASPAVESKWEERATILAMENERVRSRPPSPPGGGGGSSGDVSGGFAHMSIGDHAGPSGRKRSPSAVSSKALDDNIQEAIRLHEAGELEQSTKLFGKLADPEGDNNPLSQVLYGLALRHGWGCQPDPEGAVHYLSKAASNAATVETLALQAGMKKGGAAKGELVLAIFELANCFRHGWGVQKDPVAAKQYYETAANLGDTDAMNEVAWCYLEGFGCKKDKFASAKYYRLAEKSGNKTLGNSWIWKEKYDPGNNGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTV6</accession>
    <name>G4MTV6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pre-mRNA branch site protein p14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_01579</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714557.1">
        <property type="nucleotide sequence ID" value="XM_003714509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTV6"/>
    <dbReference type="SMR" id="G4MTV6"/>
    <dbReference type="STRING" id="242507.G4MTV6"/>
    <dbReference type="GeneID" id="2679525"/>
    <dbReference type="KEGG" id="mgr:MGG_01579"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01579"/>
    <dbReference type="eggNOG" id="KOG0114">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_25_2_1"/>
    <dbReference type="InParanoid" id="G4MTV6"/>
    <dbReference type="OMA" id="HQPDKMV"/>
    <dbReference type="OrthoDB" id="275748at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12241">
        <property type="entry name" value="RRM_SF3B14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000286">
        <property type="entry name" value="Putative pre-mRNA branch site protein p14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034150">
        <property type="entry name" value="SF3B6_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF58">
        <property type="entry name" value="RNA-BINDING PROTEIN 19-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="13"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="115" mass="13163" checksum="18464D7BE0149DF1" modified="2011-12-14" version="1">MSRVGKLAPEVNRALFVKNLSYNVTPEELFDLFGKFGPIRQVRQGIASNTKGTAFVVYEDVMDAKQACDKLNGFNFQNRYLVVLYHQPEKMARSKEDLEARKENLAQLKKQHGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTY9</accession>
    <name>G4MTY9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methylmalonate-semialdehyde dehydrogenase (CoA acylating)</fullName>
            <ecNumber evidence="2">1.2.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_01606</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.27" evidence="2"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714590.1">
        <property type="nucleotide sequence ID" value="XM_003714542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTY9"/>
    <dbReference type="SMR" id="G4MTY9"/>
    <dbReference type="STRING" id="242507.G4MTY9"/>
    <dbReference type="GeneID" id="2679307"/>
    <dbReference type="KEGG" id="mgr:MGG_01606"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01606"/>
    <dbReference type="eggNOG" id="KOG2449">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_10_1"/>
    <dbReference type="InParanoid" id="G4MTY9"/>
    <dbReference type="OMA" id="VEYATYV"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000002">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase (Acylating)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000003">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase [acylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866:SF3">
        <property type="entry name" value="METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="92"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA54783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="578" mass="61736" checksum="703B01A65A53D7C2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU36</accession>
    <name>G4MU36_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715443.1">
        <property type="nucleotide sequence ID" value="XM_003715395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU36"/>
    <dbReference type="SMR" id="G4MU36"/>
    <dbReference type="STRING" id="242507.G4MU36"/>
    <dbReference type="GeneID" id="5050976"/>
    <dbReference type="KEGG" id="mgr:MGG_12381"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12381"/>
    <dbReference type="eggNOG" id="ENOG502SAMX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2360131_0_0_1"/>
    <dbReference type="InParanoid" id="G4MU36"/>
    <dbReference type="OMA" id="HEFERHK"/>
    <dbReference type="OrthoDB" id="74240at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd20262">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045293">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="1">
        <location>
            <begin position="51"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="96" mass="10936" checksum="B74D3647BE7F1E3A" modified="2011-12-14" version="1">MAGTTVLRRHLSNAIAQSVRTGCRNYATPSSRPASRLGPTLDLESFIRRSKVMSLYRSFVRATYKIEDPQTRKETLQYFRSEFESNRGVTDSLTCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUH8</accession>
    <name>G4MUH8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715477.1">
        <property type="nucleotide sequence ID" value="XM_003715429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUH8"/>
    <dbReference type="GeneID" id="2683003"/>
    <dbReference type="KEGG" id="mgr:MGG_07257"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07257"/>
    <dbReference type="eggNOG" id="ENOG502T0D0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_584039_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUH8"/>
    <dbReference type="OrthoDB" id="3521097at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166:SF1">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38166">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="52560" checksum="9A86207D94A8F5B1" modified="2011-12-14" version="1">MAHHSYQDFRWLSPTTASQPTWDTRSSQATAASLSRTQSGALADPIDSYEDFSGDNGEGENMTAGRTRQRRSSTGPWASGNSISSNGDGTTTELWACPFCKWKPLRYQGCHTYKLKEISRVKQHLRRKHRIPPHCDVCAEEFADEEARLAHVRAQGCSMTQSCVQKTWEGVTPEQQELLERRAERNKTKVEQWYSIYEILFPGQTPPASPYVDLELSPQMHSFQAFLASDQAATILNEATIAQVPPHLQCEEILAISRAIFEQAMPALLQQYESSQQRRLSPRKPAEREIEDGQLSRVSSDTWMSVPPLIRRAGPPGLEEFGSGPMETDDNDLSTVSSPVTSVRLVAEPHGGEQQQRRPLGINTNMVAGAASHQIPRQQMQQQQQQQHQQQHQQHQRHRNDHDPTTPLQQQAGLWGLQHQSPLSPAFCGAWVNETATSQQEDIGGLGNPDMLYCHFDVYVPPYYGGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUI7</accession>
    <name>G4MUI7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715486.1">
        <property type="nucleotide sequence ID" value="XM_003715438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUI7"/>
    <dbReference type="GeneID" id="12986688"/>
    <dbReference type="KEGG" id="mgr:MGG_15890"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15890"/>
    <dbReference type="HOGENOM" id="CLU_2979572_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUI7"/>
    <dbReference type="OrthoDB" id="10410340at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="58" mass="6315" checksum="7A23CE894F52717A" modified="2011-12-14" version="1">MQADTSWSDLLLALLKVTTVTAFFGTSRSRDFGLASPNCRSPNKVFSQLCAYQQPSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUN6</accession>
    <name>G4MUN6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF803 domain membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_10187</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713816.1">
        <property type="nucleotide sequence ID" value="XM_003713768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUN6"/>
    <dbReference type="GeneID" id="2681814"/>
    <dbReference type="KEGG" id="mgr:MGG_10187"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10187"/>
    <dbReference type="eggNOG" id="KOG2922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012349_2_1_1"/>
    <dbReference type="InParanoid" id="G4MUN6"/>
    <dbReference type="OMA" id="GREQSHD"/>
    <dbReference type="OrthoDB" id="165382at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF65">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="134"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="690"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="695"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="759" mass="81506" checksum="F385BD7A4FE11A79" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVH0</accession>
    <name>G4MVH0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715603.1">
        <property type="nucleotide sequence ID" value="XM_003715555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVH0"/>
    <dbReference type="GeneID" id="2683081"/>
    <dbReference type="KEGG" id="mgr:MGG_07362"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07362"/>
    <dbReference type="HOGENOM" id="CLU_1277842_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVH0"/>
    <dbReference type="OrthoDB" id="10609375at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="216" mass="22225" checksum="A8CFEB1E55C165FC" modified="2011-12-14" version="1">MKYGEILVVLPTAVAAIHNPLPAAPEPHLAARQQATRTRTTSGLDESQATSCVSIFWAREALASSLEAEQPAPLTSYWSALYRSATDECGSVVAVQTAPPMPDPLLSIYADWESSARSAMFDSEPPLECDSVINDILLSRKQSRFAAQQTCLKAYSSSVAAVATAAATTGAASSTSAATTTTSAGTPANTGAAGRSGVSASLALSAMAVFGYFGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVS0</accession>
    <name>G4MVS0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714793.1">
        <property type="nucleotide sequence ID" value="XM_003714745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVS0"/>
    <dbReference type="GeneID" id="12985408"/>
    <dbReference type="KEGG" id="mgr:MGG_15765"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15765"/>
    <dbReference type="HOGENOM" id="CLU_1396588_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVS0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="195" mass="21582" checksum="AF6037997C27FAE9" modified="2011-12-14" version="1">MVSDLLGMELYFHRVQPKLPQPSRHIGQQDRQPHDLVEKGCHIKELVSVGSDAKGVKGASAAARSMSLKFSLAPAAWVMRCVDAQRAAGNQTYKCMRVVKSIPSYRPMVRFLAIHDVPRQDSKYTARPAGSGQAQMVGHTLCNASTLKLKRRPRQSDLGPAGIQSAQKRWVPIFRVVIYASDVCAQADWLQTEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW90</accession>
    <name>G4MW90_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">GPI ethanolamine phosphate transferase 1</fullName>
            <ecNumber evidence="14">2.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_01837</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="14"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714857.1">
        <property type="nucleotide sequence ID" value="XM_003714809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW90"/>
    <dbReference type="SMR" id="G4MW90"/>
    <dbReference type="FunCoup" id="G4MW90">
        <property type="interactions" value="486"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MW90"/>
    <dbReference type="GeneID" id="2679404"/>
    <dbReference type="KEGG" id="mgr:MGG_01837"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01837"/>
    <dbReference type="eggNOG" id="KOG2124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007676_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW90"/>
    <dbReference type="OMA" id="QSYFHRE"/>
    <dbReference type="OrthoDB" id="2748310at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16020">
        <property type="entry name" value="GPI_EPT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000015">
        <property type="entry name" value="GPI ethanolamine phosphate transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007070">
        <property type="entry name" value="GPI_EtnP_transferase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017852">
        <property type="entry name" value="GPI_EtnP_transferase_1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037671">
        <property type="entry name" value="PIGN_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250:SF0">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04987">
        <property type="entry name" value="PigN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 14" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="464"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="563"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="593"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="618"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="644"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="682"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="720"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="836"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="875"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="910"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="941"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="domain" description="GPI ethanolamine phosphate transferase 1 C-terminal" evidence="16">
        <location>
            <begin position="453"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="975"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="975"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA55050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1003" mass="110115" checksum="40BB1CF67481DD39" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWX2</accession>
    <name>G4MWX2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">MICOS complex subunit MIC60</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Mitofilin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_11278</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 13">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion inner membrane</location>
            <topology evidence="1 13">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MICOS complex subunit Mic60 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714071.1">
        <property type="nucleotide sequence ID" value="XM_003714023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWX2"/>
    <dbReference type="SMR" id="G4MWX2"/>
    <dbReference type="STRING" id="242507.G4MWX2"/>
    <dbReference type="GeneID" id="5051247"/>
    <dbReference type="KEGG" id="mgr:MGG_11278"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11278"/>
    <dbReference type="eggNOG" id="KOG1854">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008024_1_2_1"/>
    <dbReference type="InParanoid" id="G4MWX2"/>
    <dbReference type="OMA" id="RLDHQMQ"/>
    <dbReference type="OrthoDB" id="10261039at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019133">
        <property type="entry name" value="MIC60"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415:SF7">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415">
        <property type="entry name" value="MITOFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09731">
        <property type="entry name" value="Mitofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="39"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="176"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="354"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="434"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA54264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="697" mass="76016" checksum="174F406E5D866636" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYU5</accession>
    <name>G4MYU5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715131.1">
        <property type="nucleotide sequence ID" value="XM_003715083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYU5"/>
    <dbReference type="SMR" id="G4MYU5"/>
    <dbReference type="GeneID" id="2678365"/>
    <dbReference type="KEGG" id="mgr:MGG_08161"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08161"/>
    <dbReference type="eggNOG" id="ENOG502QSKG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_7_1_1"/>
    <dbReference type="InParanoid" id="G4MYU5"/>
    <dbReference type="OMA" id="MCADEDP"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF31">
        <property type="entry name" value="LAEA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="42894" checksum="D02EAE750222EFD1" modified="2011-12-14" version="1">MADEPRPEHEVGQGIGSSVGKDTTDPTEVPPSPTDQPVQPVQQPHGIYAGGVGDGDGSDVGDDDDDGDADSALDVRSIGTVSDSLTSSILRFRVENGRTYHSYKDGSYFMPNDDRENERLNLQHNLCMMTIGWKLYISPIDQRPVNRVLDIGCGTGVWSMEFADDHPEAHVIGIDLSPIQPSFVPPNVSYYIDDVEAEWTYSTPFDFIFTRMMLGCIRNWPEFFQQSFDNLTPGGYLESFEPVFPVRCEDDTYPQECALRKWFDLLDEGTKKVRSELPPLEVQKQRLVDAGFVNIVTREYKWPMNTWPSDKKQKEFGSLVLANLEEGIQGMTMAMFTRVLGWTKEQVELFLVDVRKDIRNTNMHVYYPIAVISAQKPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ85</accession>
    <name>G4MZ85_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aromatic amino acid aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08189</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715165.1">
        <property type="nucleotide sequence ID" value="XM_003715117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ85"/>
    <dbReference type="SMR" id="G4MZ85"/>
    <dbReference type="STRING" id="242507.G4MZ85"/>
    <dbReference type="GeneID" id="2678305"/>
    <dbReference type="KEGG" id="mgr:MGG_08189"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08189"/>
    <dbReference type="eggNOG" id="KOG0634">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_5_1"/>
    <dbReference type="InParanoid" id="G4MZ85"/>
    <dbReference type="OMA" id="QREGILC"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF1">
        <property type="entry name" value="AROMATIC AMINO ACID AMINOTRANSFERASE, HYPOTHETICAL (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="203"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="77"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA55358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="636" mass="71422" checksum="FFBF01EADAB4F819" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZD1</accession>
    <name>G4MZD1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04378</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713493.1">
        <property type="nucleotide sequence ID" value="XM_003713445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZD1"/>
    <dbReference type="SMR" id="G4MZD1"/>
    <dbReference type="FunCoup" id="G4MZD1">
        <property type="interactions" value="47"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_04378"/>
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        <property type="component" value="Chromosome 2"/>
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        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
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        <property type="evidence" value="ECO:0000250"/>
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            <begin position="68"/>
            <end position="90"/>
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        <location>
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            <end position="124"/>
        </location>
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            <begin position="165"/>
            <end position="182"/>
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            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
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            <end position="25"/>
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            <begin position="1"/>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA53686.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
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</entry>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    </feature>
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        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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    <organism evidence="3 4">
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711216.1">
        <property type="nucleotide sequence ID" value="XM_003711168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZW5"/>
    <dbReference type="STRING" id="242507.G4MZW5"/>
    <dbReference type="GeneID" id="2680096"/>
    <dbReference type="KEGG" id="mgr:MGG_09109"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09109"/>
    <dbReference type="eggNOG" id="ENOG502RXTA">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_014722_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZW5"/>
    <dbReference type="OMA" id="QNCFRCY"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
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    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
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    <dbReference type="PANTHER" id="PTHR43662">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF6">
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        <property type="match status" value="1"/>
    </dbReference>
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    <proteinExistence type="predicted"/>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="354" mass="38846" checksum="1C8568C98CF637E0" modified="2011-12-14" version="1">MITSTLLAFVATASAQALNSMTMLRFGCSQIVIDRLDPLVNPGVRGSPHVHQIVGGDGFNTTMTTGDVSKTAKCTTCAFSEDFSNYWTANLYFKARNGTYKRVPQGGAAFQFNDRFSTQTQGGILVYYASAQPGQITAFKPGFRMLVGDPMQRSRSDTTLKRQNCYRCYTGPNFGGDIMAPCQDDRVDSEMFPSKPCPGGIRTNIHFPTCWDGKNLDSPNHRDHVAYPVTGPANFLTLGGACPASHPVRIPQLMYEVVWDTTQFNDRSEWPEDGRSQPFVLSTGDDTGLGQHGDYVFGWEGDSLQRAMDRAGCYGAQCGTLKTQAIDVARKCEIPPKVEEDYDGWLSELPGTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0J3</accession>
    <name>G4N0J3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_07725</name>
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    <organism evidence="7 8">
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712931.1">
        <property type="nucleotide sequence ID" value="XM_003712883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0J3"/>
    <dbReference type="GeneID" id="2683652"/>
    <dbReference type="KEGG" id="mgr:MGG_07725"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07725"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1034678_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0J3"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA53124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="29839" checksum="000BB3BDEA261BEB" modified="2011-12-14" version="1">MTPGVKYAREISINCQLQLGYKRSEIVYILGTSTQKSTNKTRRKEKARGLEVGTWYFSLDFFYLDKKCISNVAAFGAMLSTISSHIYFPALVPMVRDLDVSVSLINLTVTSYLVVAGIVPAFMGDFADQSDRRPAYMLMVTLVFCANIGLALQKSYPALLVLRMLQSAGASGSYGIIADITTTAERRSIFWFLVILMGVYLVFVLLFLPETQRKIVGNASIPTRGLHRSVFDVFTGGSRQVEMTGIERGPVPSAKEKLQFSNPFKPLPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0N1</accession>
    <name>G4N0N1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Pyruvate carboxylase</fullName>
            <ecNumber evidence="4 13">6.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">MGG_07756</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>hydrogencarbonate + pyruvate + ATP = oxaloacetate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.1" evidence="4 13"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712969.1">
        <property type="nucleotide sequence ID" value="XM_003712921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0N1"/>
    <dbReference type="SMR" id="G4N0N1"/>
    <dbReference type="FunCoup" id="G4N0N1">
        <property type="interactions" value="647"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N0N1"/>
    <dbReference type="GeneID" id="2683683"/>
    <dbReference type="KEGG" id="mgr:MGG_07756"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07756"/>
    <dbReference type="eggNOG" id="KOG0369">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_1_1_1"/>
    <dbReference type="InParanoid" id="G4N0N1"/>
    <dbReference type="OMA" id="AEACICY"/>
    <dbReference type="OrthoDB" id="196847at2759"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004736">
        <property type="term" value="F:pyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07937">
        <property type="entry name" value="DRE_TIM_PC_TC_5S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000003">
        <property type="entry name" value="Acetyl-CoA carboxylase biotin carboxyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000018">
        <property type="entry name" value="Biotin carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000010">
        <property type="entry name" value="Propionyl-CoA carboxylase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000033">
        <property type="entry name" value="Pyruvate carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000012">
        <property type="entry name" value="Pyruvate carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055268">
        <property type="entry name" value="PCB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005930">
        <property type="entry name" value="Pyruv_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006761">
        <property type="entry name" value="PRK09282.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009554">
        <property type="entry name" value="PRK12999.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01235">
        <property type="entry name" value="pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43778">
        <property type="entry name" value="PYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43778:SF2">
        <property type="entry name" value="PYRUVATE CARBOXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001594">
        <property type="entry name" value="Pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89000">
        <property type="entry name" value="post-HMGL domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 13 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="21">
        <location>
            <begin position="43"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="20">
        <location>
            <begin position="165"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="22">
        <location>
            <begin position="581"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="19">
        <location>
            <begin position="1119"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1107"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="1107"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="active site" evidence="14">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="590"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="662"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="16">
        <location>
            <position position="758"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="788"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="790"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="923"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="17">
        <location>
            <position position="758"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-biotinyllysine" evidence="17">
        <location>
            <position position="1160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001594-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001594-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR001594-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR001594-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EHA53162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1197" mass="131706" checksum="28EA14C40EBEB0DA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0W7</accession>
    <name>G4N0W7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712152.1">
        <property type="nucleotide sequence ID" value="XM_003712104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0W7"/>
    <dbReference type="SMR" id="G4N0W7"/>
    <dbReference type="GeneID" id="12984921"/>
    <dbReference type="KEGG" id="mgr:MGG_16787"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16787"/>
    <dbReference type="HOGENOM" id="CLU_1816191_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0W7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="142" mass="15871" checksum="E2A1595F355153A8" modified="2011-12-14" version="1">MAAAYAAGFLTALNAVRMAYYRGNFCKLGRSPNVDCASGTATLKKARGHFGSQLTMLPRSVILNGGLVKVRKMQNLLSEKKNVSVRMLRVVKAYHSPRISVFGDALREVWHGISSRDRPRDQRAKRLGVHGFHRLASFDQRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2021-06-02" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4N134</accession>
    <name>TAS2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription factor TAS2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Tenuazonic acid biosynthesis cluster protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TAS2</name>
        <name type="ORF">MGG_07800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2017" name="ACS Chem. Biol." volume="12" first="2270" last="2274">
            <title>Regulatory mechanism of mycotoxin tenuazonic acid production in Pyricularia oryzae.</title>
            <authorList>
                <person name="Yun C.S."/>
                <person name="Motoyama T."/>
                <person name="Osada H."/>
            </authorList>
            <dbReference type="PubMed" id="28820236"/>
            <dbReference type="DOI" id="10.1021/acschembio.7b00353"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2020" name="Front. Microbiol." volume="11" first="1641" last="1641">
            <title>Mycovirus-induced tenuazonic acid production in a rice blast fungus Magnaporthe oryzae.</title>
            <authorList>
                <person name="Ninomiya A."/>
                <person name="Urayama S.I."/>
                <person name="Suo R."/>
                <person name="Itoi S."/>
                <person name="Fuji S.I."/>
                <person name="Moriyama H."/>
                <person name="Hagiwara D."/>
            </authorList>
            <dbReference type="PubMed" id="32765467"/>
            <dbReference type="DOI" id="10.3389/fmicb.2020.01641"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>INDUCTION</scope>
    </reference>
    <comment type="function">
        <text evidence="3 4">Transcription factor; part of the gene cluster that mediates the biosynthesis of the toxin tenuazonic acid (TeA), an inhibitor of protein biosynthesis on ribosomes by suppressing the release of new protein (PubMed:28820236, PubMed:32765467). Directly regulates the expression of the hybrid PKS-NRPS synthetase TAS1 and the subsequent production of TeA (PubMed:32765467).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="3 4">Expression is induced by the presence of dimethylsulphoxide (DMSO) or by the deletion of OSM1, a HOG1-related mitogen-activated protein kinase (PubMed:28820236). Expression is positively regulated by the secondary metabolism regulator LAE1 (PubMed:28820236). Infection by the totivirus induces the transcription of TAS2 (PubMed:32765467).</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="3">Impairs the ability to produce TeA under the DMSO-added, TeA-inducing culture conditions.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713017.1">
        <property type="nucleotide sequence ID" value="XM_003712969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N134"/>
    <dbReference type="STRING" id="242507.G4N134"/>
    <dbReference type="EnsemblFungi" id="MGG_07800T0">
        <property type="protein sequence ID" value="MGG_07800T0"/>
        <property type="gene ID" value="MGG_07800"/>
    </dbReference>
    <dbReference type="GeneID" id="2683727"/>
    <dbReference type="KEGG" id="mgr:MGG_07800"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07800"/>
    <dbReference type="eggNOG" id="ENOG502SJ9D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013260_2_0_1"/>
    <dbReference type="InParanoid" id="G4N134"/>
    <dbReference type="OMA" id="VVCQHEG"/>
    <dbReference type="OrthoDB" id="3014581at2759"/>
    <dbReference type="PHI-base" id="PHI:5606"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF90">
        <property type="entry name" value="CENTROMERE DNA-BINDING PROTEIN COMPLEX CBF3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000452834" description="Transcription factor TAS2">
        <location>
            <begin position="1"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Zn(2)-C6 fungal-type" evidence="1">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="28820236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="4">
        <source>
            <dbReference type="PubMed" id="32765467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="5">
        <source>
            <dbReference type="PubMed" id="28820236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="771" mass="83821" checksum="DF82D245EB6AAC53" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1E9</accession>
    <name>G4N1E9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GDS1 winged helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712227.1">
        <property type="nucleotide sequence ID" value="XM_003712179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1E9"/>
    <dbReference type="GeneID" id="2680523"/>
    <dbReference type="KEGG" id="mgr:MGG_09515"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09515"/>
    <dbReference type="eggNOG" id="ENOG502S2UH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036462_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1E9"/>
    <dbReference type="OMA" id="VGTHPKR"/>
    <dbReference type="OrthoDB" id="4150221at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057511">
        <property type="entry name" value="WH_GDS1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25318">
        <property type="entry name" value="WHD_GDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDS1 winged helix" evidence="2">
        <location>
            <begin position="137"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="446" mass="48642" checksum="04D0046A55269FEB" modified="2011-12-14" version="1">MPAYNTRKVSLSLPSLGIALPGSGGNHGQRRTTPSSATASPSSRPAPSSAPAPATSDQTSQSQARAQIPSSKKRKASNDSESQSPRPSSIAKKQQSQPTLTPVASRDPSEPTPPPSPTRSVEMADADPVVVPKPFDLDTVNDEIVEAVIRVLISQGNRPHLVKELATILMLQLRIVQQSANPCAIISSRLSSFLKRPCWSASTPCPLAKELETVHPRRTYFYLTTCPHPPFAECPVSMATPPIVKPPRAIITPSLSSGTSASEDAEDNMRRRQLSPSPEIDLSSPEFDDFDDELPSTPLGSLSSRMPPRMHHHSSRHHRGASPPLEKDEKEFTQTANVLQQRKKASGHLLATVPVDAVVETPYNSHARDENLFGGYHSHHHRTLSPVAPLPLMTFSVTSPAIRPSFGLNLKRDVEAESWARLDSMLEWDRSPENIELEELDGLLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1F8</accession>
    <name>G4N1F8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713032.1">
        <property type="nucleotide sequence ID" value="XM_003712984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1F8"/>
    <dbReference type="SMR" id="G4N1F8"/>
    <dbReference type="GeneID" id="2683743"/>
    <dbReference type="KEGG" id="mgr:MGG_07816"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07816"/>
    <dbReference type="eggNOG" id="ENOG502T1WI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108099_2_1_1"/>
    <dbReference type="InParanoid" id="G4N1F8"/>
    <dbReference type="OMA" id="WYHYKEE"/>
    <dbReference type="OrthoDB" id="5423884at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="161" mass="18061" checksum="D8AE7EC09A93BA75" modified="2011-12-14" version="1">MAPSQPLTHLLDTLVLATRTMGNDVPSPVVRRQAPATVTVISTQGGNANQQLSGGEIAGIVIGSIAGFLLIIWLIRWSCTQQRVPDEKPSYYHQEVSPGRHRSRSHGHRHHHHHRHSRSRSRGPDVRVVHSHTSAHPGGHAEPAEPTRVYYEKRRRSHSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1R9</accession>
    <name>G4N1R9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712241.1">
        <property type="nucleotide sequence ID" value="XM_003712193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1R9"/>
    <dbReference type="STRING" id="242507.G4N1R9"/>
    <dbReference type="GeneID" id="2680540"/>
    <dbReference type="KEGG" id="mgr:MGG_09503"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09503"/>
    <dbReference type="eggNOG" id="ENOG502QTEV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049945_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1R9"/>
    <dbReference type="OMA" id="HPRGWNT"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="462" mass="51888" checksum="A7EACF305B77E8E0" modified="2011-12-14" version="1">MASVARLTKDPTISCRLILLSIAVPILFILVSTFGNRVNTANNLDMARTTDPRRVAEIMLSWLNLQLVSIVELQTLWAGYGHICAVTARASNQQSAAHMRRAMGIGDGHGPQRDSDEFRLVLKFISPPMTSGDEGHWRKMLSYEVEQYFYDEVAPAVRGDAPVATCVASTRDMKGKPDAERLEGLIATLMSDLRPAYPVAGEKRTALNKTQVHAALGWLARFHRKTHELVDRDLNGFVLPPLQETERRKRNPEAAAGSKVWLNGGYTYLATRRKEYSSLARDEDSEWCDAFCAPQESASGMSVAEQVAEVLTPSGRPYETFVHGDVKSENLFTTEDGKEVAFYDFQYVGVGLGSCDLAKFFTCSVPLGMLVENRAVPDELPMGDGEMQLLKEYHQTLGLGEQYPWDLFVRHWETAMVDWCRFQASWGFWGNTDWLEARVRYILGNKSWKTWLDSQLGKTRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1V0</accession>
    <name>G4N1V0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712272.1">
        <property type="nucleotide sequence ID" value="XM_003712224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1V0"/>
    <dbReference type="GeneID" id="2680472"/>
    <dbReference type="KEGG" id="mgr:MGG_09477"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09477"/>
    <dbReference type="eggNOG" id="ENOG502SURR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_930897_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1V0"/>
    <dbReference type="OMA" id="SWVEIRP"/>
    <dbReference type="OrthoDB" id="5427732at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="299" mass="31017" checksum="A37E59AABC2D142E" modified="2011-12-14" version="1">MDASQLEAGLPTANQEKRSLAAAYSPKTAHNEPQPQHRRKMQSSRRVILAILALVLVTLGVASAVPARSWGHGPCDAQEVEGVHVQPEGGNEESGSFPCLLNAVSSEALHDVLHRYFPNRFKDGIYESDKNAMEAVHREDASLATSLVKIAKRQGGGGNNTTSAAPTTPQPPPSTTRPAPTTPTTTSAETTPTSQPPTTGPAPTTPSTRQTTPSTTAPTSTSSTTRVRSSRPVTSTFTSTASNGGLVIVTQTSFVDADPGEPTGTNPGGSLQTNAAVPRARNIAVEAFAGVLLGGLILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N203</accession>
    <name>G4N203_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SMODS and SLOG-associating 2TM effector domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713120.1">
        <property type="nucleotide sequence ID" value="XM_003713072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N203"/>
    <dbReference type="SMR" id="G4N203"/>
    <dbReference type="GeneID" id="2683807"/>
    <dbReference type="KEGG" id="mgr:MGG_07880"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07880"/>
    <dbReference type="HOGENOM" id="CLU_1219898_0_0_1"/>
    <dbReference type="InParanoid" id="G4N203"/>
    <dbReference type="OMA" id="WINAVKN"/>
    <dbReference type="OrthoDB" id="10478600at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466477" description="SMODS and SLOG-associating 2TM effector domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="24536" checksum="C68A1C68CC8AAE98" modified="2011-12-14" version="1">MRPISFALMASLLHTVVPAPTPEPMPEPMWVGPVELTPSICISLVALGVTCTNMIHNLGKTQVDNVKEAHRISMLNVEQNIGCIKNLDPGNHVATELQRKVRDIRDSTAQAGRYSSGPPLLPYKGKLVAAYEQHCDELMRLNEQAKSELNRLQGHSSPRGSHDAELGRPSSSDYLTPQTSLSSNPGSGRNGGSKEGGWINAVKNGGSFTWPGTGSRKHSDGLLPQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N241</accession>
    <name>G4N241_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Isotrichodermin C-15 hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_07550</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711464.1">
        <property type="nucleotide sequence ID" value="XM_003711416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N241"/>
    <dbReference type="SMR" id="G4N241"/>
    <dbReference type="STRING" id="242507.G4N241"/>
    <dbReference type="GeneID" id="2683470"/>
    <dbReference type="KEGG" id="mgr:MGG_07550"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07550"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="InParanoid" id="G4N241"/>
    <dbReference type="OMA" id="ICETAVM"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF29">
        <property type="entry name" value="BENZOATE-PARA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA51657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="495" mass="56339" checksum="DA003C0318C2A397" modified="2011-12-14" version="1">MIIPTSWREALLYLGLGVVAIFACNAVYNVFFHPLRHFPGPKSHAMSRIPYTYHWVRGDLVRHITALHREHGDIVRLAPDELSFGDPQAWGDIMGGGSRDLQKWNGVFDIPNFLPTHVQNTTDKSRHRMLRKAMGPGFSDAALRAQEHIVASHVDQFIQKLRGRRGVVDLEVWYRFIVFDVIGDLAFGESFGCANGAEFHPYIRQICETAVMISYLMAINMYPILRNVVNFLIDGVARRGFDAQAQTLMPALERRIKLQEQRLDLVDPLIGKMNEWKWTINDLIPHAIMIVGAGSETTAGVLCGTTALLLEHPEAMARVTEEVRSAFSSDGEINLERVDSRLPYLRACIDEAMRLYPVPGCASLRITGDRDIICGVPMPPKTVVGLWPYAVYRDPKLWRNPDEFHPERWLGDPEYINDARKAFNPFHIGSRDCVGRGLAVMELRLIMARMIYNFDMHLMGAGMKEDSRSWVDRQKNFFIVWERVPLEVVLTPTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2H9</accession>
    <name>G4N2H9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Intradiol ring-cleavage dioxygenases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711495.1">
        <property type="nucleotide sequence ID" value="XM_003711447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2H9"/>
    <dbReference type="SMR" id="G4N2H9"/>
    <dbReference type="GeneID" id="12987068"/>
    <dbReference type="KEGG" id="mgr:MGG_15211"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15211"/>
    <dbReference type="eggNOG" id="ENOG502QPRK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027719_0_1_1"/>
    <dbReference type="InParanoid" id="G4N2H9"/>
    <dbReference type="OMA" id="FMMGANG"/>
    <dbReference type="OrthoDB" id="121380at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03457">
        <property type="entry name" value="intradiol_dioxygenase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34315:SF1">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466012" description="Intradiol ring-cleavage dioxygenases domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="39671" checksum="852F50BC43056832" modified="2011-12-14" version="1">MGFKTSLAAALLAIPQGLAHPHPVDEPEYQHHARPLMERSLDHCAGQFAEPEFMKRTIDRHSDEYDRLRRALGVEPEGSPHISKRDYISVSRIDHKSNKPVSKGMDLSSLFTDYGACMLMPAVDQGPLYVKGEEVRKDITNGEKGIPMTLAIQVVDYQTCKVLPDAYVDIWSSNATGMYVGVQGYPGMGDPKDASILKGTTLRGVQPTDKAGVASFDTLMPAIVYLGATKLQNNTLSGGRAAHVGQLYFDQSLVTASSQAAPYNTNRMATTLNVRDFLFMQGANGDDPIVRYALVGDRLEDGLFAWIRFGVRGNANLPVNPAAFWTANGGVMNPTGPISKIGGGFGGWPGGKNKARAVAEAVADRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2M4</accession>
    <name>G4N2M4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Riboflavin kinase</fullName>
            <ecNumber evidence="4">2.7.1.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Flavin mononucleotide kinase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_07618</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>riboflavin + ATP = FMN + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="4"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711540.1">
        <property type="nucleotide sequence ID" value="XM_003711492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2M4"/>
    <dbReference type="SMR" id="G4N2M4"/>
    <dbReference type="STRING" id="242507.G4N2M4"/>
    <dbReference type="GeneID" id="2683538"/>
    <dbReference type="KEGG" id="mgr:MGG_07618"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07618"/>
    <dbReference type="eggNOG" id="KOG3110">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022880_1_0_1"/>
    <dbReference type="InParanoid" id="G4N2M4"/>
    <dbReference type="OMA" id="FQLVLCQ"/>
    <dbReference type="OrthoDB" id="276388at2759"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="10 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Riboflavin kinase" evidence="15">
        <location>
            <begin position="503"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="137"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA51733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="722" mass="78200" checksum="448ED1D9A2066CE8" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N333</accession>
    <name>G4N333_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase, mitochondrial</fullName>
            <ecNumber evidence="6">2.7.7.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">CDP-diacylglycerol synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MGG_04909</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAM41 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712396.1">
        <property type="nucleotide sequence ID" value="XM_003712348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N333"/>
    <dbReference type="SMR" id="G4N333"/>
    <dbReference type="STRING" id="242507.G4N333"/>
    <dbReference type="GeneID" id="2675322"/>
    <dbReference type="KEGG" id="mgr:MGG_04909"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04909"/>
    <dbReference type="eggNOG" id="KOG2986">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030279_0_0_1"/>
    <dbReference type="InParanoid" id="G4N333"/>
    <dbReference type="OMA" id="KQTVNWP"/>
    <dbReference type="OrthoDB" id="341477at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015222">
        <property type="entry name" value="Tam41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13619">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13619:SF0">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09139">
        <property type="entry name" value="Tam41_Mmp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="17" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="43"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="493"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="524"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EHA52589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="537" mass="60711" checksum="639AE0DE12390F1A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N373</accession>
    <name>G4N373_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphotyrosine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_04942</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712436.1">
        <property type="nucleotide sequence ID" value="XM_003712388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N373"/>
    <dbReference type="SMR" id="G4N373"/>
    <dbReference type="FunCoup" id="G4N373">
        <property type="interactions" value="584"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N373"/>
    <dbReference type="GeneID" id="2675516"/>
    <dbReference type="KEGG" id="mgr:MGG_04942"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04942"/>
    <dbReference type="eggNOG" id="KOG3217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071415_2_0_1"/>
    <dbReference type="InParanoid" id="G4N373"/>
    <dbReference type="OMA" id="VCHGNIC"/>
    <dbReference type="OrthoDB" id="3388at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004726">
        <property type="term" value="F:non-membrane spanning protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16343">
        <property type="entry name" value="LMWPTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000105">
        <property type="entry name" value="Low molecular weight phosphotyrosine protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050438">
        <property type="entry name" value="LMW_PTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002115">
        <property type="entry name" value="Tyr_Pase_low_mol_wt_mml"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717:SF7">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00720">
        <property type="entry name" value="MAMMALPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="Phosphotyrosine protein phosphatases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphotyrosine protein phosphatase I" evidence="10">
        <location>
            <begin position="46"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR617867-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA52629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="209" mass="23268" checksum="77551E1ACB439F64" modified="2011-12-14" version="1">MRRTNNDRATPSPRSGAFARMPVRLPTTSSTPPTPTSTESTMPEKVSVLFCCLGNICRSTMAEGVFRDMTGKAPYKDRVGRVDSCGTGAYHTGDSPDDRTMATLEAHGITDYQHAARKVSLKDFDTFDYIFAMDRSNLSDLERLKRSKPDAKAKVMLFGEFSGTGKAEIVSDPYYGGHQGFEKAYEQAMRFSKNFLKDKFPEVEVESEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3E3</accession>
    <name>G4N3E3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_07684</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711628.1">
        <property type="nucleotide sequence ID" value="XM_003711580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3E3"/>
    <dbReference type="GeneID" id="2683604"/>
    <dbReference type="KEGG" id="mgr:MGG_07684"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07684"/>
    <dbReference type="eggNOG" id="ENOG502TEVA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_980302_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3E3"/>
    <dbReference type="OMA" id="SQMAYYL"/>
    <dbReference type="OrthoDB" id="5213764at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466065" evidence="3">
        <location>
            <begin position="18"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="284" mass="29849" checksum="46348A5BAC827FDB" modified="2011-12-14" version="1">MWLGAVLLLALGATAGAQDRSGEHVALCDCKNDAELVSSQMAYYLGVPDSTPVDVATVPNTPNGQARVWPSATTSALFTLTNVTFTAKLGPQVEVGAFAGTGSNGWPSPFNCWFTPSQKLYVYDGWTCAMVYDCSHDAANSTTPSTPSGAPTSRPTRAPNQPSDSSGISTPALIGVAVGSGVVAIIVIGAIGFVCVQRRRARDATRQMEERRSQSPPKSPCGGVFDAEGRWHQTIKPGPPQEMDGQYRGLEIHAGPTGGYREIDSTAVAAEVAGNRTHGSFYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3Q6</accession>
    <name>G4N3Q6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_13290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711687.1">
        <property type="nucleotide sequence ID" value="XM_003711639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3Q6"/>
    <dbReference type="SMR" id="G4N3Q6"/>
    <dbReference type="STRING" id="242507.G4N3Q6"/>
    <dbReference type="ESTHER" id="mago7-a4qwz1">
        <property type="family name" value="Haloacetate_dehalogenase"/>
    </dbReference>
    <dbReference type="GeneID" id="5049145"/>
    <dbReference type="KEGG" id="mgr:MGG_13290"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13290"/>
    <dbReference type="eggNOG" id="ENOG502S6U1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_7_1_1"/>
    <dbReference type="InParanoid" id="G4N3Q6"/>
    <dbReference type="OMA" id="RGARICH"/>
    <dbReference type="OrthoDB" id="6431331at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="41"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="322" mass="34468" checksum="78A5DED59F0E887E" modified="2011-12-14" version="1">MAADPKNFYPALKRSTTPTASGSDVVAYTSDAGPGRPILTLIHGYPQSSLIWRHIVPELIGKVSLFIPELPGYGISTPPNSHTKLDVGRALLESLRAAFAIDKSSSRGLIVGGHDRGARVAHRLAASQDALFPADGGLSLLGAVLLDIVPTKVQWEAFADPAVSRGYFHWPLLANVALAVPVLQAYGGARWCRGSHALIAGSNEAGRARIAADGAIDVHAGFFESEEVLRATCEDYAAGSNEDVVEQVRDQKAGRKITVPTLVMFSAEKLGARLDVAEIWRDWIAEGVDYTPVAVGDGYGHYLPEEASDVVAQKINEFLDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3X5</accession>
    <name>G4N3X5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="KEGG" id="mgr:MGG_15242"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15242"/>
    <dbReference type="eggNOG" id="ENOG502RS9E">
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    <dbReference type="OrthoDB" id="2157530at2759"/>
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        <property type="entry name" value="HetReg/Transcr_Mod"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
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        <property type="entry name" value="HET"/>
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        <property type="entry name" value="Het-6_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="248"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF06985"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA51897.1"/>
        </source>
    </evidence>
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        <source>
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            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
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        <name evidence="4" type="ORF">MGG_05955</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711793.1">
        <property type="nucleotide sequence ID" value="XM_003711745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4B8"/>
    <dbReference type="GeneID" id="2684020"/>
    <dbReference type="KEGG" id="mgr:MGG_05955"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05955"/>
    <dbReference type="eggNOG" id="ENOG502QQV3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036323_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4B8"/>
    <dbReference type="OMA" id="MMDASLE"/>
    <dbReference type="OrthoDB" id="5560627at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
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        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
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        <location>
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        <location>
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        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50157"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA51986.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4C5</accession>
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        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
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            <taxon>Sordariomycetes</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA51993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003711752.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_16724"/>
    <dbReference type="HOGENOM" id="CLU_1796851_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4C5"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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        </location>
    </feature>
    <feature type="chain" id="PRO_5003466105" description="Extracellular membrane protein CFEM domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="14979" checksum="E7F61165B45CD445" modified="2011-12-14" version="1">MLIVTISESVVSFFSFVAVLQAESSGKRTYKRRAHPLNHTVSCLSAQATRSTRASTELKTSKRPANEPDTAANMQFILTLATLLAAASASPVAAPAAAPVYARAAAAPCKNLDKYLECAAQGCHPSIPAGVCAAPATCAIIWCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4S8</accession>
    <name>G4N4S8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Meiotic sister chromatid recombination protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
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                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
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                <person name="Young S.K."/>
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                <person name="Arachchi H.M."/>
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                <person name="Dunbar C."/>
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                <person name="Gearin G."/>
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                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
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                <person name="MacDonald P.J.P."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
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                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
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                <person name="Dunbar C."/>
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                <person name="Griggs A."/>
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                <person name="Heiman D."/>
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                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Shea T."/>
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                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="293" mass="33047" checksum="979FCA072334275C" modified="2011-12-14" version="1">MLLSLIQTHMSYLFIKTNFIGVRAQFIREHDPKPGRRWNYAVQVLYNPILPLVKASILVTLILPGSEGRVGLGPLFRGKSRYQLPDAETGMTDNKSGKKGRSRGGIRKQRPIQSRDVRVLRINDATSPSLTEDKKTDLRGRSPRRRRRRSAENTMTSANGIMRLSDVQREIDVLVKDLAVGPGGSYLLKRPTGHDERERQEQFRREMEQMEREVRSRQQAAAAPRKPPSEANFSSYAAGVVSCASSQAGPRIGPRTRSRTRNRDFSEARKPKHGDKRNGVIPPSEPTAPAWPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N807</accession>
    <name>G4N807_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_03494</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716428.1">
        <property type="nucleotide sequence ID" value="XM_003716380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N807"/>
    <dbReference type="SMR" id="G4N807"/>
    <dbReference type="STRING" id="242507.G4N807"/>
    <dbReference type="GeneID" id="2676688"/>
    <dbReference type="KEGG" id="mgr:MGG_03494"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03494"/>
    <dbReference type="eggNOG" id="KOG1404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_4_0_1"/>
    <dbReference type="InParanoid" id="G4N807"/>
    <dbReference type="OMA" id="YQNFPKT"/>
    <dbReference type="OrthoDB" id="5419315at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000004">
        <property type="entry name" value="Acetylornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005685">
        <property type="entry name" value="PRK07483.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43094:SF1">
        <property type="entry name" value="AMINOTRANSFERASE CLASS-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA50109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="460" mass="49884" checksum="34F2F65CB0F8601B" modified="2011-12-14" version="1">MATTKSAFLHRSLKEFPAQVVEAKDKTLVFSDGTKVLDSTCGAAVACIGYNNDLSERVKQAMIRQMDKFPYCNSFFGHEVGEQLAQELMDGTGGAMSKAYIVNSGSEAMEGTMKMARQYFLELQPPQPSRINFIAREGSYHGTTLGALSMSGHVGRRSKFLDLLLPNVARVSRCDAYRGMKEGQSVAEYVEQLADELDKKFQELGPETVCAFVAEPVVGATLGCVPAVPGYFEAMRKVCDKYGALLILDEVMSGMGRSGTLHAWQQEGVVPDIQTIGKGLGGGYAPVAAFMINHRVADTLESGTGEFMHGHTYQGHALGCAAALEVQRIVREENLIDNVKQRGVQLEKLLQQHLGNHPNVGNIRGKGLFWGIEFVADKASKEPFPRSVDLANKVNRAGVKEFGVSLYPGTGTKDGVLGDHVILAPAYNCTADEIEEIVIKTKETVARVLRVKNAETATSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N884</accession>
    <name>G4N884_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716450.1">
        <property type="nucleotide sequence ID" value="XM_003716402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N884"/>
    <dbReference type="GeneID" id="2676823"/>
    <dbReference type="KEGG" id="mgr:MGG_03474"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03474"/>
    <dbReference type="eggNOG" id="ENOG502RHP9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067171_0_0_1"/>
    <dbReference type="InParanoid" id="G4N884"/>
    <dbReference type="OMA" id="WEGDELH"/>
    <dbReference type="OrthoDB" id="4359806at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465918" evidence="1">
        <location>
            <begin position="26"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="318" mass="36329" checksum="7E53DC45E10DBD25" modified="2011-12-14" version="1">MFSHPIPQALGPLLVLLYLSSPALAWDHLDRKHPTHRTLSTFRWTRPFLDLELKAENPHADPKDLDRDIPGGFHVYCEATKTFAARQLTAADLHKPPPDGLEPWAAALDVALHQRVYPGGWDGEELIGDGMQVLVMEYSDVPPTVRRFVEQEGVDAHTAKRWQFGVYDKPGRAGKQRRVAFGEGSSYVEDRPTAPQDKVMIFAPGALYDILPLWVADDSACKKQFQDLDKYVKHAEHNRVIAWPMTHTEPDPAPGGRKTIFFQIRASLLLETVQGRRHREAWKNVHLQASRAERRLQRDERKKGKGRRRVDAIWHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8C8</accession>
    <name>G4N8C8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716494.1">
        <property type="nucleotide sequence ID" value="XM_003716446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8C8"/>
    <dbReference type="GeneID" id="12984482"/>
    <dbReference type="KEGG" id="mgr:MGG_17095"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17095"/>
    <dbReference type="HOGENOM" id="CLU_1970982_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8C8"/>
    <dbReference type="OrthoDB" id="10543357at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="127" mass="13708" checksum="AE194E55806DBE5B" modified="2011-12-14" version="1">MSELPTWKAPARLDQLNSGAGGEPHSLLDICESGQVKVPPRLAASGGMHTIHPESSFSGSAHHRARFSCSLWPERTLSGFTKFGKSDPSTAECGRQPQNFEFTPPNGFSDGLNSIECPSRRQRSAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8N8</accession>
    <name>G4N8N8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Benzoate 4-monooxygenase cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03392</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716551.1">
        <property type="nucleotide sequence ID" value="XM_003716503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8N8"/>
    <dbReference type="SMR" id="G4N8N8"/>
    <dbReference type="STRING" id="242507.G4N8N8"/>
    <dbReference type="GeneID" id="2676883"/>
    <dbReference type="KEGG" id="mgr:MGG_03392"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03392"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="InParanoid" id="G4N8N8"/>
    <dbReference type="OMA" id="DPPRDCT"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF168">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="56542" checksum="8BE604A2204474FF" modified="2011-12-14" version="1">MSFSAGSSSSCAMLATAAIWGISAVVAYAVFARFRDWRRLKHIDGPSLAGWTDYWMIRSQLSGRMNLDLADVVREYGPVARIGTNTIVCADVKELRKIWAVRSTWKRPRWYLGLRIDPYSDNVFSLMDDKVHETLRSKLMPGYGGKDVDGVHEIIDEQISLFVRLLEDKYLSVDGKDSEGKSFLPVDLARKVQFLTLDIISSLAFGESFGNLVADDDALGYISTTEKSMPMLMFVTLVPWLTAVWQSPRLRWAFPDARKMVGIGDVMAIARRVVGERYGEKPEVVKRDMLGSFVAHGLTKGEAESETMVQIVAGSDTSATAIRSTLLFIITNPAVYSRLQAEIDAAAAEGRISSPITDAEARALPYLQAVIREGLRMYPPATGLLPKVSSKDEILCGKHIPAGTDVGWAVWPVMRDRGVFGDDADLFRPERWVEAAPEQWRVMDQTVMMDFATGSRWECLGKTIAMIELNKAYVEVCPALIDCLSKWESSLISALTQTSRTRRLPQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8W5</accession>
    <name>G4N8W5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dynactin arp1 p25 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716579.1">
        <property type="nucleotide sequence ID" value="XM_003716531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8W5"/>
    <dbReference type="GeneID" id="2676643"/>
    <dbReference type="KEGG" id="mgr:MGG_03368"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03368"/>
    <dbReference type="eggNOG" id="ENOG502SRM6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099929_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8W5"/>
    <dbReference type="OMA" id="CLKCALT"/>
    <dbReference type="OrthoDB" id="2587363at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465940" description="Dynactin arp1 p25 subunit" evidence="2">
        <location>
            <begin position="20"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="23686" checksum="D4A3A229224B9683" modified="2011-12-14" version="1">MVSVRYLVGAALAIASVSASVLEPEDLLEQASRLLKRQEPGTPAYNCHNTCGQALRQGRFSGDARCSNDVFLTNYKNCLQCSGPDNHNIWTFYGNSVGSFGRACGLSTTPLSGKQPDVPEAIPAVDPGAAVTSATASSAAASSTGPRVTATPPAAPSSTSGASSAATTSPVSVPSSASASAGGGSATRTTASASGGASVGGGGSSTSRANAPTSAPVPAGAAAVAKNMASLAVAVVAVGARLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAF0</accession>
    <name>G4NAF0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716814.1">
        <property type="nucleotide sequence ID" value="XM_003716766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAF0"/>
    <dbReference type="STRING" id="242507.G4NAF0"/>
    <dbReference type="GeneID" id="2677028"/>
    <dbReference type="KEGG" id="mgr:MGG_03176"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03176"/>
    <dbReference type="eggNOG" id="ENOG502RNMU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1496300_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAF0"/>
    <dbReference type="OMA" id="NWLANVD"/>
    <dbReference type="OrthoDB" id="5231339at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="179" mass="19443" checksum="955534C647CCFECD" modified="2011-12-14" version="1">MPGAWNAEAERDLILASWAGTSTGPVRPDWPKTIAIMNAWGYDFSGEALKSRGSKTILKDFKSKQETAIATIAGNAHVGLKASPAKRKAKAANSGDSPVKKSRSTPKTTVKTETFDEVANTYLQDSIEGDDTEDNEGDNEDTASPLPHRRNPRRSVSQPHTYKEEKLEGERGEDSDSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB45</accession>
    <name>G4NB45_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">alpha-D-xyloside xylohydrolase</fullName>
            <ecNumber evidence="5">3.2.1.177</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_11536</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.</text>
            <dbReference type="EC" id="3.2.1.177"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.177" evidence="5"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718391.1">
        <property type="nucleotide sequence ID" value="XM_003718343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB45"/>
    <dbReference type="SMR" id="G4NB45"/>
    <dbReference type="STRING" id="242507.G4NB45"/>
    <dbReference type="GeneID" id="5050692"/>
    <dbReference type="KEGG" id="mgr:MGG_11536"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11536"/>
    <dbReference type="eggNOG" id="KOG1066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_10_0_1"/>
    <dbReference type="InParanoid" id="G4NB45"/>
    <dbReference type="OMA" id="QGVDCFK"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061634">
        <property type="term" value="F:alpha-D-xyloside xylohydrolase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06593">
        <property type="entry name" value="GH31_xylosidase_YicI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000053">
        <property type="entry name" value="Alpha-xylosidase YicI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007940">
        <property type="entry name" value="PRK10658.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF4">
        <property type="entry name" value="MYOGENESIS-REGULATING GLYCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="9">
        <location>
            <begin position="55"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="8">
        <location>
            <begin position="281"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="10">
        <location>
            <begin position="617"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="86"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00052064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00066962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA48807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="789" mass="88721" checksum="64151FDEFA10B032" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBD3</accession>
    <name>G4NBD3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_14388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717676.1">
        <property type="nucleotide sequence ID" value="XM_003717628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBD3"/>
    <dbReference type="SMR" id="G4NBD3"/>
    <dbReference type="GeneID" id="2676242"/>
    <dbReference type="KEGG" id="mgr:MGG_14388"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14388"/>
    <dbReference type="eggNOG" id="ENOG502RMBG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1397304_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBD3"/>
    <dbReference type="OMA" id="QHTANMN"/>
    <dbReference type="OrthoDB" id="4751730at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466411" evidence="2">
        <location>
            <begin position="19"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="201" mass="21253" checksum="73D0D7D656FBB755" modified="2011-12-14" version="1">MKFSFVATLAMAVSVMSAAVPAMPQPIGTVMVMEKRQFESNGAILDTLKQAVVEQTTQINATLDGAPESPSTDEANSLADEINPRFAAIADALREATSSFQLRSLVARQEEDGEADSCDAQCITEKVLDIVYEIASTIRAAIERLGLRPLILQINPLLLALSALVISLNVLISGLLLTVSAVVTTLLGGLGLSLLLLGFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBF1</accession>
    <name>G4NBF1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718492.1">
        <property type="nucleotide sequence ID" value="XM_003718444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBF1"/>
    <dbReference type="GeneID" id="12984102"/>
    <dbReference type="KEGG" id="mgr:MGG_17428"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17428"/>
    <dbReference type="HOGENOM" id="CLU_1993064_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBF1"/>
    <dbReference type="OrthoDB" id="10476055at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="125" mass="14006" checksum="65C97F09815B10C2" modified="2011-12-14" version="1">MTNKGEYSGRCTTTQNLREYSQQGSRQQFRGTSFCMSCNKWLVSIPHDPKQLVFVEFLAVHILAARPGAELNLLRQVCPGRRITADSGFVFRVAQPILPALLLEYSSPAATEIDPIFSDGVRFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBJ8</accession>
    <name>G4NBJ8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717687.1">
        <property type="nucleotide sequence ID" value="XM_003717639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBJ8"/>
    <dbReference type="SMR" id="G4NBJ8"/>
    <dbReference type="GeneID" id="2675270"/>
    <dbReference type="KEGG" id="mgr:MGG_11003"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11003"/>
    <dbReference type="HOGENOM" id="CLU_2527917_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBJ8"/>
    <dbReference type="OrthoDB" id="4226417at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="84" mass="9630" checksum="6B3676928F31C8B9" modified="2011-12-14" version="1">MYLVYELVEHTLQDLVRSQHSLEVKELGAIVKQILEGLIYLEVNGIGLLDLECADIRFRPNGCLQIGSFNLRAWTEDQIKLRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBP2</accession>
    <name>G4NBP2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_00522</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNAP-25 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718534.1">
        <property type="nucleotide sequence ID" value="XM_003718486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBP2"/>
    <dbReference type="SMR" id="G4NBP2"/>
    <dbReference type="FunCoup" id="G4NBP2">
        <property type="interactions" value="115"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NBP2"/>
    <dbReference type="GeneID" id="2674564"/>
    <dbReference type="KEGG" id="mgr:MGG_00522"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00522"/>
    <dbReference type="eggNOG" id="KOG3065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020823_2_0_1"/>
    <dbReference type="InParanoid" id="G4NBP2"/>
    <dbReference type="OMA" id="TNQRMER"/>
    <dbReference type="OrthoDB" id="18679at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305">
        <property type="entry name" value="SYNAPTOSOMAL ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305:SF9">
        <property type="entry name" value="SYNAPTOSOMAL-ASSOCIATED PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="4">
        <location>
            <begin position="408"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="254"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="65"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="449"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA48950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="464" mass="50439" checksum="1B64AAEB2F3518C1" modified="2011-12-14" version="1">MKKFLGRKDKSPKPPTDNPYAQEPANDPYAAYPNAAPKSQVRAPGGLPAGPGGGLPSGPRGGLPSGPARGNSMNSVNSMSSTSTAPPPYQSQQQQPPQQSSGYGNERYGASGGYGSSNRYGNDNSGGGGGGYDSSAGRRGPGGYGGLGRTDTMDDQAGKEALFGGGKERVQNAPRGPNGNAGGYGASAGGYGAGNQGSTGNKYGGYGEDRELTEEERIKLEERDLARQIDQERDATVDTGHRILGIINSTIETANGTMQNMAQQDERLRNTERNLDLARIHNRTAEERTKELKHYNRSLWNPGNPFMSKSKQEQRERKHLENTQKDRELREATRADAYESQAQYERDLKDIETNMANRRALGLSSSEKAASNNKFVFDESDEEDDNPENMALRADRRAKEDEINNSIMPQMEAGVATLNRIARNFAPRIEESNQLIGRLQTKSDGVSDGVERNKQQLDRIYKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBQ2</accession>
    <name>G4NBQ2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Conidiation-specific protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718544.1">
        <property type="nucleotide sequence ID" value="XM_003718496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBQ2"/>
    <dbReference type="GeneID" id="2674755"/>
    <dbReference type="KEGG" id="mgr:MGG_00513"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00513"/>
    <dbReference type="eggNOG" id="ENOG502T0UQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_180967_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBQ2"/>
    <dbReference type="OMA" id="DQKRHEG"/>
    <dbReference type="OrthoDB" id="4158609at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9052" checksum="6BB05F26A6E3B456" modified="2011-12-14" version="1">MDSSAANATRERSNSTSSSSSAGNSPISPKPRRNSAGLFASLEQTKRPTDPASIARRQSLHEQRPTPGLFGKMWNTWVRGVPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND46</accession>
    <name>G4ND46_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">U3 small nucleolar ribonucleoprotein protein IMP4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717972.1">
        <property type="nucleotide sequence ID" value="XM_003717924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND46"/>
    <dbReference type="SMR" id="G4ND46"/>
    <dbReference type="FunCoup" id="G4ND46">
        <property type="interactions" value="888"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ND46"/>
    <dbReference type="GeneID" id="2674209"/>
    <dbReference type="KEGG" id="mgr:MGG_00977"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00977"/>
    <dbReference type="eggNOG" id="KOG2781">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040063_2_0_1"/>
    <dbReference type="InParanoid" id="G4ND46"/>
    <dbReference type="OMA" id="IGTMSEQ"/>
    <dbReference type="OrthoDB" id="10253204at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140691">
        <property type="term" value="F:RNA folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000001">
        <property type="entry name" value="IMP4, U3 small nucleolar ribonucleoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF2">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="83"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00040513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="295" mass="33712" checksum="DF9F50DCEF619683" modified="2011-12-14" version="1">MIRKQARERRDYLYRKVAILKDAEINEKKAKMRASLAQGRPLEKDIANDEKLRADYHYDESRIDREDLDLDDEYAQLSGLVDPRVMVTTSRDPSARLAAFAKEIRLLLPTAIRLNRGNLILPELVRSVQAAGLSDIVLLHERRGTPTALTISHMPHGPTVSFSLHNVLLRHDIPGSVRGTVSEAYPHLVFDGFTSKLGQRIVKVLKHLFPPREPITNKAKMSNRVITFKNIDDVIEVRHHVFVRTGHESVELAEVGPRMSMKVFEIRGGTLENKDGDVEWHLSQYTRTSRKKNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE40</accession>
    <name>G4NE40_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoprotease pgp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718953.1">
        <property type="nucleotide sequence ID" value="XM_003718905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE40"/>
    <dbReference type="SMR" id="G4NE40"/>
    <dbReference type="FunCoup" id="G4NE40">
        <property type="interactions" value="415"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NE40"/>
    <dbReference type="GeneID" id="2674465"/>
    <dbReference type="KEGG" id="mgr:MGG_00172"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00172"/>
    <dbReference type="eggNOG" id="KOG2707">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023208_4_0_1"/>
    <dbReference type="InParanoid" id="G4NE40"/>
    <dbReference type="OMA" id="NAAMIGC"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072670">
        <property type="term" value="P:mitochondrial tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gcp-like" evidence="2">
        <location>
            <begin position="165"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Gcp-like" evidence="2">
        <location>
            <begin position="399"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="596" mass="65830" checksum="B39B155873F0217B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEQ0</accession>
    <name>G4NEQ0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein PhiA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719057.1">
        <property type="nucleotide sequence ID" value="XM_003719009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEQ0"/>
    <dbReference type="GeneID" id="2675049"/>
    <dbReference type="KEGG" id="mgr:MGG_00081"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00081"/>
    <dbReference type="eggNOG" id="ENOG502SRG4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097238_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEQ0"/>
    <dbReference type="OMA" id="WSIWADA"/>
    <dbReference type="OrthoDB" id="4093325at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466144" description="Cell wall protein PhiA" evidence="1">
        <location>
            <begin position="19"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="19654" checksum="6FD2B881A6CC6451" modified="2011-12-14" version="1">MQFTVASVLSVLAATAAALPASSNSSAIPDGTKFNLLSLRSASPVHFAYFQAAHRGLLVKLPEQGANCTGGNDISNNLATFYIKDKGLYLYGPDGCETQQIFTDLSGMGQGVIQYTTGDQGLPRNAQRGPFTIDADGNLRVADFGFVACPSFNQSYSIRAGGGGSDDCLGISARVVPAADPGACVYSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEX2</accession>
    <name>G4NEX2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718282.1">
        <property type="nucleotide sequence ID" value="XM_003718234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEX2"/>
    <dbReference type="GeneID" id="12984057"/>
    <dbReference type="KEGG" id="mgr:MGG_17387"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17387"/>
    <dbReference type="HOGENOM" id="CLU_2171568_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEX2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466543" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="11385" checksum="9265B7EB05E85A06" modified="2011-12-14" version="1">MAPFFFFFFSIIAAPVLHPPAPKETHGYCRVLVGSLLAASGSLSAGGPAIGTTYAQCYCTQLVLTGSGCGNDTLGSGRPSRLGSRHPVGVDQKDFVLFADAIESPPAPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF99</accession>
    <name>G4NF99_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04177</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719648.1">
        <property type="nucleotide sequence ID" value="XM_003719600.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NF99"/>
    <dbReference type="STRING" id="242507.G4NF99"/>
    <dbReference type="GeneID" id="2677686"/>
    <dbReference type="KEGG" id="mgr:MGG_04177"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04177"/>
    <dbReference type="eggNOG" id="ENOG502QVYS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001569_0_1_1"/>
    <dbReference type="InParanoid" id="G4NF99"/>
    <dbReference type="OMA" id="MQKVMTF"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1871" mass="202015" checksum="16688C74B0375431" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFT9</accession>
    <name>G4NFT9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719263.1">
        <property type="nucleotide sequence ID" value="XM_003719215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFT9"/>
    <dbReference type="GeneID" id="12985743"/>
    <dbReference type="KEGG" id="mgr:MGG_17580"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17580"/>
    <dbReference type="HOGENOM" id="CLU_2027186_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFT9"/>
    <dbReference type="OrthoDB" id="5234600at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466483" evidence="1">
        <location>
            <begin position="19"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="122" mass="13113" checksum="16DE7E9DEF49ABFA" modified="2011-12-14" version="1">MQFFTLTLALFTLRFTTAEPIPANVGLLSEAVADGPMVARVILMSASEALTPCCQVHFRGNCDCGSCPIASCSSFDRRYWGRLASTLKEFDPCLALLPTYKAKSSQVPGGRDPTFGPFAAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFV7</accession>
    <name>G4NFV7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719281.1">
        <property type="nucleotide sequence ID" value="XM_003719233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFV7"/>
    <dbReference type="SMR" id="G4NFV7"/>
    <dbReference type="STRING" id="242507.G4NFV7"/>
    <dbReference type="GeneID" id="2678948"/>
    <dbReference type="KEGG" id="mgr:MGG_08699"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08699"/>
    <dbReference type="eggNOG" id="ENOG502S8JU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067850_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFV7"/>
    <dbReference type="OMA" id="EHQDYVW"/>
    <dbReference type="OrthoDB" id="276276at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd02883">
        <property type="entry name" value="NUDIX_Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736">
        <property type="entry name" value="ADP-RIBOSE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43736:SF1">
        <property type="entry name" value="DIHYDRONEOPTERIN TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="52"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="218" mass="23193" checksum="9D0A9AAD9589F280" modified="2011-12-14" version="1">MPPAPGTQPPAHPDSPVYNFTISDPDTAATFNVPASAVIAARKAANPAKVTYSALGTGAVVFNRARTAVLLVQRSVGDSMPNLWEVPGGGVDDSDATVVHAVARELWEEAGLTARRIGAVVPAAEGGPAEFVFATRSGRIVAKFHFLIEADGDGDDVRLDPNEHQACVWATEEECVDEKMRSGLEIPFTTKSQKATVLQAWRMMREGRDGLGSAEHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG01</accession>
    <name>G4NG01_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7907 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719325.1">
        <property type="nucleotide sequence ID" value="XM_003719277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG01"/>
    <dbReference type="STRING" id="242507.G4NG01"/>
    <dbReference type="GeneID" id="2681159"/>
    <dbReference type="KEGG" id="mgr:MGG_01944"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01944"/>
    <dbReference type="eggNOG" id="ENOG502RJN7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102302_0_0_1"/>
    <dbReference type="InParanoid" id="G4NG01"/>
    <dbReference type="OMA" id="VASINWS"/>
    <dbReference type="OrthoDB" id="3518533at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057229">
        <property type="entry name" value="DUF7907"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25484">
        <property type="entry name" value="DUF7907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466253" description="DUF7907 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7907" evidence="2">
        <location>
            <begin position="31"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="230" mass="25440" checksum="EFD0229C40F1E908" modified="2011-12-14" version="1">MLTKSILLATLAALAAANPIARRSGPETSRSRGWKLIANVTESPITGFGAEINHFQVTGIHIGPPYNRAVLYEQYEGGGSRIFYTNGSTEQGGTSQVLTDSNGFSPHFHMQRPDEFDLPANDKSHATFLQPGPDAGDDVVLEGKKLVSRFGAGKFVACKHWVQYYQSLWNVVDYVYEGEETPEGCVDINLLAQCDELKPIEENTEWNWFSHAHVVEEECYVDVAGADWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH92</accession>
    <name>G4NH92_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-oxo-5-alpha-steroid 4-dehydrogenase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03905</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719969.1">
        <property type="nucleotide sequence ID" value="XM_003719921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH92"/>
    <dbReference type="SMR" id="G4NH92"/>
    <dbReference type="STRING" id="242507.G4NH92"/>
    <dbReference type="GeneID" id="2677199"/>
    <dbReference type="KEGG" id="mgr:MGG_03905"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03905"/>
    <dbReference type="eggNOG" id="KOG1638">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065395_0_0_1"/>
    <dbReference type="InParanoid" id="G4NH92"/>
    <dbReference type="OMA" id="PHYALEW"/>
    <dbReference type="OrthoDB" id="5788137at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016636">
        <property type="entry name" value="3-oxo-5-alpha-steroid_4-DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF43">
        <property type="entry name" value="STEROID 5-ALPHA-REDUCTASE DET2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015596">
        <property type="entry name" value="5_alpha-SR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="115"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="291" mass="33821" checksum="A3AC5DDB40B9C607" modified="2011-12-14" version="1">MAIIENWIPPTRENWETLLFVWKFFPILPSVQWLTPWYPMGKTSYPSIFNVPGRLAWFLMEIPGVSILLYNMSTLPAKHGIDDLPWQNKVLAGLFAIHYSYRAVMYPLMAPSMAPMNIVVASSAVFFQVMNGTCLGAWLAAYGPTTQEEWRAQLGAGGTLQFVVGISIFYLGLAANYYHDDELREIRRREERRRERVARDEGVRPETVERHYAIPQAGFFKFVLYPHYFLEWCEWFGYWMACGWSCTPAFLFLFNEFVSMLPRAVNGRKWYEERFGPEKIKGRKAVIPGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHF2</accession>
    <name>G4NHF2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_03863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720029.1">
        <property type="nucleotide sequence ID" value="XM_003719981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHF2"/>
    <dbReference type="GeneID" id="2677264"/>
    <dbReference type="KEGG" id="mgr:MGG_03863"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03863"/>
    <dbReference type="HOGENOM" id="CLU_1454708_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHF2"/>
    <dbReference type="OMA" id="ILYDEWR"/>
    <dbReference type="OrthoDB" id="5200458at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="186" mass="19983" checksum="840011973C824353" modified="2011-12-14" version="1">MSAELKLEGRYRLEVVGGNETINRALIQQLPTLRGSIVAGVAADAGSSPSTQACEIFPSSASSATPLTLFADKPSGETIYALRGPSGKGDLQLVQMPAPTGEGRRLVGSSVMSDGWKIVESWGRLLLRYSEEPVGLSHWVAVPREEEGEDGKATKRWTFWWVAPNGANMNDLPGHVIVDIQVVPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIH7</accession>
    <name>G4NIH7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate transporter 4.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_09838</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720404.1">
        <property type="nucleotide sequence ID" value="XM_003720356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIH7"/>
    <dbReference type="SMR" id="G4NIH7"/>
    <dbReference type="FunCoup" id="G4NIH7">
        <property type="interactions" value="282"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NIH7"/>
    <dbReference type="GeneID" id="2680837"/>
    <dbReference type="KEGG" id="mgr:MGG_09838"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09838"/>
    <dbReference type="eggNOG" id="KOG0236">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003182_10_0_1"/>
    <dbReference type="InParanoid" id="G4NIH7"/>
    <dbReference type="OMA" id="TGPMSVT"/>
    <dbReference type="OrthoDB" id="427213at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000036">
        <property type="entry name" value="Putative sulfate transporter YPR003C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
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        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="542"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="600"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="655"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="800" mass="87153" checksum="88B21F5285D9A635" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIJ7</accession>
    <name>G4NIJ7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Minor extracellular protease vpr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_09817</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the peptidase S8 family.</text>
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        <property type="nucleotide sequence ID" value="XM_003720376.1"/>
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    <dbReference type="GeneID" id="2680850"/>
    <dbReference type="KEGG" id="mgr:MGG_09817"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09817"/>
    <dbReference type="eggNOG" id="KOG4266">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003559_2_1_1"/>
    <dbReference type="InParanoid" id="G4NIJ7"/>
    <dbReference type="OMA" id="AYNISYQ"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02124">
        <property type="entry name" value="PA_PoS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 8 9" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466331" evidence="10">
        <location>
            <begin position="21"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="129"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="12">
        <location>
            <begin position="356"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA48057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="902" mass="95183" checksum="1270A9BD8DF524FD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJ14</accession>
    <name>G4NJ14_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MADS box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_02773</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720973.1">
        <property type="nucleotide sequence ID" value="XM_003720925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJ14"/>
    <dbReference type="SMR" id="G4NJ14"/>
    <dbReference type="STRING" id="242507.G4NJ14"/>
    <dbReference type="GeneID" id="2682778"/>
    <dbReference type="KEGG" id="mgr:MGG_02773"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02773"/>
    <dbReference type="eggNOG" id="KOG0015">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063931_1_0_1"/>
    <dbReference type="InParanoid" id="G4NJ14"/>
    <dbReference type="OMA" id="GGHYPQD"/>
    <dbReference type="OrthoDB" id="2284405at2759"/>
    <dbReference type="PHI-base" id="PHI:2188"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00266">
        <property type="entry name" value="MADS_SRF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1810.10:FF:000002">
        <property type="entry name" value="Serum response factor b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050142">
        <property type="entry name" value="MADS-box/MEF2_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033897">
        <property type="entry name" value="SRF-like_MADS-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48019">
        <property type="entry name" value="SERUM RESPONSE FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00350">
        <property type="entry name" value="MADS_BOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="7">
        <location>
            <begin position="55"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA46230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="224" mass="24383" checksum="E949AC98C590690D" modified="2011-12-14" version="1">MAEITDQHDQTSPTELEDAHSVGNGNSAAQENRGIKRARQSAPDDDDDDDEKGGRERRKIEIKFINDKSRRHITFSKRKAGIMKKAYELSVLTGTQVLLLVVSETGLVYTFTTPKLQPLVTKAEGKNLIQACLNAPEPSAGNENGVDDGQVDSPEEPASNIPPPQSRAPGIPSQHNPHGMPQYNMPNVGMDPSAMAYQSYVQRGGPQYGMPPQSGMPQHSSHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJA9</accession>
    <name>G4NJA9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome quality control complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_02697</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NEMF family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721068.1">
        <property type="nucleotide sequence ID" value="XM_003721020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJA9"/>
    <dbReference type="SMR" id="G4NJA9"/>
    <dbReference type="FunCoup" id="G4NJA9">
        <property type="interactions" value="968"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NJA9"/>
    <dbReference type="GeneID" id="2682704"/>
    <dbReference type="KEGG" id="mgr:MGG_02697"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02697"/>
    <dbReference type="eggNOG" id="KOG2030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003612_1_1_1"/>
    <dbReference type="InParanoid" id="G4NJA9"/>
    <dbReference type="OMA" id="MFLEFFA"/>
    <dbReference type="OrthoDB" id="207084at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.310.10:FF:000003">
        <property type="entry name" value="Zinc knuckle domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.310.10">
        <property type="entry name" value="ibrinogen binding protein from staphylococcus aureus domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021846">
        <property type="entry name" value="NFACT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11923">
        <property type="entry name" value="NFACT-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05833">
        <property type="entry name" value="NFACT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="8">
        <location>
            <begin position="559"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="NFACT protein C-terminal" evidence="9">
        <location>
            <begin position="949"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="446"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="699"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="901"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1055"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="344"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="738"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="766"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="828"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="848"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="901"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="918"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="1055"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA46325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1074" mass="117527" checksum="F5AFB31F94745864" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJQ4</accession>
    <name>G4NJQ4_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">MGG_10352</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA45721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003720464.1">
        <property type="nucleotide sequence ID" value="XM_003720416.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NJQ4"/>
    <dbReference type="GeneID" id="2681927"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_10352"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="20"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA45721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="270" mass="29960" checksum="3E8E649AE9B06E62" modified="2011-12-14" version="1">MVKFSLLHSVLPAVARVLAVSLSIPSPRDLFDDPCITFRLPPRSVNATYLNEASVEWPWTQPAFGFGYGKWALAWTSIEEYWDWSNMQNEWYPINSTVSGHQVSDIRPTVIADINSFQLGRNDTVIRTLALDVPLAGETYAWNFTIPALEAHDNTAWTGWGYDFHAQGAPYFVSYDATTTGIKNVSYGVSIYSAREGGPTKETVDEAAACYDRLGSKTFAALFRSMRRTPTDGRRTHELSWHDADTALSVAIGTRPNQSVLGRRGAVLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKK4</accession>
    <name>G4NKK4_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">Putative zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03059</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720622.1">
        <property type="nucleotide sequence ID" value="XM_003720574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKK4"/>
    <dbReference type="SMR" id="G4NKK4"/>
    <dbReference type="STRING" id="242507.G4NKK4"/>
    <dbReference type="GeneID" id="2682612"/>
    <dbReference type="KEGG" id="mgr:MGG_03059"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03059"/>
    <dbReference type="eggNOG" id="KOG4839">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006646_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKK4"/>
    <dbReference type="OMA" id="PHNIRYS"/>
    <dbReference type="OrthoDB" id="1922977at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019607">
        <property type="entry name" value="Putative_zinc-finger_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039278">
        <property type="entry name" value="Red1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21563">
        <property type="entry name" value="ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21563:SF3">
        <property type="entry name" value="ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10650">
        <property type="entry name" value="zf-C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1070"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="785"/>
            <end position="980"/>
        </location>
    </feature>
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        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="87"/>
        </location>
    </feature>
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        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
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            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
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    </feature>
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    </feature>
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    </feature>
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    </feature>
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        </location>
    </feature>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45879.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1168" mass="125003" checksum="E311E8BEC6FA551E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKP7</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721379.1">
        <property type="nucleotide sequence ID" value="XM_003721331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKP7"/>
    <dbReference type="GeneID" id="12985935"/>
    <dbReference type="KEGG" id="mgr:MGG_18056"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18056"/>
    <dbReference type="HOGENOM" id="CLU_1731865_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKP7"/>
    <dbReference type="OMA" id="HKHARNG"/>
    <dbReference type="OrthoDB" id="5210161at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="151" mass="15853" checksum="2B58BBD31BB58317" modified="2011-12-14" version="1">MSSLSLPENLQPADSPFTFHPSLARDPDLAAQFLQSDFAARDRVMAHKHARNGVLAALAANFPPRDPIPDGNAGLEAPEEGSLAATVHDAMQPGAEEAEGEGGPCVVCENRTPKFSGPPPRPAPVRGEGWNIGDCVPADAKSGIRAIGRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLP4</accession>
    <name>G4NLP4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_12568</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720840.1">
        <property type="nucleotide sequence ID" value="XM_003720792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLP4"/>
    <dbReference type="SMR" id="G4NLP4"/>
    <dbReference type="STRING" id="242507.G4NLP4"/>
    <dbReference type="GeneID" id="5050449"/>
    <dbReference type="KEGG" id="mgr:MGG_12568"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12568"/>
    <dbReference type="eggNOG" id="KOG1290">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_81_1_1"/>
    <dbReference type="InParanoid" id="G4NLP4"/>
    <dbReference type="OMA" id="DERHACL"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="100"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA46097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="474" mass="54589" checksum="9FE1532CD956B72C" modified="2011-12-14" version="1">MPQNSAEARAGESLQVNCFVRSYQDFKDCGKKVRDGLRRETKVLCEHLKPSQAALYRVPTFKCTSFQEDGGLFEEENHKNFARGDFYPVELGRILKGTSYQTLIKLGWGDSSTAWMAFDLMSETFVALKICTRLSPEADRQEDCQRRMSIHANPKHPGYPFINHTRPVEPIRRPGGPTRSKPSSEIIPNDERHACLVQKPMWRYWATVYSSPCWRNHHLRRGTKQLLFALDYLHTECGLVHGNVCEANVGYRVPLDETIVRETLGLIKTLPSRTTAARAYVKTVTARDCTDFTLYRSTRFDEKKLGKTTDFCKVLLGSFGQTRVAYEVWDPEGTPKSMYMAPEVLLGLEVTFAADVWNLGLMLWKLWRREYLINGSLDCDGDNPILHWNSTSHMASIVSKIGPPPKDMLERGRFSGRYFTPEGLPRMDCTNQKHERTPKNDSFEDLVWSMVRWRPEDRKTPKQLLEHPWLSEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH03</accession>
    <name>G5EH03_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Isocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGCH7_ch7g337</name>
        <name evidence="10" type="ORF">MGG_02616</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15</strain>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <reference evidence="12" key="4">
        <citation type="submission" date="2024-04" db="PDB data bank">
            <title>High-resolution crystal structure of the MoMcl1 protein.</title>
            <authorList>
                <person name="Liu X.H."/>
                <person name="Zhao W.H."/>
            </authorList>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (1.82 ANGSTROMS) OF 65-607 IN COMPLEX WITH MG(2+)</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Can also use Mn(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721179.1">
        <property type="nucleotide sequence ID" value="XM_003721131.1"/>
    </dbReference>
    <dbReference type="PDB" id="8Z1R">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.82 A"/>
        <property type="chains" value="A/B=65-607"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH03"/>
    <dbReference type="SMR" id="G5EH03"/>
    <dbReference type="FunCoup" id="G5EH03">
        <property type="interactions" value="107"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EH03"/>
    <dbReference type="GeneID" id="2682815"/>
    <dbReference type="KEGG" id="mgr:MGG_02616"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02616"/>
    <dbReference type="eggNOG" id="KOG1260">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019214_2_2_1"/>
    <dbReference type="OMA" id="TVPHADF"/>
    <dbReference type="OrthoDB" id="4078635at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019629">
        <property type="term" value="P:propionate catabolic process, 2-methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.850:FF:000001">
        <property type="entry name" value="Isocitrate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF13">
        <property type="entry name" value="MITOCHONDRIAL 2-METHYLISOCITRATE LYASE ICL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword evidence="12" id="KW-0002">3D-structure</keyword>
    <keyword evidence="4 5 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="165"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 12">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="275"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="492"/>
            <end position="496"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EAQ70930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA46436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="12">
        <source>
            <dbReference type="PDB" id="8Z1R"/>
        </source>
    </evidence>
    <sequence length="607" mass="66744" checksum="1CFACEAC9A6E28A3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHG4</accession>
    <name>G5EHG4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydrophobin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g882</name>
        <name evidence="3" type="ORF">MGG_03079</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720594.1">
        <property type="nucleotide sequence ID" value="XM_003720546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHG4"/>
    <dbReference type="GeneID" id="2682632"/>
    <dbReference type="KEGG" id="mgr:MGG_03079"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03079"/>
    <dbReference type="eggNOG" id="ENOG502RNB9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091421_1_0_1"/>
    <dbReference type="OrthoDB" id="10339976at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834246" description="Hydrophobin" evidence="1">
        <location>
            <begin position="19"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="18915" checksum="6794A078259507D9" modified="2011-12-14" version="1">MLLPQITTILGLASLSQAVNLRFYYSNNCSGNNVVCSNIARNTCCNGNGISVFFGLNRAVEGRVYDRGGCNRLRGVRTSVGSTSFCLRQGNDVMTGAQWRPPPSLRLAAVPEQPEACPAGGDKCESWARPDVLGLADGTEYEIGGLEEAHLALAADGSISSAQDLPEEFKSLVVTTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI01</accession>
    <name>G5EI01_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g133</name>
        <name evidence="3" type="ORF">MGG_18053</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721367.1">
        <property type="nucleotide sequence ID" value="XM_003721319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI01"/>
    <dbReference type="GeneID" id="12985932"/>
    <dbReference type="KEGG" id="mgr:MGG_18053"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18053"/>
    <dbReference type="HOGENOM" id="CLU_2831677_0_0_1"/>
    <dbReference type="OMA" id="WIVIRIL"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="66" mass="7657" checksum="D0ACFFACB7EF27F9" modified="2011-12-14" version="1">MFYDHTIVRSRKSNFSLVQAIKCQLVRFSSGGILVDWYTYGTYLVPSCWIVIRILGSRKEKNDAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4L8</accession>
    <name>A0A151V4L8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_10267</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="JH165178">
        <property type="protein sequence ID" value="KYQ30515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846019.1">
        <property type="nucleotide sequence ID" value="XM_016990514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4L8"/>
    <dbReference type="SMR" id="A0A151V4L8"/>
    <dbReference type="FunCoup" id="A0A151V4L8">
        <property type="interactions" value="445"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A0A151V4L8"/>
    <dbReference type="GeneID" id="2681820"/>
    <dbReference type="KEGG" id="mgr:MGG_10267"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10267"/>
    <dbReference type="eggNOG" id="KOG2682">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4L8"/>
    <dbReference type="OMA" id="TDHEVND"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="PHI-base" id="PHI:11102"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01408">
        <property type="entry name" value="SIRT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="14"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="322"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="449"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="324"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="483"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KYQ30515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="510" mass="54932" checksum="5C0E5B35B30C7751" modified="2016-06-08" version="1">MDDYGLDDVMDRHTSQASPTLDQIARYILANPGSPPGIIILAGAGISTSAGIPDFRSPKTGLYDNLARFSLDSPTDVFDINFFRTNPQPFYSLAPELYPGRYAPTISHAFVALLARKGLLAMLFTQNIDGLEKAAGVPPDLVVEAHGSFDSQRCIDCAQEFPAADMRAHVATSSVPHCGKCGGLVKPDIVFFGEQLPDRFFRAREAHLPDLEGAPIPEILGGARQVVIVMGTSLSVPPFCELPVRAADGVPRLLFNREVVGDFGERAQDVVELGDCDSGVRKLAEMLGWGEELEVEWRRVVGNEEAERQLVRAAAAAAPHPILEMDDGLSEDSSDTSDSASDKDDLMSDDGGNTDHEVNDFSSSSFGAVATPLTLDSVYYNPHQDQMVHISSSLPSVSLAADLACLVPPVEGDFVGSFDHHNFLIDPIDTRQGQSTGYLDHSHAMLDLVPLPHGHGESGSVDDERGNQNLEDGVRNHDIDGPNDTNEGAKTTRTFQLTDSRVQTEGNPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKK9</accession>
    <name>G4MKK9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_04419</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711004.1">
        <property type="nucleotide sequence ID" value="XM_003710956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKK9"/>
    <dbReference type="SMR" id="G4MKK9"/>
    <dbReference type="STRING" id="242507.G4MKK9"/>
    <dbReference type="ESTHER" id="mago7-g4mkk9">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="2677739"/>
    <dbReference type="KEGG" id="mgr:MGG_04419"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04419"/>
    <dbReference type="eggNOG" id="KOG1516">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_5_1"/>
    <dbReference type="InParanoid" id="G4MKK9"/>
    <dbReference type="OMA" id="DQDFDMC"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005132151" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="24"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="33"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA58392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="539" mass="58636" checksum="989ECEA35601A598" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKR9</accession>
    <name>G4MKR9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like modifier HUB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06666</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709371.1">
        <property type="nucleotide sequence ID" value="XM_003709323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKR9"/>
    <dbReference type="SMR" id="G4MKR9"/>
    <dbReference type="STRING" id="242507.G4MKR9"/>
    <dbReference type="GeneID" id="2684839"/>
    <dbReference type="KEGG" id="mgr:MGG_06666"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06666"/>
    <dbReference type="eggNOG" id="KOG3493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077999_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKR9"/>
    <dbReference type="OMA" id="QSSEPMI"/>
    <dbReference type="OrthoDB" id="3881at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039732">
        <property type="entry name" value="Hub1/Ubl5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13042">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="239" mass="27487" checksum="BBCF992DAB7D62E6" modified="2011-12-14" version="1">MAGGSRSRSPRRDGRSEDADARRDHDRAGDRDRRGADRDGDRDRNRDRDRRDRDRNRDRDSDRDRGRDRPRQPRGTGGFRWKDKRSDNNLGEEDNRRGGALERGYRNRSPRRDRDRDRDRQGRDGREDRRDNSRRDQDRSSRPSASSSAAPTAPAPSGAGEEMIVVHINDRLGTKAAIPCFASDKVREFKIMVAARIGREPHEILLKRQGERPFKDQLSLEDYGVSNGVQLDLEVDTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML73</accession>
    <name>G4ML73_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lustrin A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709421.1">
        <property type="nucleotide sequence ID" value="XM_003709373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML73"/>
    <dbReference type="GeneID" id="5049662"/>
    <dbReference type="KEGG" id="mgr:MGG_11870"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11870"/>
    <dbReference type="eggNOG" id="ENOG502S16F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_446928_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML73"/>
    <dbReference type="OMA" id="HISFEKR"/>
    <dbReference type="OrthoDB" id="3923593at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="611" mass="58657" checksum="5AABF8E919593A2B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLM0</accession>
    <name>G4MLM0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709465.1">
        <property type="nucleotide sequence ID" value="XM_003709417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLM0"/>
    <dbReference type="SMR" id="G4MLM0"/>
    <dbReference type="STRING" id="242507.G4MLM0"/>
    <dbReference type="GeneID" id="2684924"/>
    <dbReference type="KEGG" id="mgr:MGG_06751"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06751"/>
    <dbReference type="eggNOG" id="ENOG502S8KA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1235239_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLM0"/>
    <dbReference type="OrthoDB" id="3928876at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16015">
        <property type="entry name" value="Promethin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="224" mass="24670" checksum="03C3A74815F972CA" modified="2011-12-14" version="1">MATQEQQMSIQEQKNALKESMKNHKNALKGSLKEQQAALEKSLKESTEAAKEQASGFIAFLQRQLDRVVSPETRDQAYERMQEFAKERPFLFTFLVAQALTCAVPVALFAAFTSSVFVLSLGAAVLFSLFWLGVAVMVLVPTLFVTVTIGAVLFCWAVVIRFAYNTLPAAMKNFFAGSREVAEEKYTDYSDALNRAKKAIKDSANRNGTNGTYTNGATNGTHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMN9</accession>
    <name>G4MMN9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710423.1">
        <property type="nucleotide sequence ID" value="XM_003710375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMN9"/>
    <dbReference type="GeneID" id="2675895"/>
    <dbReference type="KEGG" id="mgr:MGG_05552"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05552"/>
    <dbReference type="eggNOG" id="ENOG502S6PP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069867_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMN9"/>
    <dbReference type="OMA" id="VYVVRWM"/>
    <dbReference type="OrthoDB" id="509124at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07822">
        <property type="entry name" value="SRPBCC_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="211" mass="22674" checksum="2635941EC7164B8C" modified="2011-12-14" version="1">MANPTATIPQPAISPDDAEPTRWLDQPLPTPKFGDHGYCTIASSVRIAAPPQTCLGVVLHAPGYAPPQGCWNNWVRKIAITAPGADDAAGIPAELTGPDYLSHGARFDMSVVMDQTATSSPRVQSMDVTACEALADGRTGFRVGWTYCMFGLHCERIQEFVDDGQGGTLYATWETFGGVIARIVWMTNAAGIQRGFVEWGRGLKEKAEAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNU5</accession>
    <name>G4MNU5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Minichromosome loss protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_06969</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709714.1">
        <property type="nucleotide sequence ID" value="XM_003709666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNU5"/>
    <dbReference type="SMR" id="G4MNU5"/>
    <dbReference type="FunCoup" id="G4MNU5">
        <property type="interactions" value="347"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MNU5"/>
    <dbReference type="GeneID" id="2685142"/>
    <dbReference type="KEGG" id="mgr:MGG_06969"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06969"/>
    <dbReference type="eggNOG" id="KOG1274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004219_2_1_1"/>
    <dbReference type="InParanoid" id="G4MNU5"/>
    <dbReference type="OMA" id="RYAHTNG"/>
    <dbReference type="OrthoDB" id="427368at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000792">
        <property type="term" value="C:heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903461">
        <property type="term" value="P:Okazaki fragment processing involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057646">
        <property type="entry name" value="WD40_WDHD1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048591">
        <property type="entry name" value="WDHD1/CFT4_hel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20946">
        <property type="entry name" value="Ctf4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24817">
        <property type="entry name" value="WD40_WDHD1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDHD1 first WD40" evidence="9">
        <location>
            <begin position="9"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="227"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="7">
        <location>
            <begin position="409"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 helical bundle" evidence="8">
        <location>
            <begin position="744"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="336"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="700"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="717"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA57102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="854" mass="95034" checksum="1E7063CCF7D0532D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP61</accession>
    <name>G4MP61_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_02160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708932.1">
        <property type="nucleotide sequence ID" value="XM_003708884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP61"/>
    <dbReference type="GeneID" id="2681071"/>
    <dbReference type="KEGG" id="mgr:MGG_02160"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02160"/>
    <dbReference type="eggNOG" id="ENOG502SNA9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_545215_0_0_1"/>
    <dbReference type="InParanoid" id="G4MP61"/>
    <dbReference type="OMA" id="NAYWERF"/>
    <dbReference type="OrthoDB" id="5421689at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="43"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="318"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="475"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="419"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="434"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="500" mass="54356" checksum="9DE247BC2F988FB6" modified="2011-12-14" version="1">MSANLTFSLPPPPSGIDLGETRVPDIYGALISTWALAALMLGLRATVRRSMGGTAWWDDILAWMALVRIPPKRGLCSELVLDVLVAATAQVLVVIVYMIPNGTGRHIWAGTIHSSRAWAIGMFVIQLTYVLVLGLAKYSTLCLYWRLFGAEKRNRIPIWIMGGLVTAWVVAILATTVFLCLPVNAYWERFNPENPMPFNQFECGIDSKRFYIGTAIPTVVTNLLLLAMPVPYVWRLRMPTPQKVAVLAVFLFGAILTVVSAVRLVVIVDVDVADPDMTWNIVDSIIWSHVEGNIAILCCCLPTLKPILDICTAGTTKAAERVNRESRKPAGAGLGGGRHNGSSTLVRTPQSQSGNEIPQWLDESRSRSEPQQGSEPGSSSGEVANLRTMTEIKAHRRPPPAHANPCVGGISSSCGSLGRMRSLTSSPTLSRSRSLSRARLAKSRHSSDDGARSDVSSIEEVPGITVTFDVVVSSERVEMPEKPVQLEQLRFSSSSSSSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPN2</accession>
    <name>G4MPN2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_14367</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708993.1">
        <property type="nucleotide sequence ID" value="XM_003708945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPN2"/>
    <dbReference type="GeneID" id="5051592"/>
    <dbReference type="KEGG" id="mgr:MGG_14367"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14367"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="InParanoid" id="G4MPN2"/>
    <dbReference type="OMA" id="NMILHKF"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000364">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF79">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="64"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="526" mass="57488" checksum="499D39D32226CFF9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQU0</accession>
    <name>G4MQU0_PYRO7</name>
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        <submittedName>
            <fullName evidence="6">Bilirubin oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_13764</name>
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    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710783.1">
        <property type="nucleotide sequence ID" value="XM_003710735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQU0"/>
    <dbReference type="SMR" id="G4MQU0"/>
    <dbReference type="STRING" id="242507.G4MQU0"/>
    <dbReference type="GeneID" id="5048986"/>
    <dbReference type="KEGG" id="mgr:MGG_13764"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13764"/>
    <dbReference type="eggNOG" id="ENOG502QR4X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009100_2_2_1"/>
    <dbReference type="InParanoid" id="G4MQU0"/>
    <dbReference type="OMA" id="PYSGRYV"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13866">
        <property type="entry name" value="CuRO_2_BOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13889">
        <property type="entry name" value="CuRO_3_BOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48267:SF1">
        <property type="entry name" value="BILIRUBIN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48267">
        <property type="entry name" value="CUPREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465386" evidence="3">
        <location>
            <begin position="24"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="109"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="411"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA58171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="629" mass="70176" checksum="DA31DBFA63764DC7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRB9</accession>
    <name>G4MRB9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710856.1">
        <property type="nucleotide sequence ID" value="XM_003710808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRB9"/>
    <dbReference type="GeneID" id="12986469"/>
    <dbReference type="KEGG" id="mgr:MGG_16507"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16507"/>
    <dbReference type="HOGENOM" id="CLU_2498285_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRB9"/>
    <dbReference type="OrthoDB" id="10660615at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="86" mass="9779" checksum="A3DB22AE91DB25C5" modified="2011-12-14" version="1">MHRAVGERVENGRESSKQKLEQKHGNQRSPWIYGRRSKSVATPIATPEFLTEMQSTTGASVPCHWTIIYHALMMGYTSHSKHGTWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRI2</accession>
    <name>G4MRI2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_02434</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709221.1">
        <property type="nucleotide sequence ID" value="XM_003709173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRI2"/>
    <dbReference type="SMR" id="G4MRI2"/>
    <dbReference type="FunCoup" id="G4MRI2">
        <property type="interactions" value="436"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRI2"/>
    <dbReference type="GeneID" id="2681531"/>
    <dbReference type="KEGG" id="mgr:MGG_02434"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02434"/>
    <dbReference type="eggNOG" id="KOG0936">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061221_2_0_1"/>
    <dbReference type="InParanoid" id="G4MRI2"/>
    <dbReference type="OMA" id="DLIFNWQ"/>
    <dbReference type="OrthoDB" id="10261046at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000001">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA56609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="187" mass="20323" checksum="BE58C6DBB49D2B06" modified="2011-12-14" version="1">MINAFLVFNGQGQPRLTKFYTQLETNMQQRLISEIFTLVSNRPTGSCNFLPLPPLLAASGTSHTDSTEQNDVPSLVTYRNYATLYFIVISTATESPLALIDLIQVYVEALDKLFENVCELDLIFNFETLHSTLSEMIVGGVVVETNLDRIVAGVRAQGTVAKRQTNDGRGGGGGIGSGLGIGVWHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRV1</accession>
    <name>G4MRV1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZW10 C-terminal helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709232.1">
        <property type="nucleotide sequence ID" value="XM_003709184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRV1"/>
    <dbReference type="SMR" id="G4MRV1"/>
    <dbReference type="STRING" id="242507.G4MRV1"/>
    <dbReference type="GeneID" id="2681540"/>
    <dbReference type="KEGG" id="mgr:MGG_02443"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02443"/>
    <dbReference type="eggNOG" id="KOG2163">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006571_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRV1"/>
    <dbReference type="OMA" id="REVQYSQ"/>
    <dbReference type="OrthoDB" id="534815at2759"/>
    <dbReference type="PHI-base" id="PHI:873"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="720"/>
            <end position="870"/>
        </location>
    </feature>
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        </location>
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            <end position="438"/>
        </location>
    </feature>
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            <end position="454"/>
        </location>
    </feature>
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            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="881" mass="96620" checksum="37C64A9A8209BE10" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">MGG_16521</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710963.1">
        <property type="nucleotide sequence ID" value="XM_003710915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS93"/>
    <dbReference type="GeneID" id="12986871"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_16521"/>
    <dbReference type="HOGENOM" id="CLU_2278012_0_0_1"/>
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            <end position="21"/>
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    </feature>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="102" mass="11276" checksum="69A97109C69EE10F" modified="2011-12-14" version="1">MESRELLIPQSRGSFPRTNGVQAQIPKPHMQQTCVYSCLAAQPQVFGASCRRGELTLRGTPLMIKVYEASRKLAIDGSRDIDCWLDRAKANGFTHGIPTSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSQ0</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">MGG_07088</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715278.1">
        <property type="nucleotide sequence ID" value="XM_003715230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSQ0"/>
    <dbReference type="GeneID" id="2682973"/>
    <dbReference type="KEGG" id="mgr:MGG_07088"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07088"/>
    <dbReference type="eggNOG" id="ENOG502SE07">
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="104" mass="11265" checksum="397DB22466B422CB" modified="2011-12-14" version="1">MTMTDPSTAGSNAMAEGGQGSAPIQQAPGLQDIAPKDTGAALNDPFPDRRQSDEWDASKVPPSRFQKRKGSIYSTPGSRDGHVDRNTQHKFHETHAEKGYGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSR2</accession>
    <name>G4MSR2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MOSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07097</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003715290.1">
        <property type="nucleotide sequence ID" value="XM_003715242.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MSR2"/>
    <dbReference type="SMR" id="G4MSR2"/>
    <dbReference type="STRING" id="242507.G4MSR2"/>
    <dbReference type="GeneID" id="2682982"/>
    <dbReference type="KEGG" id="mgr:MGG_07097"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07097"/>
    <dbReference type="eggNOG" id="KOG2362">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="InParanoid" id="G4MSR2"/>
    <dbReference type="OMA" id="VYTACRT"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF23">
        <property type="entry name" value="MOSC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G05900)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="MOSC" evidence="2">
        <location>
            <begin position="274"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="454" mass="51321" checksum="CCBAB67CB5B1C9AD" modified="2011-12-14" version="1">MEDILLALSNGTWHKDPGTISILLLTVLAFLVPMIYVYPPFPPRESDALAETHSKVGLEPSAAKPGLRAAQALPSDVLSAGPPRVQSLWIYPVKSCAGIELDRSVVLPSGLEFDRLFTLAQLKSPFPVRLDSDADEKSRHGWEFITQRQFPALANVRVELWRPDRAKCERRGEKIRESYLILRFPWMEEGFRGTLAWVAAKTLRGVDARPEKEIMLPVEFPSEADIRNKDYKYENVKIWKETVTALNMSSELSDELQRYLGVSNKLALFRIDPDKLREVYRGAPTSEVAGYQPVTGFQDAFPLHLLNLSSVRDLNEKVSQDENLKTLDARRFRANIILTGLPPYEEEKWKSIQLVSDGKSSEETAEFDVSCRTVRCKMPNVNPDNGIKHEKEPDHALRKYRNVDEGAPLNGCLGMQLTPMFKMTGSRVLELESTVKIGMEVKVKGLGSHKYIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT11</accession>
    <name>G4MT11_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">6-phosphogluconate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01506</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714477.1">
        <property type="nucleotide sequence ID" value="XM_003714429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT11"/>
    <dbReference type="SMR" id="G4MT11"/>
    <dbReference type="STRING" id="242507.G4MT11"/>
    <dbReference type="GeneID" id="2679270"/>
    <dbReference type="KEGG" id="mgr:MGG_01506"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01506"/>
    <dbReference type="eggNOG" id="KOG0409">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035117_5_1_1"/>
    <dbReference type="InParanoid" id="G4MT11"/>
    <dbReference type="OMA" id="IFSCIAN"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF3">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G11600)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="5">
        <location>
            <begin position="7"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="6">
        <location>
            <begin position="179"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="309" mass="32762" checksum="65131E5F030DDC94" modified="2011-12-14" version="1">MAPQLLWIGLGNMGRGMCRNIVEKAALDGLPLLLHNRSAQRAVDLKGSLPDGKAEVVTDLAQGVAKADVIFTCVANDAAVRETLDAAIASGNIKGKLFIDCSTIHPDTTESVSKKIVDQGAEFVAAPIFGPPAAADAGTLVAVLAGPRSSVERARPYFKGVTSRAEIEMVDRTPQTALTLKVIGNTFIVNMIEQLAEGHVLAEKSGLGTEYLHQFVEHVFPGAYTAYSQRMLTGDYHKREEPLFAVDLARKDAGHALALAKKAGTKLPNVEAADAHLAQVKEHSGAKGDIAGIYGAVRKEAGLKFENDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT98</accession>
    <name>G4MT98_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713651.1">
        <property type="nucleotide sequence ID" value="XM_003713603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT98"/>
    <dbReference type="GeneID" id="12987142"/>
    <dbReference type="KEGG" id="mgr:MGG_15551"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15551"/>
    <dbReference type="HOGENOM" id="CLU_2622480_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT98"/>
    <dbReference type="OrthoDB" id="10416996at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="78" mass="8224" checksum="69D50F557177A92A" modified="2011-12-14" version="1">MSCQCQQTTKPPGATASSEDATRAGNTSAPTKSTDGLGPDASADAREDSSPPPQQPPPQQPPYYYPGWYESESAPRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTI4</accession>
    <name>G4MTI4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">homoisocitrate dehydrogenase</fullName>
            <ecNumber evidence="12">1.1.1.87</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_01566</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(2R,3S)-homoisocitrate + NAD(+) = 2-oxoadipate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:11900"/>
            <dbReference type="ChEBI" id="CHEBI:15404"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57499"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.87"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.87" evidence="12"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714542.1">
        <property type="nucleotide sequence ID" value="XM_003714494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTI4"/>
    <dbReference type="SMR" id="G4MTI4"/>
    <dbReference type="FunCoup" id="G4MTI4">
        <property type="interactions" value="576"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTI4"/>
    <dbReference type="GeneID" id="2679512"/>
    <dbReference type="KEGG" id="mgr:MGG_01566"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01566"/>
    <dbReference type="eggNOG" id="KOG0785">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_1_1"/>
    <dbReference type="InParanoid" id="G4MTI4"/>
    <dbReference type="OMA" id="DSFVMGE"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047046">
        <property type="term" value="F:homoisocitrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000012">
        <property type="entry name" value="Homoisocitrate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF48">
        <property type="entry name" value="HOMOISOCITRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="13">
        <location>
            <begin position="8"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00052540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA54735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="360" mass="38170" checksum="BB649AAF21FEFD7C" modified="2011-12-14" version="1">MATARALRIGLIAGDGIGKDVVPAGRRVLEALPASLGLRFSFVDLQAGFQTFEETGSALPDRTVETLKGECDGALFGAVSSPTKPVKGYSSPIVGLRKKLDLYANVRPVKTVVSAPRPIDMVIVRENTEDLYVKDERTFDAPDGSGPVAEAIKRISYRASHRIASMAGEIALRRQKIRAAGAPSIHSSPLVTITHKSNVLSQTDGLFRSTAKEALADPKYAGSVAVEEQIVDSMVYKLFRQPEDYDVIVAPNLYGDILSDGAAALVGSLGLVPSANVGDGFVMGEPCHGSAPDIMGKNIANPIATLRSAALMLEFLNEEEAAAKIYAAVDANLVEGKVLSPDLGGKATTDQVLEDILRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTN2</accession>
    <name>G4MTN2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein ypt4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715397.1">
        <property type="nucleotide sequence ID" value="XM_003715349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTN2"/>
    <dbReference type="SMR" id="G4MTN2"/>
    <dbReference type="STRING" id="242507.G4MTN2"/>
    <dbReference type="GeneID" id="2683174"/>
    <dbReference type="KEGG" id="mgr:MGG_07191"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07191"/>
    <dbReference type="eggNOG" id="KOG0098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_23_1_1"/>
    <dbReference type="InParanoid" id="G4MTN2"/>
    <dbReference type="OMA" id="ANGVMQY"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="290" mass="31122" checksum="4F0D5421474F9F55" modified="2011-12-14" version="1">MADLDSAAGPTWDYIAKLVCIGDSGCGKSSLTVRLCEGRFVTHHDVTIGVEFGSRVVPVGPPYSRRLAAASTSSSSSLHSRPATADANATPSATGGLPAPPRPPAPDPPQKHMKLSLWDTAGQETYKSVTRSYFRGASGALLVFDLSRRQTFQHVTDWLNDLRQIAEEDIVVVLVGNKADLTRTSSSGGAEGESAADDVPNKREVTREEAEAWAKRNNVLEYVETSAKSGENVEMAFMRVAERIFQNIEAGKYDLNDRRSGVKGPAATVPGARTLQLQPDPRKGSSFGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU59</accession>
    <name>G4MU59_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione-specific gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_04817</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.2.7" evidence="1"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713747.1">
        <property type="nucleotide sequence ID" value="XM_003713699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU59"/>
    <dbReference type="SMR" id="G4MU59"/>
    <dbReference type="FunCoup" id="G4MU59">
        <property type="interactions" value="338"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MU59"/>
    <dbReference type="GeneID" id="2677749"/>
    <dbReference type="KEGG" id="mgr:MGG_04817"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04817"/>
    <dbReference type="eggNOG" id="KOG3182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070703_0_0_1"/>
    <dbReference type="InParanoid" id="G4MU59"/>
    <dbReference type="OMA" id="DHREKDG"/>
    <dbReference type="OrthoDB" id="1933483at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061928">
        <property type="term" value="F:glutathione specific gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.10:FF:000021">
        <property type="entry name" value="Gamma-glutamylcyclotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006840">
        <property type="entry name" value="ChaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192">
        <property type="entry name" value="CATION TRANSPORT PROTEIN CHAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192:SF2">
        <property type="entry name" value="GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04752">
        <property type="entry name" value="ChaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="200"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="232" mass="26391" checksum="8EFC4715BB5FAA78" modified="2011-12-14" version="1">MDACGKPLPDDDGEFWIFGYGSLIWKPPPHFDCRIPGWVTGYVRRFWQASEDHRGTPEKPGRVVTLLERSFWETLTDHHEDAPDRVWGVAYRIKADKVDEVKDYLDIREINGYTIHYTPFHPADRSAPIRTLVYIGTPDNPQFVGPQDPQALAEHIHRSEGPSGLNRDYLLSLDDALNQLGPESGDEHVADLSRRVRAMQTDSAAQVDTASQQSDFRKVHRAEEKEEAEKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW41</accession>
    <name>G4MW41_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_11289</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714001.1">
        <property type="nucleotide sequence ID" value="XM_003713953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW41"/>
    <dbReference type="SMR" id="G4MW41"/>
    <dbReference type="STRING" id="242507.G4MW41"/>
    <dbReference type="CAZy" id="GH2">
        <property type="family name" value="Glycoside Hydrolase Family 2"/>
    </dbReference>
    <dbReference type="GeneID" id="2679949"/>
    <dbReference type="KEGG" id="mgr:MGG_11289"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11289"/>
    <dbReference type="eggNOG" id="KOG2024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002346_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW41"/>
    <dbReference type="OMA" id="HYTNIDY"/>
    <dbReference type="OrthoDB" id="408320at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005990">
        <property type="term" value="P:lactose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF2">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="LacZ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta galactosidase small chain/" evidence="7">
        <location>
            <begin position="745"/>
            <end position="1043"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1047" mass="116566" checksum="90CB0D829CB65B88" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX49</accession>
    <name>G4MX49_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UbiA prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_08003</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714954.1">
        <property type="nucleotide sequence ID" value="XM_003714906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX49"/>
    <dbReference type="STRING" id="242507.G4MX49"/>
    <dbReference type="GeneID" id="2678236"/>
    <dbReference type="KEGG" id="mgr:MGG_08003"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08003"/>
    <dbReference type="eggNOG" id="ENOG502SNAR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063928_0_0_1"/>
    <dbReference type="InParanoid" id="G4MX49"/>
    <dbReference type="OMA" id="TIWLFIA"/>
    <dbReference type="OrthoDB" id="434972at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13965">
        <property type="entry name" value="PT_UbiA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050475">
        <property type="entry name" value="Prenyltransferase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42723:SF1">
        <property type="entry name" value="CHLOROPHYLL SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="373" mass="40617" checksum="CF693053166C9E2D" modified="2011-12-14" version="1">MPSHSQVTSIHTKNMPHHKDMANILSPMADSSVMHFKKFKEQVHSQRKNTGRELTRFLETIWLFTESDIKTILAPSVLFALTNGIALSLLLPESAGIPSPSEILARIPVITVYVWISLMVLCIQNQKSPDAVEEDRINKPTRPLPSGKVSSDEAGTLLVAFIIIAVLGSYCLGAPVESILVIVLGYIYNDLEGAEHPFFKNVLNSLGIPCFPIGALQVAINPAPHTAAALAGSGPSVPLLLWRWILVLVAAIFFTIHIQDIKDQEGDACRNRKTVPLVYGDSAGRWLVVVPLLAWSVALPILWGFTSPTAASLLGHAPLLLLALVVSARTFLYKSVAADKKTFKIYCLWLIAMYCLPLSRALLGGEGLMLVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX56</accession>
    <name>G4MX56_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">D-amino-acid oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_08011</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DAMOX/DASOX family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714961.1">
        <property type="nucleotide sequence ID" value="XM_003714913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX56"/>
    <dbReference type="SMR" id="G4MX56"/>
    <dbReference type="STRING" id="242507.G4MX56"/>
    <dbReference type="GeneID" id="2678277"/>
    <dbReference type="KEGG" id="mgr:MGG_08011"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08011"/>
    <dbReference type="eggNOG" id="KOG3923">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034311_1_0_1"/>
    <dbReference type="InParanoid" id="G4MX56"/>
    <dbReference type="OMA" id="DLWELQP"/>
    <dbReference type="OrthoDB" id="409956at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003884">
        <property type="term" value="F:D-amino-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006181">
        <property type="entry name" value="D-amino_acid_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023209">
        <property type="entry name" value="DAO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530">
        <property type="entry name" value="D-AMINO ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11530:SF16">
        <property type="entry name" value="D-AMINO ACID OXIDASE (AFU_ORTHOLOGUE AFUA_5G11290)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000189">
        <property type="entry name" value="D-aa_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00677">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465439" evidence="7">
        <location>
            <begin position="17"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="8">
        <location>
            <begin position="3"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>D-dopa</name>
            <dbReference type="ChEBI" id="CHEBI:149689"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000189-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="363" mass="39642" checksum="7AC40AF87269364F" modified="2011-12-14" version="1">MPKIVVLGAGVSGLTAALLLSRNKDNDITVIAKHMPGDYDIEYASPWAGANVLPMNTVEDSRWERRTFPELKRLAEEVPEAGIHLLKVRLFRRTPASEDNETQTALDPIFAKDPWYSEMFDDFRTLSKDELPDGVVSANEFGSVCINTMLYLPWLVGQCRANGVVFNRANLTHIAEAAARHHSGAKADLVVNATGVTACKLGGVMDAAVQPARGQVVVVRNELPLMLGATLAAEDDAEHPDEMVYCMTRAAGGGTVIGGCYQKGNWDPNPDPNLAVRIMSRMVEFWPEIADGKGVAGLDVIRHGVGLRPYREGGVRIEKERLSDGTWVVHNYGHAGWGYQGSYGCAERVVELVDESFKGKPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX91</accession>
    <name>G4MX91_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715795.1">
        <property type="nucleotide sequence ID" value="XM_003715747.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715796.1">
        <property type="nucleotide sequence ID" value="XM_003715748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX91"/>
    <dbReference type="GeneID" id="2678646"/>
    <dbReference type="KEGG" id="mgr:MGG_08287"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08287"/>
    <dbReference type="HOGENOM" id="CLU_1740905_0_0_1"/>
    <dbReference type="OrthoDB" id="5237224at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="150" mass="16535" checksum="FF7FECF8742CDEA9" modified="2011-12-14" version="1">MSQSTTISICKPALQTESAELDSQVDLSSQPSSWGLVNTVLRVDVLLINALVVLKLAMHWCSTSEQPSEPLPSPPPSCFPREDGTSECYESRGRCGLIVPAVLIALLLACMPVVKAIVDTRRQLPLSSLRPAIRQRRRLSTKRKTVRWAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXE9</accession>
    <name>G4MXE9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_10745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713286.1">
        <property type="nucleotide sequence ID" value="XM_003713238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXE9"/>
    <dbReference type="SMR" id="G4MXE9"/>
    <dbReference type="GeneID" id="2676267"/>
    <dbReference type="KEGG" id="mgr:MGG_10745"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10745"/>
    <dbReference type="eggNOG" id="KOG1399">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032067_2_0_1"/>
    <dbReference type="InParanoid" id="G4MXE9"/>
    <dbReference type="OMA" id="GPWYGRV"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051820">
        <property type="entry name" value="FAD-binding_MO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43872">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G02570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43872:SF1">
        <property type="entry name" value="MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G02570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA53479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="546" mass="61445" checksum="D09C89597D2AA9C9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXH8</accession>
    <name>G4MXH8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7708 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713315.1">
        <property type="nucleotide sequence ID" value="XM_003713267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXH8"/>
    <dbReference type="SMR" id="G4MXH8"/>
    <dbReference type="GeneID" id="2676390"/>
    <dbReference type="KEGG" id="mgr:MGG_14097"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14097"/>
    <dbReference type="eggNOG" id="ENOG502RB3S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027363_1_0_1"/>
    <dbReference type="InParanoid" id="G4MXH8"/>
    <dbReference type="OMA" id="QNSGIAC"/>
    <dbReference type="OrthoDB" id="4840035at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056125">
        <property type="entry name" value="DUF7708"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619:SF3">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24809">
        <property type="entry name" value="DUF7708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7708" evidence="1">
        <location>
            <begin position="144"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="654" mass="72421" checksum="D68C75B6F4A367CE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXQ2</accession>
    <name>G4MXQ2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_08044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714996.1">
        <property type="nucleotide sequence ID" value="XM_003714948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXQ2"/>
    <dbReference type="GeneID" id="2678334"/>
    <dbReference type="KEGG" id="mgr:MGG_08044"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08044"/>
    <dbReference type="eggNOG" id="ENOG502RS6N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042420_3_1_1"/>
    <dbReference type="InParanoid" id="G4MXQ2"/>
    <dbReference type="OMA" id="QELMILW"/>
    <dbReference type="OrthoDB" id="5275938at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="41035" checksum="6DCBB6FFCB4431AF" modified="2011-12-14" version="1">MPTPVKPKPVKVSPTPIKRKAEELQDTTIYFDQKGDLRFMVGAEERVFVVCSRTVSRASVVFERMLYGPFAEKKPDDTDSDWVVKLPEDSSKGLEVIFNVVHARFKLVTDFLGLDDLFDVMVMADKYDTMEPIQPWCRRWAENAKRIYSCGTERGQELMILWTAWKLGSSALYEQAAVRLLPRISRPPSTSRSPTTVDIKSYLVGEQRMSEMDGFKYAGSASIIQPVLRVREIVLQRMIDAVNLGKRELMNEKKTSPCQVRYQENGPKNKRQACKTMLAGSICLNQAAWSKVPTFAKDVCHSVESFQHEIDSVLDTLMTLTGHNRCSPKEMIVDDVKKASVLETTSIFIDRKLYRCLVSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXX1</accession>
    <name>G4MXX1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715868.1">
        <property type="nucleotide sequence ID" value="XM_003715820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXX1"/>
    <dbReference type="GeneID" id="2678659"/>
    <dbReference type="KEGG" id="mgr:MGG_08218"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08218"/>
    <dbReference type="HOGENOM" id="CLU_1686981_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXX1"/>
    <dbReference type="OrthoDB" id="10581064at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="156" mass="17525" checksum="1C917072C8E1E587" modified="2011-12-14" version="1">MAPAISSTPRNRIDETLELETHQTSFATYFTQPLKPVQAKQSVPGTSGYTSAAASSKPYAPAAPKNTVMPPTSTVKPNIQKQQRQPGEAQSGNFCWHCHWHHFSRSLCGIGRLLDFFPVQKVRKELQEHQEWHMDGKPNSFIQRRIPAEGDAVQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY18</accession>
    <name>G4MY18_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713353.1">
        <property type="nucleotide sequence ID" value="XM_003713305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY18"/>
    <dbReference type="SMR" id="G4MY18"/>
    <dbReference type="GeneID" id="12986225"/>
    <dbReference type="KEGG" id="mgr:MGG_15515"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15515"/>
    <dbReference type="HOGENOM" id="CLU_548686_0_0_1"/>
    <dbReference type="InParanoid" id="G4MY18"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="497" mass="57875" checksum="756EDB42AC9B3CE5" modified="2011-12-14" version="1">MPDKIEDIYRQMWSKLAKDKGDPRPARTALYFKRCMVEKDRSQQYFLNLLLVALRSTDHKLHLPAFEDNLIDRLGSLLRTCEFIEENIDNDSLGFIDRVYMGEEAAVLFRMHREGYMETIDFEPVNLVWGNETHKGCEELIRYANDDMVFRFVHRSVYDFLTDTKEGTRLLDRCQLSIEDIHEKLTEVSNLRFSTRPDDAREKLVDALATRFEYWTDRIVLLHGRIHPADRVQFHEDTFSMVTPLSITLAEGINAFYEDTYKQRHTGMVQTSRPAWTYFLARCQFFLDGECSIHDEILLWIGHPDSEAFQTTYKAKARFLRSYVDHRFGLYGMENQDTIAICVLSFPIPLVLRYILQALKCWEPTSWAKDLPAFASLEKVAMSQDGIASQHKTAESPVQPLILVNKRIHDLHEAERYYEGYMERSFTKVTDQTDQVILRDLIVGFLKDPKSVLDKRKHQQPINQLAEADGRCDETPVKLEQHLVKAGYLRVGLAGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY48</accession>
    <name>G4MY48_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714186.1">
        <property type="nucleotide sequence ID" value="XM_003714138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY48"/>
    <dbReference type="GeneID" id="2679439"/>
    <dbReference type="KEGG" id="mgr:MGG_01273"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01273"/>
    <dbReference type="eggNOG" id="ENOG502RJ54">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067615_0_0_1"/>
    <dbReference type="InParanoid" id="G4MY48"/>
    <dbReference type="OMA" id="QRCLLIC"/>
    <dbReference type="OrthoDB" id="3537340at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="352" mass="38439" checksum="17896B2E22474EFE" modified="2011-12-14" version="1">MSTDIGLTDNMVSITSGKGANDINPALCEHYAGPFSRLDRVHFDLLYWVLFGGNILLLSFVSFWYSRTSERTKDLRSDDSKFRYLHLRCLYVSASCASVSVVMVVIEVYALLALQFCDGEDLMSLYWATWTMLQFGSVIAIFGIILHMALVLQGHDRPPWALALGTPVLVVAGLGNLVNSMLHRKGTKVMERTRSRSRANSKAGSLSMSQTPTIRDESVEALPRRASPQPQAATPLLQQAAFVGTAPDGGIIIQFSQSSPDLECRGRLLSRDNEGRVMVSFSRDKVMFADEQPQPQQQPPKAALVQQQIASEPSSSSSSPRRSNTRAAPNLPLMSDLNLGAPAAPPSSVAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ06</accession>
    <name>G4MZ06_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein phosphatase 2C homolog 2</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_01351</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714280.1">
        <property type="nucleotide sequence ID" value="XM_003714232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ06"/>
    <dbReference type="SMR" id="G4MZ06"/>
    <dbReference type="FunCoup" id="G4MZ06">
        <property type="interactions" value="1411"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZ06"/>
    <dbReference type="GeneID" id="2679724"/>
    <dbReference type="KEGG" id="mgr:MGG_01351"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01351"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013173_4_3_1"/>
    <dbReference type="InParanoid" id="G4MZ06"/>
    <dbReference type="OMA" id="GPGIRNQ"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="PHI-base" id="PHI:123078"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990439">
        <property type="term" value="F:MAP kinase serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071470">
        <property type="term" value="P:cellular response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903753">
        <property type="term" value="P:negative regulation of p38MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000016">
        <property type="entry name" value="Protein phosphatase 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF565">
        <property type="entry name" value="AT28366P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="385"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="409"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00074087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA54473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="451" mass="48774" checksum="1D4FCB7F0524A5E3" modified="2011-12-14" version="1">MGQTLSEPVVEKASARGEDDRFLYGVSAMQGWRISMEDAHTTVLDLLANDAEAAKQHKGKLAFFGVFDGHGGDKVALFSGDNIHKIVQNQDTFKSGNYEQALKDGFLATDRAILNDPKYEDEVSGCTACVGLLTDDKIYIANAGDSRSVLGVKGRAKPLSFDHKPQNEGEKARITAAGGFVDFGRVNGNLALSRAIGDFEFKKSAELAPEQQIVTAYPDVVVHDMGDDDEFLVIACDGIWDCQSSQAVVEFVRRGIAAKQALEKICENMMDNCLASNSETGGVGCDNMTMIIIGFLRGRTKEEWYEEIARRVANGDGPCAPPEYAEFRGPGVHHNFDDSDSGYDVDMDQSKGKTFGIGGYKGRVIFLGDGTEVLTDADDNAMFESEKQDLDSQVAKTGSSEDDGTTEDQTNKKEGTTDGKADKGTKDASEEAEAKAENIDAAVKKDEDIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ39</accession>
    <name>G4MZ39_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15684</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714313.1">
        <property type="nucleotide sequence ID" value="XM_003714265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ39"/>
    <dbReference type="GeneID" id="12984637"/>
    <dbReference type="KEGG" id="mgr:MGG_15684"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15684"/>
    <dbReference type="HOGENOM" id="CLU_3069179_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ39"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="53" mass="6078" checksum="DF65B3E9362BEDFC" modified="2011-12-14" version="1">MCARNRTTVTSDDLYRTDLYTSLTVEITINVLYFTLGTLSVSVSWVQDPYRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ71</accession>
    <name>G4MZ71_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_08179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715151.1">
        <property type="nucleotide sequence ID" value="XM_003715103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ71"/>
    <dbReference type="GeneID" id="2678415"/>
    <dbReference type="KEGG" id="mgr:MGG_08179"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08179"/>
    <dbReference type="HOGENOM" id="CLU_541918_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ71"/>
    <dbReference type="OMA" id="MELWRRP"/>
    <dbReference type="OrthoDB" id="5229761at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="503" mass="57132" checksum="75286A7F108730FB" modified="2011-12-14" version="1">MSSQNRISAPRCGIRDIPVPQRAESSGIIRNETELRWSIYNSDADSSRLTAQGISLYQVLHRSFRTDPKLTQEVPERDRTVFALPFLALNSNHPIHDLGSLFTAGYQNINRRSPDNIPFLAYVAAKTAHLTDERREDLFEWTLDTCADPQCIPMELWRRPGLPMPLQLSQDLGPMADWCTPERLDLLKPHLTVFMRDSLCRCYEALGDFCDIEAAEIALKHMPALNKTLRLLPRMIRGQNYALHRLVCSLRCYFSEGGPKRSIPYCAMLTGESAPVTSRTARVMKLGQVFGGYSSFEITLERSDLSIFGPGGMGSGRKFSIWSGLDHFLTTHNTNKSIVIFHGLLGCDKLTDDIYDEIGEIISSVKYQDRTLSRPSRRAVDISKTIFIFTSPFAEDLIAEHKEKWYYLREIKDWQKKSPPDAADRFMSLVEFSKTPAGSACMEELIQAIRDKARSRPDSSAWQLASQVCDGGSVIPHFPMDWEDMNILVERKTQEDGWQTCFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZS4</accession>
    <name>G4MZS4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715245.1">
        <property type="nucleotide sequence ID" value="XM_003715197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZS4"/>
    <dbReference type="GeneID" id="12985597"/>
    <dbReference type="KEGG" id="mgr:MGG_15846"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15846"/>
    <dbReference type="HOGENOM" id="CLU_2038514_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZS4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="121" mass="13438" checksum="7A4B1FDB68294DBF" modified="2011-12-14" version="1">MLAGELSACFSFQNRWDGCLRSLARGFTGQKLVVFETKWVIVLASAHSNPSFAPNLWSKKVRSRKAFHRRTKKLVTMGANSSVATEVSKQFIGIGSCLRGLSSWLNWCRIAFAPAFSRPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0N5</accession>
    <name>G4N0N5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712973.1">
        <property type="nucleotide sequence ID" value="XM_003712925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0N5"/>
    <dbReference type="GeneID" id="2683688"/>
    <dbReference type="KEGG" id="mgr:MGG_07761"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07761"/>
    <dbReference type="eggNOG" id="ENOG502SZUP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1057889_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0N5"/>
    <dbReference type="OMA" id="HERNSWN"/>
    <dbReference type="OrthoDB" id="3524679at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033481">
        <property type="entry name" value="Dni1/Fig1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12351">
        <property type="entry name" value="Fig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="226" mass="24691" checksum="C7D747168D05E305" modified="2011-12-14" version="1">MANGNMFRMVTWGLTIPIVLFYVLSLVGCISNSPGIPDIFLLKLTTPETETPYQVRIGYFGLCAGSDDAKLSCLPSFSLGRAPGTTVFNTTLPAELTRLVELGHEVQVKVIFFVPLLLASVLFFVSTTTVFLWRNVPQISPMAATVAFLMHSLALGLLLAAATAVSMVVNALHFAVVEITRGQNEINVEGGKALQTFQWLTVIFSCVWQVCILKRYRSDMAGGKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2024-01-24" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1D9</accession>
    <name>G4N1D9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712217.1">
        <property type="nucleotide sequence ID" value="XM_003712169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1D9"/>
    <dbReference type="GeneID" id="12984930"/>
    <dbReference type="KEGG" id="mgr:MGG_16795"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16795"/>
    <dbReference type="InParanoid" id="G4N1D9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="59" mass="6453" checksum="E2B2DAB564730BB8" modified="2011-12-14" version="1" fragment="single">PNKLEYKAADPSAIVGLPRIIVYSHHIITTASRCDSGCAVGWEHENAAIIVHKCQQARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1P0</accession>
    <name>G4N1P0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Averantin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_07507</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711419.1">
        <property type="nucleotide sequence ID" value="XM_003711371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1P0"/>
    <dbReference type="STRING" id="242507.G4N1P0"/>
    <dbReference type="GeneID" id="2683427"/>
    <dbReference type="KEGG" id="mgr:MGG_07507"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07507"/>
    <dbReference type="eggNOG" id="KOG0159">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="InParanoid" id="G4N1P0"/>
    <dbReference type="OMA" id="CYYLQFR"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF29">
        <property type="entry name" value="BENZOATE-PARA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA51612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="508" mass="56932" checksum="BA8E91DA67D7FD3E" modified="2011-12-14" version="1">MTVLELPSERLASPPIAVLTAALIVLAVVFKAVYNIFFHPLRSYPGPLLWGASRFPYVVRFMQGKIPYDLKRLHAEYGPVVRIAPDELTYNCSKAWRDIYGRNKQPNGETTLFNKDPILYSAVFADHKALIDSDGDEHRPQKRTLSYAFSHQVLVERGHIITGCIDRMIEGVKAHLGSSPSVSAVVDICPWIENALFDLGGQLTVGRDLNAIMSQGTVHPSLALFKSLFDLVQCYYLQLRRGPGILINAVESMPGFSGYDCVLPVKDVHDMILKRMADEKYAVADENSGDFASYLMSRAKSEGLNDDKVWINCVHLILGTPEAMPSSIISTIYHLLTTPYAYAEAVREVRAAFKSSDEITAQDVQNLPYLLACFRETLRRRPTIPGTLTRQCGKFVQGGTIVGVNQFATSRSASNFHDADSYRPERWLDPRPAEFEGDDRDAFNPFGYGPRKCIARNLAHLTTQTFLAKLLWEFDMELDESCRDWDDQGLYVLALRGPLLVKLSRAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N235</accession>
    <name>G4N235_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711458.1">
        <property type="nucleotide sequence ID" value="XM_003711410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N235"/>
    <dbReference type="SMR" id="G4N235"/>
    <dbReference type="GeneID" id="2683464"/>
    <dbReference type="KEGG" id="mgr:MGG_07544"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07544"/>
    <dbReference type="HOGENOM" id="CLU_1540363_0_0_1"/>
    <dbReference type="InParanoid" id="G4N235"/>
    <dbReference type="OrthoDB" id="5232815at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="174" mass="19382" checksum="8F39EDF79EC40F35" modified="2011-12-14" version="1">MDGVTGGAIAMIILMVLRIIWDFCGMCAHPRRANIQDPSNIEMQDMSGRERPTSAQQDAPMDGSAQPEARTNTYRPDSFDWSKFMQMHNVTPLPAASVPSNRSATKTKTKAKDKDKDKGKGKAKEQLVAPPPRVFDWTGTNAISDEELENAGEGSSRGVPRRSRYRNSHYNNWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2W2</accession>
    <name>G4N2W2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="17">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">MGG_07971</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="function">
        <text evidence="16">This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Membrane</location>
            <topology evidence="17">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="17"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713218.1">
        <property type="nucleotide sequence ID" value="XM_003713170.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N2W2"/>
    <dbReference type="FunCoup" id="G4N2W2">
        <property type="interactions" value="452"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N2W2"/>
    <dbReference type="GeneID" id="2683898"/>
    <dbReference type="KEGG" id="mgr:MGG_07971"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07971"/>
    <dbReference type="eggNOG" id="KOG0204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_9_3_1"/>
    <dbReference type="InParanoid" id="G4N2W2"/>
    <dbReference type="OMA" id="MWIAFND"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="PHI-base" id="PHI:2099"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000028">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000018">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 17" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 17" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 17" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="429"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="963"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1043"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1075"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="21">
        <location>
            <begin position="144"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="19">
        <location>
            <begin position="241"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="20">
        <location>
            <begin position="921"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1236"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00059328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EHA53411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1286" mass="140453" checksum="9BEA8BAD7D10D08F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4N370</accession>
    <name>G4N370_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712433.1">
        <property type="nucleotide sequence ID" value="XM_003712385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N370"/>
    <dbReference type="GeneID" id="12985026"/>
    <dbReference type="KEGG" id="mgr:MGG_15117"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15117"/>
    <dbReference type="HOGENOM" id="CLU_2278022_0_0_1"/>
    <dbReference type="InParanoid" id="G4N370"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="102" mass="11177" checksum="6342A1197576B5F8" modified="2011-12-14" version="1">MDPLSIAAFDKDICVKFATSSRRSSWCWTPLAARNPSNQVEDDEDEDDVDVMPVHSQLAKSIGPSLLSCQREPDHLEESLAPPRIVRNTPGSKSKVVALQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3I2</accession>
    <name>G4N3I2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_04968</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712464.1">
        <property type="nucleotide sequence ID" value="XM_003712416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3I2"/>
    <dbReference type="SMR" id="G4N3I2"/>
    <dbReference type="STRING" id="242507.G4N3I2"/>
    <dbReference type="GeneID" id="2675378"/>
    <dbReference type="KEGG" id="mgr:MGG_04968"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04968"/>
    <dbReference type="eggNOG" id="KOG1485">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013430_2_0_1"/>
    <dbReference type="InParanoid" id="G4N3I2"/>
    <dbReference type="OMA" id="QKVDTCR"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000001">
        <property type="entry name" value="Metal tolerance protein 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000005">
        <property type="entry name" value="Putative Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF13">
        <property type="entry name" value="CATION EFFLUX PROTEIN CYTOPLASMIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="9">
        <location>
            <begin position="144"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="10">
        <location>
            <begin position="343"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA52657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="460" mass="51082" checksum="920932389D6CD0E3" modified="2011-12-14" version="1">MSDRESGKPSSSAPVSLPENGAGATVGSSAQPATNIESSAVREKKELATADTSSVEASEVQNATRAETSGISADPLNFGQHRRANVSKKQMKIDHPKGNKKKLKKFYTRQNQLIDQFLGVDDEEQNAIEEDARVAPKIKFAVNASFVVNFCLFIIQLYAAISTGSLALFATAADAFMDLVSSFVMLVTSRMAARPSIYKYPVGRTRIETIGVILFCALMTTVAIQLLVESGRNLGAGGHESGELHIIPIVFVGVAIFAKGSLMVFCLFYRKYPSVHVFYIDHRNDIAVNSFGLIMAVAGEKFVWYLDPIGAILIALIILFSWVTNAFEQVWLLVGKSAPREFISKLIYMAMTHDEQILKVDTCRAYHAGQRYYVEVDVVMDDETPLRISHDVAQSLQRKMEGLGDVERAFVHVDYEHEHDVHEEHKPLYVREPKTKRTWKEIFTGAKKKVQGENPDSQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3Z2</accession>
    <name>G4N3Z2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711721.1">
        <property type="nucleotide sequence ID" value="XM_003711673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3Z2"/>
    <dbReference type="GeneID" id="2684079"/>
    <dbReference type="KEGG" id="mgr:MGG_05896"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05896"/>
    <dbReference type="HOGENOM" id="CLU_2278021_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3Z2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="102" mass="11454" checksum="BF856B8077EEC85A" modified="2011-12-14" version="1">MKLATGFLPYIGIALSASTSTKVKLDNRKEPALCHVVIVKPAQIRHPLDTWVETFAWVKAGKVVEWHSPKYGSVKVKTDEDDCHLTFLVNELINGYTCQLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N413</accession>
    <name>G4N413_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_05914</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711742.1">
        <property type="nucleotide sequence ID" value="XM_003711694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N413"/>
    <dbReference type="SMR" id="G4N413"/>
    <dbReference type="STRING" id="242507.G4N413"/>
    <dbReference type="GeneID" id="2684061"/>
    <dbReference type="KEGG" id="mgr:MGG_05914"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05914"/>
    <dbReference type="eggNOG" id="ENOG502QV06">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035914_2_0_1"/>
    <dbReference type="InParanoid" id="G4N413"/>
    <dbReference type="OMA" id="PNCIRRD"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466093" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA51935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="339" mass="38490" checksum="08826275031000BB" modified="2011-12-14" version="1">MHLLSLLPISLLSFLATAQGYGQCSRPITRREWRTLSSGEQQDYIEAVQCLMEKPPRSSIPAAISRYDDFVGTHIVQADETHFVGIFYPFHRLLVASFEQTLRRDCGYAGAQPYWDWTLDLDDLEGSPIFDPDTGFGGNGDWVDGTLDNPEWGVPVVAHQDFDDRSGGGCIPNGPFQGIVTSMGPNRNIERQRARCIRRDFAPETFRDRCNVEESMDQDFFVGFHRASESMAHASGHYGIGGLYGAMTDKWASPADPIFWLHHSNVDRLWWSWQMRDIQNRLTDISGPLVAHDWTNWKGGNISLEYRVKLSAIGDEAPIFDLMDIQGSYLCYDFDELYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N440</accession>
    <name>G4N440_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_16853</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712567.1">
        <property type="nucleotide sequence ID" value="XM_003712519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N440"/>
    <dbReference type="SMR" id="G4N440"/>
    <dbReference type="STRING" id="242507.G4N440"/>
    <dbReference type="GeneID" id="12985100"/>
    <dbReference type="KEGG" id="mgr:MGG_16853"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16853"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_3_1"/>
    <dbReference type="InParanoid" id="G4N440"/>
    <dbReference type="OMA" id="TQKHGER"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF138">
        <property type="entry name" value="DEHYDROGENASE PKFF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465764" description="Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="560"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="604"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="559"/>
            <end position="560"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="605"/>
            <end position="606"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="InParanoid" id="G4N491"/>
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR35711">
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4G0</accession>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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                <person name="Butler J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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    </reference>
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    <dbReference type="InParanoid" id="G4N4G0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="127" mass="14470" checksum="4383EA33E840D970" modified="2011-12-14" version="1">MAKLLGKVLLEDLVDEDVLEVLVVEELVWDDEMLAALEDDDVLVALEDDEVLAALEDDEVLVVLYVEELEDEVGAELDDEDVLVEATLAARLRVVELEEELEEELEEELEEELEEELEEESLRTNLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4L0</accession>
    <name>G4N4L0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lipid phosphate phosphatase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_05988</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711832.1">
        <property type="nucleotide sequence ID" value="XM_003711784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4L0"/>
    <dbReference type="STRING" id="242507.G4N4L0"/>
    <dbReference type="GeneID" id="2683987"/>
    <dbReference type="KEGG" id="mgr:MGG_05988"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05988"/>
    <dbReference type="eggNOG" id="KOG3030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021458_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4L0"/>
    <dbReference type="OMA" id="KEIIPIW"/>
    <dbReference type="OrthoDB" id="10030083at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF84">
        <property type="entry name" value="PHOSPHATIDIC ACID PHOSPHATASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="136"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="375"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA52025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="412" mass="45358" checksum="3736FD88EE7247E6" modified="2011-12-14" version="1">MPLFGKRRAAKEEGSLPSTEADGHRHHKRSPAESYSMSKRPSFGQWVKHTWLDIVTMAIMGALGLGIYFAEPRPARSFAVTFSDGQVVYPQFAYPLRDEVVPIWLAAFLASMVPITIMAIMQIRVRSFWEFNNAVIGILYSLITAALFQVWVKWLIGGLRPHFLDVCDPDPAKMGNNNGEGFQRLYFRPDICRGEKKLINDALESFPSGHTTAAFAGFGYLYLYLNAKLKVFSNYHPSLWKLALTYSPILAAVLIGGALTIDEYHNWYDIFAGAAVGITMAFSSYRMTFAAIWDWRFNHIPLNRTAPFNYDSYMNAELLHAVATRKAGWGGDGLGHGHGHGHHDKHAAGMGAGHVGHHDGMGHHNGVGHHNGLGHQDGAHSAVGGHANGVPANDGFTQHRRPVGGHGGDHMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5B8</accession>
    <name>G4N5B8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712782.1">
        <property type="nucleotide sequence ID" value="XM_003712734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5B8"/>
    <dbReference type="GeneID" id="12985192"/>
    <dbReference type="KEGG" id="mgr:MGG_16892"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16892"/>
    <dbReference type="HOGENOM" id="CLU_2334006_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5B8"/>
    <dbReference type="OrthoDB" id="10466041at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013175331" evidence="1">
        <location>
            <begin position="16"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="98" mass="10828" checksum="F111E44B8BDC9C24" modified="2011-12-14" version="1">MKAAVILTLFTLASAAPGRGNKGKQAVSTSGRAKSELEPQDWENCMKECKIEKHESIVGPSLYTVCKSICQQKLGLKNTDFLNKTHQTKFAQYAVPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5J1</accession>
    <name>G4N5J1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Activating signal cointegrator 1 complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06124</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711991.1">
        <property type="nucleotide sequence ID" value="XM_003711943.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N5J1"/>
    <dbReference type="FunCoup" id="G4N5J1">
        <property type="interactions" value="611"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5J1"/>
    <dbReference type="GeneID" id="2684274"/>
    <dbReference type="KEGG" id="mgr:MGG_06124"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06124"/>
    <dbReference type="eggNOG" id="KOG0952">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000335_2_0_1"/>
    <dbReference type="InParanoid" id="G4N5J1"/>
    <dbReference type="OMA" id="MCSATEF"/>
    <dbReference type="OrthoDB" id="5575at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18020">
        <property type="entry name" value="DEXHc_ASCC3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18022">
        <property type="entry name" value="DEXHc_ASCC3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000198">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000002">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000231">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000004">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000102">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000024">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000001">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000062">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF13">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039073">
        <property type="entry name" value="BRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="301"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="530"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="1163"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="1368"/>
            <end position="1562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1998" mass="222557" checksum="B6F09FA2B63B92F6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N628</accession>
    <name>G4N628_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein BTN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06604</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the battenin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716923.1">
        <property type="nucleotide sequence ID" value="XM_003716875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N628"/>
    <dbReference type="SMR" id="G4N628"/>
    <dbReference type="FunCoup" id="G4N628">
        <property type="interactions" value="111"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N628"/>
    <dbReference type="GeneID" id="2684759"/>
    <dbReference type="KEGG" id="mgr:MGG_06604"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06604"/>
    <dbReference type="eggNOG" id="KOG3880">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029663_1_2_1"/>
    <dbReference type="InParanoid" id="G4N628"/>
    <dbReference type="OMA" id="WLCNWQV"/>
    <dbReference type="OrthoDB" id="5965864at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003492">
        <property type="entry name" value="Battenin_disease_Cln3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018460">
        <property type="entry name" value="Battenin_disease_Cln3_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981:SF0">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02487">
        <property type="entry name" value="CLN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015974">
        <property type="entry name" value="CLN3_BTN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01315">
        <property type="entry name" value="BATTENIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="472" mass="50097" checksum="774622D7AA42EEE1" modified="2011-12-14" version="1">MNRSPHSSGLLPMPGSTSASWAVYRSRLVSVFRGVDSSVLIAFWLFGLINNVLYVIILSAAQDLVGTNVPKGVVLLADVLPSFLTKLVAPYFIHRIPYYARILIFVALSSSGMLLVALTPAERGVAARLVGVVLASLSSGGGELSFLGLTHYYGPMSLAAWGSGTGGAGLAGAGLYVAMTQWFGLTVKTSLLASALLPGVMVVSFFVILPRAPLKEGQAAGVKAYSALPDRDLEDEDVEGMSAGDASASLLAPGPPGVASTALHAVDAEGGGHGAAAARGAAAKPTLARNLHRAKSLFIPYMLPLLLVYVAEYTINQGVSPTLLFPLEQSPFTEFRSFYPFYGFLYQLGVFVSRSSTPFYRVHNLYLPSLLQVANLVLLTLHAVLDFIPSVYLVFAVVFWEGLLGGAVYVNTFAEIMENVPAADREFSLGATSVSDSGGICLASLIGMVLEVSLCDYQVRNGRDWCRRIEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6A5</accession>
    <name>G4N6A5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptide hydrolase</fullName>
            <ecNumber evidence="14">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_06587</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="14"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716946.1">
        <property type="nucleotide sequence ID" value="XM_003716898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6A5"/>
    <dbReference type="SMR" id="G4N6A5"/>
    <dbReference type="GeneID" id="2684742"/>
    <dbReference type="KEGG" id="mgr:MGG_06587"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06587"/>
    <dbReference type="eggNOG" id="KOG2195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025866_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6A5"/>
    <dbReference type="OMA" id="YEESTCG"/>
    <dbReference type="OrthoDB" id="2214at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03879">
        <property type="entry name" value="M28_AAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 16" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005132184" description="Peptide hydrolase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="176"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA50627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="389" mass="43554" checksum="2FC8528F7914492F" modified="2011-12-14" version="1">MKVTSALLTALAVATVNACGVPPTSLPRTAARTIFRRADAKMYTLETAPGVTIEVTEEEKLAMMDNRVHFFDITEWKEAPNAMAEDLQKRIAAVPYPKTLTQKCNATKLIGKLDKERIQATVERYSSFFNRYYMSETGRQSVEWLHDQIKAVLDAADIPGANIRLVRHNAWVQPSIVVTLPGREARTVVVGGHADSIVSGDRNGRQPGADDDASASATIFEAMRVFLMDPRVKAGQLLNTMEFHWYAAEEAGLLGSQDIFNTYRQFNRNIVAMLQQDMTGYIGRDGRERFGLITDFTDPDLVNFMKLVIDGYTDIPYEESLCGYACSDHGSATRAGYPSTFVFETPFGNHNPYIHTINDTTDKLSYDHMIQHGKLITGYLSELAWWPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6F1</accession>
    <name>G4N6F1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716140.1">
        <property type="nucleotide sequence ID" value="XM_003716092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6F1"/>
    <dbReference type="STRING" id="242507.G4N6F1"/>
    <dbReference type="GeneID" id="2676790"/>
    <dbReference type="KEGG" id="mgr:MGG_03739"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03739"/>
    <dbReference type="eggNOG" id="ENOG502RAX3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_284833_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6F1"/>
    <dbReference type="OMA" id="RFEFRDS"/>
    <dbReference type="OrthoDB" id="5353066at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="810"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="871"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="921"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="940" mass="102493" checksum="F2D979D1FD13A96A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2014-02-19" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N708</accession>
    <accession>Q3MSM7</accession>
    <name>XYL1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>NAD(P)H-dependent D-xylose reductase XYR1</fullName>
            <shortName>XR</shortName>
            <ecNumber>1.1.1.307</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">XYR1</name>
        <name type="ORF">MGG_03648</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2013" name="FEBS Lett." volume="587" first="1346" last="1352">
            <title>The pentose catabolic pathway of the rice-blast fungus Magnaporthe oryzae involves a novel pentose reductase restricted to few fungal species.</title>
            <authorList>
                <person name="Klaubauf S."/>
                <person name="Ribot C."/>
                <person name="Melayah D."/>
                <person name="Lagorce A."/>
                <person name="Lebrun M.H."/>
                <person name="de Vries R.P."/>
            </authorList>
            <dbReference type="PubMed" id="23499935"/>
            <dbReference type="DOI" id="10.1016/j.febslet.2013.03.003"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [MRNA]</scope>
        <scope>INDUCTION</scope>
        <source>
            <strain>P1.2</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>xylitol + NAD(+) = D-xylose + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27441"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17151"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.307"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>xylitol + NADP(+) = D-xylose + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27445"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17151"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.307"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text>Carbohydrate metabolism; D-xylose degradation.</text>
    </comment>
    <comment type="induction">
        <text evidence="2">Overexpressed during growth on both D-xylose or L-arabinose compared to D-glucose. Significantly expressed during late stages of infection of barley leaves.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.307"/>
    <dbReference type="EMBL" id="AJ890447">
        <property type="protein sequence ID" value="CAI67591.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716240.1">
        <property type="nucleotide sequence ID" value="XM_003716192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N708"/>
    <dbReference type="SMR" id="G4N708"/>
    <dbReference type="FunCoup" id="G4N708">
        <property type="interactions" value="411"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N708"/>
    <dbReference type="EnsemblFungi" id="MGG_03648T0">
        <property type="protein sequence ID" value="MGG_03648T0"/>
        <property type="gene ID" value="MGG_03648"/>
    </dbReference>
    <dbReference type="GeneID" id="2676633"/>
    <dbReference type="KEGG" id="mgr:MGG_03648"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03648"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_0_1"/>
    <dbReference type="InParanoid" id="G4N708"/>
    <dbReference type="OMA" id="DMYLVHT"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="UniPathway" id="UPA00810"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032866">
        <property type="term" value="F:D-xylose reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042843">
        <property type="term" value="P:D-xylose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd19115">
        <property type="entry name" value="AKR_AKR2D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000007">
        <property type="entry name" value="NAD(P)H-dependent D-xylose reductase xyl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044487">
        <property type="entry name" value="AKR2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0859">Xylose metabolism</keyword>
    <feature type="chain" id="PRO_0000425415" description="NAD(P)H-dependent D-xylose reductase XYR1">
        <location>
            <begin position="1"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="168"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="23499935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="324" mass="36631" checksum="EA7067EE14977862" modified="2011-12-14" version="1">MASPTMKLNNGLDMPQVGFGLWKVENSVCADVVYNAIKAGYRLFDGACDYGNEVECGQGVKRAIDEGLVKREELFIVSKLWNTFHDGERVEPIVKKQLADWGIEYFDLYLIHFPVALEYVDPSVRYPPGWHYDDAGTEIRPSKASIQETWTAMEKLVDAGLSKAIGVSNFQAQLLYDMLRYARIRPATLQIEHHPYLVQQRLIEACKTEGIVVTAYSSFGPASFKEFNMEHAEALTPLLEEPTIVKLAEKYGKDPGQVLLRWATQRGLAVIPKSSREKTMKSNFEAVGWDMEDSDIKTISALDKGIRFNQPANYFSTDKLWIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N742</accession>
    <name>G4N742_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716274.1">
        <property type="nucleotide sequence ID" value="XM_003716226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N742"/>
    <dbReference type="GeneID" id="12984391"/>
    <dbReference type="KEGG" id="mgr:MGG_17059"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17059"/>
    <dbReference type="HOGENOM" id="CLU_2886267_0_0_1"/>
    <dbReference type="InParanoid" id="G4N742"/>
    <dbReference type="OrthoDB" id="10351213at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="63" mass="6967" checksum="52408CB40CDCE16E" modified="2011-12-14" version="1">MEWVQRQLSVAQFAPANPGICAEMVNQISSKLQFCYDLRPKSILASCAQNQTNQACSGAYRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N798</accession>
    <name>G4N798_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_06441</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717127.1">
        <property type="nucleotide sequence ID" value="XM_003717079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N798"/>
    <dbReference type="SMR" id="G4N798"/>
    <dbReference type="STRING" id="242507.G4N798"/>
    <dbReference type="GeneID" id="2684596"/>
    <dbReference type="KEGG" id="mgr:MGG_06441"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06441"/>
    <dbReference type="eggNOG" id="KOG2464">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019103_2_0_1"/>
    <dbReference type="InParanoid" id="G4N798"/>
    <dbReference type="OMA" id="THAAQCK"/>
    <dbReference type="OrthoDB" id="21018at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072354">
        <property type="term" value="F:histone H3T3 kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024604">
        <property type="entry name" value="GSG2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419">
        <property type="entry name" value="INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419:SF18">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12330">
        <property type="entry name" value="Haspin_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01331">
        <property type="entry name" value="DUF3635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="150"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="93"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA50808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="549" mass="62274" checksum="E63C4D5E78E65E70" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7C3</accession>
    <name>G4N7C3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3835 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716301.1">
        <property type="nucleotide sequence ID" value="XM_003716253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7C3"/>
    <dbReference type="SMR" id="G4N7C3"/>
    <dbReference type="GeneID" id="2676686"/>
    <dbReference type="KEGG" id="mgr:MGG_03603"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03603"/>
    <dbReference type="eggNOG" id="ENOG502RP8H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030204_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7C3"/>
    <dbReference type="OMA" id="LNARGMW"/>
    <dbReference type="OrthoDB" id="21413at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:phosphatase inhibitor activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
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        <property type="entry name" value="DUF3835"/>
    </dbReference>
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        <property type="entry name" value="Prefoldin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052255">
        <property type="entry name" value="RNA_pol_II_subunit5-mediator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3"/>
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    </dbReference>
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        <property type="entry name" value="UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="561"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
    </feature>
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        </location>
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        <location>
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        </location>
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        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF12927"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA49982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="639" mass="70238" checksum="18435C16D451CF1C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7E7</accession>
    <name>G4N7E7_PYRO7</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7E7"/>
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    <dbReference type="KEGG" id="mgr:MGG_17070"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17070"/>
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    <dbReference type="InParanoid" id="G4N7E7"/>
    <dbReference type="Proteomes" id="UP000009058">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="78" mass="9102" checksum="3EFF24F5BC02593F" modified="2011-12-14" version="1">MDPEQKQSRQSSNQRRRWANMTYYVNFRFAPTLPNRLIYFTPAAVPSAKTCVTPSRTEVLMNIRPYRSAATPIDYNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4N854</accession>
    <name>G4N854_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I and III subunit RPAC2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06311</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717274.1">
        <property type="nucleotide sequence ID" value="XM_003717226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N854"/>
    <dbReference type="SMR" id="G4N854"/>
    <dbReference type="FunCoup" id="G4N854">
        <property type="interactions" value="553"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N854"/>
    <dbReference type="GeneID" id="2684466"/>
    <dbReference type="KEGG" id="mgr:MGG_06311"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06311"/>
    <dbReference type="eggNOG" id="KOG3438">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090381_3_2_1"/>
    <dbReference type="InParanoid" id="G4N854"/>
    <dbReference type="OMA" id="FTDEGHT"/>
    <dbReference type="OrthoDB" id="510325at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055029">
        <property type="term" value="C:nuclear DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07029">
        <property type="entry name" value="RNAP_I_III_AC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerases I and III subunit RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033898">
        <property type="entry name" value="RNAP_AC19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF28">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="8">
        <location>
            <begin position="60"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="149" mass="16691" checksum="FE4462FD65472F27" modified="2011-12-14" version="1">MAPNSRARQAEAEAADAVMDDAPTSAQVEDEAQDEFEEAEEEEEEEQRVKMLPGSTETAASFEFLKEGHTMGNALRYIIMKNPEVELCAYAIPHPSEHKMNLRIQTYEGTTAIEALEKGLKDLQELCDVVTDKFTIARDDFAGRMEMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8H8</accession>
    <name>G4N8H8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GMP synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717345.1">
        <property type="nucleotide sequence ID" value="XM_003717297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8H8"/>
    <dbReference type="GeneID" id="2684403"/>
    <dbReference type="KEGG" id="mgr:MGG_06248"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06248"/>
    <dbReference type="eggNOG" id="ENOG502RRXM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036511_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8H8"/>
    <dbReference type="OMA" id="MKNGWHP"/>
    <dbReference type="OrthoDB" id="3357271at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="41083" checksum="A5437484F577A71D" modified="2011-12-14" version="1">MSSDRMAGVKDVFKRGWHPEKEGTTFKQQVTGVFRRDDGERAASGHSATPISQLRDPASFAPPPKRTTNIIPPPPIAPRSSTYSSPQPQQEEAPAPVPSPQPRRANPPPAPPVRRNQTQPSPPPPRYEATSPATSGPPSLPPRLPPRSGNFSPPPPAAPQPEADPDSGVMNRGAVSRLGAAGISVPGLGIGSSSKISSTASPSDRPSSGLSSSISGLSSRFGKLSTSSSSSSSPALSSNDPASATTAPSAASAGGGTTFAQKQAAFKTASNFRKDPSSVSLADARAAASTANNFRQRHGEQVAAGLKTANGLNEKYGIADKVSSYQQQHQPQQPGGGAQAAGSPGGGSASSLASTASMAAGFLAKKKPPPPPPPKKKPTIAAAAATSGGDADMPPPIPMSTRPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N924</accession>
    <name>G4N924_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD dependent epimerase/dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_10067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717438.1">
        <property type="nucleotide sequence ID" value="XM_003717390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N924"/>
    <dbReference type="SMR" id="G4N924"/>
    <dbReference type="STRING" id="242507.G4N924"/>
    <dbReference type="GeneID" id="2681678"/>
    <dbReference type="KEGG" id="mgr:MGG_10067"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10067"/>
    <dbReference type="eggNOG" id="ENOG502RYDN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061199_0_1_1"/>
    <dbReference type="InParanoid" id="G4N924"/>
    <dbReference type="OMA" id="TWGLRAD"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="32890" checksum="9F1667C0AE43049D" modified="2011-12-14" version="1">MAEIIPTSNEEHSIKPVQILSMGMLRTGSASITKALTILGYKNVHHGISAIADRQKFALFSAAADAHFSTLPTYTGQPFSRADWDALFGDCEAVTDMGSFFAPQLIAAYPDARVILVERDVDRWLESTDVAIFQTTWGWRSWFVADVLGRMMGLTGHLTIRKLLLGFFEARNVSEVRAHAKARYLRHNAEVRAAVEPERLLVFDLEDGWEPLCRFLGKDVPDVPFPVVNERKEHVERVRRKQKAFVGVVLGRFARSAIPWALGVGAIAVCVVCLDTGKKCWVSRAAAAALRLRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9F3</accession>
    <name>G4N9F3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03298</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716664.1">
        <property type="nucleotide sequence ID" value="XM_003716616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9F3"/>
    <dbReference type="SMR" id="G4N9F3"/>
    <dbReference type="GeneID" id="2676932"/>
    <dbReference type="KEGG" id="mgr:MGG_03298"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03298"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="InParanoid" id="G4N9F3"/>
    <dbReference type="OMA" id="CNKQADR"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000409">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000511">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF47">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="51"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="493" mass="54733" checksum="9BC14C17F745CC0E" modified="2011-12-14" version="1">MSDLEKEKPQGIEAEQAASIESPTTTRPRPEDFNFTPEEQKKIKRRMDLRIVTTLGFMYCVSLMDRTNLGAASIAGMDRELRLDVGDRYSIITLVFFITYTLFQPPSTVIVRAVGPRVHLALITLLWGAVMIGMGFAPDWGAMAGLRVLLGILEAGFFPSCVYLLSTWYTRYEVGRRYSVFYLIGCVASAFSGILAFGLMQMAGLGNLNGWRWIFIIEGIITCLLGISGYWLLVNFPDSTRSNWSFLGERERAWIVAKIDADRGDVKTQPFSWKKWLGGGADIKIWMYAFIFFNSTTITYSLAYFMPIILNLSLGFDVGTSQCLVAPPYVFAGIIMFTGAALGDKYHVRGPIIVFNMLLCVIGLPILGFHTDAKVRYFGIFLCTAGANANIPAVMSYQANNIRGQWKRAFCSATLVAMGGIGGIAGSLVFRNQDKPGYRPGLYACITCAICNILCVGILTLLFKRENDKADKEGKQLECSAGDDFQPGFRYTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9I1</accession>
    <name>G4N9I1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Alpha-mannosidase</fullName>
            <ecNumber evidence="3">3.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_12735</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Degrades free oligosaccharides in the vacuole.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 38 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.24" evidence="3"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716692.1">
        <property type="nucleotide sequence ID" value="XM_003716644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9I1"/>
    <dbReference type="SMR" id="G4N9I1"/>
    <dbReference type="FunCoup" id="G4N9I1">
        <property type="interactions" value="235"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9I1"/>
    <dbReference type="GeneID" id="5050111"/>
    <dbReference type="KEGG" id="mgr:MGG_12735"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12735"/>
    <dbReference type="eggNOG" id="KOG4342">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003442_0_1_1"/>
    <dbReference type="InParanoid" id="G4N9I1"/>
    <dbReference type="OMA" id="WHERERF"/>
    <dbReference type="OrthoDB" id="10261055at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009313">
        <property type="term" value="P:oligosaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.50:FF:000004">
        <property type="entry name" value="alpha-mannosidase 2C1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.110.10:FF:000002">
        <property type="entry name" value="alpha-mannosidase 2C1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.30:FF:000001">
        <property type="entry name" value="alpha-mannosidase 2C1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="entry name" value="Glycoside hydrolase 38, N terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.50">
        <property type="entry name" value="Glycoside hydrolase family 38, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054723">
        <property type="entry name" value="Ams1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041147">
        <property type="entry name" value="GH38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011682">
        <property type="entry name" value="Glyco_hydro_38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015341">
        <property type="entry name" value="Glyco_hydro_38_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037094">
        <property type="entry name" value="Glyco_hydro_38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46017">
        <property type="entry name" value="ALPHA-MANNOSIDASE 2C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46017:SF1">
        <property type="entry name" value="ALPHA-MANNOSIDASE 2C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09261">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22907">
        <property type="entry name" value="Ams1-like_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17677">
        <property type="entry name" value="Glyco_hydro38C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07748">
        <property type="entry name" value="Glyco_hydro_38C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00872">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="Families 57/38 glycoside transferase middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 38 central" evidence="9">
        <location>
            <begin position="570"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00071615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA50373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1100" mass="122629" checksum="1740A349C67CE769" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9J6</accession>
    <name>G4N9J6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03263</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716707.1">
        <property type="nucleotide sequence ID" value="XM_003716659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9J6"/>
    <dbReference type="SMR" id="G4N9J6"/>
    <dbReference type="STRING" id="242507.G4N9J6"/>
    <dbReference type="GeneID" id="2676852"/>
    <dbReference type="KEGG" id="mgr:MGG_03263"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03263"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9J6"/>
    <dbReference type="OMA" id="LWTDEVF"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07106">
        <property type="entry name" value="ALDH_AldA-AAD23400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044086">
        <property type="entry name" value="LUC3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="32"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA50388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="485" mass="52027" checksum="89F0C126A278AD9E" modified="2011-12-14" version="1">MATKGSEGFATHEFFNIINGQRRGAGAGGVDRVIDPRTEEPLWEVPIGSAEDLEDAVTAARAALPGWAATTAEERQQLLAKMAEALGANMEFLAGVVMKETGKSQLMATIEIANSLDQCKYFANNTLQDKVQFEDDTIKIIETHAPLGVVGAISPWNFPLILSSIKVVSALVMGNTVIMKPSPFTPYCVLKFAELCQSFLPPGVLQAINGGGELGGLMTLHDGIDKISFTGSIPTGKKVMANCAKTLKRVTLELGGNDAALVCANVDLDKVVAQTCAGSFFNAGQFCAATKRIYVHADIYDAFVDKFVAETKANYESAFAGDGVSVPTIFGPVSNKMQFDVVKRILDDAARPESGGKILTGGKPHDKGYWIQPTVVAGPKEDSMVVKDEQFGPVIPILKWSDEQDVIKRANLSNSGLGATVYSKDLTQAERIARQLESGSVWINMSEKPNAAAWFGGWKDSGFGGEMGLLGLYSYCHIKSIHFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9Q1</accession>
    <name>G4N9Q1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717558.1">
        <property type="nucleotide sequence ID" value="XM_003717510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9Q1"/>
    <dbReference type="SMR" id="G4N9Q1"/>
    <dbReference type="GeneID" id="2680732"/>
    <dbReference type="KEGG" id="mgr:MGG_09785"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09785"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_8_2_1"/>
    <dbReference type="InParanoid" id="G4N9Q1"/>
    <dbReference type="OMA" id="WGDFESN"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF8">
        <property type="entry name" value="7ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="300" mass="32310" checksum="814893909CEAEB56" modified="2011-12-14" version="1">MSLPSLKKYHKGPYPAISPTLPQLVQSGKTVIVSGGSSGIGYAIARSFVAAGAARVIVLGRRQKVVESAATTLNKEAGRQAAEGRAVDAYSLPAIEALWSSLHAQGIYVHVLVLSAAAFGSKSPILANTVEDTWKDFEANVRAPLAMTVVFSNQKTGNERRFLVNISSIAAYMWSTMGPDRPTYGLTKNAGTALFQQIAKDTDPNNMQVVSFHPGGVLTESARTEGYAESGFDFDDENLSGNFAVWAASPEATFLHGRFVWANWDVLEMKDIIGPRVKEDEHFLKVGIEGLSEKNGGARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAJ3</accession>
    <name>G4NAJ3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717650.1">
        <property type="nucleotide sequence ID" value="XM_003717602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAJ3"/>
    <dbReference type="SMR" id="G4NAJ3"/>
    <dbReference type="GeneID" id="12986591"/>
    <dbReference type="KEGG" id="mgr:MGG_17280"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17280"/>
    <dbReference type="HOGENOM" id="CLU_2097340_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAJ3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="116" mass="13149" checksum="42E42A5EFC13CE26" modified="2011-12-14" version="1">MDIGNWSRLWNLGLERSDYRLVAGDGQSLVEEVETLRDKVSRVPIRHSLARKAKHISSGASHFDRYACLDLEKLSGQTPAKAMGRSRAHYEEAKAARTDSAGQGERERWKLWPKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB69</accession>
    <name>G4NB69_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming)</fullName>
            <ecNumber evidence="3">1.1.1.179</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">D-xylose-NADP dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_11542</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22000"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15867"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.179" evidence="3"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718415.1">
        <property type="nucleotide sequence ID" value="XM_003718367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB69"/>
    <dbReference type="STRING" id="242507.G4NB69"/>
    <dbReference type="GeneID" id="5050699"/>
    <dbReference type="KEGG" id="mgr:MGG_11542"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11542"/>
    <dbReference type="eggNOG" id="KOG2741">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_5_2_1"/>
    <dbReference type="InParanoid" id="G4NB69"/>
    <dbReference type="OMA" id="GEDWWMS"/>
    <dbReference type="OrthoDB" id="6417021at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047837">
        <property type="term" value="F:D-xylose 1-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF105">
        <property type="entry name" value="TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="28"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="7">
        <location>
            <begin position="173"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="426" mass="47080" checksum="05E1C8648FD2AC92" modified="2011-12-14" version="1">MSGVFGFVNRNWVLVAGPTPVPKNDNALKFGILGAAKIAPMALIGPAQTHAGVVIQAVAARDKKKAVAYAKKHGIPQVMDSYQAILDDPSIDCIYNPLPNGLHYEWTLRALAAGKHVLLEKPSTATAAEAEILFNHPLLQQKPKAPVLMEAVHYRLHPAWSLFMSFVDPPNVVHAQAITKFPRFLFADDDIRFTYSLGGGATLDLGTYGASAVRIIFGGALPVECTTAHMKPCPAPREKCDEAVKATFRFANGGTADIEATLRGTLAELVDVSPRVWATHRPVEVPDATLPENQEKIRTRKVYMANFMGPSIWHRIDVEDDYVIRERAPGGIEGPHDESRRTVKSWSEKKSVKGYTWADVGAEGRGDAPQWMTYRHMLDQFVNRVRGDQGSGLWIEHEDSVIQARMLDMMYEKSGLGLRETSTFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBA5</accession>
    <name>G4NBA5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Coiled-coil domain-containing protein 130</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718451.1">
        <property type="nucleotide sequence ID" value="XM_003718403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBA5"/>
    <dbReference type="SMR" id="G4NBA5"/>
    <dbReference type="STRING" id="242507.G4NBA5"/>
    <dbReference type="GeneID" id="2675166"/>
    <dbReference type="KEGG" id="mgr:MGG_00589"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00589"/>
    <dbReference type="eggNOG" id="KOG2990">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050402_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBA5"/>
    <dbReference type="OMA" id="AEMAMSK"/>
    <dbReference type="OrthoDB" id="360327at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="401" mass="43951" checksum="0701A3F79A11F1EC" modified="2011-12-14" version="1">MQGFNMGRYVPPDVEGTITGNKLHGKHPQGSRARHGGGALTVRFEMPFPVWCEGCPQETLIGQGVRFNAIKRRVGNYHSTPIFSFAIKHPACGGDIEIRTDPQNTDYVVVSGGRRREPGMRSQEGESLVSAADLARASLASIDEARGEVKDEKAREAAFAKLEKTIADRAALARSTSRVEELVDVSARAWDDPYSRNSELRNAFRAGRKEREAIAVSDEALKDKMSLGDQVVLGPETDYDRRLAALMDYGSTDGARDGARDAAEMAMSKPLFGESGRSASPAQYSKPKEKGKIADTGETPRREKPRMLKAEISKEKTREGLIGAIAMNQRTATDPFLEGLWSEKSKRQRIIPGLKRKRDPLADSSSDEATRTSAHPPKPPQQVLARTASPALVSYDSDQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBF7</accession>
    <name>G4NBF7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acid phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_00552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718498.1">
        <property type="nucleotide sequence ID" value="XM_003718450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBF7"/>
    <dbReference type="SMR" id="G4NBF7"/>
    <dbReference type="STRING" id="242507.G4NBF7"/>
    <dbReference type="GeneID" id="2674464"/>
    <dbReference type="KEGG" id="mgr:MGG_00552"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00552"/>
    <dbReference type="eggNOG" id="ENOG502QSRP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027977_2_0_1"/>
    <dbReference type="InParanoid" id="G4NBF7"/>
    <dbReference type="OMA" id="RGISWGH"/>
    <dbReference type="OrthoDB" id="5135119at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000064">
        <property type="entry name" value="Probable acid phosphatase Pho610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF8">
        <property type="entry name" value="ACID PHOSPHATASE PHOA (AFU_ORTHOLOGUE AFUA_1G03570)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466412" evidence="3">
        <location>
            <begin position="20"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="463" mass="50764" checksum="B2E4B220BCA79EF0" modified="2011-12-14" version="1">MRLYVAATALASLLAPATADHTGPPVVEKGRPAQKEISPSLQEIIATQAIAKVSSPTSDVKGVAFDRIVQIWLENTNFQAAAGDENFKWVASQGILLENYFAVTHPSQPNYAASISGDTFGLESGDFYRFPENISTVVDLLDTKKISWGAYQEDMPYAGFQGFNFSNQKTFANAYMRKHNPLILFDNIANNPDRASQIKNFTSFEEDLEKKQLPQWSFITPNTDDGHDSNYKVAARWTKSFLEPLLKNEYFMNRTLIILTFDESEVYTIQNRVFTVLMGGAVDEKLRGTNDSMFYNHYSTLATVSANWGLPSLGRWDCGSNILSMVANKTGYKNVMPDLPKLFFNETYPGPASQKRYTPGWWPVPDTTSSCSHGNGVLASVKDTWKNLPGPAYNYSDAFPYDQRTNLNTAAPAIKGSMSVVGPVAEGSSGSSSGQKKNGGASSAVGRTTVCLGASALLLTLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBK5</accession>
    <name>G4NBK5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysR family regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_10756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717694.1">
        <property type="nucleotide sequence ID" value="XM_003717646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBK5"/>
    <dbReference type="GeneID" id="2676291"/>
    <dbReference type="KEGG" id="mgr:MGG_10756"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10756"/>
    <dbReference type="eggNOG" id="ENOG502S6KB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029797_2_1_1"/>
    <dbReference type="InParanoid" id="G4NBK5"/>
    <dbReference type="OMA" id="HITSFND"/>
    <dbReference type="OrthoDB" id="21502at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="479" mass="53410" checksum="8824834EABA5F1D0" modified="2011-12-14" version="1">MKSLLKHMGPRRVTNVPTDDVFQLNAIDRVGAISNMMGWTMLKFDQVLDPVKLQETLVSLIKTGDWRKLGGRLRRNEKGHLVIRVPKEFTEQRPAVGFSHAVYYCRVQDHELGRQLPTYEPEEINLAPSPTKFHEFAQPSGVPKCLDDYLRSDLPQLWLHIVSFEDATLTCLTWPHATMDGAGLSELLTAWAYTLAGLSNQVPPCLSLRHDLLNDLISDAPDRVPIKEEIFFDSNKIVQFALMRIMWLVMLIIRALFAEKQELRNIWVPKRVIDKIRQGSLSALEAADEQGNAGSGGPVKNGKKRAHDAFIPGDLVPDRESGRPFISESDAIIAFFTRAAARALPPKSRRTVNISIILNIRDRLPSLTARLPKPGVFISNLTMSVQTLLPAQAVIPKDQGDHTARTKFSSLGLTAASVRSSLHAGLTEPQFRALAKVQLKAYASRLVGLPIIGGIDCFQVTFSSLKGNISSYKQDERER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBP3</accession>
    <name>G4NBP3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718535.1">
        <property type="nucleotide sequence ID" value="XM_003718487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBP3"/>
    <dbReference type="GeneID" id="12984113"/>
    <dbReference type="KEGG" id="mgr:MGG_17438"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17438"/>
    <dbReference type="HOGENOM" id="CLU_2923106_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBP3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="61" mass="6673" checksum="AE661B13CF8B8D53" modified="2011-12-14" version="1">MAGRSTVGLEKWNAEHELEREVCLTPSIKVPDVALVKGWREGPAVTPPRHERQQAAKGGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBS1</accession>
    <name>G4NBS1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_11567</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718563.1">
        <property type="nucleotide sequence ID" value="XM_003718515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBS1"/>
    <dbReference type="STRING" id="242507.G4NBS1"/>
    <dbReference type="GeneID" id="5050723"/>
    <dbReference type="KEGG" id="mgr:MGG_11567"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11567"/>
    <dbReference type="eggNOG" id="ENOG502S1BM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053359_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBS1"/>
    <dbReference type="OMA" id="DSLPHHA"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF2">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="8">
        <location>
            <begin position="212"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA48979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="336" mass="36793" checksum="E65BEF9FE011B558" modified="2011-12-14" version="1">MSHEVSSQNPASSSLNRVDETHDDSLPHHASEPGRRPSSSGRGLRRIESREQRIGTILERGIARAQTNQSDSTTQSTTKRMEPLLGNASRQRQHHEDTSDDDGLEIGRPGRNGAAGKRRDSGSQPNYQTINAQQNQGSRISADGSTIHRRSTASNHNRRRGTSGNATRQVDREADGRQTEGESDGNGLFAWVRATMAMFMSVELDNKGSVARDHLALERTFLAWLRTSVSFASIGIAVTQLFRLNTSINSGRDRDGESGRDLAELRRLGKPLGAAFLGISILILFLGYGRYVRGQRWVMDGRFPASRGTVILVTLLTFAVMVASLAIVIVFSPGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBV7</accession>
    <name>G4NBV7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GmrSD restriction endonucleases C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717743.1">
        <property type="nucleotide sequence ID" value="XM_003717695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBV7"/>
    <dbReference type="STRING" id="242507.G4NBV7"/>
    <dbReference type="GeneID" id="2676317"/>
    <dbReference type="KEGG" id="mgr:MGG_10798"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10798"/>
    <dbReference type="eggNOG" id="ENOG502QWPZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043034_3_1_1"/>
    <dbReference type="InParanoid" id="G4NBV7"/>
    <dbReference type="OMA" id="ASYYCTY"/>
    <dbReference type="OrthoDB" id="3162605at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011089">
        <property type="entry name" value="GmrSD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24094:SF15">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24094">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07510">
        <property type="entry name" value="GmrSD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466330" description="GmrSD restriction endonucleases C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="GmrSD restriction endonucleases C-terminal" evidence="2">
        <location>
            <begin position="86"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="200" mass="21628" checksum="0D9F590B487A4A18" modified="2011-12-14" version="1">MQVATILLSAVALVSALPTPTGIPSTATAKSLLDGLTVAQPLSGTGYNRDLFPHWSTQSGTCNTREYVLKRDGSNVETNSACSAVSGTWKSPYDGATWTSASNIDIDHMVPLKNAWVSGASQWTTTQRQQFANDITRPQLWAVTNSVNRSKSDSSPDNWLPPLASFYCTYAKSWIQVKSYWALTITGAEKSALGNMLNTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBX3</accession>
    <name>G4NBX3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10973</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717759.1">
        <property type="nucleotide sequence ID" value="XM_003717711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBX3"/>
    <dbReference type="SMR" id="G4NBX3"/>
    <dbReference type="STRING" id="242507.G4NBX3"/>
    <dbReference type="GeneID" id="2677727"/>
    <dbReference type="KEGG" id="mgr:MGG_10973"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10973"/>
    <dbReference type="eggNOG" id="ENOG502S48Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092522_0_1_1"/>
    <dbReference type="InParanoid" id="G4NBX3"/>
    <dbReference type="OMA" id="AIQAMCD"/>
    <dbReference type="OrthoDB" id="5398391at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3330.10">
        <property type="entry name" value="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018020">
        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987:SF1">
        <property type="entry name" value="OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="UraD-Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase" evidence="3">
        <location>
            <begin position="39"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="203" mass="21981" checksum="41FDB1558653F758" modified="2011-12-14" version="1">MTTQGGDDTVPLPALPPQQLSTSSKVPSKLPAIAALPGLDDASLIGTLDLLFEASPDLHALAVPVARSMTFTSYRDLIESIRSTLLSVQATVHADPVARKPLLGILAAHPRLGERKQPVSDQSKAEQASLQGEAEKLATLNAEYEAKFPGMRYVVFVNGRSRDIIMENMRARIDRGDMNAEEQDAINAMCDIAHDRAIKLNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC98</accession>
    <name>G4NC98_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_01103</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717831.1">
        <property type="nucleotide sequence ID" value="XM_003717783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC98"/>
    <dbReference type="STRING" id="242507.G4NC98"/>
    <dbReference type="GeneID" id="2674270"/>
    <dbReference type="KEGG" id="mgr:MGG_01103"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01103"/>
    <dbReference type="eggNOG" id="KOG1960">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040265_0_0_1"/>
    <dbReference type="InParanoid" id="G4NC98"/>
    <dbReference type="OMA" id="NVREQYQ"/>
    <dbReference type="OrthoDB" id="397265at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22385">
        <property type="entry name" value="KH-I_KHDC4_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22386">
        <property type="entry name" value="KH-I_KHDC4_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000037">
        <property type="entry name" value="KH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000051">
        <property type="entry name" value="Putative kh domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047890">
        <property type="entry name" value="KHDC4_KH-I_first"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047889">
        <property type="entry name" value="KHDC4_KH-I_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056149">
        <property type="entry name" value="PRP5/DDX46/KHDC4_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031121">
        <property type="entry name" value="RIK/BLOM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15744">
        <property type="entry name" value="BLOM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15744:SF0">
        <property type="entry name" value="KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23469">
        <property type="entry name" value="KH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="230"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="471"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="535" mass="56383" checksum="2A6C23B4C03C490B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCD2</accession>
    <name>G4NCD2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718665.1">
        <property type="nucleotide sequence ID" value="XM_003718617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCD2"/>
    <dbReference type="GeneID" id="12984942"/>
    <dbReference type="KEGG" id="mgr:MGG_17463"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17463"/>
    <dbReference type="HOGENOM" id="CLU_2373198_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCD2"/>
    <dbReference type="OrthoDB" id="10395762at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466342" evidence="2">
        <location>
            <begin position="19"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="95" mass="9972" checksum="9226064FEE2E7759" modified="2011-12-14" version="1">MQIKWIVFQALTISLVTSVPLVAEDKAVAGRSVESSAATPSVLVARQSETDLANNPQPPPGIQDFFDRIRGKGKGKAKSERARGAAGARANGQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCH1</accession>
    <name>G4NCH1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ThiJ/PfpI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717852.1">
        <property type="nucleotide sequence ID" value="XM_003717804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCH1"/>
    <dbReference type="SMR" id="G4NCH1"/>
    <dbReference type="STRING" id="242507.G4NCH1"/>
    <dbReference type="GeneID" id="2674101"/>
    <dbReference type="KEGG" id="mgr:MGG_01085"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01085"/>
    <dbReference type="eggNOG" id="ENOG502S46I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_44_8_1"/>
    <dbReference type="InParanoid" id="G4NCH1"/>
    <dbReference type="OMA" id="THWAFIP"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466441" evidence="1">
        <location>
            <begin position="25"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="2">
        <location>
            <begin position="86"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="249" mass="26671" checksum="C769E39643A403F9" modified="2011-12-14" version="1">MMFGPQKLVAVASLVAEFAAQVTAEATPPLKYGLVMFPAVELQDGIGPIDPLQILAAKHNMTLYILAETMQPVSSQIPIGVTPFAPSILPTHTFADAPDDIQVLIVPGGPGVRDLQTSASAEAYIRATHPKLEHLITICTGSILAGRAGALDGKLATTNKSAWKSLTPSVPGVKWVAPARWIRDGNVWSSSGVLSGIDLIHAWIKVMFGDEEEQRIAGLTEYIPQTSQCDEPYTARFNITPTADKCIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND05</accession>
    <name>G4ND05_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718779.1">
        <property type="nucleotide sequence ID" value="XM_003718731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND05"/>
    <dbReference type="STRING" id="242507.G4ND05"/>
    <dbReference type="GeneID" id="5050761"/>
    <dbReference type="KEGG" id="mgr:MGG_11604"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11604"/>
    <dbReference type="eggNOG" id="ENOG502SIJ0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034964_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND05"/>
    <dbReference type="OMA" id="FGMMNVE"/>
    <dbReference type="OrthoDB" id="5279008at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="466" mass="52489" checksum="16D033D92AB2A361" modified="2011-12-14" version="1">MPKLSDMPIEILCQISRQLSTTDLGNLRLTNKRYEAAIFKPFMREFFSKKQFMLTEPSLRALIDISLHPQFAYEIKHLILGLDHYQSGVAGFGPSEDQNMEYVMGSCAQRAFLNSGTARDMLAMAVKNLPSLEVIDIRDFRSNSRTRDRGAFSSYGAPTVERSTGLPLRMSSGPADYVQLYLPSIAFSIVLQVIGSRGIGIETVIRNNHWGLTDSAFSLSEFNRAPTVAALQCMKKLHLCLDMNNNEFTSHTAQDPKDVEARRWMAKSHLQTLLSYTTNLEWLRLNLLTGDLNLQRSFLCWVGLPTQYGSPVFAAPLKRLDLGYVRIRSEEYIALFRKFKGTLEAFSIWNSSIEMNTQDVRDKVNQWGQLFKRLAVELPHLREVVVGRLRAELIYAVDIVANNGEKGGNSVEYRGDDARGFLKRLGERIVPQWPASDSESELDSEDSDGFVAGDDEENSDGETGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND17</accession>
    <name>G4ND17_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ent-kaurene oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_00300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718791.1">
        <property type="nucleotide sequence ID" value="XM_003718743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND17"/>
    <dbReference type="SMR" id="G4ND17"/>
    <dbReference type="GeneID" id="2674378"/>
    <dbReference type="KEGG" id="mgr:MGG_00300"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00300"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_3_1"/>
    <dbReference type="InParanoid" id="G4ND17"/>
    <dbReference type="OMA" id="MVNIATY"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA49207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="515" mass="58144" checksum="0C9CC75260D6984C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDT7</accession>
    <name>G4NDT7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718903.1">
        <property type="nucleotide sequence ID" value="XM_003718855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDT7"/>
    <dbReference type="GeneID" id="2674504"/>
    <dbReference type="KEGG" id="mgr:MGG_00208"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00208"/>
    <dbReference type="eggNOG" id="ENOG502S1YP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014331_1_0_1"/>
    <dbReference type="InParanoid" id="G4NDT7"/>
    <dbReference type="OMA" id="IGWAFNC"/>
    <dbReference type="OrthoDB" id="5411773at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="618" mass="68041" checksum="A0AEA43BEE87A2EC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDZ7</accession>
    <name>G4NDZ7_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718117.1">
        <property type="nucleotide sequence ID" value="XM_003718069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDZ7"/>
    <dbReference type="GeneID" id="2674973"/>
    <dbReference type="KEGG" id="mgr:MGG_00858"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00858"/>
    <dbReference type="eggNOG" id="KOG3375">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1885906_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDZ7"/>
    <dbReference type="OMA" id="NMWSEEA"/>
    <dbReference type="OrthoDB" id="5421757at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
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        <location>
            <begin position="44"/>
            <end position="58"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
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        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="143" mass="15513" checksum="AB45E687894DBDBE" modified="2011-12-14" version="1">MSGRPGGNSRGRGGKFKKFTRGGGRHFSRDLQPIDNEDYKKEEEDSEEDSEEGSSEEEQERKPRPPKKSREQLKAEKKAAKAAAAAKAKAPPKPQPGDMPPSESSEEEDDEEESEEESSEDEAKAKQAAAAAAAKKASAPVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEG6</accession>
    <name>G4NEG6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="17">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">MGG_00111</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 17">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 17">Membrane</location>
            <topology evidence="1 17">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="17"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719027.1">
        <property type="nucleotide sequence ID" value="XM_003718979.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NEG6"/>
    <dbReference type="FunCoup" id="G4NEG6">
        <property type="interactions" value="23"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NEG6"/>
    <dbReference type="GeneID" id="2674419"/>
    <dbReference type="KEGG" id="mgr:MGG_00111"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00111"/>
    <dbReference type="eggNOG" id="KOG0206">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000846_5_2_1"/>
    <dbReference type="InParanoid" id="G4NEG6"/>
    <dbReference type="OMA" id="YVYGQRN"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
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    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
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        <property type="entry name" value="ATPase_P-type_domA"/>
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        <property type="entry name" value="HAD_sf"/>
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        <property type="entry name" value="P-type_ATPase_IV"/>
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        <property type="entry name" value="P-type_ATPase_N"/>
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    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
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    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
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    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="ATPase_P-type"/>
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    <dbReference type="PANTHER" id="PTHR24092:SF174">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="CATATPASE"/>
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        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
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        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
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        <property type="entry name" value="HAD-like"/>
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        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
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        <property type="entry name" value="ATPASE_E1_E2"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="421"/>
            <end position="442"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1256"/>
            <end position="1281"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1287"/>
            <end position="1306"/>
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    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1318"/>
            <end position="1337"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1363"/>
            <end position="1386"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1406"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="86"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="19">
        <location>
            <begin position="224"/>
            <end position="298"/>
        </location>
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        <location>
            <begin position="1142"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="564"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="765"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1480"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="570"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="586"/>
            <end position="600"/>
        </location>
    </feature>
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            <begin position="765"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="808"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="1480"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="14">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
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        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <feature type="binding site" evidence="16">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
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        <location>
            <position position="663"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="711"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="734"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
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    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
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    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EHA49443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1501" mass="166854" checksum="556E4EA676D07EA5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF09</accession>
    <name>G4NF09_PYRO7</name>
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        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00032</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719112.1">
        <property type="nucleotide sequence ID" value="XM_003719064.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NF09"/>
    <dbReference type="SMR" id="G4NF09"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_00032"/>
    <dbReference type="eggNOG" id="ENOG502SQ3E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011409_13_2_1"/>
    <dbReference type="InParanoid" id="G4NF09"/>
    <dbReference type="OMA" id="DITYTFC"/>
    <dbReference type="OrthoDB" id="3145928at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
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    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052360">
        <property type="entry name" value="Transcr_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36206:SF12">
        <property type="entry name" value="ASPERCRYPTIN BIOSYNTHESIS CLUSTER-SPECIFIC TRANSCRIPTION REGULATOR ATNN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="552" mass="61132" checksum="01E58446982F2C1C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF82</accession>
    <name>G4NF82_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_04217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719597.1">
        <property type="nucleotide sequence ID" value="XM_003719549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF82"/>
    <dbReference type="SMR" id="G4NF82"/>
    <dbReference type="GeneID" id="2677443"/>
    <dbReference type="KEGG" id="mgr:MGG_04217"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04217"/>
    <dbReference type="eggNOG" id="ENOG502T08M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062065_0_0_1"/>
    <dbReference type="InParanoid" id="G4NF82"/>
    <dbReference type="OMA" id="FHEHVMY"/>
    <dbReference type="OrthoDB" id="2830113at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07366">
        <property type="entry name" value="SnoaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="35517" checksum="33874D6922493D02" modified="2011-12-14" version="1">MIENERDTMPIESAFRSFIEHVNLGRWDELAQYVPQEGRVTYNKREYHGDEFLTRMRERIGALPDGAFEVDTSMGDEEAQVVAVRIIWRTIVPDGEDMEFMPGLEGIVLSGGGSGGGRGSSATAKQRLTGVHHLFCWLKDGQVSDIETIGDVDGVFLDDDVSSTTDSTAAYVAEDTPSQFTSKADLSSNYRAYIDCINGRTMEADLPRFCHPSVWHNNRQLSLSQYRLLMEDAQRAIPDIRFDVQSLIVDESAQRLAVRLEFTGVPALKWAGVEPSGKPVAFSEHVFYWLQDGRICKVLSLVDLATYREQVRGLGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="80" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFW8</accession>
    <name>G4NFW8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Protein kinase C-like</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">MGG_08689</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 26">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719292.1">
        <property type="nucleotide sequence ID" value="XM_003719244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFW8"/>
    <dbReference type="SMR" id="G4NFW8"/>
    <dbReference type="FunCoup" id="G4NFW8">
        <property type="interactions" value="403"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NFW8"/>
    <dbReference type="GeneID" id="2679062"/>
    <dbReference type="KEGG" id="mgr:MGG_08689"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08689"/>
    <dbReference type="eggNOG" id="KOG0694">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_54_0_1"/>
    <dbReference type="InParanoid" id="G4NFW8"/>
    <dbReference type="OMA" id="QCTHLVP"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004697">
        <property type="term" value="F:diacylglycerol-dependent serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1182" mass="131967" checksum="5F7FDFCA1809F035" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG68</accession>
    <name>G4NG68_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Spermidine/putrescine import ATP-binding protein potA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_11025</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGE8</accession>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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        <property type="nucleotide sequence ID" value="XM_003719424.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_04335"/>
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
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    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF5">
        <property type="entry name" value="ENZYME, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01222)-RELATED"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47105.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="685" mass="76335" checksum="105F132F44D2F795" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGN8</accession>
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        <submittedName>
            <fullName evidence="3">Class III chitinase</fullName>
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    </protein>
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        <name evidence="3" type="ORF">MGG_04073</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003719717.1"/>
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    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
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    <dbReference type="GeneID" id="2677533"/>
    <dbReference type="KEGG" id="mgr:MGG_04073"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04073"/>
    <dbReference type="eggNOG" id="ENOG502RK0Z">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_060983_1_0_1"/>
    <dbReference type="InParanoid" id="G4NGN8"/>
    <dbReference type="OMA" id="AEDPRMY"/>
    <dbReference type="OrthoDB" id="3012298at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
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    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
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    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
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        <property type="entry name" value="ENDOCHITINASE"/>
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    <dbReference type="PANTHER" id="PTHR45708:SF60">
        <property type="entry name" value="III CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03850)-RELATED"/>
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        <property type="entry name" value="Glyco_hydro_18"/>
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        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
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        <location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="369"/>
        </location>
    </feature>
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            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="369" mass="41119" checksum="535D70ABAC6C3AA5" modified="2011-12-14" version="1">MPPIPSTPGPHLPRIITYFQTTHTRDGKPISVLPLIREPGVSVTHVIVAAIHLNEDPDAITLNDHHPGHERYQTMWAEMRILQASGVKILGMLGGHARGSYERLDADQAQFERYYAALHRMIETHALEGLDLDVEEPMSLQGIVRLIDRLRADFGPDFIITLAPVATALLGDDDPRRNLSGFGYDALHAERGHEIAWYNTQFYCGWGDCSNPVMYELIMSRGRFPADKVVVGLVTNHANGSGWVPWEMLASVLPILVGRRADFGGVMGWEYFNSLPGGEEKPWEWAMFMTALIRGDRAVAPQEQHVLESVESESQRERDERARQKKEAESQKAAAAVMEADPDDSKGGDAPVPHEFEYHSDGRETPGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGT1</accession>
    <name>G4NGT1_PYRO7</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17705</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719808.1">
        <property type="nucleotide sequence ID" value="XM_003719760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGT1"/>
    <dbReference type="GeneID" id="12986238"/>
    <dbReference type="KEGG" id="mgr:MGG_17705"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17705"/>
    <dbReference type="HOGENOM" id="CLU_1982025_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGT1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="126" mass="13818" checksum="DA4E55635C96505B" modified="2011-12-14" version="1">MEEASHLGHVFCAVPRQARQDLLCNSHFRKVDVYDDVHDYVTDCDATNTYTREVGSARNKPGERQTISKGETHFRPVNMVTPLSAVSWSRPSINPYTRALGHSGSGSGSGLLLGSLGNLEDCIVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGX8</accession>
    <name>G4NGX8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719855.1">
        <property type="nucleotide sequence ID" value="XM_003719807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGX8"/>
    <dbReference type="GeneID" id="2677247"/>
    <dbReference type="KEGG" id="mgr:MGG_03997"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03997"/>
    <dbReference type="eggNOG" id="ENOG502SFQA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021365_1_0_1"/>
    <dbReference type="InParanoid" id="G4NGX8"/>
    <dbReference type="OMA" id="WFRTPPD"/>
    <dbReference type="OrthoDB" id="5379885at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="624"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="637"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="703" mass="77057" checksum="A382A71D5E526CD4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHJ8</accession>
    <name>G4NHJ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Lovastatin nonaketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_14943</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720075.1">
        <property type="nucleotide sequence ID" value="XM_003720027.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NHJ8"/>
    <dbReference type="STRING" id="242507.G4NHJ8"/>
    <dbReference type="GeneID" id="12987146"/>
    <dbReference type="KEGG" id="mgr:MGG_14943"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14943"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_37_5_1"/>
    <dbReference type="InParanoid" id="G4NHJ8"/>
    <dbReference type="OMA" id="TILLAYC"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19532">
        <property type="entry name" value="C_PKS-NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF20">
        <property type="entry name" value="HYBRID PKS-NRPS SYNTHETASE APDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23297">
        <property type="entry name" value="ACP_SdgA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="12">
        <location>
            <begin position="8"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="13">
        <location>
            <begin position="924"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="2370"/>
            <end position="2445"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="3427"/>
            <end position="3505"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="9">
        <location>
            <begin position="924"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="9">
        <location>
            <begin position="1078"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="3006"/>
            <end position="3030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="3878"/>
            <end position="3937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="3882"/>
            <end position="3895"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="9">
        <location>
            <position position="956"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="9">
        <location>
            <position position="1134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA47708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="3972" mass="432059" checksum="9A225DE8F0328253" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIM8</accession>
    <name>G4NIM8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_09791</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720455.1">
        <property type="nucleotide sequence ID" value="XM_003720407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIM8"/>
    <dbReference type="GeneID" id="2680858"/>
    <dbReference type="KEGG" id="mgr:MGG_09791"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09791"/>
    <dbReference type="eggNOG" id="ENOG502R93K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_0_1"/>
    <dbReference type="InParanoid" id="G4NIM8"/>
    <dbReference type="OMA" id="NIAIWCL"/>
    <dbReference type="OrthoDB" id="5417887at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF42">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="40"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="227" mass="24529" checksum="174E7D1477ACC424" modified="2011-12-14" version="1">MAGDNSGPGPDGVPNIANNGLKTNIAIWCLFVLATVFLLLRLYSKGRRPRRGFWWDDYVLVFAWTCQLASVVQISVMIANGFGMPGKYLDAKQTYRVGLGGLVAGTMMILATTGSKTSFILTLVRISTGPQLTAALCIAAVSMNLCHIATILLQWLQCQPLEKAWHRLPAGTCLPSRVNLGMAMASTAYSGFIDLSLAIASWFVVSSLQIRKTERIGIALVMSMGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIQ8</accession>
    <name>G4NIQ8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_04141</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719689.1">
        <property type="nucleotide sequence ID" value="XM_003719641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIQ8"/>
    <dbReference type="GeneID" id="2677651"/>
    <dbReference type="KEGG" id="mgr:MGG_04141"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04141"/>
    <dbReference type="eggNOG" id="ENOG502SNYA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006524_8_0_1"/>
    <dbReference type="InParanoid" id="G4NIQ8"/>
    <dbReference type="OMA" id="CQYMEDV"/>
    <dbReference type="OrthoDB" id="5217604at2759"/>
    <dbReference type="PHI-base" id="PHI:5672"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF10">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="678" mass="76029" checksum="49178DF0C0C9FDD4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4NK78</accession>
    <name>G4NK78_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Homoserine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_14202</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720544.1">
        <property type="nucleotide sequence ID" value="XM_003720496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NK78"/>
    <dbReference type="SMR" id="G4NK78"/>
    <dbReference type="STRING" id="242507.G4NK78"/>
    <dbReference type="GeneID" id="5048695"/>
    <dbReference type="KEGG" id="mgr:MGG_14202"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14202"/>
    <dbReference type="eggNOG" id="ENOG502QR3J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028760_7_0_1"/>
    <dbReference type="InParanoid" id="G4NK78"/>
    <dbReference type="OMA" id="HPILVMG"/>
    <dbReference type="OrthoDB" id="444135at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001209">
        <property type="entry name" value="PRK00175.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF16">
        <property type="entry name" value="SERINE O-SUCCINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="128"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA45801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="515" mass="56237" checksum="1095F31DE5776671" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKM3</accession>
    <name>G4NKM3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Endo-1,3-beta-glucanase btgC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Laminarinase btgC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_10591</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721355.1">
        <property type="nucleotide sequence ID" value="XM_003721307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKM3"/>
    <dbReference type="SMR" id="G4NKM3"/>
    <dbReference type="STRING" id="242507.G4NKM3"/>
    <dbReference type="GeneID" id="2682204"/>
    <dbReference type="KEGG" id="mgr:MGG_10591"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10591"/>
    <dbReference type="eggNOG" id="ENOG502QTKT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011476_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKM3"/>
    <dbReference type="OMA" id="QYPDCLK"/>
    <dbReference type="OrthoDB" id="68336at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050732">
        <property type="entry name" value="Beta-glucan_modifiers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16631:SF17">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BTGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="187"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="303"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA46612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="746" mass="81993" checksum="120F1D40391DD9A7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKS0</accession>
    <name>G4NKS0_PYRO7</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03042</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720641.1">
        <property type="nucleotide sequence ID" value="XM_003720593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKS0"/>
    <dbReference type="GeneID" id="2682595"/>
    <dbReference type="KEGG" id="mgr:MGG_03042"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03042"/>
    <dbReference type="eggNOG" id="ENOG502ST1K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1797970_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKS0"/>
    <dbReference type="OrthoDB" id="5594884at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025363">
        <property type="entry name" value="DUF4267"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14087">
        <property type="entry name" value="DUF4267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466375" evidence="3">
        <location>
            <begin position="29"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA45898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="151" mass="15126" checksum="2971FDD82A16D46C" modified="2011-12-14" version="1">MASVNLITAFKAVCSIFTAASLLTGTQAIVNPTAFATSFGIPLAQPPESPKQAAASTTDTTKPPPPHHDPAASSYVALLGARQLGTGITLLVFACQGKWVECATVLSVIGLVVAGADGYHIAKNGNLGGGVFHAGPGAAIAALAAAVVWYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLU5</accession>
    <name>G4NLU5_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Mediator complex subunit 12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_02846</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SRB8-11 complex, which itself associates with the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720891.1">
        <property type="nucleotide sequence ID" value="XM_003720843.1"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NLU5"/>
    <dbReference type="GeneID" id="2682399"/>
    <dbReference type="KEGG" id="mgr:MGG_02846"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02846"/>
    <dbReference type="eggNOG" id="KOG4522">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002034_1_0_1"/>
    <dbReference type="InParanoid" id="G4NLU5"/>
    <dbReference type="OMA" id="YPVRPWE"/>
    <dbReference type="OrthoDB" id="20828at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057344">
        <property type="entry name" value="ARM_SRB8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019035">
        <property type="entry name" value="Mediator_Med12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46567">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46567:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25326">
        <property type="entry name" value="ARM_SRB8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09497">
        <property type="entry name" value="Med12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01281">
        <property type="entry name" value="Med12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med12" evidence="13">
        <location>
            <begin position="299"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="108"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA46148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1569" mass="172609" checksum="3E3503968E2B62CD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI73</accession>
    <name>G5EI73_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine-threonine kinase receptor-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGCH7_ch7g141</name>
        <name evidence="9" type="ORF">MGG_10588</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15</strain>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">70-15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721358.1">
        <property type="nucleotide sequence ID" value="XM_003721310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI73"/>
    <dbReference type="SMR" id="G5EI73"/>
    <dbReference type="STRING" id="242507.G5EI73"/>
    <dbReference type="GeneID" id="2682201"/>
    <dbReference type="KEGG" id="mgr:MGG_10588"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10588"/>
    <dbReference type="eggNOG" id="KOG0278">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_57_6_1"/>
    <dbReference type="OMA" id="DGFYGLW"/>
    <dbReference type="OrthoDB" id="408728at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF13">
        <property type="entry name" value="SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="60"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="101"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="298"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EAQ70734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA46615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="351" mass="38438" checksum="F868D16436DFB000" modified="2011-12-14" version="1">MATEAPRQYVPLTCHGHSRPVPHINFSSTFESENYFMISACKDGNPMLRQGQTGDWIGTFIGHKGAVWQAKLSPDMSNAATASADFSCKIWNSHTGEVLFTLKHEHIVRAIAYPPNTSDMVATGGFEKKLRLWDLQAASKKLAETTEEVAVESSEAHEIGAGTHTDPIKAIVWAPDPTKIITASGKTLRWFDVPTKSLVKTLVLDDEIKSCESSQLDPQFADSSDINGGSPVLAVAAGKTVVFFGGRQMNEELKRIKLTHGIASVALDLKQRKFAVGEEPGTWVRVYSYEDEKEIDVHKGHHGPVWSIAFSPDGKLYATASEDGTIKLWKNCEAFYGLWRGGANGTEKSSD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-09-13" modified="2025-02-05" version="84" xmlns="https://uniprot.org/uniprot">
    <accession>Q52E73</accession>
    <accession>A4R8M1</accession>
    <accession>G4N7A7</accession>
    <name>SPP2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Pre-mRNA-splicing factor SPP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">SPP2</name>
        <name type="ORF">MGG_06433</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in spliceosome maturation and the first step of pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SPP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717136.1">
        <property type="nucleotide sequence ID" value="XM_003717088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q52E73"/>
    <dbReference type="STRING" id="242507.Q52E73"/>
    <dbReference type="EnsemblFungi" id="MGG_06433T0">
        <property type="protein sequence ID" value="MGG_06433T0"/>
        <property type="gene ID" value="MGG_06433"/>
    </dbReference>
    <dbReference type="GeneID" id="2684588"/>
    <dbReference type="KEGG" id="mgr:MGG_06433"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06433"/>
    <dbReference type="eggNOG" id="ENOG502RZY8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047291_1_0_1"/>
    <dbReference type="InParanoid" id="Q52E73"/>
    <dbReference type="OMA" id="AWGKSAM"/>
    <dbReference type="OrthoDB" id="5577072at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045166">
        <property type="entry name" value="Spp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026822">
        <property type="entry name" value="Spp2/MOS2_G-patch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818">
        <property type="entry name" value="G PATCH AND KOW-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818:SF2">
        <property type="entry name" value="G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12656">
        <property type="entry name" value="G-patch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0508">mRNA splicing</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0747">Spliceosome</keyword>
    <feature type="chain" id="PRO_0000218525" description="Pre-mRNA-splicing factor SPP2">
        <location>
            <begin position="1"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="347" mass="38297" checksum="CF76CE2A809ABFFC" modified="2012-01-25" version="3">MSDKDPANSRIAIKFGASKAPLRPSPASALGKRARPHLLGGNASDSESDGEGRPADRAENITTIGAGADGRGRDTGSSKKPLTIPRQANRDWKSEKRARTNTTSTRQQADKEVEPVDQGKPLKWGLTLKEKGAKATEDAGGQAGEASTDQSDADKGADAKPEKTADEEAMEALLDEREDKKKRNLVIARAESAGAKEEEAFKQNFRDAPDVSTLEDYEEMPVEEFGAALLRGMGWDGKPRGPKTKDVKRRPNQMGLGAKDLKGQEDLGAWDQKGSSRSRPKRLNDYKREERERQDKRSHRGSESYKQERDRERYAAVYLGLCGRSRPSTGHRFMYGNAKISRQLMKD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-05-03" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4R0E6</accession>
    <accession>G4MRP6</accession>
    <name>UTP25_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>U3 small nucleolar RNA-associated protein 25</fullName>
            <shortName>U3 snoRNA-associated protein 25</shortName>
        </recommendedName>
        <alternativeName>
            <fullName>U three protein 25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">UTP25</name>
        <name type="ORF">MGG_10652</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UTP25 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710081.1">
        <property type="nucleotide sequence ID" value="XM_003710033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R0E6"/>
    <dbReference type="FunCoup" id="A4R0E6">
        <property type="interactions" value="1228"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4R0E6"/>
    <dbReference type="EnsemblFungi" id="MGG_10652T0">
        <property type="protein sequence ID" value="MGG_10652T0"/>
        <property type="gene ID" value="MGG_10652"/>
    </dbReference>
    <dbReference type="GeneID" id="2682265"/>
    <dbReference type="KEGG" id="mgr:MGG_10652"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10652"/>
    <dbReference type="eggNOG" id="KOG2340">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018705_0_1_1"/>
    <dbReference type="InParanoid" id="A4R0E6"/>
    <dbReference type="OMA" id="QDRGDTF"/>
    <dbReference type="OrthoDB" id="10264378at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002356">
        <property type="entry name" value="U3 small nucleolar RNA-associated protein 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010678">
        <property type="entry name" value="UTP25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053939">
        <property type="entry name" value="UTP25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053940">
        <property type="entry name" value="UTP25_NTPase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933">
        <property type="entry name" value="ORF PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06862">
        <property type="entry name" value="Utp25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22916">
        <property type="entry name" value="UTP25_NTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <feature type="chain" id="PRO_0000408122" description="U3 small nucleolar RNA-associated protein 25">
        <location>
            <begin position="1"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="722" mass="82132" checksum="F486F4C52C5AEB36" modified="2012-01-25" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>A4RGK6</accession>
    <name>A4RGK6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ent-kaurene oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_00024</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719122.1">
        <property type="nucleotide sequence ID" value="XM_003719074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RGK6"/>
    <dbReference type="SMR" id="A4RGK6"/>
    <dbReference type="GeneID" id="2675153"/>
    <dbReference type="KEGG" id="mgr:MGG_00024"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00024"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_3_1"/>
    <dbReference type="InParanoid" id="A4RGK6"/>
    <dbReference type="OMA" id="QNVARKP"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA49538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="541" mass="60366" checksum="E9284A0F7884560D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKK3</accession>
    <name>G4MKK3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_04463</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710998.1">
        <property type="nucleotide sequence ID" value="XM_003710950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKK3"/>
    <dbReference type="SMR" id="G4MKK3"/>
    <dbReference type="FunCoup" id="G4MKK3">
        <property type="interactions" value="815"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKK3"/>
    <dbReference type="GeneID" id="2678161"/>
    <dbReference type="KEGG" id="mgr:MGG_04463"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04463"/>
    <dbReference type="eggNOG" id="KOG2345">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_109_1_1"/>
    <dbReference type="InParanoid" id="G4MKK3"/>
    <dbReference type="OMA" id="AMHQYKV"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032889">
        <property type="term" value="P:regulation of vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000550">
        <property type="entry name" value="Serine/threonine kinase 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000374">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052239">
        <property type="entry name" value="Ser/Thr-specific_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998:SF2">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="32"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="163"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="207"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA58386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="442" mass="47356" checksum="D7FBE42756C9C161" modified="2011-12-14" version="1">MAQILQDLIYSLGNCLNCFPGSPTLKINGRSFKILRLLGEGGFSYVYLVQDTATSELLALKKIRCPFGAESVTQAMREVEAYKLFDHSDGIIHSVDYSISTDRGGDESSKTVYVLLPYYRRGNLQDMINANLVNHTRFPERRLMELFLGVCRALRDMHVYNGGGAGGGNEPRQVERMEVPSTNTPAPAAGGGKKKGKGKAKAKGKGKATEENGRARTRETGADEDDESAQQLPLMVGEDDRGASSHGVQGGATKSYAHRDIKPGNIMISDDGQSPILMDLGSIAESPLAITSRSLAIATQDTAAEHSTMPYRAPELFDVKTGTVIDTKVDIWSMGCTLYACLVGKSPFEARSDETGGSLSICVLSGDWRFPDEGAKGKGKASAGSNAAGGAGAGGDDDTSISEPIREVVRRCLAVEPSERPDVDELITLVERVIDELPDDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKW7</accession>
    <name>G4MKW7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710214.1">
        <property type="nucleotide sequence ID" value="XM_003710166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKW7"/>
    <dbReference type="SMR" id="G4MKW7"/>
    <dbReference type="GeneID" id="2676161"/>
    <dbReference type="KEGG" id="mgr:MGG_05369"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05369"/>
    <dbReference type="eggNOG" id="ENOG502SSPQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_533271_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKW7"/>
    <dbReference type="OMA" id="EMHIANA"/>
    <dbReference type="OrthoDB" id="5137723at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="571" mass="65040" checksum="7A6EFB15FB40EC47" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKW9</accession>
    <name>G4MKW9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription initiation factor IIB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General transcription factor TFIIB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_05370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFIIB family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710216.1">
        <property type="nucleotide sequence ID" value="XM_003710168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKW9"/>
    <dbReference type="SMR" id="G4MKW9"/>
    <dbReference type="FunCoup" id="G4MKW9">
        <property type="interactions" value="815"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKW9"/>
    <dbReference type="GeneID" id="2676162"/>
    <dbReference type="KEGG" id="mgr:MGG_05370"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05370"/>
    <dbReference type="eggNOG" id="KOG1597">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043736_1_0_1"/>
    <dbReference type="InParanoid" id="G4MKW9"/>
    <dbReference type="OMA" id="DHDQRMK"/>
    <dbReference type="OrthoDB" id="25790at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd20551">
        <property type="entry name" value="CYCLIN_TFIIB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="8">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA57604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="371" mass="39842" checksum="B4B5193EB58C5133" modified="2011-12-14" version="1">MASMADIGLEADPYQADLNNTMQCNDCGVPTLLQEEVSSGDIVCTECGLVVGARIVDMGSEWRTFANDEAGDDPSRVGDAGNEIYGPSALETKVDMRRDQGASYKIMKSLNAANKKIQNEKGQAAINAGMAKIKDLVDKIHGGGNVIKQAQSLFREVEEAKALKGKSADAAVAGCIFIACRMEKVPRTFREIHALTNVSKKEIGRTYKALEEYVKKVNYENRGGAAAVDHKMPTADDDDDDMATKGTTAESLCTRYCSILGFRVSHLAERVAMHLARKSSSVADLAGRSPLSVAAACIYMMSHLIGEPRTSKDIAVVAGVSDGTIKTAYKFLLAAKDELCRDGEFDPATKQRREGLNLPASCPGHKALPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML31</accession>
    <name>G4ML31_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTP-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_08640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711070.1">
        <property type="nucleotide sequence ID" value="XM_003711022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML31"/>
    <dbReference type="SMR" id="G4ML31"/>
    <dbReference type="FunCoup" id="G4ML31">
        <property type="interactions" value="1056"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ML31"/>
    <dbReference type="GeneID" id="2678872"/>
    <dbReference type="KEGG" id="mgr:MGG_08640"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08640"/>
    <dbReference type="eggNOG" id="KOG1486">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044997_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML31"/>
    <dbReference type="OMA" id="DVCDQVH"/>
    <dbReference type="OrthoDB" id="603at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903833">
        <property type="term" value="P:positive regulation of cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000003">
        <property type="entry name" value="Developmentally-regulated GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000740">
        <property type="entry name" value="Putative GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1070">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="65"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="292"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA58458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="371" mass="41136" checksum="BB5E076FAAD559A9" modified="2011-12-14" version="1">MVNITEKIKEIEDEMRKTQKNKATEYHLGLLKGKLARLRAQLLEPGPGSGGGPGAGFDVSKSGDARISLVGFPSVGKSTFLSKVTKTRSEVAAYSFTTLTAIPGVLEYGGAEIQLLDLPGIIEGAAEGKGRGRQVISAAKTSDMILMVLDATKKAEQRALLEAELEAVGIRLNREPPNIYLKPKKAGGMKINFASPPKRLDEKMVYNILRDYKMLNAEVLIRDDNATVDDLIDVIMKDHRKYIKCLYVYNKIDSVSLDFLDKLAREPHTVVMSCELDLGIQDVIDRCWKELSLVRIYTKRKGIDPDFSEALIVRSNSTIEDVCDRIHRTLKETFKYALVWGASARHVPQRVGLGHPVADEDVVYIVSGYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML93</accession>
    <name>G4ML93_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_11869</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CENP-W/WIP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709441.1">
        <property type="nucleotide sequence ID" value="XM_003709393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML93"/>
    <dbReference type="SMR" id="G4ML93"/>
    <dbReference type="STRING" id="242507.G4ML93"/>
    <dbReference type="GeneID" id="5049660"/>
    <dbReference type="KEGG" id="mgr:MGG_11869"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11869"/>
    <dbReference type="eggNOG" id="ENOG502SEGJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159428_1_1_1"/>
    <dbReference type="InParanoid" id="G4ML93"/>
    <dbReference type="OMA" id="YILFMQE"/>
    <dbReference type="OrthoDB" id="2543597at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13732">
        <property type="entry name" value="HFD_CENP-W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000075">
        <property type="entry name" value="WGS project CABT00000000 data, contig 2.56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052484">
        <property type="entry name" value="CENP-W/WIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34832:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="9">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA56829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="78" mass="8655" checksum="475692B63491DEC7" modified="2011-12-14" version="1">MAPGRKLYPRATVKKIIKAESDCNVSKDADVTIFVDYIRFLQTVVKEAAIESKKAGEKGITPRSVKKVTPDSLSKFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLS8</accession>
    <name>G4MLS8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710318.1">
        <property type="nucleotide sequence ID" value="XM_003710270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLS8"/>
    <dbReference type="GeneID" id="12986281"/>
    <dbReference type="KEGG" id="mgr:MGG_16365"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16365"/>
    <dbReference type="HOGENOM" id="CLU_2015719_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLS8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="123" mass="13405" checksum="954A8D628C6E5320" modified="2011-12-14" version="1">MFFQVPLRDKAVAGAMLKGHSFPGILCPGGLKLAAGRRWAFRPRIAVRTRRSTRDGGASFQRALTNRSSPATCYAGVPKGNALQKGVGYLVLGCGPGCLPIQRSSRRIKGPSWMRGKWRYSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLT5</accession>
    <name>G4MLT5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05459</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710325.1">
        <property type="nucleotide sequence ID" value="XM_003710277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLT5"/>
    <dbReference type="STRING" id="242507.G4MLT5"/>
    <dbReference type="GeneID" id="2675887"/>
    <dbReference type="KEGG" id="mgr:MGG_05459"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05459"/>
    <dbReference type="eggNOG" id="ENOG502RAQ3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_319122_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLT5"/>
    <dbReference type="OMA" id="PRNTEMH"/>
    <dbReference type="OrthoDB" id="5362630at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="491"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="443"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="911" mass="103021" checksum="3F9117E8FB82FCE1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM33</accession>
    <name>G4MM33_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709530.1">
        <property type="nucleotide sequence ID" value="XM_003709482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM33"/>
    <dbReference type="GeneID" id="5051440"/>
    <dbReference type="KEGG" id="mgr:MGG_14570"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14570"/>
    <dbReference type="eggNOG" id="ENOG502SSZ7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_885879_0_0_1"/>
    <dbReference type="InParanoid" id="G4MM33"/>
    <dbReference type="OrthoDB" id="4226417at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="34071" checksum="F1986F34FD2E1A8B" modified="2011-12-14" version="1">MSDEIIDLYTQKRQTIFPGSSGSFGGQLLPELLPAAEIQRKFPRELPVTRTKNGVTKNRKIPALGIHSDLFKRWAEAIDEKPPNSPVSKNGTAGKPSKHDSTASLLPTGQPGETLSQSYGDKYRDVFELQYGCGNYITVAQKINPIRDEPTLVALVKGLSYLEAEGLEHGQLSCSEILVDTSGQVKIWSYENCQPVVQDCADMRSLSKITMELMQGYCKENGRVGVDDLVRWPADSRAVDFLSVTADTSDLGLLSNGFGNCTVATLERNPNQAFSVANVIRNFAAESAGQKRNPSDVSSQCGPNLGSAGGQIWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM40</accession>
    <name>G4MM40_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_16181</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709537.1">
        <property type="nucleotide sequence ID" value="XM_003709489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM40"/>
    <dbReference type="GeneID" id="12984547"/>
    <dbReference type="KEGG" id="mgr:MGG_16181"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16181"/>
    <dbReference type="eggNOG" id="KOG2029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_266185_0_0_1"/>
    <dbReference type="InParanoid" id="G4MM40"/>
    <dbReference type="OMA" id="MEAMWIN"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="561"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="971"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="561"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="978"/>
            <end position="989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA56925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1246" mass="137201" checksum="82547BA1FD37E61C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMI4</accession>
    <name>G4MMI4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DC-UbP/UBTD2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06853</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709574.1">
        <property type="nucleotide sequence ID" value="XM_003709526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMI4"/>
    <dbReference type="SMR" id="G4MMI4"/>
    <dbReference type="STRING" id="242507.G4MMI4"/>
    <dbReference type="GeneID" id="2685026"/>
    <dbReference type="KEGG" id="mgr:MGG_06853"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06853"/>
    <dbReference type="eggNOG" id="KOG0013">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054816_2_0_1"/>
    <dbReference type="InParanoid" id="G4MMI4"/>
    <dbReference type="OMA" id="GCMGRYL"/>
    <dbReference type="OrthoDB" id="1640476at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.225.20">
        <property type="entry name" value="Ub domain-containing protein, DC-UbP/UBTD2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032752">
        <property type="entry name" value="DC-UbP/UBTD2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038169">
        <property type="entry name" value="DC-UbP/UBTD2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039869">
        <property type="entry name" value="UBTD1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13609">
        <property type="entry name" value="UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16455">
        <property type="entry name" value="UBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DC-UbP/UBTD2 N-terminal" evidence="2">
        <location>
            <begin position="71"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="327" mass="36076" checksum="BE64397703577B8D" modified="2011-12-14" version="1">MGCCGSRPTGPNSPYPGDAASASARAINTVATRPAASSPLSGDAEAAASPTSTRAPQQRHRHRQPLDQHINKPLRRHRWASRSRVWTREDLAAERKDFFDTRVTGRVEVWQAIKTALEVLWESDPNHPPGTTAPTQEQQEEALLTAQSIMMAADITLPTGNLAQGVYDQLGNYYPLPEHVVCNPVNVINVSDLPPSEDGDEIDDDDVDIGSIGDTKQHYVASSAEDDETDKAAQRRKEKGKEVEVEEETITVRCRLSENARDVMVTVPKKSPVRVLARRIVEEAKLPDDTSVRIAYLGKILRDTTPLTLQGWQEGHVLNAMCFSKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMK5</accession>
    <name>G4MMK5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709595.1">
        <property type="nucleotide sequence ID" value="XM_003709547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMK5"/>
    <dbReference type="GeneID" id="12985216"/>
    <dbReference type="KEGG" id="mgr:MGG_16197"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16197"/>
    <dbReference type="HOGENOM" id="CLU_1750055_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMK5"/>
    <dbReference type="OrthoDB" id="10611785at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="149" mass="16540" checksum="0E24E4120BF686F9" modified="2011-12-14" version="1">MTSDFASHSACIRKKSDKIRAKAMMQGATANYQTSAYLPGDLERDGPPLSPVVDRPNSQNLGTNLGKTGNAKRVTQPGKCQAPLFVPFQQQQPEEKGWRRGAVTCSSSPSGSPVVWGFQRAKKKSIEQKMVNRSTWGWLEWNILLNGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN30</accession>
    <name>G4MN30_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CAIB/BAIF family enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710456.1">
        <property type="nucleotide sequence ID" value="XM_003710408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN30"/>
    <dbReference type="SMR" id="G4MN30"/>
    <dbReference type="STRING" id="242507.G4MN30"/>
    <dbReference type="GeneID" id="2676060"/>
    <dbReference type="KEGG" id="mgr:MGG_05580"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05580"/>
    <dbReference type="eggNOG" id="KOG3957">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021588_1_1_1"/>
    <dbReference type="InParanoid" id="G4MN30"/>
    <dbReference type="OMA" id="GEFFHIH"/>
    <dbReference type="OrthoDB" id="2308815at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052985">
        <property type="entry name" value="CoA-trans_III_biosynth/detox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48229:SF1">
        <property type="entry name" value="ALPHA METHYLACYL-COA RACEMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48229">
        <property type="entry name" value="CAIB/BAIF FAMILY ENZYME (AFU_ORTHOLOGUE AFUA_1G05360)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="531"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="631"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="537"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="657" mass="71655" checksum="C41101B1A15EC130" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN59</accession>
    <name>G4MN59_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Serine/threonine-protein kinase TOR</fullName>
            <ecNumber evidence="16">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MGG_15156</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associates with DNA double-strand breaks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Vacuole membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="16"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710485.1">
        <property type="nucleotide sequence ID" value="XM_003710437.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MN59"/>
    <dbReference type="FunCoup" id="G4MN59">
        <property type="interactions" value="1058"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MN59"/>
    <dbReference type="GeneID" id="12986351"/>
    <dbReference type="KEGG" id="mgr:MGG_15156"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15156"/>
    <dbReference type="eggNOG" id="KOG0891">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000178_7_1_1"/>
    <dbReference type="InParanoid" id="G4MN59"/>
    <dbReference type="OMA" id="MRQHSAK"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016242">
        <property type="term" value="P:negative regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905356">
        <property type="term" value="P:regulation of snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05169">
        <property type="entry name" value="PIKKc_TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000020">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.150:FF:000001">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000371">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000006">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
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    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
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    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
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    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
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    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
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    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
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    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
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    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
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    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026683">
        <property type="entry name" value="TOR_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9 16 21" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="FAT" evidence="19">
        <location>
            <begin position="1247"/>
            <end position="1862"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="18">
        <location>
            <begin position="2037"/>
            <end position="2353"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="20">
        <location>
            <begin position="2428"/>
            <end position="2460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1557"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2357"/>
            <end position="2392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="2382"/>
            <end position="2392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU364109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EHA57873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="2460" mass="277516" checksum="303B8D1C4F467B6A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNI0</accession>
    <name>G4MNI0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CENP-C homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_06960</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CENP-C/MIF2 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA57094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709706.1">
        <property type="nucleotide sequence ID" value="XM_003709658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNI0"/>
    <dbReference type="SMR" id="G4MNI0"/>
    <dbReference type="STRING" id="242507.G4MNI0"/>
    <dbReference type="GeneID" id="2685133"/>
    <dbReference type="KEGG" id="mgr:MGG_06960"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06960"/>
    <dbReference type="eggNOG" id="ENOG502S47H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027966_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNI0"/>
    <dbReference type="OMA" id="CHGRVQV"/>
    <dbReference type="OrthoDB" id="1939643at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019237">
        <property type="term" value="F:centromeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051455">
        <property type="term" value="P:spindle attachment to meiosis I kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06993">
        <property type="entry name" value="cupin_CENP-C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000033">
        <property type="entry name" value="Centromere protein C 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028386">
        <property type="entry name" value="CENP-C/Mif2/cnp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025974">
        <property type="entry name" value="Mif2/CENP-C_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028929">
        <property type="entry name" value="Mif2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684:SF11">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11699">
        <property type="entry name" value="CENP-C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15624">
        <property type="entry name" value="Mif2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mif2 N-terminal" evidence="9">
        <location>
            <begin position="19"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Mif2/CENP-C cupin" evidence="8">
        <location>
            <begin position="573"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="477"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="176"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="365"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="491"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00057947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00075033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF15624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA57094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="676" mass="73415" checksum="3A0B2F503677B7AF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNQ8</accession>
    <name>G4MNQ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708886.1">
        <property type="nucleotide sequence ID" value="XM_003708838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNQ8"/>
    <dbReference type="GeneID" id="2681207"/>
    <dbReference type="KEGG" id="mgr:MGG_02116"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02116"/>
    <dbReference type="eggNOG" id="ENOG502RNDH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="InParanoid" id="G4MNQ8"/>
    <dbReference type="OrthoDB" id="5242160at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="453" mass="50211" checksum="92EA1835B2A9FBD3" modified="2011-12-14" version="1">MSSHSVQQNAMARDDNPAHPGPMLDLKGEASSVALLPFGPRVQVNLVRMLNSVVEDVGSRADPVGFAWDDSHSNQAAKVVRRMLRNGDNEKRFITIKLLSYIQSHKTVQAQNEEENGLHTKKHQKEKARRLQGELLAFFLSLTAEIKSLRGSPSQPAFNFSDLENEVNRVRHLVRKVSAPFRLTHRTQERPTGDLYHVNSLAISLNKPFLLSLALVSDPDDSPSGQGPGKTASPHIFRLTWPKVESKPLTTSSQSTPGSISAAVQPVSTLHPTDAVYIKQEPGHDTDRSGQAVIVNSSPGHGNERMPNANQQLTRMVGDTMMLPRIVVEIGHLAIVHTTTTEHRHEVPITATGLGLFVDLEDVNKGLWLLRTDNYIGVRLDDQPSLESGLIAFFKKRKLHKNCGNAKLSRSISDWFESFTGEQQVHVLQHTGSIKADLRRLVPKFETFAVSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNY1</accession>
    <name>G4MNY1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein uS5m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_06995</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA57138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709750.1">
        <property type="nucleotide sequence ID" value="XM_003709702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNY1"/>
    <dbReference type="SMR" id="G4MNY1"/>
    <dbReference type="STRING" id="242507.G4MNY1"/>
    <dbReference type="GeneID" id="2685168"/>
    <dbReference type="KEGG" id="mgr:MGG_06995"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06995"/>
    <dbReference type="eggNOG" id="KOG2646">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037994_1_0_1"/>
    <dbReference type="InParanoid" id="G4MNY1"/>
    <dbReference type="OMA" id="IYEMCRA"/>
    <dbReference type="OrthoDB" id="309483at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000022">
        <property type="entry name" value="28S ribosomal protein S5, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000041">
        <property type="entry name" value="37S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="10">
        <location>
            <begin position="280"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA57138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="444" mass="49248" checksum="696AC04BD0715CB7" modified="2011-12-14" version="1">MSAARPAARSLLSRRCLGGAPNAAVPSSVLAATQVQQPPTCRRQFHASAPVEVRRRPRFSNVHAKAMGLVTEEDVSKVTNETFPELTKEELAAMEKIYTPEQLEALKAGEKAVDPRDLTVQGRVRIDPYRLGYLSDLSKIDPVVDKRVKKEAPPNTRARFMTGPEFVLDFYSWMKSFLPKNINLEKDLKNMSEDELNELLDKYTPSHTDLFNFMVNRSSMTDGGQLSNTAVAPALMSKVPGVAGLYKRQVDPADEGLDDEGKYQHAKKQTGLSVQDILGLRHKILVQRFVTNQTRLGKVQSWHIMTIVGNGNGRIGLGEAKSVDGQIAMHKARLMAIKNMVPIRRYEDRTIYGKVKVKIAGTVVEMAARPPGFGLRISHRLFEICRLAGIKDLSASIPRSRNPMNTVKAAMKALQSQPDPEAIAIGRGKKLVDVRKVYYGGHVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQA8</accession>
    <name>G4MQA8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709913.1">
        <property type="nucleotide sequence ID" value="XM_003709865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQA8"/>
    <dbReference type="GeneID" id="12985290"/>
    <dbReference type="KEGG" id="mgr:MGG_16267"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16267"/>
    <dbReference type="HOGENOM" id="CLU_2831655_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQA8"/>
    <dbReference type="OrthoDB" id="10528985at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="66" mass="7023" checksum="92A9A79926F5F88F" modified="2011-12-14" version="1">MPTGSPSKSDPGVAPDFVTPTYRNPSAHPSYSIPTCYPRYKIITCHALGLVHSKYGIGSLGGTPFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQU5</accession>
    <name>G4MQU5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_13766</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710788.1">
        <property type="nucleotide sequence ID" value="XM_003710740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQU5"/>
    <dbReference type="SMR" id="G4MQU5"/>
    <dbReference type="GeneID" id="2677957"/>
    <dbReference type="KEGG" id="mgr:MGG_13766"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13766"/>
    <dbReference type="eggNOG" id="ENOG502RXEE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_0_2_1"/>
    <dbReference type="InParanoid" id="G4MQU5"/>
    <dbReference type="OMA" id="HTVLSFM"/>
    <dbReference type="OrthoDB" id="10000533at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF4">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA58176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="320" mass="35517" checksum="4CD6A28945141FEF" modified="2011-12-14" version="1">MVKIAIAGGSSGVGQEIVEDLVAAKKHEILLLTRKFPDGTEPAQDGVTWVHADYGDVSQLASLLQGVHTVLSFVIPSINTTGKSDEQKNLVDAAIRAGVKRFAPSEWVGWNLDPAPWYQYKKPMREYLAEVNKDAKVLEYCLFQPGFFTNYLVHPRRTTKHLQTLELNLDFPNRRAIVAEGSENSHITLTTVRDLAAVVALAVEYPGEWPVVGGIRGEHMTVGELLALGERIYGRSPLSNLGLAWNDLEAGILKSSWRPEPDHPAVPKNMTEAEKDFVPARFAMNIKAEVLASSDEWNRLLPDYKFTKVEEFITGIVGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR30</accession>
    <name>G4MR30_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_16286</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709974.1">
        <property type="nucleotide sequence ID" value="XM_003709926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR30"/>
    <dbReference type="STRING" id="242507.G4MR30"/>
    <dbReference type="GeneID" id="12985310"/>
    <dbReference type="KEGG" id="mgr:MGG_16286"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16286"/>
    <dbReference type="eggNOG" id="KOG2214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009031_5_0_1"/>
    <dbReference type="InParanoid" id="G4MR30"/>
    <dbReference type="OMA" id="SIVPWPH"/>
    <dbReference type="OrthoDB" id="10049244at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07229">
        <property type="entry name" value="Pat_TGL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF44">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="7">
        <location>
            <begin position="207"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA57362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="575" mass="64246" checksum="BC8EFC9E7612A4FC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRD2</accession>
    <name>G4MRD2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal STAND N-terminal Goodbye domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710869.1">
        <property type="nucleotide sequence ID" value="XM_003710821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRD2"/>
    <dbReference type="GeneID" id="2677858"/>
    <dbReference type="KEGG" id="mgr:MGG_04634"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04634"/>
    <dbReference type="eggNOG" id="ENOG502SHRF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_366827_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRD2"/>
    <dbReference type="OMA" id="KAEDNRF"/>
    <dbReference type="OrthoDB" id="5419927at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40619:SF3">
        <property type="entry name" value="FUNGAL STAND N-TERMINAL GOODBYE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="749" mass="85831" checksum="3F1141F548664599" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSA7</accession>
    <name>G4MSA7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710977.1">
        <property type="nucleotide sequence ID" value="XM_003710929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSA7"/>
    <dbReference type="GeneID" id="12986875"/>
    <dbReference type="KEGG" id="mgr:MGG_15296"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15296"/>
    <dbReference type="HOGENOM" id="CLU_1343496_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSA7"/>
    <dbReference type="OrthoDB" id="4499833at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="204" mass="21915" checksum="38FE4A7BC53161DF" modified="2011-12-14" version="1">MGSKSSKVASRSGDPSDRASSQDNSPHRNNPNRRLANPSRRSYQRPQNDRPFPGPPPRVPGSSSAGSAARPSPAPSVASNALSRVTTASSSGASHVAPLRTRPTDSSYGPRLSFKIWNKPDNCPLTVAPPAPGDYYLHAPLIPGQTEPYKQGQGPGGVRAVYNRNDQTHFDVIQHDTKKPQTASGAHQFTMRPYVPAATRPPHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT44</accession>
    <name>G4MT44_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lon protease homolog 2, peroxisomal</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_07123</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9 12">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715316.1">
        <property type="nucleotide sequence ID" value="XM_003715268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT44"/>
    <dbReference type="SMR" id="G4MT44"/>
    <dbReference type="STRING" id="242507.G4MT44"/>
    <dbReference type="GeneID" id="2683245"/>
    <dbReference type="KEGG" id="mgr:MGG_07123"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07123"/>
    <dbReference type="eggNOG" id="KOG2004">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004109_4_0_1"/>
    <dbReference type="InParanoid" id="G4MT44"/>
    <dbReference type="OMA" id="MPMNQEY"/>
    <dbReference type="OrthoDB" id="2411602at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5270:FF:000002">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000091">
        <property type="entry name" value="Lon protease homolog 2, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000039">
        <property type="entry name" value="Lon protease homolog 2, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03121">
        <property type="entry name" value="lonp2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027501">
        <property type="entry name" value="Lonp2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="ATP DEPENDENT LON PROTEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="15">
        <location>
            <begin position="9"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="14">
        <location>
            <begin position="726"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="296"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Microbody targeting signal" evidence="8">
        <location>
            <begin position="927"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 10 12">
        <location>
            <position position="819"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 10 12">
        <location>
            <position position="862"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <begin position="483"/>
            <end position="490"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA55509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="929" mass="101794" checksum="4D85C8AB0FE9533A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT92</accession>
    <name>G4MT92_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713645.1">
        <property type="nucleotide sequence ID" value="XM_003713597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT92"/>
    <dbReference type="GeneID" id="12987141"/>
    <dbReference type="KEGG" id="mgr:MGG_15550"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15550"/>
    <dbReference type="HOGENOM" id="CLU_2400102_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT92"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="93" mass="10508" checksum="35206C7F0DE80F1A" modified="2011-12-14" version="1">MQIWYVPAIVLPSQDDVVLTCKLADKATLRGTYRYSDGPERQRPAHLVVGSFKSSNQDTRSADVLPGRLGHHVRTSRAAFLHLIAARIYRIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTA0</accession>
    <name>G4MTA0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Alpha-galactosidase</fullName>
            <ecNumber evidence="5 12">3.2.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Melibiase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_11374</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="5 12"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713653.1">
        <property type="nucleotide sequence ID" value="XM_003713605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTA0"/>
    <dbReference type="SMR" id="G4MTA0"/>
    <dbReference type="STRING" id="242507.G4MTA0"/>
    <dbReference type="GeneID" id="5051330"/>
    <dbReference type="KEGG" id="mgr:MGG_11374"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11374"/>
    <dbReference type="eggNOG" id="KOG2366">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013093_1_0_1"/>
    <dbReference type="InParanoid" id="G4MTA0"/>
    <dbReference type="OMA" id="VHTWGMS"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005995">
        <property type="term" value="P:melibiose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000202">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006215">
        <property type="entry name" value="Glyco_hydro_melibiase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF75">
        <property type="entry name" value="ALPHA-GALACTOSIDASE MEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00748">
        <property type="entry name" value="MELIBIASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465581" description="Alpha-galactosidase" evidence="14">
        <location>
            <begin position="26"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="15">
        <location>
            <begin position="351"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="494"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA53846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="512" mass="55931" checksum="7A9B03FEE0B521C5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTE1</accession>
    <name>G4MTE1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714499.1">
        <property type="nucleotide sequence ID" value="XM_003714451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTE1"/>
    <dbReference type="SMR" id="G4MTE1"/>
    <dbReference type="STRING" id="242507.G4MTE1"/>
    <dbReference type="GeneID" id="2679739"/>
    <dbReference type="KEGG" id="mgr:MGG_01525"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01525"/>
    <dbReference type="eggNOG" id="ENOG502S6YK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148782_1_1_1"/>
    <dbReference type="InParanoid" id="G4MTE1"/>
    <dbReference type="OMA" id="MLWAKQY"/>
    <dbReference type="OrthoDB" id="2100988at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="92" mass="10683" checksum="4844B1A16665EC3A" modified="2011-12-14" version="1">MGGGPRVKYPKHVWSPAGGWYTNPPNWKANTAISLLAIIGVTAVVWKISAEKEWRPRMPEKDRYYPSRYWSKQIIEHERAEREKEKAAQESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTF5</accession>
    <name>G4MTF5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714513.1">
        <property type="nucleotide sequence ID" value="XM_003714465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTF5"/>
    <dbReference type="GeneID" id="5051159"/>
    <dbReference type="KEGG" id="mgr:MGG_11188"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11188"/>
    <dbReference type="eggNOG" id="ENOG502S984">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013726_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTF5"/>
    <dbReference type="OMA" id="TELSCPM"/>
    <dbReference type="OrthoDB" id="5371510at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="788"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="822" mass="91470" checksum="CBC27AF6549FBDFF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTN1</accession>
    <name>G4MTN1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_07190</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 14"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715396.1">
        <property type="nucleotide sequence ID" value="XM_003715348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTN1"/>
    <dbReference type="SMR" id="G4MTN1"/>
    <dbReference type="FunCoup" id="G4MTN1">
        <property type="interactions" value="906"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTN1"/>
    <dbReference type="GeneID" id="2683173"/>
    <dbReference type="KEGG" id="mgr:MGG_07190"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07190"/>
    <dbReference type="eggNOG" id="KOG3359">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008438_5_0_1"/>
    <dbReference type="InParanoid" id="G4MTN1"/>
    <dbReference type="OMA" id="MCGWDDN"/>
    <dbReference type="OrthoDB" id="292747at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="PHI-base" id="PHI:6348"/>
    <dbReference type="PHI-base" id="PHI:8233"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23284">
        <property type="entry name" value="beta-trefoil_MIR_PMT2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000012">
        <property type="entry name" value="Protein O-mannosyl-transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF46">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="283"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="603"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="645"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="671"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="701"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="337"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="403"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="467"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA55589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="743" mass="85319" checksum="7B5C3706A2163CCB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU29</accession>
    <name>G4MU29_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Iron transport multicopper oxidase FET3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07220</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715436.1">
        <property type="nucleotide sequence ID" value="XM_003715388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU29"/>
    <dbReference type="SMR" id="G4MU29"/>
    <dbReference type="GeneID" id="2683108"/>
    <dbReference type="KEGG" id="mgr:MGG_07220"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07220"/>
    <dbReference type="eggNOG" id="KOG1263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006504_7_3_1"/>
    <dbReference type="InParanoid" id="G4MU29"/>
    <dbReference type="OMA" id="FHGINQI"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010106">
        <property type="term" value="P:cellular response to iron ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033215">
        <property type="term" value="P:reductive iron assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13877">
        <property type="entry name" value="CuRO_2_Fet3p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000071">
        <property type="entry name" value="Conidial pigment biosynthesis oxidase Abr1/brown 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044130">
        <property type="entry name" value="CuRO_2_Fet3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465329" evidence="6">
        <location>
            <begin position="21"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="30"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="153"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="365"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="542" mass="60152" checksum="D7A8AEB2B0D1C02B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUA4</accession>
    <name>G4MUA4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA topoisomerase</fullName>
            <ecNumber evidence="3 7">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_11342</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 7"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713792.1">
        <property type="nucleotide sequence ID" value="XM_003713744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUA4"/>
    <dbReference type="SMR" id="G4MUA4"/>
    <dbReference type="FunCoup" id="G4MUA4">
        <property type="interactions" value="902"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUA4"/>
    <dbReference type="GeneID" id="5051302"/>
    <dbReference type="KEGG" id="mgr:MGG_11342"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11342"/>
    <dbReference type="eggNOG" id="KOG1956">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002929_1_1_1"/>
    <dbReference type="InParanoid" id="G4MUA4"/>
    <dbReference type="OMA" id="VIHNVYS"/>
    <dbReference type="OrthoDB" id="430051at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031422">
        <property type="term" value="C:RecQ family helicase-topoisomerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.290.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.140:FF:000005">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF21">
        <property type="entry name" value="DNA TOPOISOMERASE 3-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPO_IA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="9">
        <location>
            <begin position="3"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="10">
        <location>
            <begin position="167"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="526"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="557"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="568"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA53985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="669" mass="74757" checksum="083E15798009296F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUL9</accession>
    <name>G4MUL9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome biogenesis protein RLP24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_10160</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713799.1">
        <property type="nucleotide sequence ID" value="XM_003713751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUL9"/>
    <dbReference type="SMR" id="G4MUL9"/>
    <dbReference type="FunCoup" id="G4MUL9">
        <property type="interactions" value="984"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUL9"/>
    <dbReference type="GeneID" id="2681787"/>
    <dbReference type="KEGG" id="mgr:MGG_10160"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10160"/>
    <dbReference type="eggNOG" id="KOG1723">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089419_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUL9"/>
    <dbReference type="OMA" id="NAGKEMT"/>
    <dbReference type="OrthoDB" id="10262490at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000001">
        <property type="entry name" value="probable ribosome biogenesis protein RLP24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF8">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="TRASH" evidence="5">
        <location>
            <begin position="6"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="229" mass="26462" checksum="ECC2DFA8637766A1" modified="2011-12-14" version="1">MRIETCYFCSRPAYPGKGIQFVRNDARVFRFCRSKCHKNFKMKRNPRKLKWTKAFRKAAGKEMTVDSTLQLAARRNVPIRYNRDLFQKTLKAMDRIAEIRARRERVFYKKRMAGKREREVAAARKLVAENEHLLPRLRGSEKRRIAEERGITVEEVEEMSVGEMVEKAKLSKKAGKSKLFGKEVVRQRVRADGGIDTVVERTVGAGEDDDEDDAEWGSDADDVDGMDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUM8</accession>
    <name>G4MUM8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15586</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713808.1">
        <property type="nucleotide sequence ID" value="XM_003713760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUM8"/>
    <dbReference type="GeneID" id="12987236"/>
    <dbReference type="KEGG" id="mgr:MGG_15586"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15586"/>
    <dbReference type="HOGENOM" id="CLU_2868106_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUM8"/>
    <dbReference type="OMA" id="NMMEALM"/>
    <dbReference type="OrthoDB" id="5168384at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="64" mass="7632" checksum="6F8C6E6DEBBE1A46" modified="2011-12-14" version="1">MIMKWVLKIGDSQPGTNRQPQLRGGQFPARQGSVRIGYHCLHNDMRRYKWHRVNMMEALMYSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUV0</accession>
    <name>G4MUV0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_01695</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714687.1">
        <property type="nucleotide sequence ID" value="XM_003714639.1"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUV0"/>
    <dbReference type="GeneID" id="2679169"/>
    <dbReference type="KEGG" id="mgr:MGG_01695"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01695"/>
    <dbReference type="eggNOG" id="ENOG502QVFV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004333_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUV0"/>
    <dbReference type="OMA" id="GDEICRG"/>
    <dbReference type="OrthoDB" id="4066896at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057454">
        <property type="entry name" value="Bud3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF261">
        <property type="entry name" value="BUD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25351">
        <property type="entry name" value="PH_BUD3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="249"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1098"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1288"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1387"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1474"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1298"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1325"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1346"/>
            <end position="1359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1517" mass="169154" checksum="9924429F524D10AE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVG1</accession>
    <name>G4MVG1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutathionylspermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_07354</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715594.1">
        <property type="nucleotide sequence ID" value="XM_003715546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVG1"/>
    <dbReference type="SMR" id="G4MVG1"/>
    <dbReference type="STRING" id="242507.G4MVG1"/>
    <dbReference type="GeneID" id="2683073"/>
    <dbReference type="KEGG" id="mgr:MGG_07354"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07354"/>
    <dbReference type="eggNOG" id="ENOG502QUZK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059175_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVG1"/>
    <dbReference type="OMA" id="DEIYWDE"/>
    <dbReference type="OrthoDB" id="64566at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005494">
        <property type="entry name" value="GSPS_pre-ATP-grasp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03738">
        <property type="entry name" value="GSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathionylspermidine synthase pre-ATP-grasp-like" evidence="6">
        <location>
            <begin position="16"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA55787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="447" mass="50538" checksum="1566A09ECCDFAAB1" modified="2011-12-14" version="1">MRRVRTEPRPNFVRLLHSQGLVFNRDPIPAGQHEHYWPDDRYYAFTGEEIKLLQDAAADVFAMLCEATDYLTERPELIASRLAIPEFCLKQIVESWKRTPAFGSVYSRFDICFGGLDHADPQLRVPRFYEINADTPTTLIESASIQFSWLQQTGHGPDQYNDVEEKLIAAWQRNMAEIERKLGHRPKVHFASTRTRDGEDEINTEYLAATCQTAGYETKNTWLDQISLGRDGRLYDQDGEHIDVVYKLYPWELIIKEKFAQACFSDMENIGRRDASGSKAMFAILWELFRDDPRGRWLLPTYLEAERPADMVRYARKPIFARKGAGVTLQDGDETIIRTGACGFGDEGYVVQELAVLPAFGGDEDGKARRPSYPVIGLWMIDGAPAGMGIREDVGQVTGDSSSFIPNVIEDAPEVNYERQPVPTLGEIEAVLSLDTYYESGVLKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVP7</accession>
    <name>G4MVP7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plasma membrane channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_01769</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714771.1">
        <property type="nucleotide sequence ID" value="XM_003714723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVP7"/>
    <dbReference type="GeneID" id="2679497"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01769"/>
    <dbReference type="eggNOG" id="KOG2513">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4MVP7"/>
    <dbReference type="OrthoDB" id="296386at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="596"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="646"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="689"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="7">
        <location>
            <begin position="96"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="6">
        <location>
            <begin position="257"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="825" mass="93243" checksum="B8343789110AA0E3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWF4</accession>
    <name>G4MWF4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor BYE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_12463</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Negative regulator of transcription elongation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BYE1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715721.1">
        <property type="nucleotide sequence ID" value="XM_003715673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWF4"/>
    <dbReference type="SMR" id="G4MWF4"/>
    <dbReference type="STRING" id="242507.G4MWF4"/>
    <dbReference type="GeneID" id="5051058"/>
    <dbReference type="KEGG" id="mgr:MGG_12463"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12463"/>
    <dbReference type="eggNOG" id="KOG1634">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009292_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWF4"/>
    <dbReference type="OMA" id="AWISCET"/>
    <dbReference type="OrthoDB" id="79252at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001139">
        <property type="term" value="F:RNA polymerase II complex recruiting activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031440">
        <property type="term" value="P:regulation of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21538">
        <property type="entry name" value="SPOC_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
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        <source>
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        <source>
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    <sequence length="1118" mass="119489" checksum="8AB9AF687463F491" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY34</accession>
    <name>G4MY34_PYRO7</name>
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        <submittedName>
            <fullName evidence="10">AGC/RSK/P70 protein kinase</fullName>
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        <name evidence="10" type="ORF">MGG_01260</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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            <end position="486"/>
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            <begin position="104"/>
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        <source>
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        <source>
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        <source>
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        <source>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY97</accession>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the RNR ribonuclease family.</text>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
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                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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        <property type="entry name" value="ZINC FINGER PROTEIN"/>
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        <property type="entry name" value="ZnF_C2H2"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="807"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="816"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="855" mass="94507" checksum="4DD0AC4E42C38188" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYJ4</accession>
    <name>G4MYJ4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-keto-steroid reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_01303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714226.1">
        <property type="nucleotide sequence ID" value="XM_003714178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYJ4"/>
    <dbReference type="FunCoup" id="G4MYJ4">
        <property type="interactions" value="140"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYJ4"/>
    <dbReference type="GeneID" id="2679584"/>
    <dbReference type="KEGG" id="mgr:MGG_01303"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01303"/>
    <dbReference type="eggNOG" id="KOG1478">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029944_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYJ4"/>
    <dbReference type="OMA" id="WTGINWP"/>
    <dbReference type="OrthoDB" id="9989144at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000253">
        <property type="term" value="F:3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051593">
        <property type="entry name" value="Ergosterol_Biosynth_ERG27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43647:SF1">
        <property type="entry name" value="3-KETO-STEROID REDUCTASE ERG27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43647">
        <property type="entry name" value="DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="498" mass="55006" checksum="E8F84DEC566FE846" modified="2011-12-14" version="1">MAVPNAVPWGDVPRRDQLFVLVTGTNSGVGTGIAERLIDEFLVKRSLTSHLILIVTTRSKAKSQQIIDILRKHVRKAAEAKKLRGRAGPSYDPESTVARIHLVGILVDLCNLHSVYAAANLLKDGGSPAAGSNCPSSVRVPRLDSIILNAGYGNWTSLNWWGLFVQLVTKGIPISFTWPAFKNAAKGTLVDPLTGRVLTKEQAIAEGRTSAELLGETFTANLFGHYMFAHALLPLLRRSPEQLAEEALSPARIIWQGSVTVGPDEYSTSDPQGLRHHDAYDYVKRLNDILVFSSTLPKPKPLATAYLLGEDNNDGKNNSDKLVAPRMYLTHPGITNTAIFALPFTLSVIWGWVMYLTRWLGSVWHVGSPYNSAFSPVWIALEEQSRLDDMEAHRSKWGSACSRWRGTLGAKKTEIHGWGWDGRLASHPRGRPAESETGFLSRDLGRRQDAVELTQDALAEFEEQGAECWREMERLRAEWEERLGVRTAASGDKIALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYJ6</accession>
    <name>G4MYJ6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b-c1 complex subunit 6, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Complex III subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_01305</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714228.1">
        <property type="nucleotide sequence ID" value="XM_003714180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYJ6"/>
    <dbReference type="SMR" id="G4MYJ6"/>
    <dbReference type="STRING" id="242507.G4MYJ6"/>
    <dbReference type="GeneID" id="2679586"/>
    <dbReference type="KEGG" id="mgr:MGG_01305"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01305"/>
    <dbReference type="eggNOG" id="KOG4763">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115913_0_2_1"/>
    <dbReference type="InParanoid" id="G4MYJ6"/>
    <dbReference type="OMA" id="NEDCVEE"/>
    <dbReference type="OrthoDB" id="405848at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.20:FF:000003">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
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    <name>G4MZI7_PYRO7</name>
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        <recommendedName>
            <fullName evidence="3">Apple domain-containing protein</fullName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Pezizomycotina</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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        <property type="entry name" value="TM_EGFR-like"/>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003712033.1"/>
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    <dbReference type="STRING" id="242507.G4N0E0"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_06195"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <begin position="376"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <end position="483"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52274.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="550" mass="62296" checksum="0F38DE81BD52AE66" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0F2</accession>
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        <recommendedName>
            <fullName evidence="1">RNA-dependent RNA polymerase</fullName>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RdRP family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="1"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712093.1">
        <property type="nucleotide sequence ID" value="XM_003712045.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N0F2"/>
    <dbReference type="STRING" id="242507.G4N0F2"/>
    <dbReference type="GeneID" id="2684355"/>
    <dbReference type="KEGG" id="mgr:MGG_06205"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06205"/>
    <dbReference type="eggNOG" id="KOG0988">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001366_2_0_1"/>
    <dbReference type="InParanoid" id="G4N0F2"/>
    <dbReference type="OMA" id="GIMDETN"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057503">
        <property type="entry name" value="PH_RdRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF17">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25358">
        <property type="entry name" value="PH_fung_RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 5" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RdRP-like PH" evidence="4">
        <location>
            <begin position="153"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="RDRP core" evidence="3">
        <location>
            <begin position="459"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA52286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1292" mass="146333" checksum="3B296C19E1F215DA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0F7</accession>
    <name>G4N0F7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inorganic phosphate transporter PHO88</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712098.1">
        <property type="nucleotide sequence ID" value="XM_003712050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0F7"/>
    <dbReference type="FunCoup" id="G4N0F7">
        <property type="interactions" value="234"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N0F7"/>
    <dbReference type="GeneID" id="2684351"/>
    <dbReference type="KEGG" id="mgr:MGG_06209"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06209"/>
    <dbReference type="eggNOG" id="KOG4554">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099163_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0F7"/>
    <dbReference type="OMA" id="NMDYDKG"/>
    <dbReference type="OrthoDB" id="18139at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008756">
        <property type="entry name" value="P_tr_PHO88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="192" mass="20745" checksum="28268035E6CD622F" modified="2011-12-14" version="1">MAGLSPQITNMVIILGMVQVAKKIPFEDPNVLNMARAGYILSNVIILAIHLYIMSTINKKKDLTTLKYVEPAPMGSSEEPKLVTTTIHAYDMGQLKTALRSQAMGVGMMAFMHLYMKYTNPLLIQSIIPLKGVFESNLAKIHLFGQPAAGDLKRPFKAAAGLMSGLQSGPAQSDKKAVEAAERAGRGGAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0M0</accession>
    <name>G4N0M0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">YjfJ protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0145 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712958.1">
        <property type="nucleotide sequence ID" value="XM_003712910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0M0"/>
    <dbReference type="SMR" id="G4N0M0"/>
    <dbReference type="GeneID" id="2683674"/>
    <dbReference type="KEGG" id="mgr:MGG_07747"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07747"/>
    <dbReference type="eggNOG" id="ENOG502SDKT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117144_1_1_1"/>
    <dbReference type="InParanoid" id="G4N0M0"/>
    <dbReference type="OMA" id="WTEICAY"/>
    <dbReference type="OrthoDB" id="68104at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.70">
        <property type="entry name" value="Hypothetical protein apc22750. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00338">
        <property type="entry name" value="UPF0145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145_YbjQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068:SF2">
        <property type="entry name" value="UPF0145 PROTEIN SCO3412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068">
        <property type="entry name" value="UPF0145 PROTEIN YBJQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="YbjQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="15922" checksum="8038CBA7EB50FB9E" modified="2011-12-14" version="1">MSTNSGPQPTETPTRPDMQDLHCYTETNGVITTTMFDVPGYRVVRVLGVVYGLTVRSRNWATGTGMVLKSVIGGELRGFTTLLYSARNDAIGRLVAETQSRGGNAVVAMHFESGELGGFSQVCAYGTAAVVEKIDPAVEVHPQLAEASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0M9</accession>
    <name>G4N0M9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_16920</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712967.1">
        <property type="nucleotide sequence ID" value="XM_003712919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0M9"/>
    <dbReference type="SMR" id="G4N0M9"/>
    <dbReference type="STRING" id="242507.G4N0M9"/>
    <dbReference type="GeneID" id="12985877"/>
    <dbReference type="KEGG" id="mgr:MGG_16920"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16920"/>
    <dbReference type="eggNOG" id="KOG3168">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076902_1_1_1"/>
    <dbReference type="InParanoid" id="G4N0M9"/>
    <dbReference type="OMA" id="KMINYRM"/>
    <dbReference type="OrthoDB" id="2020720at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000047">
        <property type="entry name" value="Small nuclear ribonucleoprotein SmB, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="5"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="143"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA53160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="205" mass="20494" checksum="20A5E78BC3F0E65F" modified="2011-12-14" version="1">MAASNKQGKMAGYINYRMRVTLNDGRQMVGQMMAFDKHMNLVLADTEEFRKIKRKQAKPAAPGASGASSSTVESEEKRTLGLTIVRGAQIVSLSVESPPPADPSARLGKATTGGIASTLTAGPGAARPAARGAAAPISLAGPAAGVGGAPPPGFPGFPGAGAPGFPPPGAPGFPPPGAFPPGFQPPPGFGGRGQGPPGFNPPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0U8</accession>
    <name>G4N0U8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712133.1">
        <property type="nucleotide sequence ID" value="XM_003712085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0U8"/>
    <dbReference type="GeneID" id="2684157"/>
    <dbReference type="KEGG" id="mgr:MGG_05818"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05818"/>
    <dbReference type="HOGENOM" id="CLU_1835535_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0U8"/>
    <dbReference type="OrthoDB" id="5208826at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466429" description="Apple domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15788" checksum="D31AECB7B2E52BF9" modified="2011-12-14" version="1">MASKYLIFAFFSILITLTAAFTCTNCAALELRPPSTGMPWDKDGSSSQHVATPSKRDDAQLIQPDGPHQTAKLGYKTELTKECAQACLKTCRPFDFLPYEYADCRLVPTRLGKNEKGVGNPNQNYRKTRTKDRKWKHEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N143</accession>
    <name>G4N143_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucanase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_07809</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.91"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 7 (cellulase C) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713026.1">
        <property type="nucleotide sequence ID" value="XM_003712978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N143"/>
    <dbReference type="SMR" id="G4N143"/>
    <dbReference type="STRING" id="242507.G4N143"/>
    <dbReference type="GeneID" id="2683736"/>
    <dbReference type="KEGG" id="mgr:MGG_07809"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07809"/>
    <dbReference type="eggNOG" id="ENOG502QPHV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020817_3_2_1"/>
    <dbReference type="InParanoid" id="G4N143"/>
    <dbReference type="OMA" id="TQFFVQN"/>
    <dbReference type="OrthoDB" id="412382at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016162">
        <property type="term" value="F:cellulose 1,4-beta-cellobiosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07999">
        <property type="entry name" value="GH7_CBH_EG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.100.10">
        <property type="entry name" value="Glycoside hydrolase, family 7, domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001722">
        <property type="entry name" value="Glyco_hydro_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037019">
        <property type="entry name" value="Glyco_hydro_7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753">
        <property type="entry name" value="1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33753:SF2">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00840">
        <property type="entry name" value="Glyco_hydro_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00734">
        <property type="entry name" value="GLHYDRLASE7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465928" description="Glucanase" evidence="11">
        <location>
            <begin position="20"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA53219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="448" mass="48456" checksum="5D2A917CFA2D155D" modified="2011-12-14" version="1">MQLTKAGVFLGALMGGAAAQQVGTQTAENHPKMTWKKCTGKASCTTVNGEVVIDANWRWLHDASSKNCYDGNRWTDSCRTASDCAAKCSLEGADYAKTYGASTSGDALSLKFVTRHDYGTNIGSRFYLMNGASKYQMFSLLGNEFAFDVDLSTIECGLNSALYFVAMEEDGGMKSYSSNKAGAKYGTGYCDAQCARDLKFVGGKANIEGWKPSSNDANAGVGPYGACCAEIDVWESNAHAFAFTPHPCTDNKYHVCQDSNCGGTYSDDRFAGKCDANGCDINPYRLGNTDFYGKGKTVDTSKKFTVVTRFERDALTQFFVQNNKRIDMPSPALEGLPATGAITAEYCTNVFNVFGDRNRFDEVGGWSQLQQALSLPMVLVMSIWDDHYSNMLWLDSVYPPDKEGSPGAARGDCPQDSGVPSEVESQIPGATVVWSNIRFGPVGSTVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1D1</accession>
    <name>G4N1D1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16794</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712209.1">
        <property type="nucleotide sequence ID" value="XM_003712161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1D1"/>
    <dbReference type="GeneID" id="12984929"/>
    <dbReference type="KEGG" id="mgr:MGG_16794"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16794"/>
    <dbReference type="HOGENOM" id="CLU_2979575_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1D1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="58" mass="6077" checksum="31541417CD7B85C1" modified="2011-12-14" version="1">MAMSNCDARDLSKALGLPTLRRNLSATDCTCQGFEVSAGRGVEAGTSSGGTHTTRLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1M9</accession>
    <name>G4N1M9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Geranylgeranyl pyrophosphate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_13405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711408.1">
        <property type="nucleotide sequence ID" value="XM_003711360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1M9"/>
    <dbReference type="SMR" id="G4N1M9"/>
    <dbReference type="STRING" id="242507.G4N1M9"/>
    <dbReference type="GeneID" id="5050328"/>
    <dbReference type="KEGG" id="mgr:MGG_13405"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13405"/>
    <dbReference type="eggNOG" id="KOG0777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_10_0_1"/>
    <dbReference type="InParanoid" id="G4N1M9"/>
    <dbReference type="OMA" id="FSWEREY"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046165">
        <property type="term" value="P:alcohol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF72">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G01210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="364"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="396"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA51601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="728" mass="82727" checksum="0CAD55604BE00D54" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3K2</accession>
    <name>G4N3K2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pumilio homology domain family member 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_04985</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PUF3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712484.1">
        <property type="nucleotide sequence ID" value="XM_003712436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3K2"/>
    <dbReference type="SMR" id="G4N3K2"/>
    <dbReference type="STRING" id="242507.G4N3K2"/>
    <dbReference type="GeneID" id="2675566"/>
    <dbReference type="KEGG" id="mgr:MGG_04985"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04985"/>
    <dbReference type="eggNOG" id="KOG1488">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004017_4_0_1"/>
    <dbReference type="InParanoid" id="G4N3K2"/>
    <dbReference type="OMA" id="SHTYGCR"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="PHI-base" id="PHI:882"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000004">
        <property type="entry name" value="Pumilio homolog 1 isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF12">
        <property type="entry name" value="MATERNAL PROTEIN PUMILIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="10">
        <location>
            <begin position="470"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="492"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="528"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="564"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="600"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="636"/>
            <end position="671"/>
        </location>
    </feature>
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        <location>
            <begin position="672"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="8">
        <location>
            <begin position="749"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="54"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="224"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="355"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="831"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
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        <location>
            <begin position="367"/>
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        </location>
    </feature>
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        <location>
            <begin position="831"/>
            <end position="840"/>
        </location>
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        <location>
            <begin position="841"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00060736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00081811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA52677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="888" mass="96858" checksum="576BACE6E175044F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N437</accession>
    <name>G4N437_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003712516.1"/>
    </dbReference>
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    <dbReference type="STRING" id="242507.G4N437"/>
    <dbReference type="GeneID" id="2675346"/>
    <dbReference type="KEGG" id="mgr:MGG_05052"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05052"/>
    <dbReference type="eggNOG" id="ENOG502RMIF">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_573734_0_0_1"/>
    <dbReference type="InParanoid" id="G4N437"/>
    <dbReference type="OMA" id="HRMASDK"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        </location>
    </feature>
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            <end position="421"/>
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        </location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="476" mass="53135" checksum="91FDD4D340A2C4D4" modified="2011-12-14" version="1">MDMFHNFRETFFGTPRSRVPAPMDMNMGKVPATAPQRKRKANDDLHVTTSSQQTKRGYGRASRRLYDASKSSPLSAVSAESSRLSFVSRSQVTVTVPESPHKPTIESAADGSIVVANDLHYAQDEEDADEADGNVDEPVEANDVSMPPRAVSVELLSSPSRSNRASGLPKRGSARLPSPEILEPKRARKSATEEPEQSRQDQNAQSEAEDCEDDNEDKSVRHESEPAVPARTLEHDGKGAEGDNGLDANDEELGRDEPLDATAPSPTKATPPRPESTRSDNQEEFPEMPDDGIVLLQPDSEAMPIVLYDDVSNERYTIKAILKHRPNKHIKHSFELQISWVGYKEPSWEPERSIQAQAPELLYKYWSDLGGRPETGAFRVFMILRHWTDPEAAKGRRGRPSKKKQAETETQAPTAAGSITGRIKTKTKYEVQWEGYPNEKQCNSVETDMRLSKIAPEELAVYWEHFESQSKVENTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5D6</accession>
    <name>G4N5D6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_12902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712800.1">
        <property type="nucleotide sequence ID" value="XM_003712752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5D6"/>
    <dbReference type="GeneID" id="5048839"/>
    <dbReference type="KEGG" id="mgr:MGG_12902"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12902"/>
    <dbReference type="HOGENOM" id="CLU_1151977_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5D6"/>
    <dbReference type="OMA" id="WSKETEW"/>
    <dbReference type="OrthoDB" id="10405191at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="241" mass="27416" checksum="F6914268A396D925" modified="2011-12-14" version="1">MRLIQAFKSERLSFINRFPGPLNAPTSPNYCNPDMWSGPLRPYALFDVRYRGPDTLGRIGWERLASRKRELVKNACYTHGYLVGAAISLIPLVWLHEDPGAMNQILAKLTEDMTFVSGAAFASTTVGLSFDKLLKKLRRLWHSEKLSSYREKALAAIEKTNKLFVAAWLVQGAMWSKETEWQLYSLCLNPKELIFTSNADIFIDVAVAQSRMLAIKDHVLDERLRAMWPMPVVYDDASDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N635</accession>
    <name>G4N635_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-dependent protein kinase regulator pho80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716078.1">
        <property type="nucleotide sequence ID" value="XM_003716030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N635"/>
    <dbReference type="STRING" id="242507.G4N635"/>
    <dbReference type="GeneID" id="2678669"/>
    <dbReference type="KEGG" id="mgr:MGG_08559"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08559"/>
    <dbReference type="eggNOG" id="ENOG502SCMA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071095_1_0_1"/>
    <dbReference type="InParanoid" id="G4N635"/>
    <dbReference type="OMA" id="ADIFYWP"/>
    <dbReference type="OrthoDB" id="1894652at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219:SF1">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466162" description="Cyclin-dependent protein kinase regulator pho80" evidence="1">
        <location>
            <begin position="20"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="20702" checksum="D4E2B29189A61B7F" modified="2011-12-14" version="1">MILQHVLALLAAAAPLALAEPQTAAIYIQPISSSTIPPAPLAEITYDPAEASDPTGQVTSFEPPELPESTSLVRIGVFDAAADEWLSSTSVASVDNFSKGYSPHFVLTLGPGAGGEGPVAVIGAAVKGVKVDAGATRDFGPQAVLVSGERAPQPALNRPVVLNKDGAGRAGEVEEKTFLQKYWWALGLLAFVMITGGGPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6M0</accession>
    <name>G4N6M0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717008.1">
        <property type="nucleotide sequence ID" value="XM_003716960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6M0"/>
    <dbReference type="GeneID" id="12985528"/>
    <dbReference type="KEGG" id="mgr:MGG_17172"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17172"/>
    <dbReference type="HOGENOM" id="CLU_2904650_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6M0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="62" mass="6800" checksum="E013A974AA33EE9F" modified="2011-12-14" version="1">MRNIFCNNKFRGSSSAKLVLYARYGNIGCQQPSELVPLCIPVAIRRKTNRSGAAVTKNNQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6M7</accession>
    <name>G4N6M7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL28m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_14858</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717015.1">
        <property type="nucleotide sequence ID" value="XM_003716967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6M7"/>
    <dbReference type="SMR" id="G4N6M7"/>
    <dbReference type="FunCoup" id="G4N6M7">
        <property type="interactions" value="193"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N6M7"/>
    <dbReference type="GeneID" id="5049178"/>
    <dbReference type="KEGG" id="mgr:MGG_14858"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14858"/>
    <dbReference type="eggNOG" id="KOG3278">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064548_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6M7"/>
    <dbReference type="OMA" id="MLRWRIM"/>
    <dbReference type="OrthoDB" id="361870at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.40:FF:000003">
        <property type="entry name" value="54S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_bL28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="251" mass="28233" checksum="325CDF4C713B23A4" modified="2011-12-14" version="1">MPPSRALAGGVAFLSSAARGSRASTSALRQFTTTTASPYKQPKGPATRELPIPSPSAQHPEIPAYPFGPRATYKQSNKGLYGSASIRFGNNVSEKYNVKTRRKWRPNVQTRRLYSESLGQMIRTRVTTRVLRTIDKVGGLDNYLLGTKTQRLKDLGPWGWRLRWRIMQTPKVRAMFARQREELGLPPQGAVQEFLPEGETAESLMRQTDEMLSREDEFEIGEQEADVHVDVVPDNFMAEEKRPSGAEVKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6M9</accession>
    <name>G4N6M9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aspartate aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_06530</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717017.1">
        <property type="nucleotide sequence ID" value="XM_003716969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6M9"/>
    <dbReference type="SMR" id="G4N6M9"/>
    <dbReference type="STRING" id="242507.G4N6M9"/>
    <dbReference type="GeneID" id="2684685"/>
    <dbReference type="KEGG" id="mgr:MGG_06530"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06530"/>
    <dbReference type="eggNOG" id="KOG1411">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032440_1_2_1"/>
    <dbReference type="InParanoid" id="G4N6M9"/>
    <dbReference type="OMA" id="VGACTIV"/>
    <dbReference type="OrthoDB" id="6752799at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006533">
        <property type="term" value="P:L-aspartate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000026">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000181">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF22">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="9">
        <location>
            <begin position="35"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA50698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="405" mass="44406" checksum="B88A5A08DCBEC8AF" modified="2011-12-14" version="1">MPRDPRPSRIARDANTFTDCQARITEAFKADSNNKKINLGVGAYRDDAGKPYVLPSVRQAEEKVIAARMNKEYAGITGVPEFTSGALTLAYGKDSTALDRTAITQSISGTGALRIGAEFLSKFYPGAKNIYIPTPSWANHGAVFTQAGLKVEKYRYYNKDTIGLDFEGLVADVKAAPKGSIFLFHACAHNPTGVDPTPEQWREIETVVKSAGHYAFFDMAYQGFASGDIHKDAFALRHFVAQGHNVCLAQSFAKNMGLYGERVGAFSIVCDSAEEKKRVDSQLKILVRPMYSNPPIHGARIAAQILNTPALYDQWLAEVKGMADRIITMRALLKENLEKLGSKHDWSHITSQIGMFAYTGLTPEQMEQLAKSHSVYATKDGRISVAGITSENVGRLAEAIFKIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7C7</accession>
    <name>G4N7C7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">mitochondrial processing peptidase</fullName>
            <ecNumber evidence="5">3.4.24.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Beta-MPP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_03600</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.</text>
            <dbReference type="EC" id="3.4.24.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="5"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716305.1">
        <property type="nucleotide sequence ID" value="XM_003716257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7C7"/>
    <dbReference type="SMR" id="G4N7C7"/>
    <dbReference type="FunCoup" id="G4N7C7">
        <property type="interactions" value="890"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7C7"/>
    <dbReference type="MEROPS" id="M16.003"/>
    <dbReference type="GeneID" id="2676683"/>
    <dbReference type="KEGG" id="mgr:MGG_03600"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03600"/>
    <dbReference type="eggNOG" id="KOG0960">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_4_2_1"/>
    <dbReference type="InParanoid" id="G4N7C7"/>
    <dbReference type="OMA" id="IDVVCDM"/>
    <dbReference type="OrthoDB" id="10251424at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017087">
        <property type="term" value="C:mitochondrial processing peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000002">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000001">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="16">
        <location>
            <begin position="49"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="17">
        <location>
            <begin position="201"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA49986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="473" mass="52307" checksum="8DFE429FB45F5B00" modified="2011-12-14" version="1">MASRRLALNLSKGLRARAGLSMPMRRGFATPVPTPAGTQTTTLKNGLTVATQYSPYAQTSTVGMWIDAGSRAETNENNGTAHFLEHLAFKGTQRRTQHQLELEIENMGAHLNAYTSRENTVYFAKSLNEDAPKCVDILADILQNSKLDEAAIERERDVILRESEEVEKQLEEVVFDHLHATAFQHQPLGRTILGPRENIRDITRTELVNYIKQNYTADRMVLAAAGGVPHEQLVELADKYFANLPGETAKTSAYIQSKAKPDFIGSDVRIRDDTIPTANIAIAVEGVSWSDDDYFTALVTQAIVGNYDKAMGNAPHQGSKLSGFVHSNDLANSFMSFSTSYSDTGLWGIYLVTDKLTRVDDLVHFALREWSRLSQSVSEAEVERAKAQLKASILLSLDGTTAVAEDIGRQIVTTGRRMNPAEIERVIDAVTAKDVMSFAQRKLWDKDVAVSAVGSIEGLFDYARIRGDMSRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7E6</accession>
    <name>G4N7E6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716324.1">
        <property type="nucleotide sequence ID" value="XM_003716276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7E6"/>
    <dbReference type="SMR" id="G4N7E6"/>
    <dbReference type="GeneID" id="2677001"/>
    <dbReference type="KEGG" id="mgr:MGG_03585"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03585"/>
    <dbReference type="eggNOG" id="ENOG502SSSQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141129_1_0_1"/>
    <dbReference type="InParanoid" id="G4N7E6"/>
    <dbReference type="OMA" id="NLQCNVD"/>
    <dbReference type="OrthoDB" id="3178264at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465884" description="Cell wall protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="13954" checksum="71CEC6286310F18E" modified="2011-12-14" version="1">MHAQQYIIAALMAFGAAVTEARALEPRQLGDLACNVARLQIVNALSATKKNVGDIQDPTVKAGAQAGLKQSQDAIGVIGKAIISGSKAPANARDDVAAGLTATGTALQGGSKDDKAVADATSNLTKAAKAGQDVVAKCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7L4</accession>
    <name>G4N7L4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione S-transferase kappa</fullName>
            <ecNumber evidence="4">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_06383</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GST superfamily. Kappa family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717190.1">
        <property type="nucleotide sequence ID" value="XM_003717142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7L4"/>
    <dbReference type="SMR" id="G4N7L4"/>
    <dbReference type="STRING" id="242507.G4N7L4"/>
    <dbReference type="GeneID" id="2684538"/>
    <dbReference type="KEGG" id="mgr:MGG_06383"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06383"/>
    <dbReference type="eggNOG" id="ENOG502RH77">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069253_1_0_1"/>
    <dbReference type="InParanoid" id="G4N7L4"/>
    <dbReference type="OMA" id="PFWGFDR"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03021">
        <property type="entry name" value="DsbA_GSTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000096">
        <property type="entry name" value="Glutathione S-transferase kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051924">
        <property type="entry name" value="GST_Kappa/NadH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044088">
        <property type="entry name" value="GSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014440">
        <property type="entry name" value="HCCAis_GSTk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42943">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42943:SF13">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE KAPPA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006386">
        <property type="entry name" value="HCCAis_GSTk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DSBA-like thioredoxin" evidence="6">
        <location>
            <begin position="6"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="240" mass="26870" checksum="BECE30BD6A4D3B8E" modified="2011-12-14" version="1">MANGKIQCFLDIASYFSYIAFADLLPNLDLLAAHGVEVEFVPVLIAGINTQSGNKPPWTLQAKAEYLRYDSDRAKERVGKAGIAFPKDFLSMALTVLPQRAMHYIKRNYSTKQYLTAMHYLFHAFWTPPHKNLTKQDVLREVLASVPSDFPGQGAPLFSSQEVDDIIKAAGTQEYKDALTSSTDEAVAKGAFGAPWIFVTNARGAEEPFFGSDRFNHIYKFLDLPFRDIELLPPTKESKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7Y3</accession>
    <name>G4N7Y3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716404.1">
        <property type="nucleotide sequence ID" value="XM_003716356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7Y3"/>
    <dbReference type="GeneID" id="12984449"/>
    <dbReference type="KEGG" id="mgr:MGG_17081"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17081"/>
    <dbReference type="HOGENOM" id="CLU_1454705_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7Y3"/>
    <dbReference type="OrthoDB" id="10609782at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="186" mass="20556" checksum="B8343C6A474F5B2B" modified="2011-12-14" version="1">MNKSRQISVKKVSPSIFLVDIGTGSGERSRQLDLGGTGEPRTCYWNETDRVQVPIVRTLPADVSNMVRRMREKRRTASPTWKYFGTAKRTAKAGICPIAITFSPASANRDRRGDLVRIGTDGKVRSVCECLLADVLCIHCQQEKNKKGKVINRLIGIRKFDAETTRGTNAASPGCDFTDDLGERPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N803</accession>
    <name>G4N803_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716424.1">
        <property type="nucleotide sequence ID" value="XM_003716376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N803"/>
    <dbReference type="SMR" id="G4N803"/>
    <dbReference type="STRING" id="242507.G4N803"/>
    <dbReference type="GeneID" id="2676692"/>
    <dbReference type="KEGG" id="mgr:MGG_03498"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03498"/>
    <dbReference type="eggNOG" id="ENOG502S28H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064561_0_0_1"/>
    <dbReference type="InParanoid" id="G4N803"/>
    <dbReference type="OMA" id="YPAKGFQ"/>
    <dbReference type="OrthoDB" id="17725at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051599">
        <property type="entry name" value="Cell_Envelope_Assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30336:SF20">
        <property type="entry name" value="DUF218 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30336">
        <property type="entry name" value="INNER MEMBRANE PROTEIN, PROBABLE PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="32"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="155"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="260" mass="29529" checksum="BE17203F2DF9EB82" modified="2011-12-14" version="1">MATAQANRAYSDAEMVYNYHRMNMPLHQPADAIFCLCSLDTRVAERAAQLLLDGFAGADGVLIFSGGSGKLTETRFSEPEAEVFAAVARRMGVPPARILVEPRSSNTGENVRFTRALLRDRGLSPRSFILVQKPYMERRTYATFVKQWSCSGVGDEEAQEDGESLQQQQQQQQQQQQQQKQQEKQQQQQPVFTVTSPQMTFAEYPDQDNPRDLVISIMVGDLVRIREYPARGFQISQEIPDEVWEAGQRLIREGYNIHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N870</accession>
    <name>G4N870_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717290.1">
        <property type="nucleotide sequence ID" value="XM_003717242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N870"/>
    <dbReference type="GeneID" id="12985633"/>
    <dbReference type="KEGG" id="mgr:MGG_17194"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17194"/>
    <dbReference type="HOGENOM" id="CLU_2347106_0_0_1"/>
    <dbReference type="InParanoid" id="G4N870"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="97" mass="11151" checksum="7F968B5DB6786F7F" modified="2011-12-14" version="1" fragment="single">LGLSDLSVLLPVCHLTDALKSHRQRRTRNHERIRPVCCMLEEHKRRCIHYRRFCPIEVSSSRLKEDRRVGFGLGGDHTAWIDSSAPDHQGGPPIESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8G0</accession>
    <name>G4N8G0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">prephenate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_14843</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="2"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717327.1">
        <property type="nucleotide sequence ID" value="XM_003717279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8G0"/>
    <dbReference type="SMR" id="G4N8G0"/>
    <dbReference type="FunCoup" id="G4N8G0">
        <property type="interactions" value="120"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N8G0"/>
    <dbReference type="GeneID" id="5048785"/>
    <dbReference type="KEGG" id="mgr:MGG_14843"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14843"/>
    <dbReference type="eggNOG" id="KOG2797">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035008_5_1_1"/>
    <dbReference type="InParanoid" id="G4N8G0"/>
    <dbReference type="OMA" id="PLMIYRE"/>
    <dbReference type="OrthoDB" id="983542at2759"/>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04905">
        <property type="entry name" value="ACT_CM-PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13532">
        <property type="entry name" value="PBP2_PDT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022">
        <property type="entry name" value="PREPHENATE DEHYDRATASE P PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21022:SF19">
        <property type="entry name" value="PREPHENATE DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="8">
        <location>
            <begin position="230"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA51008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="311" mass="33216" checksum="C4BE7D5176D1CC85" modified="2011-12-14" version="1">MTVVQTRSEPANHGSSVAYLGPPASYSHQATTSLFPGKEWSLVPTATIKGVFDMVQSGNAAYGVVPFENSTHGVVTFTLDSLGDRAGEFADVSVCGEVYLDVQHFLLGRRDPTADDPNSLAHIRHVYSHPQAFGQTQGFTSTRLAHAELVDVSSTSRGAEMAAADASRTSAAVASEMAAAATGLDILARSIQDRGDNTTRFLVLRRGRPSVARQDASFAVAAAAATKSLVSFTVPHRCPGALAEVLQCFQRHGLDLTSINSLPSLIQPFQYLFFVEFEAADRAESSIAVVLEDVARVAQSSRWLGSWGSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N935</accession>
    <name>G4N935_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M50B-like-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_10057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
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                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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    </feature>
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    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
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    </evidence>
    <sequence length="288" mass="31266" checksum="E6EC6E3C827B655F" modified="2011-12-14" version="1">MAPTPETLASTVKLARSAALAAAPLAARHLMETSALHKRERPPGSLSVTDTQKVTLGVIAAYTVAIAILWNVPFLRWSLWPFKMLVIAFHEFGHASTACCTGGRVESIKLDPREGGVTMMRGGISAITLPAGYLGSSLIGALLIFCGFDIIASKVVSFVLAVCFLLTLWWGKKDWLTIFTVLLAVGLLVACWFIAHAQALRFFVLFIGVMSSLYSVWDICDDLILRKVNESDASQFAKRYGGSSQCWGVIWSIISLAFMAAGIVAGIAAFPDSFAEQNEKSQRFLPTR</sequence>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <source>
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    </evidence>
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            <dbReference type="EMBL" id="EHA51186.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="264" mass="25465" checksum="BA08DC7100AB06A6" modified="2011-12-14" version="1">MRFSSVFALSALIQAAVSAPIPSGTGTGNAVNAITDAATDSTPLKVATGVTATGGALYGLTGQGLASGVANGQAAVEAGEKTQAIGEEIGSRETQLAGLKDKQAGRKVATKGQTATNLNPVKGFQVWKEGGDVRRKAEGNLENAENDKAGIPRPGASGCKRSLGSACNNPALASGSSGNPSAAAAAAAKNGQNAAPAQKPAAAAALAQKPAAAAALAQKPAAAAALAQKPAAAAALAQKPAAAAANKIPPVRSGPVKPAGKGRV</sequence>
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    <accession>G4N9T7</accession>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Donofrio N."/>
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                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
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                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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            <dbReference type="EMBL" id="EHA49594.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717570.1">
        <property type="nucleotide sequence ID" value="XM_003717522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA05"/>
    <dbReference type="GeneID" id="12986571"/>
    <dbReference type="KEGG" id="mgr:MGG_17265"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17265"/>
    <dbReference type="HOGENOM" id="CLU_3129774_0_0_1"/>
    <dbReference type="InParanoid" id="G4NA05"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017854">
        <property type="entry name" value="Metalthion_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57868">
        <property type="entry name" value="Metallothionein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0480">Metal-thiolate cluster</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="50" mass="5263" checksum="E5370EF20DC62E49" modified="2011-12-14" version="1">MAGNCGCSGASSCNCGDKWTRRAALTLQYGTWLSSARTPRLARQRGVGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA69</accession>
    <name>G4NA69_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_15347</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715938.1">
        <property type="nucleotide sequence ID" value="XM_003715890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA69"/>
    <dbReference type="SMR" id="G4NA69"/>
    <dbReference type="STRING" id="242507.G4NA69"/>
    <dbReference type="GeneID" id="12986822"/>
    <dbReference type="KEGG" id="mgr:MGG_15347"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15347"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_6_3_1"/>
    <dbReference type="InParanoid" id="G4NA69"/>
    <dbReference type="OMA" id="FHDHLHM"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF115">
        <property type="entry name" value="DEHYDROGENASE XPTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466355" evidence="3">
        <location>
            <begin position="17"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="4">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="542"/>
            <end position="543"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA49619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="609" mass="66473" checksum="C3ACC9BF232A03EA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAU0</accession>
    <name>G4NAU0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716851.1">
        <property type="nucleotide sequence ID" value="XM_003716803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAU0"/>
    <dbReference type="GeneID" id="12985435"/>
    <dbReference type="KEGG" id="mgr:MGG_17138"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17138"/>
    <dbReference type="HOGENOM" id="CLU_2210558_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAU0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="107" mass="11698" checksum="7C375E32AE44DD07" modified="2011-12-14" version="1">MGGTRTGALLARGMSGMDGPGSLNRQRGKKKSGFIGQTSKAGTIGPYCIYRYRTMSCESFRLPPESGNCSADKDLDLGIELDFSRRVQKRRAVRVVDSIPEPSKIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBH9</accession>
    <name>G4NBH9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 13">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="8 13">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_00534</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="15">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; pentose phosphate pathway; D-xylulose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 13">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="8 13"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718520.1">
        <property type="nucleotide sequence ID" value="XM_003718472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBH9"/>
    <dbReference type="SMR" id="G4NBH9"/>
    <dbReference type="FunCoup" id="G4NBH9">
        <property type="interactions" value="446"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NBH9"/>
    <dbReference type="GeneID" id="2674640"/>
    <dbReference type="KEGG" id="mgr:MGG_00534"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00534"/>
    <dbReference type="eggNOG" id="KOG3111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054856_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBH9"/>
    <dbReference type="OMA" id="CHLMIED"/>
    <dbReference type="OrthoDB" id="1927044at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00411"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000130">
        <property type="entry name" value="Ribulose-phosphate 3-epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004076">
        <property type="entry name" value="PRK05581.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12 15" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="10 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="173"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="224"/>
            <end position="225"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA48936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="251" mass="26770" checksum="ACB3AC4614BA6611" modified="2011-12-14" version="1">MAPQAIIAPSILSADFGNLGEECSKTIGQGADWLHVDIMDGHFVPNITFGPPVVAKIRGHVDRPEAAHGKGTFDCHMMIAEPKKWVKEFKAAGCDLYCFHYEAAFSSAAEEPSATSDAKTSPRELIRYIHDQGLLAGIAIKPATPADVLYELLDSSDAAERPDMVLVMTVEPGFGGQKFMASELPKVQALRQRYPELNIEVDGGLGPGTIDQAADAGANVIVAGSAVFGAKDPAEVIKVLRESVQKRAGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCE2</accession>
    <name>G4NCE2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718675.1">
        <property type="nucleotide sequence ID" value="XM_003718627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCE2"/>
    <dbReference type="SMR" id="G4NCE2"/>
    <dbReference type="STRING" id="242507.G4NCE2"/>
    <dbReference type="GeneID" id="2674945"/>
    <dbReference type="KEGG" id="mgr:MGG_00401"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00401"/>
    <dbReference type="eggNOG" id="ENOG502TJRC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062263_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCE2"/>
    <dbReference type="OMA" id="THDWEHI"/>
    <dbReference type="OrthoDB" id="89086at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008701">
        <property type="entry name" value="NPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33657:SF6">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05630">
        <property type="entry name" value="NPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029958">
        <property type="entry name" value="Necrosis-inducing_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="264" mass="29182" checksum="8E61AF287B3EDA23" modified="2011-12-14" version="1">MPKPASCGASPVPDDMLNMHKLLRREPPKALPQNASAPELRWQPTMDFDKDGCYNTPAMDGTGKITPGLNNMFTGTDTGCRDASDLDNNNVYVRSRCNNGWCVFLYDYYFEKDVALPYLPDVGHRHDWEHVAVFVEGGDRARLVAASAHGGYATRQADEVRWDGDHPKMVYHKDGIGTHCFRFGSEADDGKIENHRGKWFLGSLVSFDGFPSTQLRDKLFSHDFGAATIGIKDSQFQSNIDKARGKDGAPGFDSSKDDGSGGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCI5</accession>
    <name>G4NCI5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717866.1">
        <property type="nucleotide sequence ID" value="XM_003717818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCI5"/>
    <dbReference type="STRING" id="242507.G4NCI5"/>
    <dbReference type="GeneID" id="2674121"/>
    <dbReference type="KEGG" id="mgr:MGG_01073"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01073"/>
    <dbReference type="eggNOG" id="ENOG502S7KB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_305446_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCI5"/>
    <dbReference type="OMA" id="AGGINEH"/>
    <dbReference type="OrthoDB" id="3539644at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="931"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="949"/>
            <end position="960"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="971" mass="103289" checksum="36ADA0B09DAB24A8" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND68</accession>
    <name>G4ND68_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydrodipicolinate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717994.1">
        <property type="nucleotide sequence ID" value="XM_003717946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND68"/>
    <dbReference type="SMR" id="G4ND68"/>
    <dbReference type="STRING" id="242507.G4ND68"/>
    <dbReference type="GeneID" id="2674255"/>
    <dbReference type="KEGG" id="mgr:MGG_00956"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00956"/>
    <dbReference type="eggNOG" id="ENOG502RFPT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND68"/>
    <dbReference type="OMA" id="QEGIIQW"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF68">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="328" mass="35044" checksum="A5D89C9EE0098C13" modified="2011-12-14" version="1">MAAAPAPGIYVPVPTFFASRTAADYNAHAPPVDVAAQVAHSLYLARAGIHGLVILGSTGEAVHMTNDERTTVLAGVRKGLDAEGFKDYPIIAGTASHSVVEVVEQLKDAHEKAACQFGMVLVPGYFAGATSQEGIVRWFTAVADQSPIPVMIYHYPGVSNNVKVTIPTFAKLSQHPNIVGCKLSYPDVPVHTELALHPEIDHSRFAVFTGLGSQLFPVVAVGGAGAIDGAAAFFPKAVVRLFELSRNVRPTDEEHAERGRLQYLVAALYSKLIPTGTIGIKEAVARLRGFGDPDGTRLPLFGGFADGDAEWARWKPIVDQLEEAEKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDB2</accession>
    <name>G4NDB2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718834.1">
        <property type="nucleotide sequence ID" value="XM_003718786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDB2"/>
    <dbReference type="GeneID" id="2674596"/>
    <dbReference type="KEGG" id="mgr:MGG_00266"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00266"/>
    <dbReference type="eggNOG" id="ENOG502RA2M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_966678_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDB2"/>
    <dbReference type="OMA" id="CWEREGT"/>
    <dbReference type="OrthoDB" id="5243557at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="288" mass="30267" checksum="236188284DB62E4E" modified="2011-12-14" version="1">MSLPRRMPQGAGHQLYSQPKPRPTITWTEGDIAFLIPYSARQSEYDALPVRVPVKATCHPVIILKACSTGSHYVVTTISAYGVSPDGGPAPWAQHAHRFKTAHDFRVFTGTEPYVDASGRHESRAPLTLEPGMRMPKPKTSWVYARTAFLVPASVLGVFNKSPTQLRMTTASLGDLRAHMAQCSSGKSGYRGSVDVNGRVNCACCCGGSPPQQPPVVPVLGLVSPALAAAAGGCGVKSAPGPIRPMPPANAPAGPRSWRPPPAAVPVVSAPTTVVQAPKSWAAIAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2024-01-24" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDJ1</accession>
    <name>G4NDJ1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718860.1">
        <property type="nucleotide sequence ID" value="XM_003718812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDJ1"/>
    <dbReference type="GeneID" id="12985037"/>
    <dbReference type="KEGG" id="mgr:MGG_17494"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17494"/>
    <dbReference type="InParanoid" id="G4NDJ1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="58" mass="6818" checksum="D3A8722D78315DF6" modified="2011-12-14" version="1" fragment="single">RRILNRKLSHIMRTRSKTLQLLMIRPSVLPQLDAFASPSTWQQPTRHGERHWTSINVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDS5</accession>
    <name>G4NDS5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718097.1">
        <property type="nucleotide sequence ID" value="XM_003718049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDS5"/>
    <dbReference type="GeneID" id="12984017"/>
    <dbReference type="KEGG" id="mgr:MGG_17353"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17353"/>
    <dbReference type="HOGENOM" id="CLU_2654981_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDS5"/>
    <dbReference type="OMA" id="FYVRRAC"/>
    <dbReference type="OrthoDB" id="5206627at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466122" evidence="1">
        <location>
            <begin position="20"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="76" mass="8197" checksum="AE5CD6EF16D70518" modified="2011-12-14" version="1">MRFSAITSVAITMLGFAAAKPTESHGVASGKYLFSRSTTACDCDGVRGCCINDCNFNENCCNTTCMDRFPECYNAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEP8</accession>
    <name>G4NEP8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc-binding alcohol dehydrogenase domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_00738</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718262.1">
        <property type="nucleotide sequence ID" value="XM_003718214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEP8"/>
    <dbReference type="SMR" id="G4NEP8"/>
    <dbReference type="STRING" id="242507.G4NEP8"/>
    <dbReference type="GeneID" id="2674555"/>
    <dbReference type="KEGG" id="mgr:MGG_00738"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00738"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_1"/>
    <dbReference type="InParanoid" id="G4NEP8"/>
    <dbReference type="OMA" id="WAEVPDP"/>
    <dbReference type="OrthoDB" id="203908at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF18">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="15"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="343" mass="36706" checksum="7BF6923B1B9DFE0C" modified="2011-12-14" version="1">MPETMKAVDVRGGAGPASALFINAETPRPTPGAGQVLVKVSAFGLNRMDLLQREGKYPLPPQAPKTLGVEFSGVIESLGDFSASASTDADGIPFKKGDAVFGLAYGDAYAEYIAVSARMLMHKPAGLTHEQAAGIPETFITATQALHLVGGFAKGDRVLWHAGASGVSIAGAQLARRAGAGAVFSTAGSDDKCAFLREELGVDGAFNYKTQDWAEEVRRATGGRGVDLIVDFVGADYFSKNMDAAAQEGRIVCLGLLSGAVVKEVNVAQLLFKRLRIEGSTLRARDEEYQGMLRDRLEECLPQFETGELKVFVDKVLSWEQIQEAHELLEKNVTRGKIICTIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFD0</accession>
    <name>G4NFD0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_12203</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719525.1">
        <property type="nucleotide sequence ID" value="XM_003719477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFD0"/>
    <dbReference type="GeneID" id="2677586"/>
    <dbReference type="KEGG" id="mgr:MGG_12203"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12203"/>
    <dbReference type="eggNOG" id="ENOG502RW31">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_12_0_1"/>
    <dbReference type="InParanoid" id="G4NFD0"/>
    <dbReference type="OMA" id="KRFAPKW"/>
    <dbReference type="OrthoDB" id="5342292at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF124">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="58"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="341"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="376" mass="41038" checksum="54B2A46D29DFCB39" modified="2011-12-14" version="1">MSANSSTVFPEVDGVTVFALPPKGYTPDLKSPAEQSALAHFLIFGIVGFLAFIALCQRMFTKIFLIKAIHIEDWFMCIAWIFSMVMQSSQIHSIVIGGLCHHTWEMPIEVFESSMIVSYIAAPSFILCNGFTKISILLFYRKIAPTPWFHRMIWATICAVSLYTTIIASMLLFGCRPIRSFWVPELLGTGHCLDAAVLYMAIAVSNIASDYILFILPIPIISPLKMRWAQKLGALFILSIASFTVITSVIRLQLLPALLTSTDISWDAGPANVWSILEANLFIICGSMPTLSKFAKHFWAPFRDSSSRGPSGGDGYGGNIRLRRHSFGIGSATHELGVIKASSSMGPKNGNSGSGPSLSSSRTSGMADSSTQLTDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFI1</accession>
    <name>G4NFI1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_08816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719155.1">
        <property type="nucleotide sequence ID" value="XM_003719107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFI1"/>
    <dbReference type="GeneID" id="2678982"/>
    <dbReference type="KEGG" id="mgr:MGG_08816"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08816"/>
    <dbReference type="HOGENOM" id="CLU_1722732_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFI1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="152" mass="16584" checksum="ED0501E0928165FE" modified="2011-12-14" version="1">MTDLPSGQWCGGRWSGMIVDPVITRGRCLASGSGRHSVEKIMLNYGANQRNSSCHDPLPDPLLEADEDAFPESSLQEQIDESTQLVNPHAVLAHARVSKKNVAGAQLYHGQQLVAVKRRRQAARDLVVRAGRRAAGPAAMVAVMWQHIVELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFK0</accession>
    <name>G4NFK0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08797</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719174.1">
        <property type="nucleotide sequence ID" value="XM_003719126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFK0"/>
    <dbReference type="SMR" id="G4NFK0"/>
    <dbReference type="GeneID" id="2678963"/>
    <dbReference type="KEGG" id="mgr:MGG_08797"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08797"/>
    <dbReference type="eggNOG" id="ENOG502T628">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144932_1_0_1"/>
    <dbReference type="InParanoid" id="G4NFK0"/>
    <dbReference type="OMA" id="NSSMICG"/>
    <dbReference type="OrthoDB" id="3928926at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.350.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032382">
        <property type="entry name" value="AltA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16541">
        <property type="entry name" value="AltA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51895">
        <property type="entry name" value="AA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466576" description="AA1-like domain-containing protein" evidence="6">
        <location>
            <begin position="18"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="AA1-like" evidence="7">
        <location>
            <begin position="26"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA46807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="152" mass="15754" checksum="E8CE5EF8F7B56936" modified="2011-12-14" version="1">MRFTIVAAAALLGAAIAAPAPQSNPGPRESISIQNFEAINKEQNGPVTSVYFELVSTRAAGVAAFVCRAEAAEGLKSSDILDCSEGPSPDGAYTFTLVSTAGSTFNLKVYHQTAPGAGLWGVVSVEGQCSIESDDSDVLTCRKDQTPGELQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFZ5</accession>
    <name>G4NFZ5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719319.1">
        <property type="nucleotide sequence ID" value="XM_003719271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFZ5"/>
    <dbReference type="GeneID" id="12985764"/>
    <dbReference type="KEGG" id="mgr:MGG_15367"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15367"/>
    <dbReference type="HOGENOM" id="CLU_1970984_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFZ5"/>
    <dbReference type="OrthoDB" id="4733042at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="127" mass="14585" checksum="3B10761C4BB49AFF" modified="2011-12-14" version="1">MDTFDSNQLSGGMEREDGRPRISKWLVLGGATGRLSIDIQILTLPAHSGQRMHPIRQGPCQFLKTQDLNKLLDVFRYQTDEDFISAFRRQMDRELMTGQLMMGFDDSGIWPLEESRVLDYLPRPANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGL1</accession>
    <name>G4NGL1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ER membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA47371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:endoplasmic reticulum membrane"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048309">
        <property type="term" value="P:endoplasmic reticulum inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000921">
        <property type="term" value="P:septin ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013635">
        <property type="entry name" value="Ice2"/>
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    <dbReference type="PANTHER" id="PTHR31726">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466514" evidence="2">
        <location>
            <begin position="21"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="456" mass="50214" checksum="4086E4ED79CA0A08" modified="2011-12-14" version="1">MLWLFQALFSIVFLLSIVLSIPICFDVGGRDAGLAYSLSLFVFYLFYSAAKLATPDNSRFRRALTELIRLSQWVVIPGLLIWSLNRFSVDEALLDAAQSHGHGSGDWVRRAWFGHDTVAQPAAPAATNFHDWFFGSKGVLESMWLGSWDRGLSYSSPLFQLCEGFCTVLVIQAAGQMTRWLVNRGRSDTWVIVLLVISSSILTSAAYFLWRIMKFPQINNIDATLIGVTITSAVFLGAYGISSGRGNPIESALLFAYVVLCVYQIFTDYMPSDPAAAEALAAAQAAQQPEFPPLPPFIMASWSTLRHMLASLPEAFNVSFTFLYAAFQTVTPSVIISLAYRITVFYCATRIIPAVRESGTNALMADPELYGDSSDGATKLLSVLSWFSPSILIAVYTSLLLQHFTVAADSDIGWTLTAGDIGGNPWRWVNVGATMLMYSLELYLGDDEPAAHWKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGP0</accession>
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            <taxon>Sordariomycetes</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719767.1">
        <property type="nucleotide sequence ID" value="XM_003719719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGP0"/>
    <dbReference type="GeneID" id="5049897"/>
    <dbReference type="KEGG" id="mgr:MGG_12142"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12142"/>
    <dbReference type="HOGENOM" id="CLU_2868118_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGP0"/>
    <dbReference type="PHI-base" id="PHI:878"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="64" mass="6988" checksum="0E6DD1CC95EA2CBD" modified="2011-12-14" version="1">MASTVRKRHAGGLNGGLTRLHHGIVYSLPYGRAQIVPFLAPIFTLAFADSPILGQEYIQYKTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGR1</accession>
    <name>G4NGR1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719788.1">
        <property type="nucleotide sequence ID" value="XM_003719740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGR1"/>
    <dbReference type="GeneID" id="12986212"/>
    <dbReference type="KEGG" id="mgr:MGG_17700"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17700"/>
    <dbReference type="HOGENOM" id="CLU_3069192_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGR1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="53" mass="5822" checksum="831652741F0461A9" modified="2011-12-14" version="1">MPIQRPTAELGPGRFILGLPESTTSSVITWDLMNAVTDRRSVLPEHGFEAVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHB9</accession>
    <name>G4NHB9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_03883</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12 14">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="4 14"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719996.1">
        <property type="nucleotide sequence ID" value="XM_003719948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHB9"/>
    <dbReference type="SMR" id="G4NHB9"/>
    <dbReference type="FunCoup" id="G4NHB9">
        <property type="interactions" value="409"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NHB9"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="GeneID" id="2677370"/>
    <dbReference type="KEGG" id="mgr:MGG_03883"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03883"/>
    <dbReference type="eggNOG" id="KOG1387">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017896_1_1_1"/>
    <dbReference type="InParanoid" id="G4NHB9"/>
    <dbReference type="OMA" id="ARLYGWV"/>
    <dbReference type="OrthoDB" id="2276068at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03806">
        <property type="entry name" value="GT4_ALG11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000168">
        <property type="entry name" value="Alpha-1,2-mannosyltransferase (Alg11), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 18" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="17">
        <location>
            <begin position="127"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="16">
        <location>
            <begin position="377"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00056799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA47629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="569" mass="63561" checksum="82568998F201581C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHP0</accession>
    <name>G4NHP0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_03771</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720117.1">
        <property type="nucleotide sequence ID" value="XM_003720069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHP0"/>
    <dbReference type="SMR" id="G4NHP0"/>
    <dbReference type="GeneID" id="2677413"/>
    <dbReference type="KEGG" id="mgr:MGG_03771"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03771"/>
    <dbReference type="eggNOG" id="ENOG502QPXZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_1_0_1"/>
    <dbReference type="InParanoid" id="G4NHP0"/>
    <dbReference type="OMA" id="LFNIETW"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="549" mass="59594" checksum="7E59AA318BF399F9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI39</accession>
    <name>G4NI39_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720266.1">
        <property type="nucleotide sequence ID" value="XM_003720218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI39"/>
    <dbReference type="GeneID" id="12987251"/>
    <dbReference type="KEGG" id="mgr:MGG_17800"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17800"/>
    <dbReference type="HOGENOM" id="CLU_2360142_0_0_1"/>
    <dbReference type="InParanoid" id="G4NI39"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="96" mass="10148" checksum="A6FB32A3F60B0346" modified="2011-12-14" version="1">MLYNSRLRPNKFQHRRPPLLLGGFSLTAAINNGIPNAKTCDEFTASCKSICAGLNATPTVEGCTGTVPTAATRCGCSINKSPPAQKGPQPKRDVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIP8</accession>
    <name>G4NIP8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Calcium-proton exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_04159</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719671.1">
        <property type="nucleotide sequence ID" value="XM_003719623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIP8"/>
    <dbReference type="SMR" id="G4NIP8"/>
    <dbReference type="STRING" id="242507.G4NIP8"/>
    <dbReference type="GeneID" id="2677314"/>
    <dbReference type="KEGG" id="mgr:MGG_04159"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04159"/>
    <dbReference type="eggNOG" id="KOG1397">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008721_4_0_1"/>
    <dbReference type="InParanoid" id="G4NIP8"/>
    <dbReference type="OMA" id="WNPFRHV"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="PHI-base" id="PHI:2104"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000011">
        <property type="entry name" value="Vacuolar calcium ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="523"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="560"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="584"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="218"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="458"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="12"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="611" mass="65614" checksum="1F18ADB5AFE8EE82" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIS3</accession>
    <name>G4NIS3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719697.1">
        <property type="nucleotide sequence ID" value="XM_003719649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIS3"/>
    <dbReference type="SMR" id="G4NIS3"/>
    <dbReference type="FunCoup" id="G4NIS3">
        <property type="interactions" value="56"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NIS3"/>
    <dbReference type="GeneID" id="2677552"/>
    <dbReference type="KEGG" id="mgr:MGG_04134"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04134"/>
    <dbReference type="eggNOG" id="KOG0634">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_6_1"/>
    <dbReference type="InParanoid" id="G4NIS3"/>
    <dbReference type="OMA" id="DFLQWPV"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42858">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42858:SF1">
        <property type="entry name" value="LD15494P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="1">
        <location>
            <begin position="91"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="510" mass="56238" checksum="C2102499430282BC" modified="2011-12-14" version="1">MQPFNIFKLFLRISIAPSLVPHSTIPSPRFGRMTLRTMATTTPKQLDPANAKRQINLIRGWPAPHTLPAEHLRTAADRMLTEPDVFVPGLQYAPDPGFQPLREELARFMAPYYYHSRGRTPDPARICITGGASQNLGCVLSSFTDPGFTKAVWVVAPCYHLSNPIFEDAGFRGRLRAVPEDDEGIDLEWLERGLKEFGSDDPSEPVFKNLAPSRKAYRHVIYCVPTSANPSGKTMSVARREGLVRLAREYDALVISDDVYDFLQWPLGQQRQGSPQQQYIPPLTPPPRLVDIDRDLTDSLGASRFDSGGFGHTVSNGSFSKIIAPGVRTGWAEGTPAFALGLATTGSNKSGGAASQLAAVMIWEMIRTGALAAHIDGTVRPDLQKRHALLLNAVRQHLSPLGVTFEEPKSTYGGYFVWLTLPDSGPSASIVASRALQDENLILAAGSMFQVKGDEDAVRFPRNLRLCFSWENEDTIVEGVERLAGLLKRLQDEPPVEEKDQDEQKSFGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJ36</accession>
    <name>G4NJ36_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CREG-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02758</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720995.1">
        <property type="nucleotide sequence ID" value="XM_003720947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJ36"/>
    <dbReference type="SMR" id="G4NJ36"/>
    <dbReference type="STRING" id="242507.G4NJ36"/>
    <dbReference type="GeneID" id="2682763"/>
    <dbReference type="KEGG" id="mgr:MGG_02758"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02758"/>
    <dbReference type="eggNOG" id="ENOG502RDU8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056802_1_0_1"/>
    <dbReference type="InParanoid" id="G4NJ36"/>
    <dbReference type="OMA" id="ITLSMRW"/>
    <dbReference type="OrthoDB" id="2138282at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273:SF1">
        <property type="entry name" value="ADL397C-AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466406" description="CREG-like beta-barrel domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="CREG-like beta-barrel" evidence="3">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="285" mass="31042" checksum="ED17A45D99CCD014" modified="2011-12-14" version="1">MKLSGILLLLASSAANAAATPGSGGPPPPPNPAYLFSNPPASDSSTRIPTSRESAAMARRILALTPLATFSTVFPASQSHPEVAGIPIGMNDYVADCEEGGDPTILSLKIGTSFRNVAHGSNISLALAWVPPYPPSRRIKSMSWASSLLSFFGVGGSAEEERPDTVPYSAANLPRFSLMGYLERIEPAKHLSVAACYVNTHPDAKYWLPGNPIHEAEWVRLVVTKVYWVGGFGDRAYIGWIPVEEWKDVTREEWESLRLPGEKPGWKEWSTRELADFTDLPQPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKG4</accession>
    <name>G4NKG4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
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                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Bohnert H."/>
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                <person name="Butler J."/>
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                <person name="Ma L.J."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15</strain>
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            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
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                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">70-15</strain>
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    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHZ1</accession>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15</strain>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720826.1">
        <property type="nucleotide sequence ID" value="XM_003720778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHZ1"/>
    <dbReference type="SMR" id="G5EHZ1"/>
    <dbReference type="FunCoup" id="G5EHZ1">
        <property type="interactions" value="124"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EHZ1"/>
    <dbReference type="GeneID" id="2682452"/>
    <dbReference type="KEGG" id="mgr:MGG_02899"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02899"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_12_1_1"/>
    <dbReference type="OMA" id="AIMCIVP"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF36">
        <property type="entry name" value="PROLINE-SPECIFIC PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="512"/>
        </location>
    </feature>
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        <location>
            <begin position="59"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EAQ71256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA46083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="560" mass="61571" checksum="CBB19362B7947A60" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI43</accession>
    <name>G5EI43_PYRO7</name>
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        <recommendedName>
            <fullName evidence="5">37S ribosomal protein Rsm22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g323</name>
        <name evidence="3" type="ORF">MGG_02604</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721192.1">
        <property type="nucleotide sequence ID" value="XM_003721144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI43"/>
    <dbReference type="STRING" id="242507.G5EI43"/>
    <dbReference type="GeneID" id="2682344"/>
    <dbReference type="KEGG" id="mgr:MGG_02604"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02604"/>
    <dbReference type="eggNOG" id="ENOG502S2HP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043442_0_0_1"/>
    <dbReference type="OMA" id="KLNALGH"/>
    <dbReference type="OrthoDB" id="66510at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028241">
        <property type="entry name" value="RAVE2/Rogdi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618">
        <property type="entry name" value="LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13618:SF1">
        <property type="entry name" value="PROTEIN ROGDI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10259">
        <property type="entry name" value="Rogdi_lz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="292"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="42639" checksum="E6B0733448365BAD" modified="2011-12-14" version="1">MSVDIYPPIAAAELKLAIQDTQRRELTWLLDDLQATLGEFRHGLEDCYALLAPIDPGSTLVVSTPRNESVKGHVTRVGTRIVKGTLSLRLRTAPPQTLSIDPTHPIHLAPLTLLHARLTDALDVLTRTLEFLPEGGGSKTTLPPAADATAAAAFVSAQLRLLSTTLHESSAILKGRPLTDTDPGWTTLSAAPGHFLAPPAPPPPTSNLNNFLSAPQQQTDASAANPLHNISIYFSLQESALVLWVRSLEPADAAPSFGMKFALAIGTARRLEHDESDVIFGYCCAGLDGKPAGGEEEHRRHGPRTSPTLSVKRPVSQSGPPVLSGTRDSTRRSSSRNPGGAAGGREKDGDAVQVYVREKIRVESADPSLMSLSAKLGALSHTLTMARRNLAAVMGEELEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI66</accession>
    <name>G5EI66_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g690</name>
        <name evidence="3" type="ORF">MGG_02926</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720791.1">
        <property type="nucleotide sequence ID" value="XM_003720743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI66"/>
    <dbReference type="GeneID" id="2682479"/>
    <dbReference type="KEGG" id="mgr:MGG_02926"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02926"/>
    <dbReference type="HOGENOM" id="CLU_1133787_0_0_1"/>
    <dbReference type="OrthoDB" id="10488347at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="245" mass="26716" checksum="F534C8C8DEC44F91" modified="2011-12-14" version="1">MASGLPCSAGRQLCVFLSCSLLSGSRPEPTARDLSSIALISASTTLFGHGAQASDGALVLPWCRLGNPGNSRDLEQQDSNHSWASLGNPQGADSHWILIPLEHILLGFLCIYMEGARLLSRSYMRTTGSSSGSMATLQVRPVTWDLDTSLGSATLDPQNKFTDHGLQSPECTPNGHLPEEAMACLEWTTQMSLFFFESEKTPMQIPWAIPAFTASLSAAIAQWYWKIRYTIRPNVETCTRVFTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2006-03-07" modified="2025-10-08" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>Q2KET0</accession>
    <accession>A4RAP6</accession>
    <name>Q2KET0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ent-kaurene oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGCH7_ch7g956</name>
        <name evidence="12" type="ORF">MGG_09156</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15</strain>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845953.1">
        <property type="nucleotide sequence ID" value="XM_016990465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q2KET0"/>
    <dbReference type="SMR" id="Q2KET0"/>
    <dbReference type="GeneID" id="2680083"/>
    <dbReference type="KEGG" id="mgr:MGG_09156"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09156"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_3_1"/>
    <dbReference type="OMA" id="FPVVNDY"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000059">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EAQ71549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KYQ30449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="494" mass="54420" checksum="3933A29E2FA71379" modified="2006-03-07" version="1">MIAELLFNPGTWTALAVLAAAYYHFFLRSPALPFPPANKSASELQDASSLITNSLSKSNGGPVVVTLGSGGRKILLPSSLAAWVKTNRDLDHQQLVREDFMSGIPGFEGNTLLHQSGSPIMDIIKTRMGLNDGTLRTLNASVKRTLHDTLGEGAEWHAIDWYAGTSNIIARAASSVFVGPEKADDPEWLELAQTYVTAYFTGVAELGTYPAWARSIVHWFLPNVKTCRKLLPRARVIIGQVAAAREKEAAAARREGRPAPEYNDALEWVRAVSGGEVDPAEAQLCLAMAAFFTTAELLRVLLIEVARHPEYVDELREEISTQISKHGLSVAGINGMVLLDSFMKESQRLNSGPVVLERVALRDTALPDGRIIPRGSHIMVDSMDLWKSEKYPDPNKFDGRRFLKKRKAGDSASQFVQSGPDYHVFGGGRHICPGRFFASQELKLIMAHLLLKYDVRLGEGCDPKVIPNGFFVMIDPTVKFEVKRRKSRDADALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4F6</accession>
    <name>A0A151V4F6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_18107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845966.1">
        <property type="nucleotide sequence ID" value="XM_016990567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4F6"/>
    <dbReference type="GeneID" id="27922191"/>
    <dbReference type="KEGG" id="mgr:MGG_18107"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18107"/>
    <dbReference type="InParanoid" id="A0A151V4F6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KYQ30462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="63" mass="6698" checksum="B02F22F562CBE933" modified="2016-06-08" version="1">MTEPSVESSEFSAVDQGSTQTDYNISNMDIIHCVGEQSPRSSVTPSLSSGMVKASVNSRNFIG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-10-19" modified="2025-06-18" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4QR60</accession>
    <accession>G4N6S6</accession>
    <name>GATA_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial</fullName>
            <shortName evidence="1">Glu-AdT subunit A</shortName>
            <ecNumber evidence="1">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ORF">MGG_13483</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="1"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716212.1">
        <property type="nucleotide sequence ID" value="XM_003716164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4QR60"/>
    <dbReference type="SMR" id="A4QR60"/>
    <dbReference type="FunCoup" id="A4QR60">
        <property type="interactions" value="337"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4QR60"/>
    <dbReference type="EnsemblFungi" id="MGG_13483T0">
        <property type="protein sequence ID" value="MGG_13483T0"/>
        <property type="gene ID" value="MGG_13483"/>
    </dbReference>
    <dbReference type="GeneID" id="5051641"/>
    <dbReference type="KEGG" id="mgr:MGG_13483"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13483"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_7_6_1"/>
    <dbReference type="InParanoid" id="A4QR60"/>
    <dbReference type="OMA" id="QPASYCG"/>
    <dbReference type="OrthoDB" id="421993at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF7">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000413354" description="Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial">
        <location>
            <begin position="1"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="517" mass="54881" checksum="80CC48912023071E" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-07-24" modified="2025-04-09" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>A4R8V2</accession>
    <accession>G4N7U1</accession>
    <name>PLPL_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Patatin-like phospholipase domain-containing protein MGG_12849</fullName>
            <ecNumber>3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ORF">MGG_12849</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable lipid hydrolase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PLPL family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717214.1">
        <property type="nucleotide sequence ID" value="XM_003717166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R8V2"/>
    <dbReference type="STRING" id="242507.A4R8V2"/>
    <dbReference type="EnsemblFungi" id="MGG_12849T0">
        <property type="protein sequence ID" value="MGG_12849T0"/>
        <property type="gene ID" value="MGG_12849"/>
    </dbReference>
    <dbReference type="GeneID" id="5050218"/>
    <dbReference type="KEGG" id="mgr:MGG_12849"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12849"/>
    <dbReference type="eggNOG" id="KOG2214">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009031_2_0_1"/>
    <dbReference type="InParanoid" id="A4R8V2"/>
    <dbReference type="OMA" id="CSWFTRG"/>
    <dbReference type="OrthoDB" id="15478at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07232">
        <property type="entry name" value="Pat_PLPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF66">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE PTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0442">Lipid degradation</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000295561" description="Patatin-like phospholipase domain-containing protein MGG_12849">
        <location>
            <begin position="1"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="375"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="745"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="3">
        <location>
            <begin position="406"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="746"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="777"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="787" mass="88461" checksum="DAD66CE20AB01316" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-07-01" modified="2025-06-18" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RMB1</accession>
    <accession>G4MU88</accession>
    <name>XPOT_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Exportin-T</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Exportin(tRNA)</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Karyopherin-beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>tRNA exportin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">LOS1</name>
        <name type="ORF">MGG_10127</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Shuttles between the nucleus and the cytoplasm.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exportin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713776.1">
        <property type="nucleotide sequence ID" value="XM_003713728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RMB1"/>
    <dbReference type="SMR" id="A4RMB1"/>
    <dbReference type="FunCoup" id="A4RMB1">
        <property type="interactions" value="1037"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RMB1"/>
    <dbReference type="EnsemblFungi" id="MGG_10127T0">
        <property type="protein sequence ID" value="MGG_10127T0"/>
        <property type="gene ID" value="MGG_10127"/>
    </dbReference>
    <dbReference type="GeneID" id="2681738"/>
    <dbReference type="KEGG" id="mgr:MGG_10127"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10127"/>
    <dbReference type="eggNOG" id="KOG2021">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004414_0_1_1"/>
    <dbReference type="InParanoid" id="A4RMB1"/>
    <dbReference type="OMA" id="HEMFLFG"/>
    <dbReference type="OrthoDB" id="26399at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071528">
        <property type="term" value="P:tRNA re-export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000355">
        <property type="entry name" value="Exportin-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045546">
        <property type="entry name" value="Exportin-T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040017">
        <property type="entry name" value="XPOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952:SF11">
        <property type="entry name" value="EXPORTIN-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952">
        <property type="entry name" value="EXPORTIN-T/LOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19282">
        <property type="entry name" value="Exportin-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_0000343097" description="Exportin-T">
        <location>
            <begin position="1"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="1027" mass="114818" checksum="0FB9095EDDF64D02" modified="2012-01-25" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKE4</accession>
    <name>G4MKE4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fungal specific transcription factor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_10529</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710145.1">
        <property type="nucleotide sequence ID" value="XM_003710097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKE4"/>
    <dbReference type="SMR" id="G4MKE4"/>
    <dbReference type="STRING" id="242507.G4MKE4"/>
    <dbReference type="GeneID" id="2682164"/>
    <dbReference type="KEGG" id="mgr:MGG_10529"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10529"/>
    <dbReference type="eggNOG" id="ENOG502RSRA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019529_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKE4"/>
    <dbReference type="OMA" id="FPCFSET"/>
    <dbReference type="OrthoDB" id="5319458at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G12570)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="626"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="644"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA57533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="790" mass="88795" checksum="0B8964F7A654EECD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLB5</accession>
    <name>G4MLB5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710257.1">
        <property type="nucleotide sequence ID" value="XM_003710209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLB5"/>
    <dbReference type="STRING" id="242507.G4MLB5"/>
    <dbReference type="GeneID" id="2676045"/>
    <dbReference type="KEGG" id="mgr:MGG_05400"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05400"/>
    <dbReference type="eggNOG" id="ENOG502SJV3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038384_0_1_1"/>
    <dbReference type="InParanoid" id="G4MLB5"/>
    <dbReference type="OMA" id="WIWAIAG"/>
    <dbReference type="OrthoDB" id="4838853at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42024">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42024:SF1">
        <property type="entry name" value="AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="301" mass="33288" checksum="644973C0E982E145" modified="2011-12-14" version="1">MAVAGYPSPEAIPEEQGQRRGRQHPQQHAAGGPPPLNFTLHGKRTGIAMFVVFTFFDSLVLPVGLYFGLWYGFGPGSPKDQPLSASVVMTIVTAIIGGASIWELLQRAWRLGRKGSRCRVSFGETDAFWMIWDAELGLISRLMAMPVSTVLLIFGTVSLALDILRYFSIPAPLRISSTRRGAQLRPGIYPLIEDICAVDGAGNTAFRESLNRRYSDSAVFRAMLQRLGVFWALGAECCAVATLALVLGLDDGLDDYAYAIGWALPWVWAAPWAGVTIFYVRRELDKERRAWALELDSYRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLU9</accession>
    <name>G4MLU9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710340.1">
        <property type="nucleotide sequence ID" value="XM_003710292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLU9"/>
    <dbReference type="GeneID" id="12986288"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16371"/>
    <dbReference type="eggNOG" id="ENOG502SYTK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122022_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLU9"/>
    <dbReference type="OrthoDB" id="5241776at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="206" mass="22542" checksum="D622BF725D662D11" modified="2011-12-14" version="1">MAACSACESRGIPKCAVSPQDSSRCVECLRSNRSGCDVLEISPAQFRKIGQQHAKLEEELEAAEEARRRADEKVRLADAKVERLRKQKKMWFEKMMRAVSRGIDDLEELDRVEREEAEQEERRRSAEVLPEVSLESLLPDSNFLWDSTFPMGPLNPSLLDEMNVLAQHSVGSSGGMVSSPGRSLTSGNDPTPDSTGGAVPGNPGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMK6</accession>
    <name>G4MMK6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003709548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMK6"/>
    <dbReference type="GeneID" id="5049595"/>
    <dbReference type="KEGG" id="mgr:MGG_11809"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11809"/>
    <dbReference type="eggNOG" id="ENOG502SMK2">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="InterPro" id="IPR021822">
        <property type="entry name" value="DUF3405"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36205">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="DUF3405"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="52"/>
            <end position="72"/>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
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        <location>
            <begin position="696"/>
            <end position="716"/>
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    </feature>
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        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
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            <begin position="12"/>
            <end position="26"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="740" mass="84473" checksum="3DED970FD029E96C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
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    </protein>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709597.1">
        <property type="nucleotide sequence ID" value="XM_003709549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMK7"/>
    <dbReference type="STRING" id="242507.G4MMK7"/>
    <dbReference type="GeneID" id="2685044"/>
    <dbReference type="KEGG" id="mgr:MGG_06871"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06871"/>
    <dbReference type="eggNOG" id="ENOG502S8AT">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="4034134at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Put_GTT3"/>
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        <property type="entry name" value="GLUTATHIONE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GLUTATHIONE TRANSFERASE 3"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="343" mass="37562" checksum="F510C0D3DA763917" modified="2011-12-14" version="1">MSGSNAWLRAQRKSELIGIAEHIGLKNYDGLKKDLELTLDEHLAANSDRYSSDPKLAPYFQSRNRTIGSPIKKDVPEFKIPKRRMGSKTDSEIIAATAVDDEPSIASTTSALVHTPARAFSIAQRIPLPATPAEVAEAVDRSTAVVRQHVNSVLAESSIPEYTQATRQSLSTVTAVLLTAHLFELYFLRQELLADRYAFTIPAIKALGTRDYIINMPDLFLLLTSSFWKPASIWMLTSFIIPSFFGYFFNLSAANSHSPGVATRGRPRGVTHDVEYRVDPLTYSVVKAVISYVVYAQGAALGGYVDPNSVARINSALYGGWKGVLVGSGITGLMAMYDAVLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNA4</accession>
    <name>G4MNA4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708839.1">
        <property type="nucleotide sequence ID" value="XM_003708791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNA4"/>
    <dbReference type="GeneID" id="2681228"/>
    <dbReference type="KEGG" id="mgr:MGG_02073"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02073"/>
    <dbReference type="HOGENOM" id="CLU_1652504_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNA4"/>
    <dbReference type="OrthoDB" id="5238002at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465414" evidence="2">
        <location>
            <begin position="21"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="160" mass="17049" checksum="A1A5A3025B5EEF64" modified="2011-12-14" version="1">MQFSVLHIFTLLALSTSVLGVPTSQHGNSVAQAGSGNAQPIAGAGASAPSPHDSGEACVPCKEGDKAEGGAGGPNKLSTWRKIRNNSRYHVLDKVFFMRYNTDKPKDKAYWDWREDKVKGKSWDGVAMRNHPVYTTHGQTFLCCGGGISMVGGAPVEKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP60</accession>
    <name>G4MP60_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708931.1">
        <property type="nucleotide sequence ID" value="XM_003708883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP60"/>
    <dbReference type="SMR" id="G4MP60"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="GeneID" id="2681070"/>
    <dbReference type="KEGG" id="mgr:MGG_02159"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02159"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_4_1_1"/>
    <dbReference type="InParanoid" id="G4MP60"/>
    <dbReference type="OMA" id="TWWSEVE"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015:SF22">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="2">
        <location>
            <begin position="337"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="458" mass="49323" checksum="6E8053BF9004C0C7" modified="2011-12-14" version="1">MTAANEKPLVVAMSLPGAGHTIPVMRAAAHLASRGFDVWFVTAADFESSALSSGIARFFPSPSPFALHPDLMAGYMDLPEGPARLDFVFRNVFLRDTKQYADALRGALETARTETPGRRVVVLQDMFAGGALPFIHGAPPPKGYEDDGFPPVVSLNVSVLFCTSADAPPIGFPVDPVGREGEEVLRLHGEFNAGTAETRAMLNGILGEMGCTRRVEALADAWLEGPDLTLQLCSPGLEYRRRDLSPKIRFVGGLPLPEGKGGPLPDWLREHVEAQRESHANGQAKKRKLVFVTQGTVDIDHSELLIPALQGLGAREDLFVVGVLGRKGARLPESVESSLPSANVKVLDYFSYNDILPHADVFVTNGGYGGFMHGVMNGSPMIIAGVSNDKGDVANRMENAGLGINLRTATPTPEQISAAVDQVLADSSYKQRALEIKKENEEMDSFARIEKAVLEVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPE9</accession>
    <name>G4MPE9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7 11">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_11771</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 10 11">Belongs to the peptidase C12 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7 11"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709814.1">
        <property type="nucleotide sequence ID" value="XM_003709766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPE9"/>
    <dbReference type="SMR" id="G4MPE9"/>
    <dbReference type="STRING" id="242507.G4MPE9"/>
    <dbReference type="MEROPS" id="C12.009"/>
    <dbReference type="GeneID" id="5049559"/>
    <dbReference type="KEGG" id="mgr:MGG_11771"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11771"/>
    <dbReference type="eggNOG" id="KOG2778">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018316_1_0_1"/>
    <dbReference type="InParanoid" id="G4MPE9"/>
    <dbReference type="OMA" id="YIQYEIQ"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09617">
        <property type="entry name" value="Peptidase_C12_UCH37_BAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000009">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017390">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041507">
        <property type="entry name" value="UCH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18031">
        <property type="entry name" value="UCH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038120">
        <property type="entry name" value="Ubiquitinyl_hydrolase_UCH37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 10" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="13">
        <location>
            <begin position="4"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 10">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 10">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="9 10">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR038120-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038120-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA57202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="328" mass="36412" checksum="BDC570DA6D3DBF3E" modified="2011-12-14" version="1">MSGGWNTIESDAGVFTYLLEELGVKGVQFEELLTLEPESLASLHPVYGVIFLFKYPTDQPYRAEKPLDGDFDHDAADDGSLFFASQTIQNACGTQALLSVLLNRTADVEVGPALSDFREFTMPLPAEFRGEALSNSDLIRSVHNSFARSSPFADETSRPADADSEDAFHFIAYTAAGGRLWELDGLQPAPISHGPCDSTDGEDFANKVMAVLQRRMQRYESSEIRFNLLAMCRDLRLRAAELGDVEAAERERRKRREWRFENGLRRHNFVGFAGEVLRGVVAAKVNEGGGEAYDKWVEQAKQKMMKRIGDRSERKRSAAGGGDVEMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPR4</accession>
    <name>G4MPR4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709823.1">
        <property type="nucleotide sequence ID" value="XM_003709775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPR4"/>
    <dbReference type="GeneID" id="12985265"/>
    <dbReference type="KEGG" id="mgr:MGG_16244"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16244"/>
    <dbReference type="HOGENOM" id="CLU_2831653_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPR4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="66" mass="7341" checksum="7F63BD08AD6E4439" modified="2011-12-14" version="1">MQAVRGVIWGIVSVVVASSIGNAYCAAAVLVRRSTRKNEVRYTWVGYHGRGEFATKLHCTPEFEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ62</accession>
    <name>G4MQ62_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HhH-GPD family base excision DNA repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709067.1">
        <property type="nucleotide sequence ID" value="XM_003709019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQ62"/>
    <dbReference type="SMR" id="G4MQ62"/>
    <dbReference type="GeneID" id="2681399"/>
    <dbReference type="KEGG" id="mgr:MGG_02302"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02302"/>
    <dbReference type="eggNOG" id="ENOG502QRUG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_9_1_1"/>
    <dbReference type="InParanoid" id="G4MQ62"/>
    <dbReference type="OMA" id="LHVLMVG"/>
    <dbReference type="OrthoDB" id="5607at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000702">
        <property type="term" value="F:oxidized base lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47203">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47203:SF1">
        <property type="entry name" value="HYPOTHETICAL BASE EXCISION DNA REPAIR PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="2">
        <location>
            <begin position="176"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="382" mass="41268" checksum="1690C2D3F76CF03E" modified="2011-12-14" version="1">MIRGRVLMARVTRSTAAKAKAGLDTPIKTEQPTQPTGRKRVASKTATDQPNGSRKKAKVEAVKTESAAAKLERLDDDHDVLSKIPTAPIASTSPSTSSTLASRKLKQYYGGDASKLGPFPNFPHPTPAECKRAHRILAKLHGARKRPTVPLTAGPAGRAGCGDAPSVLDALVRTILSQNTSDSNSARAKRSMDRAYGGRHDNWPAVVAGGVGKLEEAIRCGGLSVVKSRVIMSILETCAQRYGSYSLDHLREASDEEAMREMLAFKGVGPKTASCVLLFCLGRESFAVDTHVHRLTGMLGWRPAGTSREEAHLHLDARIPDEDKYGLHVLLITHGKRCAECKAGGKSSGKCELRRALREKDEGFKEEDTDSEEKPAKVEEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQD4</accession>
    <name>G4MQD4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytosolic Fe-S cluster assembly factor CFD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_10636</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710732.1">
        <property type="nucleotide sequence ID" value="XM_003710684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQD4"/>
    <dbReference type="SMR" id="G4MQD4"/>
    <dbReference type="FunCoup" id="G4MQD4">
        <property type="interactions" value="148"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MQD4"/>
    <dbReference type="GeneID" id="2682248"/>
    <dbReference type="KEGG" id="mgr:MGG_10636"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10636"/>
    <dbReference type="eggNOG" id="KOG3022">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024839_0_1_1"/>
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        <property type="component" value="Chromosome 1"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="C:cytosolic [4Fe-4S] assembly scaffold complex"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001300">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor CFD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028600">
        <property type="entry name" value="NUBP2/Cfd1_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF19">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="28"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA58120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="309" mass="32836" checksum="F0FFC3F470751F21" modified="2011-12-14" version="1">MRERRLTDVPTRRGAIRSSRSDSGVLSGKGGVGKSSVTTQLALSLSLAGHSVGVLDVDLTGPNIPRMFSVEDAKVTQAPGGWLPVPVHESNPASNTGSLRVMSLGFLLRDRGDAVVWRGPKKTAMVRQFLSDVLWGDLDFLLVDTPPGTSDEHISLAETLLQKTVPGQLAGAVVVTTPQAVATADVRKELNFCKKTAIPVLGVIENMSGYICPCCGEKTNIFMSGGGEVMANDFGVKFLGRIPIDPVFVELIETGRRPRYQAPAKPDPEAASESEARDPGLLVEKYTDSILAPIFGNIAAELIRGVSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQK1</accession>
    <name>G4MQK1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709103.1">
        <property type="nucleotide sequence ID" value="XM_003709055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQK1"/>
    <dbReference type="GeneID" id="12984354"/>
    <dbReference type="KEGG" id="mgr:MGG_16101"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16101"/>
    <dbReference type="HOGENOM" id="CLU_2671534_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQK1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="75" mass="8075" checksum="38094772798D3E98" modified="2011-12-14" version="1">MPPALEQILILSVTKHSPLLWWLGKLGEGYADKFGGKGGIFTATTIPVPSIGVDQCNSAARTRIPDTIMHVRNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQL7</accession>
    <name>G4MQL7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyrroline-5-carboxylate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_02349</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709119.1">
        <property type="nucleotide sequence ID" value="XM_003709071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQL7"/>
    <dbReference type="SMR" id="G4MQL7"/>
    <dbReference type="STRING" id="242507.G4MQL7"/>
    <dbReference type="GeneID" id="2681446"/>
    <dbReference type="KEGG" id="mgr:MGG_02349"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02349"/>
    <dbReference type="eggNOG" id="KOG3124">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042344_0_1_1"/>
    <dbReference type="InParanoid" id="G4MQL7"/>
    <dbReference type="OMA" id="ILFICTR"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="5">
        <location>
            <begin position="7"/>
            <end position="104"/>
        </location>
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    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="6">
        <location>
            <begin position="187"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA56507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="299" mass="31459" checksum="D86E898C5C825144" modified="2011-12-14" version="1">MSAPDRLTFIGGGHLAQAVLSGIYSSGTAWKDSCAVAVTARRPEHAAQLRRRYPLALATTDNLHPRIWAADDRGADPDHHHHHVVFICTRPAEVPQVCREIAGALAALRAAARPTVVTMCPGVSVAQLLSWLPRGTPVVRSMPNLPVTRRQGATALFPSADAVGGSVELVAAVLGLVSPAVSVLPEESLLDVAASVSGSAPAYFYYLIESLVSAAEARGMSAETARSLVVQSCLGSGVLARDSDKPVRVLREEVCVPGGSTEKAVAHLMDKGLPDIVLGAVDRSLKANREMGCVRDEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQQ6</accession>
    <name>G4MQQ6_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09305</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003709907.1"/>
    </dbReference>
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    <dbReference type="STRING" id="242507.G4MQQ6"/>
    <dbReference type="GeneID" id="2680220"/>
    <dbReference type="KEGG" id="mgr:MGG_09305"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09305"/>
    <dbReference type="eggNOG" id="ENOG502SPEQ">
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="523" mass="59079" checksum="8D1035DC25432B9D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS92</accession>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">MGG_04493</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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            <taxon>Pyricularia</taxon>
        </lineage>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710962.1">
        <property type="nucleotide sequence ID" value="XM_003710914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS92"/>
    <dbReference type="GeneID" id="2678004"/>
    <dbReference type="KEGG" id="mgr:MGG_04493"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04493"/>
    <dbReference type="eggNOG" id="ENOG502SUJA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031212_0_0_1"/>
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    <dbReference type="OMA" id="IDDGFKH"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <dbReference type="InterPro" id="IPR057082">
        <property type="entry name" value="PH_C"/>
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    <dbReference type="InterPro" id="IPR057081">
        <property type="entry name" value="PH_N"/>
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        <property type="entry name" value="PH_FT_C"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PH_FT_N"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
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        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
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            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA58350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="597" mass="68058" checksum="1D8EE57DA4653180" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSG8</accession>
    <name>G4MSG8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">beta-glucosidase</fullName>
            <ecNumber evidence="10">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_11210</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="10"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714391.1">
        <property type="nucleotide sequence ID" value="XM_003714343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSG8"/>
    <dbReference type="SMR" id="G4MSG8"/>
    <dbReference type="STRING" id="242507.G4MSG8"/>
    <dbReference type="GeneID" id="2679193"/>
    <dbReference type="KEGG" id="mgr:MGG_11210"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11210"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_2_0_1"/>
    <dbReference type="InParanoid" id="G4MSG8"/>
    <dbReference type="OMA" id="PAPYGGW"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="UniPathway" id="UPA00696"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000003">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF2">
        <property type="entry name" value="BETA-GLUCOSIDASE F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466089" description="beta-glucosidase" evidence="11">
        <location>
            <begin position="22"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="12">
        <location>
            <begin position="780"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA54584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="876" mass="94894" checksum="0F95FC0AC8CEBFCC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSH1</accession>
    <name>G4MSH1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prp 4 CRoW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714394.1">
        <property type="nucleotide sequence ID" value="XM_003714346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSH1"/>
    <dbReference type="GeneID" id="2679196"/>
    <dbReference type="KEGG" id="mgr:MGG_01444"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01444"/>
    <dbReference type="eggNOG" id="ENOG502RZBP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085827_1_1_1"/>
    <dbReference type="InParanoid" id="G4MSH1"/>
    <dbReference type="OMA" id="DPKECAK"/>
    <dbReference type="OrthoDB" id="5409186at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465361" description="Prp 4 CRoW domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="21472" checksum="72F851DBF6F16D14" modified="2011-12-14" version="1">MRFNSITAAACLVVATSALNSSPEAIFGYSNIEARADNNTVYVPTQTLCGMGDTCAQACGASFDMCPSNDESIHCFDKQNQKCCPGGKGVSCDAGFFCAANAKGEQICCPEGKPLDQCAGAVSSLAPVPLSTAAPTTSAAVTKNVTIATTGAVVKSTALPSGTAQATGVVPTKSVSGGSGSGPAPTSDSSPSPIPVGGAASAVAPAGMVVLAFAGLAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSH7</accession>
    <name>G4MSH7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714399.1">
        <property type="nucleotide sequence ID" value="XM_003714351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSH7"/>
    <dbReference type="SMR" id="G4MSH7"/>
    <dbReference type="STRING" id="242507.G4MSH7"/>
    <dbReference type="GeneID" id="2679199"/>
    <dbReference type="KEGG" id="mgr:MGG_01447"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01447"/>
    <dbReference type="eggNOG" id="ENOG502S2DU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021934_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSH7"/>
    <dbReference type="OMA" id="YGFHASI"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF108">
        <property type="entry name" value="DAGKC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAGKc" evidence="2">
        <location>
            <begin position="219"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="591" mass="64402" checksum="2143F8D6DEDCDFB3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTE8</accession>
    <name>G4MTE8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_14791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714506.1">
        <property type="nucleotide sequence ID" value="XM_003714458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTE8"/>
    <dbReference type="GeneID" id="5050152"/>
    <dbReference type="KEGG" id="mgr:MGG_14791"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14791"/>
    <dbReference type="eggNOG" id="ENOG502SVX1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039749_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTE8"/>
    <dbReference type="OMA" id="QHVENYY"/>
    <dbReference type="OrthoDB" id="5421765at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="396" mass="41843" checksum="81BAD120B2F377F4" modified="2011-12-14" version="1">MELVPRSPQETAIVTVTPSAVITVTSSPPTGTTVVTTVTPAISSAPHNPSDAASAPPAALGSDGGGLGSGAVAGVAIGCIIAGIAIGAIAAIWFLRRRQRGVGPEETQYMLSNTAGGVYDPKDPMGAAMAADPFRLDQILAPPLPDEVISAELQNLSRIIQQHVMENYHRELVPVDQNALHRALHDLGLGNDSAIPSGQLVILAVSPQGRATALQHIIARAATASVVLSSTARHSLLPLSMSAFMREVAPTERDRGSAKAVSAAFARWRQISTFLINPNRSDRIPLQPTEAMTGQKARELVAALNVLLGPFVDHNLVEPDVQQGQLYDVVMRVAQFGYMLISQPGEFRLRWDAGPPMTAGSDVVVVCPGLDKISDEHGNRYSPSRTLLAPVAEIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTF4</accession>
    <name>G4MTF4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_01539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714512.1">
        <property type="nucleotide sequence ID" value="XM_003714464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTF4"/>
    <dbReference type="GeneID" id="2679397"/>
    <dbReference type="KEGG" id="mgr:MGG_01539"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01539"/>
    <dbReference type="eggNOG" id="ENOG502RACA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_201328_1_0_1"/>
    <dbReference type="InParanoid" id="G4MTF4"/>
    <dbReference type="OrthoDB" id="5210410at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="70" mass="7381" checksum="11834F59FF0CD31D" modified="2011-12-14" version="1">MDHQAKSSLSRGQAPSIIRNRRVVAVAASAAAVGMVIKLRADAIKKNEMAQKNSAVPNFYVSVERSGGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTQ4</accession>
    <name>G4MTQ4_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
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        <name evidence="2" type="ORF">MGG_04739</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003713652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTQ4"/>
    <dbReference type="GeneID" id="2678062"/>
    <dbReference type="KEGG" id="mgr:MGG_04739"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04739"/>
    <dbReference type="eggNOG" id="ENOG502R3N6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007899_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTQ4"/>
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    <dbReference type="OrthoDB" id="3199516at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="786"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="789"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="914" mass="100630" checksum="D27A6D0069518657" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTW6</accession>
    <name>G4MTW6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">14-3-3 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_01588</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 14-3-3 family.</text>
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        <property type="protein sequence ID" value="EHA54760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714567.1">
        <property type="nucleotide sequence ID" value="XM_003714519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTW6"/>
    <dbReference type="SMR" id="G4MTW6"/>
    <dbReference type="FunCoup" id="G4MTW6">
        <property type="interactions" value="1380"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTW6"/>
    <dbReference type="GeneID" id="2679302"/>
    <dbReference type="KEGG" id="mgr:MGG_01588"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01588"/>
    <dbReference type="eggNOG" id="KOG0841">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058290_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTW6"/>
    <dbReference type="OMA" id="KGCQLAR"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="CDD" id="cd11309">
        <property type="entry name" value="14-3-3_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="5">
        <location>
            <begin position="3"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="234"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA54760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="272" mass="30094" checksum="511A59F117C15F2B" modified="2011-12-14" version="1">MGHEDAVYLAKLAEQAERYEEMVENMKIVASEDRDLTVEERNLLSVAYKNVIGARRASWRIVTSIEQKEESKGNSSQVGLIKEYRTKIEAELAKICEDILSVLDKHLIPSAKSGESKVFYHKMKGDYHRYLAEFAIGDKRKDSADKSLEAYKAATEVAQTELPPTHPIRLGLALNFSVFYYEILNAPDQACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSSEAEPTASTGHAEAPAAAAATEEKPAEAAAAAEEAPKPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU58</accession>
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        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
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    <gene>
        <name evidence="6" type="ORF">MGG_04816</name>
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    <organism evidence="6 7">
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713746.1">
        <property type="nucleotide sequence ID" value="XM_003713698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU58"/>
    <dbReference type="SMR" id="G4MU58"/>
    <dbReference type="STRING" id="242507.G4MU58"/>
    <dbReference type="GeneID" id="2677748"/>
    <dbReference type="KEGG" id="mgr:MGG_04816"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04816"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_012062_28_1_1"/>
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    <dbReference type="OMA" id="GVPNMYQ"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000684">
        <property type="entry name" value="Putative glycine-rich RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="57"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="236" mass="26109" checksum="52F9177BEA2C7A21" modified="2011-12-14" version="1">MRARYYGPEKNTRLHICSPSLLERIKSRNQVSLRDETRPLPTPLFFLFSLSFSGIMSKLFIGGLAWHTEEGTLRQKFEEYGVVEEAVVVKDRDTGRSRGFGFVRYTNEDDAQKAITAMNNVEFDGRTIRVDKASDTGPRGGGGGFRGGYGGRGGYASPQMHPMPYGMHPQQQYGAPQMYPQPYGRGGYPQQMPGYGAPPAQTWQAAAGHPGYYPDPSGQIPPQQQMPPQNPQGGPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUC1</accession>
    <name>G4MUC1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714615.1">
        <property type="nucleotide sequence ID" value="XM_003714567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUC1"/>
    <dbReference type="GeneID" id="12984699"/>
    <dbReference type="KEGG" id="mgr:MGG_15744"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15744"/>
    <dbReference type="HOGENOM" id="CLU_2278016_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUC1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="102" mass="10969" checksum="77C7E149D8DA7288" modified="2011-12-14" version="1">MATRQQQRMVVRRAESCTAERELRGGVSGTLPTVAYNSGSDGHQSFFAVTCTVRPAASRAGSSTSPIVMTISGTTLYCIVICCLVEETNYARAACITKWVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV10</accession>
    <name>G4MV10_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07319</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715551.1">
        <property type="nucleotide sequence ID" value="XM_003715503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV10"/>
    <dbReference type="SMR" id="G4MV10"/>
    <dbReference type="STRING" id="242507.G4MV10"/>
    <dbReference type="GeneID" id="2683215"/>
    <dbReference type="KEGG" id="mgr:MGG_07319"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07319"/>
    <dbReference type="eggNOG" id="KOG1601">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029475_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV10"/>
    <dbReference type="OMA" id="HYATRAH"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172:SF24">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172">
        <property type="entry name" value="OS01G0976800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="450"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="236"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="500" mass="54247" checksum="9C2C5BCB121548DE" modified="2011-12-14" version="1">MEAGDSVPRQSAHLSASNNHSDYYSQRSREPLNRPPLRQTSSTMATAALISPSNHYSHHSPYASAYTSHPNSASSAHPPPPPPTMVSPADSARRSDDNETPHRQSLPSIRDIIGKSSDGPPGANSLPSPFSTHSSAPPPPPPRSYNDQPQTREKPPSPRQPERTATYSRPEPLPPFQDSSRGPPPRPGVPSLSIFAGGNPPKPNLPEISERRHHPGPPPPPPAMESQSAGQYAHHAPPPAHGPPQAPPPPPSSHSHMPPPLSAPTPPYSSGSAPLPPGQLPLSAYPISPRNPAPSMTSPYNTQRPPMGPEEAEYAARNQLKYNGPPGRPYESWSFAESLAKVGGSAHVLLSFADRYAQIAQDEPVPSRMPSDAEISDMVANCEHVMIALDALRNQRMYLSNELHREGAPRPSRGYGGEDEDVNMYNDGMKQSYNVMETKKRRGRAAPPGRCHSCNRMDTPEWRRGPDGARTLCNACGLHYAKLERKKQMERGQARKDAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV41</accession>
    <name>G4MV41_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal peptidase complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_11330</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Dispensable for SPC enzymatic activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPCS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713863.1">
        <property type="nucleotide sequence ID" value="XM_003713815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV41"/>
    <dbReference type="SMR" id="G4MV41"/>
    <dbReference type="STRING" id="242507.G4MV41"/>
    <dbReference type="GeneID" id="5051292"/>
    <dbReference type="KEGG" id="mgr:MGG_11330"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11330"/>
    <dbReference type="eggNOG" id="KOG4112">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134505_2_0_1"/>
    <dbReference type="InParanoid" id="G4MV41"/>
    <dbReference type="OMA" id="IHLTLWT"/>
    <dbReference type="OrthoDB" id="263893at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009542">
        <property type="entry name" value="Spc1/SPCS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06645">
        <property type="entry name" value="SPC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="106" mass="11663" checksum="E738D6D81761B913" modified="2011-12-14" version="1">MAEQLLEQARDIFEGQIDFQGQKLADNLATILLSIVGTLSFIIGYLLQDIKLAVYIGLGGTALTFALVLPPWPFFNRHPVKWLPVGGGSKPLQTSQNIVIDEKALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVB4</accession>
    <name>G4MVB4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_01746</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714743.1">
        <property type="nucleotide sequence ID" value="XM_003714695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVB4"/>
    <dbReference type="STRING" id="242507.G4MVB4"/>
    <dbReference type="GeneID" id="2679184"/>
    <dbReference type="KEGG" id="mgr:MGG_01746"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01746"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_9_0_1"/>
    <dbReference type="InParanoid" id="G4MVB4"/>
    <dbReference type="OMA" id="MHGKDVN"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001113">
        <property type="entry name" value="RNP domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="47"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="235"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="120"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="325"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="349"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="379" mass="40151" checksum="9521F7118AF8ACE0" modified="2011-12-14" version="1">MSAPVENVPTTDAAVTDVAATLADTSISGKADTKANDDNHASAVEGRRLYIGNLAYATSEGKLTEFFKGYLVERISIPKNPRTDRPVGYAFVDLSTPNEAERAIAELSGQEVLERKVSVQLARKPEPTQPKEEGANGEGAEGTRRSRSTRGRGRSGRGRGGAGRAGRSDENQGQEGATDAQAAGTTDAEVKPLTDITNKNQTDKDEKAKKEPRAPREPRERRERGPPADGIASKTKVMVANLPYDMTEARLKEVFAAYEPVSAKIALRPIPRFMIKKLQARNEPRKGRGFGFVTLASEELQQKAVTEMNGKQIDSREIAVKVAIDSPDKTDDDVAQEGEASTEANGTETAAPAVEAASAAATDAAAAPAAAPAAPATTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVV0</accession>
    <name>G4MVV0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715625.1">
        <property type="nucleotide sequence ID" value="XM_003715577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVV0"/>
    <dbReference type="SMR" id="G4MVV0"/>
    <dbReference type="GeneID" id="12986723"/>
    <dbReference type="KEGG" id="mgr:MGG_15918"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15918"/>
    <dbReference type="HOGENOM" id="CLU_2306661_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVV0"/>
    <dbReference type="OrthoDB" id="10537399at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="100" mass="11055" checksum="6D8A35E98DBC650F" modified="2011-12-14" version="1">MSSQSSKNNTPSTPATSSKAAQKAPARPKDDSDSEDEEDQLRRQVARTNQELHEQTLRATQLQEELQALRASANVNVAYPLFGTPPVRHPENLTTKCLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW53</accession>
    <name>G4MW53_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Haloacid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714822.1">
        <property type="nucleotide sequence ID" value="XM_003714774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW53"/>
    <dbReference type="STRING" id="242507.G4MW53"/>
    <dbReference type="GeneID" id="2679388"/>
    <dbReference type="KEGG" id="mgr:MGG_01809"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01809"/>
    <dbReference type="eggNOG" id="ENOG502S19E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_3_0_1"/>
    <dbReference type="InParanoid" id="G4MW53"/>
    <dbReference type="OMA" id="VLAWHRS"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019120">
        <property type="term" value="F:hydrolase activity, acting on acid halide bonds, in C-halide compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006328">
        <property type="entry name" value="2-HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01428">
        <property type="entry name" value="HAD_type_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF3">
        <property type="entry name" value="HALOACID DEHALOGENASE, TYPE II (AFU_ORTHOLOGUE AFUA_2G07750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="276" mass="30213" checksum="23E65CBDD4C8BFB2" modified="2011-12-14" version="1">MSEGHALPRASTPSSLHKIKALTFDVFGTTVNWRASIESALTSALDAKMNSAGFATLPAELQARARNLQTGGVRDSIDIIAASAWPSSFPTPDLLPDWPCAFAAAWRRSYGRFTRGFEPGITPWKDIDTHHRESLERLLEERGLAGLFTDDEVLELSRAWHRLEPWPDTRQGLARLASRGLVTAALSNGNQSLLQDLNTYHDGLGFDRLFSAEDFGAYKPNPRTYLGAVEGLGLRPDEVAMVAAHLGDLKGAKACGLRTVYLERVRRALRGCPAMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW58</accession>
    <name>G4MW58_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA replication checkpoint mediator MRC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_01813</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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</entry>
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            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Mitchell T.K."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    </reference>
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        <text evidence="9">Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.</text>
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        <text evidence="2 9">Belongs to the glycosyl hydrolase 72 family.</text>
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        <property type="entry name" value="1,3-BETA-GLUCANOSYLTRANSFERASE GAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03198">
        <property type="entry name" value="Glyco_hydro_72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07983">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="9 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005132196" description="1,3-beta-glucanosyltransferase" evidence="9">
        <location>
            <begin position="22"/>
            <end position="533"/>
        </location>
    </feature>
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        <location>
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            <end position="532"/>
        </location>
    </feature>
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        <location>
            <begin position="383"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA55883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="533" mass="55871" checksum="8C0DD7ACC361DBCA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWX0</accession>
    <name>G4MWX0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Synaptojanin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714069.1">
        <property type="nucleotide sequence ID" value="XM_003714021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWX0"/>
    <dbReference type="SMR" id="G4MWX0"/>
    <dbReference type="FunCoup" id="G4MWX0">
        <property type="interactions" value="1357"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MWX0"/>
    <dbReference type="GeneID" id="5051248"/>
    <dbReference type="KEGG" id="mgr:MGG_11279"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11279"/>
    <dbReference type="eggNOG" id="KOG1889">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003016_7_4_1"/>
    <dbReference type="InParanoid" id="G4MWX0"/>
    <dbReference type="OMA" id="ITKAQPV"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072517">
        <property type="term" value="C:host cell viral assembly compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052629">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004438">
        <property type="term" value="F:phosphatidylinositol-3-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="623"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="2">
        <location>
            <begin position="118"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="704" mass="79563" checksum="98EA9F47E86769E7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXC3</accession>
    <name>G4MXC3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Very long-chain fatty acid transport protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Very-long-chain acyl-CoA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">MGG_08257</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15</strain>
            <strain evidence="23">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Acyl-CoA synthetase required for both the import of long chain fatty acids (LCFAs) (C14-C18) and the activation very long chain fatty acids (VLCFAs) (C20-C26) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. The transport and fatty acyl-CoA synthetase activities are genetically separable and are thus independent activities. Esterifies VLCFAs in the peroxisome matrix. The VLCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54536"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58950"/>
            <dbReference type="ChEBI" id="CHEBI:138261"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Lipid droplet</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715828.1">
        <property type="nucleotide sequence ID" value="XM_003715780.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715829.1">
        <property type="nucleotide sequence ID" value="XM_003715781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXC3"/>
    <dbReference type="SMR" id="G4MXC3"/>
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        <property type="interactions" value="129"/>
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    <dbReference type="STRING" id="242507.G4MXC3"/>
    <dbReference type="GeneID" id="2678601"/>
    <dbReference type="KEGG" id="mgr:MGG_08257"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08257"/>
    <dbReference type="eggNOG" id="KOG1179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_46_3_1"/>
    <dbReference type="OMA" id="VWRQFLD"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="C:peroxisomal membrane"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000002">
        <property type="entry name" value="Long-chain fatty acid transport protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000019">
        <property type="entry name" value="Long-chain fatty acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
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    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
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    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="13" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="20">
        <location>
            <begin position="64"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="21">
        <location>
            <begin position="508"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00068795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00078285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EHA56022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="635" mass="70319" checksum="B25A45052954E914" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXK2</accession>
    <name>G4MXK2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD repeat-containing protein slp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_01236</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714140.1">
        <property type="nucleotide sequence ID" value="XM_003714092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXK2"/>
    <dbReference type="SMR" id="G4MXK2"/>
    <dbReference type="FunCoup" id="G4MXK2">
        <property type="interactions" value="137"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MXK2"/>
    <dbReference type="GeneID" id="2679415"/>
    <dbReference type="KEGG" id="mgr:MGG_01236"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01236"/>
    <dbReference type="eggNOG" id="KOG0305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014831_6_0_1"/>
    <dbReference type="InParanoid" id="G4MXK2"/>
    <dbReference type="OMA" id="PVKSHHG"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000098">
        <property type="entry name" value="WD repeat-containing protein slp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
        <property type="entry name" value="FI02843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="9">
        <location>
            <begin position="274"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="319"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="402"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="533"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="105"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="152"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="593" mass="63681" checksum="8F815A083A095E20" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYB3</accession>
    <name>G4MYB3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Exosome component 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_08100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715055.1">
        <property type="nucleotide sequence ID" value="XM_003715007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYB3"/>
    <dbReference type="SMR" id="G4MYB3"/>
    <dbReference type="FunCoup" id="G4MYB3">
        <property type="interactions" value="1060"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYB3"/>
    <dbReference type="GeneID" id="2678345"/>
    <dbReference type="KEGG" id="mgr:MGG_08100"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08100"/>
    <dbReference type="eggNOG" id="KOG3013">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034114_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYB3"/>
    <dbReference type="OMA" id="GVNGFIW"/>
    <dbReference type="OrthoDB" id="1650at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071034">
        <property type="term" value="P:CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05789">
        <property type="entry name" value="S1_Rrp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000038">
        <property type="entry name" value="Exosome complex component RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025721">
        <property type="entry name" value="Exosome_cplx_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048565">
        <property type="entry name" value="S1_RRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF4">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14382">
        <property type="entry name" value="ECR1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21266">
        <property type="entry name" value="S1_RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exosome complex component N-terminal" evidence="8">
        <location>
            <begin position="46"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="RRP4 S1" evidence="9">
        <location>
            <begin position="97"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="361" mass="38387" checksum="F0A66631A46DECEF" modified="2011-12-14" version="1">MPITISAPRAATRSQRIPSSRMDDSDSDSDSDAGAQLAMAGGEGDIVTPGQVITEDPQWMRGHGTYTFPASPAIMSSVAGTVSRTNKLLSVRPMRARYTPEVGDLVVGRIVEVQARRWKVDVGGVQLAALPLSAINLPGGILRKRTETDELQIRSFFAEGDLLVAEVQQLFGDGGASLHTRSLRYGKLRNGVFAAVSGTGGGGVVRARRQVWTMEIASTGTSATWQDKQQKAASSQAPPSIDVVLGVNGYVWISKHVEDPTEGDGSANATGTGISNMEEAVSAKMYSSQNAPIDPVTMREIVRVRGVITALVENGVRVDEDMVERAYREAVEMARASEGGEDDIYLGGERGAQLAAVLTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ10</accession>
    <name>G4MZ10_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ilp is an apoptosis inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714284.1">
        <property type="nucleotide sequence ID" value="XM_003714236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ10"/>
    <dbReference type="STRING" id="242507.G4MZ10"/>
    <dbReference type="GeneID" id="2679728"/>
    <dbReference type="KEGG" id="mgr:MGG_01355"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01355"/>
    <dbReference type="eggNOG" id="ENOG502S2F8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079969_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ10"/>
    <dbReference type="OMA" id="FEWYPHY"/>
    <dbReference type="OrthoDB" id="5335812at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053267">
        <property type="entry name" value="Verrucosidin_biosynth-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42087">
        <property type="entry name" value="ILP IS AN APOPTOSIS INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42087:SF1">
        <property type="entry name" value="ILP IS AN APOPTOSIS INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="31804" checksum="200A97ABD5825967" modified="2011-12-14" version="1">MDFSHNGGESSSFAHAQPSPEAHFDFFEWHGHFQSCVRYFLDHAQHSEHVKVVAAFINITLPFQNVNKPIMSSRSGISPTGQQQFPGKPGPGIGSSRGEVDFSFGGFRGTSMPFHSPQQHLPQHQDRTGTPSPAMPYCTLTPYIRRLVAMGLDSEGMLHGFFGDDWKLGVGPFHEVERRNYLFASKSANWLRVKASYDMDGGQYIPYIKPLQNATEAEIKSADNSWSEWLLMQDWMVGPRAPTDMEDIGFGGQPQQRRQSHHHHGQQRDEGGARVHIKREEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ14</accession>
    <name>G4MZ14_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Saccharopine dehydrogenase [NAD(+), L-lysine-forming]</fullName>
            <shortName evidence="14">SDH</shortName>
            <ecNumber evidence="5 14">1.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">Lysine--2-oxoglutarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MGG_01359</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NAD(+)-dependent cleavage of saccharopine to L-lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysin biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>L-saccharopine + NAD(+) + H2O = L-lysine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12440"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57951"/>
            <dbReference type="EC" id="1.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.7" evidence="5 14"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714288.1">
        <property type="nucleotide sequence ID" value="XM_003714240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ14"/>
    <dbReference type="SMR" id="G4MZ14"/>
    <dbReference type="FunCoup" id="G4MZ14">
        <property type="interactions" value="177"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZ14"/>
    <dbReference type="GeneID" id="2679732"/>
    <dbReference type="KEGG" id="mgr:MGG_01359"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01359"/>
    <dbReference type="eggNOG" id="KOG0172">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063085_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ14"/>
    <dbReference type="OMA" id="YFFFSHT"/>
    <dbReference type="OrthoDB" id="265306at2759"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00034"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004754">
        <property type="term" value="F:saccharopine dehydrogenase (NAD+, L-lysine-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd12188">
        <property type="entry name" value="SDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000217">
        <property type="entry name" value="Saccharopine dehydrogenase [NAD(+), L-lysine-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000627">
        <property type="entry name" value="Saccharopine dehydrogenase [NAD(+), L-lysine-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027281">
        <property type="entry name" value="Lys1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF23">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE [NAD(+), L-LYSINE-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018250">
        <property type="entry name" value="Saccharopine_DH_Lys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 14" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9 14 16" id="KW-0520">NAD</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="19">
        <location>
            <begin position="6"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="18">
        <location>
            <begin position="176"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="199"/>
            <end position="200"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="315"/>
            <end position="318"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="201"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR018250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EHA54481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="365" mass="40342" checksum="04DBAA5BF03EE427" modified="2011-12-14" version="1">MSSILHLRSETKPLEHRSALTPTTTKALIEAGYTVNVERSPVRIFDDAEFEAVGATLVPEGSWEQIPKDHIVIGLKELEEKDFPLKHTHIQFAHCYKNQGGWDKVLRRYHDGEGMLLDIEFLEKDGRRVAAFGYWAGFAGAALALQNWAWQLTNSGEPLPSVESRPNEAALVGDIKEALAGGKEKAGRLPRVIVIGALGRCGRGAVDMCKKAGIPDENILKWDMEETAPGGPFKEIVESDIFVNCIYLNKQIPPFVTMESLNTPERKLSVINDCSADTTNPFNPVPVYTVATTFDKPTVPVDGLSHGPPLSVISIDHLPSLLPREASESFSNDLLPYLLKLKDWKSDPVWAGAEKLFHEKVKTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ89</accession>
    <name>G4MZ89_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_08193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715169.1">
        <property type="nucleotide sequence ID" value="XM_003715121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ89"/>
    <dbReference type="GeneID" id="2678428"/>
    <dbReference type="KEGG" id="mgr:MGG_08193"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08193"/>
    <dbReference type="HOGENOM" id="CLU_1214983_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ89"/>
    <dbReference type="OMA" id="RIELVIH"/>
    <dbReference type="OrthoDB" id="10613047at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="228" mass="24743" checksum="CB919B63E9104AD9" modified="2011-12-14" version="1">MRDLGRESGKSDVVVKPTALGATFELDAAPTHEYITDSKRCQEGWAMMMMTTRGRDTRAAKGLVLSQNGSSCSDGFLQIDPPAHRLYAERRPPVAGRIELVIHAKSVREKQIISRIGRMPRTFQDTKTISKTRCGSTKVCGGARTVSGTSINGLVHATCCDVTHPGPFSSALNPSSSHALTVKIRPVAVAKLGVHSKPSQGGALALEESTVRRWWFVRDTLLPRSHPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZA6</accession>
    <name>G4MZA6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715186.1">
        <property type="nucleotide sequence ID" value="XM_003715138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZA6"/>
    <dbReference type="SMR" id="G4MZA6"/>
    <dbReference type="STRING" id="242507.G4MZA6"/>
    <dbReference type="GeneID" id="2678257"/>
    <dbReference type="KEGG" id="mgr:MGG_08206"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08206"/>
    <dbReference type="eggNOG" id="ENOG502RZT7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044590_1_0_1"/>
    <dbReference type="InParanoid" id="G4MZA6"/>
    <dbReference type="OMA" id="IAWRTAM"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052350">
        <property type="entry name" value="Metallo-dep_Lactonases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43569">
        <property type="entry name" value="AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43569:SF2">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="197"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="346" mass="38926" checksum="59B333CECED0A6F6" modified="2011-12-14" version="1">MSSTDFPIVDSHIHLYPEAELETFKWYTPDNPLGKRHSLAEYRAATGSPSNLKGFVFLETDRLNDEGRDWKLPLMEVEWLARIVDGKPRDGEGHTPEDAPLCLGIVPWAPMNLGAAKVEEYLEQAEKVAGPATWAKVKGFRYLLQDKPAASGLTEEFVESMRLLGKKGFIFDAGVDQHRRGRQQLDELVSMIDQAHDGIANEDDKVKFIINHFCKPNLEIINPADPSFIAWRAAMFTLGKCDRVYMKLSGMFSEMPESLRQRSMEEIFEAVQPWLAVVLAAFGPSRLMFASDWPVCTVGVDEEDAGGAWKKWKAVIDRLCRLASLSEEDQKMIWSGTAVKAYGIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZQ3</accession>
    <name>G4MZQ3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715224.1">
        <property type="nucleotide sequence ID" value="XM_003715176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZQ3"/>
    <dbReference type="GeneID" id="12985593"/>
    <dbReference type="KEGG" id="mgr:MGG_15843"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15843"/>
    <dbReference type="HOGENOM" id="CLU_2904648_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZQ3"/>
    <dbReference type="OrthoDB" id="5238325at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465568" evidence="1">
        <location>
            <begin position="23"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="62" mass="6339" checksum="581173CCB7DB2AC4" modified="2011-12-14" version="1">MGLKWWFLALFVPVLSTQALLGAHTGGLAHTIGGNGPKGTGKGGEARRCAVCQGSSLCVLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZW0</accession>
    <name>G4MZW0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding cassette sub-family B member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_13339</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711211.1">
        <property type="nucleotide sequence ID" value="XM_003711163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZW0"/>
    <dbReference type="SMR" id="G4MZW0"/>
    <dbReference type="STRING" id="242507.G4MZW0"/>
    <dbReference type="GeneID" id="5050271"/>
    <dbReference type="KEGG" id="mgr:MGG_13339"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13339"/>
    <dbReference type="eggNOG" id="KOG0056">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_9_1"/>
    <dbReference type="InParanoid" id="G4MZW0"/>
    <dbReference type="OMA" id="TIWENNA"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF654">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="58"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA51404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="206" mass="22512" checksum="C55D98A655ED2C88" modified="2011-12-14" version="1">MPELVGALSDAAPLRRILEKGTASARQTNGQKLGCTKGSLELVNVSFTYPGMDKPVIDRLNMAIKPATKVALLGPSGAGKTTLLRIFMRYLSPSSGVVLINGQNIENIDKDSFHNFVGIMPQMPYIFNTTVMENIRLGKADASDEEVYEGCRNAMIHDTIMARPHGDNTQIGEQGGFLSGGEKQRIEFARLFFKAAQGYFIRRANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZX2</accession>
    <name>G4MZX2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711223.1">
        <property type="nucleotide sequence ID" value="XM_003711175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZX2"/>
    <dbReference type="GeneID" id="12986978"/>
    <dbReference type="KEGG" id="mgr:MGG_16594"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16594"/>
    <dbReference type="HOGENOM" id="CLU_2979574_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZX2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="58" mass="6829" checksum="8BDEF8AE8A54D93D" modified="2011-12-14" version="1">MQTPAHDWPDQVYDKHSWDCDDQPHMLVNEARFLRNVYQVYSGSLRISGCVPTPMTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N038</accession>
    <name>G4N038_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712880.1">
        <property type="nucleotide sequence ID" value="XM_003712832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N038"/>
    <dbReference type="STRING" id="242507.G4N038"/>
    <dbReference type="GeneID" id="2675448"/>
    <dbReference type="KEGG" id="mgr:MGG_05318"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05318"/>
    <dbReference type="eggNOG" id="ENOG502QQUZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009044_0_0_1"/>
    <dbReference type="InParanoid" id="G4N038"/>
    <dbReference type="OMA" id="GRHFWAQ"/>
    <dbReference type="OrthoDB" id="66409at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005824">
        <property type="term" value="C:outer plaque of spindle pole body"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052809">
        <property type="entry name" value="Actin_polarity_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012860">
        <property type="entry name" value="Afi1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245:SF1">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07792">
        <property type="entry name" value="Afi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08616">
        <property type="entry name" value="SPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
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                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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                <person name="Gellesch M."/>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
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                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
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                <person name="Gearin G."/>
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                <person name="Goldberg J."/>
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                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711370.1">
        <property type="nucleotide sequence ID" value="XM_003711322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N184"/>
    <dbReference type="SMR" id="G4N184"/>
    <dbReference type="FunCoup" id="G4N184">
        <property type="interactions" value="126"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N184"/>
    <dbReference type="GeneID" id="2683386"/>
    <dbReference type="KEGG" id="mgr:MGG_07466"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07466"/>
    <dbReference type="eggNOG" id="KOG2655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017718_0_0_1"/>
    <dbReference type="InParanoid" id="G4N184"/>
    <dbReference type="OMA" id="EASHAEI"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000238">
        <property type="entry name" value="Cell division control 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="28"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA51563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="385" mass="44494" checksum="C701520165F7C9FE" modified="2011-12-14" version="1">MAPAATESASPIGIANLPNQRHKIVAKRGAAFTIMVAGESGLGKTTFINTLFSTTIKNYADHKRRHQKQIDKTVEIEITKAELEEKFFKVRLTVIDTPGFGDYVNNRDSWMPIIEFLDDQHESYMLQEQQPRRQDKIDLRVHACLYFIRPTGHTLKPLDIEVMKRLCSRVNLIPVIAKADTLSPADLARFKQRIRAVIDAQSIKIYQPPVEEDDEAAAQHARSLMAAMPFAVIGSEKDVKTGDGRIVKGRQYSWGVAEVENEDHCDFKKLRSILIRTHMLDLIHTTEELHYEAYRAQQMETRKFGEARPRKLDNPKFKEEEEALRKRFTEQVKIEEQRFRQWEQKLIAERDRLNKDLEHTHATIKQLEGELEQMQGSAARSHGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N192</accession>
    <name>G4N192_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cyclase/dehydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_07474</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with coenzyme Q.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the COQ10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711378.1">
        <property type="nucleotide sequence ID" value="XM_003711330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N192"/>
    <dbReference type="SMR" id="G4N192"/>
    <dbReference type="FunCoup" id="G4N192">
        <property type="interactions" value="133"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N192"/>
    <dbReference type="GeneID" id="2683394"/>
    <dbReference type="KEGG" id="mgr:MGG_07474"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07474"/>
    <dbReference type="eggNOG" id="KOG3177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079653_1_1_1"/>
    <dbReference type="InParanoid" id="G4N192"/>
    <dbReference type="OMA" id="QLHAAMM"/>
    <dbReference type="OrthoDB" id="292693at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901:SF10">
        <property type="entry name" value="COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="SPERM PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="4">
        <location>
            <begin position="68"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA51571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="246" mass="26418" checksum="FB843A197C3521EA" modified="2011-12-14" version="1">MAATLRQLARPALRAPSRHLAAPAIPTSHIHDQHRRFLPAASRATFFSLPGNPLGPPAPAHLTARRRLPYQASSLYDIIADVDSYASFLPYCTHSRVTAWRPGPDGKGRWPAAGELTAGWGPVTETYTSRLYCIPGRIVEAVSGKGTPGISPAEAKECGINLDEIIPGTKASEGGLFESLVTRWTVTQEAGTGGSRPWADVELSIRYQFANPMYQVATASVANEMAGLMVNAFEKRAKDLLGAGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1G6</accession>
    <name>G4N1G6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713040.1">
        <property type="nucleotide sequence ID" value="XM_003712992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1G6"/>
    <dbReference type="GeneID" id="12985949"/>
    <dbReference type="KEGG" id="mgr:MGG_16936"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16936"/>
    <dbReference type="HOGENOM" id="CLU_1138182_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1G6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="244" mass="27365" checksum="B960275628158774" modified="2011-12-14" version="1">MSFRVKDRENGVEGDKCHIKVSFEDSVVDQIIRTPFLKRSSTSNDNPTQTHDFSSLSRLREPVFTITNTPNKAVKRALKLNPQPELEHESGGETTSRLQQQSSQLSSCDGAVEVWLLVADPTLSKLYQTLRARCHDRQEVRLSSNNYKTQLAPAYGTPPSQPAWAAGGTQNRARRLHQQKARLPLSHILQHVHRAAEARTARLIKNNTACSGSRQYRQWKQKSLAGPKITFAAAAKAVRTITSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1Y5</accession>
    <name>G4N1Y5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713102.1">
        <property type="nucleotide sequence ID" value="XM_003713054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1Y5"/>
    <dbReference type="STRING" id="242507.G4N1Y5"/>
    <dbReference type="GeneID" id="12986051"/>
    <dbReference type="KEGG" id="mgr:MGG_16953"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16953"/>
    <dbReference type="HOGENOM" id="CLU_1245594_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1Y5"/>
    <dbReference type="OrthoDB" id="438641at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="222" mass="24201" checksum="2FEFC915CD57B7F9" modified="2011-12-14" version="1">MKKETIITCLFGWCHAQAALNHQTCSHRTGPSLIPADCPLPINHTAAKTEADWAPWSKQPVCFQPVHKPNTTDPYCLYTHPTFRSHGISVITTPGLAAALTSSLDDGVVPRHQRDHPSSPMSAQQRSSGALAYEIRDLPGRGKGLVATRPIRRWETVVVQFPSLVVLMDFWEAVESPKQSRRLLNRALKQLPAGEKGRILALGENKEGRGGSCLTGFGPGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2U3</accession>
    <name>G4N2U3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_13924</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:14761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="EC" id="2.3.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="3"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713199.1">
        <property type="nucleotide sequence ID" value="XM_003713151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2U3"/>
    <dbReference type="SMR" id="G4N2U3"/>
    <dbReference type="STRING" id="242507.G4N2U3"/>
    <dbReference type="GeneID" id="5049418"/>
    <dbReference type="KEGG" id="mgr:MGG_13924"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13924"/>
    <dbReference type="eggNOG" id="KOG1357">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_349493_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2U3"/>
    <dbReference type="OMA" id="FNSHYIE"/>
    <dbReference type="OrthoDB" id="2382073at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="130"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA53392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="749" mass="80728" checksum="D0D176ECF3E7F32F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2W7</accession>
    <name>G4N2W7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Benzoate 4-monooxygenase bphA</fullName>
            <ecNumber evidence="12">1.14.14.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Benzoate-para-hydroxylase A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Cytochrome P450 monooxygenase cyp53A1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_13928</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>benzoate + reduced [NADPH--hemoprotein reductase] + O2 = 4-hydroxybenzoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18033"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16150"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.92"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.92" evidence="12"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713223.1">
        <property type="nucleotide sequence ID" value="XM_003713175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2W7"/>
    <dbReference type="SMR" id="G4N2W7"/>
    <dbReference type="STRING" id="242507.G4N2W7"/>
    <dbReference type="GeneID" id="2683904"/>
    <dbReference type="KEGG" id="mgr:MGG_13928"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13928"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="InParanoid" id="G4N2W7"/>
    <dbReference type="OMA" id="TYDMVRD"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018664">
        <property type="term" value="F:benzoate 4-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11061">
        <property type="entry name" value="CYP67-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000053">
        <property type="entry name" value="Cytochrome P450 benzoate 4-monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF29">
        <property type="entry name" value="BENZOATE-PARA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 16 17" id="KW-0349">Heme</keyword>
    <keyword evidence="7 16 17" id="KW-0408">Iron</keyword>
    <keyword evidence="9 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 17 19" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00081895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00082391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA53416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="515" mass="57084" checksum="6E010CD5C739C702" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3B5</accession>
    <name>G4N3B5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mediator of RNA polymerase II transcription subunit 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_16681</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711600.1">
        <property type="nucleotide sequence ID" value="XM_003711552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3B5"/>
    <dbReference type="SMR" id="G4N3B5"/>
    <dbReference type="STRING" id="242507.G4N3B5"/>
    <dbReference type="GeneID" id="12984154"/>
    <dbReference type="KEGG" id="mgr:MGG_16681"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16681"/>
    <dbReference type="eggNOG" id="ENOG502T32G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_858087_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3B5"/>
    <dbReference type="OMA" id="HEANLHP"/>
    <dbReference type="OrthoDB" id="203279at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.160">
        <property type="entry name" value="Mediator of RNA polymerase II transcription subunit 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009332">
        <property type="entry name" value="Med22"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06179">
        <property type="entry name" value="Med22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA51793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="34842" checksum="91BC11A917616894" modified="2011-12-14" version="1">MSSFTMDRGQNSSLMDRHQAAITDITKHFGELVIGLSSPITAEDADTATSSQQAMRMQLESNALIASIEHLLSLTRQVRELWLVGPLLKPGEGERAADGQIDEQVESMTHILNQLRERVRNRQVGPHGTYIIKDRAVAAAPATDGATADASSAQPAQSSSAAPGGQMMEDAFDLVPSTQMEDVNPDVANESLFWSVMGEDHEANLHPDAAQNTGTATSNIHQVSAQDVAFAQEPTAFHNQAGGITENHGQGAFGSIEMNDQSGGDRSSDMPMLDTPMDPEARRLEYLLSQDHGLIDHLLPAICPSGSVRDAENMGAQLFTIEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4F4</accession>
    <name>G4N4F4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05106</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712629.1">
        <property type="nucleotide sequence ID" value="XM_003712581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4F4"/>
    <dbReference type="SMR" id="G4N4F4"/>
    <dbReference type="GeneID" id="2675559"/>
    <dbReference type="KEGG" id="mgr:MGG_05106"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05106"/>
    <dbReference type="eggNOG" id="ENOG502SDAI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_628616_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4F4"/>
    <dbReference type="OMA" id="QECANSD"/>
    <dbReference type="OrthoDB" id="3692311at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="117"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="256"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="323"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="121"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="436" mass="45187" checksum="B19EC56669E63F32" modified="2011-12-14" version="1">MTTPFQAFGLSCPAGGKFYICETGSEFVGCCASDPCNLTGCPQSDLRTSSFSPDEYSSLPTQECANSDSLWYTCAFNVPPFMGCCKTNPCANPKASCPTSSLGAAKLSSVDSLRERFLHPSPNSSAKPTPTSAPDRSPSNGAAPNTQSTTPSPQAVPSSNNNSGLSTGTIAGIAVGVSVLVLVAIAIIIWKCGWTAGKRRARRQAAEAAVPPAMGPGMTQKNNGYRDSGFPENSFPAENSYRDSFAPSAVTAVGSPRDTVYSKPGFDSNTSSMYGSPFPTGPTTPAPDPRYSTYSQQGYNPVGYSLVPNPAMPVVFEMESTEVRSELSGGGQPVAAPLPVPVQPPQKKQGDGQQRPPAQASQPQPQPSSPRSPQNGGLFPNTKPVSKPGSSKPSPIAPLPPPAQGNAPHSPSLPSPVSPPLVQGFPSPVSPPYQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4T2</accession>
    <name>G4N4T2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">54S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712704.1">
        <property type="nucleotide sequence ID" value="XM_003712656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4T2"/>
    <dbReference type="SMR" id="G4N4T2"/>
    <dbReference type="STRING" id="242507.G4N4T2"/>
    <dbReference type="GeneID" id="2675638"/>
    <dbReference type="KEGG" id="mgr:MGG_05167"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05167"/>
    <dbReference type="eggNOG" id="ENOG502QRUI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044515_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4T2"/>
    <dbReference type="OMA" id="YKPPEFR"/>
    <dbReference type="OrthoDB" id="360689at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047865">
        <property type="entry name" value="Ribosomal_uL10_bac_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="328"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="38617" checksum="F67CD1228F8B3B15" modified="2011-12-14" version="1">MPPRVQCPSIGSAIRQQSRQRISPRHRPTLQTVTPVLVDSSVLARRTYATAAPLSRLGGLQLPADYVPPTQPPSARRPETRKSQLLRAYTSLLRSTPLTLIFQHSNLTSQEWSAVRRELRAALAKVPIPATPEGVPPPVDIVKNIQLQVIRTRIFDQAFKVVEFFDPEAAAAKTPGMKKYNHDLSKAAYEATSKIDLDAVPDSSMYKQIAPLLVGPVALVTFPAVSPDHVAAVLRTLAPSAPAFPAPTRRACPSYHEPIARSGIQKLLLVGGRVEDRVFDLDGVKWLGGIQGGRDALRAQVVHMLQSAGLGLTMALEGASKSLWLTMESRRTQMEDEAKGPEEAAEKKEDEAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4Y9</accession>
    <name>G4N4Y9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">YeeE/YedE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06056</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711908.1">
        <property type="nucleotide sequence ID" value="XM_003711860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4Y9"/>
    <dbReference type="SMR" id="G4N4Y9"/>
    <dbReference type="STRING" id="242507.G4N4Y9"/>
    <dbReference type="GeneID" id="2683919"/>
    <dbReference type="KEGG" id="mgr:MGG_06056"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06056"/>
    <dbReference type="eggNOG" id="ENOG502RZM3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053006_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4Y9"/>
    <dbReference type="OMA" id="MIIGSRM"/>
    <dbReference type="OrthoDB" id="10254418at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp_TsuA/YedE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30574">
        <property type="entry name" value="INNER MEMBRANE PROTEIN YEDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30574:SF1">
        <property type="entry name" value="SULPHUR TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA52101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="338" mass="33826" checksum="DD4665AA88D91A72" modified="2011-12-14" version="1">MAASILPGLLSGAAFGASLTGAGVYQPSVIMGQLELEDFHMLQTLLTATAGSAVLASLLQGLGYVKLSPRSFSSFNLLGSADANFVGGALLGGGMALAGSCPGTVAAQIGLGIPSGYWTFVGGVAGGIVWTGFVRPWMARRNAQEGAKTAGKKPCLTVHECVGVSPRVGLVVFEALAAAAIGAALNVKTLSANGTRHIEPVVGGLLIAGAQLVSLLIRRSMVGTSTVFDELGELFWWAVSGGQRPKSMSALAFVTGIILGSATLARAFPTALAGTGFSDVSATRAALGGFAMAIGSRVAGGCTAGHGISGMSLMSVSSIITVASMFISGIVVTKALSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5G4</accession>
    <name>G4N5G4_PYRO7</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <gene>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711171.1">
        <property type="nucleotide sequence ID" value="XM_003711123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5G4"/>
    <dbReference type="GeneID" id="12986972"/>
    <dbReference type="KEGG" id="mgr:MGG_16586"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16586"/>
    <dbReference type="HOGENOM" id="CLU_2306662_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5G4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="100" mass="10976" checksum="A92C5B6024C1076A" modified="2011-12-14" version="1">MPKYYSQGTDCGSGVELKPAHLDTSPWVPESVLGKHLRKNLHLFLLDIPAKESCFKAAIMSAESERTAPVASCLFPNPLSGVWGLSVPWRYTEHVPSTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5P8</accession>
    <name>G4N5P8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphomethylpyrimidine kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712845.1">
        <property type="nucleotide sequence ID" value="XM_003712797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5P8"/>
    <dbReference type="SMR" id="G4N5P8"/>
    <dbReference type="FunCoup" id="G4N5P8">
        <property type="interactions" value="694"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5P8"/>
    <dbReference type="GeneID" id="12985737"/>
    <dbReference type="KEGG" id="mgr:MGG_16900"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16900"/>
    <dbReference type="eggNOG" id="KOG2598">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020520_2_1_1"/>
    <dbReference type="InParanoid" id="G4N5P8"/>
    <dbReference type="OMA" id="FWEMFPY"/>
    <dbReference type="OrthoDB" id="10028886at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008902">
        <property type="term" value="F:hydroxymethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050334">
        <property type="term" value="F:thiaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19367">
        <property type="entry name" value="TenA_C_ScTHI20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.910.10:FF:000003">
        <property type="entry name" value="Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000034">
        <property type="entry name" value="Putative hydroxymethylpyrimidine/ phosphomethylpyrimidine kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027574">
        <property type="entry name" value="Thiaminase_II"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00097">
        <property type="entry name" value="HMP-P_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04306">
        <property type="entry name" value="salvage_TenA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858:SF17">
        <property type="entry name" value="HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PHOSPHOMETHYLPYRIMIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine kinase/Phosphomethylpyrimidine kinase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Thiaminase-2/PQQC" evidence="1">
        <location>
            <begin position="301"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="55081" checksum="4CBC0B78BC11E192" modified="2011-12-14" version="1">MTGKRVLVVAGSDSSGGAGLEADQKTLAAHGCYAMTATAALTAQNTQGVFAVHHVPSKFVRKQIDLCFDDVGVDVVKTGMLAVAETIKELAEALTSRNFDGKLVVDPVMVATTGAKLLPVEAVTELVKHLIPLTTVLTPNVPEASLLLTTAGFEQPAIKNVTDLETIGRNLLTLGPQWVLVKGGHSPLRQDYSVAEKPEERQIMVDVLVGADGQVFRIESGFQDSKNTHGTGCTLASAIAANLSIGMDVLGSVKAACRYVQAALKAAPGLGQGNGPLGHFHSLSIRPFAPGNFIEYVLERPDVAPIWERYIKHPFVLGLGDGTLPLSSFKSYLVQDYLYLIQFARANALASYKSKNLADISAAAAIVLHIDRETQLHLDYCKGFGLTKEEMEQSEEHVACTAYSRYVLDVGQSSDYVALQMALAPCLLGYGAIAKHLHADPKSKRDGSPYWTWIQNYVADDYVQAVKTGSELLERHAMLQSPSRINELVEVFKHATKMEIAFWEMFPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4N793</accession>
    <name>G4N793_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H3-like centromeric protein CSE4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">CENP-A homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">CENPA homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_06445</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of centromeric nucleosomes, where DNA is wrapped around a histone octamer core. The octamer contains two molecules each of H2A, H2B, CSE4/CENPA and H4 assembled in one CSE4-H4 heterotetramer and two H2A-H2B heterodimers. Interacts with the inner kinetochore.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717122.1">
        <property type="nucleotide sequence ID" value="XM_003717074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N793"/>
    <dbReference type="SMR" id="G4N793"/>
    <dbReference type="STRING" id="242507.G4N793"/>
    <dbReference type="GeneID" id="2684600"/>
    <dbReference type="KEGG" id="mgr:MGG_06445"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06445"/>
    <dbReference type="eggNOG" id="KOG1745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078295_3_3_1"/>
    <dbReference type="InParanoid" id="G4N793"/>
    <dbReference type="OMA" id="VHLFEDC"/>
    <dbReference type="OrthoDB" id="842664at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000087">
        <property type="entry name" value="Probable histone 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810:SF1">
        <property type="entry name" value="HISTONE H3-LIKE CENTROMERIC PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810">
        <property type="entry name" value="HISTONE H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="40"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA50803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="135" mass="15286" checksum="05C6039C56C7277E" modified="2011-12-14" version="1">MPPQKVKKAGAKKTVPGASRDSGVMPGDPIPQKKSRRYRPGTLALREIRRYQKSTDLLMRKLPFARLVREVALSVRPVDEGFRWQSHAILALQEAAEAFLVKLFEDTNLCAIHAKRVTIMQKDIQLARRIRADGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7K1</accession>
    <name>G4N7K1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Guanylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717177.1">
        <property type="nucleotide sequence ID" value="XM_003717129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7K1"/>
    <dbReference type="SMR" id="G4N7K1"/>
    <dbReference type="STRING" id="242507.G4N7K1"/>
    <dbReference type="GeneID" id="2684549"/>
    <dbReference type="KEGG" id="mgr:MGG_06394"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06394"/>
    <dbReference type="eggNOG" id="KOG0707">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG2491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017925_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7K1"/>
    <dbReference type="OMA" id="EYHTENV"/>
    <dbReference type="OrthoDB" id="10257415at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021861">
        <property type="entry name" value="THO_THOC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265:SF0">
        <property type="entry name" value="HPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265">
        <property type="entry name" value="THO COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11957">
        <property type="entry name" value="efThoc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="2">
        <location>
            <begin position="609"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="810" mass="90773" checksum="F0CBAFB4D26E72A8" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N858</accession>
    <name>G4N858_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06306</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717278.1">
        <property type="nucleotide sequence ID" value="XM_003717230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N858"/>
    <dbReference type="SMR" id="G4N858"/>
    <dbReference type="GeneID" id="2684461"/>
    <dbReference type="KEGG" id="mgr:MGG_06306"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06306"/>
    <dbReference type="eggNOG" id="KOG3720">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030431_3_1_1"/>
    <dbReference type="InParanoid" id="G4N858"/>
    <dbReference type="OMA" id="SWPPFTS"/>
    <dbReference type="OrthoDB" id="69928at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:inositol hexakisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF110">
        <property type="entry name" value="2-PHOSPHOXYLOSE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="507" mass="56418" checksum="69EFEA2D98A43A5A" modified="2011-12-14" version="1">MTTLQPRAPYTDEELRTLYPSGLDLQLVQVLMRHGERTPVSSRFQNAGLKPFWPYCRVAKELRSVILEPGNSGTLSTLEWSRRIETFGHDDEPRVAAGPRGEVDAVCDMGMLTDEGRATTYALGQRLRRLYVEQLGFLPATAAGGVDDMYLRSTPIPRALESLQQAFSALYPPATRLPAADGSAFRPPTIVTRTPGDETLYPNDAGCRRLAALSRAFAQRTADRWNDSADMEYLNRLWAKWMPADSPRVAVDSRPRLSGIMDTVNSTLGHGPETRLPREFYDKKAIAITEKIGVEEWFSGYKESREYRALGIGSLMGDIVGRMISSVEGPAAEGTERKNESRNYASVKFGLSGCHDTTLAGILASLGAFETDKWPPYTSHVAIEMFRDPTRATATAVLPTNQGWWSALSSKVRKESGGIGRRTMDELSPSETERLDGYYVRVRYNDEPVTIPGCKIPGNHLYGNENFCTLRAFKSIVDKYTPRNWKEDCRRSTTDPVIPAKPEPAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4N885</accession>
    <name>G4N885_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isoflavone reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03473</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716451.1">
        <property type="nucleotide sequence ID" value="XM_003716403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N885"/>
    <dbReference type="SMR" id="G4N885"/>
    <dbReference type="GeneID" id="2676815"/>
    <dbReference type="KEGG" id="mgr:MGG_03473"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03473"/>
    <dbReference type="eggNOG" id="ENOG502SHHA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_3_3_1"/>
    <dbReference type="InParanoid" id="G4N885"/>
    <dbReference type="OMA" id="ADYGSCD"/>
    <dbReference type="OrthoDB" id="9984533at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05259">
        <property type="entry name" value="PCBER_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045312">
        <property type="entry name" value="PCBER-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF9">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="317" mass="34329" checksum="35F202CE56C20FF5" modified="2011-12-14" version="1">MAIHKVVLVGANGDLGGAVLRGLVDAGTFEVKVLKRQSSSSSNDNLPSSVQLLTVPDAWTEPDLTAALRGADAVVACFALREDPPRAHLVLASAAAAAGVTRYIPADFGSVDSRAPRARELVPLFGKKAAVRALLDSLAESTPTFSWTSIVCGHFFDWGLRENFLHVDLKARTHEILDQGEQRSSLSTLAQVGRAVVAILNKTDETRNRTVFIQSFCVSQNDVQAALEKATGTTAGDGEGQWKKTYIPAEQFISEKVVLRDAGDKQAIEDLVFALGVIDGDWEKKDEFSMDLLGLQPEDLDKVVKEVVDEVEKQRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8Y3</accession>
    <name>G4N8Y3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ricin B lectin:Parallel beta-helix</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716596.1">
        <property type="nucleotide sequence ID" value="XM_003716548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8Y3"/>
    <dbReference type="SMR" id="G4N8Y3"/>
    <dbReference type="GeneID" id="2676725"/>
    <dbReference type="KEGG" id="mgr:MGG_03356"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03356"/>
    <dbReference type="eggNOG" id="ENOG502R351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041546_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8Y3"/>
    <dbReference type="OMA" id="DVCGTIN"/>
    <dbReference type="OrthoDB" id="5576103at2759"/>
    <dbReference type="PHI-base" id="PHI:3213"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005680472" evidence="1">
        <location>
            <begin position="21"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="355" mass="37146" checksum="4AD4ECB54AD506DF" modified="2011-12-14" version="1">MARFTSLIAAVLATIGAVKAQCGAGNPDARVTGSGNNFQAVRGSNTVYSGSDYRAAIQAALDSIGSGQRVAVIASGSIGANTISISSGKTFEGCGTINVGNRNGRGAIESLNTQGVKIPYLTMTGNPYFGLRFYGTRDLTLGQITMNLSGGLGIRFDRDNPDNFNVRMGTITVTGAGSHAVETWNIDGLVIDRVIARNVGESGLLVQKTRNAQIGIVDGNNVGTGTGYATLRFANNNGQNPNGNYNTNIWVDQVISRGGGRGVFCVSQSGAAVIRTVDLAKNGNNAILIENCYNLSIRGGTVNGGGEVRVAARSEFPNNRDLWITLRVDNTSVRESPCGTNVNWSLTGNGQRALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9Q6</accession>
    <name>G4N9Q6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_16997</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715882.1">
        <property type="nucleotide sequence ID" value="XM_003715834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9Q6"/>
    <dbReference type="SMR" id="G4N9Q6"/>
    <dbReference type="STRING" id="242507.G4N9Q6"/>
    <dbReference type="GeneID" id="12986833"/>
    <dbReference type="KEGG" id="mgr:MGG_16997"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16997"/>
    <dbReference type="eggNOG" id="KOG0351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001104_6_1_1"/>
    <dbReference type="InParanoid" id="G4N9Q6"/>
    <dbReference type="OMA" id="HISEEWH"/>
    <dbReference type="OrthoDB" id="5244177at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022698">
        <property type="entry name" value="OrsD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF154">
        <property type="entry name" value="RECQ HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12013">
        <property type="entry name" value="OrsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="984"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="976"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="732"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="832"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="734"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="758"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="832"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA49563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1140" mass="130584" checksum="3EAD7C6BE87C4A94" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9R4</accession>
    <name>G4N9R4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_17003</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA49571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003715842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9R4"/>
    <dbReference type="SMR" id="G4N9R4"/>
    <dbReference type="FunCoup" id="G4N9R4">
        <property type="interactions" value="773"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9R4"/>
    <dbReference type="GeneID" id="12986830"/>
    <dbReference type="KEGG" id="mgr:MGG_17003"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17003"/>
    <dbReference type="eggNOG" id="KOG0569">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_5_1"/>
    <dbReference type="InParanoid" id="G4N9R4"/>
    <dbReference type="OMA" id="WAITASF"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="18"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="226"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA49571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="518" mass="54423" checksum="23E83524A90614C4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="79" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9S1</accession>
    <name>G4N9S1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="10">PPIase</shortName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_10681</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715897.1">
        <property type="nucleotide sequence ID" value="XM_003715849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9S1"/>
    <dbReference type="SMR" id="G4N9S1"/>
    <dbReference type="STRING" id="242507.G4N9S1"/>
    <dbReference type="GeneID" id="2682882"/>
    <dbReference type="KEGG" id="mgr:MGG_10681"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10681"/>
    <dbReference type="eggNOG" id="KOG0415">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018791_2_1_1"/>
    <dbReference type="InParanoid" id="G4N9S1"/>
    <dbReference type="OMA" id="APKCCEN"/>
    <dbReference type="OrthoDB" id="2083at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01921">
        <property type="entry name" value="cyclophilin_RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12235">
        <property type="entry name" value="RRM_PPIL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000015">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000287">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035542">
        <property type="entry name" value="CRIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035538">
        <property type="entry name" value="Cyclophilin_PPIL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="12">
        <location>
            <begin position="6"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="13">
        <location>
            <begin position="257"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="376"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="392"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="436"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="448"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA49578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="505" mass="57243" checksum="9E8CD1CBCB030B5C" modified="2011-12-14" version="1">MSVLLETSAGDIVIDLLVDYAPKLCENFLKLCKVKYYNFSPVHSVQKNFSFQTGDPLGPMAPQSDGGSSIWGVLSGDPAQRTFPALFHPKLRHAERGTVSMATAPHPTDPDTRLAGSQFIVTLGEDTDFIDGKAAIFGKVVEGFDTLEKINEAIIDEKGHPLVDIRIKHTVILDDPYPDPAGLREPSSSPAPTPAQIATVRIAEDEAAKLAEEDAEGDEDRAAAAEKQRREREAKAQALTLEMMGDLPFAEVKPPENVLFVCKLNPVTQDADLELIFSRFGKILSCEVIRDSKTGDSLQYAFIEFEDKAACETAYFKMQGVLIDDRRIHVDFSQSVSKLSNAWRTDANDKRRKQAAKGRGGWGGVDELEKWRKYREDDGRDDRPDSYGMVYGKEEMQGRHERQKAGPGHDAEKPREGGGDRNGYDQRRDRASDSRRRSRSRSPRRERHRDSRDGRRRDDRDSGSKRGGERSRHDRDRGQERHNRGNDYDRDRRRDRDRRDDYRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAE5</accession>
    <name>G4NAE5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716809.1">
        <property type="nucleotide sequence ID" value="XM_003716761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAE5"/>
    <dbReference type="STRING" id="242507.G4NAE5"/>
    <dbReference type="GeneID" id="12985431"/>
    <dbReference type="KEGG" id="mgr:MGG_17134"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17134"/>
    <dbReference type="eggNOG" id="ENOG502RGRA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099116_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAE5"/>
    <dbReference type="OMA" id="STENWKA"/>
    <dbReference type="OrthoDB" id="5239545at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="242" mass="26568" checksum="A7BF8A5D2BBCAB0F" modified="2011-12-14" version="1">MPMKWDDGAVAMLCGTIVAILGTDGITQEQKDAIVERMNSAGYDVAWNGISIHFYKMPRFEDIKGDLFEAIWRATAPTFGPEQQSAVITHLKAKGIEMTWDAVRAPGLHEDLVAVLLKQDLVSTENWKAVLAGMHEAQYQFTWRGFEQHLQKLKKKDPNGPGAATPSTPKGKKTAASATGSAAKSTSKRGRKPAKKVLDADDDEEDDFDASPSKKTKTEDKAENDAKVDRVKAEHVEEDDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB46</accession>
    <name>G4NB46_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718392.1">
        <property type="nucleotide sequence ID" value="XM_003718344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB46"/>
    <dbReference type="SMR" id="G4NB46"/>
    <dbReference type="STRING" id="242507.G4NB46"/>
    <dbReference type="GeneID" id="5050693"/>
    <dbReference type="KEGG" id="mgr:MGG_11537"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11537"/>
    <dbReference type="eggNOG" id="ENOG502SJF8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_721752_0_0_1"/>
    <dbReference type="InParanoid" id="G4NB46"/>
    <dbReference type="OMA" id="PRIYACF"/>
    <dbReference type="OrthoDB" id="2906425at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd05120">
        <property type="entry name" value="APH_ChoK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF15">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="54"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="383" mass="41815" checksum="829613DD4EE2F001" modified="2011-12-14" version="1">MGPPTNLELNAKREEHCIQVTPERKYYRYADTWVKRSLKPSEWQKHGGYMFVPKFSTERVLNEGACLAFLAEHTEIPVPRIYACFEDDGAAYLITEFVEGTPMSQLPPEQQKHVVIELEQHLETLKQITSPNWGGPTGHVLPPYRVMRRSKGHPWHMRPRDDDSLVFCHNDLSASNVLVDPYTLKINAIVDWEYAGFYPPEFDSPFYLRAGPPVALQGEYDDVDELCRIIDSERVYLENQQHTAPQTPVTPYGPPGARGSGQSANGGQQQQQQSGPNGGHTRGQGPPPQAGFAHQGNSQNGGGHGGQQQGMGGRPFLGPAGSFTAQRSISPGLHAQRAMSPAMHGQRAVSPGVAHAYSGPNGHGGHNGPSGHNGHNGSGPYAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBP4</accession>
    <name>G4NBP4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718536.1">
        <property type="nucleotide sequence ID" value="XM_003718488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBP4"/>
    <dbReference type="STRING" id="242507.G4NBP4"/>
    <dbReference type="GeneID" id="2674654"/>
    <dbReference type="KEGG" id="mgr:MGG_00521"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00521"/>
    <dbReference type="eggNOG" id="KOG1143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006343_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBP4"/>
    <dbReference type="OMA" id="LKHRHEM"/>
    <dbReference type="OrthoDB" id="5342685at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF30">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="2">
        <location>
            <begin position="286"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="873" mass="93115" checksum="F59EE756DF05DE5D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCL6</accession>
    <name>G4NCL6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GPN-loop GTPase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00382</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718694.1">
        <property type="nucleotide sequence ID" value="XM_003718646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCL6"/>
    <dbReference type="SMR" id="G4NCL6"/>
    <dbReference type="FunCoup" id="G4NCL6">
        <property type="interactions" value="909"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NCL6"/>
    <dbReference type="GeneID" id="2674391"/>
    <dbReference type="KEGG" id="mgr:MGG_00382"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00382"/>
    <dbReference type="eggNOG" id="KOG1534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037460_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCL6"/>
    <dbReference type="OMA" id="LYTHMTV"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17872">
        <property type="entry name" value="GPN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000552">
        <property type="entry name" value="GPN-loop GTPase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030228">
        <property type="entry name" value="Gpn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF7">
        <property type="entry name" value="GPN-LOOP GTPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA49110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="300" mass="33679" checksum="FC745DD997E92968" modified="2011-12-14" version="1">MSKFGVMVMGPAGAGKSTFCASLITHLRMNRRSSFYVNLDPAAESFEHTPDLDIKDLISLEDVMEEMGLGPNGGLIYCFEFLMENLDFLTEALESLTEEYLIIIDMPGQIELYTHIPILPALVKFLTQSGALDIRLCAAYLLEATFVVDRPKFFAGTLSAMSAMIMLEVPHINILSKMDLVKGQVRKRDLKRFINPDVSLLEDDPANKGNQAAAGDEDFDEEQRPPQDTDVLMRGASFRRLNKAVANLIEQFSMVSYLRLDSSDEDSVGAILSYIDDCIQFHEAQEPRELKDEEFEEAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCQ6</accession>
    <name>G4NCQ6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_00349</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718734.1">
        <property type="nucleotide sequence ID" value="XM_003718686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCQ6"/>
    <dbReference type="SMR" id="G4NCQ6"/>
    <dbReference type="FunCoup" id="G4NCQ6">
        <property type="interactions" value="920"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NCQ6"/>
    <dbReference type="GeneID" id="2675125"/>
    <dbReference type="KEGG" id="mgr:MGG_00349"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00349"/>
    <dbReference type="eggNOG" id="KOG0400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090139_2_0_1"/>
    <dbReference type="InParanoid" id="G4NCQ6"/>
    <dbReference type="OMA" id="MHTRRKG"/>
    <dbReference type="OrthoDB" id="623277at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.10:FF:000003">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.130:FF:000001">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_uS15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_uS15_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_uS15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006331">
        <property type="entry name" value="PRK08561.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15P/S13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885:SF6">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS15 N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA49150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="151" mass="16855" checksum="3A92566F45BD26D7" modified="2011-12-14" version="1">MGRMHSNGKGISASAIPYSRNPPAWLKTTPDQVVEQICKLARKGATPSQIGVVLRDSHGIAQVKIVTGNKILRILKSNGLAPDIPEDLYMLIKKAVSVRKHLERNRKDKDSKFRLILIESRIHRLARYYKTVGVLPPTWKYESATASTLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDQ3</accession>
    <name>G4NDQ3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718075.1">
        <property type="nucleotide sequence ID" value="XM_003718027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDQ3"/>
    <dbReference type="STRING" id="242507.G4NDQ3"/>
    <dbReference type="GeneID" id="2674534"/>
    <dbReference type="KEGG" id="mgr:MGG_00890"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00890"/>
    <dbReference type="eggNOG" id="ENOG502S19W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005247_0_1_1"/>
    <dbReference type="InParanoid" id="G4NDQ3"/>
    <dbReference type="OMA" id="AGMMMQE"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="945" mass="107899" checksum="37E2D8AD8ECF7365" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDX2</accession>
    <name>G4NDX2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718938.1">
        <property type="nucleotide sequence ID" value="XM_003718890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDX2"/>
    <dbReference type="GeneID" id="12985080"/>
    <dbReference type="KEGG" id="mgr:MGG_17517"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17517"/>
    <dbReference type="InParanoid" id="G4NDX2"/>
    <dbReference type="OrthoDB" id="10323769at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="74" mass="8087" checksum="2026687266AC2DCE" modified="2011-12-14" version="1" fragment="single">RASSAGRQLKRPKSQVGAAILWLFLRSRPQTRSSATSRQRTGLTSIHASAAKYTYKIPYNLPGRGLIQSLGDST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDY7</accession>
    <name>G4NDY7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HMG box-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_00866</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718106.1">
        <property type="nucleotide sequence ID" value="XM_003718058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDY7"/>
    <dbReference type="SMR" id="G4NDY7"/>
    <dbReference type="STRING" id="242507.G4NDY7"/>
    <dbReference type="GeneID" id="2674333"/>
    <dbReference type="KEGG" id="mgr:MGG_00866"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00866"/>
    <dbReference type="eggNOG" id="KOG3854">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012966_3_2_1"/>
    <dbReference type="InParanoid" id="G4NDY7"/>
    <dbReference type="OMA" id="FAWECVE"/>
    <dbReference type="OrthoDB" id="20772at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035240">
        <property type="entry name" value="SprT_Zn_ribbon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099:SF0">
        <property type="entry name" value="GERM CELL NUCLEAR ACIDIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23099">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17283">
        <property type="entry name" value="Zn_ribbon_SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="603"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="603"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="151"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="587"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="644"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="674" mass="74828" checksum="1E4D581DA9FB8FE4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEI1</accession>
    <name>G4NEI1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719042.1">
        <property type="nucleotide sequence ID" value="XM_003718994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEI1"/>
    <dbReference type="GeneID" id="12985132"/>
    <dbReference type="KEGG" id="mgr:MGG_17537"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17537"/>
    <dbReference type="HOGENOM" id="CLU_2427456_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEI1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="91" mass="10050" checksum="B64DE54D3355AC1F" modified="2011-12-14" version="1">MRRHLQIFLSGRLPCNTPRKNLNWIRSIGQDGPGRAPSNDVMRSNVVPGPTRRKPGLVGEPAHLARQLAPVLRSRTSGTLSTFDRRGEGPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF41</accession>
    <name>G4NF41_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosyl transferase family 25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08232</name>
        <name evidence="7" type="ORF">MGG_14727</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15</strain>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 25 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715854.1">
        <property type="nucleotide sequence ID" value="XM_003715806.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719144.1">
        <property type="nucleotide sequence ID" value="XM_003719096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF41"/>
    <dbReference type="CAZy" id="GT25">
        <property type="family name" value="Glycosyltransferase Family 25"/>
    </dbReference>
    <dbReference type="GeneID" id="2678510"/>
    <dbReference type="GeneID" id="5049419"/>
    <dbReference type="KEGG" id="mgr:MGG_08232"/>
    <dbReference type="KEGG" id="mgr:MGG_14727"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08232"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14727"/>
    <dbReference type="eggNOG" id="KOG4179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032992_0_0_1"/>
    <dbReference type="OMA" id="AHANIWN"/>
    <dbReference type="OrthoDB" id="47375at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06532">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050757">
        <property type="entry name" value="Collagen_mod_GT25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730:SF53">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10730">
        <property type="entry name" value="PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 25" evidence="6">
        <location>
            <begin position="90"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="41"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA49560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA56047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="393" mass="43640" checksum="C20B79D55FE37FA1" modified="2011-12-14" version="1">MLAEKGPSWLSQGGRRPMGILLAVAAFIFLMLTYASFPSQRRPPPSNLMTPSAPSRQQPAVPGPQASTPHFVSVDDAASNGTVGVDSIIFLNLPHRHDRFDAMAIQAHLSKLKISRFPAVDPSTLTSQGMPPMENDQANLKEGEKGCFRAHANVWQHMLEKGIDSALVLESDAGWDINFRPIMGRLNGGFRKLLQEEHPDNRDVFEENPDDPWLARSGTWDILSIGHCVDARGGGRYVIYDDPHAPSTNYQVEVDEGQAVLNRKRIVYRAQTLFCTTGYLVSLSGAARMLVRMNWKFDAPVDVIMNEMIGNGELRAYSMHQRLVVQWTYIPGIGKGRSNSDIQSDGKPEPSTPEGWDRAKKDRSVYDYHGGYADAAIVESALQRAWHEVIGDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFR4</accession>
    <name>G4NFR4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17576</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA46871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003719190.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NFR4"/>
    <dbReference type="SMR" id="G4NFR4"/>
    <dbReference type="GeneID" id="12985211"/>
    <dbReference type="KEGG" id="mgr:MGG_17576"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17576"/>
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    <dbReference type="InParanoid" id="G4NFR4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="86" mass="9904" checksum="77E3D5741CB0F025" modified="2011-12-14" version="1">MRLSYREKNQEAVCLPFPSTPTWTLIGTEEQGIGLENLLTLLEANNGQFLSHRKALLADMPCKMENDFPRIQKDEVWRPINDTICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGA4</accession>
    <name>G4NGA4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pleiotropic drug resistance protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_10410</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719428.1">
        <property type="nucleotide sequence ID" value="XM_003719380.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NGA4"/>
    <dbReference type="FunCoup" id="G4NGA4">
        <property type="interactions" value="46"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGA4"/>
    <dbReference type="GeneID" id="2682022"/>
    <dbReference type="KEGG" id="mgr:MGG_10410"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10410"/>
    <dbReference type="eggNOG" id="KOG0065">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_57_4_1"/>
    <dbReference type="InParanoid" id="G4NGA4"/>
    <dbReference type="OMA" id="ACGYFVQ"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001433">
        <property type="entry name" value="ABC transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF119">
        <property type="entry name" value="ROA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="545"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="568"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="689"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1157"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1190"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1240"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1266"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1297"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1386"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="108"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="741"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1045"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1045"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1074"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1412" mass="156045" checksum="9CBD85EA600BD008" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGB0</accession>
    <name>G4NGB0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_17622</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003719434.1">
        <property type="nucleotide sequence ID" value="XM_003719386.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NGB0"/>
    <dbReference type="SMR" id="G4NGB0"/>
    <dbReference type="GeneID" id="12985910"/>
    <dbReference type="KEGG" id="mgr:MGG_17622"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17622"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_6_1"/>
    <dbReference type="InParanoid" id="G4NGB0"/>
    <dbReference type="OMA" id="YGSFGCI"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF92">
        <property type="entry name" value="AGL026WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="55"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="506" mass="56271" checksum="3BA37796251668EC" modified="2011-12-14" version="1">MAANQADVVKVLKTPGGSLHLETIDADLKVTEDGVLIEDREHKEKALVRKIDSRMMPLMMLLYVLNYIDRNNIATARLGSFEKDIGLHGTQYNTVISIFFVGYILTQIPTNMILNKVRPSLFLPAVMICWGSVSACTGAVQNYSGMIALRFMLGFVEAPFFPGALFLFSCWYTKKELAKRISILFAAGQMAGAFSGFLGSAIMGGMNGVAGIADWRWLFIIEGVMTIPVAFLTYFVVPDYPTNTKWLSDEERVLAVLRIAEEANEEDDREEVSAFQGLKLAFTDVNLYLIWMMQLGLNTAAAFTNFFPTIVQTLGYPQRETLLLSSPPYVFAAILGISNSWHSDAKRERWLHILWPQVFACVGFIISATTLNVAARYTATFMMMSIYGSFGAILSWVSTSLPRPSAKRAVAYAFVNAMSNLASIYASYFYPATQGPQYWQANIANVAFSGMCIAMATALRFYLSWRNKKLDDASAEDMAAEGTANGTKTKALAARWQCHPDYRYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGB1</accession>
    <name>G4NGB1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_17623</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719435.1">
        <property type="nucleotide sequence ID" value="XM_003719387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGB1"/>
    <dbReference type="SMR" id="G4NGB1"/>
    <dbReference type="STRING" id="242507.G4NGB1"/>
    <dbReference type="GeneID" id="12985911"/>
    <dbReference type="KEGG" id="mgr:MGG_17623"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17623"/>
    <dbReference type="eggNOG" id="ENOG502RXEV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014019_1_0_1"/>
    <dbReference type="InParanoid" id="G4NGB1"/>
    <dbReference type="OMA" id="GNWTMSD"/>
    <dbReference type="OrthoDB" id="648861at2759"/>
    <dbReference type="PHI-base" id="PHI:3311"/>
    <dbReference type="PHI-base" id="PHI:5661"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF49">
        <property type="entry name" value="LYSINE BIOSYNTHESIS REGULATORY PROTEIN LYS14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="66"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="544"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="544"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="656" mass="72949" checksum="0EC4A399F84E85BA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGW9</accession>
    <name>G4NGW9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 12">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_04004</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 12">Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Vacuole membrane</location>
            <topology evidence="1 12">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the beta-catenin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719846.1">
        <property type="nucleotide sequence ID" value="XM_003719798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGW9"/>
    <dbReference type="SMR" id="G4NGW9"/>
    <dbReference type="FunCoup" id="G4NGW9">
        <property type="interactions" value="120"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGW9"/>
    <dbReference type="GeneID" id="2677274"/>
    <dbReference type="KEGG" id="mgr:MGG_04004"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04004"/>
    <dbReference type="eggNOG" id="KOG4224">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021483_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGW9"/>
    <dbReference type="OMA" id="VWDKPDG"/>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071563">
        <property type="term" value="C:Myo2p-Vac17p-Vac8p transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051656">
        <property type="term" value="P:establishment of organelle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061724">
        <property type="term" value="P:lipophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000425">
        <property type="term" value="P:pexophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903044">
        <property type="term" value="P:protein localization to membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034497">
        <property type="term" value="P:protein localization to phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031503">
        <property type="term" value="P:protein-containing complex localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034517">
        <property type="term" value="P:ribophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000011">
        <property type="term" value="P:vacuole inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000243">
        <property type="entry name" value="Putative Vacuolar protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000095">
        <property type="entry name" value="Vacuolar protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="7" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0926">Vacuole</keyword>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="87"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="128"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="169"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="210"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
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        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
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        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
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            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024821"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU369097"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA47479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="559" mass="60142" checksum="E6C1C5F242F06AFD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHE9</accession>
    <name>G4NHE9_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720026.1">
        <property type="nucleotide sequence ID" value="XM_003719978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHE9"/>
    <dbReference type="GeneID" id="2677266"/>
    <dbReference type="KEGG" id="mgr:MGG_03865"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03865"/>
    <dbReference type="eggNOG" id="ENOG502RJKU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_188547_2_0_1"/>
    <dbReference type="InParanoid" id="G4NHE9"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466341" evidence="1">
        <location>
            <begin position="18"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="73" mass="7529" checksum="C9DBA915853409F7" modified="2011-12-14" version="1">MQYSFVTLFALVAAVSALATPQQQHNEFVKRQAAGAAQGGGVAVNAPAMTNAQGEVIAFDSTKVYKDATAKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHG2</accession>
    <name>G4NHG2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    </reference>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="353" mass="37620" checksum="DE6BB7CD0C252332" modified="2011-12-14" version="1">MATLKPPTAPLAASTSPKRKRDQLSLDSRPHTPALQNQTSNFSFELPAKDCEDGNSSPRSKVARKFQGLALGVVATDSGAGTLASSSQPPDADSTSGAAKRSAIESFGSSKEMHYVSVEGHADDGSAMRKRLKLPDATETTPRKHDAVLAGASLTHTSSVFTPILDKSPENQANSPARDSGTTDLKIAGLSGGKVAQSKTGSGISVFKGRRQQAGPPLVAAKTNGDGNATEDSDMEVVDPVRAALTWHEDEITVYDPNDEDDDGVGINGIGFRPTPAIAHARSMKRRQQLAEYKKREEREARARRTLRRRTSPKSGSEAAQVPDGDANPTQSPEPPARRVRFTEFEPTVVITT</sequence>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    </feature>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="439" mass="46455" checksum="1E3B33E0E5E68CA3" modified="2011-12-14" version="1">MDDQFNVRTDDDLFLDDFEPVDSEAVPSVVAPEPQTPIEHSPSVPETRPTTSEARPQNPTPRKAASTRPPPSTNTEPRPRGQLGQSRHAPAASSPNTRGGRGQRGRGGGGIGKPHAQAVQQANKPEPAEASTPAAAPEDSSDAVEGATPSAPADEDPNAPPPNAPTGPAAATAAAGQQTPVKPASVTSEARLKSGANPRTKLTDEELSAKMAAMAVASAEKMRRHNQAQRDERDHEMAMARSAEDARKRRAAEQEKRRQAEEDRQRLEDERAKNRERKLKAMGAKDGAWEQEAQQEDRRAFTGGANGGIRGSKGLHSGRLGGLQGSKYATGDGDDAPEDRGYHNHRGGRGGGRGRGRGGDFGGRGGDRNGQQASKPAINNEAEFPPLSTNAAPKTAAVEAVKKSETPVKMFSPLAPNARWDDEVEAEDARTKAEDKPAA</sequence>
</entry>
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    <accession>G4NHR5</accession>
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            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
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                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="226" mass="24959" checksum="A9BCF971511485FC" modified="2011-12-14" version="1">MNPFYFILCFITLVSSVAVNPAHHENNLEARTSSGRGSTAQDATLGIPPPLNVDPKRVQVWIRLDKTIPTEDFYKNDQGFTHTALKNLIREAGGQHTDVVVGNKDKWIEYGMFFERGPWADSAESALGYPTRVRVYDLKPKQNVKWTYVGLLDASIKSPVDPILLEEARKLGGHSYSTETWNCSVNAMSRAVMQPLFSLLGHPSGGRISNAAGTTVTFPQIGSPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHX6</accession>
    <name>G4NHX6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720203.1">
        <property type="nucleotide sequence ID" value="XM_003720155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHX6"/>
    <dbReference type="SMR" id="G4NHX6"/>
    <dbReference type="STRING" id="242507.G4NHX6"/>
    <dbReference type="GeneID" id="12987217"/>
    <dbReference type="KEGG" id="mgr:MGG_17787"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17787"/>
    <dbReference type="eggNOG" id="KOG1947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_479857_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHX6"/>
    <dbReference type="OMA" id="DISECPH"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF95">
        <property type="entry name" value="F-BOX PROTEIN YLR352W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="58"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="568" mass="61881" checksum="38A886729EAE5E2D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI74</accession>
    <name>G4NI74_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_17812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720301.1">
        <property type="nucleotide sequence ID" value="XM_003720253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI74"/>
    <dbReference type="SMR" id="G4NI74"/>
    <dbReference type="STRING" id="242507.G4NI74"/>
    <dbReference type="GeneID" id="12987279"/>
    <dbReference type="KEGG" id="mgr:MGG_17812"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17812"/>
    <dbReference type="eggNOG" id="KOG1198">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_16_5_1"/>
    <dbReference type="InParanoid" id="G4NI74"/>
    <dbReference type="OMA" id="GKEANHQ"/>
    <dbReference type="OrthoDB" id="9992527at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF3">
        <property type="entry name" value="ENOYL REDUCTASE (ER) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="15"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="370" mass="40863" checksum="CD984A351396237A" modified="2011-12-14" version="1">MTSTNRTHAALVTVAPRAPLQIHQRPTQSPRGNEILIRSTFTASTPLDLHRADGGLLVHDAECMGATTVGIVSEVGPDVSRFKPGDEVFGWAFEDQKQRAHQEFVTAPEWLFAHIPEGFSMEQVATVPENLITAFNTVAVDLGLPTPWPKPEGYVPPRAEEPILVWGAASSVGQFTLEVLRFYGYKHILATASPGHHDYLRELGATECFDYRDPGVTEALIEAGKRIRGNTKPTIPMVVDCIGSVSGTLEHISKIAEKGSTVAVMLPVILKTPTQTQAPEYSMEVPGHNKWEDGVNLRGVRTFFVYKNSEFFREKLASEIIPEVLAQGVVRPQRYRVIEGKTMLERGEKALDALRDGVSGEKLVWRTNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIR4</accession>
    <name>G4NIR4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Sulfite reductase [NADPH] subunit beta</fullName>
            <ecNumber evidence="6">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">MGG_04144</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalyzes the reduction of sulfite to sulfide, one of several activities required for the biosynthesis of L-cysteine from sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>hydrogen sulfide + 3 NADP(+) + 3 H2O = sulfite + 3 NADPH + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="19">Alpha(2)-beta(2). The alpha component is a flavoprotein, the beta component is a hemoprotein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="6"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719686.1">
        <property type="nucleotide sequence ID" value="XM_003719638.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NIR4"/>
    <dbReference type="FunCoup" id="G4NIR4">
        <property type="interactions" value="29"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NIR4"/>
    <dbReference type="GeneID" id="2677654"/>
    <dbReference type="KEGG" id="mgr:MGG_04144"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04144"/>
    <dbReference type="eggNOG" id="KOG0560">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001975_1_0_1"/>
    <dbReference type="InParanoid" id="G4NIR4"/>
    <dbReference type="OMA" id="YGSYTQV"/>
    <dbReference type="OrthoDB" id="1688044at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009337">
        <property type="term" value="C:sulfite reductase complex (NADPH)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050311">
        <property type="term" value="F:sulfite reductase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000007">
        <property type="entry name" value="Pyruvate:ferredoxin (Flavodoxin) oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000003">
        <property type="entry name" value="Sulfite reductase [NADPH] hemoprotein beta-component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000004">
        <property type="entry name" value="Sulfite reductase [NADPH] hemoprotein beta-component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000051">
        <property type="entry name" value="Sulfite reductase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.480.20:FF:000012">
        <property type="entry name" value="Sulfite reductase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000016">
        <property type="entry name" value="Sulfite reductase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.480.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.480.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein,Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01540">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011786">
        <property type="entry name" value="CysI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02041">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010029">
        <property type="entry name" value="PRK13504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493:SF47">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="Nitrite and sulphite reductase 4Fe-4S domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="Nitrite/Sulfite reductase N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="22">
        <location>
            <begin position="794"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="251"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00052219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00057613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00063391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00067595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="EHA47319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1533" mass="169188" checksum="57FFBD2728210A06" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJ26</accession>
    <name>G4NJ26_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_02763</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix. Essential for the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing. It also suppresses a variety of mitochondrial intron mutations and its absence may disturb the assembly of mitochondrial membrane complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homopentamer. Forms homooligomers. Interacts with MFM1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Mitochondrion inner membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720985.1">
        <property type="nucleotide sequence ID" value="XM_003720937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJ26"/>
    <dbReference type="SMR" id="G4NJ26"/>
    <dbReference type="FunCoup" id="G4NJ26">
        <property type="interactions" value="319"/>
    </dbReference>
    <dbReference type="GeneID" id="2682768"/>
    <dbReference type="KEGG" id="mgr:MGG_02763"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02763"/>
    <dbReference type="eggNOG" id="KOG2662">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025144_2_0_1"/>
    <dbReference type="InParanoid" id="G4NJ26"/>
    <dbReference type="OMA" id="TSSWFRE"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045016">
        <property type="term" value="P:mitochondrial magnesium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000005">
        <property type="entry name" value="Inner membrane magnesium transporter MRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.128.330:FF:000002">
        <property type="entry name" value="Inner membrane magnesium transporter mrs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF0">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 14" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00046105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU366042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA46242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="557" mass="62237" checksum="DCEE61F0FEDD71C2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJJ2</accession>
    <name>G4NJJ2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Coatomer subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_02634</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Oligomeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Golgi apparatus membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Cytoplasmic vesicle</location>
            <location evidence="13">COPI-coated vesicle membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the COPG family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721154.1">
        <property type="nucleotide sequence ID" value="XM_003721106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJJ2"/>
    <dbReference type="SMR" id="G4NJJ2"/>
    <dbReference type="FunCoup" id="G4NJJ2">
        <property type="interactions" value="1192"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NJJ2"/>
    <dbReference type="GeneID" id="2682833"/>
    <dbReference type="KEGG" id="mgr:MGG_02634"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02634"/>
    <dbReference type="eggNOG" id="KOG1078">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010353_2_0_1"/>
    <dbReference type="InParanoid" id="G4NJJ2"/>
    <dbReference type="OMA" id="DFIEDCE"/>
    <dbReference type="OrthoDB" id="1074925at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000046">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000071">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1480:FF:000001">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000008">
        <property type="entry name" value="Coatomer subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1480">
        <property type="entry name" value="Coatomer, gamma subunit, appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032154">
        <property type="entry name" value="Coatomer_g_Cpla"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017106">
        <property type="entry name" value="Coatomer_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013040">
        <property type="entry name" value="Coatomer_gsu_app_Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037067">
        <property type="entry name" value="Coatomer_gsu_app_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261:SF0">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16381">
        <property type="entry name" value="Coatomer_g_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08752">
        <property type="entry name" value="COP-gamma_platf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037093">
        <property type="entry name" value="Coatomer_gamma_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 13" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="15">
        <location>
            <begin position="21"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer gamma subunit appendage Ig-like subdomain" evidence="16">
        <location>
            <begin position="651"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer subunit gamma C-terminal" evidence="17">
        <location>
            <begin position="802"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="609"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR037093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA46411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="917" mass="101247" checksum="7043F833EF57CD26" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJT1</accession>
    <name>G4NJT1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720491.1">
        <property type="nucleotide sequence ID" value="XM_003720443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJT1"/>
    <dbReference type="GeneID" id="12987374"/>
    <dbReference type="KEGG" id="mgr:MGG_17850"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17850"/>
    <dbReference type="HOGENOM" id="CLU_2455170_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJT1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA45748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="89" mass="10211" checksum="DBE3B00874E07449" modified="2011-12-14" version="1">MVDYRAANVRMFNWGRMARQQGRKLNQLDANGHVLEADLWGKAAQDWRARTWILLVASITVDRWPRCALNPGDIAGMYSYLVVFGLTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJV6</accession>
    <name>G4NJV6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-1,3-glucan-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02573</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721228.1">
        <property type="nucleotide sequence ID" value="XM_003721180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJV6"/>
    <dbReference type="SMR" id="G4NJV6"/>
    <dbReference type="STRING" id="242507.G4NJV6"/>
    <dbReference type="GeneID" id="2682743"/>
    <dbReference type="KEGG" id="mgr:MGG_02573"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02573"/>
    <dbReference type="eggNOG" id="ENOG502QRX5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019533_1_2_1"/>
    <dbReference type="InParanoid" id="G4NJV6"/>
    <dbReference type="OMA" id="VWSQTGR"/>
    <dbReference type="OrthoDB" id="4781at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000178">
        <property type="entry name" value="Glycoside hydrolase family 16 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF62">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="153"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="504" mass="56533" checksum="2DD4B516D66C828B" modified="2011-12-14" version="1">MDQERPYNGNYSSRTGSRANHRTSETPTSPNDIMTPHRASTPESPYLTATPGAASSSNPFGDGIESRASHRSSAGGHNPFGTPAMSRPASSYESGSGIGNRFEERAQRYFHSRRVRKGEVEKPWLEKRHPKEKWVTILPIIGILVGLGISGVLVWDGIRSVVKHNYCMVLDENFSGGLRDDVWTKEVTVGGFGNGEFQETTGTDENVFVEDGVLKIKATLQDETKIQQDTVIDLIKDGTCTSTLVQDCIAATNTTVGNATIVPPTRSARIHTKKGATIKYGRVEVSARMPEGDWLWPAIWMMPVDDVYGPWPRSGEIDIAESRGNDWRYAQGGNNIASSALHWGPNAANNAWWRTNNKRQALKSTYSSDFNTFGLEWSQNYLFTYINSRLLQVMYVNFDQPLYKRGNFPEAGANGTRLQDPWTQTGRSQTPFDQRFFLILNLAVGGTNGWFEDGKSGKPWLNGSPNAKKDFWEARDKWFPTWKRPQMEIRSVKMWQQCNGNEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL93</accession>
    <name>G4NL93_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721481.1">
        <property type="nucleotide sequence ID" value="XM_003721433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL93"/>
    <dbReference type="GeneID" id="5051413"/>
    <dbReference type="KEGG" id="mgr:MGG_14053"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14053"/>
    <dbReference type="HOGENOM" id="CLU_2400110_0_0_1"/>
    <dbReference type="InParanoid" id="G4NL93"/>
    <dbReference type="OrthoDB" id="10444430at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466740" evidence="1">
        <location>
            <begin position="18"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="93" mass="9853" checksum="0C7E60A06D835401" modified="2011-12-14" version="1">MRFTTSVLATLIAVVAAAPAPEAASVDSNVQLATSLVQVLDPDLPFMLASEKLKAQGCRDEKTFLQCLLNGCPPIIPPGGCISEITCYIIWCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLE8</accession>
    <name>G4NLE8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_09598</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721492.1">
        <property type="nucleotide sequence ID" value="XM_003721444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLE8"/>
    <dbReference type="SMR" id="G4NLE8"/>
    <dbReference type="STRING" id="242507.G4NLE8"/>
    <dbReference type="GeneID" id="2680603"/>
    <dbReference type="KEGG" id="mgr:MGG_09598"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09598"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_31_0_1"/>
    <dbReference type="InParanoid" id="G4NLE8"/>
    <dbReference type="OMA" id="YEFSHAT"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000090">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF87">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALND-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA46749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="574" mass="64305" checksum="E122C3305160AAD7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH02</accession>
    <name>G5EH02_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantothenate-cysteine ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g472</name>
        <name evidence="3" type="ORF">MGG_17982</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721034.1">
        <property type="nucleotide sequence ID" value="XM_003720986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH02"/>
    <dbReference type="SMR" id="G5EH02"/>
    <dbReference type="FunCoup" id="G5EH02">
        <property type="interactions" value="808"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EH02"/>
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    <dbReference type="KEGG" id="mgr:MGG_17982"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17982"/>
    <dbReference type="eggNOG" id="KOG2728">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042326_1_1_1"/>
    <dbReference type="OMA" id="LERYQHH"/>
    <dbReference type="OrthoDB" id="70224at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990181">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pantothenate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="439" mass="48238" checksum="1D3395B75144FC27" modified="2011-12-14" version="1">MSNVPQPPKPAGAEPSAAAEEDHYFSSNPPPRGLSEHVALASAFIEQHAAANRRVVLVTSGGTTVPLERQTVRFIDNFSAGTRGATSAEYFLEAGYAVIFLHRQFSLLPYSRHYSHTPTDCFLDFLHEENGAVVAEPGRAEKMLGVLRKYRAAKQGNMLLMLPFVTITDYLYELRAVAQLMRPLGPRGLLYLAAAVSDFFVPPERMAEHKIQSTTAVERMKHSSSSTERKPQAQAAPPLGALPIVPIPPGEQPLQQPTTLSAEELNTAVAKEQAAADDETFDNFDSSPAVPRSKRLIVDLDPVPKFLKNLVDGWAPQGMIVSFKLETDPAILVHKARYSLDRYQHHLVIGNLLSTRKWEVVFVAPGAADRWIRVPTGRRRGSVSGREDMVGAAEAKMRVAEMPLDPASLPEGEPEMEIESLIIPAVDELHTRHIKSIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH27</accession>
    <name>G5EH27_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGCH7_ch7g333</name>
        <name evidence="5" type="ORF">MGG_02612</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15</strain>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721183.1">
        <property type="nucleotide sequence ID" value="XM_003721135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH27"/>
    <dbReference type="SMR" id="G5EH27"/>
    <dbReference type="GeneID" id="2682811"/>
    <dbReference type="KEGG" id="mgr:MGG_02612"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02612"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="OMA" id="YMTGTDF"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF63">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EAQ70926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA46440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="280" mass="29662" checksum="297C4673A9B274D3" modified="2011-12-14" version="1">MAGRLAGKNAVITGAAGGIGLETSILFAKEGAHVLMADISLDALAKALDKVKSLVPGAQVETVKCDVSKEAEVKAMIEHVDAWGGLDIIFNNAGIMHADDADAVDTPENIWNLTQDINVKGVWYGSKHAVLALRRHKKTKGSIINTASVVALVGSATPQLAYTASKGAVLAMTRELAIVHAREGFRFNNLCPAPLNTPLLQDWLGDDQAKRHRREVHFPTGRFGEAVEQAQAVLFLASDESSFVNGHDFVVDGGMTKAYVTPEGPAMAAPQNNASKSSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHC9</accession>
    <name>G5EHC9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g123</name>
        <name evidence="3" type="ORF">MGG_10574</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721376.1">
        <property type="nucleotide sequence ID" value="XM_003721328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHC9"/>
    <dbReference type="SMR" id="G5EHC9"/>
    <dbReference type="GeneID" id="2682187"/>
    <dbReference type="KEGG" id="mgr:MGG_10574"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10574"/>
    <dbReference type="eggNOG" id="ENOG502SPKC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086503_7_0_1"/>
    <dbReference type="OMA" id="WYGCYVT"/>
    <dbReference type="OrthoDB" id="2744543at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF23">
        <property type="entry name" value="FAMILY N-ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="174" mass="18835" checksum="54B8CFC0CB802FB9" modified="2011-12-14" version="1">MAENTSQTLAPIPSIPAGYAVRTGLPPAPVYRDLRSRAGIIPVTPQQAEAAIKGSWFGCHIVHTSASSEETIVGMGGVIANGSWYFHIVDIAILPEHQRKGLGKLVIHTLMEHILANKAEGRPFICLSASDEGASLYRKCAFMDGEKFGETGMVWEGTYPEIVKELRDAEKAQS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-07-10" modified="2026-01-28" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4R8B5</accession>
    <accession>G4N6P1</accession>
    <name>HAS1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>ATP-dependent RNA helicase HAS1</fullName>
            <ecNumber>3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">HAS1</name>
        <name type="ORF">MGG_06522</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text>ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associates in the nucleolus with the 60S and pre-60S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text>The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717029.1">
        <property type="nucleotide sequence ID" value="XM_003716981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R8B5"/>
    <dbReference type="SMR" id="A4R8B5"/>
    <dbReference type="FunCoup" id="A4R8B5">
        <property type="interactions" value="1152"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4R8B5"/>
    <dbReference type="EnsemblFungi" id="MGG_06522T0">
        <property type="protein sequence ID" value="MGG_06522T0"/>
        <property type="gene ID" value="MGG_06522"/>
    </dbReference>
    <dbReference type="GeneID" id="2684677"/>
    <dbReference type="KEGG" id="mgr:MGG_06522"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06522"/>
    <dbReference type="eggNOG" id="KOG0342">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_26_5_1"/>
    <dbReference type="InParanoid" id="A4R8B5"/>
    <dbReference type="OMA" id="LMEFHSQ"/>
    <dbReference type="OrthoDB" id="10259640at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990417">
        <property type="term" value="P:snoRNA release from pre-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17942">
        <property type="entry name" value="DEADc_DDX18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000379">
        <property type="entry name" value="RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000460">
        <property type="entry name" value="RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044773">
        <property type="entry name" value="DDX18/Has1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <feature type="chain" id="PRO_0000294626" description="ATP-dependent RNA helicase HAS1">
        <location>
            <begin position="1"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="143"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="331"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="558"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEAD box">
        <location>
            <begin position="265"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="156"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="587" mass="65349" checksum="B44A6D0DD71D86C4" modified="2007-07-10" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKC7</accession>
    <name>G4MKC7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709330.1">
        <property type="nucleotide sequence ID" value="XM_003709282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKC7"/>
    <dbReference type="SMR" id="G4MKC7"/>
    <dbReference type="GeneID" id="12984441"/>
    <dbReference type="KEGG" id="mgr:MGG_16141"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16141"/>
    <dbReference type="HOGENOM" id="CLU_2061963_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKC7"/>
    <dbReference type="OrthoDB" id="5232167at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="119" mass="13325" checksum="6F2B2EB38A2AB454" modified="2011-12-14" version="1">MKMKSTIRQHRQHPLISAAIALSAIIVTTLILFWSYGGSFSRYQHQRPYSKYRLAVRPKEGVRHLPRLRQLRAESVRQQQEQQLVPHSTAHAAAADSGFGNQQHDVAGDAVDAVSITPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKY3</accession>
    <name>G4MKY3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-1,6-galactanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_05381</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710230.1">
        <property type="nucleotide sequence ID" value="XM_003710182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKY3"/>
    <dbReference type="SMR" id="G4MKY3"/>
    <dbReference type="STRING" id="242507.G4MKY3"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="GeneID" id="2676193"/>
    <dbReference type="KEGG" id="mgr:MGG_05381"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05381"/>
    <dbReference type="eggNOG" id="ENOG502QUKB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039562_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKY3"/>
    <dbReference type="OMA" id="APCYKCT"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263:SF0">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465328" evidence="6">
        <location>
            <begin position="20"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="7">
        <location>
            <begin position="91"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA57618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="480" mass="53983" checksum="EF1D50C30CC7E4B7" modified="2011-12-14" version="1">MKLSVIITQLALATSHATAQVMSTPEIPLTQARSASHPHRRQQTNNSSGSSGWPFAPFSTRGRDIVDSRGEALTLAGVNWPMSGETMIPEGLEFQSAEEILDRIASVGFNVIRFGYATQMVDEIYERDGEDVPLQVALASLGHANGSRITHEILKHNPGWTTQTTRFELWGDILDAAAERGIYAIPDVHVHKAQWCCSHIDGNAWFGDVHFDVENWKRGLSYVAGWAKAHPNVLGLSLRNELRESWNRTDLYYNWQTLVGNMTAGADAIHAANPDLLITWSGMQYDQDLSALTAGRNLLSAPCYRCTAIRDAGRRQPQVFDLDAHPWSDKLVWELHMYHMSEDQDTGDCDVIEANLYRNGFNALGIDAPAACANETIGLDCEKAVRLTPVIFSEFGYEQNVTTLPNDVLQKCLRGFNTKHKVSWMTWSIAGSYRSRQGRQGFEDTWGLTNYDFSGWRDEELVERWWKPYVVDMKPTRKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML59</accession>
    <name>G4ML59_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709407.1">
        <property type="nucleotide sequence ID" value="XM_003709359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML59"/>
    <dbReference type="GeneID" id="12984468"/>
    <dbReference type="KEGG" id="mgr:MGG_16156"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16156"/>
    <dbReference type="HOGENOM" id="CLU_1907104_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML59"/>
    <dbReference type="OrthoDB" id="10477179at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="133" mass="14602" checksum="E9D88125D6DBA006" modified="2011-12-14" version="1">MDKSQTNIRKGPAAYLEHSTTALARLPEVQLYASSAGFKTLSMQKSGQAGSTPWTMTSQVQKIPSTKKRGGRASHTFHCHGRTDEDGKKGFNRSGSRRFQAPLANKNGSSERKFIHEGLSPLVSVRVGHLFCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLL1</accession>
    <name>G4MLL1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">TFIID subunit TAF5 NTD2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_06742</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat TAF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709456.1">
        <property type="nucleotide sequence ID" value="XM_003709408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLL1"/>
    <dbReference type="SMR" id="G4MLL1"/>
    <dbReference type="FunCoup" id="G4MLL1">
        <property type="interactions" value="760"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MLL1"/>
    <dbReference type="GeneID" id="2684915"/>
    <dbReference type="KEGG" id="mgr:MGG_06742"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06742"/>
    <dbReference type="eggNOG" id="KOG0263">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005884_0_2_1"/>
    <dbReference type="InParanoid" id="G4MLL1"/>
    <dbReference type="OMA" id="HNHPVWD"/>
    <dbReference type="OrthoDB" id="10266330at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08044">
        <property type="entry name" value="TAF5_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="10">
        <location>
            <begin position="94"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="381"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="499"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="541"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="585"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="635"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="672"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="684"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="717"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="729"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA56844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="784" mass="84459" checksum="1FDF4163FAA8971C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMP7</accession>
    <name>G4MMP7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710431.1">
        <property type="nucleotide sequence ID" value="XM_003710383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMP7"/>
    <dbReference type="GeneID" id="12986335"/>
    <dbReference type="KEGG" id="mgr:MGG_15150"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15150"/>
    <dbReference type="eggNOG" id="ENOG502RMNS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144298_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMP7"/>
    <dbReference type="OMA" id="IWENSCH"/>
    <dbReference type="OrthoDB" id="4524829at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="108" mass="12392" checksum="65C94231F04CBDAE" modified="2011-12-14" version="1">MSKVWLNEKPKTVEGHTNTCQLFFEGNPVHENPISCHDNTVDIQTALRKADPRFELRLARKDKTVEGHTRSFNIKCKDEDILKDHSCHDNMITIVNSINALWAVLPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNG6</accession>
    <name>G4MNG6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_16222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family. GNAT subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709692.1">
        <property type="nucleotide sequence ID" value="XM_003709644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNG6"/>
    <dbReference type="SMR" id="G4MNG6"/>
    <dbReference type="STRING" id="242507.G4MNG6"/>
    <dbReference type="GeneID" id="12985241"/>
    <dbReference type="KEGG" id="mgr:MGG_16222"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16222"/>
    <dbReference type="eggNOG" id="KOG4135">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073102_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNG6"/>
    <dbReference type="OMA" id="WHVPRYH"/>
    <dbReference type="OrthoDB" id="5043642at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039135">
        <property type="entry name" value="NAT9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256:SF16">
        <property type="entry name" value="ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13256">
        <property type="entry name" value="N-ACETYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="14"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA57080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="237" mass="26710" checksum="262854E93788EEAA" modified="2011-12-14" version="1">MKFNKDTAISTDQILLVPYDKHHVVTYHRWMEDPAIQEATASEPLTLEEEYENQQSWRDSHDKLTFILCQPAKAEENKMEAGQCDSPDRMIGDINFFLYPWDEGEEDDQQTTNPEKAEYVGEIDVMVADTSQRGKGIGKAAVDAFMHYICCNQKPILQEHHGVTGEPSLRKFMVKIKADNRASIALFRGVGFQQDGDVDYFGEVKMVLDDFGGVASKAVPGFRELTYCRTLALGGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNP1</accession>
    <name>G4MNP1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_02100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708869.1">
        <property type="nucleotide sequence ID" value="XM_003708821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNP1"/>
    <dbReference type="GeneID" id="2681191"/>
    <dbReference type="KEGG" id="mgr:MGG_02100"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02100"/>
    <dbReference type="HOGENOM" id="CLU_2085290_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNP1"/>
    <dbReference type="OMA" id="EKPTIGC"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="117" mass="13435" checksum="20EB2DB768DEE7AE" modified="2011-12-14" version="1">MANAVSAEGSGKEKPTIGCQVRSVVEEVDGIDHTGRKVSSLTYSQPIRLKHPIKHTKFLDGKSAYLELDKDCKRVKMTTRLPNFYFEVQPWYTTYQKWDESGKVPTEIIRARYQVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNS1</accession>
    <name>G4MNS1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_14601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708899.1">
        <property type="nucleotide sequence ID" value="XM_003708851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNS1"/>
    <dbReference type="STRING" id="242507.G4MNS1"/>
    <dbReference type="GeneID" id="5048739"/>
    <dbReference type="KEGG" id="mgr:MGG_14601"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14601"/>
    <dbReference type="eggNOG" id="ENOG502RZSK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008976_2_1_1"/>
    <dbReference type="InParanoid" id="G4MNS1"/>
    <dbReference type="OMA" id="HRTWAGH"/>
    <dbReference type="OrthoDB" id="5238236at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046539">
        <property type="entry name" value="DUF6604"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38795:SF1">
        <property type="entry name" value="DUF6604 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20253">
        <property type="entry name" value="DUF6604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6604" evidence="2">
        <location>
            <begin position="11"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="437" mass="49126" checksum="460774CF36F18FAB" modified="2011-12-14" version="1">MLPSSLTSIYRQYKHDTDVVATWLATTAKHLGYDASKFTLSRQTSSRTQDTKHANLAGKASQTHNESLKIDSSSTHGRRRFVLAIRDFVPLARYIASQPRRVRITSSFSTAIDRAVHARADFHVLLSKYGNITDDTADSRHSHFAGILGAVRDLLRPLTLPSVPVMTGTCRTLGDKKLYYFNSFTPLTVYDTPDMDETVGGNMIAQPVYEAEREDTFEDACWAFSILLHDFTALRMQVKNLWERYARRELHLGSVAIATNAAIQIARSLEEDVEHLFAAHGGAHVIQKQWYGILCDDAGHDSRPEPGELLNWEAYRLADDCFLPANLMIAMFFEAYALGKMHHYNGNFDWYGELAEAIDHKTEFFQGKAALSEILMETAVVFHVLSDKETIHCRDEFSLAILAMLDCTRPSVPLSLSLAGTMYLDSLVILKGQLDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPC2</accession>
    <name>G4MPC2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709787.1">
        <property type="nucleotide sequence ID" value="XM_003709739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPC2"/>
    <dbReference type="GeneID" id="2680243"/>
    <dbReference type="KEGG" id="mgr:MGG_09176"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09176"/>
    <dbReference type="HOGENOM" id="CLU_1294628_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPC2"/>
    <dbReference type="OrthoDB" id="5244131at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="213" mass="23532" checksum="D8F230948774A268" modified="2011-12-14" version="1">MTEPNIPHFQPLTVSGQFPESDVRGAAAREAASGRVTYLDWEEQQRLEQEEQQLRNELDALKSEVQVKRQLRRYMRIFDAATAGDRMITDVAEKARRCRQSFDIVGLMIKVCSVTDFVVKEIQNERYAPTPVASPLTEAASIPGSPSRIEQTPISSHAATYGSSPSPGSRGSPQPAESIHIVSTEPVAEMTKPATSGPIVTRYGRIIRAPKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPJ9</accession>
    <name>G4MPJ9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710654.1">
        <property type="nucleotide sequence ID" value="XM_003710606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPJ9"/>
    <dbReference type="SMR" id="G4MPJ9"/>
    <dbReference type="GeneID" id="12986401"/>
    <dbReference type="KEGG" id="mgr:MGG_15168"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15168"/>
    <dbReference type="HOGENOM" id="CLU_704136_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPJ9"/>
    <dbReference type="OrthoDB" id="10359884at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="392" mass="42939" checksum="DF75626053AA350B" modified="2011-12-14" version="1">MARSLRHKQWSEEDIELIYLNRRLRDCKSKSKGSSGSGGGGFNIICEGCIAQMLGLWYAYQKCRLPASEVASMLTPERLAELRHTHAADMAAIERETLEAMGGHDPPSLDCHLLRLWTGILPDHDDDPSLLRAKLMFVMRGSKYGLYDLVDGPKLKEWLQAMEQLQKHRVHELEQLEALRRRSNRSANSGSGSGSGSGSSSGSSSITSRSKTWSSCRCRYQDMGSLTPRGFWDFVKPRLHVSIGNAIESHYFANNNAHPVCAADVYITMAYAPLQADLEKMARTHRAELAVRDRLSMEMRLVEEAFRGLGRGRGSASVVEASAGGSSSSGGGDGGSNASKKSWVSAEDAEREAVRLAYERDSYGLGPLARAYTARQAARDAFARSGGRGSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPR7</accession>
    <name>G4MPR7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_11764</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709827.1">
        <property type="nucleotide sequence ID" value="XM_003709779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPR7"/>
    <dbReference type="STRING" id="242507.G4MPR7"/>
    <dbReference type="GeneID" id="5049553"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11764"/>
    <dbReference type="eggNOG" id="ENOG502R6NR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4MPR7"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="PHI-base" id="PHI:5652"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052400">
        <property type="entry name" value="Zn2-C6_fungal_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN ECM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47657:SF12">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="663" mass="73567" checksum="635AA2129BDD85A7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR44</accession>
    <name>G4MR44_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709988.1">
        <property type="nucleotide sequence ID" value="XM_003709940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR44"/>
    <dbReference type="SMR" id="G4MR44"/>
    <dbReference type="FunCoup" id="G4MR44">
        <property type="interactions" value="881"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MR44"/>
    <dbReference type="GeneID" id="2680938"/>
    <dbReference type="KEGG" id="mgr:MGG_09894"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09894"/>
    <dbReference type="eggNOG" id="KOG3502">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_178987_1_0_1"/>
    <dbReference type="InParanoid" id="G4MR44"/>
    <dbReference type="OMA" id="NTGMHGE"/>
    <dbReference type="OrthoDB" id="10258930at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000025">
        <property type="entry name" value="40S ribosomal protein S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00292">
        <property type="entry name" value="Ribosomal_eS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="68" mass="7718" checksum="51E5D1E5D45768C8" modified="2011-12-14" version="1">MDASKQPVKLVKVTRVLGRTGSRGGVTQVRVEFMDDQSRSIIRNVKGPVRVDDILVLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR71</accession>
    <name>G4MR71_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA topoisomerase I</fullName>
            <ecNumber evidence="7">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA topoisomerase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_09917</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="7"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710015.1">
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        <property type="taxonomic scope" value="Eukaryota"/>
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        <source>
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    <sequence length="906" mass="102544" checksum="ADEC93C05CC4D5EB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRA2</accession>
    <name>G4MRA2_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04692</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710839.1">
        <property type="nucleotide sequence ID" value="XM_003710791.1"/>
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    <dbReference type="eggNOG" id="ENOG502S8TD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032674_0_0_1"/>
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    <dbReference type="OrthoDB" id="5417811at2759"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="494" mass="56036" checksum="D51A36010CCEFCF7" modified="2011-12-14" version="1">MSFSMRNWMRSSTVIAPAPEQAVGDVEPQQEPSRPQPQPQPHPTSPMPPSQQPEMEERRGANAPGRWRFSRSTIPSFFGGRRDSQQGLPHHQQQQQAEMPRPTSSHYSEVESPKSPHFALGMPPLPSTRLHLPNLARTWSHGTNGPPSRPGTSRAPMPPLIQVHGVDNRPPSLVDGPMFPEVASPRAAHIPQRPRRSEETSSGESTDQAAEPGHERRRHRHHHRRENETEEERRQRRRERHRRRRARERREARPTPKHFLGCFPYPQSKHVRTQLLKCFVSGTFLVALLITYLALFLTKNMATSEFTVLLVLIMLFTAVIFLHGMVRLCLYMLKTPAGRREHDERLSAEEHSILRRNRAAMRQAYAPGGYAIPEQPIRVVLARDEEAAGIESETTKYKPPAYGLWRESVRVDPDRIYWQRNEHPALRGGGESSSEEEAGTTGVRRPPSYASDDGVSYVVEARPRSMAPTTDVPLPPHPSEAGRVGTPPLPNQRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRM8</accession>
    <name>G4MRM8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable 26S proteasome regulatory subunit p27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_09953</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p27 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710063.1">
        <property type="nucleotide sequence ID" value="XM_003710015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRM8"/>
    <dbReference type="SMR" id="G4MRM8"/>
    <dbReference type="FunCoup" id="G4MRM8">
        <property type="interactions" value="1091"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRM8"/>
    <dbReference type="GeneID" id="2680923"/>
    <dbReference type="KEGG" id="mgr:MGG_09953"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09953"/>
    <dbReference type="eggNOG" id="KOG3129">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073146_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRM8"/>
    <dbReference type="OMA" id="DWGGRGM"/>
    <dbReference type="OrthoDB" id="72325at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000107">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040815">
        <property type="entry name" value="Nas2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035269">
        <property type="entry name" value="PSMD9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18265">
        <property type="entry name" value="Nas2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nas2 N-terminal" evidence="6">
        <location>
            <begin position="29"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="144"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00068021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA57451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="232" mass="25438" checksum="548E5FFE3DFF946B" modified="2011-12-14" version="1">MDSLHAPTIPSGPTTAPTANGRAGHLTIAELQRKKDDLEAELRALGGVLESHNVDMNTNLLTPDGFPRADIDVPQIRTTRARIIHLRNDYKDLMATIEKQLHEHFASLNDEEEEDITANRQQEQQASQLTDSVPETLELPFAKVNSVVDNSPADSAGLKAGDLVRNFGYVNRTNHDGLKKVAECVQGNEGQTILVKVSRSTGSGQTQELQLSIRPRRDWGGRGLLGCHIIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRT6</accession>
    <name>G4MRT6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TPR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710913.1">
        <property type="nucleotide sequence ID" value="XM_003710865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRT6"/>
    <dbReference type="SMR" id="G4MRT6"/>
    <dbReference type="FunCoup" id="G4MRT6">
        <property type="interactions" value="271"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRT6"/>
    <dbReference type="GeneID" id="2677928"/>
    <dbReference type="KEGG" id="mgr:MGG_04565"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04565"/>
    <dbReference type="eggNOG" id="ENOG502QSAH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040959_2_1_1"/>
    <dbReference type="InParanoid" id="G4MRT6"/>
    <dbReference type="OMA" id="ETYMTDL"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd24142">
        <property type="entry name" value="ACL4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="392" mass="43176" checksum="4FA7FF57E0227F6A" modified="2011-12-14" version="1">MAPTRPHNKKARSRQKNRSGADSANNARRTKQLLAEATALLEQGDVTSALRTAKDAVEAAPERLEAEARTLLGEVLLEVGDGEAARTQLLQAAEVDVEEDAGGVNLGARAEKYLWLAQLSEDGGADSVRWLERGAGVLRAALARVEERAVAAGLTDRQKTLVDEARRDLNRRLSSALCAVAEVYMTDLSWETDAEQRCEALITEATMLAPDLADAWQTVANVRISQGKPDEARTALTRSMDPWWSGEDDAAVPPFPTRVSLVRLLLEVEWEDRAIEVTERLIKEDDSSVEVLYLGGFGQFLIGEKLKAAAKDGVEDDWKTIWASARRWLKQCLTLFAAQEYEDDRLGQHAQELLGTLNKELGEAADDDDDDEDDGWEDDEDDEEGDGDKVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS77</accession>
    <name>G4MS77_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase Rpb4/RPC9 core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_04508</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710947.1">
        <property type="nucleotide sequence ID" value="XM_003710899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS77"/>
    <dbReference type="SMR" id="G4MS77"/>
    <dbReference type="STRING" id="242507.G4MS77"/>
    <dbReference type="GeneID" id="2678078"/>
    <dbReference type="KEGG" id="mgr:MGG_04508"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04508"/>
    <dbReference type="eggNOG" id="KOG2351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110332_0_0_1"/>
    <dbReference type="InParanoid" id="G4MS77"/>
    <dbReference type="OMA" id="HRKTQNE"/>
    <dbReference type="OrthoDB" id="2186918at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030880">
        <property type="term" value="C:RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="5">
        <location>
            <begin position="35"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA58335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="150" mass="17260" checksum="5CE350633CECCB87" modified="2011-12-14" version="1">MPPKKQSGPAVPKMISRPKPPPPGEEIASDEIQLGEFEGVETLSYSEAELVLEALEKKRRKEKRYHETEVLQKTRDHLSLFRRFKTPENVQAAERLLSARPELHKFERAQIASLVPENSDEAKKLIPSLKDKFDDHDLEDLLQELSKFCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSF9</accession>
    <name>G4MSF9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Post-GPI attachment to proteins factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_04527</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the lipid remodeling steps of GPI-anchor maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PGAP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713578.1">
        <property type="nucleotide sequence ID" value="XM_003713530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSF9"/>
    <dbReference type="FunCoup" id="G4MSF9">
        <property type="interactions" value="175"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSF9"/>
    <dbReference type="GeneID" id="2677823"/>
    <dbReference type="KEGG" id="mgr:MGG_04527"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04527"/>
    <dbReference type="eggNOG" id="KOG2970">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032917_1_1_1"/>
    <dbReference type="InParanoid" id="G4MSF9"/>
    <dbReference type="OMA" id="DFMIEDC"/>
    <dbReference type="OrthoDB" id="419770at2759"/>
    <dbReference type="PHI-base" id="PHI:8754"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007217">
        <property type="entry name" value="Per1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148">
        <property type="entry name" value="PER1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148:SF0">
        <property type="entry name" value="POST-GPI ATTACHMENT TO PROTEINS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04080">
        <property type="entry name" value="Per1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 7" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016480367" description="Post-GPI attachment to proteins factor 3" evidence="7">
        <location>
            <begin position="36"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA53771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="358" mass="40099" checksum="F650C0CEE9DA2CD6" modified="2011-12-14" version="1">MIVTQGRRPGAMQHGVRSILPLVLTACLFLGAANASVGDRLPEFRECVQVCLHENCEAGTLAHKVETPLINRLLLWTCPAECDYTCQHIITSDRIESGQPVVQFHGKWPFYRVLGMQEPFSVIFSAGNLYAHLLGFRWLRRHIPESYPLRKYYVGFSFAGVASWLFSIIFHTRDTRATEQLDYFAAGASVLYGLYLAVIRIFRLDRPGSTDGGKTPTGTASSSSSISSSTPRAIRLWTAACLVAYGCHVAYLKLVRWDYGYNMAANVCVGLAQNVLWSAFSYRKYTREGRTWATYPGLAVAWIMLAMSLELFDFPPLWGALDAHALWHLGTIAPAVLWYSFLVKDAQDDMASAERFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT09</accession>
    <name>G4MT09_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_01504</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Regulates also the sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Golgi apparatus membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ARV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714475.1">
        <property type="nucleotide sequence ID" value="XM_003714427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT09"/>
    <dbReference type="FunCoup" id="G4MT09">
        <property type="interactions" value="26"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MT09"/>
    <dbReference type="GeneID" id="2679268"/>
    <dbReference type="KEGG" id="mgr:MGG_01504"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01504"/>
    <dbReference type="eggNOG" id="KOG3134">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057366_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT09"/>
    <dbReference type="OMA" id="MLDMNVK"/>
    <dbReference type="OrthoDB" id="2192830at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097036">
        <property type="term" value="P:regulation of plasma membrane sterol distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467">
        <property type="entry name" value="ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467:SF0">
        <property type="entry name" value="PROTEIN ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA54668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="290" mass="31942" checksum="8F539438C2F2BAA7" modified="2011-12-14" version="1">MPICIECRHPVKTLWTKYSGTGDGDKVSGHNIRLTVCKNCGRFCDKYVEHDFVVLFVDLVLIKPQVYRHLLHNSLMRDGDRFDPTMIRLGILLLLFDVYLTWARIEKQFNTSSSADQSSFSRIAQQPIVLQYMFFLLLCTLSNLAFHLSIRLLTSSPWSPLVLLGLLPAPFERPNSVSTALLVSSSTKLFPILMVIWNYDVPAAARSLGWAVVANNVEALMILLDCGYGAAALLTTAGALSRWAISSAFLTAAGLEGVSVAAETSIAEDGRALWAFLLTANEWAGRLATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT25</accession>
    <name>G4MT25_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nitrogen assimilation transcription factor nit-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_01518</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714491.1">
        <property type="nucleotide sequence ID" value="XM_003714443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT25"/>
    <dbReference type="FunCoup" id="G4MT25">
        <property type="interactions" value="203"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MT25"/>
    <dbReference type="GeneID" id="2679161"/>
    <dbReference type="KEGG" id="mgr:MGG_01518"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01518"/>
    <dbReference type="eggNOG" id="ENOG502QW0K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007003_6_0_1"/>
    <dbReference type="InParanoid" id="G4MT25"/>
    <dbReference type="OMA" id="YIAHTAC"/>
    <dbReference type="OrthoDB" id="2162761at2759"/>
    <dbReference type="PHI-base" id="PHI:5591"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="67"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="684"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="828"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="684"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="708"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="727"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="871"/>
            <end position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="988" mass="108936" checksum="48715235E090852F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU05</accession>
    <name>G4MU05_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_07202</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>propanoyl-CoA + oxaloacetate + H2O = (2S,3S)-2-methylcitrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23780"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:58853"/>
            <dbReference type="EC" id="2.3.3.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715412.1">
        <property type="nucleotide sequence ID" value="XM_003715364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU05"/>
    <dbReference type="SMR" id="G4MU05"/>
    <dbReference type="FunCoup" id="G4MU05">
        <property type="interactions" value="959"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MU05"/>
    <dbReference type="GeneID" id="2683090"/>
    <dbReference type="KEGG" id="mgr:MGG_07202"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07202"/>
    <dbReference type="eggNOG" id="KOG2617">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022049_2_1_1"/>
    <dbReference type="InParanoid" id="G4MU05"/>
    <dbReference type="OMA" id="VLEWLFK"/>
    <dbReference type="OrthoDB" id="8017587at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050440">
        <property type="term" value="F:2-methylcitrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06105">
        <property type="entry name" value="ScCit1-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR610109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA55605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="473" mass="52257" checksum="AF6B27A7CBC12E28" modified="2011-12-14" version="1">MASAMRLSSAFRATARAPAFTARRTAFNGMRCYSAKTQTLKERFAELLPEKIEEIKSLRKEHGSKVIDKVTLDQVYGGARGIKCLVWEGSVLDSEEGIRFRGKTIPECQELLPKAPGGKEPLPEGLFWLLLTGEVPSEAQVRALSAEWAARSDLPKFVEELIDRCPNDLHPMAQFSMAITALEQTSSFAKAYAKGINKKEYWGYTFEDSMDLIAKLPTIAARIYQNVFKGGKVAPVQKDKDYSFNFANQLGFGNNSDFVELLRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSLAAGMNGLAGPLHGLANQEVLNWLTEMKKSVGDDLSDKSITDYLWSTLNSGRVVPGYGHAVLRKTDPRYTAQRVFAQEKMPNDPMFKLVSQVYKIAPGVLTEHGKTKNPFPNVDAHSGVLLQYYGLTEANYYTVLFGVSRAIGVLPQLIIDRAVGAPIERPKSFSTEKWIEIAKKTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUQ8</accession>
    <name>G4MUQ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WW domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713838.1">
        <property type="nucleotide sequence ID" value="XM_003713790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUQ8"/>
    <dbReference type="SMR" id="G4MUQ8"/>
    <dbReference type="STRING" id="242507.G4MUQ8"/>
    <dbReference type="GeneID" id="2679808"/>
    <dbReference type="KEGG" id="mgr:MGG_08822"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08822"/>
    <dbReference type="eggNOG" id="ENOG502RXNF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061843_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUQ8"/>
    <dbReference type="OMA" id="DCQWDPN"/>
    <dbReference type="OrthoDB" id="2444812at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="131"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="319" mass="34448" checksum="78C9116BB506DC71" modified="2011-12-14" version="1">MATTPTENTSDTATGTVATVDQVGIPQSDHDRLGNRESENQPTLSTQVSEEERLDDTKESAVTETAESSGPSANSAAKVAASSSSPTDSPHAEPESDSREDSKDPVGEDGASSSQAPGELQPQLPNEPLPETEDDGWTYQWDPTHQAYYFLNRFTGQTTWENPRQTVAVASSSTADPTPVPPPLPTVAGGYNPAIHGDYDDWVAEQKKAGQLPGDGDAAENVHPPDPATAALFASGAQFNRLTGQYQRPGVGPENHSDDAKSRRQMNAFFDVDAAANSHDGRSLKAERAGKRLTKGELKHFKEKRKARKEEKRRAWLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUQ9</accession>
    <name>G4MUQ9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08823</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713839.1">
        <property type="nucleotide sequence ID" value="XM_003713791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUQ9"/>
    <dbReference type="SMR" id="G4MUQ9"/>
    <dbReference type="CAZy" id="GH16">
        <property type="family name" value="Glycoside Hydrolase Family 16"/>
    </dbReference>
    <dbReference type="GeneID" id="2679809"/>
    <dbReference type="KEGG" id="mgr:MGG_08823"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08823"/>
    <dbReference type="eggNOG" id="ENOG502S0II">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039765_0_1_1"/>
    <dbReference type="InParanoid" id="G4MUQ9"/>
    <dbReference type="OMA" id="WSTHRLD"/>
    <dbReference type="OrthoDB" id="4388755at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00413">
        <property type="entry name" value="Glyco_hydrolase_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38121:SF4">
        <property type="entry name" value="GH16 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465353" description="GH16 domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="68"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="403" mass="43515" checksum="D43304C97FA5CB5C" modified="2011-12-14" version="1">MNLRTVTGSASSILLILSSIHVAVADLPLVSDSKCGCYVTNGSNSAFFTSHRFYDFRSLSQYVGSGIPDAPSSSPQAASNASITSGYFNTSAFTDDWSIMTWNNSASVGGDAAILMVNSPTNLFIQKNNDTDADSDTYLTMRTARNEDFQSASEIESNSNRYRFVSMRMLARTTGAPGACTALFTYRSAKDYADVQEADIEVLTKDPTDKIMYTNQPSYVKVGNDTQNIPESNINGTAPVDWTQWSVHRLDWTPLRTTWYVDGRQVASISFQTPRDASRINLNSWSDGGDWTGLMDVGKEARMQIKWLEMVFNQTSSGTSRMRPRDHTGNSGRGSGNGNSGGASDSGSTEGLSDGKCRTVCSIDDTDQRGMAAVVADGGAATLKLAAWIPISVALVTMAASMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV62</accession>
    <name>G4MV62_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-splicing factor cwc15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_08861</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713884.1">
        <property type="nucleotide sequence ID" value="XM_003713836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV62"/>
    <dbReference type="SMR" id="G4MV62"/>
    <dbReference type="STRING" id="242507.G4MV62"/>
    <dbReference type="GeneID" id="2679847"/>
    <dbReference type="KEGG" id="mgr:MGG_08861"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08861"/>
    <dbReference type="eggNOG" id="KOG3228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068312_0_1_1"/>
    <dbReference type="InParanoid" id="G4MV62"/>
    <dbReference type="OMA" id="KYREHGQ"/>
    <dbReference type="OrthoDB" id="30179at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="156"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA54077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="28010" checksum="B12FE07F3B35DF4D" modified="2011-12-14" version="1">MTTAHRPTFDPAKGKEALRGPAYHQRLLPAHTQLKYRKRGQGGAADADGAIDLRAELLAAEAAHASKSGNSSASIAAPSSKHSPAPNSDDEGAARQKRPLDMTTDGEEDPEAKRRRILAETRELDADDTGGSSEEEDDDDDDSDGDSDDSDDEDAELARELEKIRRERAEKREREEREKAAAAEEERERDIALGNPLLNKPDFNIKRRWDDDVVFKNQARGTEDKGKRKEFINDLLRSDFHKRFMGKYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVW8</accession>
    <name>G4MVW8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715643.1">
        <property type="nucleotide sequence ID" value="XM_003715595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVW8"/>
    <dbReference type="STRING" id="242507.G4MVW8"/>
    <dbReference type="GeneID" id="2678579"/>
    <dbReference type="KEGG" id="mgr:MGG_08414"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08414"/>
    <dbReference type="HOGENOM" id="CLU_1993059_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVW8"/>
    <dbReference type="OrthoDB" id="5228662at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465580" evidence="1">
        <location>
            <begin position="23"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="125" mass="13786" checksum="9BB08B522D3362B5" modified="2011-12-14" version="1">MQTQSLLAAATALALLSDVALAWTEKCIITIRKNDPALGKHTLYDMVSLPPDSDYTFGKFPPATAGVTIGVDDTCRAGLVVGDLNPPYDYRGMENPFYGLTGVELVRQLHDWRENPENVINFSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWA3</accession>
    <name>G4MWA3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714870.1">
        <property type="nucleotide sequence ID" value="XM_003714822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWA3"/>
    <dbReference type="GeneID" id="2679658"/>
    <dbReference type="KEGG" id="mgr:MGG_01850"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01850"/>
    <dbReference type="eggNOG" id="ENOG502T4JW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_829171_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWA3"/>
    <dbReference type="OMA" id="HPMFRGW"/>
    <dbReference type="OrthoDB" id="5222624at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="335" mass="36328" checksum="06B698B79363EDF6" modified="2011-12-14" version="1">MIVRVPGLLGDLGRRDVANPISKPPSASGSPSVATTDAAATDTESFSQDFRPLIVVSSIMGAAVLVMAIITACIMVRRSRKRRSQATAEYTAARQRDPNLSWQEYERRCKLSNSTMFLEAESQRALMISKSLKSRPSLDRPELAEDAVITDPGLPPSPPTPTKASLWTRGRRHASGPEALAMNDSDMEDKEMLLSPSQKPQFKTSPERPGSSGSAGSLRSPVHSSSNSSRRWVWELPDGKKCPPAWANSNARWSGDLRDAPPPVPPPSIRARTPPIWAHPAFRPEGSGMGIVARSYTNDTGLLPSERIKEKPASLNNDTGLLPAEKIKEKPAPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWM4</accession>
    <name>G4MWM4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Prostacyclin synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_01865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714886.1">
        <property type="nucleotide sequence ID" value="XM_003714838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWM4"/>
    <dbReference type="SMR" id="G4MWM4"/>
    <dbReference type="STRING" id="242507.G4MWM4"/>
    <dbReference type="GeneID" id="2679255"/>
    <dbReference type="KEGG" id="mgr:MGG_01865"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01865"/>
    <dbReference type="eggNOG" id="KOG0684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018012_4_2_1"/>
    <dbReference type="InParanoid" id="G4MWM4"/>
    <dbReference type="OMA" id="LVQSAYC"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11040">
        <property type="entry name" value="CYP7_CYP8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053007">
        <property type="entry name" value="CYP450_monoxygenase_sec-met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47582:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA55079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="58354" checksum="AD7FE96B3E4864F2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWR3</accession>
    <name>G4MWR3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Coiled-coil domain-containing protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_08340</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715724.1">
        <property type="nucleotide sequence ID" value="XM_003715676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWR3"/>
    <dbReference type="SMR" id="G4MWR3"/>
    <dbReference type="STRING" id="242507.G4MWR3"/>
    <dbReference type="GeneID" id="2678533"/>
    <dbReference type="KEGG" id="mgr:MGG_08340"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08340"/>
    <dbReference type="eggNOG" id="ENOG502S9DW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041821_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWR3"/>
    <dbReference type="OMA" id="WDSHVRG"/>
    <dbReference type="OrthoDB" id="77607at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033260">
        <property type="term" value="P:nuclear DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040050">
        <property type="entry name" value="ZNF830-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13278">
        <property type="entry name" value="ZINC FINGER PROTEIN 830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13278:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="57"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="347"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="126"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="168"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA55917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="43920" checksum="638F618D7C7C97EE" modified="2011-12-14" version="1">MADVRSLLRQQRTARRIDHPHAAYSDAGKLLCLACHEPVRSESLWDSHVRSAAHKAKAASKSITGGAAPATVDSQTGATSQKRKQQEYHDVDDREAEMLDAADTEEATRRKRSRIDAATAEQDYPTTTTTSNKTAAAAMPSPAGSSTPNTNSGSQNSSSRNGGGRTPQSQTHTPPLTRRQSGTPVLGVEMQMPSRPATPNAPRDGSNAGGAGAGAGGAAVGLGVRQSATTPAAAAPATTAAPVAASGEPAPIDEDEWAAFEREVVNAVPATAAAEDGAVISAAPMTAEEVAAAASEEDGRAKRRAAADIELEDEKEEAKRALEEEFEEMEELEARVRRLKERREALRSRSVRGLNAASAAAVPPSTKLHKEGISEEPVGGEREEPSKASKEGGQDENEDDEDDDDDDDFENFRLRR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2014-07-09" modified="2025-02-05" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWS3</accession>
    <name>XYN3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Endo-1,4-beta-xylanase 3</fullName>
            <shortName>Xylanase 3</shortName>
            <ecNumber>3.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>1,4-beta-D-xylan xylanohydrolase 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">XYL3</name>
        <name type="ORF">MGG_08331</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text>Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715734.1">
        <property type="nucleotide sequence ID" value="XM_003715686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWS3"/>
    <dbReference type="SMR" id="G4MWS3"/>
    <dbReference type="STRING" id="242507.G4MWS3"/>
    <dbReference type="CAZy" id="GH11">
        <property type="family name" value="Glycoside Hydrolase Family 11"/>
    </dbReference>
    <dbReference type="GlyCosmos" id="G4MWS3">
        <property type="glycosylation" value="2 sites, No reported glycans"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_08331T0">
        <property type="protein sequence ID" value="MGG_08331T0"/>
        <property type="gene ID" value="MGG_08331"/>
    </dbReference>
    <dbReference type="GeneID" id="2678467"/>
    <dbReference type="KEGG" id="mgr:MGG_08331"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08331"/>
    <dbReference type="eggNOG" id="ENOG502RXA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWS3"/>
    <dbReference type="OMA" id="ISLYGWT"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="PHI-base" id="PHI:2211"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.180:FF:000001">
        <property type="entry name" value="Endo-1,4-beta-xylanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018208">
        <property type="entry name" value="GH11_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF2">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00776">
        <property type="entry name" value="GH11_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0326">Glycosidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0624">Polysaccharide degradation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000429621" description="Endo-1,4-beta-xylanase 3">
        <location>
            <begin position="20"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="3">
        <location>
            <begin position="45"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="236" mass="25555" checksum="317AF862291B17E2" modified="2011-12-14" version="1" precursor="true">MQILTWALAALAAIPAVTAAPVETVEASSMDELVERSPNVTLVARGTPSSTGTHNGFYYSHWTDNAGADVTYSMGGGGQFSYTWRNSGNFVGGKGWNPGNAGRVINYSGSYSPQGNSYLAVYGWTRNPLIEYYVVESFGSYNPSSGATNRGSFTSDGSTYDILVSTRYNQPSIDGTKTFQQFWSVRRNKRASGTVTFANHVNAWRNAGLNLGNQWNYQILAVEGYHSSGSASMTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWW6</accession>
    <name>G4MWW6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715777.1">
        <property type="nucleotide sequence ID" value="XM_003715729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWW6"/>
    <dbReference type="GeneID" id="12986774"/>
    <dbReference type="KEGG" id="mgr:MGG_15954"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15954"/>
    <dbReference type="HOGENOM" id="CLU_1796849_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWW6"/>
    <dbReference type="OrthoDB" id="10580262at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="144" mass="16111" checksum="75DB2F5C40A0C2FD" modified="2011-12-14" version="1">MDKKKVDASGKVRNATINNCTALHWHRDLQVYQSFPNQVPYHDQHLAPSLPVLPVALPDGVHQQRISHLRGQPKIFASSIEQLLPQRFLIGSNCTQLHPLLTTTTDPHVPSPKNLATPGAIRQNAWKLVKFVSFGFVYSLIFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX96</accession>
    <name>G4MX96_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ent-kaurene oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_12479</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715801.1">
        <property type="nucleotide sequence ID" value="XM_003715753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX96"/>
    <dbReference type="SMR" id="G4MX96"/>
    <dbReference type="GeneID" id="5051073"/>
    <dbReference type="KEGG" id="mgr:MGG_12479"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12479"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_3_1"/>
    <dbReference type="InParanoid" id="G4MX96"/>
    <dbReference type="OMA" id="CIPAMHR"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="519" mass="57870" checksum="096C3507A93EA0CE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXB8</accession>
    <name>G4MXB8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putidaredoxin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_08262</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715823.1">
        <property type="nucleotide sequence ID" value="XM_003715775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXB8"/>
    <dbReference type="SMR" id="G4MXB8"/>
    <dbReference type="STRING" id="242507.G4MXB8"/>
    <dbReference type="GeneID" id="2678596"/>
    <dbReference type="KEGG" id="mgr:MGG_08262"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08262"/>
    <dbReference type="eggNOG" id="KOG1336">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003291_4_2_1"/>
    <dbReference type="InParanoid" id="G4MXB8"/>
    <dbReference type="OMA" id="PRCTHYG"/>
    <dbReference type="OrthoDB" id="6029at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03478">
        <property type="entry name" value="Rieske_AIFL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050446">
        <property type="entry name" value="FAD-oxidoreductase/Apoptosis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028202">
        <property type="entry name" value="Reductase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43557">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43557:SF2">
        <property type="entry name" value="RIESKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14759">
        <property type="entry name" value="Reductase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="10">
        <location>
            <begin position="57"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA56016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="598" mass="63346" checksum="202458EFB47F1CD4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXD5</accession>
    <name>G4MXD5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_15411</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713272.1">
        <property type="nucleotide sequence ID" value="XM_003713224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXD5"/>
    <dbReference type="SMR" id="G4MXD5"/>
    <dbReference type="GeneID" id="12986178"/>
    <dbReference type="KEGG" id="mgr:MGG_15411"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15411"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="InParanoid" id="G4MXD5"/>
    <dbReference type="OMA" id="EIDWIGH"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF12">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA53465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="54665" checksum="D0835092BE467CA6" modified="2011-12-14" version="1">MLLGYDVSNVANIQASVYHAFGHVELLTWVAIGYTALNVCMMPLCRRLSAFGNLKVQFYIYTLIFAAGAAIAGAAPDINCVIIGRAITGIGGAGLYQGIMLYNFKFSSAYEAPRGQAVIGTGFAIGLVLGPIVGGAFAENPHATWRWAMFINIPILAVLCAGWKVFLPPLFISKQTASHAWVDVDWLGWILHCASFLMLFSSLIFSGSHWPWDSYSAIVAWVFAGLLFSMYAVQQHLCIWTTRKYRIFPADALGEVRTVLPVGLSTAMAAAAYGITLYYTLLFFSFTRGFNPVEAAVHLLPYIGTFVGMTVLSSALLPRLRLYPVLYVLGGALMIIGGALQTSMTADSPVGLVMGNLALVGAGVGLVFQQGAAVLKTLARSDATKESDHVVVFLIMQLGGVALFMSVGGCIFQNLGFKYVNDALVDAGVRISDAEVRQALGGLDSAFLGQAEQGLARVVVEQISRAIGNTFFIVVGAGAVVFCLAFVMKWQRLDFKPKPVATELSGPQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXR2</accession>
    <name>G4MXR2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">chitinase</fullName>
            <ecNumber evidence="1">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08054</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.14" evidence="1"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715006.1">
        <property type="nucleotide sequence ID" value="XM_003714958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXR2"/>
    <dbReference type="SMR" id="G4MXR2"/>
    <dbReference type="STRING" id="242507.G4MXR2"/>
    <dbReference type="GeneID" id="2678312"/>
    <dbReference type="KEGG" id="mgr:MGG_08054"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08054"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031465_2_0_1"/>
    <dbReference type="InParanoid" id="G4MXR2"/>
    <dbReference type="OMA" id="VMTYDMM"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="PHI-base" id="PHI:8753"/>
    <dbReference type="PHI-base" id="PHI:8806"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140593">
        <property type="term" value="C:host apoplast"/>
        <property type="evidence" value="ECO:0000315"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140320">
        <property type="term" value="F:PAMP receptor decoy activity"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048315">
        <property type="term" value="P:conidium formation"/>
        <property type="evidence" value="ECO:0000315"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052034">
        <property type="term" value="P:effector-mediated suppression of host pattern-triggered immunity"/>
        <property type="evidence" value="ECO:0000315"/>
        <property type="project" value="PHI-base"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000159">
        <property type="entry name" value="Class V chitinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF378">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465501" description="chitinase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="28"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA55199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="397" mass="43834" checksum="D66CCC1B8441043E" modified="2011-12-14" version="1">MAGLVGIFLLICGVLTSLISITPVNQSPRCVMYLTGQHNVVPDISELRHVTHVALAFMQSPIFNEDSRKEWPLFTSVETVRRQFLPGTKVMIAIGGWGDVAGFETAAASAESRKRFAANVARMVEATGADGIDLDWEYPGGNGEDYKKVPNKQREWEIEAYPLLVAEVRSAIGPDKVLSAAVPGLERDLIAFTRETVPRILRHLDFLNVMTYDLMNRRDNVTKHHTGVQLSLDSIDAYMARGARPSQLNLGFAFYVKYFQTRHAECSGPGKAIGCPTLLLEDPDTGGDLGRTGGFSWHDTVPKDVEASFQKALRNGVYDEIGGGFYYWDEEEDRWWSFDDAGAISRKFDSIFAARNLGGVFAWGLGEDAPHFEHLGAVNSRLDAITKSGAGRPETEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY64</accession>
    <name>G4MY64_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thioredoxin reductase</fullName>
            <ecNumber evidence="8">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_01284</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="8"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714202.1">
        <property type="nucleotide sequence ID" value="XM_003714154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY64"/>
    <dbReference type="SMR" id="G4MY64"/>
    <dbReference type="FunCoup" id="G4MY64">
        <property type="interactions" value="237"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MY64"/>
    <dbReference type="GeneID" id="2679718"/>
    <dbReference type="KEGG" id="mgr:MGG_01284"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01284"/>
    <dbReference type="eggNOG" id="KOG0404">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031864_5_1_1"/>
    <dbReference type="InParanoid" id="G4MY64"/>
    <dbReference type="OMA" id="GPCHVLK"/>
    <dbReference type="OrthoDB" id="371245at2759"/>
    <dbReference type="PHI-base" id="PHI:6674"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000064">
        <property type="entry name" value="Thioredoxin reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050097">
        <property type="entry name" value="Ferredoxin-NADP_redctase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48105">
        <property type="entry name" value="THIOREDOXIN REDUCTASE 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0274">FAD</keyword>
    <keyword evidence="2 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="10">
        <location>
            <begin position="4"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA54395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="328" mass="35234" checksum="3670E74DAF6EFB7D" modified="2011-12-14" version="1">MHSKVVIIGSGPAAHTAAIYLARANLKPVMYEGFMANGTAAGGQLTTTTDVENFPGFPKGIGGQELMDAMREQSSRFETEIISETVAKVDLSSRPFKYCTEWSPEVMHTADTLVIATGASARRLGLPGEDKYWQNGISACAVCDGAVPIFRNKPLFVIGGGDSAAEEAMFLTKYGSHVTVLVRKDKLRASSIMAKRLLSHPKVTVKFNSVGVEVKGGEDGLMSHMVIKDVVTGKEETLEANGLFYAIGHDPATQLVKGQLETDEEGYIVTKPGTPLTSVEGVFACGDVQDKRYRQAITSAGSGCMAAMDAEKFLAEQEDVEPDREARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYM9</accession>
    <name>G4MYM9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxy-cis,cis-muconate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714261.1">
        <property type="nucleotide sequence ID" value="XM_003714213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYM9"/>
    <dbReference type="SMR" id="G4MYM9"/>
    <dbReference type="STRING" id="242507.G4MYM9"/>
    <dbReference type="GeneID" id="2679375"/>
    <dbReference type="KEGG" id="mgr:MGG_01335"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01335"/>
    <dbReference type="eggNOG" id="ENOG502SIAZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045869_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYM9"/>
    <dbReference type="OMA" id="VQNYEYQ"/>
    <dbReference type="OrthoDB" id="1715191at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000244">
        <property type="entry name" value="Carboxy-cis,cis-muconate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF4">
        <property type="entry name" value="CYCLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75011">
        <property type="entry name" value="3-carboxy-cis,cis-mucoante lactonizing enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="372" mass="41690" checksum="515E98356FAAFFA9" modified="2011-12-14" version="1">MPLHHLMIGTWTPPGAIFTVQFDDEKLDIKLVKRTEIPKDEPISWMAFDHARKNIYGSAMKKWSSFAVKSPSEIVHEASHPMGGDPKAASPDTNTRAIFLLPATKPPYAVYCNPFYKPHAGYGNIFNVSDTGALATNVQDYPYQPDSGIHGMVFDPPTETYLYSADLSANRLWVHRRHLPGRNPAEVELVGSIEAPDPGDHPRWVAMHPTGKYLYALMEAGNRICEYVIDPQTHMPVYTHHSYPLVPPGMPKKDRETGKGLYRSDVCAVSSSGRYLFASARSNSFDLTGYIAAFRLRDDGSIEEQLCLNPTPTSGGHSNAVSPCPWSDEWVAMTDDEQGWIEMFRWEGEFLARVARLRIPEPGFGMNAIWYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYP6</accession>
    <name>G4MYP6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-lysine N-methyltransferase EFM6</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Elongation factor methyltransferase 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">EFM6</name>
        <name evidence="3" type="ORF">MGG_01349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714278.1">
        <property type="nucleotide sequence ID" value="XM_003714230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYP6"/>
    <dbReference type="SMR" id="G4MYP6"/>
    <dbReference type="FunCoup" id="G4MYP6">
        <property type="interactions" value="399"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYP6"/>
    <dbReference type="GeneID" id="2679126"/>
    <dbReference type="KEGG" id="mgr:MGG_01349"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01349"/>
    <dbReference type="eggNOG" id="KOG2793">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055721_2_1_1"/>
    <dbReference type="InParanoid" id="G4MYP6"/>
    <dbReference type="OMA" id="ATHMLRD"/>
    <dbReference type="OrthoDB" id="407325at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03198">
        <property type="entry name" value="Methyltr_EFM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033684">
        <property type="entry name" value="EFM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF152">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EFM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="185"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="343" mass="38103" checksum="2481A32B58A1B50E" modified="2011-12-14" version="1">MHYFIGRSISQNLLFAQNGSCHSQSFVLCSRQKGVKPQRTKTPLKASGLIGLTTQLTALIFTTPATARDKLKAKIRRRKFTPRSRGQKQENNKMKDIINDRSSSPPVFSPLAIDADLAPLPEYKAAGETKINFGGLLPATAPLRLHEDLSSGCGGQLWPAGMVLATHMLRDRRSSIGRERILELGAGGGLVSLAVARGCDVETPMLITDQLEMLALMEHNIRLNEVEDKAKALILNWGEPLPQQVVELKPTVVLAADCVYFEPAFPLLLQTLTDLLALSPPKECTVYFCFKKRRRADMQFLKKAQKMFSVVEVPDQDRPVFSRQNLFLYAIISKEEAIKVTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZS8</accession>
    <name>G4MZS8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_13325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711179.1">
        <property type="nucleotide sequence ID" value="XM_003711131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZS8"/>
    <dbReference type="GeneID" id="5050261"/>
    <dbReference type="KEGG" id="mgr:MGG_13325"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13325"/>
    <dbReference type="HOGENOM" id="CLU_1731858_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZS8"/>
    <dbReference type="OrthoDB" id="10619916at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465856" evidence="2">
        <location>
            <begin position="21"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="151" mass="15952" checksum="D613995C61D51A50" modified="2011-12-14" version="1">MKALLLVSVFILCRCHRVSCQIITTVTELPSGPITLPFPIPTGTPTIIFIPTGNITFVFPGGKPTSLPPGASSSTTGGDGDVPDPTPEPNSAAYNPARGEKVEFIGGDIRSIEDAEDDLVNDLFGVDASDDDGNDGEERRSRDTNDGFTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZU0</accession>
    <name>G4MZU0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09087</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711191.1">
        <property type="nucleotide sequence ID" value="XM_003711143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZU0"/>
    <dbReference type="SMR" id="G4MZU0"/>
    <dbReference type="STRING" id="242507.G4MZU0"/>
    <dbReference type="GeneID" id="2680006"/>
    <dbReference type="KEGG" id="mgr:MGG_09087"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09087"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="InParanoid" id="G4MZU0"/>
    <dbReference type="OMA" id="MATHYGI"/>
    <dbReference type="OrthoDB" id="1669814at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF63">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="230" mass="24937" checksum="3A4B7566FAA278B7" modified="2011-12-14" version="1">MATHYGINTTGRVYSITGGASGIGLRKEVKEINQDTEVYLEDVDVGDNAQVQDWVQRIIKTSGALHGSANVAGIPQKAYTGGRPAILIESDQEWERILRVNLDGVKYCTRAQVEAMLSMDKGSHPAIVNVTSRWHSRTMLAPMPTKSAKPHASISPRPLPTTSARSTLTPMTKVFFGDIPEGKFEETMEAYGLPPTPLQPEDVARVIVWLLSENSLDVNGNGLPVGGSEP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2024-10-02" modified="2025-02-05" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0X3</accession>
    <name>CHS5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chitin synthase 5</fullName>
            <ecNumber evidence="8">2.4.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Chitin-UDP acetyl-glucosaminyl transferase 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Class-V chitin synthase 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CHS5</name>
        <name type="ORF">MGG_13014</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2012" name="PLoS Pathog." volume="8" first="e1002526" last="e1002526">
            <title>Different chitin synthase genes are required for various developmental and plant infection processes in the rice blast fungus Magnaporthe oryzae.</title>
            <authorList>
                <person name="Kong L.A."/>
                <person name="Yang J."/>
                <person name="Li G.T."/>
                <person name="Qi L.L."/>
                <person name="Zhang Y.J."/>
                <person name="Wang C.F."/>
                <person name="Zhao W.S."/>
                <person name="Xu J.R."/>
                <person name="Peng Y.L."/>
            </authorList>
            <dbReference type="PubMed" id="22346755"/>
            <dbReference type="DOI" id="10.1371/journal.ppat.1002526"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>INDUCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="5 8">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer (Probable). May play a minor overlapping role with CHS6 in growth and differentiation (PubMed:22346755).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16638"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="5">Expression is induced in vegetative hyphae and infected rice leaves.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="5">Does not affect vegetative growth (PubMed:22346755). Does not significantly changes in the chitin content in vegetative hyphae, nor in conidia (PubMed:22346755).</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chitin synthase family. Class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="8"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712158.1">
        <property type="nucleotide sequence ID" value="XM_003712110.1"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N0X3"/>
    <dbReference type="EnsemblFungi" id="MGG_13014T0">
        <property type="protein sequence ID" value="MGG_13014T0"/>
        <property type="gene ID" value="MGG_13014"/>
    </dbReference>
    <dbReference type="GeneID" id="5048948"/>
    <dbReference type="KEGG" id="mgr:MGG_13014"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13014"/>
    <dbReference type="eggNOG" id="KOG2571">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000192_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0X3"/>
    <dbReference type="OMA" id="RLAEWAN"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000010">
        <property type="entry name" value="Chitin synthase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF13">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000460879" description="Chitin synthase 5">
        <location>
            <begin position="1"/>
            <end position="1787"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="747"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="783"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1445"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1478"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1506"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="3">
        <location>
            <begin position="1729"/>
            <end position="1785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1628"/>
            <end position="1657"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="643"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="657"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="668"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="695"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="894"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="1018"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="1420"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="2">
        <location>
            <position position="1533"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="22346755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="6">
        <source>
            <dbReference type="PubMed" id="22346755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="7"/>
    <evidence type="ECO:0000305" key="8">
        <source>
            <dbReference type="PubMed" id="22346755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA52351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1787" mass="197635" checksum="E6AD1E351121E3FF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0Y0</accession>
    <name>G4N0Y0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF423 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_09572</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712165.1">
        <property type="nucleotide sequence ID" value="XM_003712117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0Y0"/>
    <dbReference type="GeneID" id="2680547"/>
    <dbReference type="KEGG" id="mgr:MGG_09572"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09572"/>
    <dbReference type="eggNOG" id="KOG3472">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096548_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0Y0"/>
    <dbReference type="OMA" id="VEYQFYH"/>
    <dbReference type="OrthoDB" id="269173at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006696">
        <property type="entry name" value="DUF423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04241">
        <property type="entry name" value="DUF423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="15650" checksum="E5758999B985D346" modified="2011-12-14" version="1">MASPNESSPLLPDPNNKPSKRDEMSALTYWRVGAVYGATAVAMGAFGAHGLKKRITDPQKIASWGTAAHYQLLHSGAVMLAASVGTGNPVAAGLFTAGMTMFSGSIYALILDPERFKFLGPVTPIGGVCLIAGWIALGFTKRGAFPRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4N177</accession>
    <name>G4N177_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711363.1">
        <property type="nucleotide sequence ID" value="XM_003711315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N177"/>
    <dbReference type="GeneID" id="12987043"/>
    <dbReference type="KEGG" id="mgr:MGG_16644"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16644"/>
    <dbReference type="HOGENOM" id="CLU_2427445_0_0_1"/>
    <dbReference type="InParanoid" id="G4N177"/>
    <dbReference type="OrthoDB" id="10595029at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="91" mass="10563" checksum="0E731CD2373E9167" modified="2011-12-14" version="1">MCRSSRWGRRAVFLITSRYSLDGPDSQFQINHSHLAEPFMISSVCLSFCDEPLLPQLRSENGNEVILTADWPWRKITMKSMMTMSMCIFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N180</accession>
    <name>G4N180_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dihydrodipicolinate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_07462</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711366.1">
        <property type="nucleotide sequence ID" value="XM_003711318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N180"/>
    <dbReference type="SMR" id="G4N180"/>
    <dbReference type="STRING" id="242507.G4N180"/>
    <dbReference type="GeneID" id="2683382"/>
    <dbReference type="KEGG" id="mgr:MGG_07462"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07462"/>
    <dbReference type="eggNOG" id="ENOG502QWNS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_0_2_1"/>
    <dbReference type="InParanoid" id="G4N180"/>
    <dbReference type="OMA" id="QAIKLSM"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF24">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHETASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G11920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="2">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001365-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="323" mass="34146" checksum="7D7A6A38D5204ADA" modified="2011-12-14" version="1">MSSTNGNAGSRRALPCGIYAPTMTFFDPETEELDIPTIKKHAERLARAGLAGLVTMGSNGEAVHCTREEKVAVTRATREALDAAGFPAVPIIVGATEGSVKGTIELCRACADVGADAVLLLPPSYYRGFMDDEAISSYFHAVADSSPIPIVLYNYPGAVAGVDMDSDLIIKLAEHPNIVGTKFTCGSTGKLTRVATATKAKTPFAEGSGYMAFGGICDFTVQTLASGGSGIIAGGANVMPKVCVKVWNLWAEGKRDEAIELQKVLSKGDWVLTKAAIAGTKQAIQSYYGYGGYPRRPLKRLDAAKVSAIEEGVREIMDIEKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1F1</accession>
    <name>G4N1F1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Impact N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09513</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712229.1">
        <property type="nucleotide sequence ID" value="XM_003712181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1F1"/>
    <dbReference type="SMR" id="G4N1F1"/>
    <dbReference type="STRING" id="242507.G4N1F1"/>
    <dbReference type="GeneID" id="2680521"/>
    <dbReference type="KEGG" id="mgr:MGG_09513"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09513"/>
    <dbReference type="eggNOG" id="KOG3299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031573_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1F1"/>
    <dbReference type="OMA" id="ELDKRAW"/>
    <dbReference type="OrthoDB" id="514070at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF4">
        <property type="entry name" value="IMPACT N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Impact N-terminal" evidence="3">
        <location>
            <begin position="284"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="568" mass="61423" checksum="C98C05A4A6777D3F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1H8</accession>
    <name>G4N1H8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mitochondrial chaperone BCS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_13867</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713052.1">
        <property type="nucleotide sequence ID" value="XM_003713004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1H8"/>
    <dbReference type="SMR" id="G4N1H8"/>
    <dbReference type="STRING" id="242507.G4N1H8"/>
    <dbReference type="GeneID" id="5049363"/>
    <dbReference type="KEGG" id="mgr:MGG_13867"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13867"/>
    <dbReference type="eggNOG" id="KOG0743">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010189_7_0_1"/>
    <dbReference type="InParanoid" id="G4N1H8"/>
    <dbReference type="OMA" id="ANDEKWE"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="32"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="270" mass="30472" checksum="E28C724EB6C0C341" modified="2011-12-14" version="1">MLPEDHELLFVLLKVYLDPKSEEWYANHGIPLRRGYLFHGPPGTGKTSLSLALADFFGLDIYVINLAEPALTDNSLLELANDVPERCIVLLENINTVGLKRFEVKKLKQIRESSGRLAKRNGVTIGGVLNAFDGAASQEGRVLILATNKPASLDEALIRPGRVDLKLCFDNITKNHARDLFWRMYTPDTSAETNELVKLAAEFGCKISEKIFSPAEVPNYLIMHKDQPRQALSGVTDWVEAMKQKSRRYRGKPCAKVPTKCRKKMKRHWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1W2</accession>
    <name>G4N1W2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712284.1">
        <property type="nucleotide sequence ID" value="XM_003712236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1W2"/>
    <dbReference type="SMR" id="G4N1W2"/>
    <dbReference type="STRING" id="242507.G4N1W2"/>
    <dbReference type="ESTHER" id="mago7-a4qua7">
        <property type="family name" value="Bacterial_esterase"/>
    </dbReference>
    <dbReference type="GeneID" id="2680511"/>
    <dbReference type="KEGG" id="mgr:MGG_09468"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09468"/>
    <dbReference type="eggNOG" id="ENOG502REH0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038297_1_0_1"/>
    <dbReference type="InParanoid" id="G4N1W2"/>
    <dbReference type="OMA" id="GNGHMVF"/>
    <dbReference type="OrthoDB" id="9978720at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd12809">
        <property type="entry name" value="Esterase_713_like-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF4">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465639" description="AB hydrolase-1 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="79"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="388" mass="42007" checksum="061A398FFAC58839" modified="2011-12-14" version="1">MQVPKVAVLLAALTLGGSASSVPSQKPGCGSEIPAVRTYFMVGGQYVDDGTGTEEHVFRDQMYVEKLLPVQGVKQKHPLVLIHGQAQTGTNFLNKPDGGRGWASLFVREGYEVYVVDQTLRGRSAWQPGHNADKQSTYSAELISKRFTAVQKYSLWPQAVNHTQWPGSGEMGDPVFDAFYSSNVQFVSNATYQQETVRDAGAKLLDIIGRPAILVGHSQGGILPLVIADAKPDLTAGLIMLEPTGPPFREAVFSDKPARPYGLTDIPLAFDPAVSDPKTDLVQQVFPARADGGVNGSSVDCVMQKESDPAPRKLANLASKDILLVTGEASYHAPYDYCTAKFLVQAGCEKTKHVELGDVGIHGNGHMFFMESNSDDIQKLVSKWIQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2E2</accession>
    <name>G4N2E2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Erythrocyte band 7 integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_07912</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713154.1">
        <property type="nucleotide sequence ID" value="XM_003713106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2E2"/>
    <dbReference type="SMR" id="G4N2E2"/>
    <dbReference type="STRING" id="242507.G4N2E2"/>
    <dbReference type="GeneID" id="2683839"/>
    <dbReference type="KEGG" id="mgr:MGG_07912"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07912"/>
    <dbReference type="eggNOG" id="KOG2620">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024949_1_1_1"/>
    <dbReference type="InParanoid" id="G4N2E2"/>
    <dbReference type="OMA" id="YLQMLPK"/>
    <dbReference type="OrthoDB" id="434619at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="STML2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="94"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="31"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="423" mass="44787" checksum="5E14EC167F1CCB75" modified="2011-12-14" version="1">MATALVNRSNPAALPAVRRTIAAAAGAIGTTSTPTTSLVLSSPRQQQRNRQQQRRTFLEQAGSDASKAGSAGAGPGGRGAIPTYFQRERLPANTVIRFVPQQTAWVVERMGKFHRILEPGLAILVPFLDRIAYVKSLKEVAIEIPSQSAITADNVTLELDGVLYTRVFDAYKASYGVEDAEYAISQLAQTTMRSEIGQLTLDHVLKERAALNTNITAAINEAAQAWGVTCLRYEIRDIHAPTAVVEAMHRQVTAERSKRAEILDSEGQRQSAINIAEGRKQSVILASEALKAEKINRAEGEAEAILLKARATAQGIDQVARSMAEGKQAAQGAVNLSVAEKYVEAFGKLAKEGTAVVVPGNVGDIGGMIATALSVYGKVGAVQGQANGGAVAKVEEATVSAPGTGDAVKDSIVADFDKATKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2J8</accession>
    <name>G4N2J8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MGG_07597</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711514.1">
        <property type="nucleotide sequence ID" value="XM_003711466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2J8"/>
    <dbReference type="STRING" id="242507.G4N2J8"/>
    <dbReference type="GeneID" id="2683517"/>
    <dbReference type="KEGG" id="mgr:MGG_07597"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07597"/>
    <dbReference type="eggNOG" id="KOG4686">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024516_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2J8"/>
    <dbReference type="OMA" id="FMNVFTN"/>
    <dbReference type="OrthoDB" id="424834at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="20" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EHA51707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="408" mass="44060" checksum="49A0120C6D881766" modified="2011-12-14" version="1">MAATHDVESRTGKQPEPLVNEEIPKETSSSSSAMEEVDGARSNPPLSWKITAVVLISCISFGSSWSSGITGALKSTLKKELHINNKQFSLLEASEDFMVTLLILASGMVTDRIGGAGAMLYGNIIYSIGSIIVAAGAEVRSFNLMIGGRVILALGDIATQVAQYKVFSSWFSPNNGFASTLGLELGIKKIGGFVGKSSANIIAQNTGNFAWVFWIAVFMNVFTNILTWVFHRFNSVAHKKFSNVTDPATGEKLTEKSKRFEPKKVLELPWVFWAVIAFSMFQTSTAVVFTQNATELAEKRFKTDSITAGWYSATLQYAGFFLVPCIGAFIDILGNRITLLTICGTGVFLAMDLINWATDTKGTAAAFGIYAVAYVLGPTTIIDSIRTSLWDASTFGSAYAVKIATNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2K3</accession>
    <name>G4N2K3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_13429</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711519.1">
        <property type="nucleotide sequence ID" value="XM_003711471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2K3"/>
    <dbReference type="SMR" id="G4N2K3"/>
    <dbReference type="STRING" id="242507.G4N2K3"/>
    <dbReference type="CAZy" id="GH20">
        <property type="family name" value="Glycoside Hydrolase Family 20"/>
    </dbReference>
    <dbReference type="GeneID" id="2683521"/>
    <dbReference type="KEGG" id="mgr:MGG_13429"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13429"/>
    <dbReference type="eggNOG" id="KOG2499">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010969_1_0_1"/>
    <dbReference type="InParanoid" id="G4N2K3"/>
    <dbReference type="OMA" id="GWQWTPA"/>
    <dbReference type="OrthoDB" id="428480at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06564">
        <property type="entry name" value="GH20_DspB_LnbB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052764">
        <property type="entry name" value="GH20_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43678:SF1">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43678">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465896" description="beta-N-acetylhexosaminidase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase bacterial type N-terminal" evidence="10">
        <location>
            <begin position="118"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="9">
        <location>
            <begin position="181"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="731"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="735"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR625705-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA51712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="771" mass="85335" checksum="12ECD1B006CEFE8C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2S5</accession>
    <name>G4N2S5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">alkaline phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_04900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712387.1">
        <property type="nucleotide sequence ID" value="XM_003712339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2S5"/>
    <dbReference type="SMR" id="G4N2S5"/>
    <dbReference type="STRING" id="242507.G4N2S5"/>
    <dbReference type="GeneID" id="2675455"/>
    <dbReference type="KEGG" id="mgr:MGG_04900"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04900"/>
    <dbReference type="eggNOG" id="KOG4126">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008539_3_0_1"/>
    <dbReference type="InParanoid" id="G4N2S5"/>
    <dbReference type="OMA" id="GSADTEY"/>
    <dbReference type="OrthoDB" id="5818554at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF72">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465911" description="alkaline phosphatase" evidence="5">
        <location>
            <begin position="23"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="2">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA52580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="668" mass="73143" checksum="08E3A89DB3590560" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2T9</accession>
    <name>G4N2T9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713195.1">
        <property type="nucleotide sequence ID" value="XM_003713147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2T9"/>
    <dbReference type="GeneID" id="2683879"/>
    <dbReference type="KEGG" id="mgr:MGG_07952"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07952"/>
    <dbReference type="HOGENOM" id="CLU_2320862_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2T9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465707" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="10164" checksum="80867BBBF8065A6D" modified="2011-12-14" version="1">MKSLFIYLLIWGNRSSVSAAGPGEAAEAGATGEGILSGEELAQQELPEGFGRGGFGWSGSGRAACRSVDHLRDAAAGDETFDNQDNDSQGELPTNGGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N347</accession>
    <name>G4N347_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712410.1">
        <property type="nucleotide sequence ID" value="XM_003712362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N347"/>
    <dbReference type="GeneID" id="2675648"/>
    <dbReference type="KEGG" id="mgr:MGG_04919"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04919"/>
    <dbReference type="eggNOG" id="ENOG502S2ZP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051199_2_0_1"/>
    <dbReference type="InParanoid" id="G4N347"/>
    <dbReference type="OMA" id="HVECMNR"/>
    <dbReference type="OrthoDB" id="18530at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40368:SF1">
        <property type="entry name" value="YALI0F14399P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465718" evidence="2">
        <location>
            <begin position="30"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="306" mass="33292" checksum="5676C2C7C724604F" modified="2011-12-14" version="1">MQPMAPPTSSMVVLLLSLTLLAFAGAAQATADSLPSYHFGAPISVECLNRSSETGEHIELANHELQWIPFPTCNETGKSLEFNYGIETELNCTIPMITDPFFHLLEFYIHSDAPLACRLPSRPWPHVEAVGEKPFKMEYIPLVFALAGTLQLSHLHISTHLNVLLHSTPKHHIHPHDSGVLDSGAAYSTSPLSHITGPAAQTRRLVIGDPLPLSFSVRWFPTPALPKTEGHVEWQGMGGHVYASTVFYAISAFLAGMTCSCVYFWGYVLPKRLRGRALGGATPLGHGLNNGVGNGWGMAPIKRAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3S2</accession>
    <name>G4N3S2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_12956</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712502.1">
        <property type="nucleotide sequence ID" value="XM_003712454.1"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N3S2"/>
    <dbReference type="GeneID" id="5048891"/>
    <dbReference type="KEGG" id="mgr:MGG_12956"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12956"/>
    <dbReference type="eggNOG" id="ENOG502REBM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002541_1_0_1"/>
    <dbReference type="InParanoid" id="G4N3S2"/>
    <dbReference type="OMA" id="MFAREQK"/>
    <dbReference type="OrthoDB" id="2123378at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13278">
        <property type="entry name" value="PH_Bud4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000311">
        <property type="entry name" value="GTP binding protein (Bud4)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012966">
        <property type="entry name" value="AHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052007">
        <property type="entry name" value="Bud4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08174">
        <property type="entry name" value="Anillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="5">
        <location>
            <begin position="1226"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="900"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1057"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1081"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
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            <begin position="285"/>
            <end position="294"/>
        </location>
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            <end position="309"/>
        </location>
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            <end position="375"/>
        </location>
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            <begin position="450"/>
            <end position="464"/>
        </location>
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            <begin position="528"/>
            <end position="549"/>
        </location>
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            <end position="559"/>
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        </location>
    </feature>
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            <begin position="1057"/>
            <end position="1072"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1395" mass="155541" checksum="8AF6535AEC2D05DD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N432</accession>
    <name>G4N432_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">Utp8 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_05048</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003712511.1"/>
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    <dbReference type="SMR" id="G4N432"/>
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    <dbReference type="Proteomes" id="UP000009058">
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    <dbReference type="Pfam" id="PF10395">
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    </feature>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF10395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="949" mass="102475" checksum="C64EE7FC0712BE5F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4N475</accession>
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        <recommendedName>
            <fullName evidence="14">DUF221 family protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="12" type="ORF">MGG_05082</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
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        <property type="protein sequence ID" value="EHA52795.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003712554.1"/>
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    <dbReference type="AlphaFoldDB" id="G4N475"/>
    <dbReference type="SMR" id="G4N475"/>
    <dbReference type="GeneID" id="2675623"/>
    <dbReference type="KEGG" id="mgr:MGG_05082"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05082"/>
    <dbReference type="eggNOG" id="KOG1134">
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    <dbReference type="HOGENOM" id="CLU_009187_1_0_1"/>
    <dbReference type="InParanoid" id="G4N475"/>
    <dbReference type="OMA" id="VVCAWAF"/>
    <dbReference type="OrthoDB" id="2150324at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
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    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Csc1-like"/>
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    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF149">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="603"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="627"/>
            <end position="645"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="657"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="39"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="212"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="393"/>
            <end position="676"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="785"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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            <end position="938"/>
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    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="792"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
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        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="971"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA52795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1027" mass="114271" checksum="9648420DB15D4026" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N535</accession>
    <name>G4N535_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DOA4-independent degradation protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712753.1">
        <property type="nucleotide sequence ID" value="XM_003712705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N535"/>
    <dbReference type="SMR" id="G4N535"/>
    <dbReference type="FunCoup" id="G4N535">
        <property type="interactions" value="734"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N535"/>
    <dbReference type="GeneID" id="2675670"/>
    <dbReference type="KEGG" id="mgr:MGG_05208"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05208"/>
    <dbReference type="eggNOG" id="KOG3230">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069208_1_0_1"/>
    <dbReference type="InParanoid" id="G4N535"/>
    <dbReference type="OMA" id="KMAKMNQ"/>
    <dbReference type="OrthoDB" id="10252926at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="220" mass="25166" checksum="82D6FA2724AC3097" modified="2011-12-14" version="1">MNIIEWAFGKRMTPAERLRKNQRLLDKAIRELDQQRVKLEKQEKTLVTQIKQSAQKNQMGACKIQAKDLVRTRRYIEKFYGMRSQLQQISLRLQTHRTNEQMMQAMKGATMALGSMNRTMNLPSLQRIAAEFERENDIMEQRQELMDDAVDDAMDVGVEEEGDELVEQVLEEIGVDLKNSLGETPQGLQSETVAETRIAQAVGGGSDDDLQARLDSLRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5F7</accession>
    <name>G4N5F7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_09064</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711164.1">
        <property type="nucleotide sequence ID" value="XM_003711116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5F7"/>
    <dbReference type="SMR" id="G4N5F7"/>
    <dbReference type="GeneID" id="2680044"/>
    <dbReference type="KEGG" id="mgr:MGG_09064"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09064"/>
    <dbReference type="eggNOG" id="KOG0671">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_81_11_1"/>
    <dbReference type="InParanoid" id="G4N5F7"/>
    <dbReference type="OMA" id="FRAMDEN"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA51357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="178" mass="20605" checksum="2EC557D74A63DFC0" modified="2011-12-14" version="1">MALQRHGRARKIAKDSRVIAQICVNDNPQHDLPLVPENHRPLELVILDMLWSYPVDMWCLGITVWRMLDTKSFFSHYAGAGEDLDEARHSSLMVGLLGPPPREFLQNSKGSLKYWDENGKWNGLVASPPPSFTLESIWPLKCESRTLSLDFIRKVLCWDPEIRLYPGEAWHHPWVHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5F9</accession>
    <name>G4N5F9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711166.1">
        <property type="nucleotide sequence ID" value="XM_003711118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5F9"/>
    <dbReference type="GeneID" id="12986968"/>
    <dbReference type="KEGG" id="mgr:MGG_16583"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16583"/>
    <dbReference type="HOGENOM" id="CLU_2705292_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5F9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="73" mass="8210" checksum="4DF9A939650F7E8C" modified="2011-12-14" version="1">MFDKKKAFTVSRIVTLGLWELFVTVGSGVPGCAFVIYGFDKYVTIVSIAQYGDSIPRELLLRNLMSWGLVEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5U0</accession>
    <name>G4N5U0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716035.1">
        <property type="nucleotide sequence ID" value="XM_003715987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5U0"/>
    <dbReference type="GeneID" id="12986487"/>
    <dbReference type="KEGG" id="mgr:MGG_15361"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15361"/>
    <dbReference type="HOGENOM" id="CLU_1938579_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5U0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="130" mass="15251" checksum="A3CB1D54187CE4D7" modified="2011-12-14" version="1">MTQLSTRRRVYAETHMFIHDNERYFDDYMVHETHKPPRRLPGPGTAELRKLWLLRPKPTMIHNSGYHYMSLRDNAAKRLTWRGSFEHWNSEGIELHLDRASVDKAGRSAASRTTLSEKRSPRACQFTARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5Z4</accession>
    <name>G4N5Z4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716889.1">
        <property type="nucleotide sequence ID" value="XM_003716841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5Z4"/>
    <dbReference type="GeneID" id="12985475"/>
    <dbReference type="KEGG" id="mgr:MGG_17146"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17146"/>
    <dbReference type="InParanoid" id="G4N5Z4"/>
    <dbReference type="OrthoDB" id="10355682at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466066" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="8020" checksum="75CD54D44D66B5B2" modified="2011-12-14" version="1" fragment="single">MTRLPARFFLSLSLSLCYFFFLRTNIPRPTVEWWPHAHRLKYTRLMVGEAKAGKMCTQILRQAVMAGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N641</accession>
    <name>G4N641_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PITH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PITHD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716084.1">
        <property type="nucleotide sequence ID" value="XM_003716036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N641"/>
    <dbReference type="SMR" id="G4N641"/>
    <dbReference type="STRING" id="242507.G4N641"/>
    <dbReference type="GeneID" id="2678742"/>
    <dbReference type="KEGG" id="mgr:MGG_08563"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08563"/>
    <dbReference type="eggNOG" id="KOG1730">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072377_2_0_1"/>
    <dbReference type="InParanoid" id="G4N641"/>
    <dbReference type="OMA" id="RLVFKPW"/>
    <dbReference type="OrthoDB" id="2635at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045099">
        <property type="entry name" value="PITH1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175">
        <property type="entry name" value="AD039 HT014 THIOREDOXIN FAMILY TRP26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175:SF1">
        <property type="entry name" value="PITH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PITH" evidence="3">
        <location>
            <begin position="25"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="228" mass="24847" checksum="616D62A34BA28C8B" modified="2011-12-14" version="1">MSHCHDEHGGDDHHHHHGEDGHDHSDDLTPALQNSLYTRIEFDKIVTLNEDAHNSGLAVVKKTWAERLTPTPELASDADEQLLMHVPFTGQVKLHSILVRTSDSDSAPRTLRVFANRPESFDFSAAESETPLQEIELSRTSAVQELNVKRAKFGGVARLSLFFVDNFGDGDEDVTRLSYLGFKGEWMPLGRAPANILYEAAANPSDHALKGTSVNAMGSGIGGRGPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6B5</accession>
    <name>G4N6B5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716956.1">
        <property type="nucleotide sequence ID" value="XM_003716908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6B5"/>
    <dbReference type="GeneID" id="2684734"/>
    <dbReference type="KEGG" id="mgr:MGG_06579"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06579"/>
    <dbReference type="HOGENOM" id="CLU_858088_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6B5"/>
    <dbReference type="OMA" id="HDADNET"/>
    <dbReference type="OrthoDB" id="5212965at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="324" mass="36262" checksum="70E68C390B500FC4" modified="2011-12-14" version="1">MSNTSDPQSSPQPSGPTRPRSRPGLLQAYLSMLPIIHDCLERKYTHDADNETLTLRYVAEELLSGNDAKAYGVLRAQECPFHLPEDGFPGRLDATLLSEHGLPKDVARIVDSRNRNEMGELRAFETAIMYNGYAIRPTMTPEARLLLDMRVASHALVVALLKARLLLELRCIRELSSALHHRGVPPEVAEMIVLQMRHWDGDEVKSLVFSHGGRPCGATADGRQKLRDVIANVDGYIQEQEQGIRDLTTLPAAEPIAQSYFLITNVGGMGNIISVGRWFSVLKEDIIWRDCCPAVHMAWHTNTAARKLVWELIGEEEPPLDTQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6J2</accession>
    <name>G4N6J2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ras GTPase-activating-like protein rng2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716181.1">
        <property type="nucleotide sequence ID" value="XM_003716133.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N6J2"/>
    <dbReference type="FunCoup" id="G4N6J2">
        <property type="interactions" value="351"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N6J2"/>
    <dbReference type="GeneID" id="2676766"/>
    <dbReference type="KEGG" id="mgr:MGG_03700"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03700"/>
    <dbReference type="eggNOG" id="KOG2128">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000972_1_1_1"/>
    <dbReference type="InParanoid" id="G4N6J2"/>
    <dbReference type="OMA" id="KGVLVHW"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21206">
        <property type="entry name" value="CH_IQGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05127">
        <property type="entry name" value="RasGAP_IQGAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF14">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="3">
        <location>
            <begin position="287"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="2">
        <location>
            <begin position="1036"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1672" mass="190790" checksum="7619A0B1D12801B5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6M2</accession>
    <name>G4N6M2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Retinol dehydrogenase 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06534</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717010.1">
        <property type="nucleotide sequence ID" value="XM_003716962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6M2"/>
    <dbReference type="SMR" id="G4N6M2"/>
    <dbReference type="FunCoup" id="G4N6M2">
        <property type="interactions" value="243"/>
    </dbReference>
    <dbReference type="GeneID" id="2684689"/>
    <dbReference type="KEGG" id="mgr:MGG_06534"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06534"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_6_1"/>
    <dbReference type="InParanoid" id="G4N6M2"/>
    <dbReference type="OMA" id="NTTWCAT"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="315" mass="34610" checksum="0152B7948B6F913D" modified="2011-12-14" version="1">MFGFFETKFNPTKDIPDLSGKVILVTGGNIGLGQSSVLELARHNPKHIFLAARNEEKARKAIESVSWELGTDKASVVSFLPLDLSSFDSIRKAAETVNSKTDELHILLNNAGIMMTPATTTKEGYEEQFGTNHMGHALLTRLLLPVLEKTAQGGKVDVRIVNLSSAGEGLAPTNAFDDLSRYKSPMEDVASHTRYGVSKLANIYHAQMLARKYPSIKAVSVHPGVVNTNLTRGLKETYPWIVPYVAPIAGALFFKTPAEGAKNQLWASTNEKVISGEFYWPVGLLGKGSEKSKDTEAAEKLWDWTEKELDAYLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6Q7</accession>
    <name>G4N6Q7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Endosomal/vacuolar adapter protein YPT35</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">PX domain-containing protein YPT35</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_15287</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YPT35 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716193.1">
        <property type="nucleotide sequence ID" value="XM_003716145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6Q7"/>
    <dbReference type="SMR" id="G4N6Q7"/>
    <dbReference type="STRING" id="242507.G4N6Q7"/>
    <dbReference type="GeneID" id="12984358"/>
    <dbReference type="KEGG" id="mgr:MGG_15287"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15287"/>
    <dbReference type="eggNOG" id="ENOG502S5IQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070610_1_0_1"/>
    <dbReference type="InParanoid" id="G4N6Q7"/>
    <dbReference type="OMA" id="PINAIMM"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07280">
        <property type="entry name" value="PX_YPT35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037917">
        <property type="entry name" value="Ypt35_PX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="PX" evidence="11">
        <location>
            <begin position="130"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00033728"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00033774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA49874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="240" mass="26314" checksum="FB9CFCBD837B7933" modified="2011-12-14" version="1">MATEVTASAPGDITTTTAPHQSSSSQSPLFADDNRGADLQNDTAHTASRISPVQSPVTAPPYWSPSQSDPPRFFGEHGVSGRAPPPHNGSTESVAPINAIMMHDNETAGEDATPERVSGRDRNRACWAKSVSVTDYVIVNSSTTNIGAFVVWNIRVETLSGSYMNIRKRYSEFDDLRHKLMVTFPNFEAAVPVLPPKSVIAKFRPKFLEKRRSGLQYFLNCILLNPEFSGSPVLKDFLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8B6</accession>
    <name>G4N8B6_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716482.1">
        <property type="nucleotide sequence ID" value="XM_003716434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8B6"/>
    <dbReference type="SMR" id="G4N8B6"/>
    <dbReference type="STRING" id="242507.G4N8B6"/>
    <dbReference type="GeneID" id="5051701"/>
    <dbReference type="KEGG" id="mgr:MGG_13552"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13552"/>
    <dbReference type="eggNOG" id="ENOG502S495">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015886_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="118"/>
            <end position="143"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="429"/>
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        </location>
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            <begin position="121"/>
            <end position="132"/>
        </location>
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            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="453"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="538" mass="58296" checksum="DF13E7B161F181C0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8R9</accession>
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    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
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    <gene>
        <name evidence="2" type="ORF">MGG_17211</name>
        <name evidence="3" type="ORF">MGG_17219</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717373.1">
        <property type="nucleotide sequence ID" value="XM_003717325.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717384.1">
        <property type="nucleotide sequence ID" value="XM_003717336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8R9"/>
    <dbReference type="GeneID" id="12986507"/>
    <dbReference type="GeneID" id="12986515"/>
    <dbReference type="KEGG" id="mgr:MGG_17211"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_17211"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17219"/>
    <dbReference type="OrthoDB" id="3582307at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="150" mass="17378" checksum="8568F1ADDD9C397C" modified="2011-12-14" version="1" fragment="single">RRSTALHCWHTFLSLPRQAPVSWHRARLREELVERRAAVTSISQLSETADVVFTISRARFYGHHFQSYMLIAVPAGGLLYMVAKFSLRWAFYRIVAYACGARGRKLKDVREVFNPRKTGKVDEVAGRHGLDPRICRIWAKRVKAFWPLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8S9</accession>
    <name>G4N8S9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_10115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA51075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="2681726"/>
    <dbReference type="KEGG" id="mgr:MGG_10115"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10115"/>
    <dbReference type="eggNOG" id="ENOG502S9NZ">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OMA" id="PFNDPVN"/>
    <dbReference type="OrthoDB" id="5340910at2759"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
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    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
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        <location>
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            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
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            <begin position="1"/>
            <end position="22"/>
        </location>
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            <begin position="50"/>
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            <end position="506"/>
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        <source>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA51075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="562" mass="59827" checksum="0AD7907EBACC812F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8W8</accession>
    <name>G4N8W8_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12715</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003716533.1"/>
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    <dbReference type="GeneID" id="5050087"/>
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    <dbReference type="InParanoid" id="G4N8W8"/>
    <dbReference type="OrthoDB" id="10502383at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466712" description="Cell wall protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="22343" checksum="85931488565C01D6" modified="2011-12-14" version="1">MRFSILTAVASISGVLAAPPLYGSSRADKIVFAPTAPRVAIGAAAVNAAAAAAPVARAAPAAPRVQQAKEMVTALKADVEGDLADWKSGDVAKMKSKIGTVTSKVDSVSSMVSSILGDVELGGLSEADKKFALGMFADAQELASEVENSMGSIDSNNRAALKPELDILRLDLGGLLGPLLNLLMGLLNGLLGAPKEDPAGKPGGESDGLLGSLLGGLLGGLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N980</accession>
    <name>G4N980_PYRO7</name>
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        <submittedName>
            <fullName evidence="12">Serin endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_03316</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the peptidase S8 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA50325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716644.1">
        <property type="nucleotide sequence ID" value="XM_003716596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N980"/>
    <dbReference type="GeneID" id="2676670"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03316"/>
    <dbReference type="eggNOG" id="KOG4266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4N980"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02124">
        <property type="entry name" value="PA_PoS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1710">
        <property type="entry name" value="Subtilisin-like superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
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        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466298" evidence="9">
        <location>
            <begin position="21"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="159"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="11">
        <location>
            <begin position="628"/>
            <end position="746"/>
        </location>
    </feature>
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        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA50325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="907" mass="96226" checksum="1F363AEF080FFD9F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9V4</accession>
    <name>G4N9V4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716725.1">
        <property type="nucleotide sequence ID" value="XM_003716677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9V4"/>
    <dbReference type="SMR" id="G4N9V4"/>
    <dbReference type="STRING" id="242507.G4N9V4"/>
    <dbReference type="GeneID" id="2676405"/>
    <dbReference type="KEGG" id="mgr:MGG_03249"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03249"/>
    <dbReference type="eggNOG" id="ENOG502S9ZX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_744097_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9V4"/>
    <dbReference type="OMA" id="SMANILD"/>
    <dbReference type="OrthoDB" id="20018at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06320">
        <property type="entry name" value="GCN5L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="372" mass="39925" checksum="9FD4F5E8977480A8" modified="2011-12-14" version="1">MASTEGMSVNTTSTAGSPESHQTRTETMDTTVQSSAASTATTQDMTGSSTSRYQPPSASAASSVFSAPTWWPQLGFRGARGGDTATTLASATGASSRAHVQGSVPPPVTAGPSRRPVDVGLPTSPPSPEQQHQQQANNVAEARAALEASMANILDRELVPRATALHRGERVIKKQQADVVRATGALRQANRQLEEVVEDVSWKLREVGDLQNWTELLEQRFLAVEETMRLVREGDSDEGSCSSCQCSECCSDCGESEWDGSADEGEEVPDANSHNQDRADALNVAVGLEGLPSMSRPVEQRRDNEDPLVSKTSFVDACYVSLPEEAWSPVDIDIACQVPLPEDFLLGEQDDCSDAWVHPQSTIPVEECPRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA19</accession>
    <name>G4NA19_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717584.1">
        <property type="nucleotide sequence ID" value="XM_003717536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA19"/>
    <dbReference type="GeneID" id="2680712"/>
    <dbReference type="KEGG" id="mgr:MGG_09765"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09765"/>
    <dbReference type="eggNOG" id="ENOG502S5M9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073624_0_1_1"/>
    <dbReference type="InParanoid" id="G4NA19"/>
    <dbReference type="OMA" id="QGIDFCK"/>
    <dbReference type="OrthoDB" id="2142503at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36854:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466348" description="Integral membrane protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="22191" checksum="EDE53B716449854E" modified="2011-12-14" version="1">MARITILALLLVAFVTLVASSPPTFCKCTCFKNSTIIPLGTGHAPANPPPAPQPTATTTATATAPTDSPDGQKKPAVLLPRAASSSCTQCNRAFCLQYNLPICKGATEKDVVTQCFARDSRKDQLIVWAFILGTGGLLGWAGLKRALEHQQQRREAAGGMGAGVPVGSVGRSGGMGASRRGGGGAGGGQGDRGDYVYVDGDTDQGEGMSSGIRAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAJ0</accession>
    <name>G4NAJ0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleoside-diphosphate-sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717647.1">
        <property type="nucleotide sequence ID" value="XM_003717599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAJ0"/>
    <dbReference type="SMR" id="G4NAJ0"/>
    <dbReference type="STRING" id="242507.G4NAJ0"/>
    <dbReference type="GeneID" id="2680704"/>
    <dbReference type="KEGG" id="mgr:MGG_09705"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09705"/>
    <dbReference type="eggNOG" id="ENOG502S0JD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_8_4_1"/>
    <dbReference type="InParanoid" id="G4NAJ0"/>
    <dbReference type="OMA" id="MMASLWA"/>
    <dbReference type="OrthoDB" id="9997102at2759"/>
    <dbReference type="PHI-base" id="PHI:2175"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF7">
        <property type="entry name" value="NMRA LIKE REDOX SENSOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="7"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="321" mass="34413" checksum="35017CD03098EE92" modified="2011-12-14" version="1">MASKTPATILVVGATGQQGGAVIRALLEDRRPSTPAPRVLALTRNRQSAKAQQLAGRHAAVELVQGDMSKPEEVFSAAGASDISAVFVVTTPNHGRGPGEDEVAIPFIDAAVAHGVGRVVFSSVDRGGDDRSWTNETDVPHFRQKHLVELHLRDKQQQQQQTPGFSYTIVRPVAFMDNLNPGMACSVMVAAWAAALSPGRKLQLVSVRDVGRVAARALLADLDDGDQGGRYRNAAIGVAGDELSLDQVKEVFSRVTGKTLPQAWWPLGGVLLWALGELGSMFGFFEREGYGVELDETASDEAGRMLGFEAWLKEESGWANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAN9</accession>
    <name>G4NAN9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450 52A13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_08494</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716001.1">
        <property type="nucleotide sequence ID" value="XM_003715953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAN9"/>
    <dbReference type="SMR" id="G4NAN9"/>
    <dbReference type="STRING" id="242507.G4NAN9"/>
    <dbReference type="GeneID" id="2678769"/>
    <dbReference type="KEGG" id="mgr:MGG_08494"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08494"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_27_0_1"/>
    <dbReference type="InParanoid" id="G4NAN9"/>
    <dbReference type="OMA" id="SHDICRA"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="CDD" id="cd11063">
        <property type="entry name" value="CYP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000102">
        <property type="entry name" value="Cytochrome P450 52A5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002974">
        <property type="entry name" value="Cyt_P450_E_CYP52_ascomycetes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF17">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01239">
        <property type="entry name" value="EP450IICYP52"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602402-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA49682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="519" mass="58494" checksum="94A955563C753CA0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBJ3</accession>
    <name>G4NBJ3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717682.1">
        <property type="nucleotide sequence ID" value="XM_003717634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBJ3"/>
    <dbReference type="GeneID" id="12986616"/>
    <dbReference type="KEGG" id="mgr:MGG_17290"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17290"/>
    <dbReference type="HOGENOM" id="CLU_2979581_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBJ3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="58" mass="6233" checksum="477E1980F5674E32" modified="2011-12-14" version="1">MAKIRMLLGWPLENLEVPVDDDDVGVVDRRALCLEQSCSCGAAPAPASHPHRSTSDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC41</accession>
    <name>G4NC41_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_00440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718628.1">
        <property type="nucleotide sequence ID" value="XM_003718580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC41"/>
    <dbReference type="SMR" id="G4NC41"/>
    <dbReference type="STRING" id="242507.G4NC41"/>
    <dbReference type="ESTHER" id="mago7-g4nc41">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
    </dbReference>
    <dbReference type="GeneID" id="2674656"/>
    <dbReference type="KEGG" id="mgr:MGG_00440"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00440"/>
    <dbReference type="eggNOG" id="KOG1516">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_10_5_1"/>
    <dbReference type="InParanoid" id="G4NC41"/>
    <dbReference type="OMA" id="YGTWAFL"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005132200" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="21"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="45"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA49044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="607" mass="65504" checksum="FB2C53E938F9917F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCC0</accession>
    <name>G4NCC0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_00420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718653.1">
        <property type="nucleotide sequence ID" value="XM_003718605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCC0"/>
    <dbReference type="SMR" id="G4NCC0"/>
    <dbReference type="STRING" id="242507.G4NCC0"/>
    <dbReference type="GeneID" id="2674939"/>
    <dbReference type="KEGG" id="mgr:MGG_00420"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00420"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_2_1"/>
    <dbReference type="InParanoid" id="G4NCC0"/>
    <dbReference type="OMA" id="YGWTCDS"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF22">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="78"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA49069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="534" mass="58279" checksum="6ECE593D2ACF0225" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCZ5</accession>
    <name>G4NCZ5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Endoglucanase EG-II</fullName>
            <ecNumber evidence="3">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_00319</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Endoglucanase (EG) that cleaves the internal beta-1,4-glucosidic bonds in cellulose. The degradation of cellulose involves an interplay between different cellulolytic enzymes. Hydrolysis starts with EGs, which cut internal glycosidic linkages to reduce the polymerization degree of the substrate and creates new chain ends for exocellobiohydrolases (CBHs). The CBH release the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain. Finally, beta-1,4-glucosidases hydrolyze the cellobiose and other short cello-oligosaccharides into glucose units.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="3"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718769.1">
        <property type="nucleotide sequence ID" value="XM_003718721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCZ5"/>
    <dbReference type="SMR" id="G4NCZ5"/>
    <dbReference type="STRING" id="242507.G4NCZ5"/>
    <dbReference type="CAZy" id="GH5">
        <property type="family name" value="Glycoside Hydrolase Family 5"/>
    </dbReference>
    <dbReference type="GeneID" id="2674685"/>
    <dbReference type="KEGG" id="mgr:MGG_00319"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00319"/>
    <dbReference type="eggNOG" id="ENOG502QXN4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029718_1_2_1"/>
    <dbReference type="InParanoid" id="G4NCZ5"/>
    <dbReference type="OMA" id="YTDNKLM"/>
    <dbReference type="OrthoDB" id="5823761at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000124">
        <property type="entry name" value="Exported cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142:SF5">
        <property type="entry name" value="CBM1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34142">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="9 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-0873">Pyrrolidone carboxylic acid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466081" description="Endoglucanase EG-II" evidence="15">
        <location>
            <begin position="18"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="16">
        <location>
            <begin position="60"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="344"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="350"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="389"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="430"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00059691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA49185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="522" mass="54856" checksum="BB9D4D4E41F4054A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND02</accession>
    <name>G4ND02_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aspergillopepsin-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_00311</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718776.1">
        <property type="nucleotide sequence ID" value="XM_003718728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND02"/>
    <dbReference type="SMR" id="G4ND02"/>
    <dbReference type="STRING" id="242507.G4ND02"/>
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    <dbReference type="KEGG" id="mgr:MGG_00311"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00311"/>
    <dbReference type="eggNOG" id="ENOG502RJF6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066466_0_1_1"/>
    <dbReference type="InParanoid" id="G4ND02"/>
    <dbReference type="OMA" id="SLNWAGY"/>
    <dbReference type="OrthoDB" id="2862635at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070007">
        <property type="term" value="F:glutamic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13426">
        <property type="entry name" value="Peptidase_G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="entry name" value="Peptidase G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536:SF1">
        <property type="entry name" value="ASPERGILLOPEPSIN, PUTAITVE (AFU_ORTHOLOGUE AFUA_7G01200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00977">
        <property type="entry name" value="SCYTLDPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466460" description="Aspergillopepsin-2" evidence="3">
        <location>
            <begin position="20"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600250-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="32437" checksum="01488C623D7D6DB9" modified="2011-12-14" version="1">MRTFSLLVSLLLLVVSTSAIEIKVVSVTAEDGAKPIDPASIKLVPRPLSPSSIERVRNKTVEDGDPAHAGRRSATPANAVSYSGNWCGAMQNAPASNLVSSVSGWLTAPILDIRHTENRTPQFAASWMGIDGGENCRTALLQGGTTTEIDANGFQTSKAWFEWIPDAAYDIPNMPVAPGDNIHIEVEAITSRKGRITMTNADQPFSIVIELTDGQPLCRRHAEWIVENFRINSNRVPFAKFDDIWFQECEVKLQNGQTWGVDGSRMYYMETVYDVPVCRALEYDNGIFLAESDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDA5</accession>
    <name>G4NDA5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C6 transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718828.1">
        <property type="nucleotide sequence ID" value="XM_003718780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDA5"/>
    <dbReference type="STRING" id="242507.G4NDA5"/>
    <dbReference type="GeneID" id="2674494"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00271"/>
    <dbReference type="eggNOG" id="ENOG502S97T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4NDA5"/>
    <dbReference type="OrthoDB" id="60858at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919:SF2">
        <property type="entry name" value="EXPERA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37919">
        <property type="entry name" value="PROTEIN CBG05606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="31845" checksum="4DB365034CFB9730" modified="2011-12-14" version="1">MLPIHPESPEHTTNSVSFPVPSINTMVQTRSASSTAVPRLSPPPPSPTKRRVSNRSASNTPAPTSAPAAATEVEVTKPLAALRGGSSSSTTSSSSPAILSHTPSTLALAWLAISLPLVAWDTGYIMLRPHSMPGGSWHAPIWVPYALYGQVDYVYGRERWEAGDGFCGAQGTMNIVESLMYLAYLWIWYSNKTATGASGSGAASTRGAVTGRSAGLAMLIMFSACVMTVSKTVLYWLNESWSGFHGIGHNSARDLVALWIIPNGAWIIFPTYLIYAYGREILDSMAPSTHRATEKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDL4</accession>
    <name>G4NDL4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="13">FBP aldolase</shortName>
            <ecNumber evidence="5 13">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_00223</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 13"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718883.1">
        <property type="nucleotide sequence ID" value="XM_003718835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDL4"/>
    <dbReference type="SMR" id="G4NDL4"/>
    <dbReference type="FunCoup" id="G4NDL4">
        <property type="interactions" value="676"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NDL4"/>
    <dbReference type="GeneID" id="2674368"/>
    <dbReference type="KEGG" id="mgr:MGG_00223"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00223"/>
    <dbReference type="eggNOG" id="KOG4153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036923_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDL4"/>
    <dbReference type="OMA" id="PRTWGKL"/>
    <dbReference type="OrthoDB" id="35652at2759"/>
    <dbReference type="SABIO-RK" id="G4NDL4"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904408">
        <property type="term" value="F:melatonin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061621">
        <property type="term" value="P:canonical glycolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00946">
        <property type="entry name" value="FBP_aldolase_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000013">
        <property type="entry name" value="Class II fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006628">
        <property type="entry name" value="PRK09197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559:SF0">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="267"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="288"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA49299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="360" mass="39776" checksum="DA22362D9C4ACCCC" modified="2011-12-14" version="1">MGVFSELGLKPGVLYGEEVYKLFEHAKKNVYAIPAINVTSSSTIIASLEAARDSKSPIILQMSQGGAAYFAGKGVSNTNQEASIAGAVAAAHFIRSIAPIYGVPVVLHTDHCAKKLLPWLDGMLDADEAFHKENGTPLFSSHMIDLSEEPRDWNIETTAKYLKRAAPMKQWLEMEIGLTGGEEDGVNNEDVDNNSLYTQPEDIFAIHQALSPISKYFSIAAGFGNVHGVYKPGNVRLHPELLDKHQKYVIEKLGCEEKKPIFFVFHGGSGSGDSEFQEAISYGVIKVNLDTDLQWAYLSGIRDYVTSKIEYLNSQVGNPDGADKPNKKYYDPRVWVREGEKTMKARIQQALKVFNAENTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDN7</accession>
    <name>G4NDN7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718059.1">
        <property type="nucleotide sequence ID" value="XM_003718011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDN7"/>
    <dbReference type="GeneID" id="12984009"/>
    <dbReference type="KEGG" id="mgr:MGG_17346"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17346"/>
    <dbReference type="HOGENOM" id="CLU_2543021_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDN7"/>
    <dbReference type="OrthoDB" id="10475480at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="83" mass="9386" checksum="223C329E733CB04C" modified="2011-12-14" version="1">MVADPVLVMWLEYMVEWVEGDVKNHRYGVSSSCRREWPQLERKRRSRGQGAAAAVRPQHAAKVGLVDGGVRRDLHRSAVFQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDN9</accession>
    <name>G4NDN9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mediator of RNA polymerase II transcription subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Mediator complex subunit 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED9</name>
        <name evidence="11" type="ORF">MGG_00900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718061.1">
        <property type="nucleotide sequence ID" value="XM_003718013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDN9"/>
    <dbReference type="SMR" id="G4NDN9"/>
    <dbReference type="STRING" id="242507.G4NDN9"/>
    <dbReference type="GeneID" id="2674394"/>
    <dbReference type="KEGG" id="mgr:MGG_00900"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00900"/>
    <dbReference type="eggNOG" id="ENOG502SW8C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097220_2_0_1"/>
    <dbReference type="InParanoid" id="G4NDN9"/>
    <dbReference type="OMA" id="IRIQKAH"/>
    <dbReference type="OrthoDB" id="5414694at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011425">
        <property type="entry name" value="Med9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07544">
        <property type="entry name" value="Med9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="95"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA48477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="147" mass="15300" checksum="5A34048627B9B688" modified="2011-12-14" version="1">MPAQQSQPPLALPPTLSPETLDALTELAAIVSRLRPPQSLPGGITVNTPGAAATPAAGIGIGGPSGATISIKDVPNATDTVKHKLQRARAQVKALPDMSRTVEEQRETIARLEETIRQQQEVLAALRSVDGAHGLDAADEGGDKMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEG9</accession>
    <name>G4NEG9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719030.1">
        <property type="nucleotide sequence ID" value="XM_003718982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEG9"/>
    <dbReference type="GeneID" id="12985128"/>
    <dbReference type="KEGG" id="mgr:MGG_17534"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17534"/>
    <dbReference type="HOGENOM" id="CLU_2776425_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEG9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="69" mass="7857" checksum="7EB056894CCBDD3C" modified="2011-12-14" version="1">MVEWRGAFGPVLLAKKAAKAVTDYLFEPSVSEIGRLKQKFAVEKAKTASRNLLWTYGTVRVRLWAFPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFV1</accession>
    <name>G4NFV1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_08705</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719275.1">
        <property type="nucleotide sequence ID" value="XM_003719227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFV1"/>
    <dbReference type="SMR" id="G4NFV1"/>
    <dbReference type="FunCoup" id="G4NFV1">
        <property type="interactions" value="962"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NFV1"/>
    <dbReference type="GeneID" id="2678930"/>
    <dbReference type="KEGG" id="mgr:MGG_08705"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08705"/>
    <dbReference type="eggNOG" id="KOG1541">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055194_0_2_1"/>
    <dbReference type="InParanoid" id="G4NFV1"/>
    <dbReference type="OMA" id="WIQEKKE"/>
    <dbReference type="OrthoDB" id="2877at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000017">
        <property type="entry name" value="probable 18S rRNA (Guanine-N(7))-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="9">
        <location>
            <begin position="52"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="10">
        <location>
            <begin position="212"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA46908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="279" mass="29981" checksum="6BFF258EF27767BC" modified="2011-12-14" version="1">MSRPEDTLAADVHYNDTEARKYTTSSRIQNIQAAMTRRALELLELTSPSLILDVGCGSGLSGEILTAEDPADGGPHTWIGMDVSPSMLDVALQRDVAGDLMLADIGQGVPFRAGSFDAAISISAIQWLCNAESSDTSPLGRLSRFFNGLYASLRRGGRAVCQFYPKNDTQRDMIAGAAKKAGFAAGLLEDDPDTKNKKVYLVLTVGGSAHDGSGGDITDVVKGLDNVDVLDVSRKPKAGRDMRKGGKAWIVKKKEQMERKGKVVKASSKYTGRKRKPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGZ3</accession>
    <name>G4NGZ3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hsp70-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03983</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FES1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719870.1">
        <property type="nucleotide sequence ID" value="XM_003719822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGZ3"/>
    <dbReference type="SMR" id="G4NGZ3"/>
    <dbReference type="FunCoup" id="G4NGZ3">
        <property type="interactions" value="198"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGZ3"/>
    <dbReference type="GeneID" id="2677356"/>
    <dbReference type="KEGG" id="mgr:MGG_03983"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03983"/>
    <dbReference type="eggNOG" id="KOG2160">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084507_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGZ3"/>
    <dbReference type="OMA" id="LKWSVEN"/>
    <dbReference type="OrthoDB" id="10250458at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000434">
        <property type="entry name" value="Hsp70 nucleotide exchange factor fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013918">
        <property type="entry name" value="Nucleotide_exch_fac_Fes1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08609">
        <property type="entry name" value="Fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Nucleotide exchange factor Fes1" evidence="8">
        <location>
            <begin position="6"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="7">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="217" mass="23384" checksum="1F4B66C7EA38001D" modified="2011-12-14" version="1">MGDKNLNALLKWSIENTNTDGSAPAAGADQQQELQRPDPEVLAALFGGPSEAELMKAAMDVITSTEPDVTLDNKLIAFDNFEQLIESLDNANNLSKLSLWTPLLGLLDSDHPDLRRMAAWCIGTAVQNNEPCQERLLALGGLPSLVKLATAEDQREDVRRKAVYALSSAGRNYQPAMDVIVEEVGKQGGKSDKVDATNMDAVDAVIDLLKAGIPKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHG8</accession>
    <name>G4NHG8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720045.1">
        <property type="nucleotide sequence ID" value="XM_003719997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHG8"/>
    <dbReference type="SMR" id="G4NHG8"/>
    <dbReference type="STRING" id="242507.G4NHG8"/>
    <dbReference type="GeneID" id="2677348"/>
    <dbReference type="KEGG" id="mgr:MGG_03846"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03846"/>
    <dbReference type="eggNOG" id="KOG2128">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009455_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHG8"/>
    <dbReference type="OMA" id="AYMITLN"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046580">
        <property type="term" value="P:negative regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05132">
        <property type="entry name" value="RasGAP_GAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF17">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="2">
        <location>
            <begin position="185"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="779" mass="89021" checksum="808BD79150A99D2D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHI5</accession>
    <name>G4NHI5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Averantin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_03830</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720062.1">
        <property type="nucleotide sequence ID" value="XM_003720014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHI5"/>
    <dbReference type="SMR" id="G4NHI5"/>
    <dbReference type="STRING" id="242507.G4NHI5"/>
    <dbReference type="GeneID" id="2677221"/>
    <dbReference type="KEGG" id="mgr:MGG_03830"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03830"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="InParanoid" id="G4NHI5"/>
    <dbReference type="OMA" id="MEQSTHI"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000047">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF29">
        <property type="entry name" value="BENZOATE-PARA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="501" mass="56160" checksum="5D2B51D0D0DA4D5A" modified="2011-12-14" version="1">MAAPMSAFTIGNLFMLLVVALGIISIYYGLLCIYNLYFHPLAKYPGPRLAAATHLWLMRAYLSGKAHRHIHEAHKRYGPVVRTTPDGLSYVDARQWKEIYGHQPSGRPEFSKQAFASAVFEEPTLHNADREYHGYVRRLFAHGFSEKALKGQESVLKEYVDWMFAGIERESRGGSRPVNVVNWYNYLTFDFIGFLTYGESFDCLRTSSLHDWIKLFISFGKLLIYGQVLLPIPRLLKIPAALLLIPSKLREDRKRASALQSEKIKHRLSIQPTITDFTTKMVEAYNNGKMSMNQLEGNSILLIGAGSETTATALSGLTWLLAQNPAVLAKLAAEVRSAFASTEQITSTGVNSCKYLLACVEEALRVYPPLAQPHYRIVPRGGASVGGDHLPAGVVVSVPKYAAARSPLNFHRPDDFCPERWLGGHDGEFAGDQRDASQPFSVGPRACIARNLAYLEVRLVIARLVWQYDIENATEGDWLGGQNLWHLWEKGPLWLRLKAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHS6</accession>
    <name>G4NHS6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Geranylgeranyl pyrophosphate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_09448</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720153.1">
        <property type="nucleotide sequence ID" value="XM_003720105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHS6"/>
    <dbReference type="SMR" id="G4NHS6"/>
    <dbReference type="STRING" id="242507.G4NHS6"/>
    <dbReference type="GeneID" id="2680394"/>
    <dbReference type="KEGG" id="mgr:MGG_09448"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09448"/>
    <dbReference type="eggNOG" id="KOG0777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_6_0_1"/>
    <dbReference type="InParanoid" id="G4NHS6"/>
    <dbReference type="OMA" id="CAGERHK"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046165">
        <property type="term" value="P:alcohol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF72">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G01210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA47786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="371" mass="40841" checksum="94DE4240CC5333E3" modified="2011-12-14" version="1">MSVAGTTTVPSEAPEPVQVVPDCSQSLTSDAIPSVLQAKDAKHINKTDYGSGVGRKGDVIQALVNVNLPSPTLEHVTAPFDYICSLKSKHVREKLIFSLHPWVPIARPELELVMSLVADIHNTSLMLDDIQDSSALRRSSPATHTVFGTPQTINSAVYFTVDTIQRASTSGNPELMQALTDGMKELLVGQGLDLVWTLEVTTPSLEEYLQMIDGKTGALFLMVTRLMGAFLPASAPKSPLDRLMLLLGRYFQIRDDYVNLVSTQYSDSRGFCTDLDEGKCSFMIVHAMSHAQPSARNILRNVLLQTRRAGCAGERHKELMFSILKEAGSFEYTAEMLGEMEKSLFAEVERIERTTGVKNPVLRELLDALRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="82" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIS8</accession>
    <name>G4NIS8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 14">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="3 14">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_17683</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the MCM family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 14"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719701.1">
        <property type="nucleotide sequence ID" value="XM_003719653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIS8"/>
    <dbReference type="SMR" id="G4NIS8"/>
    <dbReference type="FunCoup" id="G4NIS8">
        <property type="interactions" value="1041"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NIS8"/>
    <dbReference type="GeneID" id="12986150"/>
    <dbReference type="KEGG" id="mgr:MGG_17683"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17683"/>
    <dbReference type="eggNOG" id="KOG0480">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000995_3_1_1"/>
    <dbReference type="InParanoid" id="G4NIS8"/>
    <dbReference type="OMA" id="RHQQTDK"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071162">
        <property type="term" value="C:CMG complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033679">
        <property type="term" value="F:3'-5' DNA/RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006267">
        <property type="term" value="P:pre-replicative complex assembly involved in nuclear cell cycle DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.870:FF:000002">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000009">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000115">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 14" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="16">
        <location>
            <begin position="472"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="789"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
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        <location>
            <begin position="179"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="789"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="830"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073495"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA47334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="953" mass="104554" checksum="9447934CBD1E9F7B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJ95</accession>
    <name>G4NJ95_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">MGG_15014</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <dbReference type="AlphaFoldDB" id="G4NJ95"/>
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    <dbReference type="KEGG" id="mgr:MGG_15014"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15014"/>
    <dbReference type="HOGENOM" id="CLU_1594880_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJ95"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="167" mass="17824" checksum="6950FE0BE154E52D" modified="2011-12-14" version="1">MFGCAQTSANGNILVKVVAGFPSIDGGRSEPKLAQSYTPVHRNKSRQPCIKEIPGGSRLSPRFSCNLPMAGVHVADEAVVGGPTSRSQPSAQLLMASMKCNMGPTGKDLKRTTSEERLPLAIVGIRGRWAALPGRRSSSLMPLMHQRSRRGSTTLQNHGVLYDTGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJK9</accession>
    <name>G4NJK9_PYRO7</name>
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        <submittedName>
            <fullName evidence="4">Ser/Thr protein phosphatase family protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">MGG_12647</name>
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    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721168.1">
        <property type="nucleotide sequence ID" value="XM_003721120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJK9"/>
    <dbReference type="SMR" id="G4NJK9"/>
    <dbReference type="FunCoup" id="G4NJK9">
        <property type="interactions" value="28"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NJK9"/>
    <dbReference type="GeneID" id="5050520"/>
    <dbReference type="KEGG" id="mgr:MGG_12647"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12647"/>
    <dbReference type="eggNOG" id="KOG0371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023125_0_2_1"/>
    <dbReference type="InParanoid" id="G4NJK9"/>
    <dbReference type="OMA" id="PFSHGDQ"/>
    <dbReference type="OrthoDB" id="10267127at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006798">
        <property type="term" value="P:polyphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00144">
        <property type="entry name" value="MPP_PPP_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050126">
        <property type="entry name" value="Ap4A_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850:SF4">
        <property type="entry name" value="ZINC-DEPENDENT ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="179"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="541" mass="58655" checksum="F69A89479CC2B053" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJP4</accession>
    <name>G4NJP4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_02595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721203.1">
        <property type="nucleotide sequence ID" value="XM_003721155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJP4"/>
    <dbReference type="GeneID" id="2682335"/>
    <dbReference type="KEGG" id="mgr:MGG_02595"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02595"/>
    <dbReference type="eggNOG" id="ENOG502QZJZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010508_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJP4"/>
    <dbReference type="OMA" id="ETYIAIM"/>
    <dbReference type="OrthoDB" id="5104314at2759"/>
    <dbReference type="PHI-base" id="PHI:5596"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="689"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="467"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA46460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="771" mass="83749" checksum="75E3D69AB6698011" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKG9</accession>
    <name>G4NKG9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_14010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721346.1">
        <property type="nucleotide sequence ID" value="XM_003721298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKG9"/>
    <dbReference type="SMR" id="G4NKG9"/>
    <dbReference type="STRING" id="242507.G4NKG9"/>
    <dbReference type="GeneID" id="5051372"/>
    <dbReference type="KEGG" id="mgr:MGG_14010"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14010"/>
    <dbReference type="eggNOG" id="ENOG502SRF2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056597_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKG9"/>
    <dbReference type="OMA" id="ADEFMAS"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="420"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="148"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="247"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA46603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="466" mass="50089" checksum="CDB4D11DE98F7C69" modified="2011-12-14" version="1">MSAPSMNNNGGNACNNNNSRAQQISYADLMKPDEDWRVLPDAAERRRIQNRLAQRAYRRNMRDRTKELEKLKKELATLKKDPVGQVSPRMSPPQQPVATMVSAPSDDFIFDGTMSSDMGMASAWTEPFPSTQFEASMNMESYFPQVPEMARPGSKRRRTSSSEGHMAPRPGSGGLSVGAIHGHQRSRSHTPISSPPMVNAALMQDGLATPPMAEFFPSPCNFDLGSDMTNQVSLPQTDDIQPFTLDGFTNDCNGDSNNNNNTASSSLDQGLWTPPMTGSLYGSFLTPPTQHQDGASSPPNCWQNSTPSTVRSENMGRSRSCSSASNVSPFSAATSQFSSPALSATAKAVQPSGLNLNVFDATSHDNMSMLPTIDGNIITTPITNQSQSSLLHLAVSGGHLSVLKLLLQSCDIPINTRDAKGYTALQRAVFAGKMEMVTLLIEHGADFSAGRQDDGAEAAAEHAAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLK1</accession>
    <name>G4NLK1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_02922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720797.1">
        <property type="nucleotide sequence ID" value="XM_003720749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLK1"/>
    <dbReference type="STRING" id="242507.G4NLK1"/>
    <dbReference type="GeneID" id="2682475"/>
    <dbReference type="KEGG" id="mgr:MGG_02922"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02922"/>
    <dbReference type="eggNOG" id="ENOG502RAQ3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_737844_0_0_1"/>
    <dbReference type="InParanoid" id="G4NLK1"/>
    <dbReference type="OMA" id="HECEDIC"/>
    <dbReference type="OrthoDB" id="5362630at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052973">
        <property type="entry name" value="Fungal_sec-metab_reg_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392:SF3">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35392">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="365" mass="41149" checksum="EBB44A3AF833E4D2" modified="2011-12-14" version="1">MGEASFQPNLLDLNFLRPGSLSLTSRGIEEEPTWQDSEVKTIEISLGLCPQPMSFQVRRFVPGENDALSRTWIDPGGRSRSTPLAPYAVADIPEAVSHIKQYIRNNSNCFVEAVRHSHPAVQLVYSCVADWLSELQHGNDSPKSQQLKLLEQYSQLWFGIRNTVGSSWLCGYETLGMEPIHEEGYPLHGKISTPRQVVQTVGCLLDHATRPLQAQFLQSLKAMLCADGNPSTLYTLFLVVFVLLHECEDICKDRERYARQNCMKVRFSLPEYVVDLHKSARHLVTQWLAYATKAGVDFSSKQKLECSLGFLSNSIRQAIVQSYAMVIDEACPVIRASPETWTQDLCFVSHMFGVPWEKNAMYTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHE4</accession>
    <name>G5EHE4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g658</name>
        <name evidence="3" type="ORF">MGG_17937</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720831.1">
        <property type="nucleotide sequence ID" value="XM_003720783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHE4"/>
    <dbReference type="GeneID" id="12984811"/>
    <dbReference type="KEGG" id="mgr:MGG_17937"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17937"/>
    <dbReference type="HOGENOM" id="CLU_189326_0_0_1"/>
    <dbReference type="OMA" id="QRCENCT"/>
    <dbReference type="OrthoDB" id="4843205at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="76" mass="8626" checksum="5C60A16BA9D7E5ED" modified="2011-12-14" version="1">MGSGAPSGSHRHRSHGSSSKEGKDKKNKTKTTHVWYCCHCNRGPLNVDIDDYCPYHDCGYQRCENCTYDSFKQPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHI1</accession>
    <name>G5EHI1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g222</name>
        <name evidence="2" type="ORF">MGG_18042</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721288.1">
        <property type="nucleotide sequence ID" value="XM_003721240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHI1"/>
    <dbReference type="GeneID" id="12985854"/>
    <dbReference type="KEGG" id="mgr:MGG_18042"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18042"/>
    <dbReference type="HOGENOM" id="CLU_1796854_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ70815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="144" mass="15965" checksum="73DE394814E8E416" modified="2011-12-14" version="1">MSCSAQLSESIFISLILGVHVEDEKGRMILPSSKELPRMTQLPDRIVNLGNESAKFSRSVAFPSQHELYMTNVPSVCFFSCLERHRSVLCCQVEGCKVNSHLLIHPMHALPIEADAFCRARWQDRTGMSSCHGGQGGLECGGTW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2026-01-28" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI58</accession>
    <name>HRR25_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine/threonine protein kinase HRR25</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Casein kinase I homolog HRR25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HRR25</name>
        <name type="ORF">MGCH7_ch7g585</name>
        <name type="ORF">MGG_02829</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2019" name="Virulence" volume="10" first="719" last="733">
            <title>The casein kinase MoYck1 regulates development, autophagy, and virulence in the rice blast fungus.</title>
            <authorList>
                <person name="Shi H.B."/>
                <person name="Chen N."/>
                <person name="Zhu X.M."/>
                <person name="Su Z.Z."/>
                <person name="Wang J.Y."/>
                <person name="Lu J.P."/>
                <person name="Liu X.H."/>
                <person name="Lin F.C."/>
            </authorList>
            <dbReference type="PubMed" id="31392921"/>
            <dbReference type="DOI" id="10.1080/21505594.2019.1649588"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Serine/threonine protein kinase that is essential for viability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="2">Impairs viability.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720909.1">
        <property type="nucleotide sequence ID" value="XM_003720861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI58"/>
    <dbReference type="SMR" id="G5EI58"/>
    <dbReference type="FunCoup" id="G5EI58">
        <property type="interactions" value="957"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EI58"/>
    <dbReference type="EnsemblFungi" id="MGG_02829T0">
        <property type="protein sequence ID" value="MGG_02829T0"/>
        <property type="gene ID" value="MGG_02829"/>
    </dbReference>
    <dbReference type="GeneID" id="2682382"/>
    <dbReference type="KEGG" id="mgr:MGG_02829"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02829"/>
    <dbReference type="eggNOG" id="KOG1164">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019279_2_7_1"/>
    <dbReference type="OMA" id="IFDWTFL"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000159">
        <property type="entry name" value="Casein kinase I hhp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000463449" description="Serine/threonine protein kinase HRR25">
        <location>
            <begin position="1"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="18"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="31392921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="3">
        <source>
            <dbReference type="PubMed" id="31392921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <evidence type="ECO:0000305" key="5">
        <source>
            <dbReference type="PubMed" id="31392921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EAQ71178.1"/>
        </source>
    </evidence>
    <sequence length="356" mass="40925" checksum="F218F578D2E2158E" modified="2011-12-14" version="1">MTTMDLRVGNKYRIGRKIGSGSFGDIYLGTNIISGEEIAIKLESVKAKHPQLEYEARVYKSLAGGVGIPFVRWFGTECDYNAMVLDLLGPSLEDLFNFCNRKFSLKTVLLLADQLISRIEYIHAKSFIHRDIKPDNFLMGIGKRGNQVNVIDFGLAKKYRDPKTHFHIPYRENKNLTGTARYASINTHLGVEQSRRDDMESLGYVMLYFCRGSLPWQGLKAATKKQKYDRIMEKKMTTPTEVLCRGFPNEFAIYLNYTRSLRFDDKPDYSYLRKIFRDLFVREGFQYDYVFDWTVYKYQKNAQAIRQGEDKQGREDPSQQAQPGTVAQSSRPRNKNLIAGEDTPNTRGAVGGSDRM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2013-09-18" modified="2025-06-18" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>P0CT15</accession>
    <accession>G4MYU7</accession>
    <accession>Q5EMX3</accession>
    <name>RS29_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small ribosomal subunit protein uS14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>40S ribosomal protein S29</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">RPS29</name>
        <name type="ORF">MGG_08163</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715133.1">
        <property type="nucleotide sequence ID" value="XM_003715085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P0CT15"/>
    <dbReference type="SMR" id="P0CT15"/>
    <dbReference type="FunCoup" id="P0CT15">
        <property type="interactions" value="736"/>
    </dbReference>
    <dbReference type="STRING" id="242507.P0CT15"/>
    <dbReference type="EnsemblFungi" id="MGG_08163T0">
        <property type="protein sequence ID" value="MGG_08163T0"/>
        <property type="gene ID" value="MGG_08163"/>
    </dbReference>
    <dbReference type="GeneID" id="12985565"/>
    <dbReference type="KEGG" id="mgr:MGG_08163"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08163"/>
    <dbReference type="eggNOG" id="KOG3506">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_177289_1_1_1"/>
    <dbReference type="InParanoid" id="P0CT15"/>
    <dbReference type="OMA" id="HCFREIA"/>
    <dbReference type="OrthoDB" id="10252683at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.830.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000268814" description="Small ribosomal subunit protein uS14">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="56" mass="6496" checksum="426A0965F88844C9" modified="2013-09-18" version="1">MSHDSVWNSRPRTYGKGARSCRVCTHRAGLIRKYGLDICRQCFREKAADIGFVKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4I6</accession>
    <name>A0A151V4I6_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="4">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_09124</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="4"/>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30476.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_016990453.1"/>
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    <dbReference type="STRING" id="242507.A0A151V4I6"/>
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    <dbReference type="KEGG" id="mgr:MGG_09124"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09124"/>
    <dbReference type="eggNOG" id="KOG2277">
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    </dbReference>
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    <dbReference type="OrthoDB" id="2274644at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="term" value="P:RNA 3'-end processing"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="NT_PAP_TUTase"/>
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    </dbReference>
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        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MTPAP-like_central"/>
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    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
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        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF113">
        <property type="entry name" value="POLY(A) RNA POLYMERASE CID11"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="MTPAP-like_central"/>
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    </dbReference>
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        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="10">
        <location>
            <begin position="293"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="9">
        <location>
            <begin position="514"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="75"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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    <feature type="region of interest" description="Disordered" evidence="8">
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    <feature type="region of interest" description="Disordered" evidence="8">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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            <begin position="1099"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1204"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1240"/>
            <end position="1339"/>
        </location>
    </feature>
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        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="151"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="745"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="799"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="832"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="862"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1045"/>
            <end position="1056"/>
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    </feature>
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        <location>
            <begin position="1057"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1240"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1315"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1330"/>
            <end position="1339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KYQ30476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1339" mass="145496" checksum="5D373D192720177E" modified="2016-06-08" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-02-10" modified="2025-04-09" version="92" xmlns="https://uniprot.org/uniprot">
    <accession>A4RFH6</accession>
    <accession>G4NCR3</accession>
    <name>EIF3D_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Eukaryotic translation initiation factor 3 subunit D</fullName>
            <shortName evidence="2">eIF3d</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ORF">MGG_00341</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-3 subunit D family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718741.1">
        <property type="nucleotide sequence ID" value="XM_003718693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RFH6"/>
    <dbReference type="SMR" id="A4RFH6"/>
    <dbReference type="STRING" id="242507.A4RFH6"/>
    <dbReference type="EnsemblFungi" id="MGG_00341T0">
        <property type="protein sequence ID" value="MGG_00341T0"/>
        <property type="gene ID" value="MGG_00341"/>
    </dbReference>
    <dbReference type="GeneID" id="2674990"/>
    <dbReference type="KEGG" id="mgr:MGG_00341"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00341"/>
    <dbReference type="eggNOG" id="KOG2479">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024521_2_0_1"/>
    <dbReference type="InParanoid" id="A4RFH6"/>
    <dbReference type="OMA" id="FMDKRDN"/>
    <dbReference type="OrthoDB" id="16538at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071540">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3e"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098808">
        <property type="term" value="F:mRNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002191">
        <property type="term" value="P:cap-dependent translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03003">
        <property type="entry name" value="eIF3d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007783">
        <property type="entry name" value="eIF3d"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05091">
        <property type="entry name" value="eIF-3_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016281">
        <property type="entry name" value="EIF-3_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0396">Initiation factor</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <feature type="chain" id="PRO_0000364176" description="Eukaryotic translation initiation factor 3 subunit D">
        <location>
            <begin position="1"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA gate" evidence="1">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="556"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="K7IM66"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="573" mass="63208" checksum="D1075B79AA7734DC" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKP2</accession>
    <name>G4MKP2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase family domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709344.1">
        <property type="nucleotide sequence ID" value="XM_003709296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKP2"/>
    <dbReference type="SMR" id="G4MKP2"/>
    <dbReference type="STRING" id="242507.G4MKP2"/>
    <dbReference type="GeneID" id="2684815"/>
    <dbReference type="KEGG" id="mgr:MGG_06642"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06642"/>
    <dbReference type="eggNOG" id="ENOG502RXMD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015562_1_0_1"/>
    <dbReference type="InParanoid" id="G4MKP2"/>
    <dbReference type="OMA" id="PNGCDHG"/>
    <dbReference type="OrthoDB" id="10261749at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052765">
        <property type="entry name" value="PGM-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46192">
        <property type="entry name" value="BROAD-RANGE ACID PHOSPHATASE DET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="633" mass="70242" checksum="03366EFAB20DCC99" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKX9</accession>
    <name>G4MKX9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Meiotically up-regulated 80 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710226.1">
        <property type="nucleotide sequence ID" value="XM_003710178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKX9"/>
    <dbReference type="SMR" id="G4MKX9"/>
    <dbReference type="STRING" id="242507.G4MKX9"/>
    <dbReference type="GeneID" id="12985380"/>
    <dbReference type="KEGG" id="mgr:MGG_16341"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16341"/>
    <dbReference type="eggNOG" id="ENOG502RYK1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030504_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKX9"/>
    <dbReference type="OMA" id="QVWRMLT"/>
    <dbReference type="OrthoDB" id="244495at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="40405" checksum="6D8813C703ABB968" modified="2011-12-14" version="1">MPGGVCAVLDYDVEMMAEYVASMATRLTLGNVPVSPPFQKFVSQILTSTRLPSTTILLGMNYMAKRINSMAQRQGEPPKFNDGQVWRMLTTAFLLGSKFLDDNTFQNKSWSEVSAIPVQELNTLEMEWLAAMDWQLYVNLDSTADYTAWLTSWAQWKEDKERQKAAERAAARERHMSAVPRIDTDVFAFHNPAWRQQQVAEYERLQSLNQKRTELSPPSSVSGHSAWYSERPVTWGHPLTPPDSGYGTPDYSINSAASHSAQYNEWFARGIAFNNYGPSRQAAYQYPNSHRNSYQNVCHSARQPASAHPGYYGCNNGYHNIWDANGMDCTSCTSSTHHKSMHHFGMPHTHGFGQPVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML50</accession>
    <name>G4ML50_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">General transcription and DNA repair factor IIH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_06690</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the GTF2H2 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA56786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003709398.1">
        <property type="nucleotide sequence ID" value="XM_003709350.1"/>
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    <dbReference type="SMR" id="G4ML50"/>
    <dbReference type="FunCoup" id="G4ML50">
        <property type="interactions" value="1010"/>
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    <dbReference type="STRING" id="242507.G4ML50"/>
    <dbReference type="GeneID" id="2684863"/>
    <dbReference type="KEGG" id="mgr:MGG_06690"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06690"/>
    <dbReference type="eggNOG" id="KOG2807">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_028556_2_0_1"/>
    <dbReference type="InParanoid" id="G4ML50"/>
    <dbReference type="OMA" id="INWVEVP"/>
    <dbReference type="OrthoDB" id="284275at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
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    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0006289">
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    <dbReference type="GO" id="GO:0006357">
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    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
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    </dbReference>
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        <property type="entry name" value="von Willebrand factor, type A domain"/>
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        <property type="entry name" value="C1-like_sf"/>
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        <property type="entry name" value="Ssl1-like"/>
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    <dbReference type="InterPro" id="IPR004595">
        <property type="entry name" value="TFIIH_C1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012170">
        <property type="entry name" value="TFIIH_SSL1/p44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
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    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00622">
        <property type="entry name" value="ssl1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07975">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015919">
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    </dbReference>
    <dbReference type="SMART" id="SM01047">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
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    </dbReference>
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    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VWFA" evidence="14">
        <location>
            <begin position="99"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="12">
        <location>
            <begin position="341"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="406"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="494"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="EMBL" id="EHA56786.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="516" mass="56031" checksum="892BC09B9BB01193" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLE3</accession>
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        <submittedName>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003710237.1"/>
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    <dbReference type="HOGENOM" id="CLU_1366477_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLE3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="200" mass="21923" checksum="FD075FBCC672A0BA" modified="2011-12-14" version="1">MLELVPAQCQITTARAPRRLQKPQNLVPVCPCARVPLTAISGDSVPAHASSAAQDGPLVEWSRDLNEIWTFGWKTHFTTYLTSALAARGTEGIPTIYARNHDDQTLVPAKRRRDKTLKVSVTGSTGQHGGVKIKQAEKETWNAAARQATNAMVQPASRLSIAPTKAEKPAARTWQSTSPRDSRQVRTVFTCMRMAVTPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLZ9</accession>
    <name>G4MLZ9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">C6 zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06778</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709496.1">
        <property type="nucleotide sequence ID" value="XM_003709448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLZ9"/>
    <dbReference type="SMR" id="G4MLZ9"/>
    <dbReference type="STRING" id="242507.G4MLZ9"/>
    <dbReference type="GeneID" id="2684951"/>
    <dbReference type="KEGG" id="mgr:MGG_06778"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06778"/>
    <dbReference type="eggNOG" id="ENOG502QTCC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008719_5_1_1"/>
    <dbReference type="InParanoid" id="G4MLZ9"/>
    <dbReference type="OMA" id="HHHGAWT"/>
    <dbReference type="OrthoDB" id="415590at2759"/>
    <dbReference type="PHI-base" id="PHI:5633"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="110"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="724" mass="79162" checksum="626072AD04094B48" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMH6</accession>
    <name>G4MMH6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06846</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709566.1">
        <property type="nucleotide sequence ID" value="XM_003709518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMH6"/>
    <dbReference type="GeneID" id="2685019"/>
    <dbReference type="KEGG" id="mgr:MGG_06846"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06846"/>
    <dbReference type="eggNOG" id="ENOG502S4IP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1332151_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMH6"/>
    <dbReference type="OMA" id="YPSWNAT"/>
    <dbReference type="OrthoDB" id="5242623at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465124" evidence="2">
        <location>
            <begin position="24"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="206" mass="20974" checksum="CDD06C13FDCC14DA" modified="2011-12-14" version="1">MHFRNLPVSLLLALLDFGTLCPGLPLNSQPQDQGQGQALGPRDPKVTYTVVPIDGSLPTPSPGSGNGNSPGRPGPGDGNQAPPGVTVTVEKTMPPTTVTSIVPANTVVVTHTIVSLSTVTVTESVVEVSTTTQVAASSTAASSSQTTSASPDPTSTSADKSSSTTTATAESSPATTDSAPSSTRQPDDGQWWSQKYPSWNATNTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNV0</accession>
    <name>G4MNV0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flocculation suppression protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_06971</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709719.1">
        <property type="nucleotide sequence ID" value="XM_003709671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNV0"/>
    <dbReference type="SMR" id="G4MNV0"/>
    <dbReference type="STRING" id="242507.G4MNV0"/>
    <dbReference type="GeneID" id="2685144"/>
    <dbReference type="KEGG" id="mgr:MGG_06971"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06971"/>
    <dbReference type="eggNOG" id="KOG0627">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031225_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNV0"/>
    <dbReference type="OMA" id="SALWEFK"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="PHI-base" id="PHI:2178"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000229">
        <property type="entry name" value="HSF-type DNA-binding domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF396">
        <property type="entry name" value="FLOCCULATION SUPPRESSION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="6">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="361"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="458"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="464"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="535"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="579"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA57107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="600" mass="65999" checksum="2298363B9B81B4F1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNZ4</accession>
    <name>G4MNZ4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710555.1">
        <property type="nucleotide sequence ID" value="XM_003710507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNZ4"/>
    <dbReference type="GeneID" id="12986374"/>
    <dbReference type="KEGG" id="mgr:MGG_16437"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16437"/>
    <dbReference type="HOGENOM" id="CLU_2606491_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNZ4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="79" mass="8326" checksum="7C40A5DA669B07CF" modified="2011-12-14" version="1">MPYNTAPPSAKPPSATPEFGSLSVVVLINAVMGIDRGRTGSFGPEIPMLQSISLPMRSGSCCLPGFLLEIDTKLSHLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQN4</accession>
    <name>G4MQN4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial</fullName>
            <ecNumber evidence="11">1.14.15.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">2-methoxy-6-polyprenolphenol 4-hydroxylase</fullName>
            <ecNumber evidence="11">1.14.15.46</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">COQ6</name>
        <name evidence="13" type="ORF">MGG_11732</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-polyprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid. Also acts downstream of coq4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-polyprenyl)phenol to 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to coq6 from NADPH via a ferredoxin/ferredoxin reductase system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2-methoxy-6-(all-trans-polyprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:81183"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10858"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="ChEBI" id="CHEBI:84166"/>
            <dbReference type="EC" id="1.14.15.46"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:81195"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10930"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:64694"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="1.14.15.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.45" evidence="11"/>
    <dbReference type="EC" id="1.14.15.46" evidence="11"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709933.1">
        <property type="nucleotide sequence ID" value="XM_003709885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQN4"/>
    <dbReference type="SMR" id="G4MQN4"/>
    <dbReference type="FunCoup" id="G4MQN4">
        <property type="interactions" value="407"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MQN4"/>
    <dbReference type="GeneID" id="2680210"/>
    <dbReference type="KEGG" id="mgr:MGG_11732"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11732"/>
    <dbReference type="eggNOG" id="KOG3855">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_8_0_1"/>
    <dbReference type="InParanoid" id="G4MQN4"/>
    <dbReference type="OMA" id="VKQMQVW"/>
    <dbReference type="OrthoDB" id="683240at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120538">
        <property type="term" value="F:2-methoxy-6-polyprenolphenol 4-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106364">
        <property type="term" value="F:4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000021">
        <property type="entry name" value="Ubiquinone biosynthesis monooxygenase COQ6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000245">
        <property type="entry name" value="Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03193">
        <property type="entry name" value="COQ6_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051205">
        <property type="entry name" value="UbiH/COQ6_monooxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000689">
        <property type="entry name" value="UbQ_mOase_COQ6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="3 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="40"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="12">
        <location>
            <begin position="357"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA57321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="496" mass="53488" checksum="996B456A0F529E0D" modified="2011-12-14" version="1">MLSRPSTTRYICRRCNDVVKRSRTAARSYASSAGAKPDIYDVVCVGGGPAGLSLLTALRANPATAGLRIALVEAQDLSKLRNWSLPPNRYSNRCSSLTPSSAHFLDSIGAWSRLDRQRVQAYQEMQVWDGVTGARIEFDWAGTAEAARGNTIAYMVENLNLTSGLLRRLEELGGVDVFDNARVEDIALGKDTEDMDLSEWPVVSLAGGRQLFARLLVGADGANSPVRSFAGIDAKGWDYGRHGVVATLRLEDDVAAHDSMYRVAYQRFLPSGPIASLPMPGNYSTLVWSTTPAYAALLKSLSPADFTAMVNAAFRLSPVDLEYMHTIPSGQADELAWRLQHATIDAPPSPRALPAPVVEVQEGSVASFPLRMRHADTYIGERVALVGDAAHTVHPLAGQGLNAGQGDVESLSRTIAEAVAHGQDLGTRMSLEPYEAERYVANHVILGVCDKLHKLYSVGSGPLVPLRSLGLNAVNAAKPLKNFFMNQAAGNGFKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRG3</accession>
    <name>G4MRG3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709202.1">
        <property type="nucleotide sequence ID" value="XM_003709154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRG3"/>
    <dbReference type="FunCoup" id="G4MRG3">
        <property type="interactions" value="48"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRG3"/>
    <dbReference type="GeneID" id="2681513"/>
    <dbReference type="KEGG" id="mgr:MGG_02416"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02416"/>
    <dbReference type="eggNOG" id="KOG4453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031477_2_0_1"/>
    <dbReference type="InParanoid" id="G4MRG3"/>
    <dbReference type="OMA" id="NYWREMS"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037997">
        <property type="entry name" value="Dgk1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303">
        <property type="entry name" value="CTP-DEPENDENT DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31303:SF1">
        <property type="entry name" value="CTP-DEPENDENT DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="484" mass="52693" checksum="E4301F9D5266390B" modified="2011-12-14" version="1">MLHHPVAQTQAILRHQQAVFDATATSPRASRKDKYLAAEASTWPLTLFQRARALAGLIALPPLPPFALDVIDGETTGAMPSTRRLPTTRVISPSPTPSEIDAQSPSATSTSQDTSYFAPVTRSAARKRLATPQPVEEHINEDEEENNPDLRRARTRSRSPMDHQRIKPLSSTSTSNSKSKTSSGSKQASTVNGQINGNGKSVEPNGHLKPAAAMSTWDTWRETWSRSPSPLGLIPIHRHWRTFVHKHEVPRKLLHVSIGFLVVWLYLSGTQASSVTPWLMALLVPITAVDLLRHHHSGFNRLYVKVLGALMRESEFAGYNGVIFYLLGAWTVLYFFPKDVGVVGTLLLSWCDTAASTFGRLYGAYTPRIRRGKSLAGSTAAFIVGVATAGAFWGWLRPTYGPFQGDDAFMFTGSLALPQAVCEAVGVSREAATITGPLALGVMSLWSGFVASASEVVDVFGWDDNLTIPVLSGAFIWGFLKVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRI9</accession>
    <name>G4MRI9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-taxilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_11907</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709228.1">
        <property type="nucleotide sequence ID" value="XM_003709180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRI9"/>
    <dbReference type="SMR" id="G4MRI9"/>
    <dbReference type="STRING" id="242507.G4MRI9"/>
    <dbReference type="GeneID" id="5049699"/>
    <dbReference type="KEGG" id="mgr:MGG_11907"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11907"/>
    <dbReference type="eggNOG" id="KOG1850">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029275_2_0_1"/>
    <dbReference type="InParanoid" id="G4MRI9"/>
    <dbReference type="OMA" id="VQYNMAR"/>
    <dbReference type="OrthoDB" id="425555at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="381"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="403"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="53038" checksum="FBE2D9BFAB177A6F" modified="2011-12-14" version="1">MSAVNSATTQTAAPPRPAAMANGTSPSAVPVPAAAAAAPPQLNKKTKKKALDSNEASKLVAARISQLELDQAGDKEQEIEIEREVKKANRELNSQTAKMDNLQKIDHLTKRCSDLLADMKRHERESLKNKKRGDQLQKEKDQSRTELTKTVGLKEKLEKLCRELQKENNKLKSENKAYADKQLRDQNSWDEKFLGLLQRLDDYQSEKDNPKKQMVDMELDELFRQRFKTLIEQYELRDLHFHSLMRTKELEVQYNMARYEAEKKRAEAEVGRSRQLNAQIQTFSKTEGELRTQLNVYVDKFKQVEDTLNNSNDLFLTFRKEMEEMSKKSKKLEKENESLKRKHEAMNQNIFKMADERTKNLKELEELRKKTEKLTSIITQMQQQGRGIAPSGLANSVEPCYPEGEEEGDGEESEYEEEYEDVSEEDGEYYDEDLTEEEAQPEPQKFGPERPPPPPVANGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRR3</accession>
    <name>G4MRR3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710890.1">
        <property type="nucleotide sequence ID" value="XM_003710842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRR3"/>
    <dbReference type="GeneID" id="12986855"/>
    <dbReference type="KEGG" id="mgr:MGG_15302"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15302"/>
    <dbReference type="HOGENOM" id="CLU_2250649_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRR3"/>
    <dbReference type="OrthoDB" id="10328046at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="104" mass="11341" checksum="5D8FD57D03CF4DB3" modified="2011-12-14" version="1">MPVCRFGHVKSSPKPPRQRHPCSGASITDSAVGDLNPDTRHPVLNTSGFEQADTGSNSRLEGLCIPGLDWSRLPEAPRYSCGGLKSPMLDPRFVGNERRLRKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRZ2</accession>
    <name>G4MRZ2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
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                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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            <end position="334"/>
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            <end position="193"/>
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        </location>
    </feature>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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        <property type="protein sequence ID" value="EHA57521.1"/>
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        <property type="nucleotide sequence ID" value="XM_003710085.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_10523"/>
    <dbReference type="eggNOG" id="ENOG502RZJP">
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</entry>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Jeong J.S."/>
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                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <dbReference type="EMBL" id="EHA54585.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT14</accession>
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    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="eggNOG" id="KOG3293">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="InParanoid" id="G4MT14"/>
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        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01723">
        <property type="entry name" value="LSm4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Lsm4"/>
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    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
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    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
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    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
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    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="64"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="106"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU365049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA54673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="121" mass="13331" checksum="C8624C6BB26CD895" modified="2011-12-14" version="1">MMVELKNGETLNGHLVQCDTWMNLTLREVVQTSPDGDKFMRLPEIYVKGNNIKYLRVPDEVIDQVKEQQQQHQQQHQQHGQQGGFRGGRGGGSRGDHRGGGDRGRGGRGRGAGRGRGRGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT40</accession>
    <name>G4MT40_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_12348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715312.1">
        <property type="nucleotide sequence ID" value="XM_003715264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT40"/>
    <dbReference type="GeneID" id="5050943"/>
    <dbReference type="KEGG" id="mgr:MGG_12348"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12348"/>
    <dbReference type="HOGENOM" id="CLU_1982017_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT40"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="126" mass="13957" checksum="CA2E8A4E652DCF61" modified="2011-12-14" version="1">MGSASGKLKGLCSKQKPYFANLTSLNCLALKSGVNLSDRLTIIDIYADEKMGEPSAFVTKAIIRKKLPIFIRRLLHNQKENENGGRNTIREELVGCTIVMVRGSSLVQGLESWDETVARQSRATFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT41</accession>
    <name>G4MT41_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_12349</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA55506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003715265.1"/>
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    <dbReference type="PHI-base" id="PHI:3315"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
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    </dbReference>
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        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
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    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="229"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="265"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="497"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="595"/>
            <end position="659"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="10"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="48"/>
            <end position="59"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="7">
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            <begin position="98"/>
            <end position="124"/>
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    </feature>
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            <begin position="133"/>
            <end position="150"/>
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        <location>
            <begin position="171"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="186"/>
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        <location>
            <begin position="512"/>
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        <location>
            <begin position="522"/>
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        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="609"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="659" mass="72657" checksum="85607480EAD52559" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT67</accession>
    <name>G4MT67_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CT20 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07142</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF7 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA55532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715339.1">
        <property type="nucleotide sequence ID" value="XM_003715291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT67"/>
    <dbReference type="STRING" id="242507.G4MT67"/>
    <dbReference type="GeneID" id="2683264"/>
    <dbReference type="KEGG" id="mgr:MGG_07142"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07142"/>
    <dbReference type="eggNOG" id="KOG4051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050564_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT67"/>
    <dbReference type="OMA" id="QHTRIPY"/>
    <dbReference type="OrthoDB" id="5595141at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012423">
        <property type="entry name" value="Eaf7/MRGBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581">
        <property type="entry name" value="MRG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581:SF5">
        <property type="entry name" value="MRG_MORF4L-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07904">
        <property type="entry name" value="Eaf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="149"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="34941" checksum="2BE92FD38DE8F252" modified="2011-12-14" version="1">MPPRKRGRSSVATTAAAAQEDDAMEVDTPQAASTPTTTTAPTTHPTVDLTSPWTDDQVASLFKGIIRYKPAGMHKHFRMIAISEHLRKHGFDPNVLKHTRIPGIWEKLGTFYNIDVIDDRENNILDDESLEKRWLEFRLPVGEYHELQDQRRYRAPGDDDTPATSPAQWDPDESPDSQPNQKAVAPAAPSTKRKRAERLSKARSSTVEDSDEEPTTPPKTARGGRGGRRRVSTRVKADNNNNEEEEAEEEEQEDEDGEDDQDGSDDDAAENSSEAEGSASEEAEATASTAKSTRGARGRGGRGGRGRGRGRGRRGRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTM1</accession>
    <name>G4MTM1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715386.1">
        <property type="nucleotide sequence ID" value="XM_003715338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTM1"/>
    <dbReference type="STRING" id="242507.G4MTM1"/>
    <dbReference type="GeneID" id="2683165"/>
    <dbReference type="KEGG" id="mgr:MGG_07182"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07182"/>
    <dbReference type="eggNOG" id="KOG4253">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_044758_1_0_1"/>
    <dbReference type="InParanoid" id="G4MTM1"/>
    <dbReference type="OMA" id="YFYYALP"/>
    <dbReference type="OrthoDB" id="4218123at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39470:SF1">
        <property type="entry name" value="CHORISMATE SYNTHASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39470">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="357" mass="39415" checksum="E60B138196545EA0" modified="2011-12-14" version="1">MVSISWGTIKSLLLFFGPFLLPKMISYYRNLRASSAQSNQPIRPPPPGAQRVIILLCVVAIVFIAKTLPTLSPENVFVLTDSRIQIPTDVLFNRLAHMRRNGSLTATDEALRARFVNLESRLLYLKFGPDALADCPFCVSEEPNTYLYYALPDLLAPHLLNLALLAMATSGLVSGGEGRRWRTVAVMSAAATAAADLYLVNAYDHQSNARALRPADLDMFFWAARRWRHAAFAAMDVVIAGLIWLSSTKRLFTEPPSPLERVEGVTRALASAKSRLSAVSIVKNTASRDSALRARSHAYWAHEVGVMNDVMEDREVVDGVKDALENRIKISAISQDAETYARNVVEAVMPGDEAQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU51</accession>
    <name>G4MU51_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15885</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715458.1">
        <property type="nucleotide sequence ID" value="XM_003715410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU51"/>
    <dbReference type="GeneID" id="12986680"/>
    <dbReference type="KEGG" id="mgr:MGG_15885"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15885"/>
    <dbReference type="eggNOG" id="ENOG502SFSH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078568_2_0_1"/>
    <dbReference type="InParanoid" id="G4MU51"/>
    <dbReference type="OMA" id="SDWGNRT"/>
    <dbReference type="OrthoDB" id="5336357at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="222" mass="24073" checksum="CF20B76A5CE9BBF1" modified="2011-12-14" version="1">MAILKRKRSESELSFSSQLSSPPRPGDAYFAFPVAPIGLSFSSRSSNPSHLNSRTVKRHRDNRPSENEVHQHTLELLYSARDVPSEHLQHAQQRAHIQPPASFASTQHQSPQQTPSARQTSLHSFWNLPRASSKAPPMMASFTPSTDLGSTSCEDCGSNLRSDESMMDVDDDGCGGAEACSCNACGKVVCFSCSVGNLGEHRRCLMCAGRGNGTSHLGWNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUE3</accession>
    <name>G4MUE3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_14807</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CMC family.</text>
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        <property type="protein sequence ID" value="EHA54830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003714589.1"/>
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    <dbReference type="STRING" id="242507.G4MUE3"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_14807"/>
    <dbReference type="eggNOG" id="ENOG502SBZE">
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    <dbReference type="HOGENOM" id="CLU_169286_3_0_1"/>
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        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977:SF1">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA54830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="80" mass="9465" checksum="42126EA0E30D0520" modified="2011-12-14" version="1">MHPHLHRVDNAGCEEIVQAFEECHARGFLWKSMGMCNDLKRSLTECLKAERAKHQLENRNNTNDKMRQVRAKWKEIDENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUG6</accession>
    <name>G4MUG6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thiol methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715465.1">
        <property type="nucleotide sequence ID" value="XM_003715417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUG6"/>
    <dbReference type="SMR" id="G4MUG6"/>
    <dbReference type="GeneID" id="2683133"/>
    <dbReference type="KEGG" id="mgr:MGG_07245"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07245"/>
    <dbReference type="eggNOG" id="ENOG502SXB2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_148138_1_0_1"/>
    <dbReference type="InParanoid" id="G4MUG6"/>
    <dbReference type="OMA" id="CLMRDME"/>
    <dbReference type="OrthoDB" id="4157208at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="8127" checksum="6B9D2DC9BAB7CFB1" modified="2011-12-14" version="1">MDASRSTQVPSTASTSARTSPATTQHVPAYQQPAASPVQSNQSTEPFLKDFTLIAEAARRAQMGIMVRDLESFGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUL8</accession>
    <name>G4MUL8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial import inner membrane translocase subunit TIM14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit tim14</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">Presequence translocated-associated motor subunit PAM18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_10159</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TIM14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713798.1">
        <property type="nucleotide sequence ID" value="XM_003713750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUL8"/>
    <dbReference type="SMR" id="G4MUL8"/>
    <dbReference type="FunCoup" id="G4MUL8">
        <property type="interactions" value="24"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUL8"/>
    <dbReference type="GeneID" id="2681786"/>
    <dbReference type="KEGG" id="mgr:MGG_10159"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10159"/>
    <dbReference type="eggNOG" id="KOG0723">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_13_3_1"/>
    <dbReference type="InParanoid" id="G4MUL8"/>
    <dbReference type="OMA" id="EPRMNKR"/>
    <dbReference type="OrthoDB" id="240298at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000001">
        <property type="entry name" value="Import inner membrane translocase subunit tim14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763:SF28">
        <property type="entry name" value="GEO10507P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="J" evidence="14">
        <location>
            <begin position="52"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00067223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00075483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA53991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="106" mass="11362" checksum="1C02073F741BFAEA" modified="2011-12-14" version="1">MASTVGLVAGAAVAAFLGRAGYVALRRSRGGVGAMGKAFYKGGFENKMNQKEASLILSLNERSITKDKVRKAHRTLMLLNHPDRGGSPYLATKINEAKELLEKQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV35</accession>
    <name>G4MV35_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2423 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713857.1">
        <property type="nucleotide sequence ID" value="XM_003713809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV35"/>
    <dbReference type="SMR" id="G4MV35"/>
    <dbReference type="GeneID" id="2679824"/>
    <dbReference type="KEGG" id="mgr:MGG_08838"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08838"/>
    <dbReference type="eggNOG" id="ENOG502SXGY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149452_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV35"/>
    <dbReference type="OMA" id="PIIREHK"/>
    <dbReference type="OrthoDB" id="4087970at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019434">
        <property type="entry name" value="DUF2423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28219">
        <property type="entry name" value="UPF0642 PROTEIN YBL028C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28219:SF1">
        <property type="entry name" value="UPF0642 PROTEIN YBL028C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10338">
        <property type="entry name" value="YBL028C_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2423" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="118" mass="12968" checksum="93D7E25AE02D42A8" modified="2011-12-14" version="1">MAKSLRASSRKANNQRLKRNVFGPVEAARNERLSAKLMEIATQPKEAKMEDAAPESDENAQAEDAAEDATATVMEVDSGSAPKAASSKKKRVEKKRGKKSKSAIVFSSYKDRITKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV83</accession>
    <name>G4MV83_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_15759</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714712.1">
        <property type="nucleotide sequence ID" value="XM_003714664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV83"/>
    <dbReference type="GeneID" id="12985385"/>
    <dbReference type="KEGG" id="mgr:MGG_15759"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15759"/>
    <dbReference type="eggNOG" id="ENOG502SD66">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042837_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV83"/>
    <dbReference type="OMA" id="CGYCERH"/>
    <dbReference type="OrthoDB" id="2534600at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052783">
        <property type="entry name" value="Metabolic/Drug-Res_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47655:SF2">
        <property type="entry name" value="QUINIC ACID UTILIZATION ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="335" mass="36067" checksum="EBA0888B35A66B47" modified="2011-12-14" version="1">MMSTVASIAATEKAAVRRPDVPDWEAAAAASDAVSEEKPANPRKRKKSSRACDFCHVNHQPCDNAKPRCGYCEKHGKQCLYLRPQKKRGPAQGYRNALHSMRESAAAWGVALSLIPELDTMVEAAIAQSDQDGQAISVSVKDPDQQDALIASWQQSRAFRAFFGDEAAVSATTGAAVSEKEEGSPKGNERPVAAQGTHSERSQPPAPLPGAEWQPAKKESPRPKHSSFLTSPPLHDGSLTGIGIQNIFDGMDHSLGLSFSVSDLVVKDAERSSDRFSQTLGSLGFAPGETLEDFVAMSSNPEPIHEGPSEEDPSLGSEMDQKAYYELLMGKSFFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVF3</accession>
    <name>G4MVF3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715586.1">
        <property type="nucleotide sequence ID" value="XM_003715538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVF3"/>
    <dbReference type="SMR" id="G4MVF3"/>
    <dbReference type="GeneID" id="2683065"/>
    <dbReference type="KEGG" id="mgr:MGG_07346"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07346"/>
    <dbReference type="eggNOG" id="ENOG502SNAB">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_010595_9_1_1"/>
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    <dbReference type="OMA" id="AMQWEEC"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="55"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="301" mass="32927" checksum="4E574CAE17F7FCD1" modified="2011-12-14" version="1">MTNNTMEEPRARGTDPLDSMEEIPERLDEQHETTTKILGFLIHPNIPVTSPTLKVADVGAGTGIWLLDVARSLPSTCQLTAYDKTPSGFPPSSAWPANVSFKIQDMYAPFPAAELGTYDLVAVRFVSSASTRADWARAVANLTTLLRPGGWLQWTDSCNFALYNSAPGTSRVACQEIYDGLDPFRPGLAGINGPVIGLMMRESCNVRRPDVFRDAGLVDVHEDVFSTDKLQDPGLGFRDKGTRNIMECFLGCLEELVTVEGSGWTKERIERLRGGAMGEIDAGVYHTLDQVCIIGRKPSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVJ8</accession>
    <name>G4MVJ8_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713914.1">
        <property type="nucleotide sequence ID" value="XM_003713866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVJ8"/>
    <dbReference type="GeneID" id="12987309"/>
    <dbReference type="KEGG" id="mgr:MGG_15602"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15602"/>
    <dbReference type="HOGENOM" id="CLU_2558716_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVJ8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465444" evidence="2">
        <location>
            <begin position="17"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="82" mass="8884" checksum="BF8D1999DB600292" modified="2011-12-14" version="1">MSPVAFAILLWPACQAQSGLDKGDGLEPERPNEERPAPSSCKERQSNVVIGTIVRLSADISVSEGNTSLVLTKAWMRYILLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVT7</accession>
    <name>G4MVT7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714810.1">
        <property type="nucleotide sequence ID" value="XM_003714762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVT7"/>
    <dbReference type="GeneID" id="12985415"/>
    <dbReference type="KEGG" id="mgr:MGG_15770"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15770"/>
    <dbReference type="HOGENOM" id="CLU_2250652_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVT7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="104" mass="11569" checksum="408893CF7ABE8E86" modified="2011-12-14" version="1">MAETLLYLTLYQQFWRPVLQPHLQLRLEAFVGPPAPVAGQAFCLLGNLSIRSRPACGKCEQPLWGQPIEHEPGQDGVSPPRPHLGTKVAPMSVSGNNNREKPWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW07</accession>
    <name>G4MW07_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
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    <proteinExistence type="predicted"/>
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            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="182"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="494"/>
            <end position="581"/>
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            <begin position="1"/>
            <end position="13"/>
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    </feature>
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            <begin position="59"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="693" mass="75303" checksum="A44CA150BC2472A6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
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        <name evidence="3" type="ORF">MGG_08957</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003713948.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MW36"/>
    <dbReference type="GeneID" id="2679942"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_08957"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465595" evidence="2">
        <location>
            <begin position="20"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="126" mass="13023" checksum="BD8259ECE9033541" modified="2011-12-14" version="1">MLAKHLIFATLPLLSLTAAVPIVETSLLGPLTNSAPLDSLAAQPPAQDPAATSEVQRRGAGDDARPPTQILKKIKNLGRKMTGQSRFPGTGRRVGSLADNEAQGKPAGQSSGGSARGQGESEQRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWA1</accession>
    <name>G4MWA1_PYRO7</name>
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        <recommendedName>
            <fullName evidence="5">Probable kinetochore protein NUF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_01848</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NUF2 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA55061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003714820.1"/>
    </dbReference>
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    <dbReference type="SMR" id="G4MWA1"/>
    <dbReference type="STRING" id="242507.G4MWA1"/>
    <dbReference type="GeneID" id="2679656"/>
    <dbReference type="KEGG" id="mgr:MGG_01848"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01848"/>
    <dbReference type="eggNOG" id="KOG4438">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_025461_2_1_1"/>
    <dbReference type="InParanoid" id="G4MWA1"/>
    <dbReference type="OMA" id="YLKMEAH"/>
    <dbReference type="OrthoDB" id="8194677at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051383">
        <property type="term" value="P:kinetochore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045132">
        <property type="term" value="P:meiotic chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.60">
        <property type="entry name" value="Ncd80 complex, Nuf2 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005549">
        <property type="entry name" value="Kinetochore_Nuf2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041112">
        <property type="entry name" value="Nuf2_DHR10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038275">
        <property type="entry name" value="Nuf2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21650">
        <property type="entry name" value="MEMBRALIN/KINETOCHORE PROTEIN NUF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03800">
        <property type="entry name" value="Nuf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18595">
        <property type="entry name" value="Nuf2_DHR10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="13" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Nuf2 N-terminal" evidence="16">
        <location>
            <begin position="30"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Nuf2 DHR10-like" evidence="17">
        <location>
            <begin position="285"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="172"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="340"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF18595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA55061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="467" mass="54391" checksum="33A872CEADA563F3" modified="2011-12-14" version="1">MAYNPRMSIIPPSQQQSRGKTNKREKEEQDLMILRDAEIVGCIRDLGFTKFDFSDLEKPNPLQVQMIFELFAEKTMNVTRETVDPAMRAAAEEVCGSADFGEALMPSDTRNLMGFYAAFRQLLVACGVPDFSFSDMYKPTHKRLVHLLSYLINFVRFRQGHAELFVEHFDRVQETKNRIDVLYSENQEMDARLDDMRRNRRAMESLAQEKTRRNEDLKRRLLELRRNQERVAARLEEAKSRKTELAQQLEQRTAEKLSLKQESSKLRPYTLQSPSALQASLADLSNTLNGERAHIDSLDRRARALQTSADSFTVVCADVASCIKLLDEIATELAKEDEESAKKSRQRDALAERGADVKEVERAESLLQRQLAKWNERTERLREQSSQRAQEAKEKMEELKAIHKKLNEERTEKGRDIETRRVRIEQTEKKMLDLKEQIEQEVHNAQDEYLKMEAHIKLYMTEMEQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWF0</accession>
    <name>G4MWF0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715717.1">
        <property type="nucleotide sequence ID" value="XM_003715669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWF0"/>
    <dbReference type="GeneID" id="12986756"/>
    <dbReference type="KEGG" id="mgr:MGG_15937"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15937"/>
    <dbReference type="HOGENOM" id="CLU_2961264_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWF0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="59" mass="6567" checksum="F94D30F002AD1A2E" modified="2011-12-14" version="1">MPWCSNTARGRRSRQLLVTKAVKHFHGSLRASIARVEQVPLPEVPRATRAISSASQQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWX3</accession>
    <name>G4MWX3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714072.1">
        <property type="nucleotide sequence ID" value="XM_003714024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWX3"/>
    <dbReference type="GeneID" id="12984580"/>
    <dbReference type="KEGG" id="mgr:MGG_15633"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15633"/>
    <dbReference type="HOGENOM" id="CLU_2746966_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWX3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465477" evidence="1">
        <location>
            <begin position="19"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="71" mass="7608" checksum="A08595294F939C0B" modified="2011-12-14" version="1">MKFNLIAISLALALTCYAKGPDKPKINKNCRNLTEQDAQVCRDPGRSVLCPANDFLGAFGGCCETDGCGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXA6</accession>
    <name>G4MXA6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715811.1">
        <property type="nucleotide sequence ID" value="XM_003715763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXA6"/>
    <dbReference type="GeneID" id="2678542"/>
    <dbReference type="KEGG" id="mgr:MGG_08275"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08275"/>
    <dbReference type="eggNOG" id="ENOG502SRTV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102245_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXA6"/>
    <dbReference type="OMA" id="GRHKYVK"/>
    <dbReference type="OrthoDB" id="2943660at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465738" evidence="1">
        <location>
            <begin position="19"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="202" mass="21252" checksum="0424D645F6B9B7FF" modified="2011-12-14" version="1">MVAIKPLILLGLAANAAAAGHGQQHANALHARQDYGKGKGGGSKCGKLNFVFTGLPWNHPAVQAAGFNPAMVEAAIKFDVQQIVQAGYNIKAILVGPEDPISDIAEEMDNVPGVKEWTGTGVGYGLRGPNSTVLTVRFTDVIQLFRDKEPNAPILFNHSPTTSLWAIQQKFPLPAGTNCSAEGKPGKNYGIAVHCSACPPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXH0</accession>
    <name>G4MXH0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_10968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713307.1">
        <property type="nucleotide sequence ID" value="XM_003713259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXH0"/>
    <dbReference type="GeneID" id="2677722"/>
    <dbReference type="KEGG" id="mgr:MGG_10968"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10968"/>
    <dbReference type="HOGENOM" id="CLU_2015723_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXH0"/>
    <dbReference type="OrthoDB" id="3920481at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="123" mass="13807" checksum="8FDE3365BC7F8CAA" modified="2011-12-14" version="1">MFRQTSPPVPAFSETVRVNHFDAQSCSDILGLCIHYLDPDDEVRTAAEPRIVHGPETFDPAYRQTTLALRRKVQLGYQTGVLGFNLFYYLKCAVATGHPTVERTEVATLQSGAELEKSKRHQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY55</accession>
    <name>G4MY55_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714193.1">
        <property type="nucleotide sequence ID" value="XM_003714145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY55"/>
    <dbReference type="SMR" id="G4MY55"/>
    <dbReference type="GeneID" id="2679442"/>
    <dbReference type="KEGG" id="mgr:MGG_01276"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01276"/>
    <dbReference type="HOGENOM" id="CLU_834385_0_0_1"/>
    <dbReference type="InParanoid" id="G4MY55"/>
    <dbReference type="OrthoDB" id="5241198at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="333" mass="36788" checksum="2FD0535C55C960A5" modified="2011-12-14" version="1">MRHQYLSPIVMDFISGNPQSSDGDDCENDQHRHRPHGLSIAQPSDLIMDSDLILQDVRSLQKRVSRLEDKLLEDNAQTSAAAAIGEIKTQISQILTSQKTLQSTNERILKKLDDLIQAEDVTLAVTNHISPKHDDQANAPKVAGELTEGQRKDNILSAWKNQSKIDRLAHKLNPSMPPGTLGLSGRYPSPYEETPEGVVLSQHRIDASKAKSKYAHNNLSGLNTESNIREYRKAIGPFSTAAERLTSLRENYLKIPNHSHDLTIRKKTDLTVLSPTEDASVREPACCICEKVTCSTPHHCLSGRNSSVDIPRVPGHLAGIRSACFDGENPMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYM5</accession>
    <name>G4MYM5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714257.1">
        <property type="nucleotide sequence ID" value="XM_003714209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYM5"/>
    <dbReference type="SMR" id="G4MYM5"/>
    <dbReference type="STRING" id="242507.G4MYM5"/>
    <dbReference type="GeneID" id="2679372"/>
    <dbReference type="KEGG" id="mgr:MGG_11230"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11230"/>
    <dbReference type="eggNOG" id="KOG2068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018455_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYM5"/>
    <dbReference type="OMA" id="DMQGLMN"/>
    <dbReference type="OrthoDB" id="1923159at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="600" mass="63174" checksum="E04A92508211BDBB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ77</accession>
    <name>G4MZ77_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_12309</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715157.1">
        <property type="nucleotide sequence ID" value="XM_003715109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ77"/>
    <dbReference type="STRING" id="242507.G4MZ77"/>
    <dbReference type="GeneID" id="5050910"/>
    <dbReference type="KEGG" id="mgr:MGG_12309"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12309"/>
    <dbReference type="eggNOG" id="KOG4344">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010106_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ77"/>
    <dbReference type="OMA" id="RTNQFEV"/>
    <dbReference type="OrthoDB" id="66546at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22572">
        <property type="entry name" value="GCP5_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059169">
        <property type="entry name" value="GCP5_N_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032797">
        <property type="entry name" value="Mod21_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF33">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14609">
        <property type="entry name" value="GCP5-Mod21_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-Tubulin ring complex non-core subunit mod21 N-terminal" evidence="8">
        <location>
            <begin position="67"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="9">
        <location>
            <begin position="235"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="546"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="156"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="824"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="839"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="865"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="928" mass="104902" checksum="9C0A277AB7F1B43D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZC3</accession>
    <name>G4MZC3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_04372</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713485.1">
        <property type="nucleotide sequence ID" value="XM_003713437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZC3"/>
    <dbReference type="SMR" id="G4MZC3"/>
    <dbReference type="GeneID" id="2677879"/>
    <dbReference type="KEGG" id="mgr:MGG_04372"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04372"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="InParanoid" id="G4MZC3"/>
    <dbReference type="OMA" id="AQSANWF"/>
    <dbReference type="OrthoDB" id="5399138at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
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        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
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    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
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    </dbReference>
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        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
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            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="339"/>
            <end position="357"/>
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    </feature>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="427"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="433"/>
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    </feature>
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        <location>
            <begin position="15"/>
            <end position="457"/>
        </location>
    </feature>
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        <location>
            <begin position="497"/>
            <end position="527"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA53678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="527" mass="56315" checksum="3453CF36F102AA14" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZY3</accession>
    <name>G4MZY3_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">Extracellular mutant protein 11 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_06150</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA52221.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003711980.1"/>
    </dbReference>
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    <dbReference type="SMR" id="G4MZY3"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_06150"/>
    <dbReference type="eggNOG" id="ENOG502STPQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="InParanoid" id="G4MZY3"/>
    <dbReference type="OMA" id="DWFLGRF"/>
    <dbReference type="OrthoDB" id="5346740at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070860">
        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001164">
        <property type="term" value="F:RNA polymerase I core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029178">
        <property type="entry name" value="Ecm11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053029">
        <property type="entry name" value="RNA_pol_I-specific_init_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244:SF3">
        <property type="entry name" value="EXTRACELLULAR MUTANT PROTEIN 11 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28244">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ECM11"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="474"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="613" mass="69025" checksum="86402A60E3B278F9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N067</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712909.1">
        <property type="nucleotide sequence ID" value="XM_003712861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N067"/>
    <dbReference type="GeneID" id="2683633"/>
    <dbReference type="KEGG" id="mgr:MGG_07706"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07706"/>
    <dbReference type="eggNOG" id="ENOG502SPRZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_760908_0_0_1"/>
    <dbReference type="InParanoid" id="G4N067"/>
    <dbReference type="OMA" id="ALHHTIN"/>
    <dbReference type="OrthoDB" id="5307331at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="364" mass="41892" checksum="2C560B3D50BEB689" modified="2011-12-14" version="1">METSQIATQMPMHLGHGNSAFSLRNNPISSAELARSLLPPKSAAPHGRPLHKLRRGRGRDGSRDDPNEFYWRLRGPPPSWAHGRSFFHYTCEGELNLLYKFGEEAFLDYLRQPELVLLIQRTPTLHNHRYPNHLLSPKCRFRQCRALHHTINRGEFRVALSEHPSLYGGMLDPFHCAGYVHLYCLESTLGVRKMVELHNQNRLVVHTHTLPMEEKDPMYIKGVPDEAGPYSRYIKWFSLAESWLNNSLHEPVEGDKTLNWYMTKGVVESQLPCQNRARQKRQLADFAKHMGNPEEKIRLRCANKAAKADKLRQEEAHGRTQAREGSQGGFRSRSRSPVCEKGRMPAHRQRDELLLMGQPGDDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0G0</accession>
    <name>G4N0G0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712101.1">
        <property type="nucleotide sequence ID" value="XM_003712053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0G0"/>
    <dbReference type="SMR" id="G4N0G0"/>
    <dbReference type="GeneID" id="12984277"/>
    <dbReference type="KEGG" id="mgr:MGG_15225"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15225"/>
    <dbReference type="HOGENOM" id="CLU_1768469_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0G0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="147" mass="15946" checksum="B8032FFC88F1E119" modified="2011-12-14" version="1">MPPAATAKRVFCIICTSEKGNAMADSGGKTAIGSRTHPNPEVLPDPDLDSDPDTHRFGSCDSDPDPDPDMTPIALAVRYMVACRMTCMLQGWLACTMEAIQEFRLEEDGHVLNASNLFILGPSINNFCLNTGKLSYKQPNLTLNSNV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-02-13" modified="2025-02-05" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N290</accession>
    <name>RED2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Short-chain dehydrogenase RED2</fullName>
            <ecNumber evidence="6">1.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Pyriculol/pyriculariol biosynthesis cluster protein RED2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RED2</name>
        <name type="ORF">MGG_12982</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2017" name="Microbiology" volume="163" first="541" last="553">
            <title>Unravelling the biosynthesis of pyriculol in the rice blast fungus Magnaporthe oryzae.</title>
            <authorList>
                <person name="Jacob S."/>
                <person name="Groetsch T."/>
                <person name="Foster A.J."/>
                <person name="Schueffler A."/>
                <person name="Rieger P.H."/>
                <person name="Sandjo L.P."/>
                <person name="Liermann J.C."/>
                <person name="Opatz T."/>
                <person name="Thines E."/>
            </authorList>
            <dbReference type="PubMed" id="27902426"/>
            <dbReference type="DOI" id="10.1099/mic.0.000396"/>
        </citation>
        <scope>IDENTIFICATION</scope>
        <scope>INDUCTION</scope>
        <scope>FUNCTION</scope>
        <scope>PATHWAY</scope>
    </reference>
    <comment type="function">
        <text evidence="3 6">Short-chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of pyriculol and pyriculariol, two heptaketides that induce lesion formation upon application on rice leaves but are dispensable for pathogenicity (PubMed:27902426). The highly reducing polyketide synthase synthesizes the heptaketide backbone of pyriculol and pyriculariol (PubMed:27902426). Pyriculol and pyriculariol contain several hydroxyl moieties and double bonds, so it can be assumed that several reduction steps occur during biosynthesis. These reactions could be executed by PKS19 itself or partly by the tailoring enzymes OXR1, OXR2, RED1, RED2 or RED3, identified within the cluster (Probable). The FAD-linked oxidoreductase OXR1 is the only tailoring enzyme for which the function has been determined yet, and is involved in the oxidation of dihydropyriculol and dihydropyriculariol into pyriculol and pyriculariol, respectively (PubMed:27902426).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Polyketide biosynthesis.</text>
    </comment>
    <comment type="induction">
        <text evidence="3">Expression is increased in rice-extract medium (REM) and is correlated with the production of pyriculol.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712309.1">
        <property type="nucleotide sequence ID" value="XM_003712261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N290"/>
    <dbReference type="SMR" id="G4N290"/>
    <dbReference type="STRING" id="242507.G4N290"/>
    <dbReference type="EnsemblFungi" id="MGG_12982T0">
        <property type="protein sequence ID" value="MGG_12982T0"/>
        <property type="gene ID" value="MGG_12982"/>
    </dbReference>
    <dbReference type="GeneID" id="2677059"/>
    <dbReference type="KEGG" id="mgr:MGG_12982"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12982"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_0_1"/>
    <dbReference type="InParanoid" id="G4N290"/>
    <dbReference type="OMA" id="PMINSNE"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24321:SF12">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000446269" description="Short-chain dehydrogenase RED2">
        <location>
            <begin position="1"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Lowers pKa of active site Tyr" evidence="2">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="L0E2Z4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="O93868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="27902426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="4">
        <source>
            <dbReference type="PubMed" id="27902426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <evidence type="ECO:0000305" key="6">
        <source>
            <dbReference type="PubMed" id="27902426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="278" mass="28647" checksum="66A4891025C7ADA2" modified="2011-12-14" version="1">MNTTGSAFVIGASGIGRACALAFARRGVSGLVVADVDLQAAESLAAECRAEAGSAGTADALGCAEATRVDVADERSVELAVSFARRVLGRVDYCVNSAGIGVKLANEIADASPVEFEAMFQVNVKGTFLVTRAVSALMKTQDPVPVLRDSPGRGTTRGCIVILGSAAAFAATPKMVQYTTAKHAVLGLTKSAALDNAAHGIRVNSVCPSWVDTPMVRRALQDVPELEQTIRTSVPMGRIALAEEVADAVMFLCSPGASYATGCNMILDGGTTLTTHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2G7</accession>
    <name>G4N2G7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713179.1">
        <property type="nucleotide sequence ID" value="XM_003713131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2G7"/>
    <dbReference type="GeneID" id="2683859"/>
    <dbReference type="KEGG" id="mgr:MGG_13916"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13916"/>
    <dbReference type="eggNOG" id="ENOG502T592">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_685257_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2G7"/>
    <dbReference type="OrthoDB" id="5232600at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="402" mass="45293" checksum="63D6CE9BE22A9EDE" modified="2011-12-14" version="1">MENPQTDDPWRPGWDPRRLATLTRPDPRYYRYVPDLSGYFVVAHYQTPDWRPGEGDPSSIRWLLEEAPELIVDGRLRVDSEDLDGQTRSCLAGVGGSGAEARVMAQQKSPSSAPPVVRPFGGRPGWSGGESTYDQSCGVARDYPQRGRQDWQTGESKSQALQRHQNPQNHGFQGQQSQFELSMEQGNSKRNGPIHHQQQRPTPQRHSSNESSEDSQRSWIWPENSDIALPGQQMDPRHMRISQDVLAKIHRYPMGHPQSPWGWPETSDGSGVTGLTESESIGMREARRRHNAEIEKRAPHPQRFIRPSSPGTSNWGPRRDSRDGSTWSKNSSSSFRVQMPQWPSAQQYSGSRDSPSYLHGTQRISDESLDYTDSSGSGETLDQRRGDYVYGGFEERGNGRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2P2</accession>
    <name>G4N2P2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CipC-like antibiotic response protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712354.1">
        <property type="nucleotide sequence ID" value="XM_003712306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2P2"/>
    <dbReference type="SMR" id="G4N2P2"/>
    <dbReference type="GeneID" id="2675315"/>
    <dbReference type="KEGG" id="mgr:MGG_04873"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04873"/>
    <dbReference type="eggNOG" id="ENOG502S76S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_143683_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2P2"/>
    <dbReference type="OMA" id="MAWGWEQ"/>
    <dbReference type="OrthoDB" id="9895617at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="14148" checksum="1AFCF5E2863DB1DC" modified="2011-12-14" version="1">MFGFDEAKEHRDEFYNGTPHESKLSHELLASAASFEAMHLWEKKQRESGQPVNHGLAKEMLAAAAGFEVDKLVETKGLDMIDREKAKHHAKQQAERMYDEQYGQYAEYNPEQQRPHRHMQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2T1</accession>
    <name>G4N2T1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Muniscin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712393.1">
        <property type="nucleotide sequence ID" value="XM_003712345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2T1"/>
    <dbReference type="SMR" id="G4N2T1"/>
    <dbReference type="FunCoup" id="G4N2T1">
        <property type="interactions" value="136"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N2T1"/>
    <dbReference type="GeneID" id="2675325"/>
    <dbReference type="KEGG" id="mgr:MGG_04906"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04906"/>
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            <end position="773"/>
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        </location>
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            <end position="755"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="10"/>
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        <location>
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            <end position="141"/>
        </location>
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            <end position="172"/>
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    </feature>
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            <end position="234"/>
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    </feature>
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            <end position="261"/>
        </location>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA52586.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N382</accession>
    <name>G4N382_PYRO7</name>
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            <fullName evidence="2">Delta(24)-sterol reductase</fullName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Single-pass membrane protein</topology>
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    <dbReference type="Proteomes" id="UP000009058">
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    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Diminuto-like"/>
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        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801">
        <property type="entry name" value="24-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801:SF0">
        <property type="entry name" value="DELTA(24)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3B3</accession>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003711598.1">
        <property type="nucleotide sequence ID" value="XM_003711550.1"/>
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    <dbReference type="AlphaFoldDB" id="G4N3B3"/>
    <dbReference type="GeneID" id="2683582"/>
    <dbReference type="KEGG" id="mgr:MGG_07662"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07662"/>
    <dbReference type="eggNOG" id="ENOG502T3GI">
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    <dbReference type="HOGENOM" id="CLU_424563_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3B3"/>
    <dbReference type="OrthoDB" id="5198810at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
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    <dbReference type="SUPFAM" id="SSF101447">
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        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="645" mass="73588" checksum="527A857D90DEBAB7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3C3</accession>
    <name>G4N3C3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711608.1">
        <property type="nucleotide sequence ID" value="XM_003711560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3C3"/>
    <dbReference type="GeneID" id="2683589"/>
    <dbReference type="KEGG" id="mgr:MGG_07669"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07669"/>
    <dbReference type="HOGENOM" id="CLU_2097337_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3C3"/>
    <dbReference type="OrthoDB" id="5227643at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="116" mass="12768" checksum="90E65E9396E466A0" modified="2011-12-14" version="1">MAVAKDALAIVIVLGVTIFASGVAIYYYQSRRHQKRATALKNSHRSYDVENQAMISLKREPQATMWRCKSDAGPRAKQPSANRAGLPRSQSAGATVGLARPALAHLPRWTRPARRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3L9</accession>
    <name>G4N3L9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="4 12">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">5-proFAR isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 12">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_04998</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="4 12"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712501.1">
        <property type="nucleotide sequence ID" value="XM_003712453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3L9"/>
    <dbReference type="SMR" id="G4N3L9"/>
    <dbReference type="FunCoup" id="G4N3L9">
        <property type="interactions" value="207"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N3L9"/>
    <dbReference type="GeneID" id="2675684"/>
    <dbReference type="KEGG" id="mgr:MGG_04998"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04998"/>
    <dbReference type="eggNOG" id="KOG3055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065050_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3L9"/>
    <dbReference type="OMA" id="IEWNKTH"/>
    <dbReference type="OrthoDB" id="446074at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04723">
        <property type="entry name" value="HisA_HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000110">
        <property type="entry name" value="1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011858">
        <property type="entry name" value="His6/HISN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02129">
        <property type="entry name" value="hisA_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090:SF2">
        <property type="entry name" value="1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8 12 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA52694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="261" mass="28334" checksum="FBE52C74545E86DB" modified="2011-12-14" version="1">MTRFRPCIDLHAGQVKQIVGGTLDSTTSELRTNFVSPHPPAHFARLYRDANLVGAHVIMLGPGNDVAAKESLAAWPGGLQVGGGITDKNAAEWIANGADKAIITSFLFPEGRFSQSRLDAVLAALGNDKSKLVIDLSCRRRDTGPEPKWVVAMNKWQTLTDMEVNQDSIKKLEPYCSEFLIHAADNEGLQGGIDEDLVRNLAEWCSIPVTYAGGGRNLDDLEAVKRLSNGKVDLTIGSALDCFGGSGVKLDDCIEWNKRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3Y3</accession>
    <name>G4N3Y3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AVR-Pik-like HMA interaction domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_13283</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711712.1">
        <property type="nucleotide sequence ID" value="XM_003711664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3Y3"/>
    <dbReference type="STRING" id="242507.G4N3Y3"/>
    <dbReference type="GeneID" id="2684090"/>
    <dbReference type="KEGG" id="mgr:MGG_13283"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13283"/>
    <dbReference type="HOGENOM" id="CLU_966676_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3Y3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055026">
        <property type="entry name" value="AVR-Pik_HID"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22383">
        <property type="entry name" value="AVR-Pik_HID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465962" description="AVR-Pik-like HMA interaction domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="AVR-Pik-like HMA interaction" evidence="3">
        <location>
            <begin position="233"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="288" mass="29559" checksum="45B48E853751CF1A" modified="2011-12-14" version="1">MRITTLTALAIALLGNSATVGATDGGPVIQRRMYNGGYGGGYGNCPGGSCPPRGGYGGGYGGGYAGYGGGYGGGYGNCPGGSCPPRGGYGGYSASGYGGGGGYDDGGYGHSPSYGGGGGGYDDGSYEHSPSYAGGGGGYDDGSHGHSTSYGGGGGGGGHRTPEVESTSERRTESSSSRWPPGTRSEDYPDPPISPYLNQRVRECVWFWFEYAQPTTKSSGGWFRSGKKKPTGPKQWIMREAGEMYSGHTIRMNVGLKGEIPVTSDEGCDMSGDFPTGWTVVGRRRKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N469</accession>
    <name>G4N469_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CSN8/PSMD8/EIF3K domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712596.1">
        <property type="nucleotide sequence ID" value="XM_003712548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N469"/>
    <dbReference type="SMR" id="G4N469"/>
    <dbReference type="STRING" id="242507.G4N469"/>
    <dbReference type="GeneID" id="12985110"/>
    <dbReference type="KEGG" id="mgr:MGG_16861"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16861"/>
    <dbReference type="eggNOG" id="ENOG502RXZN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055649_0_0_1"/>
    <dbReference type="InParanoid" id="G4N469"/>
    <dbReference type="OMA" id="WTWEKLV"/>
    <dbReference type="OrthoDB" id="2100128at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39398:SF1">
        <property type="entry name" value="CSN8_PSMD8_EIF3K DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39398">
        <property type="entry name" value="YALI0F14311P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="34143" checksum="88C73D6B047DED1A" modified="2011-12-14" version="1">MPPGRGAAGAWGRLKPVELDALEAMGLPSKGETRLLDPRTQNQYYTEIVKRYLTFCSDAGDRDSLLAQFASMSIGTGKKPSSQHSDTAPTAATKQVGPRLPPPDGAAVAAGGPKSKDLVVVMMALRKLREAIVATKRADDFAVQVYLFNIRLAILVKTPESYHPAIQHLLRRIHPVAQPLTSVELQEVVGYLVLDAACRRGDLSEAHVARLQYGLRDPKVDAVLDALAHDNYAAFARLRGQVDGHKAKLMEFAAPTMRRHALSCLGRSYLSVDVGFLEKSAGRAWAELQREDGVGWERDGQRVVIRKMKAKT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2023-06-28" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4J5</accession>
    <name>LIDS_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">7,8-linoleate diol synthase</fullName>
            <shortName evidence="8">LDS</shortName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">Linoleate 8R-lipoxygenase</fullName>
                <ecNumber evidence="6 7">1.13.11.60</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">9,12-octadecadienoate 8-hydroperoxide 8R-isomerase</fullName>
                <ecNumber evidence="6 7">5.4.4.6</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name type="ORF">MGG_13239</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2010" name="J. Biol. Chem." volume="285" first="5308" last="5316">
            <title>Gene deletion of 7,8-linoleate diol synthase of the rice blast fungus: studies on pathogenicity, stereochemistry, and oxygenation mechanisms.</title>
            <authorList>
                <person name="Jerneren F."/>
                <person name="Sesma A."/>
                <person name="Franceschetti M."/>
                <person name="Hamberg M."/>
                <person name="Oliw E.H."/>
            </authorList>
            <dbReference type="PubMed" id="20023302"/>
            <dbReference type="DOI" id="10.1074/jbc.m109.062810"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <scope>CATALYTIC ACTIVITY</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2014" name="J. Lipid Res." volume="55" first="2113" last="2123">
            <title>Epoxy alcohol synthase of the rice blast fungus represents a novel subfamily of dioxygenase-cytochrome P450 fusion enzymes.</title>
            <authorList>
                <person name="Hoffmann I."/>
                <person name="Jerneren F."/>
                <person name="Oliw E.H."/>
            </authorList>
            <dbReference type="PubMed" id="25121983"/>
            <dbReference type="DOI" id="10.1194/jlr.m051755"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DOMAIN</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>MUTAGENESIS OF SER-350; SER-753; ASN-946; SER-975; THR-998 AND THR-1098</scope>
    </reference>
    <comment type="function">
        <text evidence="6 7">7,8-linoleate diol synthase is a bifunctional enzyme that converts linoleic acid (18:2n-6) into 8-hydroperoxy-8(E),12(Z)-octadecadienoic acid (8-HPODE) and then catalyzes the isomerization of the resulting hydroperoxide to 7,8-dihydroxy-9(Z),12(Z)-octadecadienoic acid (7,8-DiHODE).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(9Z,12Z)-octadecadienoate + O2 = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate</text>
            <dbReference type="Rhea" id="RHEA:25395"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30245"/>
            <dbReference type="ChEBI" id="CHEBI:58659"/>
            <dbReference type="EC" id="1.13.11.60"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6 7">
            <dbReference type="Rhea" id="RHEA:25396"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate</text>
            <dbReference type="Rhea" id="RHEA:25399"/>
            <dbReference type="ChEBI" id="CHEBI:57468"/>
            <dbReference type="ChEBI" id="CHEBI:58659"/>
            <dbReference type="EC" id="5.4.4.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6 7">
            <dbReference type="Rhea" id="RHEA:25400"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="6">Impairs the production of 8-hydroperoxy-8(E),12(Z)-octadecadienoic acid (8-HPODE) and 7,8-dihydroxy-9(Z),12(Z)-octadecadienoic acid (7,8-DiHODE) (PubMed:20023302). Does not affect appressoria and conidia formation, nor the infection of rice leaves and roots (PubMed:20023302).</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the peroxidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the C-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003711769.1"/>
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    <dbReference type="AlphaFoldDB" id="G4N4J5"/>
    <dbReference type="SMR" id="G4N4J5"/>
    <dbReference type="STRING" id="242507.G4N4J5"/>
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        <property type="protein sequence ID" value="MGG_13239T0"/>
        <property type="gene ID" value="MGG_13239"/>
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    <dbReference type="GeneID" id="5049104"/>
    <dbReference type="KEGG" id="mgr:MGG_13239"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13239"/>
    <dbReference type="eggNOG" id="KOG2408">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002329_1_0_1"/>
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    <dbReference type="OMA" id="KIQWDGD"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052879">
        <property type="term" value="F:9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052878">
        <property type="term" value="F:linoleate 8R-lipoxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
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    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
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    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
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    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
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    </dbReference>
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        <property type="entry name" value="CYP_LDS-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09817">
        <property type="entry name" value="linoleate_diol_synthase_like"/>
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    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Haem_peroxidase_animal"/>
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        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
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    <dbReference type="InterPro" id="IPR050783">
        <property type="entry name" value="Oxylipin_biosynth_metab"/>
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    <dbReference type="InterPro" id="IPR034812">
        <property type="entry name" value="Ppo-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903">
        <property type="entry name" value="PROSTAGLANDIN G/H SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11903:SF37">
        <property type="entry name" value="PSI-PRODUCING OXYGENASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0106">Calcium</keyword>
    <keyword id="KW-0223">Dioxygenase</keyword>
    <keyword id="KW-0349">Heme</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000458149" description="7,8-linoleate diol synthase">
        <location>
            <begin position="1"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Fatty acid alpha-dioxygenase" evidence="9">
        <location>
            <begin position="114"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Epoxy alcohol synthase" evidence="9">
        <location>
            <begin position="675"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="873"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="881"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="1089"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="mutagenesis site" description="Does not affect the enzymatic oxidation of linoleic acid (18:2n-6)." evidence="7">
        <original>S</original>
        <variation>D</variation>
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Does not affect the enzymatic oxidation of linoleic acid (18:2n-6)." evidence="7">
        <original>S</original>
        <variation>E</variation>
        <location>
            <position position="753"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Forms only small amounts of the 7,8-diol." evidence="7">
        <original>N</original>
        <variation>V</variation>
        <location>
            <position position="946"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Does not affect the enzymatic oxidation of linoleic acid (18:2n-6)." evidence="7">
        <original>S</original>
        <variation>D</variation>
        <location>
            <position position="975"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Does not affect the enzymatic oxidation of linoleic acid (18:2n-6)." evidence="7">
        <original>T</original>
        <variation>E</variation>
        <location>
            <position position="998"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Does not affect the enzymatic oxidation of linoleic acid (18:2n-6)." evidence="7">
        <original>T</original>
        <variation>D</variation>
        <location>
            <position position="1098"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="P04798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="Q9UUS2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3"/>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="6">
        <source>
            <dbReference type="PubMed" id="20023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="7">
        <source>
            <dbReference type="PubMed" id="25121983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="8">
        <source>
            <dbReference type="PubMed" id="20023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="9">
        <source>
            <dbReference type="PubMed" id="25121983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="10"/>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA52010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1171" mass="129879" checksum="0CB47BAF1CE97EAF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4J7</accession>
    <name>G4N4J7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Erythromycin biosynthesis protein CIII-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711819.1">
        <property type="nucleotide sequence ID" value="XM_003711771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4J7"/>
    <dbReference type="SMR" id="G4N4J7"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="GeneID" id="12984223"/>
    <dbReference type="KEGG" id="mgr:MGG_16729"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16729"/>
    <dbReference type="eggNOG" id="ENOG502TE0J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_4_1_1"/>
    <dbReference type="InParanoid" id="G4N4J7"/>
    <dbReference type="OMA" id="GVESWFY"/>
    <dbReference type="OrthoDB" id="1363at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015:SF22">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="1">
        <location>
            <begin position="347"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="474" mass="51797" checksum="6BAB0E47CD7E1100" modified="2011-12-14" version="1">MTSKRDPYILILSHALTGHITPMLSVAGALLSRGWDVGFLGPTTHRAKIGSAGCEFFSLRGKADIDDSLGTPAALGDGVDGHLPPHMRRILSDTRVQCYDTIPDQWDCIKEVLSALHARDADRQVLVICEAFVHGILPLKYGAALPPGIPEPKTICVSVTPPMIRTRLQPPFYSALPYDPSPAGEARAAELWEEWGGGVGAEMESYLDVKVMRAGGTRRTKQLFLEGVNYTCHDSILQFGLESFEYPRDDWPAGRFHFIGLPPPKGRRGVSEAEVRDVPWWEGFVANAELPGRDPTRSKVVIVTQGTVEADATELIVPTLQAATRLAQEESLKLFLVVILGVRNASLPPSVCTVPPNVGVVDYLRYGAVLPYADVWVHNGGYGAVSQGIAEGVPMIVAGEGQDKAENARRVAWSGIGLDLKTARPTAEQVANSILEVLRDGSQYRDKVNDMQSQLKLYNFEETVDREVRKQIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4W1</accession>
    <name>G4N4W1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711880.1">
        <property type="nucleotide sequence ID" value="XM_003711832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4W1"/>
    <dbReference type="GeneID" id="2683944"/>
    <dbReference type="KEGG" id="mgr:MGG_06031"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06031"/>
    <dbReference type="HOGENOM" id="CLU_549894_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4W1"/>
    <dbReference type="OrthoDB" id="5224765at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="496" mass="54923" checksum="3713B10B01D4187F" modified="2011-12-14" version="1">MPPAPRSEAPHPHIQLRDNVPPAKPPAICAAHYVIGDSSDDVSTTSVEEPKDNAASRVDEPTTADNIISGRHVPEIQEIISPTLDLYKPFPKVEPPMRNMELMTPRKLQRSSLHGSLFEGLDKVGLGANAFSRKPLFEASPRSMDCISHPDSRSAAESAATIQKSDGKVVIMNPSESSLKCETQSRSDSRRLRGGGGLKELKLKLENSRLGRYYRHKMRRCTSHDPDICDDQKRRCTTRKERIHWYQPWRRVKWFKGAQYRKGRRATHGTPRPQSSGGRVFGYAIMHSSEESRGGQTMPQRQGSRFRTEFDENTGLMINQEPNERVLHRANFRTAMGVHLEQIIEVASEFERSIQEEAVATTTTTTEAAPHAQKPSHHLARGSEILNPENTRVDKPLVSKVSHEQPDSEAENSLVPGLTSADTLVSGLQGPTTPSRSASRAATVASTGIDSLTNEDNFDDDADFLLSTDSINSAMIPVSEPIREHNHVVLGSSLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N529</accession>
    <name>G4N529_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712747.1">
        <property type="nucleotide sequence ID" value="XM_003712699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N529"/>
    <dbReference type="SMR" id="G4N529"/>
    <dbReference type="STRING" id="242507.G4N529"/>
    <dbReference type="GeneID" id="2675676"/>
    <dbReference type="KEGG" id="mgr:MGG_05202"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05202"/>
    <dbReference type="eggNOG" id="ENOG502T4HG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_631731_0_0_1"/>
    <dbReference type="InParanoid" id="G4N529"/>
    <dbReference type="OMA" id="ETHDANI"/>
    <dbReference type="OrthoDB" id="4925544at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="406" mass="45274" checksum="E4E1F732F31BBC45" modified="2011-12-14" version="1">MSEPSRGSASVPTLRFPRPQGNQRLANWISSSSPDIMAQAFFVDEDGAVDSYELINTDGETESQDGLTTGSTASSLDLLARPSDDDSLSVVDHIYECETHDANIHTDEHQDYTEEVEQATTHEDDGYQSEVDLVTPAHTCEVDKDIDVLLTKPSKVIEPQKVVKFQTDGKYTIVDHIRRSAQNPDFLHKAWIVLAVLASLIAVTTFNTMGTALIRSPIKACEQPIPGQIQHALITTVSVKPPTTVTTTVTTTSTVLPPAFSDIAKKLTGSAEGVAKSVEETYLPALFAYATKVRGEVADWRKTHGLTGEALIKARNELKDRFTPYIRVAEDSANDLKLNFLKAQIKSRLVWLQIRGEVAEYQRYQTQARDYLKAKRHQMLTLRALRDRKSTSTSRWGRSHLRHIFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N537</accession>
    <name>G4N537_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial import receptor subunit tom-22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_05210</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712755.1">
        <property type="nucleotide sequence ID" value="XM_003712707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N537"/>
    <dbReference type="FunCoup" id="G4N537">
        <property type="interactions" value="248"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N537"/>
    <dbReference type="GeneID" id="2675585"/>
    <dbReference type="KEGG" id="mgr:MGG_05210"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05210"/>
    <dbReference type="eggNOG" id="KOG4111">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094333_1_0_1"/>
    <dbReference type="InParanoid" id="G4N537"/>
    <dbReference type="OMA" id="LVWIVTT"/>
    <dbReference type="OrthoDB" id="10016939at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22884">
        <property type="entry name" value="TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005683">
        <property type="entry name" value="Tom22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04281">
        <property type="entry name" value="Tom22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA52948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="165" mass="17740" checksum="51BFDD5D21469A65" modified="2011-12-14" version="1">MVQLTEVVDEEFLKTQPGHDEEDDDFTDTDSEISTDSDYDVSGETLSDRIYALRDIVPPTTRGWIHGKWMGATNIFRTTAAFLGRSAWHISVSAMLFGIPFALLWSEEQGMIAMEQEQRMREQGGELLTAGAAGGAPGGGDINSLDQLESALGGGVGSVSAKPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N549</accession>
    <name>G4N549_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_15140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712767.1">
        <property type="nucleotide sequence ID" value="XM_003712719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N549"/>
    <dbReference type="SMR" id="G4N549"/>
    <dbReference type="STRING" id="242507.G4N549"/>
    <dbReference type="GeneID" id="12985185"/>
    <dbReference type="KEGG" id="mgr:MGG_15140"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15140"/>
    <dbReference type="eggNOG" id="KOG1716">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012050_0_0_1"/>
    <dbReference type="InParanoid" id="G4N549"/>
    <dbReference type="OMA" id="QAKSRWI"/>
    <dbReference type="OrthoDB" id="426001at2759"/>
    <dbReference type="PHI-base" id="PHI:7273"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14521">
        <property type="entry name" value="DSP_fungal_SDP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="331"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="438"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="519"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="623"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="814"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="590"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="630"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="645"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="715"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="838"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="874" mass="94328" checksum="9C6DDFDE29E3004B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5G5</accession>
    <name>G4N5G5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_09070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA51365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711172.1">
        <property type="nucleotide sequence ID" value="XM_003711124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5G5"/>
    <dbReference type="SMR" id="G4N5G5"/>
    <dbReference type="GeneID" id="2680021"/>
    <dbReference type="KEGG" id="mgr:MGG_09070"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09070"/>
    <dbReference type="eggNOG" id="ENOG502SMK9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_4_1"/>
    <dbReference type="InParanoid" id="G4N5G5"/>
    <dbReference type="OMA" id="MRIPLHI"/>
    <dbReference type="OrthoDB" id="3648173at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="36"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="264"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA51365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="371" mass="39900" checksum="DEEEA84D3F076132" modified="2011-12-14" version="1">MADSINHSLDHESRVGNIYASVIISLTAVTVVVLGRIYTRLFILKTFGLDDWAAAISLVFTLACGILVGFNAKYGCGRHIWTVGPAELQQFFIASFLLQYYRVLATTRAMKQTYLAFLVIVVSACIAFTFVAIFACTPISDFWSFDSKKNCLPNFTIYYAQAGANIGTDIIIFALPLPALWKLRINGPQKLVLLGIFSLGFFATVISILRLTFLDDSPDITWSNAISSSWSTAEISIGLMCASLPSLRPLVGKVLPRLASTFGKSASPSKGAYGASGNRYGAKASQGGSRVPTFSTTATSSSRPQKTLSLYPDLEGSASVERLNSDDQATKFPGSPGTFLDDSSDRGGYPMTEFGTRTKVTAGDVPGHPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5J4</accession>
    <name>G4N5J4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711994.1">
        <property type="nucleotide sequence ID" value="XM_003711946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5J4"/>
    <dbReference type="GeneID" id="12984260"/>
    <dbReference type="KEGG" id="mgr:MGG_16760"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16760"/>
    <dbReference type="HOGENOM" id="CLU_1938576_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5J4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="130" mass="14542" checksum="0A494017FCFF2A6D" modified="2011-12-14" version="1">MRQPNPWAPLLDDLILTTLRVGFSPPATKAGKDKNEVHGLSLAFGYKLGAHLYVSWEVKIRNRSSSMVKAPLHHPTSRELISPSFQSHNPLSSTPVQVPRTTRTDDYPWLDTTSIVTPTISGRAPCNPWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5S0</accession>
    <name>G4N5S0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712867.1">
        <property type="nucleotide sequence ID" value="XM_003712819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5S0"/>
    <dbReference type="GeneID" id="12985797"/>
    <dbReference type="KEGG" id="mgr:MGG_15141"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15141"/>
    <dbReference type="HOGENOM" id="CLU_1713633_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5S0"/>
    <dbReference type="OrthoDB" id="10433326at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="153" mass="17254" checksum="6FB2A2107BC9A57B" modified="2011-12-14" version="1">MHVALICHCHLADEVGVCGISVYTKTTWHNNVAVQNADGTRKRNYKRPAHYADGWYGTIWCAKMTRVKVPRLDLKHSTLGWKRSVHRVWQLFTAKPSEHTHTTSMSLWWPRSSQLDEAPAANFSFCSDTGEKSPQPTPGSEPTTVPAQRPAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5Z6</accession>
    <name>G4N5Z6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716891.1">
        <property type="nucleotide sequence ID" value="XM_003716843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5Z6"/>
    <dbReference type="SMR" id="G4N5Z6"/>
    <dbReference type="GeneID" id="12985476"/>
    <dbReference type="KEGG" id="mgr:MGG_17147"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17147"/>
    <dbReference type="HOGENOM" id="CLU_2961269_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5Z6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="59" mass="6713" checksum="611FBE56A6576291" modified="2011-12-14" version="1">MVGKLGRVDDNFEDWMDPCMEARTRRLLPSIKEVSAHCKISATAIRSKVGRLGPLLTWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N696</accession>
    <name>G4N696_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12 13">Endo-1,4-beta-xylanase</fullName>
            <ecNumber evidence="4 12 13">3.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_17154</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-xylosidic linkages in xylans.</text>
            <dbReference type="EC" id="3.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12 13">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12 13">Belongs to the glycosyl hydrolase 11 (cellulase G) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.8" evidence="4 12 13"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716937.1">
        <property type="nucleotide sequence ID" value="XM_003716889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N696"/>
    <dbReference type="SMR" id="G4N696"/>
    <dbReference type="STRING" id="242507.G4N696"/>
    <dbReference type="CAZy" id="GH11">
        <property type="family name" value="Glycoside Hydrolase Family 11"/>
    </dbReference>
    <dbReference type="GeneID" id="12985489"/>
    <dbReference type="KEGG" id="mgr:MGG_17154"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17154"/>
    <dbReference type="eggNOG" id="ENOG502RXA7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052631_0_0_1"/>
    <dbReference type="InParanoid" id="G4N696"/>
    <dbReference type="OMA" id="NWANDFA"/>
    <dbReference type="OrthoDB" id="2115822at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031176">
        <property type="term" value="F:endo-1,4-beta-xylanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013319">
        <property type="entry name" value="GH11/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033123">
        <property type="entry name" value="GH11_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001137">
        <property type="entry name" value="Glyco_hydro_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46828:SF2">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00457">
        <property type="entry name" value="Glyco_hydro_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00911">
        <property type="entry name" value="GLHYDRLASE11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51761">
        <property type="entry name" value="GH11_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12 13" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="5 12 13" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466176" description="Endo-1,4-beta-xylanase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="GH11" evidence="15">
        <location>
            <begin position="34"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="12">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA50618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="256" mass="28053" checksum="87FD6F6BB70DF92B" modified="2011-12-14" version="1">MLPSCILALVLPLASVLAADFTGPTLPPHLSSAALEELGKRQTQQWRTQNWGNEFSNYTWSPGPNGRFAVDWRQPNGGNFVVGRGYSLNNNNRIFNYSGTFTVNDRAYMCLYAWTLNPLTEWYVIENMGVHNPADNRNATCHGRIQSDGGTYEVWSKWRINAPSIIGDADFQQYWSIRTRRHVGGTINTTAHLAAFRRAGLPLGAQQPVFLAVEGQVGSGAATLTAGVAPTTTVPESATPTARTELVPSRACTRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6E9</accession>
    <name>G4N6E9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA49819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003716090.1"/>
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    <dbReference type="KEGG" id="mgr:MGG_03741"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03741"/>
    <dbReference type="eggNOG" id="ENOG502QPI0">
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    <dbReference type="OMA" id="MWRGSIM"/>
    <dbReference type="OrthoDB" id="9999821at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <dbReference type="GO" id="GO:0005741">
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        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
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        <property type="term" value="C:mitochondrion"/>
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        <property type="term" value="C:plasma membrane"/>
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    </dbReference>
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        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR038607">
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    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
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    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF1">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="2"/>
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    <proteinExistence type="predicted"/>
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            <end position="1092"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="2">
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            <begin position="1099"/>
            <end position="1265"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1"/>
            <end position="525"/>
        </location>
    </feature>
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            <begin position="580"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1295"/>
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    </feature>
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            <begin position="1411"/>
            <end position="1431"/>
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    </feature>
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        <location>
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    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA49819.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1574" mass="173573" checksum="BAE0FB785E33C129" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N724</accession>
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        <recommendedName>
            <fullName evidence="14">Zinc homeostasis factor 1</fullName>
        </recommendedName>
    </protein>
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        <name evidence="12" type="ORF">MGG_03634</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
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        <property type="entry name" value="Cation_efflux_CTD"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ZT_dimer"/>
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        <property type="match status" value="1"/>
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    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="5" id="KW-0862">Zinc</keyword>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA49937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="57608" checksum="0E115801AA82B22A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>G4N763</accession>
    <name>G4N763_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06472</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717092.1">
        <property type="nucleotide sequence ID" value="XM_003717044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N763"/>
    <dbReference type="SMR" id="G4N763"/>
    <dbReference type="FunCoup" id="G4N763">
        <property type="interactions" value="813"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N763"/>
    <dbReference type="GeneID" id="2684627"/>
    <dbReference type="KEGG" id="mgr:MGG_06472"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06472"/>
    <dbReference type="eggNOG" id="KOG0183">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035750_4_0_1"/>
    <dbReference type="InParanoid" id="G4N763"/>
    <dbReference type="OMA" id="ICMLDHH"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042175">
        <property type="term" value="C:nuclear outer membrane-endoplasmic reticulum membrane network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03755">
        <property type="entry name" value="proteasome_alpha_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000004">
        <property type="entry name" value="Proteasome subunit alpha type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA50773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="269" mass="29356" checksum="E131C360B823EAB0" modified="2011-12-14" version="1">MASGYDRALSVFSPDGHVFQVEYAGEAVKRGTCAVGVKGADIVVLGCEKRSAMKLQDTRITPSKIGLIDTHVCLAFAGLNADARILVDKARLEAQSHRLTVEDPVTIEYITKYVAGVQQRYTQSGGVRPFGISTLVVGFDNGSKVPRLYQTEPSGIYSAWKANAIGRSSKTVREFLERNYKEDMDREQTIRLAIKSLLEVVQTGAKNIEIAIMAPGKSIEMLPVEDIENYVKNIEQEKQEEAAKKKTGRTPGTGSAAILTREAGSSDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7B0</accession>
    <name>G4N7B0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">INSIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06428</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the INSIG family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717139.1">
        <property type="nucleotide sequence ID" value="XM_003717091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7B0"/>
    <dbReference type="STRING" id="242507.G4N7B0"/>
    <dbReference type="GeneID" id="2684583"/>
    <dbReference type="KEGG" id="mgr:MGG_06428"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06428"/>
    <dbReference type="eggNOG" id="ENOG502S4EI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039316_1_0_1"/>
    <dbReference type="InParanoid" id="G4N7B0"/>
    <dbReference type="OMA" id="YGVITVH"/>
    <dbReference type="OrthoDB" id="205546at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025929">
        <property type="entry name" value="INSIG_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301">
        <property type="entry name" value="INSULIN-INDUCED GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301:SF3">
        <property type="entry name" value="PROTEIN NSG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07281">
        <property type="entry name" value="INSIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="97"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="48198" checksum="92BECA7E32D48E9A" modified="2011-12-14" version="1">MPADTTPPAIIRPIPRRPFNPSLTSASPPDDVSALDSQPVRNGDSASSLRSSLLDPKPRSSSQFSADTPEETDPASISRTQSILNLTQSALFGIYSPTMTGNSKSRSNPYSDRTEPGTPWGTGAQTPGRPGLYHPNVEEDDPERAEALLQLRERLGAASKSQNGGMLTGPMSPTGAHFETETALPAPHTMGSVDLLTLTAKAVLLFVLGACYGMVVYRLRDEHMSASLQQHQQRHANSFFPAKGSYDKIYIAFWGASGVLLGSLLPWFDQFCDRTLGAKTNSGCSMSTEEVKDVPTLDTDWALVIRGVGCFAGIAFAIRKLPWDSTMQVSLTLALVNPFLWYLIDRSKSGFMLASAVGVIGATVIAGLDPDMMPTPMLYDTAGMPLPRGSDQGRAAQLALGGLARRATLEAAIWMLSVLFCSCVCFGNIGRRLALNTGTPERGRWAGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7W9</accession>
    <name>G4N7W9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_06340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.2.9" evidence="1"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717242.1">
        <property type="nucleotide sequence ID" value="XM_003717194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7W9"/>
    <dbReference type="SMR" id="G4N7W9"/>
    <dbReference type="GeneID" id="2684495"/>
    <dbReference type="KEGG" id="mgr:MGG_06340"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06340"/>
    <dbReference type="eggNOG" id="ENOG502SUVS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048475_1_1_1"/>
    <dbReference type="InParanoid" id="G4N7W9"/>
    <dbReference type="OMA" id="EVMRKSI"/>
    <dbReference type="OrthoDB" id="2924818at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003839">
        <property type="term" value="F:gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017939">
        <property type="entry name" value="G-Glutamylcylcotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935:SF0">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="33"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA50923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="224" mass="24530" checksum="815647C6FD69CC2C" modified="2011-12-14" version="1">MSSPISSSGFSTPSSFTGGLPMARRTMQRSAYYFAYGSNISPTQMESRCPGSIAKGLALLPDWSFIVNERGFANVIPTGALAHEVDVMRRKGSLSPVAESLEIGAEEGVWGVLYHLCPEDEKMLDITEGAGFACIKYYADVEVLLPARPRSTGSSSTSSSESEAEANSYMVPALIYVDRHRVKPSMPREDYVARMNRGIEEAQARYGLPEGYVQRAIRPFIPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8M3</accession>
    <name>G4N8M3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716536.1">
        <property type="nucleotide sequence ID" value="XM_003716488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8M3"/>
    <dbReference type="GeneID" id="2676951"/>
    <dbReference type="KEGG" id="mgr:MGG_03404"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03404"/>
    <dbReference type="eggNOG" id="ENOG502RJMG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1441140_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8M3"/>
    <dbReference type="OMA" id="NSTRMEI"/>
    <dbReference type="OrthoDB" id="3553044at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="181" mass="19864" checksum="ECBBDB09FFBAC1ED" modified="2011-12-14" version="1">MPSFIRSRAESATSYTSRSTTWSTSSSDDDAITPVTQDSFLPPPMPAAAVPAASETPALELRRPASAAGSMDSRSSSSSTATSSSSSSSLCPAVDAADLWRRMLAVQRIYHCYNSARISAALDNEVLQKRIPSRACLDLLNDGISHLPEDEKQQVVYFIEHGKVQQRKSRSFWRRRLVRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8T3</accession>
    <name>G4N8T3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_10112</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <dbReference type="Proteomes" id="UP000009058">
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="match status" value="1"/>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    </reference>
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        <property type="entry name" value="Znf_CCCH"/>
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        <property type="entry name" value="Znf_CCCH_sf"/>
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        <property type="entry name" value="RAD201"/>
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        <property type="entry name" value="SI:CH211-113E8.11"/>
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    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
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            <begin position="184"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
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    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="353"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
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            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="395"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="408"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="477"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="614" mass="62319" checksum="701100D5F1191CCA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2025-06-18" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N954</accession>
    <name>AUH1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylglutaconyl-CoA hydratase 1, mitochondrial</fullName>
            <ecNumber evidence="6">4.2.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AUH1</name>
        <name type="ORF">MGG_03335</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2021" name="Environ. Microbiol." volume="23" first="774" last="790">
            <title>Transcription factor MoMsn2 targets the putative 3-methylglutaconyl-CoA hydratase-encoding gene MoAUH1 to govern infectious growth via mitochondrial fusion/fission balance in Magnaporthe oryzae.</title>
            <authorList>
                <person name="Xiao Y."/>
                <person name="Liu L."/>
                <person name="Zhang T."/>
                <person name="Zhou R."/>
                <person name="Ren Y."/>
                <person name="Li X."/>
                <person name="Shu H."/>
                <person name="Ye W."/>
                <person name="Zheng X."/>
                <person name="Zhang Z."/>
                <person name="Zhang H."/>
            </authorList>
            <dbReference type="PubMed" id="32431008"/>
            <dbReference type="DOI" id="10.1111/1462-2920.15088"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <scope>SUBCELLULAR LOCATION</scope>
    </reference>
    <comment type="function">
        <text evidence="1 3">3-methylglutaconyl-CoA hydratase that catalyzes the fifth step in the leucine degradation pathway, the reversible hydration of 3-methylglutaconyl-CoA (3-MG-CoA) to 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) (By similarity). Involved in vegetative growth, conidiation and in the stress response (PubMed:32431008). Controls mitochondrial morphology and mitophagy, which are critical for the infectious growth of the pathogen (PubMed:32431008).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3S)-3-hydroxy-3-methylglutaryl-CoA = 3-methyl-(2E)-glutaconyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:21536"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57346"/>
            <dbReference type="EC" id="4.2.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="3">Exhibits a reduction in growth rate and an increase in the number of conidia (PubMed:32431008). Reduces virulence in host rice plants (PubMed:32431008). Increases tolerance to NaCl, KCl and sorbitol but decreases tolerance to SDS, calcofluor-white and H(2)O(2) (PubMed:32431008).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.18" evidence="6"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716617.1">
        <property type="nucleotide sequence ID" value="XM_003716569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N954"/>
    <dbReference type="SMR" id="G4N954"/>
    <dbReference type="STRING" id="242507.G4N954"/>
    <dbReference type="EnsemblFungi" id="MGG_03335T0">
        <property type="protein sequence ID" value="MGG_03335T0"/>
        <property type="gene ID" value="MGG_03335"/>
    </dbReference>
    <dbReference type="GeneID" id="2676886"/>
    <dbReference type="KEGG" id="mgr:MGG_03335"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03335"/>
    <dbReference type="eggNOG" id="KOG1679">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_6_1"/>
    <dbReference type="InParanoid" id="G4N954"/>
    <dbReference type="OMA" id="YEQAHAW"/>
    <dbReference type="OrthoDB" id="410701at2759"/>
    <dbReference type="UniPathway" id="UPA00363">
        <property type="reaction ID" value="UER00862"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004490">
        <property type="term" value="F:methylglutaconyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000058">
        <property type="entry name" value="Enoyl-CoA hydratase/isomerase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF171">
        <property type="entry name" value="SD19268P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0809">Transit peptide</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <feature type="transit peptide" description="Mitochondrion" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000462291" description="Methylglutaconyl-CoA hydratase 1, mitochondrial">
        <location>
            <begin position="38"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q13825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="32431008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="4">
        <source>
            <dbReference type="PubMed" id="32431008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <evidence type="ECO:0000305" key="6">
        <source>
            <dbReference type="PubMed" id="32431008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="349" mass="37506" checksum="5B53E76A8CB32569" modified="2011-12-14" version="1" precursor="true">MPPVSRILSYAPRVAIRPSSQLARPARAFAVGTVRYYSAEQPEEPLIRVTDLPAPNSGHIRVLELNRPKARNAISRALLASLREEVHSIARQYDAQTGEEIPTPSWNKRFGGIAGDSEKGPTRALVLASAVESSFCAGADLKERRGFTQEETNEFLANLRSTFAALDALPIPTISAISSRALGGGLELALCTHFRVLTSNAIVSLPETRLGIIPGAGGTHRLPRLIGLGRARDMIVTGRAVSGAEAYFLGLADRLVEVLPPDEQEAADTTDKDAALLSAAREAALTEAVRLASQICEGGPIGIRAALQAVQAPSQETENKMYERVIGTEDRNEALKAFAEKRKPVFKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9X8</accession>
    <name>G4N9X8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Seryl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_03230</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716749.1">
        <property type="nucleotide sequence ID" value="XM_003716701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9X8"/>
    <dbReference type="SMR" id="G4N9X8"/>
    <dbReference type="FunCoup" id="G4N9X8">
        <property type="interactions" value="836"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9X8"/>
    <dbReference type="GeneID" id="2676464"/>
    <dbReference type="KEGG" id="mgr:MGG_03230"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03230"/>
    <dbReference type="eggNOG" id="KOG2509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023797_4_3_1"/>
    <dbReference type="InParanoid" id="G4N9X8"/>
    <dbReference type="OMA" id="EQNCIDR"/>
    <dbReference type="OrthoDB" id="10264585at2759"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070158">
        <property type="term" value="P:mitochondrial seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000069">
        <property type="entry name" value="Seryl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
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    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="262"/>
            <end position="521"/>
        </location>
    </feature>
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        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA50430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="536" mass="59727" checksum="38E73A1AEBA9CC3B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA35</accession>
    <name>G4NA35_PYRO7</name>
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        <recommendedName>
            <fullName evidence="3">TLDc domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name type="synonym">Magnaporthe oryzae</name>
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            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_09752"/>
    <dbReference type="eggNOG" id="ENOG502SPCI">
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    </dbReference>
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    <dbReference type="InParanoid" id="G4NA35"/>
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    <dbReference type="OrthoDB" id="5343429at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="61391" checksum="787209D9761CFA1F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAI3</accession>
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        <recommendedName>
            <fullName evidence="4">DUF1742-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09711</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003717592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAI3"/>
    <dbReference type="GeneID" id="2680665"/>
    <dbReference type="KEGG" id="mgr:MGG_09711"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09711"/>
    <dbReference type="eggNOG" id="ENOG502S7NV">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_088285_2_0_1"/>
    <dbReference type="InParanoid" id="G4NAI3"/>
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        <property type="component" value="Chromosome 4"/>
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    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:vacuolar transport"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28218:SF1">
        <property type="entry name" value="VPS4-ASSOCIATED PROTEIN 1"/>
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            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA51321.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="22386" checksum="E12857FE6BBB7F42" modified="2011-12-14" version="1">MSSSPFPNVYTHRKVADTASKGCNICYKPTTSVLITPEKQDFFYVCAIHLKDKNFATPIIDHAAIEARLKAEAEAKKKKELDEEVERVKKEYAEKQKAKAEKDDKGKDKDQKEQDKDKAQPDSKKEETPKPEDKAKEASPTAATAVSSADEEPRVFALARSFYNQRIDKKRQIEMAKRNRERIQNPSFFPSVPKGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAJ6</accession>
    <name>G4NAJ6_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17282</name>
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    <organism evidence="2 3">
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717653.1">
        <property type="nucleotide sequence ID" value="XM_003717605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAJ6"/>
    <dbReference type="GeneID" id="12986593"/>
    <dbReference type="KEGG" id="mgr:MGG_17282"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17282"/>
    <dbReference type="HOGENOM" id="CLU_1057971_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAJ6"/>
    <dbReference type="OrthoDB" id="10616800at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="263" mass="28456" checksum="FE8E11E08C7B4446" modified="2011-12-14" version="1">MVGFHTRLTESRRPVEMHHTAAILEWKASASSRRAFVIPKEPNWPLANAGSAAEVTSPLLVIGDEHPLVLGLRVLYLTVAAVEIRRSTRLPGPDAQRPPLIFFGAAQEDGPGDSCRQSAAELAARKDTGVLPRTHTHTHTCGVFLAPPLFVTAEPFSVGLDVACRQVTFCLDSSGNEGVRGPLPCTTYSTVQRSIFATTNRNWQIVLYTPRYVCTVWYTKFENQGCTAVVLRPSESAAHESPSMLSGTANQAGPADPHARLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBB9</accession>
    <name>G4NBB9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_00580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718465.1">
        <property type="nucleotide sequence ID" value="XM_003718417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBB9"/>
    <dbReference type="GeneID" id="2675093"/>
    <dbReference type="KEGG" id="mgr:MGG_00580"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00580"/>
    <dbReference type="HOGENOM" id="CLU_1315609_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBB9"/>
    <dbReference type="OMA" id="PKDADGM"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="209" mass="23182" checksum="48174EFDD6347D9D" modified="2011-12-14" version="1">MAAESKPALFLLKRGPRCPIPLTSPAQDLREAIAKNEELAANLSESDKSLHEAIKDVVVLSINLNEISKRLTFNNNGNKEGNRDQVVASQISPDELVNLKKEIHAEVQTLVRTEVSQLKHDHAAEMGTMASQAAHFEASLSSAFCSRDFHNTRLNRIEGKLNEINLLDFPAKIRGLEAELKAVRDELRELKEKQLPKDADGMCPSHTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBL0</accession>
    <name>G4NBL0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717699.1">
        <property type="nucleotide sequence ID" value="XM_003717651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBL0"/>
    <dbReference type="GeneID" id="12986602"/>
    <dbReference type="KEGG" id="mgr:MGG_17298"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17298"/>
    <dbReference type="InParanoid" id="G4NBL0"/>
    <dbReference type="OrthoDB" id="5250150at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="123" mass="13844" checksum="CCD4983688E190FF" modified="2011-12-14" version="1" fragment="single">AWATASQQDNDSPRQPLDSAPPLPSRYRLREEKYRPTQSQDQRMLVDLTTDDTGFRCSRCTQIFNSSDNCFALSGCGCVPCQADRKERDGGPCPCCKEHVEDVLLLEWKPLGLERMVDVSAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBQ9</accession>
    <name>G4NBQ9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718551.1">
        <property type="nucleotide sequence ID" value="XM_003718503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBQ9"/>
    <dbReference type="GeneID" id="12984118"/>
    <dbReference type="KEGG" id="mgr:MGG_17443"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17443"/>
    <dbReference type="HOGENOM" id="CLU_2386602_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBQ9"/>
    <dbReference type="OrthoDB" id="5216226at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="94" mass="10403" checksum="61DAED31C03F46A3" modified="2011-12-14" version="1">MFLTPAISLPTAPMPGVPRLVPGLVLSRRAVRQESSHALQEQHKTHMKRVLPTDIVIVTNKARARCNLPVWYARFSWPRTHPGTTPPGGSVMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCH6</accession>
    <name>G4NCH6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Peroxisomal membrane protein PEX14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Peroxin-14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_01081</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peroxin-14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717857.1">
        <property type="nucleotide sequence ID" value="XM_003717809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCH6"/>
    <dbReference type="SMR" id="G4NCH6"/>
    <dbReference type="STRING" id="242507.G4NCH6"/>
    <dbReference type="GeneID" id="2674206"/>
    <dbReference type="KEGG" id="mgr:MGG_01081"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01081"/>
    <dbReference type="eggNOG" id="ENOG502S3Q3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044743_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCH6"/>
    <dbReference type="OMA" id="CDGLIYS"/>
    <dbReference type="OrthoDB" id="441517at2759"/>
    <dbReference type="PHI-base" id="PHI:4000"/>
    <dbReference type="PHI-base" id="PHI:6874"/>
    <dbReference type="PHI-base" id="PHI:9784"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025655">
        <property type="entry name" value="PEX14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006785">
        <property type="entry name" value="Pex14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058:SF5">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04695">
        <property type="entry name" value="Pex14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0811">Translocation</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peroxisome membrane anchor protein Pex14p N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="66"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="202"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA48273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="366" mass="39251" checksum="9B53C14DC63514C4" modified="2011-12-14" version="1">MADPDKKEDVPVPAWQQQQSNDGSTLDHARLFLQDEEVRQASREKKISFLRSKGVSGADIEILLGEDESSSITSDSNQTTAAAPHSAQEKPTASQPQLPPQPQMQQQQQPQQQTQPAQKPDQPPIVTYPEFLTKPPRPPPLITATTFLNTASAFAGLATLIIGTSKYVLSPMVESLTDARIDLHRSASDGLSRTIEKLEGIVSEVPPLPSASTQDKTGGAARKQDDNDAASSDGGDPTELFHRDVGVQTSPPQTPFAATASTQKPSAIESQATRLAKLTASVREMSVSYATTAETHESTSVVLGHLSADVDKLRTPVATRPAGTVYYRAFAEPDDQVKAVKQSIRSVKGVLLSARSFPPPQGSTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCI2</accession>
    <name>G4NCI2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_01075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717863.1">
        <property type="nucleotide sequence ID" value="XM_003717815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCI2"/>
    <dbReference type="SMR" id="G4NCI2"/>
    <dbReference type="GeneID" id="2674793"/>
    <dbReference type="KEGG" id="mgr:MGG_01075"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01075"/>
    <dbReference type="HOGENOM" id="CLU_1825671_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCI2"/>
    <dbReference type="OrthoDB" id="5222505at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="15945" checksum="F45782626FA5530C" modified="2011-12-14" version="1">MSTTQEKGQRYSVLVSCTLHDGKTDEYLAIMEKVIAYLSKEEPDFLHIEIMRVDGSPNKLRYLEHWAKPFDVLAKDTASNPQLNEFMNAMDPLLAEKRSVEFLRSFGGPWARTRDGTFSKIRCMLTPPGEASLLSLPGAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCT5</accession>
    <name>G4NCT5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Delta(24)-sterol reductase</fullName>
            <ecNumber evidence="2">1.3.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_01030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.3.1.72" evidence="2"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717912.1">
        <property type="nucleotide sequence ID" value="XM_003717864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCT5"/>
    <dbReference type="SMR" id="G4NCT5"/>
    <dbReference type="STRING" id="242507.G4NCT5"/>
    <dbReference type="GeneID" id="2674160"/>
    <dbReference type="KEGG" id="mgr:MGG_01030"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01030"/>
    <dbReference type="eggNOG" id="KOG1262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025883_0_0_1"/>
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    <dbReference type="OMA" id="WVGRSAF"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
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    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:Delta24(24-1) sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:Delta24-sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000031">
        <property type="entry name" value="FAD binding domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040165">
        <property type="entry name" value="Diminuto-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801">
        <property type="entry name" value="24-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10801:SF10">
        <property type="entry name" value="FAD BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14300)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="26"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="585" mass="65503" checksum="74C57B7C46C7238C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND32</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">MGG_17332</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Ascomycota</taxon>
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            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717958.1">
        <property type="nucleotide sequence ID" value="XM_003717910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND32"/>
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    <dbReference type="KEGG" id="mgr:MGG_17332"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17332"/>
    <dbReference type="HOGENOM" id="CLU_2923103_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND32"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="61" mass="6670" checksum="ABF4131BF3C2A9D6" modified="2011-12-14" version="1">MATSLQGKPRIRQKQGPSYTVRARLKPGAKCLPQLFSRSEGAHGEANKPPSPYVKGHVTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND77</accession>
    <name>G4ND77_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718799.1">
        <property type="nucleotide sequence ID" value="XM_003718751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND77"/>
    <dbReference type="GeneID" id="5049802"/>
    <dbReference type="KEGG" id="mgr:MGG_14703"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14703"/>
    <dbReference type="eggNOG" id="ENOG502S098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1960012_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND77"/>
    <dbReference type="OrthoDB" id="5093543at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="128" mass="15036" checksum="0461CA9E3C18B9FA" modified="2011-12-14" version="1">MSPQQAFDYMHVHDQKDKKLWYDFGPEPEAKISEKDFRKQFRHMDFDSVLQYVAFPRIELGKDADEGENETDELHRGRQDTISLFKWLREEGVKQIVRVKVDDMEMPCHSDEAIEEALAGFDVEAALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND80</accession>
    <name>G4ND80_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ankyrin repeat domain-containing protein 28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00291</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA49218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718802.1">
        <property type="nucleotide sequence ID" value="XM_003718754.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4ND80"/>
    <dbReference type="GeneID" id="2674145"/>
    <dbReference type="KEGG" id="mgr:MGG_00291"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00291"/>
    <dbReference type="eggNOG" id="KOG2029">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001836_2_0_1"/>
    <dbReference type="InParanoid" id="G4ND80"/>
    <dbReference type="OMA" id="WRATWLN"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02249">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="1002"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="1068"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="1139"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="1271"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="1304"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
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            <end position="1407"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
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            <end position="1481"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="1567"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="8">
        <location>
            <begin position="1666"/>
            <end position="1692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1724"/>
            <end position="1772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1733"/>
            <end position="1750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS01357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1772" mass="195352" checksum="3CC79E658D105DD1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDE8</accession>
    <name>G4NDE8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003718021.1">
        <property type="nucleotide sequence ID" value="XM_003717973.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NDE8"/>
    <dbReference type="SMR" id="G4NDE8"/>
    <dbReference type="STRING" id="242507.G4NDE8"/>
    <dbReference type="ESTHER" id="mago7-a4rdm3">
        <property type="family name" value="AHL-acylase"/>
    </dbReference>
    <dbReference type="GeneID" id="2674684"/>
    <dbReference type="KEGG" id="mgr:MGG_00931"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00931"/>
    <dbReference type="eggNOG" id="ENOG502SG5G">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_2_1"/>
    <dbReference type="InParanoid" id="G4NDE8"/>
    <dbReference type="OMA" id="YSMEGYA"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="37"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="348" mass="36479" checksum="B9C43BFE30E478F0" modified="2011-12-14" version="1">MPTPQTQTIPTPWCPISATILQPDPTTTPPHPTDLTLLLLHGNSSSSLAFTHILSRPPPPGVSRVVALDYPGHGRSGNATAEHQRVYTQPGYAAVAAHALAALNIRGRVAVLGWSLGGHVAIELIPLLAPSSLADRAASLGTGPLPGTSPAPSPPPTSEIAIAGIMLVGTPPLGNAAQFKAGFSPGAGECASARESRRGEVGRGGRDALSEISFFALAAEELTDEMVETLTVAGHGPPREQWMADGARRTDGRARRVMAENAFAGELSDQVGIVGASDVLCAVVNGAEEPFVNLDYVDGIRFRNLWKGECHRIPGLGHAPFWEAPDLFWDGYLTPFLADCDAAQAYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEQ6</accession>
    <name>G4NEQ6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719063.1">
        <property type="nucleotide sequence ID" value="XM_003719015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEQ6"/>
    <dbReference type="SMR" id="G4NEQ6"/>
    <dbReference type="GeneID" id="2675043"/>
    <dbReference type="KEGG" id="mgr:MGG_00077"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00077"/>
    <dbReference type="HOGENOM" id="CLU_420376_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEQ6"/>
    <dbReference type="OrthoDB" id="5228430at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="652" mass="70637" checksum="C30B8C0DB4C1A317" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NER5</accession>
    <name>G4NER5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_00070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719072.1">
        <property type="nucleotide sequence ID" value="XM_003719024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NER5"/>
    <dbReference type="SMR" id="G4NER5"/>
    <dbReference type="STRING" id="242507.G4NER5"/>
    <dbReference type="GeneID" id="2675077"/>
    <dbReference type="KEGG" id="mgr:MGG_00070"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00070"/>
    <dbReference type="eggNOG" id="ENOG502RK4V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1185207_0_0_1"/>
    <dbReference type="InParanoid" id="G4NER5"/>
    <dbReference type="OrthoDB" id="5227456at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053187">
        <property type="entry name" value="Notoamide_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256:SF1">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47256">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="58"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="158"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="215"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="234" mass="25913" checksum="DFD940C662533570" modified="2011-12-14" version="1">MSGSGRFRALRPLDESTALQANEVDAVREGSASSVSLSPMLPSSSSAPVRTQNRTLSACLRCRRSKAKCTGTRPRCRRCSDNDVSCEYDADPDITPSLTVKRRNIELLKENQELRQVIGFMATRPWQETEEVFQRLREGMDPLEVYAALIAGRTEGSGGLVTSTLQHPSSQHRPPVESGWDSRGGLRPPPPRGEVRGLGMQQQGQEQEQQTTEGRTSRDPRRPLERLDIASLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF76</accession>
    <name>G4NF76_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EKC/KEOPS complex subunit CGI121</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">EKC/KEOPS complex subunit cgi121</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_17668</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the CGI121/TPRKB family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA47223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719590.1">
        <property type="nucleotide sequence ID" value="XM_003719542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF76"/>
    <dbReference type="SMR" id="G4NF76"/>
    <dbReference type="FunCoup" id="G4NF76">
        <property type="interactions" value="498"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NF76"/>
    <dbReference type="GeneID" id="12986079"/>
    <dbReference type="KEGG" id="mgr:MGG_17668"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17668"/>
    <dbReference type="eggNOG" id="KOG4066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065847_1_0_1"/>
    <dbReference type="InParanoid" id="G4NF76"/>
    <dbReference type="OMA" id="IVCRMST"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2380.10">
        <property type="entry name" value="CGI121/TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013926">
        <property type="entry name" value="CGI121/TPRKB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036504">
        <property type="entry name" value="CGI121/TPRKB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840">
        <property type="entry name" value="CGI-121 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840:SF10">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08617">
        <property type="entry name" value="CGI-121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143870">
        <property type="entry name" value="PF0523-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA47223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="231" mass="24455" checksum="A2CF775BB5D5D1E8" modified="2011-12-14" version="1">MSAPAIDPAGGDGPAISPIDTTNSDTPTTTQLPSLLSQIPLEHIPSTHTVHAALFRDVSNAAHLHSQLLARNPAFEYALIDASAVASTAQVLAAVFRALTALLGGGLRTPNVHSETVFCLSPSNNITEAYRRFGISPSTKDVIVIKVLFPAEDAENAAPSPADVWAHLCANVQGTALPFTDESISPLIDWAKVRKYYKLNAAPALAGLKNEDIKRKESEMLILGAMALRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFK8</accession>
    <name>G4NFK8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719182.1">
        <property type="nucleotide sequence ID" value="XM_003719134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFK8"/>
    <dbReference type="GeneID" id="12985173"/>
    <dbReference type="KEGG" id="mgr:MGG_15381"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15381"/>
    <dbReference type="HOGENOM" id="CLU_100714_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFK8"/>
    <dbReference type="OrthoDB" id="5064119at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="213" mass="23987" checksum="2A9D68F0C094D796" modified="2011-12-14" version="1">MAHVPQAPQTPATNPLGNQAWRHIVSQENVPESFVNGFWYQLLRHHFPFPEFIICPEAHVARAAGGGETLRADLLVLQVRPGRTDGYQTRVILAFEGKKGSRTERAFLSHTPQLSNYTSSCTPLVGRKFGALASGPRFLIMAWTQASRHDDIRQITQQEGRIPESLDRIMVQDVNIQDQREGLDRILHYIHTQATTAASRQDRNGWSAATWPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGM9</accession>
    <name>G4NGM9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mmc1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719756.1">
        <property type="nucleotide sequence ID" value="XM_003719708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGM9"/>
    <dbReference type="SMR" id="G4NGM9"/>
    <dbReference type="STRING" id="242507.G4NGM9"/>
    <dbReference type="GeneID" id="2677511"/>
    <dbReference type="KEGG" id="mgr:MGG_04082"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04082"/>
    <dbReference type="eggNOG" id="ENOG502RY8K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023613_1_0_1"/>
    <dbReference type="InParanoid" id="G4NGM9"/>
    <dbReference type="OMA" id="WAERAHT"/>
    <dbReference type="OrthoDB" id="5319015at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056196">
        <property type="entry name" value="Mmc1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38644">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38644:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23868">
        <property type="entry name" value="Mmc1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23867">
        <property type="entry name" value="Mmc1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mmc1 C-terminal" evidence="1">
        <location>
            <begin position="394"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="637" mass="68448" checksum="1671A440EF9798D6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH36</accession>
    <name>G4NH36_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UBA domain-containing protein Ucp14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03951</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719913.1">
        <property type="nucleotide sequence ID" value="XM_003719865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH36"/>
    <dbReference type="FunCoup" id="G4NH36">
        <property type="interactions" value="12"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NH36"/>
    <dbReference type="GeneID" id="2677334"/>
    <dbReference type="KEGG" id="mgr:MGG_03951"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03951"/>
    <dbReference type="eggNOG" id="KOG4463">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057574_0_0_1"/>
    <dbReference type="InParanoid" id="G4NH36"/>
    <dbReference type="OMA" id="RYRQFWR"/>
    <dbReference type="OrthoDB" id="272778at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013861">
        <property type="entry name" value="TMEM115/Pdh1/Rbl19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF21">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08551">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01160">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA47546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="30478" checksum="12A058BE4149CD14" modified="2011-12-14" version="1">MSFANAPVTRSLVLGLVVTSIGATLFDVKHYFYLLIDPHILRYHQPWRALLFQLCYTNSSEVLFAAMCLYNMRIIERIWGSRKYASFVVVAGALTTLMLPMLVLVLRTLTFGAFNYLPAGPTPILFAILAQYHAAVPHVYQYRLALSAAPPTDEQFVGVTFSNKSYKYFLAIQLALSQWPGSLLSAVVGWTIGYAWRTDLLPGSLTKWRVPGWLVGMRTARRRQEFDGLRRRLEDEDVTGAASGSQVAQDTDAGRRRTVGQQIFDEFRGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHL2</accession>
    <name>G4NHL2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720089.1">
        <property type="nucleotide sequence ID" value="XM_003720041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHL2"/>
    <dbReference type="GeneID" id="2677137"/>
    <dbReference type="KEGG" id="mgr:MGG_03807"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03807"/>
    <dbReference type="eggNOG" id="ENOG502T7XE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1219899_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHL2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="227" mass="23876" checksum="C3E0B696D61AE946" modified="2011-12-14" version="1">MSGRSILPTIAPPAWPPQPQSSSWPVSPTVVDGWSQGHAANQTVLGYFAIASIRTMFTFAGILFLSPFVESLPQTANIIAFVLLIAELLTAYRSLKARNVEVNRAWTVANLACFVGVFVWLLVGSVAPASLEPWPPGADSKGEPAPLVSRIPTIWAFLGTIAAGFTLPAVRVQDWRSGLGVDKFPSLDSPVYSPASTAVALGLNGSVDGPAALQQTYSGTSDSGPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIE2</accession>
    <name>G4NIE2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_09865</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720369.1">
        <property type="nucleotide sequence ID" value="XM_003720321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIE2"/>
    <dbReference type="GeneID" id="2680822"/>
    <dbReference type="KEGG" id="mgr:MGG_09865"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09865"/>
    <dbReference type="eggNOG" id="ENOG502SMK9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_585352_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIE2"/>
    <dbReference type="OMA" id="LKPHEMM"/>
    <dbReference type="OrthoDB" id="3934549at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="44"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="467" mass="51413" checksum="CA19EEB33D3F9430" modified="2011-12-14" version="1">MHYPTPDVIASWPPPNYTNPQRRGPALLAIELTILPIALVTLLLRLYVRIRIVKSYGWDDWLMVAAAACGLGVTLCTIIATQVFNWNAHIWDLTSDQMVQGRKVSLASQTLFAAATSLAKASILLSYLRIAPQKSWFRRLTFSALALVSTIGFAAISLFWTQCTPISSYWFLQDPSQAVNCEVDEGLLDFAQALCNVCTDLIVYVLPIPTLAALSLPLGQRIATIALFSLGLIVVVAGCMRAYWISYVVVADLPDFTWEGYHLWIWTAVECQLSVICGCVPVLKPLFLMMLGREAGFELRREDIDDDVADFDFCDIATTRDSKAYTMYARSVHSSHTNASAIEAPPAARNTNRFSFVWASSDGLARTNVVVETVDVAAATAAASDPWYPGTRPAFIPGMPPPPRPPRSPLPPEMENGMYLAEICKRHTMPNLRDDDADVWVSATGGVRTVITAGVPIKPKAKSLRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJX4</accession>
    <name>G4NJX4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721246.1">
        <property type="nucleotide sequence ID" value="XM_003721198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJX4"/>
    <dbReference type="SMR" id="G4NJX4"/>
    <dbReference type="GeneID" id="5050537"/>
    <dbReference type="KEGG" id="mgr:MGG_12664"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12664"/>
    <dbReference type="eggNOG" id="KOG3043">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_2_1_1"/>
    <dbReference type="InParanoid" id="G4NJX4"/>
    <dbReference type="OMA" id="DPYEKWA"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="258" mass="28447" checksum="F063663982F88A78" modified="2011-12-14" version="1">MEKVLAKPTDLCCIQGGAIHTGEATGTVEQIEGVDTYIARPPPEKANGNVLLFFPDAFGMHLKSFLMMDAFAQHGYLTLGVDYFLGDGVGKHSSTPLADPTFDFKAWVDKHLGASEEVAKRWVQDVKAKYGTDGNVKFACVGYCWGARFVARQLSAEGICKVGAVAHPSFLNESDVFGVNEPFFLSVPSIDELFEPKERSRAIEILSGGGKQFNMQIFANVGHGFATQPNPSDPYESWAKKQSFRSFVDWFDFWLSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL49</accession>
    <name>G4NL49_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside 2-deoxyribosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_02975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720725.1">
        <property type="nucleotide sequence ID" value="XM_003720677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL49"/>
    <dbReference type="SMR" id="G4NL49"/>
    <dbReference type="GeneID" id="2682528"/>
    <dbReference type="KEGG" id="mgr:MGG_02975"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02975"/>
    <dbReference type="eggNOG" id="ENOG502SJ1A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109866_0_0_1"/>
    <dbReference type="InParanoid" id="G4NL49"/>
    <dbReference type="OMA" id="YREQVEW"/>
    <dbReference type="OrthoDB" id="2893324at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039470">
        <property type="entry name" value="Nuc_deoxyri_tr2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15891">
        <property type="entry name" value="Nuc_deoxyri_tr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA45982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="20969" checksum="C72CFF3EB941D920" modified="2011-12-14" version="1">MNRFVRVSYNLLVQKSPRSTLSSSKMASQQSQVIFAPSEEPPRGVQSVFLAGTTSRVDATDWRETLSSLLSDTKITIYNPYRPDWDSTWREDVDFEPYRQQVEWELDKQEKADVVVVYFHPATQAPVSLLEFGLCARVPGKAVVYCPEGYWKRGNVQVVCRKFGVEMVESIQGLHGAIMKRMGQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-09-13" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>Q51LS1</accession>
    <accession>A4RBQ8</accession>
    <accession>G4NIV9</accession>
    <accession>Q2KFW0</accession>
    <name>ISY1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Pre-mRNA-splicing factor ISY1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">ISY1</name>
        <name type="ORF">MGCH7_ch7g575</name>
        <name type="ORF">MGG_02820</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ISY1 family.</text>
    </comment>
    <comment type="sequence caution" evidence="3">
        <conflict type="erroneous gene model prediction">
            <sequence resource="EMBL-CDS" id="EAQ71168" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71168.1"/>
        <property type="status" value="ALT_SEQ"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720918.1">
        <property type="nucleotide sequence ID" value="XM_003720870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q51LS1"/>
    <dbReference type="SMR" id="Q51LS1"/>
    <dbReference type="FunCoup" id="Q51LS1">
        <property type="interactions" value="213"/>
    </dbReference>
    <dbReference type="STRING" id="242507.Q51LS1"/>
    <dbReference type="EnsemblFungi" id="MGG_02820T0">
        <property type="protein sequence ID" value="MGG_02820T0"/>
        <property type="gene ID" value="MGG_02820"/>
    </dbReference>
    <dbReference type="GeneID" id="2682373"/>
    <dbReference type="KEGG" id="mgr:MGG_02820"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02820"/>
    <dbReference type="eggNOG" id="KOG3068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043453_2_0_1"/>
    <dbReference type="InParanoid" id="Q51LS1"/>
    <dbReference type="OMA" id="YHWERRI"/>
    <dbReference type="OrthoDB" id="1739576at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000350">
        <property type="term" value="P:generation of catalytic spliceosome for second transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.660:FF:000001">
        <property type="entry name" value="pre-mRNA-splicing factor ISY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009360">
        <property type="entry name" value="Isy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037200">
        <property type="entry name" value="Isy1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13021">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ISY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06246">
        <property type="entry name" value="Isy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140102">
        <property type="entry name" value="ISY1 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0508">mRNA splicing</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0747">Spliceosome</keyword>
    <feature type="chain" id="PRO_0000192971" description="Pre-mRNA-splicing factor ISY1">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="246" mass="28041" checksum="ED3F0C7C6EDADCA3" modified="2005-06-07" version="1">MARNSEKAQSMLFRFREAQAADLGIIDAGRTRRPRAITEQDSIPACEKWRGQVLKDISRKVSRIQESSLSDYQIRDLNDEINKLMREKHMWEVQIRNLGGPNYTRAGGAKVYDEAGKEIGGAGRGYRYFGRAKELPGVKELFEAARAKKGDEKPLEARDDLRKQVDAAYYGYSPDEEDDELLAYEAAKEKEAFENLADNRKGEQLPPGWEPLPGDNGDGKGWELPTVEEVQQELINRRKQRLLNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4E1</accession>
    <name>A0A151V4E1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_18104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845956.1">
        <property type="nucleotide sequence ID" value="XM_016990564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4E1"/>
    <dbReference type="STRING" id="242507.A0A151V4E1"/>
    <dbReference type="GeneID" id="27922188"/>
    <dbReference type="KEGG" id="mgr:MGG_18104"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18104"/>
    <dbReference type="InParanoid" id="A0A151V4E1"/>
    <dbReference type="OrthoDB" id="2630497at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KYQ30452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="49" mass="6416" checksum="E0917983CA77554D" modified="2016-06-08" version="1" fragment="single">YNIKQIFDHRRNHGKTKYFIKWENYRYKKNIWEPLNHLQNCQEPLRQYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>A4QXP8</accession>
    <name>A4QXP8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_14093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713325.1">
        <property type="nucleotide sequence ID" value="XM_003713277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4QXP8"/>
    <dbReference type="GeneID" id="5049228"/>
    <dbReference type="KEGG" id="mgr:MGG_14093"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14093"/>
    <dbReference type="HOGENOM" id="CLU_1586814_0_0_1"/>
    <dbReference type="InParanoid" id="A4QXP8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671718" evidence="2">
        <location>
            <begin position="19"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="168" mass="18509" checksum="7D2E6A3F885532F5" modified="2007-05-15" version="1">MHPKQIYTFFIFASLGIAAPVSESVDKQLPPGQKSHAPADVPTDERGPRRPSRGGIRSDGIRISGIHPDGIKISINDNNLANPRKNHRERFSQTMVQRLDGGTRTVKSEYSTSVSSGNGLTCCDGVEPCSCTGSFCCKGFGDSRRRTKKKSREQKGDTEIFTEHEVWN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-09-11" modified="2025-06-18" version="97" xmlns="https://uniprot.org/uniprot">
    <accession>A4R8D7</accession>
    <accession>G4N6X1</accession>
    <name>MCES_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>mRNA cap guanine-N(7) methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>mRNA (guanine-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>mRNA cap methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">ABD1</name>
        <name type="ORF">MGG_06505</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for methylating the 5'-cap structure of mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56" evidence="2"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717054.1">
        <property type="nucleotide sequence ID" value="XM_003717006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R8D7"/>
    <dbReference type="SMR" id="A4R8D7"/>
    <dbReference type="FunCoup" id="A4R8D7">
        <property type="interactions" value="1029"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4R8D7"/>
    <dbReference type="EnsemblFungi" id="MGG_06505T0">
        <property type="protein sequence ID" value="MGG_06505T0"/>
        <property type="gene ID" value="MGG_06505"/>
    </dbReference>
    <dbReference type="GeneID" id="2684660"/>
    <dbReference type="KEGG" id="mgr:MGG_06505"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06505"/>
    <dbReference type="eggNOG" id="KOG1975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020346_3_1_1"/>
    <dbReference type="InParanoid" id="A4R8D7"/>
    <dbReference type="OMA" id="LITGDCF"/>
    <dbReference type="OrthoDB" id="10248867at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA 5'-cap (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016899">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189:SF2">
        <property type="entry name" value="MRNA CAP GUANINE-N7 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="MRNA GUANINE-7- METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="mRNA_G-N7_MeTrfase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028762">
        <property type="entry name" value="ABD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-0506">mRNA capping</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000303911" description="mRNA cap guanine-N(7) methyltransferase">
        <location>
            <begin position="1"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA cap 0 methyltransferase" evidence="3">
        <location>
            <begin position="135"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="333"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="144"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="281"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="O43148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="486" mass="54649" checksum="E7A892734D826EFC" modified="2007-05-15" version="1">MAGGADLDEPPRQSDSTTDRKRPADSTHEIGSADVPRDRAGNKTYDISKLEPARKRQRSKSPSGEAAPRKLKRPGARATISEADRKAARERALERERLAREAATADEERQQINDVVKAHYNAVPERGRDWRKTDSRIKGLRSFNNWIKSCIIQKFSPDEDHQPGRGGGPSILVLDMGCGKGGDLGKWQQAPQHVELYVGMDPADVSIDQARDRYRSMSSRGGRGGRGGRGGGRGPARLFEARFHVKDCFGEPISDIDIIRQVGFESGPHGGGRGFDVVSMMFCMHYAFETEQKARQMLKNVAGALRKGGRLIGAIPNSDVISTKVREHNERMVEMKKKQAEAGDGSKKDDGGDAEEGELDEPEVEKSAEWGNDIYRVRFPGKTPEDGIFRPPFGWKYNFFLHEAVEEVPEYVVPWEAFRALAEDYNLELQWHRSFKEIWDQEKDDRTLGPLSERMHVRDRNTGELLVSPEELEAANFYVGFCFYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLL5</accession>
    <name>G4MLL5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06746</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709460.1">
        <property type="nucleotide sequence ID" value="XM_003709412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLL5"/>
    <dbReference type="GeneID" id="2684919"/>
    <dbReference type="KEGG" id="mgr:MGG_06746"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06746"/>
    <dbReference type="eggNOG" id="ENOG502RK47">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1835529_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLL5"/>
    <dbReference type="OMA" id="AWPIYYS"/>
    <dbReference type="OrthoDB" id="5186547at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465228" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15079" checksum="AC1CA14ADD51199F" modified="2011-12-14" version="1">MSIARILAVLALVLSLSGGVVKAWPIYYSQVSSPLSRASSQYRIDPDWAAQHVLAGSATYGLNFPGEYDYAAFYCQNLCDGTRGCKSMFTSFDSSRPAAPKSWGVCTVFDAPLEPRLYVDQSDGNFPAVGGYNKFGSPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLL7</accession>
    <name>G4MLL7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 16">Branchpoint-bridging protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MGG_06748</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the BBP/SF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709462.1">
        <property type="nucleotide sequence ID" value="XM_003709414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLL7"/>
    <dbReference type="SMR" id="G4MLL7"/>
    <dbReference type="STRING" id="242507.G4MLL7"/>
    <dbReference type="GeneID" id="2684921"/>
    <dbReference type="KEGG" id="mgr:MGG_06748"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06748"/>
    <dbReference type="eggNOG" id="KOG0119">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016864_3_0_1"/>
    <dbReference type="InParanoid" id="G4MLL7"/>
    <dbReference type="OMA" id="PGMPSMY"/>
    <dbReference type="OrthoDB" id="6777263at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000243">
        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045131">
        <property type="term" value="F:pre-mRNA branch point binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02395">
        <property type="entry name" value="KH-I_BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.60.10:FF:000030">
        <property type="entry name" value="Branchpoint-bridging protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000024">
        <property type="entry name" value="Branchpoint-bridging protein-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032570">
        <property type="entry name" value="SF1-HH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047086">
        <property type="entry name" value="SF1-HH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF45">
        <property type="entry name" value="SPLICING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16275">
        <property type="entry name" value="SF1-HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 16" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 16" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 16" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="9 16" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 14 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="19">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="19">
        <location>
            <begin position="344"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="401"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="265"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="475"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="530"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="569"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="611"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00053279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EHA56850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="638" mass="68307" checksum="30F9E12D6F074E75" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLQ7</accession>
    <name>G4MLQ7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteinase inhibitor I78</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710297.1">
        <property type="nucleotide sequence ID" value="XM_003710249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLQ7"/>
    <dbReference type="SMR" id="G4MLQ7"/>
    <dbReference type="STRING" id="242507.G4MLQ7"/>
    <dbReference type="GeneID" id="2675954"/>
    <dbReference type="KEGG" id="mgr:MGG_05437"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05437"/>
    <dbReference type="eggNOG" id="ENOG502SBMP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_162852_1_1_1"/>
    <dbReference type="InParanoid" id="G4MLQ7"/>
    <dbReference type="OMA" id="AMTMDHR"/>
    <dbReference type="OrthoDB" id="10013825at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.10">
        <property type="entry name" value="Trypsin Inhibitor V, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021719">
        <property type="entry name" value="Prot_inh_I78"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39600">
        <property type="entry name" value="PEPTIDASE INHIBITOR I78 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39600:SF1">
        <property type="entry name" value="PEPTIDASE INHIBITOR I78 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11720">
        <property type="entry name" value="Inhibitor_I78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8558" checksum="55E34C5CD873BF9C" modified="2011-12-14" version="1">MPLVVPGVQTEASSADKTEEFTMKLAGKKIDEIDKDKDLPKEHRIIHPGQMVTKDYNPDRLNVHVDDNGIVSHVAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM10</accession>
    <name>G4MM10_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06788</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709507.1">
        <property type="nucleotide sequence ID" value="XM_003709459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM10"/>
    <dbReference type="SMR" id="G4MM10"/>
    <dbReference type="GeneID" id="2684961"/>
    <dbReference type="KEGG" id="mgr:MGG_06788"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06788"/>
    <dbReference type="eggNOG" id="ENOG502SIFH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030732_0_0_1"/>
    <dbReference type="InParanoid" id="G4MM10"/>
    <dbReference type="OMA" id="GWCAVEA"/>
    <dbReference type="OrthoDB" id="423576at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="617" mass="69244" checksum="A930854D83E756C8" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMV4</accession>
    <name>G4MMV4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708796.1">
        <property type="nucleotide sequence ID" value="XM_003708748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMV4"/>
    <dbReference type="SMR" id="G4MMV4"/>
    <dbReference type="GeneID" id="12985678"/>
    <dbReference type="KEGG" id="mgr:MGG_16012"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16012"/>
    <dbReference type="eggNOG" id="ENOG502SRF5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089032_1_1_1"/>
    <dbReference type="InParanoid" id="G4MMV4"/>
    <dbReference type="OMA" id="QREYCDS"/>
    <dbReference type="OrthoDB" id="5209718at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="202" mass="22918" checksum="D212CDC18B0B7D98" modified="2011-12-14" version="1">MTENMPPGRQSNTERRRIRDDCRKRLADHIYDSLGLQVKPADVRLLPRGSDFYRWRVLPGNEEICSKIFSKSLSDHSVNALRLLREEVGKSFEAIGTSESPNLNSQKPSSLISQLQNENAQLSDQLRAVAGELATERDHRSDLEEENQSLRSTQSLLEKKLQDQIDIAENFRSVLARCATVLPVLENMRKQMAESLGDICPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN50</accession>
    <name>G4MN50_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Spermidine/putrescine import ATP-binding protein potA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_05595</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
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    <dbReference type="STRING" id="242507.G4MN50"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_05595"/>
    <dbReference type="eggNOG" id="KOG0055">
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    <dbReference type="OMA" id="WYEMDGD"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
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        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
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        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
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    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
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            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="946"/>
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    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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            <end position="987"/>
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    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1047"/>
            <end position="1067"/>
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    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1073"/>
            <end position="1091"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
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            <end position="1207"/>
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    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="240"/>
            <end position="533"/>
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    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
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            <end position="1215"/>
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    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
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            <end position="1494"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
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    <feature type="region of interest" description="Disordered" evidence="9">
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN69</accession>
    <name>G4MN69_PYRO7</name>
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        <submittedName>
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        </submittedName>
    </protein>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
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    <dbReference type="KEGG" id="mgr:MGG_05611"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05611"/>
    <dbReference type="HOGENOM" id="CLU_190852_0_0_1"/>
    <dbReference type="InParanoid" id="G4MN69"/>
    <dbReference type="OMA" id="WEELIRP"/>
    <dbReference type="OrthoDB" id="5167280at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="80" mass="9566" checksum="207E0B7001645BB4" modified="2011-12-14" version="1">MCTYQYMDYSCGHRRTIVAEWCGRYRNTLQSHIRCRPEIPYYTRNDQICSHCHEQLNPRTVPWMPSREARGGSRSPPRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN96</accession>
    <name>G4MN96_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708831.1">
        <property type="nucleotide sequence ID" value="XM_003708783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN96"/>
    <dbReference type="GeneID" id="12985693"/>
    <dbReference type="KEGG" id="mgr:MGG_16027"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16027"/>
    <dbReference type="eggNOG" id="KOG1075">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046012_0_0_1"/>
    <dbReference type="InParanoid" id="G4MN96"/>
    <dbReference type="OrthoDB" id="4762718at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465290" evidence="2">
        <location>
            <begin position="17"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="413" mass="44641" checksum="EF3CFFDD1E12CD1C" modified="2011-12-14" version="1">MKSFGILSTFVFTAAAAPLAPRQEAIQTTNFSAATVQGGPGASIFALRAPVVMASPEVSNRRARPQSTPQALPQGQAESGHVSLDTRTANAPQPAGRGRYSSLPALAIKTLQQELENVETVGSWLEEVFAAKLESLQAPEDAALRRIVLEFDDVISGWFLSRTLPEKERSRSPSRSPTSSSERRSILITRTGTASSAFKGRGTPTNKSVTWAERAATPPAAAPTPILTPATRSYPIRTTPGNAPDSSATPSQSGRDRSQAPKRLTEQPSNRILIRVNDKLRMVTREPYAVTTKLAELVSVPHSEIPNAKRTPTGWGVTVASEETRQKLLNPSAVKAIMDALDAREVTVPTTWHTYAVSGVPRTLNCLDGRKDVHEVIQEEITVAAGQQPVNWHISKHGYDPYTAEGTWIVSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNY9</accession>
    <name>G4MNY9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709758.1">
        <property type="nucleotide sequence ID" value="XM_003709710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNY9"/>
    <dbReference type="SMR" id="G4MNY9"/>
    <dbReference type="GeneID" id="2685175"/>
    <dbReference type="KEGG" id="mgr:MGG_07002"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07002"/>
    <dbReference type="HOGENOM" id="CLU_2223759_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNY9"/>
    <dbReference type="OrthoDB" id="10533004at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="106" mass="11842" checksum="6755AC03F74EA36D" modified="2011-12-14" version="1">MARRKQHDLNCRSAGISWPTTSLTEVALKSQFDGERWPDSGGEADPATRGSDTQEEQNLQNRLTKDWDQVLLQSSGRDPQPVGDNWANSSQRRKTSNFLANADVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPG1</accession>
    <name>G4MPG1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710616.1">
        <property type="nucleotide sequence ID" value="XM_003710568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPG1"/>
    <dbReference type="GeneID" id="12986388"/>
    <dbReference type="KEGG" id="mgr:MGG_16450"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16450"/>
    <dbReference type="HOGENOM" id="CLU_2638527_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPG1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA58004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="77" mass="8716" checksum="4EF4A913994C73EA" modified="2011-12-14" version="1">MEGANGRLAWPRWLWDATRGNCSETSGSTLSRPPPFFSPHVALLQCAEVVMCSKSRFRSRGWLNRYRNMGWAGGSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPT9</accession>
    <name>G4MPT9_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709848.1">
        <property type="nucleotide sequence ID" value="XM_003709800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPT9"/>
    <dbReference type="GeneID" id="2680235"/>
    <dbReference type="KEGG" id="mgr:MGG_11761"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11761"/>
    <dbReference type="eggNOG" id="ENOG502QS87">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023635_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPT9"/>
    <dbReference type="OMA" id="GRSNSYH"/>
    <dbReference type="OrthoDB" id="4898142at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="618" mass="67711" checksum="D87D03B4820E0ACE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQC0</accession>
    <name>G4MQC0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Xylosidase/arabinosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_10621</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710718.1">
        <property type="nucleotide sequence ID" value="XM_003710670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQC0"/>
    <dbReference type="SMR" id="G4MQC0"/>
    <dbReference type="STRING" id="242507.G4MQC0"/>
    <dbReference type="GeneID" id="2682224"/>
    <dbReference type="KEGG" id="mgr:MGG_10621"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10621"/>
    <dbReference type="eggNOG" id="ENOG502SHWK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009397_11_2_1"/>
    <dbReference type="InParanoid" id="G4MQC0"/>
    <dbReference type="OMA" id="FNFNWWQ"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04084">
        <property type="entry name" value="CBM6_xylanase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18618">
        <property type="entry name" value="GH43_Xsa43E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005084">
        <property type="entry name" value="CBM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006584">
        <property type="entry name" value="Cellulose-bd_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052176">
        <property type="entry name" value="Glycosyl_Hydrlase_43_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772:SF2">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03422">
        <property type="entry name" value="CBM_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00606">
        <property type="entry name" value="CBD_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51175">
        <property type="entry name" value="CBM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465484" evidence="10">
        <location>
            <begin position="20"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="CBM6" evidence="12">
        <location>
            <begin position="320"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="11">
        <location>
            <begin position="476"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="447"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="7">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA58106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="511" mass="54041" checksum="E43A3A1F13D5A7BF" modified="2011-12-14" version="1">MMVPKMLPVLAAILACVRADNPFVQTLYSTDPAPMVYNGSIYVFTGHDEDGATTYNMRDWRLYSSKDVANWQDHGVVANLATFSWANANAWAPQTVARNGKFYLYVPIRRSTGAMAIGVAVADGIAGPYKDALGRPLVENNEIDPTVFIDDDGQAYLYWGNPNLSYVRLNADMISYSGGINRVSLTAAGFGQRSGNAQRPTTFEEGPWLYKRGGTYYMIYAANCCSEDVRYSTGPSATGPWTYRGVVMPAQGKSFTNHPGIVDFLGSSYFFYHNGALPGGGGYQRSVAVERFAYNADGTIPTIQMSAAGAPQVGTLNPYVRQEAETMAFSSGLGTEPCSEGGMALAYVNDGDYVKVKGVAFGAGARAFRARVASAGSGGRIELRLGGTSGTLVGSCAVGGTGGWQTWTTVSCAVSGATDTRDLFLRFAGSGSGNLFNVDWWQFDPASGTTPPETTAAGVPATTTRPPSATGSPPAQCAALYGQCGGEGWAGAKCCAQGACKVSNQWYSQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQG5</accession>
    <name>G4MQG5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetracenomycin polyketide synthesis O-methyltransferase tcmP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710763.1">
        <property type="nucleotide sequence ID" value="XM_003710715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQG5"/>
    <dbReference type="SMR" id="G4MQG5"/>
    <dbReference type="STRING" id="242507.G4MQG5"/>
    <dbReference type="GeneID" id="2678019"/>
    <dbReference type="KEGG" id="mgr:MGG_04787"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04787"/>
    <dbReference type="eggNOG" id="ENOG502RXVR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069348_2_0_1"/>
    <dbReference type="InParanoid" id="G4MQG5"/>
    <dbReference type="OMA" id="LQYHRYA"/>
    <dbReference type="OrthoDB" id="203237at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE YKTD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619:SF2">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="304" mass="34409" checksum="E85D9809269971AB" modified="2011-12-14" version="1">MATSTATEQGKGRVTLSGAQETLLLTLLARADDAESAHPILNDTLSAKIRKRIQEEHGYRFRERIPTPSKTFMAKLISARAKIFDEATEKFLRKNPGPATVLHLACGMDTRCHRVKWQGPGRVWIDVDKKDVVELRRAVVEDPDVPQGQGEYRLECPDIINDADWLRDIRVPNDRPVLIMFEGLVMYLNSEMVLGLFSKIMRHFEGNGKGGEIHFDSMGAAGYFILKIVGWNLVRNMGATFDFYMSNGQWLELHNPGLRQVNRESQAVALIRIVPYLWIFRVAVEVVDYLVGGTLLGGVYEFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQH8</accession>
    <name>G4MQH8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G-protein coupled receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_11962</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709080.1">
        <property type="nucleotide sequence ID" value="XM_003709032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQH8"/>
    <dbReference type="STRING" id="242507.G4MQH8"/>
    <dbReference type="GeneID" id="5049748"/>
    <dbReference type="KEGG" id="mgr:MGG_11962"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11962"/>
    <dbReference type="eggNOG" id="ENOG502QTGV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024810_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQH8"/>
    <dbReference type="OMA" id="LYAYYIP"/>
    <dbReference type="OrthoDB" id="18453at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="30"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="361"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="374"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA56468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="617" mass="67712" checksum="804B3EF2DDA564AF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQM4</accession>
    <name>G4MQM4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709923.1">
        <property type="nucleotide sequence ID" value="XM_003709875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQM4"/>
    <dbReference type="GeneID" id="12985296"/>
    <dbReference type="KEGG" id="mgr:MGG_16273"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16273"/>
    <dbReference type="HOGENOM" id="CLU_1886169_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQM4"/>
    <dbReference type="OrthoDB" id="10620363at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="135" mass="14833" checksum="3C9ED9C2ACC8AC63" modified="2011-12-14" version="1">MDEQVFRADSLSGNTYEIDTEAHVQGETEGLQSVEVNEPCCATVRMMVAKLKGKNPKRQHWHREKYIVVVIAGGEAKAGAWTEVETDTFQGPCQRLQAKSPVIHQAITCTRITASCSPVQRSILPLGTLLQSHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR73</accession>
    <name>G4MR73_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710017.1">
        <property type="nucleotide sequence ID" value="XM_003709969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR73"/>
    <dbReference type="GeneID" id="12985317"/>
    <dbReference type="KEGG" id="mgr:MGG_16293"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16293"/>
    <dbReference type="InParanoid" id="G4MR73"/>
    <dbReference type="OrthoDB" id="10623449at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="184" mass="20747" checksum="763DEA440C846FC3" modified="2011-12-14" version="1" fragment="single">SKSHSIRTLDRLHSSRLRESRLVDGWAEGVRASDSPIATARRCPWCSSGTVSTARSRSTTSSGNNEAVRDFCRRHISSEAGKCARLNETNIPQERCDVKQMEYRRRNYENCHGTVLKRFWLAAPSHVQSHPREVIPVERDNFCLHMFTANSIPLIHHQEECGSNHCPAWQGPAPGCEKRQPGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRH0</accession>
    <name>G4MRH0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cupin 2 conserved barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709209.1">
        <property type="nucleotide sequence ID" value="XM_003709161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRH0"/>
    <dbReference type="SMR" id="G4MRH0"/>
    <dbReference type="STRING" id="242507.G4MRH0"/>
    <dbReference type="GeneID" id="12984405"/>
    <dbReference type="KEGG" id="mgr:MGG_16125"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16125"/>
    <dbReference type="eggNOG" id="ENOG502S6HE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062260_1_0_1"/>
    <dbReference type="InParanoid" id="G4MRH0"/>
    <dbReference type="OMA" id="CMIVSAD"/>
    <dbReference type="OrthoDB" id="3223416at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466044" description="Cupin 2 conserved barrel domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="20829" checksum="8DBF32DE68F5431B" modified="2011-12-14" version="1">MLPQVSSRTLLLIPILLHQAVTVVNAQGTSNMPPLNVTAISASGGDSTFECWQFGPFTSVTAPGVNDASALLLTTAATQVNYAMFPAGSTGGLHRSPRLQFVVFMTGRARITLPNGNGTYEINGGGRGCMIVSADTSDVSRVGHTTDYPGDTPTGVMQVPITNGRQGLGRYRVLHQGTCTEEELGGTITTPNDGGGYIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRR9</accession>
    <name>G4MRR9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_13798</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710896.1">
        <property type="nucleotide sequence ID" value="XM_003710848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRR9"/>
    <dbReference type="GeneID" id="2677982"/>
    <dbReference type="KEGG" id="mgr:MGG_13798"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13798"/>
    <dbReference type="eggNOG" id="KOG1286">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024512_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRR9"/>
    <dbReference type="OMA" id="QNEAWAC"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43495">
        <property type="entry name" value="GABA PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43495:SF5">
        <property type="entry name" value="GAMMA-AMINOBUTYRIC ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="86"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA58284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="304" mass="33165" checksum="D01B92D691C6653B" modified="2011-12-14" version="1">MGLLYAVITFGIVAICVGETIGQLVQLFPTRNAIFQYIHTFVDHDVAWATGILYWLTYSAIIPFQVLTASRLLEFWFYEVLYYNSYVLPIVAFGYEGFESLAMAAFEAKNSGKTKMLIPLWIHGTIPVAYFFLTLGSILTVDWQDPHLPSSYGSDTDNGPAQVKKRHGDCNGHTPNSVVILGIFKGVTTFGQNEAWACFGRGAINAAGVLNGILIFTTMSAASAALYVSSRTLYGLTYKEKVGGRFGKFLQESTGTVWKETGAPAKAVVASVFALYVIIGLSYVARQGSKSTADDLPTQRKIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MST6</accession>
    <name>G4MST6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713597.1">
        <property type="nucleotide sequence ID" value="XM_003713549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MST6"/>
    <dbReference type="STRING" id="242507.G4MST6"/>
    <dbReference type="GeneID" id="2677931"/>
    <dbReference type="KEGG" id="mgr:MGG_04568"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04568"/>
    <dbReference type="eggNOG" id="ENOG502R9DY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041437_0_1_1"/>
    <dbReference type="InParanoid" id="G4MST6"/>
    <dbReference type="OMA" id="LFGFREC"/>
    <dbReference type="OrthoDB" id="1022638at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="44743" checksum="9EA0BE838C3FB3C4" modified="2011-12-14" version="1">MPHRKSTSEPTGSLGTDMVRVLVGPHKKSFDIHKKLLCSTSSFFRESLAAIPDGLTGSADSKTTVLWFSAESPEMFDLFVLWLYHRQTFSSAVDRALSAIVAAEADTGDHEAGSARLRGLRWALVHLHLFAAAVDLPALQDASMDAIQDLYLRLDWDVSPRFVRSLYERRAAEAFRLRKWAVAMVAWTLSSGGSSGRCNGDDDDANDLVYQEDRDAAAEAIASQFQHLMDRFREFHDDYTAHLRKMAGSRSSVCIKNPQLRIPTNCLRNDERNFGFRMCSFHSHRASVGQGQCPHVKGDESSRHSVMVMPISSSPSPRSHMRSFSHDTNSGASVSSDCTTPPPHDDEEKPTLGVAMTATRHRSRSDLGFKPVRLSSARFSSARLQSTLPTIPPTPNDPATTSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSU3</accession>
    <name>G4MSU3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7603 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_04575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003713556.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MSU3"/>
    <dbReference type="SMR" id="G4MSU3"/>
    <dbReference type="STRING" id="242507.G4MSU3"/>
    <dbReference type="GeneID" id="2677971"/>
    <dbReference type="KEGG" id="mgr:MGG_04575"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04575"/>
    <dbReference type="eggNOG" id="ENOG502QU2M">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_002590_1_0_1"/>
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    <dbReference type="OMA" id="DQKWQCE"/>
    <dbReference type="OrthoDB" id="5395440at2759"/>
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        <property type="component" value="Chromosome 2"/>
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    <dbReference type="InterPro" id="IPR056023">
        <property type="entry name" value="DUF7603"/>
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    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR23159:SF60">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24554">
        <property type="entry name" value="DUF7603"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7603" evidence="3">
        <location>
            <begin position="895"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="244"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="315"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="481"/>
            <end position="528"/>
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    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="561"/>
            <end position="581"/>
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    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="680"/>
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    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="1041"/>
            <end position="1113"/>
        </location>
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        <location>
            <begin position="731"/>
            <end position="849"/>
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    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="934"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="83"/>
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        <location>
            <begin position="245"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="318"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="496"/>
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    </feature>
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        <location>
            <begin position="509"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="684"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1059"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1083"/>
            <end position="1098"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1191" mass="131907" checksum="7CEA8314A85E577D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT77</accession>
    <name>G4MT77_PYRO7</name>
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        <recommendedName>
            <fullName evidence="7">Phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="7">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
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        <name evidence="10" type="ORF">MGG_07151</name>
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    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Vacuole membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PI3/PI4-kinase family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003715301.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MT77"/>
    <dbReference type="SMR" id="G4MT77"/>
    <dbReference type="FunCoup" id="G4MT77">
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    <dbReference type="STRING" id="242507.G4MT77"/>
    <dbReference type="GeneID" id="2683273"/>
    <dbReference type="KEGG" id="mgr:MGG_07151"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07151"/>
    <dbReference type="eggNOG" id="KOG2381">
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    <dbReference type="HOGENOM" id="CLU_009049_2_0_1"/>
    <dbReference type="InParanoid" id="G4MT77"/>
    <dbReference type="OMA" id="NWMVKVD"/>
    <dbReference type="OrthoDB" id="3349449at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
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    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
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        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="180"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="336"/>
            <end position="385"/>
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            <begin position="431"/>
            <end position="490"/>
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    </feature>
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            <end position="750"/>
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        <location>
            <begin position="1"/>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
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            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
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            <begin position="439"/>
            <end position="463"/>
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    </feature>
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        <location>
            <begin position="475"/>
            <end position="487"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
            <dbReference type="RuleBase" id="RU367084"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="841" mass="92699" checksum="051954BCD9B2CBA0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUA5</accession>
    <name>G4MUA5_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">DUF1295 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_10154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713793.1">
        <property type="nucleotide sequence ID" value="XM_003713745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUA5"/>
    <dbReference type="GeneID" id="2681781"/>
    <dbReference type="KEGG" id="mgr:MGG_10154"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10154"/>
    <dbReference type="eggNOG" id="KOG4650">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043418_0_1_1"/>
    <dbReference type="InParanoid" id="G4MUA5"/>
    <dbReference type="OMA" id="WRKGGYQ"/>
    <dbReference type="OrthoDB" id="201504at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
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    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF23">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="40946" checksum="9B35317A79C6B4BB" modified="2011-12-14" version="1">MALPALNALEECSDFSKTVEPFLPQLYELPNKLAEVFTSGGSLRALYLGTNPLISAFAFSLVLGFVFLVVSEINKNYSQVDRCWSLLPTVYLAHFDVWARMAGLPSERLDTALFFSTVWSIRLTYNYARKGGYNVGSEDYRWEIVRKNAPAWAFHLLNVVFISFIQSILLFLIAAPAYPMLLAIQFEPQASTADYVFMSIQLGLVALEWFADQQQWDFHGAKKQYQESAKVPQGYTHAEVEQGFVSSGLWAYSRHPNFAAEQTIWFLLYQWSCYDTKVLYSWAAVGSVSLLSLFQGSTWLTELITSGKYPDYKDYQKQVGMFGTYRTGLPGKGYFQETQDHQDKRACQEEREEEAQVNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUM2</accession>
    <name>G4MUM2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713802.1">
        <property type="nucleotide sequence ID" value="XM_003713754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUM2"/>
    <dbReference type="STRING" id="242507.G4MUM2"/>
    <dbReference type="GeneID" id="2681790"/>
    <dbReference type="KEGG" id="mgr:MGG_10163"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10163"/>
    <dbReference type="eggNOG" id="ENOG502RZT9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042059_1_1_1"/>
    <dbReference type="InParanoid" id="G4MUM2"/>
    <dbReference type="OMA" id="YLLTTFY"/>
    <dbReference type="OrthoDB" id="5394254at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="341" mass="36545" checksum="87D1B5778820E451" modified="2011-12-14" version="1">MSSPIRVPTAAVESSDPTGDLVSGKDARLMLESTTRQKTSRLPSALRFPLVVVLSLAWTAVGYGSIAQWISEQLFSFSRSLSRTQGASLLIWRVLELGIGWFGNYDSYDLAAVSVLSHGPTLYLLSTFYGMRPLAAATCLSIDVLSSVVPFALLRPLSAAHLAAPNVPNRILLVDRPIQAYTALMVSAVYALTLSFAYGPFLRSILLLNFTGIPSIEPSKTLEATIWTIALSLAFGVAARTFIFVPAAATGRVVEDDMLEKFDPVSATLGETLLFNAWGFTAQTKTVILRTLVVMFISGGRTFMQCGLTIAGVEFAGAAMYSLVWAVASLFAGLGLGLIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUN3</accession>
    <name>G4MUN3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">60S ribosomal protein L23a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_10185</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713813.1">
        <property type="nucleotide sequence ID" value="XM_003713765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUN3"/>
    <dbReference type="SMR" id="G4MUN3"/>
    <dbReference type="FunCoup" id="G4MUN3">
        <property type="interactions" value="758"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUN3"/>
    <dbReference type="GeneID" id="2681812"/>
    <dbReference type="KEGG" id="mgr:MGG_10185"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10185"/>
    <dbReference type="eggNOG" id="KOG1751">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037562_0_1_1"/>
    <dbReference type="InParanoid" id="G4MUN3"/>
    <dbReference type="OMA" id="RLDHHKV"/>
    <dbReference type="OrthoDB" id="1267328at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000035">
        <property type="entry name" value="60S ribosomal protein L23a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_A">
        <property type="entry name" value="Ribosomal_uL23_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_uL23_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005633">
        <property type="entry name" value="Ribosomal_uL23_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011118">
        <property type="entry name" value="PRK14548.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L23A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03939">
        <property type="entry name" value="Ribosomal_L23eN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL23 N-terminal" evidence="8">
        <location>
            <begin position="18"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA54006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="157" mass="17383" checksum="FE888AEFC10163B8" modified="2011-12-14" version="1">MAPKDAKKGGASKAPKGSKQAQAASKAALKGVHAHKRVKARYTTSFHRPKTLQLSRAPKYPRKSVPHLPRLDEHKIIVHPLNTESAMKKIEENNTLVFIVDIKANKAQIKQALKKLYDLDVLKINTLIRPDGQKKAYVRLTPDVDALDIAATKLALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUT3</accession>
    <name>G4MUT3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Synaptobrevin homolog YKT6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_01681</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714670.1">
        <property type="nucleotide sequence ID" value="XM_003714622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUT3"/>
    <dbReference type="SMR" id="G4MUT3"/>
    <dbReference type="STRING" id="242507.G4MUT3"/>
    <dbReference type="GeneID" id="2679358"/>
    <dbReference type="KEGG" id="mgr:MGG_01681"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01681"/>
    <dbReference type="eggNOG" id="KOG0859">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064620_1_1_1"/>
    <dbReference type="InParanoid" id="G4MUT3"/>
    <dbReference type="OMA" id="NTKLMIM"/>
    <dbReference type="OrthoDB" id="190375at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.50:FF:000017">
        <property type="entry name" value="Synaptobrevin-like protein Sybl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000004">
        <property type="entry name" value="Vesicle-associated membrane protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051097">
        <property type="entry name" value="Synaptobrevin-like_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136">
        <property type="entry name" value="SNARE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136:SF168">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="11">
        <location>
            <begin position="11"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="151"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA54863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="237" mass="26109" checksum="8F92BEAFFE21CBA4" modified="2011-12-14" version="1">MASSSTPPTPLLYSCIAHNSTILTECTTSASSQTSSLASLVLPKITHTSPQKLTYTHGAHHIHYIAEAPSDHGPHAASAGGLTFLVIADSSVGRSVPFGYLFEIRRRFLEEYPPGSTDFADQPNYGAASFNGELRRLMVEIGSTRQGRDDAVQNAQREIDDVRGIMTRNIEGLLERGERIDLLVDKTDRLGGSAREFRVRSRGLKRQMWWKNVKLMGLLGLVMFLILLTIIIAVKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVA5</accession>
    <name>G4MVA5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714734.1">
        <property type="nucleotide sequence ID" value="XM_003714686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVA5"/>
    <dbReference type="GeneID" id="2679755"/>
    <dbReference type="KEGG" id="mgr:MGG_11156"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11156"/>
    <dbReference type="HOGENOM" id="CLU_1555578_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVA5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="172" mass="19220" checksum="7ED769C416F6C5F1" modified="2011-12-14" version="1">MNIRICITCGFKITQYLRKYKCMYWSLFRTWVMVVGAFPPLAPRSKQQQTDTANSRITEIESPSQGQPWAPMANAAAHEADRSFRSSQARGDRPPGDFRVPDYSDDRRHGLSSSRPYRVDWGEMDGPIFDLMVPRPLRVITKGASVAQVPGTLCLVGINPRGVSDGISPMTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVW4</accession>
    <name>G4MVW4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_15093</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715639.1">
        <property type="nucleotide sequence ID" value="XM_003715591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVW4"/>
    <dbReference type="STRING" id="242507.G4MVW4"/>
    <dbReference type="GeneID" id="12986727"/>
    <dbReference type="KEGG" id="mgr:MGG_15093"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15093"/>
    <dbReference type="eggNOG" id="ENOG502RZAE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032324_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVW4"/>
    <dbReference type="OMA" id="GLAMTRC"/>
    <dbReference type="OrthoDB" id="1621678at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052202">
        <property type="entry name" value="Yeast_MetPath_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782:SF14">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47782">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="70"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="605" mass="66688" checksum="0E3AE01B7DD77F34" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWG7</accession>
    <name>G4MWG7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Catechol 1,2-dioxygenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_08983</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714022.1">
        <property type="nucleotide sequence ID" value="XM_003713974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWG7"/>
    <dbReference type="SMR" id="G4MWG7"/>
    <dbReference type="STRING" id="242507.G4MWG7"/>
    <dbReference type="GeneID" id="2679968"/>
    <dbReference type="KEGG" id="mgr:MGG_08983"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08983"/>
    <dbReference type="eggNOG" id="ENOG502SMA8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046727_1_1_1"/>
    <dbReference type="InParanoid" id="G4MWG7"/>
    <dbReference type="OMA" id="VWHANLM"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF5">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASE PRCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="8">
        <location>
            <begin position="35"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="7">
        <location>
            <begin position="118"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA54215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="319" mass="36154" checksum="B026E443D48995D9" modified="2011-12-14" version="1">MASENTNGATKPAESKFDPNFTQHVIDLMSPETLPRHREILTSLIRHMHDFCREVELKQDEWVLGVNYINSLGQAYKKNRNETWRLMDILGIESLVDEINNKVVTPDGKAPTSSAILGPFWSPETPFRDLGASCVQDMPADGQLTRFHGVIRDVETGKGIPGAVFDMWQASTNGKYDVFDPENQTRHNLRGKFKTDEEGRFWFYCLKPTEYAIDTTGPSAVLLKMMHRHPYRPAHIHMMVTHPDYLGITAQLYPRDDPYLETDTVSAVKPDLLLDFNPAAKDDPMGAQLDCEYNVNMVSKKYKPDSTMLLGNANQGNFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWK9</accession>
    <name>G4MWK9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-hydroxyacyl-CoA dehydrogenase type-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714064.1">
        <property type="nucleotide sequence ID" value="XM_003714016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWK9"/>
    <dbReference type="SMR" id="G4MWK9"/>
    <dbReference type="STRING" id="242507.G4MWK9"/>
    <dbReference type="GeneID" id="2679281"/>
    <dbReference type="KEGG" id="mgr:MGG_01180"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01180"/>
    <dbReference type="eggNOG" id="KOG1199">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_42_0_1"/>
    <dbReference type="InParanoid" id="G4MWK9"/>
    <dbReference type="OMA" id="RHIFEND"/>
    <dbReference type="OrthoDB" id="3819888at2759"/>
    <dbReference type="PHI-base" id="PHI:8929"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658:SF8">
        <property type="entry name" value="17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="263" mass="27034" checksum="8CD8ECEAFDE7322E" modified="2011-12-14" version="1">MKISGRTFVISGGASGLGRACAVDLVAHGANVAVLDINPELGDSLVKELGAEKARFFTVDVTDSGSIGKAVEGSASWAKETGKPFGGVIPAAGVGFPGLILDSKKNPLSLDSFDLVVAINLRGTIDLVRQCLPHIAAAAADGPDGEHGVVIMISSSAAFDGQMGQTAYAASKGALASAALPMARDLSRHGIRVAVIAPGMFETAMTAAMSDKVRNGLEKTLEFPKRGGKPDEFAGLVRHIIENSMLNGVVVRLDGAARMPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWM5</accession>
    <name>G4MWM5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714887.1">
        <property type="nucleotide sequence ID" value="XM_003714839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWM5"/>
    <dbReference type="GeneID" id="2679256"/>
    <dbReference type="KEGG" id="mgr:MGG_01866"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01866"/>
    <dbReference type="eggNOG" id="ENOG502SPEF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042066_1_0_1"/>
    <dbReference type="InParanoid" id="G4MWM5"/>
    <dbReference type="OMA" id="SHYRGRW"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="53896" checksum="755FEF1BDF666850" modified="2011-12-14" version="1">MFSSPEPIFRTTSPQLNIQLDTGDKHSFSPGDTIIGRVVRQAPIVAPHGSIRLSLHGRSLVRVDESSGGKDKTYTGEVRLLQGGRHTRVLFEGPLHVAEGPGGVAQSWAFAVDVPTHVELERPDLGLGGNQHSFVPVPPDCTTGRYALPQTFSRTGGRSSARIEYYLEAVLQYRTHGGSSGRTVAATLPVGIRTPNHAPPIADLRPVKRRRLAFVQSFRLLPGMDGPSARLSLLQRAQSAVGSRRVPMLWGQWELTSPTVVQPGNPTPLPICVRFIPDARRSSPAVRGSPAPTVRLLSLVLRVQSLAVVQCRGGWADGAPRRQTCARASECASIWPPRGAGLPGRHLLGRKEWRAVCERQAPVYVPCADEWPALEVGAEAGFSLGGGGQGAGRLLLPLLTPTFATFNVRQHYRFEYEIEALVAGEEVKIPISEVVTVLPPSEDGPGGAPQVATPGNAQGEWTPSPLEGRSESWIRPPCESGAPPSFDEAVSGAGGQQMASIHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXJ3</accession>
    <name>G4MXJ3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714131.1">
        <property type="nucleotide sequence ID" value="XM_003714083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXJ3"/>
    <dbReference type="STRING" id="242507.G4MXJ3"/>
    <dbReference type="GeneID" id="2679431"/>
    <dbReference type="KEGG" id="mgr:MGG_01229"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01229"/>
    <dbReference type="eggNOG" id="ENOG502SI2P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065434_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXJ3"/>
    <dbReference type="OMA" id="IASHNLY"/>
    <dbReference type="OrthoDB" id="5352400at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="269" mass="30525" checksum="E131C8E205B00319" modified="2011-12-14" version="1">MAIKGYTVLRRKWKSRKPIWALMLAELITMIPLLVLFGIAQPDTFRTLMWRIGYAEKLNSNPNIILYALANHEPIPKLPFVWSQLLTEFNVAISVMSLFFLLAKMIGFIMKIYFPVIAVGCNIVMTAVYAVSVYGQAGPDYLDPRYPSPTPWYLRRSCDVAEGYGAGKTCMIIQGTFAATVVMLCIYVINLGWSIFNMIPTKHDKTHDEDEDGEEYASSDSPTEVKTWEMQPQTAGPGGVPFTPRTQAFHTLDRKLPFRAYAEQRQQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY07</accession>
    <name>G4MY07_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">D-serine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-serine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_15402</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the conversion of D-serine to pyruvate and ammonia. May play a role in D-serine detoxification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13977"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="EC" id="4.3.1.18"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:13978"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DSD1 family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.18" evidence="11"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713342.1">
        <property type="nucleotide sequence ID" value="XM_003713294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY07"/>
    <dbReference type="SMR" id="G4MY07"/>
    <dbReference type="FunCoup" id="G4MY07">
        <property type="interactions" value="32"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MY07"/>
    <dbReference type="GeneID" id="12986221"/>
    <dbReference type="KEGG" id="mgr:MGG_15402"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15402"/>
    <dbReference type="eggNOG" id="ENOG502QRZ0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031639_0_0_1"/>
    <dbReference type="InParanoid" id="G4MY07"/>
    <dbReference type="OMA" id="EIRPGNF"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036088">
        <property type="term" value="P:D-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000016">
        <property type="entry name" value="D-serine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0216">Detoxification</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="14">
        <location>
            <begin position="440"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00066349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00075219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA53535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="584" mass="61917" checksum="2F4B9D32C31263C0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYP5</accession>
    <name>G4MYP5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714277.1">
        <property type="nucleotide sequence ID" value="XM_003714229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYP5"/>
    <dbReference type="GeneID" id="12984628"/>
    <dbReference type="KEGG" id="mgr:MGG_15676"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15676"/>
    <dbReference type="HOGENOM" id="CLU_1042338_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYP5"/>
    <dbReference type="OrthoDB" id="10589734at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="267" mass="29788" checksum="174167513F984594" modified="2011-12-14" version="1">MNQARSGTLSRVGQRLVPYEEKGWSTKSGKWVLLSSPSLRGRERAKPYVESPEQPRPLPSEGSTILVKVETSDEREPEEVGNDKSGFGGGQADRDDGKRRNKKKTNLYLKITSRQEAGFPQKSSRDAAKLQSWTGGKTTPAGDQEKDGDEFELFLCTLWQVCAVGRCPRIGPKRSLTLHSGFQALLGKEISGDRLPLITTLRVPGLFPSLPRPRRYLLNSSRIPHYHHHRRVAPGGGGGVVFDARIYYRMDLLSSTSRDYPISAWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYS4</accession>
    <name>G4MYS4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715110.1">
        <property type="nucleotide sequence ID" value="XM_003715062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYS4"/>
    <dbReference type="GeneID" id="12985556"/>
    <dbReference type="KEGG" id="mgr:MGG_15824"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15824"/>
    <dbReference type="eggNOG" id="ENOG502T3XQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174965_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYS4"/>
    <dbReference type="OMA" id="FGNSHCL"/>
    <dbReference type="OrthoDB" id="5207001at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465704" description="Secreted protein" evidence="1">
        <location>
            <begin position="35"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="11895" checksum="C97BC4BDB19C92ED" modified="2011-12-14" version="1">MFSAQHTSIAMAATQGGLLLLAMLLVLVPSTAFAYPTTTSYMWPHVCQPTRFDEFLAVSRSTGKPVSLGPKGFYIHFGNSHCLFLRAETPGQEDKYTYYQQALVAGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYS9</accession>
    <name>G4MYS9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715115.1">
        <property type="nucleotide sequence ID" value="XM_003715067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYS9"/>
    <dbReference type="GeneID" id="12985561"/>
    <dbReference type="KEGG" id="mgr:MGG_15827"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15827"/>
    <dbReference type="HOGENOM" id="CLU_2622482_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYS9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="78" mass="8035" checksum="C82F2F58884EDAB5" modified="2011-12-14" version="1">MACATNAIHMVDSGHNQRHRRSTLKCSFSAQAAILSPNAPLASGPDPGGTSCTGGEPPNLLREQINTAGKGGKENMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ55</accession>
    <name>G4MZ55_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714329.1">
        <property type="nucleotide sequence ID" value="XM_003714281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ55"/>
    <dbReference type="SMR" id="G4MZ55"/>
    <dbReference type="STRING" id="242507.G4MZ55"/>
    <dbReference type="GeneID" id="2679128"/>
    <dbReference type="KEGG" id="mgr:MGG_01386"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01386"/>
    <dbReference type="eggNOG" id="ENOG502SIRW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022730_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ55"/>
    <dbReference type="OMA" id="EPLQWCA"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF284">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="43"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="472" mass="51260" checksum="E0173582A2E3A42F" modified="2011-12-14" version="1">MGGGNNPPGFPHSNPTVSYWQDPPHKIANHRSTETIPDQTWEYVIVGSGVSGAATAFKLLSRDPSLKVVMLEARTAASGASGRNGGHCRPGWWSHFQLYATAFGVDEALKFEALEEGTVQDIADFVREHEVDNDFQDLETADIFVTAEGWEEAMAKLEFREEVRRKTAGDRGSQVKKTVLHKEEARRRLGMPDAQGAIVYPAHAQNPYLLVCRMLELAMEKGLNLQTNTPALAVKQDDGGVWTVDTDRGTVRARNVVLATNAYSNSLHAGLAGTKFLIPARSQVAALRPGKSMDPNFLFGHSGGPCDVPTGDYFMTAPRGSRGEGDVLWGGGRSVSETSEVGITDDSTVNEHVASYLHRAPGIFYGADKWGRDGDGEGGDGVVRDWTGITCYTPDTLPLVGAAPGEPGLWMTIGMNGHGMAMAFRCAEALVQTMLSGKGADMPDWFPKCMRLERAWEKPKLNVRTAWFAECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ72</accession>
    <name>G4MZ72_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SIS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715152.1">
        <property type="nucleotide sequence ID" value="XM_003715104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ72"/>
    <dbReference type="SMR" id="G4MZ72"/>
    <dbReference type="FunCoup" id="G4MZ72">
        <property type="interactions" value="433"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZ72"/>
    <dbReference type="GeneID" id="2678416"/>
    <dbReference type="KEGG" id="mgr:MGG_08180"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08180"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017633_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ72"/>
    <dbReference type="OMA" id="MPIRKEG"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006413">
        <property type="term" value="P:translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000136">
        <property type="entry name" value="DnaJ domain-containing protein Psi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000013">
        <property type="entry name" value="DnaJ subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="159"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA55345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="371" mass="40315" checksum="05BD67E1EE08829A" modified="2011-12-14" version="1">MVKETKLYDALGIKPDATQDDIKKGYRKQALKWHPDKNKNNTDAAEKFKEVSQAYEILSDPEKRKTYDQYGLEFLLRGGVPMDTDGGNPFAGGAGGMPGGFQNFGFGGPGGGGTFRFSTNGSGFSFSNPDSVFSDFFRQASGGGGGGMGGINPEDLEDILGGGARSSRGGPRVRSSFGDSVPGGGARSQRQPTPEITTVERPLPVTLEEMFNGTTKKMKIKRKMFDDSGKRTTTDTVLEVPIKPGLKKGSKIRFKGVGDQEEGGQQDLVFIVEEKKHALYTREGDDVVHDVDLELKEALTGWKRTITTIDGKQLQIDKAGPTQPGSRDTYPGLGMPISKKPGQRGNFVVKYNVKFPTYLTPEQKTKLKEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZI1</accession>
    <name>G4MZI1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BNR/Asp-box repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714347.1">
        <property type="nucleotide sequence ID" value="XM_003714299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZI1"/>
    <dbReference type="SMR" id="G4MZI1"/>
    <dbReference type="STRING" id="242507.G4MZI1"/>
    <dbReference type="CAZy" id="GH93">
        <property type="family name" value="Glycoside Hydrolase Family 93"/>
    </dbReference>
    <dbReference type="GeneID" id="2679229"/>
    <dbReference type="KEGG" id="mgr:MGG_01402"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01402"/>
    <dbReference type="eggNOG" id="ENOG502QW46">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036301_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZI1"/>
    <dbReference type="OMA" id="YVMADSP"/>
    <dbReference type="OrthoDB" id="2130735at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd15482">
        <property type="entry name" value="Sialidase_non-viral"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792">
        <property type="entry name" value="BNR/ASP-BOX REPEAT DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38792:SF1">
        <property type="entry name" value="BNR_ASP-BOX REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="Sialidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465845" evidence="2">
        <location>
            <begin position="20"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="399" mass="43887" checksum="D4D9CCE9DB90EAA8" modified="2011-12-14" version="1">MRLNLVKAGLLSASTLVAAQNESPELEPFSLFDNRVIYKAREGESLSYPRHVELESGELLVTASLRTNLTSPTYFPVFESEDGGVSWEWVSNITDQVNGWGMSAQPALMELTEPIGDYSAGTILASGNSWSQNGTRIDVYASLDKGRSWEFVSRVTQGGRPNTTNGADPVWEPFLMLYDHQIVCYYSDQRDPLHGQKLAHQTSPDLKTWGPVINDVAYDLYIARPGMTVVAKIETMDKYIVVYEYPIGNSSSHGANYPVHYRIASDPLLFDSAEDHPIVIGGNFAPNASPYVVWSPVGGPNGTIIVSDADYDEVYTNRFGGDPDKWVKNYSPQPGAYSRALHVFQNKTDHLMILGGSKFEGGPPDLTLSVVSITEMHANSTEGEPGPGCPAQKSKRRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0B6</accession>
    <name>G4N0B6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_15193</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711261.1">
        <property type="nucleotide sequence ID" value="XM_003711213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0B6"/>
    <dbReference type="GeneID" id="12986994"/>
    <dbReference type="KEGG" id="mgr:MGG_15193"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15193"/>
    <dbReference type="eggNOG" id="ENOG502RDNH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033465_0_1_1"/>
    <dbReference type="InParanoid" id="G4N0B6"/>
    <dbReference type="OMA" id="HEWFFYV"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF13">
        <property type="entry name" value="RTA1 DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA51454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="275" mass="30317" checksum="15AB7A34A757CE00" modified="2011-12-14" version="1">MSEGNQAPESLLFYVSMQGRLLSSRQPVPELGLHGLASAFNLVIHSGFAVRIFCSFNYRHANAFIASLFIIYATVRLKAAEYVAQGHALMKASLILLLLFAVIFVSLAGSVHHRCLKRGIRNRKVTIPLTTLYFSMGFITARTIFRTGENFAFENLTGTVSSGSQALDPPPVVLCERYFYVFEATFMFLAVAVSNLFHPGQFLPSKNKIYLAQDGQTELEVPGWSDKRPFIVTLCDPFNLAGCLDRKPGADGTNFWEDNGFGFPLEANKGGGLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N170</accession>
    <name>G4N170_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_07458</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711356.1">
        <property type="nucleotide sequence ID" value="XM_003711308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N170"/>
    <dbReference type="SMR" id="G4N170"/>
    <dbReference type="STRING" id="242507.G4N170"/>
    <dbReference type="GeneID" id="2683378"/>
    <dbReference type="KEGG" id="mgr:MGG_07458"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07458"/>
    <dbReference type="eggNOG" id="ENOG502S4AX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012074_0_1_1"/>
    <dbReference type="InParanoid" id="G4N170"/>
    <dbReference type="OMA" id="FHMCDTG"/>
    <dbReference type="OrthoDB" id="3431704at2759"/>
    <dbReference type="PHI-base" id="PHI:5682"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF28">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA51549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="875" mass="96311" checksum="4F9F9CE07E788919" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N197</accession>
    <name>G4N197_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase accessory subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_07477</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711383.1">
        <property type="nucleotide sequence ID" value="XM_003711335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N197"/>
    <dbReference type="SMR" id="G4N197"/>
    <dbReference type="STRING" id="242507.G4N197"/>
    <dbReference type="GeneID" id="2683397"/>
    <dbReference type="KEGG" id="mgr:MGG_07477"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07477"/>
    <dbReference type="eggNOG" id="KOG3909">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037350_1_0_1"/>
    <dbReference type="InParanoid" id="G4N197"/>
    <dbReference type="OMA" id="VPHIAHD"/>
    <dbReference type="OrthoDB" id="27601at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03043">
        <property type="entry name" value="QTRT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028592">
        <property type="entry name" value="QTRTD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="7">
        <location>
            <begin position="30"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="421"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA51576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="476" mass="51320" checksum="CF46EA11BEC54929" modified="2011-12-14" version="1">MEYSETGKLPDSDPAMELFTLLRASTPGTGARLGRLSLPGRNPVDTPNFFSGTSRGVVPHLTPDNLRRHADMVRGAYMAFEDFIERNQRDPTRVAPLLQTTDKMKTVRAPLHAFTALPDPIPTVLGARRMPPAACSLGNMADSVSVFTSTGVQTLTTAQYADAIVNLRPDVVIPMADLTFTTGTPSSKRAVRMADRTEDWMIKLRKQLDGGSKSNETAIFAPTLPIPHPIQWEYLRCLNEDMVGFIKGLAVYDIDILPDLAGYDNLNQLPRLSLDLPSTPHQILRQISLGADVILLPFINAFSEAGVAFTFTLPTSQNPSPPAKPSTLLPLGVDLSSPTYNTSLSPLSDGCTCPACTSHHRAYVHHLLSAREMLAWTLLQVHNHHVVASLFAAARASLVAGTFEADAERFAASYEADLPIGGGERPRARGYNNGKGRGPGEAPPPRLNRPAWGKLGEVNSVQAAAAAAVPAPMDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3H4</accession>
    <name>G4N3H4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712456.1">
        <property type="nucleotide sequence ID" value="XM_003712408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3H4"/>
    <dbReference type="SMR" id="G4N3H4"/>
    <dbReference type="GeneID" id="2675535"/>
    <dbReference type="KEGG" id="mgr:MGG_04960"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04960"/>
    <dbReference type="eggNOG" id="KOG4754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039184_1_0_1"/>
    <dbReference type="InParanoid" id="G4N3H4"/>
    <dbReference type="OMA" id="HDKITHL"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF54">
        <property type="entry name" value="PHOSPHATASE SPAC5H10.03-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="253" mass="28102" checksum="E95B2BCE3B46332B" modified="2011-12-14" version="1">MPATIYFVRHAQGYHNLPKVPGGPNPSLLADPDLTELGKEQCAELSKNFPFHDKITHLVASPLRRTLYTCLLSFGPVLEQGRVQKVTALPELQEIAALPSDTGSDPAVLAKEFGGEKVDLGLVKDDWTDKGPGSPFAPELEKLDARARAARIWLRKLASEVEGDEAHIVVVTHGAILHFLTEDWDGTSIYNSTGWQNTEWRSYEFSDSSGQDSQASLKETKQSWERRRGTAIPLTETEQRELKAVLWRGVKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4E4</accession>
    <name>G4N4E4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Nucleoporin Nup157/170</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_05095</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Nucleoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the non-repetitive/WGA-negative nucleoporin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712619.1">
        <property type="nucleotide sequence ID" value="XM_003712571.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N4E4"/>
    <dbReference type="FunCoup" id="G4N4E4">
        <property type="interactions" value="1208"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N4E4"/>
    <dbReference type="GeneID" id="2675554"/>
    <dbReference type="KEGG" id="mgr:MGG_05095"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05095"/>
    <dbReference type="eggNOG" id="KOG1900">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000429_0_1_1"/>
    <dbReference type="InParanoid" id="G4N4E4"/>
    <dbReference type="OMA" id="SWAPFQK"/>
    <dbReference type="OrthoDB" id="338970at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051292">
        <property type="term" value="P:nuclear pore complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.440:FF:000001">
        <property type="entry name" value="Nuclear pore complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.450:FF:000002">
        <property type="entry name" value="Putative non-repetitive nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1880">
        <property type="entry name" value="Nucleoporin, helical C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.440">
        <property type="entry name" value="Nucleoporin, helical domain, central subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.450">
        <property type="entry name" value="Nucleoporin, helical domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007187">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014908">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004870">
        <property type="entry name" value="Nucleoporin_Nup155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042533">
        <property type="entry name" value="Nucleoporin_Nup155_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042537">
        <property type="entry name" value="Nucleoporin_Nup155_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042538">
        <property type="entry name" value="Nucleoporin_Nup155_C_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03177">
        <property type="entry name" value="Nucleoporin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08801">
        <property type="entry name" value="Nucleoporin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like N-terminal" evidence="14">
        <location>
            <begin position="127"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like C-terminal" evidence="13">
        <location>
            <begin position="673"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="29"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA52812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1415" mass="156873" checksum="5D3A1905A51FDC3A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4S0</accession>
    <name>G4N4S0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712692.1">
        <property type="nucleotide sequence ID" value="XM_003712644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4S0"/>
    <dbReference type="GeneID" id="12985154"/>
    <dbReference type="KEGG" id="mgr:MGG_16877"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16877"/>
    <dbReference type="HOGENOM" id="CLU_1938578_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4S0"/>
    <dbReference type="OrthoDB" id="10410820at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="130" mass="13924" checksum="4B865918B7E484F5" modified="2011-12-14" version="1">MPCRTKDKKLSPMQACSEIAYHSPSSSPSKTRQNLAGTVCLWVDLPANQIGPSPPVSPCSRRFGLWRPAVLATAISVSGRSSSPETGPQIDAGRTIGSCSSELVYSHLLSNATDARVVRQDKRAADRQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4S1</accession>
    <name>G4N4S1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_05158</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712693.1">
        <property type="nucleotide sequence ID" value="XM_003712645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4S1"/>
    <dbReference type="SMR" id="G4N4S1"/>
    <dbReference type="STRING" id="242507.G4N4S1"/>
    <dbReference type="GeneID" id="2675612"/>
    <dbReference type="KEGG" id="mgr:MGG_05158"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05158"/>
    <dbReference type="eggNOG" id="KOG0768">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_3_0_1"/>
    <dbReference type="InParanoid" id="G4N4S1"/>
    <dbReference type="OMA" id="DIWIAGA"/>
    <dbReference type="OrthoDB" id="250329at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="102"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="224"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA52886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="337" mass="35454" checksum="966FFDB68AA05BD5" modified="2011-12-14" version="1">MSNNSHTEVLVAGAIAAFTIDLLVYPLDTLKTRYQSQDYLDTYKKSGSSSSAIKNVPKGTFRGLYQGVGSVIIATLPAAGIFFTTYESAKSGFAKALPEGAPSPLVHALASGTAELASCAVLTPAEVIKQNAQMIRSNSGSSGGSTSGKSTSLQAFRMLQSAEGGAWRRLWTGYTALAARNLPFTAMQFPMFEYVRATIWRQRDDRRRSRKEAGGIEEGQGLLETGLVNGSSAALSGSVAAVLTTPTDVVKTRMMLLAGDQKSSGGGGGSNSSSSNNGGFRIARDVYRELGVRGLFRGGLFRAGWTALGSGLYLGTYEVAKVWLKGGKGTDKDEGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5E9</accession>
    <name>G4N5E9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable vacuolar protein sorting-associated protein 16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_05256</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712813.1">
        <property type="nucleotide sequence ID" value="XM_003712765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5E9"/>
    <dbReference type="SMR" id="G4N5E9"/>
    <dbReference type="FunCoup" id="G4N5E9">
        <property type="interactions" value="1069"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5E9"/>
    <dbReference type="GeneID" id="2675465"/>
    <dbReference type="KEGG" id="mgr:MGG_05256"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05256"/>
    <dbReference type="eggNOG" id="KOG2280">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008909_1_0_1"/>
    <dbReference type="InParanoid" id="G4N5E9"/>
    <dbReference type="OMA" id="WCGDDCL"/>
    <dbReference type="OrthoDB" id="1792at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000635">
        <property type="entry name" value="Probable vacuolar protein sorting-associated protein 16 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.780">
        <property type="entry name" value="Vps16, C-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016534">
        <property type="entry name" value="VPS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006925">
        <property type="entry name" value="Vps16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038132">
        <property type="entry name" value="Vps16_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006926">
        <property type="entry name" value="Vps16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04840">
        <property type="entry name" value="Vps16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04841">
        <property type="entry name" value="Vps16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007949">
        <property type="entry name" value="VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps16 N-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Vps16 C-terminal" evidence="3">
        <location>
            <begin position="502"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR007949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA53006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="829" mass="92994" checksum="56D50EFA0B933D31" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5F6</accession>
    <name>G4N5F6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DEAD/DEAH box helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16581</name>
        <name evidence="2" type="ORF">MGG_16995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711163.1">
        <property type="nucleotide sequence ID" value="XM_003711115.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715880.1">
        <property type="nucleotide sequence ID" value="XM_003715832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5F6"/>
    <dbReference type="STRING" id="242507.G4N5F6"/>
    <dbReference type="GeneID" id="12986163"/>
    <dbReference type="GeneID" id="12986600"/>
    <dbReference type="KEGG" id="mgr:MGG_16581"/>
    <dbReference type="KEGG" id="mgr:MGG_16995"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16581"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16995"/>
    <dbReference type="HOGENOM" id="CLU_2527913_0_0_1"/>
    <dbReference type="OrthoDB" id="4777017at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9410" checksum="4915C9B59340157E" modified="2011-12-14" version="1">MLEERPGREARNQSSRAAKKTSPVIMVVGTSGGKNILFIFPAAYSAEKITIIIIPLMSLRNNIKNKCDELGINFVEWASERPYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5H1</accession>
    <name>G4N5H1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U2 small nuclear ribonucleoprotein A'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_13209</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the U2 small nuclear ribonucleoprotein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711971.1">
        <property type="nucleotide sequence ID" value="XM_003711923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5H1"/>
    <dbReference type="SMR" id="G4N5H1"/>
    <dbReference type="FunCoup" id="G4N5H1">
        <property type="interactions" value="1233"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5H1"/>
    <dbReference type="GeneID" id="2684292"/>
    <dbReference type="KEGG" id="mgr:MGG_13209"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13209"/>
    <dbReference type="eggNOG" id="KOG1644">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061027_1_0_1"/>
    <dbReference type="InParanoid" id="G4N5H1"/>
    <dbReference type="OMA" id="PNYREYM"/>
    <dbReference type="OrthoDB" id="433501at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000026">
        <property type="entry name" value="U2 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044640">
        <property type="entry name" value="RU2A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552:SF6">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="248" mass="27859" checksum="6995D95BF136B5B8" modified="2011-12-14" version="1">MRLNADLINHSLSYLNPLKERELDLRGHRIPAIENLGVAGPQDAIDFTDNDILTLGNFPLSPRIRTLLLARNRIVSIQPALANAIPNLTNLQLASNNLSELADLDPLKGFKKLTHLVLMDNPVAKKENYRYWVLWRCPSVRFLDFQKVKQAEREHATEIFGTEAEPTELALKIIGTKASSLDKAAKSANAPSTAGSKLSRIKLTDEERQRLQERIKNAKSLDEILRLEKELNEGRLPAGIHASDMMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5T1</accession>
    <name>G4N5T1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716026.1">
        <property type="nucleotide sequence ID" value="XM_003715978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5T1"/>
    <dbReference type="GeneID" id="12986483"/>
    <dbReference type="KEGG" id="mgr:MGG_17029"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17029"/>
    <dbReference type="HOGENOM" id="CLU_2886266_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5T1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="63" mass="6861" checksum="E13E159D1AABE608" modified="2011-12-14" version="1">MRERFCSQVQRSAAQSVNVSGGAKGWSRPGTVILAAMQGMLARRERETDVRESAVIGEAGSWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6T2</accession>
    <name>G4N6T2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Importin-95</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Karyopherin-95</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_03668</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family. Importin beta-1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716218.1">
        <property type="nucleotide sequence ID" value="XM_003716170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6T2"/>
    <dbReference type="SMR" id="G4N6T2"/>
    <dbReference type="FunCoup" id="G4N6T2">
        <property type="interactions" value="1356"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N6T2"/>
    <dbReference type="GeneID" id="2676537"/>
    <dbReference type="KEGG" id="mgr:MGG_03668"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03668"/>
    <dbReference type="eggNOG" id="KOG1241">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008296_1_0_1"/>
    <dbReference type="InParanoid" id="G4N6T2"/>
    <dbReference type="OMA" id="QQYQERW"/>
    <dbReference type="OrthoDB" id="10263328at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042564">
        <property type="term" value="C:NLS-dependent protein nuclear import complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097718">
        <property type="term" value="F:disordered domain specific binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061676">
        <property type="term" value="F:importin-alpha family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006607">
        <property type="term" value="P:NLS-bearing protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051292">
        <property type="term" value="P:nuclear pore complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046822">
        <property type="term" value="P:regulation of nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060188">
        <property type="term" value="P:regulation of protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000027">
        <property type="entry name" value="Importin subunit beta-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00079884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00083566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA49899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="876" mass="95935" checksum="24CBD51311EBA6C6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6T4</accession>
    <name>G4N6T4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">FreB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_03667</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716220.1">
        <property type="nucleotide sequence ID" value="XM_003716172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6T4"/>
    <dbReference type="SMR" id="G4N6T4"/>
    <dbReference type="GeneID" id="2676536"/>
    <dbReference type="KEGG" id="mgr:MGG_03667"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03667"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010365_3_1_1"/>
    <dbReference type="InParanoid" id="G4N6T4"/>
    <dbReference type="OMA" id="WMDEVLR"/>
    <dbReference type="OrthoDB" id="4494341at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF12">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="329"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA49901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="629" mass="70518" checksum="F47BE90D984C01B0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N711</accession>
    <name>G4N711_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein phosphatase dullard</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716243.1">
        <property type="nucleotide sequence ID" value="XM_003716195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N711"/>
    <dbReference type="SMR" id="G4N711"/>
    <dbReference type="STRING" id="242507.G4N711"/>
    <dbReference type="GeneID" id="2676631"/>
    <dbReference type="KEGG" id="mgr:MGG_03646"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03646"/>
    <dbReference type="eggNOG" id="KOG1605">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020262_2_1_1"/>
    <dbReference type="InParanoid" id="G4N711"/>
    <dbReference type="OMA" id="HAHDEIT"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="PHI-base" id="PHI:11582"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009651">
        <property type="term" value="P:response to salt stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000043">
        <property type="entry name" value="General stress response phosphoprotein phosphatase Psr1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="331"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="505" mass="54325" checksum="96180357E5BB805E" modified="2011-12-14" version="1">MSRDADVQAHSTAHGSKEKETLTPEDGGSGRKGRGLLNVPSRSSSQRMQPSSTSTGLGGAATGESRDSVDGHSKESKGSQFGRRRRGSASSNHSGVANSQTNTPANSQPSSPPPQSQKRKKGGLLSLFGCCGVPDTANALENGDHPLPNHKVEKIPNRPATASRRTATPSDQATPTKTLYEKEQTQPTQSTSDSSRTKRVSASTTNQDQSTVGERESESKQQPLVGSGGPVVTVQPPQVSGIPESSAQQSQPPSQDTDGDVEMQDEGASQGDVAQQSVEAAQQKLPPPPPGPIPSSNAAEEPVASSDNDMIPAAVPEPPEQKYLLPPIQPRFKGKKCLVLDLDETLVHSSFKILHQADFTIPVEIEGNYHNVYVIKRPGVDQFMKRVGELYEVVVFTASVSKYGDPLLDQLDIHNVVHHRLFRESCYNHQGNYVKDLSQVGRDLKDTIIIDNSPTSYIFHPQHAVPISSWFSDAHDNELLDLIPVLEDLAGSNVQDVSLVLDVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7G6</accession>
    <name>G4N7G6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Multifunctional tryptophan biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="16">Anthranilate synthase component 2</fullName>
                <shortName evidence="16">AS</shortName>
                <ecNumber evidence="16">4.1.3.27</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">Anthranilate synthase, glutamine amidotransferase component</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">Indole-3-glycerol phosphate synthase</fullName>
                <shortName evidence="16">IGPS</shortName>
                <ecNumber evidence="16">4.1.1.48</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
                <shortName evidence="16">PRAI</shortName>
                <ecNumber evidence="16">5.3.1.24</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MGG_06425</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 16">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="16"/>
    <dbReference type="EC" id="4.1.1.48" evidence="16"/>
    <dbReference type="EC" id="5.3.1.24" evidence="16"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717142.1">
        <property type="nucleotide sequence ID" value="XM_003717094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7G6"/>
    <dbReference type="SMR" id="G4N7G6"/>
    <dbReference type="FunCoup" id="G4N7G6">
        <property type="interactions" value="378"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7G6"/>
    <dbReference type="MEROPS" id="C26.959"/>
    <dbReference type="GeneID" id="2684580"/>
    <dbReference type="KEGG" id="mgr:MGG_06425"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06425"/>
    <dbReference type="eggNOG" id="KOG0026">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007713_2_0_1"/>
    <dbReference type="InParanoid" id="G4N7G6"/>
    <dbReference type="OMA" id="EPIEWAN"/>
    <dbReference type="OrthoDB" id="524799at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000136">
        <property type="entry name" value="Multifunctional tryptophan biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000031">
        <property type="entry name" value="Multifunctional tryptophan biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016302">
        <property type="entry name" value="Anthranilate_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF4">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001382">
        <property type="entry name" value="TrpG-trpC-trpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 16" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 16" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 16" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="18">
        <location>
            <begin position="28"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Indole-3-glycerol phosphate synthase" evidence="19">
        <location>
            <begin position="256"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="N-(5'phosphoribosyl) anthranilate isomerase (PRAI)" evidence="20">
        <location>
            <begin position="593"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR001382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EHA50823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="764" mass="82364" checksum="9AE0F57D78BBFDAA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7N5</accession>
    <name>G4N7N5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">H/ACA ribonucleoprotein complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_03556</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9 10">Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
            <location evidence="1 10">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the GAR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716359.1">
        <property type="nucleotide sequence ID" value="XM_003716311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7N5"/>
    <dbReference type="SMR" id="G4N7N5"/>
    <dbReference type="FunCoup" id="G4N7N5">
        <property type="interactions" value="562"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7N5"/>
    <dbReference type="GeneID" id="2676695"/>
    <dbReference type="KEGG" id="mgr:MGG_03556"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03556"/>
    <dbReference type="eggNOG" id="KOG3262">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080002_1_0_1"/>
    <dbReference type="InParanoid" id="G4N7N5"/>
    <dbReference type="OMA" id="KPQDGIV"/>
    <dbReference type="OrthoDB" id="2187159at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034513">
        <property type="term" value="F:box H/ACA snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000454">
        <property type="term" value="P:snoRNA guided rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.230:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237:SF6">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237">
        <property type="entry name" value="NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="119"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="139"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00053712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00062786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA50040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="216" mass="21561" checksum="0DE8650AB60D46D7" modified="2011-12-14" version="1">MASRGAPRGRGGGGFGRGGGRGGFQQRDFGPPTSVVEMGKFVHACEGEMFCESINPKIPHFSAPIYLENKTAVGKVDEILGPLNQVFFTIKPSEGIQAGAFKAGDRFYIAQEKLLPLERFLPKPKPPPGSVPKVKKPAGGRGGRGGPGGRGRGAPRGGGGFGGRGGGGGFSRGGGGGFSRGGGRGGGGFTRGAGSGGFSRGGGRGRGGGGFSRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7Q2</accession>
    <name>G4N7Q2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome assembly protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_03541</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for efficient biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RSA3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716376.1">
        <property type="nucleotide sequence ID" value="XM_003716328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7Q2"/>
    <dbReference type="SMR" id="G4N7Q2"/>
    <dbReference type="STRING" id="242507.G4N7Q2"/>
    <dbReference type="GeneID" id="2676618"/>
    <dbReference type="KEGG" id="mgr:MGG_03541"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03541"/>
    <dbReference type="eggNOG" id="ENOG502SBU9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_181714_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7Q2"/>
    <dbReference type="OrthoDB" id="69550at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051898">
        <property type="entry name" value="Ribosome_Assembly_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028217">
        <property type="entry name" value="Rsa3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28127">
        <property type="entry name" value="RIBOSOME ASSEMBLY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28127:SF1">
        <property type="entry name" value="RIBOSOME ASSEMBLY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14615">
        <property type="entry name" value="Rsa3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Ribosome-assembly protein 3 C-terminal" evidence="9">
        <location>
            <begin position="22"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA50057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="85" mass="9233" checksum="F811C34B79246BF7" modified="2011-12-14" version="1">MSTNNSKQTKPAATQKTAPPEFEGFYLQQATKEFAEDLDKIRAADDFKNDAVPMLVHALKQGATMFSPAEQARIVEGTSALGIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7Q8</accession>
    <name>G4N7Q8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inheritance of peroxisomes protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_03535</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for peroxisome inheritance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the INP1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716382.1">
        <property type="nucleotide sequence ID" value="XM_003716334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7Q8"/>
    <dbReference type="STRING" id="242507.G4N7Q8"/>
    <dbReference type="GeneID" id="2676612"/>
    <dbReference type="KEGG" id="mgr:MGG_03535"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03535"/>
    <dbReference type="eggNOG" id="ENOG502S7ZC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016546_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7Q8"/>
    <dbReference type="OMA" id="PMPCAWE"/>
    <dbReference type="OrthoDB" id="4097008at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005780">
        <property type="term" value="C:extrinsic component of intraperoxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045033">
        <property type="term" value="P:peroxisome inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024758">
        <property type="entry name" value="Inp1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12634">
        <property type="entry name" value="Inp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="247"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="348"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="462"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="494"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="699" mass="75910" checksum="97080FE54291249E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7Y1</accession>
    <name>G4N7Y1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-1-phosphate guanyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">GTP-mannose-1-phosphate guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Translation initiation factor eIF2B subunit epsilon</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">eIF2B GDP-GTP exchange factor subunit epsilon</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_03517</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716402.1">
        <property type="nucleotide sequence ID" value="XM_003716354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7Y1"/>
    <dbReference type="SMR" id="G4N7Y1"/>
    <dbReference type="FunCoup" id="G4N7Y1">
        <property type="interactions" value="1167"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7Y1"/>
    <dbReference type="GeneID" id="2676818"/>
    <dbReference type="KEGG" id="mgr:MGG_03517"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03517"/>
    <dbReference type="eggNOG" id="KOG1461">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012507_1_0_1"/>
    <dbReference type="InParanoid" id="G4N7Y1"/>
    <dbReference type="OMA" id="LAQSCKI"/>
    <dbReference type="OrthoDB" id="424572at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <location>
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        </location>
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        <location>
            <begin position="500"/>
            <end position="550"/>
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        <location>
            <begin position="1"/>
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            <begin position="535"/>
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        </location>
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        <source>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        <source>
            <dbReference type="EMBL" id="EHA50083.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    <sequence length="733" mass="79584" checksum="ADED7421A615B13C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N911</accession>
    <name>G4N911_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_1124746_0_0_1"/>
    <dbReference type="InParanoid" id="G4N911"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
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        <location>
            <begin position="22"/>
            <end position="247"/>
        </location>
    </feature>
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        <location>
            <begin position="40"/>
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        </location>
    </feature>
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        </location>
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        <location>
            <begin position="75"/>
            <end position="107"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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            <end position="175"/>
        </location>
    </feature>
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        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="247" mass="26372" checksum="736A0B9550107FCD" modified="2011-12-14" version="1">MRVSSWFKFTVLAALGPQALAEVLADHGADKAGLVSRELPYDLGEPAPCPDDKGRLGSYPPRIPPSILKKLIDGSKSSSSSSSSSSSSSASSSSSSSSSSSSSSSSSKVRSKRSQDCREKLPASAENDHDEKGRSPQWRKGKGLPQNRWSNHMMPGIGEHEGFPRQSNSAPQGQITARGDYPRSGKLGVDAEGNAIYKARHGRSTRLVARGDDDPDSGRGGVDLDGNPIYKTAKGHRFHRNRKLQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9J0</accession>
    <name>G4N9J0_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">BolA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_14875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716701.1">
        <property type="nucleotide sequence ID" value="XM_003716653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9J0"/>
    <dbReference type="SMR" id="G4N9J0"/>
    <dbReference type="FunCoup" id="G4N9J0">
        <property type="interactions" value="275"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9J0"/>
    <dbReference type="GeneID" id="12984576"/>
    <dbReference type="KEGG" id="mgr:MGG_14875"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14875"/>
    <dbReference type="eggNOG" id="KOG3348">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109462_4_0_1"/>
    <dbReference type="InParanoid" id="G4N9J0"/>
    <dbReference type="OMA" id="VHAFSQK"/>
    <dbReference type="OrthoDB" id="4983at2759"/>
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        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BOL2"/>
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        <property type="entry name" value="BolA"/>
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        <property type="entry name" value="BolA-like_sf"/>
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        <property type="entry name" value="BOLA-LIKE PROTEIN 2"/>
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        <property type="match status" value="1"/>
    </dbReference>
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            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="110" mass="11755" checksum="F69EB29D2C4F322F" modified="2011-12-14" version="1">MAESEITEASIKDALTQRLKAIHAEVTDMSGGCGQAFTVLIVSSEFAGKNSLKRHRLVNAAMKDEIARIHAWTAKCQTPEEWERDKASATGADGPSMDGTVGGHVDGVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAH5</accession>
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            <fullName evidence="4">FAD/NAD(P)-binding domain-containing protein</fullName>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717632.1">
        <property type="nucleotide sequence ID" value="XM_003717584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAH5"/>
    <dbReference type="GeneID" id="2680673"/>
    <dbReference type="KEGG" id="mgr:MGG_09719"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09719"/>
    <dbReference type="eggNOG" id="ENOG502T7AG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020220_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000009058">
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    </dbReference>
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        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
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        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
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        <location>
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            <end position="41"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="736"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="863" mass="95040" checksum="781F84021C77D0AA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAK8</accession>
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    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717665.1">
        <property type="nucleotide sequence ID" value="XM_003717617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAK8"/>
    <dbReference type="GeneID" id="12986594"/>
    <dbReference type="KEGG" id="mgr:MGG_17283"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17283"/>
    <dbReference type="HOGENOM" id="CLU_2638536_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAK8"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="77" mass="8197" checksum="BA80A5904476AB68" modified="2011-12-14" version="1">MIPDGGYNSTGPNHPPLGQALGCMISIAGPQQMSESDKPYTPFHPGTLLRNVRNHVVPSQLLYAVLAMAAPLLVTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAQ5</accession>
    <name>G4NAQ5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17028</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716017.1">
        <property type="nucleotide sequence ID" value="XM_003715969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAQ5"/>
    <dbReference type="GeneID" id="12986480"/>
    <dbReference type="KEGG" id="mgr:MGG_17028"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17028"/>
    <dbReference type="HOGENOM" id="CLU_1835538_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAQ5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="140" mass="15167" checksum="2241CA9474AD5202" modified="2011-12-14" version="1">MNLPNSGCLLAGAQGLALATRHTPGSFLCKHRVTCSIEPRKHDAYMGTLTNYASHNIIADAADHNQDGGWETHQHGDDTNNRFGGDFHVLSSQLSVRQGRSAVFRHLAILSRPLARPLIPSRGVSQSMTGTLHIHNVPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBB7</accession>
    <name>G4NBB7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Seed imbibition protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_11554</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-galactosyl-(1-&gt;3)-1D-myo-inositol + sucrose = raffinose + myo-inositol</text>
            <dbReference type="Rhea" id="RHEA:20161"/>
            <dbReference type="ChEBI" id="CHEBI:16634"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:17505"/>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
            <dbReference type="EC" id="2.4.1.82"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolases 36 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718463.1">
        <property type="nucleotide sequence ID" value="XM_003718415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBB7"/>
    <dbReference type="SMR" id="G4NBB7"/>
    <dbReference type="GeneID" id="2675080"/>
    <dbReference type="KEGG" id="mgr:MGG_11554"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11554"/>
    <dbReference type="eggNOG" id="ENOG502QPVE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006630_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBB7"/>
    <dbReference type="OMA" id="WHIHTNS"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047274">
        <property type="term" value="F:galactinol-sucrose galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008811">
        <property type="entry name" value="Glycosyl_hydrolases_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268:SF32">
        <property type="entry name" value="GALACTINOL--SUCROSE GALACTOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05691">
        <property type="entry name" value="Raffinose_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="289"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA48879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="908" mass="99884" checksum="DB89A9DD8AB5AD01" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBP5</accession>
    <name>G4NBP5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718537.1">
        <property type="nucleotide sequence ID" value="XM_003718489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBP5"/>
    <dbReference type="SMR" id="G4NBP5"/>
    <dbReference type="FunCoup" id="G4NBP5">
        <property type="interactions" value="18"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NBP5"/>
    <dbReference type="GeneID" id="2674659"/>
    <dbReference type="KEGG" id="mgr:MGG_00520"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00520"/>
    <dbReference type="eggNOG" id="KOG4455">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110781_4_0_1"/>
    <dbReference type="InParanoid" id="G4NBP5"/>
    <dbReference type="OMA" id="YPGFLFY"/>
    <dbReference type="OrthoDB" id="16510at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008504">
        <property type="entry name" value="Emc6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029008">
        <property type="entry name" value="EMC6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07019">
        <property type="entry name" value="EMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA48953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="118" mass="12957" checksum="71FFF469712516B5" modified="2011-12-14" version="1">MPSERDYQIAPIVQESVMHNTKIVSNVQTLTASLFGVAAGILGLESYSGFLFYVIFSFLTTAIFYVFRVAPTSLSAGKGFLDSSRYFKGPFELWTGGLFGGLAGFILTWTLFYGLVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC29</accession>
    <name>G4NC29_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718616.1">
        <property type="nucleotide sequence ID" value="XM_003718568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC29"/>
    <dbReference type="GeneID" id="2674095"/>
    <dbReference type="KEGG" id="mgr:MGG_00451"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00451"/>
    <dbReference type="eggNOG" id="ENOG502S9JB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058251_0_0_1"/>
    <dbReference type="InParanoid" id="G4NC29"/>
    <dbReference type="OMA" id="IDDQTWF"/>
    <dbReference type="OrthoDB" id="2101715at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="319" mass="36124" checksum="90A209F2980B3401" modified="2011-12-14" version="1">MTRLFPRIHAFEIDDQPWFPPFLRQRVQTVLRLTWEASIPILQSSSPAERVARLLGEHLDSIDDYGFIDFCAGAGGPTPAIERHVNANRDPTKPGIPFIMTDIYPHVKSWERDAARSPNISYVTKPVDATAAPDFLLDRFRGSKDSSSSTGGDGIVSYAEMATMKETDHVIKPRKIFRLFNLAFHHFDDPLAKSILADTVKTSDAFGIFELQQRTFSSFMMLNILYLSIFVVAPFYALMNLDLVAFVFTWFLPIIPVVITFDGYISSLRTRTPDEVEALLRTCGAGNVEDWEIRGGTERHFWPFGYLEWIICTKKSSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCA7</accession>
    <name>G4NCA7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">homogentisate 1,2-dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_00431</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.5" evidence="4"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718640.1">
        <property type="nucleotide sequence ID" value="XM_003718592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCA7"/>
    <dbReference type="SMR" id="G4NCA7"/>
    <dbReference type="STRING" id="242507.G4NCA7"/>
    <dbReference type="GeneID" id="2675249"/>
    <dbReference type="KEGG" id="mgr:MGG_00431"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00431"/>
    <dbReference type="eggNOG" id="KOG1417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027174_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCA7"/>
    <dbReference type="OMA" id="WQGNYYP"/>
    <dbReference type="OrthoDB" id="1689029at2759"/>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07000">
        <property type="entry name" value="cupin_HGO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000053">
        <property type="entry name" value="Homogentisate 1,2-dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046451">
        <property type="entry name" value="HgmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046452">
        <property type="entry name" value="HgmA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01015">
        <property type="entry name" value="hmgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056:SF0">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20510">
        <property type="entry name" value="HgmA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase N-terminal" evidence="15">
        <location>
            <begin position="13"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase N-terminal" evidence="15">
        <location>
            <begin position="115"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase C-terminal" evidence="14">
        <location>
            <begin position="332"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="79"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA49056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="503" mass="55012" checksum="EA136E21DFAEB694" modified="2011-12-14" version="1">MPATEFEFKEKYRYQNGFDSYLESEAVPGALPIAQNSPQKPPHGLYAEKLSGTAFTAPRNENKQSWLYRILPSCAHPPFRVKGQAGEHDVENQPPTPPITPGQPLTPGQQPQHEHKDEMARFAPLSRLHYIPNQLRWDPFDHDPQSDFVSGLHLIAGAGEPTLKHGIGMFVYAAGKSMSTSSAFYSADGDLLIVAQSGVLDIRTELGWLLVRPLEIAVIPRGIRFQVLLPEGTGPARGYALELYQGHFALPELGPIGSNGLANARDFQAPVACFSEDHGPTAFSAGPSAPRDGYEVTAKFNNTLFATRQAHTPFDVVAWHGNYYPFKYDLGRFNTIGAISYDHPDPSIFTVLTAPSDHAGTAVADFVIFPPRWLVGEDTFRPPWYHRNTMSEFMGLITGDYDAKKGGKGGFVPGGASLHNVMSGHGPDAASYEGAREAELKPAKVGAGSCAFMFESCFMVGVTDWGLRTCQKVQEGYSQESWGGVKTYWKRPEGASADVHLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCB3</accession>
    <name>G4NCB3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718646.1">
        <property type="nucleotide sequence ID" value="XM_003718598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCB3"/>
    <dbReference type="SMR" id="G4NCB3"/>
    <dbReference type="GeneID" id="2674884"/>
    <dbReference type="KEGG" id="mgr:MGG_00426"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00426"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_0_1"/>
    <dbReference type="InParanoid" id="G4NCB3"/>
    <dbReference type="OMA" id="PGFFATD"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF32">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="272" mass="29281" checksum="A4A768CCCB80EB70" modified="2011-12-14" version="1">MTLSTSHKIVIITGANKGLGFEAVKRFLASDNKYHIFLGSRDLAKGQKAVQKALGEVPSDKSTVEALQYDVESDESIQEAYETVRSRVDRVDVLINNAGVMLDQQIERGNMSTREAFNRSWDVNVAGAHITTSTFLPLLLKSPDPRVVFNTSGVSSLAHAADPCHFTYRAPPAGVPKPAGTVSYRASKAGLNMVMLEWARMLRDDGVKVWAVAPGFFATDIGEGDPGAMRKMGAGDPAVGGEALVDVVEGRRDGDVGRVCNMAPYGVKVQAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCC1</accession>
    <name>G4NCC1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00419</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718654.1">
        <property type="nucleotide sequence ID" value="XM_003718606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCC1"/>
    <dbReference type="SMR" id="G4NCC1"/>
    <dbReference type="FunCoup" id="G4NCC1">
        <property type="interactions" value="61"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NCC1"/>
    <dbReference type="GeneID" id="2674937"/>
    <dbReference type="KEGG" id="mgr:MGG_00419"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00419"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="InParanoid" id="G4NCC1"/>
    <dbReference type="OMA" id="DIAWYES"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF201">
        <property type="entry name" value="MFS AFLATOXIN EFFLUX PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="44"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA49070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="552" mass="58502" checksum="6702E7AD4CBEA813" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCV5</accession>
    <name>G4NCV5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="18">ISWI chromatin-remodeling complex ATPase ISW2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_01012</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717932.1">
        <property type="nucleotide sequence ID" value="XM_003717884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCV5"/>
    <dbReference type="SMR" id="G4NCV5"/>
    <dbReference type="FunCoup" id="G4NCV5">
        <property type="interactions" value="1118"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NCV5"/>
    <dbReference type="GeneID" id="2674262"/>
    <dbReference type="KEGG" id="mgr:MGG_01012"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01012"/>
    <dbReference type="eggNOG" id="KOG0385">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000315_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCV5"/>
    <dbReference type="OMA" id="VHDYQFF"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031010">
        <property type="term" value="C:ISWI-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17997">
        <property type="entry name" value="DEXHc_SMARCA1_SMARCA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000082">
        <property type="entry name" value="ISWI chromatin remodeling complex ATPase ISW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000022">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase CHR11 isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000002">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase CHR11 isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1190:FF:000005">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase ISW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000234">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase ISW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.30:FF:000003">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase ISW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1190">
        <property type="entry name" value="iswi atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.30">
        <property type="entry name" value="ISWI, HAND domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044754">
        <property type="entry name" value="Isw1/2_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015194">
        <property type="entry name" value="ISWI_HAND-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036306">
        <property type="entry name" value="ISWI_HAND-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015195">
        <property type="entry name" value="SLIDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09110">
        <property type="entry name" value="HAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09111">
        <property type="entry name" value="SLIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101224">
        <property type="entry name" value="HAND domain of the nucleosome remodeling ATPase ISWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="198"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="494"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="17">
        <location>
            <begin position="863"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="130"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="840"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1040"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="920"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1042"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1087"/>
            <end position="1113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA48348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1128" mass="128509" checksum="5E4A1044C991FA61" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDD1</accession>
    <name>G4NDD1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718004.1">
        <property type="nucleotide sequence ID" value="XM_003717956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDD1"/>
    <dbReference type="GeneID" id="2674510"/>
    <dbReference type="KEGG" id="mgr:MGG_00947"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00947"/>
    <dbReference type="eggNOG" id="ENOG502T426">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111200_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDD1"/>
    <dbReference type="OMA" id="WKGMVED"/>
    <dbReference type="OrthoDB" id="3993201at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="204" mass="21490" checksum="B3BA1DC00A48A06E" modified="2011-12-14" version="1">MTRVTSMAKFTRLTASPSVVRPTSMASGASKASASLAHELSADGRSSDHESSRRGMMTTHGPARVQPNPNRTIPLMQSFFHSSPSQGASLATARSGPSTLDFTVLPNMSTAMPDLFSAVPRVPLLPDNFSPNRSAALFPAEVPDAPLPAPEISVIAQHPDKVFSALTEVEGIGIDGIELKFVHEPVASKSSEGGSMIRNVWAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDJ7</accession>
    <name>G4NDJ7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Multidrug resistance protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_00239</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718866.1">
        <property type="nucleotide sequence ID" value="XM_003718818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDJ7"/>
    <dbReference type="SMR" id="G4NDJ7"/>
    <dbReference type="FunCoup" id="G4NDJ7">
        <property type="interactions" value="759"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NDJ7"/>
    <dbReference type="GeneID" id="2674764"/>
    <dbReference type="KEGG" id="mgr:MGG_00239"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00239"/>
    <dbReference type="eggNOG" id="KOG0055">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_17_2_1"/>
    <dbReference type="InParanoid" id="G4NDJ7"/>
    <dbReference type="OMA" id="PDIDACC"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000913">
        <property type="entry name" value="ABC multidrug transporter SitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000479">
        <property type="entry name" value="Multidrug resistance protein 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="670"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="716"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="785"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="817"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="30"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="355"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="672"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="994"/>
            <end position="1235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA49282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1240" mass="130559" checksum="F58A14CA05E78DCC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEC4</accession>
    <name>G4NEC4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718191.1">
        <property type="nucleotide sequence ID" value="XM_003718143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEC4"/>
    <dbReference type="GeneID" id="5050650"/>
    <dbReference type="KEGG" id="mgr:MGG_11492"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11492"/>
    <dbReference type="HOGENOM" id="CLU_2121565_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEC4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="114" mass="12504" checksum="375AA46F7A92974A" modified="2011-12-14" version="1">MPRQARKKKKRGPAGDRAIGSGDVAQELLARPEVDCIADWVLAGREGGRREPGQAAGACFPGFWIRLHRVVVRTAKTPPPLFEEEHEAGDDAHEYDANDPNDGLVVESHFPQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEH5</accession>
    <name>G4NEH5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_00103</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719036.1">
        <property type="nucleotide sequence ID" value="XM_003718988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEH5"/>
    <dbReference type="SMR" id="G4NEH5"/>
    <dbReference type="STRING" id="242507.G4NEH5"/>
    <dbReference type="GeneID" id="2674325"/>
    <dbReference type="KEGG" id="mgr:MGG_00103"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00103"/>
    <dbReference type="eggNOG" id="KOG0417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_13_3_1"/>
    <dbReference type="InParanoid" id="G4NEH5"/>
    <dbReference type="OMA" id="ADLHTWH"/>
    <dbReference type="OrthoDB" id="9978460at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000060">
        <property type="entry name" value="Ubiquitin conjugating enzyme (UbcB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA49452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="169" mass="18416" checksum="581437BC2DDB0C15" modified="2011-12-14" version="1">MASQKRVQKELADCMTNPPPGMTVSLPSDADIFTWHVTLAGPADTAYAGGQYGLVVKLPADYPFKAPIITFATRIYHPNVTNDSAGNICISALKPENWKPASKLLGVLEAVRSLLVEPNPDDPLEARIAEEYKSNRPEFDKNAKSYVQRYAKGPPTFAAPQAEVAKESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEP5</accession>
    <name>G4NEP5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc finger FYVE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718259.1">
        <property type="nucleotide sequence ID" value="XM_003718211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEP5"/>
    <dbReference type="SMR" id="G4NEP5"/>
    <dbReference type="STRING" id="242507.G4NEP5"/>
    <dbReference type="GeneID" id="2674245"/>
    <dbReference type="KEGG" id="mgr:MGG_00741"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00741"/>
    <dbReference type="eggNOG" id="KOG1818">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037982_1_1_1"/>
    <dbReference type="InParanoid" id="G4NEP5"/>
    <dbReference type="OMA" id="TRCWYEM"/>
    <dbReference type="OrthoDB" id="5407799at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603">
        <property type="entry name" value="ABSCISSION/NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603:SF1">
        <property type="entry name" value="ABSCISSION_NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22586">
        <property type="entry name" value="ANCHR-like_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="44404" checksum="E5747661F7FB542C" modified="2011-12-14" version="1">MASNNGGNSERDLLDRLNALKPGSGTQNFAPKQDVLSDRLRALRNQSSDGSSSSAVLKTSGSTAESQVGKHTSSLTAGSPLPLGSAPVAAGTEPGEDEEEEDDDGFMSDLGDDGTLEDYLEDLELDLEEGNDEVSNQQPPSKPADGEGHAEDDAKRIAAVLARIGKGGSALPPSPSPGAHQAPRRLDVQVGSAGDDSEDDKRNQAEAENIVSQAFDEAKFDREISTPLGENSEEQRPLSSQRSLSTSHEQDARRPDDRQASPLDDAPTAAKESLSLPAVPNSLPGPAPTTTTTATPVTTGDDFESDISRRLAALRGLGGSGSGGDGGLALPSVPSFQPAANNNNNESRVKSTGGYTDEDEEGWCLICLEDATSICDGCDGDVYCDGCWWDMHLGPEAAFDGSHKRWFFIKERRRRRALPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NES0</accession>
    <name>G4NES0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Haloacid dehalogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_00065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719077.1">
        <property type="nucleotide sequence ID" value="XM_003719029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NES0"/>
    <dbReference type="SMR" id="G4NES0"/>
    <dbReference type="STRING" id="242507.G4NES0"/>
    <dbReference type="GeneID" id="2675068"/>
    <dbReference type="KEGG" id="mgr:MGG_00065"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00065"/>
    <dbReference type="eggNOG" id="KOG3085">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_8_0_1"/>
    <dbReference type="InParanoid" id="G4NES0"/>
    <dbReference type="OMA" id="WERTIVG"/>
    <dbReference type="OrthoDB" id="444127at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.720">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051828">
        <property type="entry name" value="HAD-like_hydrolase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044924">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46191:SF2">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="49944" checksum="254BD9D51093B90D" modified="2011-12-14" version="1">MPLQRAPLERFVRQSGPRNILLCLDAFDTLIRPRRPVAEQYAQVADQCGLTGITPAQVQATFRNAFKQEAKKNPNYGKATNLGATRWWTNVITNTFSPFLKPGQDIPKELAPRLLHRFSSDEGYELIEPNLPETLRLLWDGQQHADWNLVVGLVSNCDDRILGIMESLGLRVGPLRYGNLTVLRPKGDREATGQFLRSSFEGDATEALEDVASRRRKQSVSLVRKSPGLPGSDAIGAAASLDTAVTQSEAPRYDLDFTLMSYDVGHEKPDPEIFVSAQEMGDLVLKSSVGQPLQPTGMSRSSDHNDGEMTTARVDILHSRSNKPWLNWINIMVGDDLKTDAAGALSTSAGFWNCCILDPEGKHKPTVEAGIESTQLNRSMTDIDHQGKHQLLKAMAQNQLSVGRPEGFLMRIDSVCDLIMRIRRGMKQSPEAIPQSLLQKLAESASHRDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEX4</accession>
    <name>G4NEX4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphatidylethanolamine-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718284.1">
        <property type="nucleotide sequence ID" value="XM_003718236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEX4"/>
    <dbReference type="STRING" id="242507.G4NEX4"/>
    <dbReference type="GeneID" id="2674966"/>
    <dbReference type="KEGG" id="mgr:MGG_00721"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00721"/>
    <dbReference type="eggNOG" id="ENOG502S6VR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043994_4_3_1"/>
    <dbReference type="InParanoid" id="G4NEX4"/>
    <dbReference type="OMA" id="GTLLHWM"/>
    <dbReference type="OrthoDB" id="2506647at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF82">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466877" description="Phosphatidylethanolamine-binding protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="41032" checksum="CBA5D1E0CDCF057D" modified="2011-12-14" version="1">MIFSYLSILAAAGGALAVTPPGFSPGVQAPLFVLYSDSIAALNGATMSKMVTAKEPFVGTEKKLTGKSYAVIMVDMDVPTSQPPKTRSLLHWMQTDLVPVDQPTTINTTAGTTTVYPVSNLKRVIAAAPYFGPDPPARVPLNHRYTQVLIDTSNVGQEQMRILSKAATKREDFNVAEVLSAANIPTDKIVAGNFFQVTNNGPAQTGGYPSTPKPGSCPSSPPSSNATKPMPQPAPQPKPPAPAPVPMPAPGMRPNATRTNTTMPRPAAPGNGTSPAMPKSPAPGNGTNPAMPKSPAPGNGTNPAMPKSPAPGNGTNPAMPKSPAPGNGTNPTAPKPGPLNPAVPKSPVPGNGTKPMPGLGSNGTMPKPGMSPQPAIPPVNAKASSLSAAASVLLASVAFCILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF08</accession>
    <name>G4NF08_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_00033</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719111.1">
        <property type="nucleotide sequence ID" value="XM_003719063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF08"/>
    <dbReference type="SMR" id="G4NF08"/>
    <dbReference type="GeneID" id="2674985"/>
    <dbReference type="KEGG" id="mgr:MGG_00033"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00033"/>
    <dbReference type="eggNOG" id="ENOG502RY03">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_5_2_1"/>
    <dbReference type="InParanoid" id="G4NF08"/>
    <dbReference type="OMA" id="EKCSFWG"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466204" description="AB hydrolase-1 domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="86"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="5">
        <location>
            <begin position="450"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA49527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="57913" checksum="D7FC277BCE673F14" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFN9</accession>
    <name>G4NFN9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_08766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719213.1">
        <property type="nucleotide sequence ID" value="XM_003719165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFN9"/>
    <dbReference type="GeneID" id="2678918"/>
    <dbReference type="KEGG" id="mgr:MGG_08766"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08766"/>
    <dbReference type="eggNOG" id="ENOG502RC1C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_746121_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFN9"/>
    <dbReference type="OMA" id="MHEESYL"/>
    <dbReference type="OrthoDB" id="3140657at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42057">
        <property type="entry name" value="F-BOX DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_4G00200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42057:SF2">
        <property type="entry name" value="F-BOX DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_4G00200)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="42621" checksum="207FA6C9870748DE" modified="2011-12-14" version="1">MDLRNILTPSYPIQGGSLAWKGHQRLTKETKIQVCEILQARDDMDSLHSLAAVSKEFYTIATGLFQQTVTLEPTDTSIRHLKICMENPGLARRVRRIVIKSVHPAFDALGVWPYRFPGQHGDEHAQDWEAVVADLHRLPALESVVLTFTTLCADQRDDPDEEQPVTYICEPPEVRNWILKVVFDALAAINDIPGRRIVSFTVMNLQNKIHEAASLPAFTSVISRLRELRVEVVTEVIPHLGSRPGEEEDKKEYWELDMQIRLNFWADFNRFWLAPAQATLQRLSVSCLDPFGVVPRWDLSALHFPHLQHLELERFTFSYRSQVEWIAAHKTLRTLWLHGCPIVQQWRTRGEYESELDVGALVLHSAQPRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG44</accession>
    <name>G4NG44_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="16">Cytochrome P450</fullName>
                <ecNumber evidence="16">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="16">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MGG_10879</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 16">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="16">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16 17">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="16"/>
    <dbReference type="EC" id="1.6.2.4" evidence="16"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719368.1">
        <property type="nucleotide sequence ID" value="XM_003719320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG44"/>
    <dbReference type="SMR" id="G4NG44"/>
    <dbReference type="STRING" id="242507.G4NG44"/>
    <dbReference type="GeneID" id="2676401"/>
    <dbReference type="KEGG" id="mgr:MGG_10879"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10879"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_7_0_1"/>
    <dbReference type="InParanoid" id="G4NG44"/>
    <dbReference type="OMA" id="HSMMLDI"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000040">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000198">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 16" id="KW-0274">FAD</keyword>
    <keyword evidence="5 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 16" id="KW-0288">FMN</keyword>
    <keyword evidence="4 16 17" id="KW-0349">Heme</keyword>
    <keyword evidence="12 16 17" id="KW-0408">Iron</keyword>
    <keyword evidence="7 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 16" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 16" id="KW-0521">NADP</keyword>
    <keyword evidence="11 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="19">
        <location>
            <begin position="506"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="20">
        <location>
            <begin position="693"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="483"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="17">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EHA47001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1089" mass="120261" checksum="73B25CBAAD128529" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG46</accession>
    <name>G4NG46_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peroxidase</fullName>
            <ecNumber evidence="10">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_10877</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peroxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719370.1">
        <property type="nucleotide sequence ID" value="XM_003719322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG46"/>
    <dbReference type="SMR" id="G4NG46"/>
    <dbReference type="STRING" id="242507.G4NG46"/>
    <dbReference type="GeneID" id="2676399"/>
    <dbReference type="KEGG" id="mgr:MGG_10877"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10877"/>
    <dbReference type="eggNOG" id="ENOG502QT8W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041038_0_1_1"/>
    <dbReference type="InParanoid" id="G4NG46"/>
    <dbReference type="OMA" id="INSADLW"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF48">
        <property type="entry name" value="PEROXIDASE 16-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006991563" description="Peroxidase" evidence="10">
        <location>
            <begin position="27"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="11">
        <location>
            <begin position="55"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA47003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="264" mass="28023" checksum="7FA61DCA55AC4B7B" modified="2011-12-14" version="1">MLASLSSSSLLVASLLFVTAPVPVNGNKLCNPWKPVVADLKASFKGCNADARMAMRAAFHDCFPGSCDGSLILANECNDRPDDNGPLVPICDTLAQKAIDFKVGTADLIQAAGVVAITSCAGPRTYFYVGRKDSSVPSPEGQLPNSESTAQQQIDACKAKGFTTTDLVAMVGAHSAGVSQQGLSFDSTPEKLDSTVFYPETASEKGPTSLQSDYALSNDTQTKTAWKNMGRSNALWRAQFVTTMRKVTLMGNTVKSLTDCSYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGH5</accession>
    <name>G4NGH5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="3">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_04311</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 2',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:194156"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:77644"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719499.1">
        <property type="nucleotide sequence ID" value="XM_003719451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGH5"/>
    <dbReference type="SMR" id="G4NGH5"/>
    <dbReference type="FunCoup" id="G4NGH5">
        <property type="interactions" value="73"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGH5"/>
    <dbReference type="GeneID" id="2677101"/>
    <dbReference type="KEGG" id="mgr:MGG_04311"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04311"/>
    <dbReference type="eggNOG" id="KOG1528">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033446_1_1_1"/>
    <dbReference type="InParanoid" id="G4NGH5"/>
    <dbReference type="OMA" id="MSYQQER"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052829">
        <property type="term" value="F:inositol-1,3,4-trisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004441">
        <property type="term" value="F:inositol-1,4-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042538">
        <property type="term" value="P:hyperosmotic salinity response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016078">
        <property type="term" value="P:tRNA decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000015">
        <property type="entry name" value="3',5'-bisphosphate nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000003">
        <property type="entry name" value="PAP-specific phosphatase HAL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006239">
        <property type="entry name" value="DPNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01330">
        <property type="entry name" value="bisphos_HAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="407" mass="43412" checksum="4882C499D8C3FE14" modified="2011-12-14" version="1">MFTRETTKRHHLLSRPLFWTSLAALALAFILARVIPRLDLLGNHLRTQSTTIKMATYAKELEVAQLAVQRAAILTKRVFNEKAKGTVSKDDKSPVTIGDFGAQALIIAALKANFPEDEIVAEEEADALRGDEALKKTIWELVRTTKLSDEQAEKTLGGAIGSVEEMLELIDRGKSKGGDKGRIWAIDPIDGTKGFLRGGQYAVCLGLMVDGDVKVGVLGCPNLPVDDSAPLTADLGTNATDEGRGVLFSGVLGQGANSRPLTTGGLADPIKKISMKPLADMASATFCESVEAGHSSQGEAAQIAQKLGITNPSVRMDSQAKYGSIARGAGDIYLRLPTSKTYQEKIWDHAAGDLIVREAGGQVTDTEGRRLDFSKGRTLAENKGVVAAPAAVHDKVLKAVQEVLGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGK2</accession>
    <name>G4NGK2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Carrier protein YMC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_04103</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719729.1">
        <property type="nucleotide sequence ID" value="XM_003719681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGK2"/>
    <dbReference type="SMR" id="G4NGK2"/>
    <dbReference type="STRING" id="242507.G4NGK2"/>
    <dbReference type="GeneID" id="2677603"/>
    <dbReference type="KEGG" id="mgr:MGG_04103"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04103"/>
    <dbReference type="eggNOG" id="KOG0762">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_16_4_1"/>
    <dbReference type="InParanoid" id="G4NGK2"/>
    <dbReference type="OMA" id="VYRESGW"/>
    <dbReference type="OrthoDB" id="193856at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF57">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="15"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="126"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="223"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA47362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="318" mass="34965" checksum="8E44686BE0AB94F8" modified="2011-12-14" version="1">MSSEAKAVPVEPAPAKNYKGFVAGVFSGIAKLSVGHPFDTIKVRLQTTDASRFSGPLQCLLQTVRNEGFAGLYKGATPPLVGWMFMDSVMLGSLTVYRRLLRENVFSTPLPSRDPSIPVSMVADTLPAYGHGIAGVMAGSTVSFIAAPVEHVKARLQIQYASKKSDRLYAGPIDCIKKIHRHHGIPGLYHGLSATLLFRSFFFFWWGSYDLLSRWMKENTAMSAPAVNFWAGGLSAQVFWITSYPSDVVKQRIMTDPLGGGLGDGTPKFKRWRDAAVTIYREKGPMGYWRGFLPCFLRAFPANAMALVAFEGVMRSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH31</accession>
    <name>G4NH31_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor TFIID subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03956</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAF13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719908.1">
        <property type="nucleotide sequence ID" value="XM_003719860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH31"/>
    <dbReference type="SMR" id="G4NH31"/>
    <dbReference type="FunCoup" id="G4NH31">
        <property type="interactions" value="373"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NH31"/>
    <dbReference type="GeneID" id="2677339"/>
    <dbReference type="KEGG" id="mgr:MGG_03956"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03956"/>
    <dbReference type="eggNOG" id="KOG3901">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076665_1_2_1"/>
    <dbReference type="InParanoid" id="G4NH31"/>
    <dbReference type="OMA" id="QLMKDAD"/>
    <dbReference type="OrthoDB" id="10266074at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07978">
        <property type="entry name" value="HFD_TAF13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003195">
        <property type="entry name" value="TFIID_TAF13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380:SF5">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02269">
        <property type="entry name" value="TFIID-18kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="114"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="164" mass="18337" checksum="02D3C35A705121AD" modified="2011-12-14" version="1">MEPRARAGKNVGKMNFGNAELSSLLYGCGDVRQPLPETIKVMDEIATEFIQGLSFEATRVAQYSGRQKVKYQDFEFAFRRNPLHLGKVQEMFELKKQVTEARKMPGIDDDSLLKEAKQLAGETEPSTTGRGGKKRKIAAVQEEEELGEGDDDVLDEPDTVGKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH56</accession>
    <name>G4NH56_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">FRQ-interacting RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_03931</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719933.1">
        <property type="nucleotide sequence ID" value="XM_003719885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH56"/>
    <dbReference type="SMR" id="G4NH56"/>
    <dbReference type="FunCoup" id="G4NH56">
        <property type="interactions" value="1129"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NH56"/>
    <dbReference type="GeneID" id="2677161"/>
    <dbReference type="KEGG" id="mgr:MGG_03931"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03931"/>
    <dbReference type="eggNOG" id="KOG0948">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002902_0_1_1"/>
    <dbReference type="InParanoid" id="G4NH56"/>
    <dbReference type="OMA" id="IMLKNYN"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18024">
        <property type="entry name" value="DEXHc_Mtr4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13154">
        <property type="entry name" value="KOW_Mtr4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000003">
        <property type="entry name" value="ATP dependent RNA helicase (Dob1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000083">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000141">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.300:FF:000001">
        <property type="entry name" value="Mtr4 exosome RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF7">
        <property type="entry name" value="EXOSOME RNA HELICASE MTR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="185"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="420"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1102" mass="124382" checksum="06838EBB10F9004B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH64</accession>
    <name>G4NH64_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein 32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_14931</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719941.1">
        <property type="nucleotide sequence ID" value="XM_003719893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH64"/>
    <dbReference type="SMR" id="G4NH64"/>
    <dbReference type="STRING" id="242507.G4NH64"/>
    <dbReference type="GeneID" id="12987097"/>
    <dbReference type="KEGG" id="mgr:MGG_14931"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14931"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038712_1_0_1"/>
    <dbReference type="InParanoid" id="G4NH64"/>
    <dbReference type="OMA" id="SHQRGIH"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="429" mass="47546" checksum="098F6E2E50D1021B" modified="2011-12-14" version="1">MELMELVDQEPATRPFQCDWQACNKSFNRKSDLQRHYRIHTNERPYACITPGCGKSFIQRSALTVHIRTHTGEKPHQCQHIGCGKRFSDSSSLARHRRIHTGKRPYKCSHDGCAKSFCRKTTMVKHQRRSHQRGGLSSEFDECTSDSGSESPPTPRSATMSWAPAGVAMAHGLSNHALHRAQSFADFGQMNHFGLQQQYGHRQTVSQGAHEYHGQQVHHAHPDMHMVHRTAGVPTQPYYVTDQSNPGVATMNTNTVQQSYHHQVPRQQTVDGRLNLEVVTSAPSAMPSSIQSSPSSFSAGSGRSPTAQDGYYTHQAQAATYALHAAHAASTSPVEAQTPMVPYPQAMPQMSQQGHPTHAAPNVHEQFAHQAQTGAEEGWYNGVYQSPVEVTTMGQMQTYGSVAYDPWSGMKAEFEDTSLQMPSARIENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHD2</accession>
    <name>G4NHD2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_12081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720009.1">
        <property type="nucleotide sequence ID" value="XM_003719961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHD2"/>
    <dbReference type="GeneID" id="5049848"/>
    <dbReference type="KEGG" id="mgr:MGG_12081"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12081"/>
    <dbReference type="HOGENOM" id="CLU_2386606_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHD2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="94" mass="9849" checksum="8195BF5EBD759471" modified="2011-12-14" version="1">MTTLTGLVAKGCSYFPPPRLVSSGSPSVSAVAHDVAAAIEGAIIWGRSSGRADLILSSPGEAAAVMIDSQVRLLALVMRRLHLGFERGWFGPWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2024-01-24" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHT1</accession>
    <name>G4NHT1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720158.1">
        <property type="nucleotide sequence ID" value="XM_003720110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHT1"/>
    <dbReference type="GeneID" id="12987204"/>
    <dbReference type="KEGG" id="mgr:MGG_17777"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17777"/>
    <dbReference type="InParanoid" id="G4NHT1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="169" mass="19120" checksum="1BA0597891AE9723" modified="2011-12-14" version="1" fragment="single">SRSEVEASRLGAELDREDASERERLGVDELPVAGSSESEVVPDLQALGHVDLIDWDFVFPSGPVDWDAVPGFGVSSGEWCLLGSFSFLWLTCSKFQFLVVHLERFVAVLEVLDWFPSVFLMSIVFPFNQIFCFSMVSPVVEYLFDFVNSFCVDLDCFLCDSAAWCWFQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHU1</accession>
    <name>G4NHU1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CsbD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720168.1">
        <property type="nucleotide sequence ID" value="XM_003720120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHU1"/>
    <dbReference type="GeneID" id="2680330"/>
    <dbReference type="KEGG" id="mgr:MGG_09436"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09436"/>
    <dbReference type="eggNOG" id="ENOG502SD1T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_166315_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHU1"/>
    <dbReference type="OMA" id="ITGSHAW"/>
    <dbReference type="OrthoDB" id="9999611at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="10308" checksum="86E3125611F67BC5" modified="2011-12-14" version="1">MDSNTNNQTTQSQNQEPGLVAGHAEYIKGVAESAIGTVTGSQAWTASGEQDKAHAVHTMKAAGEKRDASAQGYGKVEELAGKAVGCEGMQQEGTASAKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHV4</accession>
    <name>G4NHV4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720181.1">
        <property type="nucleotide sequence ID" value="XM_003720133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHV4"/>
    <dbReference type="GeneID" id="2680401"/>
    <dbReference type="KEGG" id="mgr:MGG_09421"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09421"/>
    <dbReference type="HOGENOM" id="CLU_1315610_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHV4"/>
    <dbReference type="OrthoDB" id="10543205at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466571" evidence="2">
        <location>
            <begin position="20"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="209" mass="22568" checksum="3B1B5EC27BE203EA" modified="2011-12-14" version="1">MRPLNLFTVLAVAASGVQALAVAREVNLKLAVRAVDELHAQEPTRAKEQRHLESPQAPRIPEGGHLAERPDEAAAAAPATDHEPVLAARYLPETPTRPPGTFRKKCASTATRLGKMAHTCGNALDKLANRVGGNSGTYFSGQPSQYADPAHLQGQAYSHAMAGQQHPAPQQINVQQGYQQPAYQQPGYQNSLYPQLPPDQPVYPKPGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI60</accession>
    <name>G4NI60_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720287.1">
        <property type="nucleotide sequence ID" value="XM_003720239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI60"/>
    <dbReference type="STRING" id="242507.G4NI60"/>
    <dbReference type="GeneID" id="12987257"/>
    <dbReference type="KEGG" id="mgr:MGG_17806"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17806"/>
    <dbReference type="eggNOG" id="ENOG502T6SS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2146370_0_0_1"/>
    <dbReference type="InParanoid" id="G4NI60"/>
    <dbReference type="OMA" id="TSLICCD"/>
    <dbReference type="OrthoDB" id="5248635at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="112" mass="12138" checksum="7D8848871286A245" modified="2011-12-14" version="1">MRTWEEATWTSLICCDKAKQERLMLSVCAAKPVSSNPAPSTSSPLTVARITRLAIDNNHPPVPSSPHLLGTSSPWLQTTDSSAVWTQAPLDEEPSTAVRRTLRAPEGTGSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIP3</accession>
    <name>G4NIP3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719666.1">
        <property type="nucleotide sequence ID" value="XM_003719618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIP3"/>
    <dbReference type="GeneID" id="12986141"/>
    <dbReference type="KEGG" id="mgr:MGG_14909"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14909"/>
    <dbReference type="HOGENOM" id="CLU_2868117_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIP3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="64" mass="7163" checksum="81C483052F173E99" modified="2011-12-14" version="1">MYSLKKCTGRRNKSQARTKRLAGASYHIVLVEGSKKKPPFPVYYVAAIGKITLGRSPYPSKNYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIR6</accession>
    <name>G4NIR6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ras-like protein Rab-6A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_04143</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719687.1">
        <property type="nucleotide sequence ID" value="XM_003719639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIR6"/>
    <dbReference type="SMR" id="G4NIR6"/>
    <dbReference type="FunCoup" id="G4NIR6">
        <property type="interactions" value="460"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NIR6"/>
    <dbReference type="GeneID" id="2677653"/>
    <dbReference type="KEGG" id="mgr:MGG_04143"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04143"/>
    <dbReference type="eggNOG" id="KOG0094">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_10_2_1"/>
    <dbReference type="InParanoid" id="G4NIR6"/>
    <dbReference type="OMA" id="PVSNDGC"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01861">
        <property type="entry name" value="Rab6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000229">
        <property type="entry name" value="Probable Ras-related protein Rab-6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="209" mass="23451" checksum="23B1A54FE0207964" modified="2011-12-14" version="1">MAQSGTGAYNNPLKKFKLVFLGEQSVGKTSLITRFMYDSFDGMYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDISNAKSFQNTRKWIDDVRAERGNDVIIVLVGNKTDLNDKREVTTQQGEEEAKKNNLMFIETSAKVGHNVQPLFKRIARSLPGMEGTEAAQQAASQMIDVKTNNTQAQQEGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKL3</accession>
    <name>G4NKL3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">5'-hydroxyaverantin dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720631.1">
        <property type="nucleotide sequence ID" value="XM_003720583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKL3"/>
    <dbReference type="SMR" id="G4NKL3"/>
    <dbReference type="GeneID" id="2682603"/>
    <dbReference type="KEGG" id="mgr:MGG_03050"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03050"/>
    <dbReference type="eggNOG" id="KOG1201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_13_3_1"/>
    <dbReference type="InParanoid" id="G4NKL3"/>
    <dbReference type="OMA" id="MYTTHLA"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF16">
        <property type="entry name" value="BACILYSIN BIOSYNTHESIS OXIDOREDUCTASE BACC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA45888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="39594" checksum="E4EF8A7CD931F1CE" modified="2011-12-14" version="1">MEGLAPADMNRLVEAIKQSGPVDVSKPLKVSGLKGKTILITGGASGIGASLAREWAAHGANMIIGDINSAAGEALVAELRGSASQGQCHHFQHCNVLEWQSQVELFKAAAKASPTGGIDAVVPNAGIVDPNNPIRGKPGFENPVGLDGDRPPPPNLRVMDINCMAVFHTVHLALFWLARNKPGCDRHILLVGSIASFCPVVGESQYTASKHAVMGLFRSLRATSWRQGVRVNILCPYFIDSGLMSPVALSMMAGGRMAKMADVVHAATRLMADDQIVGRGLVVGPRIKVRDGEDGEPVVELKEPDGEPAVWDPYAHDYETVESFTRKYTRILNTIEYLRGWAGWASDMVYIFLVRKGPEKPQPTKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL33</accession>
    <name>G4NL33_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_12546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720709.1">
        <property type="nucleotide sequence ID" value="XM_003720661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL33"/>
    <dbReference type="GeneID" id="5050429"/>
    <dbReference type="KEGG" id="mgr:MGG_12546"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12546"/>
    <dbReference type="HOGENOM" id="CLU_2264277_0_0_1"/>
    <dbReference type="InParanoid" id="G4NL33"/>
    <dbReference type="OrthoDB" id="5213562at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA45966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="103" mass="11376" checksum="F60266ADE97F8D9F" modified="2011-12-14" version="1">MTVAQPVGDENTDSSPAALKLPRDVAGGWWWDQKPTGTKDRPHKCLHRPCETACKLWAVALSLGISCVFIVKNNLHQNCFFGRLHLLNINGSTFASHTFRSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHE3</accession>
    <name>G5EHE3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g807</name>
        <name evidence="3" type="ORF">MGG_03022</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720667.1">
        <property type="nucleotide sequence ID" value="XM_003720619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHE3"/>
    <dbReference type="SMR" id="G5EHE3"/>
    <dbReference type="GeneID" id="2682575"/>
    <dbReference type="KEGG" id="mgr:MGG_03022"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03022"/>
    <dbReference type="HOGENOM" id="CLU_924605_0_0_1"/>
    <dbReference type="OrthoDB" id="5210593at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="301" mass="32651" checksum="5BF9296F102DF66B" modified="2011-12-14" version="1">MENIRREVLAAYESEYRRLADVYEEKTQRMRLLNETLGYGVNHRSTGSVINTDEHRSALRRFETLAGEITDLETRVDAARAQRPSRHADDAEQPVQLTEQLLQLSDMRHRLEEAAGEFDEIMGQELQAEHDQQRMTGGAAQAAKLELSILETSTTCTAMLLQQLSDKINRWRFMSRQMAPRAGIVDRGERGGESDAQSVRSGFTRASGIGAGPAQGRSGGPFDEPGMLVADSSVFLAAMEGNGDISFDEPGVVIFSWAGRNNSPAATAAPGVHINQCQGPPGAGHGFPRGPGGSGPPDSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHL1</accession>
    <name>G5EHL1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGCH7_ch7g748</name>
        <name evidence="11" type="ORF">MGG_02970</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15</strain>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720730.1">
        <property type="nucleotide sequence ID" value="XM_003720682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHL1"/>
    <dbReference type="SMR" id="G5EHL1"/>
    <dbReference type="FunCoup" id="G5EHL1">
        <property type="interactions" value="1119"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EHL1"/>
    <dbReference type="GeneID" id="2682523"/>
    <dbReference type="KEGG" id="mgr:MGG_02970"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02970"/>
    <dbReference type="eggNOG" id="KOG1872">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017549_2_0_1"/>
    <dbReference type="OMA" id="FKSDAEY"/>
    <dbReference type="OrthoDB" id="333239at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02657">
        <property type="entry name" value="Peptidase_C19A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16104">
        <property type="entry name" value="Ubl_USP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="107"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="370"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="400"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EAQ71341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA45987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="557" mass="62255" checksum="844248F0F2C7C045" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI33</accession>
    <name>G5EI33_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g633</name>
        <name evidence="2" type="ORF">MGG_17943</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720857.1">
        <property type="nucleotide sequence ID" value="XM_003720809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI33"/>
    <dbReference type="GeneID" id="12984818"/>
    <dbReference type="KEGG" id="mgr:MGG_17943"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17943"/>
    <dbReference type="HOGENOM" id="CLU_2831674_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ71226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="66" mass="7366" checksum="E39540EF3B527830" modified="2011-12-14" version="1">MAARVLKLHDMWVPLPGNLSFLEFRLVKSRQVLGYLKYPENLSLETGQPDSLCTTVPVSAAFMGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKS6</accession>
    <name>G4MKS6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709378.1">
        <property type="nucleotide sequence ID" value="XM_003709330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKS6"/>
    <dbReference type="SMR" id="G4MKS6"/>
    <dbReference type="GeneID" id="2684845"/>
    <dbReference type="KEGG" id="mgr:MGG_06672"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06672"/>
    <dbReference type="eggNOG" id="ENOG502SZVT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119146_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKS6"/>
    <dbReference type="OMA" id="PSWPRRE"/>
    <dbReference type="OrthoDB" id="5294241at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="171" mass="19127" checksum="5FD61CEFA696FC09" modified="2011-12-14" version="1">MSAYSPYGSYSSLHTTSAPMEIGSGSFLSRPRYATMDSYNTTSFPSWPRRSSLSESEQADHPATSFLSDEDLIFDTDPFSEDDARSVSSSGSGSCSPNQPTRYDVRAEEEEARRQLQRQQKAALQRQALQMIQEEKERRRAMRQRQLQRRKSSGPSTKSKAAGAAMDPIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML84</accession>
    <name>G4ML84_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL15</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">L29</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06721</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709432.1">
        <property type="nucleotide sequence ID" value="XM_003709384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML84"/>
    <dbReference type="SMR" id="G4ML84"/>
    <dbReference type="FunCoup" id="G4ML84">
        <property type="interactions" value="984"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ML84"/>
    <dbReference type="GeneID" id="2684894"/>
    <dbReference type="KEGG" id="mgr:MGG_06721"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06721"/>
    <dbReference type="eggNOG" id="KOG1742">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109163_1_0_1"/>
    <dbReference type="InParanoid" id="G4ML84"/>
    <dbReference type="OMA" id="WGRVGQH"/>
    <dbReference type="OrthoDB" id="61900at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_uL15_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="8">
        <location>
            <begin position="72"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00080124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="150" mass="16824" checksum="F6BA9179569EF003" modified="2011-12-14" version="1">MPTRFSKTRKHRGHVSAGKGRVGKHRKHPGGRGLAGGQHHHRTNLDKYHPGYFGKVGMRHFHHLHNHDWKPIINVDKLWSLVPADKQAEYLKAGANSDKVPQIDLLSFGYSKLLGKGRLPDVPMVVRARWVSKEAEKKIKEAGGAIELVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLI3</accession>
    <name>G4MLI3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_08684</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711116.1">
        <property type="nucleotide sequence ID" value="XM_003711068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLI3"/>
    <dbReference type="GeneID" id="2678985"/>
    <dbReference type="KEGG" id="mgr:MGG_08684"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08684"/>
    <dbReference type="HOGENOM" id="CLU_1759176_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLI3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA58504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="148" mass="16446" checksum="BC62EB5F42AA396E" modified="2011-12-14" version="1">MFKNRGHLTRELKLLIRPLTCAREECFICRDNHSREATEAAAEKDGHWISTDATTLLAQRRMLLLGLVRLVVDYPQTLGQHELAYFDLALEDGFPEADIGCRNSATGHALSTSIGESTGPPSLTNLTIFNFHRPSSLPSSQLMCRGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM69</accession>
    <name>G4MM69_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_05489</name>
        <name evidence="13" type="ORF">MGG_16377</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15</strain>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 81 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710355.1">
        <property type="nucleotide sequence ID" value="XM_003710307.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710362.1">
        <property type="nucleotide sequence ID" value="XM_003710314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM69"/>
    <dbReference type="SMR" id="G4MM69"/>
    <dbReference type="STRING" id="242507.G4MM69"/>
    <dbReference type="CAZy" id="GH81">
        <property type="family name" value="Glycoside Hydrolase Family 81"/>
    </dbReference>
    <dbReference type="GeneID" id="12986295"/>
    <dbReference type="GeneID" id="2676123"/>
    <dbReference type="KEGG" id="mgr:MGG_05489"/>
    <dbReference type="KEGG" id="mgr:MGG_16377"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05489"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16377"/>
    <dbReference type="eggNOG" id="KOG2254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005482_2_1_1"/>
    <dbReference type="OMA" id="EFHEEIF"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052861">
        <property type="term" value="F:endo-1,3(4)-beta-glucanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005200">
        <property type="entry name" value="Endo-beta-glucanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040720">
        <property type="entry name" value="GH81_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040451">
        <property type="entry name" value="GH81_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983">
        <property type="entry name" value="ENDO-1,3(4)-BETA-GLUCANASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31983:SF0">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-D-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17652">
        <property type="entry name" value="Glyco_hydro81C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03639">
        <property type="entry name" value="Glyco_hydro_81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52008">
        <property type="entry name" value="GH81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007914965" description="glucan endo-1,3-beta-D-glucosidase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 N-terminal" evidence="11">
        <location>
            <begin position="74"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 81 C-terminal" evidence="12">
        <location>
            <begin position="410"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA57743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA57750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="790" mass="86344" checksum="C7E06C1440E98FF4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMC3</accession>
    <name>G4MMC3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="2681102"/>
    <dbReference type="KEGG" id="mgr:MGG_01983"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01983"/>
    <dbReference type="eggNOG" id="ENOG502TF8E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_546379_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMC3"/>
    <dbReference type="OMA" id="MQHENDA"/>
    <dbReference type="OrthoDB" id="10489217at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
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            <begin position="427"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="473"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="499" mass="55761" checksum="C4F0F069A77CAD33" modified="2011-12-14" version="1">MNLHHLQGRAAPAGPKLRGTPLKLRRDLRRAQAERDKKLDDIERDSRANVLYRPKRSRGQTQDARRRDWSSMNLELPSRPRQSAGKHVDVQGQHGQRQERLEIRLEPTSPDDRIRQRQRAPRAPVTPPPRRSPRTRSSPQHSEPSNESASDDSSSDDSSPSDTSSDDSGSDDEPSLCKRKARPRVKLSKRQQRDLLVEFVVGENDFLGALANGAKCHRDMPFWINIRKRLRLDQVTNKWSDLSRAFGVIVGTRERQAMAGKKVPCNSDVERLIDSCARIRIRRGILDGFVDDKLLNPNMVPGLIESGSLEQCELILGEMQYLQRKQRNKEVPDGPDNADEESDAQDDSELQDSNDSSDSSCDSSSSDDSNDINDDDGESTSGVSDAAHQTASSPPTSPIMASPRWPHADQASSPSSTTAATYHADTDYADNGDDEDDSSAIEEAIALLQRRQERKRRRAESGADEAPSRRVRMQHENDAMRTRGRDGADELLGRWAGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="1">DUF1996 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01986</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708726.1">
        <property type="nucleotide sequence ID" value="XM_003708678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMC8"/>
    <dbReference type="GeneID" id="2681105"/>
    <dbReference type="KEGG" id="mgr:MGG_01986"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01986"/>
    <dbReference type="eggNOG" id="ENOG502RX74">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044729_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMC8"/>
    <dbReference type="OMA" id="VMRFSAY"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018535">
        <property type="entry name" value="DUF1996"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43662:SF12">
        <property type="entry name" value="DUF1996 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09362">
        <property type="entry name" value="DUF1996"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1996" evidence="1">
        <location>
            <begin position="43"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="332" mass="36107" checksum="4C7987922E3274FC" modified="2011-12-14" version="1">MPPQMPCSSIFFSGAVAGSLFAQAALAYTVVQIPSPFMTKNIDPIVFPGAFDKSHLHSFFGADAVTATTSTTAQLQDSCTNAENPNDLSIYWVPTLLYTKDGGKTHEPVPVSRFSAYYNLGETEAQTAIPQDLKMVAGNATAKSAAEMPADAKIAWFCESEANPPPADKNGFPSKTCTTHLQHVIFFPNCVDSATLKTAYKSKSAGTANGCPEGMLSMPQLRFSIRYDLRRVLPGGWDGEAPVRQACGENVFCSHGDFINGWSKEAAENMIGTTKEKYHFAAVEGDRKKKDCKQRDADPTHGTSDFAESVKLMSKRSVETVGWTSRSRMMRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMV2</accession>
    <name>G4MMV2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB/POZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_02043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708794.1">
        <property type="nucleotide sequence ID" value="XM_003708746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMV2"/>
    <dbReference type="STRING" id="242507.G4MMV2"/>
    <dbReference type="GeneID" id="2681320"/>
    <dbReference type="KEGG" id="mgr:MGG_02043"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02043"/>
    <dbReference type="eggNOG" id="ENOG502SP2V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057752_5_3_1"/>
    <dbReference type="InParanoid" id="G4MMV2"/>
    <dbReference type="OMA" id="SICYFSE"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47843:SF5">
        <property type="entry name" value="BTB_POZ DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="34362" checksum="109C1BDF3474E9E4" modified="2011-12-14" version="1">MTPKKEPEPQPSRSEKIAVYRNQACQAVFSNPENAGLQKKKSVKSLIKKNHLSVAGFSTKRLSSILLSLQKDRVFESTSFAQAAFPELRSSEPAGAAHSAPASVPTQTQAIMEPTVRPKRELLESLERIYLTGDYSDMTIASATRNYPVHRAIEGFEGVITLHDNEPLVIDMMIQYLYLLDYKPAHDPSFQLAESKQNASAPDLLLHTKVYAIADNYAIAGLKALAVVKFKSSAGEVWNIKDFLDAAIEAYSSTVETDRDMRNAVVQMFARRKELLELDEVKNLVRKLDQLAYDLLLHFHNERRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMZ8</accession>
    <name>G4MMZ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709632.1">
        <property type="nucleotide sequence ID" value="XM_003709584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMZ8"/>
    <dbReference type="GeneID" id="12985229"/>
    <dbReference type="KEGG" id="mgr:MGG_16210"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16210"/>
    <dbReference type="HOGENOM" id="CLU_3125384_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMZ8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="50" mass="5387" checksum="B0C1F3EFB0C8D18C" modified="2011-12-14" version="1">MSKIGRTPGRLNKTKYALRPDLVSKRDTELELVPALHAAATATVWAQGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN08</accession>
    <name>G4MN08_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA polymerase</fullName>
            <ecNumber evidence="11">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_06908</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the DNA polymerase type-X family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="11"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709642.1">
        <property type="nucleotide sequence ID" value="XM_003709594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN08"/>
    <dbReference type="SMR" id="G4MN08"/>
    <dbReference type="STRING" id="242507.G4MN08"/>
    <dbReference type="GeneID" id="2685081"/>
    <dbReference type="KEGG" id="mgr:MGG_06908"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06908"/>
    <dbReference type="eggNOG" id="KOG2534">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008698_4_1_1"/>
    <dbReference type="InParanoid" id="G4MN08"/>
    <dbReference type="OMA" id="QEGWITH"/>
    <dbReference type="OrthoDB" id="205514at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.210.10:FF:000005">
        <property type="entry name" value="DNA polymerase IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000010">
        <property type="entry name" value="DNA polymerase lambda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.110:FF:000005">
        <property type="entry name" value="DNA polymerase POL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="entry name" value="DNA polymerase, thumb domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019843">
        <property type="entry name" value="DNA_pol-X_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028207">
        <property type="entry name" value="DNA_pol_B_palm_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018944">
        <property type="entry name" value="DNA_pol_lambd_fingers_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF29">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY PROTEIN POL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14792">
        <property type="entry name" value="DNA_pol_B_palm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10391">
        <property type="entry name" value="DNA_pol_lambd_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00869">
        <property type="entry name" value="DNAPOLX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81585">
        <property type="entry name" value="PsbU/PolX domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00522">
        <property type="entry name" value="DNA_POLYMERASE_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="13">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA57030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="582" mass="65410" checksum="5B0B1668DCA50EDE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNG3</accession>
    <name>G4MNG3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha</fullName>
            <ecNumber evidence="4">2.5.1.58</ecNumber>
            <ecNumber evidence="3">2.5.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">CAAX farnesyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FTase-alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ras proteins prenyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Type I protein geranyl-geranyltransferase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_16220</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="4"/>
    <dbReference type="EC" id="2.5.1.59" evidence="3"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709689.1">
        <property type="nucleotide sequence ID" value="XM_003709641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNG3"/>
    <dbReference type="SMR" id="G4MNG3"/>
    <dbReference type="FunCoup" id="G4MNG3">
        <property type="interactions" value="179"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MNG3"/>
    <dbReference type="GeneID" id="12985239"/>
    <dbReference type="KEGG" id="mgr:MGG_16220"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16220"/>
    <dbReference type="eggNOG" id="KOG0530">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026582_4_0_1"/>
    <dbReference type="InParanoid" id="G4MNG3"/>
    <dbReference type="OMA" id="PFSNKTE"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF1">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA57077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="509" mass="58023" checksum="80B8083A3BD0F37F" modified="2011-12-14" version="1">MPPKAKAAPKAKEFEKPKEAPPPPRTLNEQSHQRYELAHPLHEAFQKVGISGLSAPELQLWTSAQYCRATAASSGTAHKKQQQQLGNKAHRETWRTFNEASLPLRVPKKPTCWGKDFAGRDVGELSLDQFRARFEKRARLTCLLAARETSSPQSEPELIKEKRRRLEMATLRSELYGELVGSLARDPAWDDVVPIPLNEPDNALAAIAYPDDYAEAISYLRAVMASKEYSPRCLKLTEHIISMNPAHYTVWLYRFSIIKALGLAIPDEIQWLNSVALQHLKNYQIWHHRHLLIDNYYPKIADDKEQVARLATSERDFITTMLAEDTKNYHVWSYRQFLVRRLQAWRDPEERRAVEGLIDDDVRNNSAWSHRFFLAFTDPEQTTAGSHATEADLAVPAAVIDEELAYAKAKIDLAPQNQSPWNYLRGVLVKGGRKLASVEEFASGFVADLGDAEKEEVRSTHALDLLAEIYAEKGDKDKAALCLDRLGDEWDRIRKGYWDWRKKTLTTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP10</accession>
    <name>G4MP10_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_16443</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710571.1">
        <property type="nucleotide sequence ID" value="XM_003710523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP10"/>
    <dbReference type="SMR" id="G4MP10"/>
    <dbReference type="FunCoup" id="G4MP10">
        <property type="interactions" value="397"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MP10"/>
    <dbReference type="GeneID" id="12986381"/>
    <dbReference type="KEGG" id="mgr:MGG_16443"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16443"/>
    <dbReference type="eggNOG" id="KOG1089">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001839_5_1_1"/>
    <dbReference type="InParanoid" id="G4MP10"/>
    <dbReference type="OMA" id="RTMEGFM"/>
    <dbReference type="OrthoDB" id="271628at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004438">
        <property type="term" value="F:phosphatidylinositol-3-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030564">
        <property type="entry name" value="Myotubularin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010569">
        <property type="entry name" value="Myotubularin-like_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807">
        <property type="entry name" value="MYOTUBULARIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807:SF128">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06602">
        <property type="entry name" value="Myotub-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51339">
        <property type="entry name" value="PPASE_MYOTUBULARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myotubularin phosphatase" evidence="5">
        <location>
            <begin position="130"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="505"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="673"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="673"/>
            <end position="685"/>
        </location>
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        </location>
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        <location>
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        </location>
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    </feature>
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            <end position="809"/>
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        <location>
            <position position="409"/>
        </location>
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            <begin position="345"/>
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        </location>
        <ligand>
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        <ligand>
            <name>substrate</name>
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        <source>
            <dbReference type="ARBA" id="ARBA00007471"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA57959.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="809" mass="89282" checksum="3C1FEEABE5EBC93D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709789.1">
        <property type="nucleotide sequence ID" value="XM_003709741.1"/>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPH3</accession>
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    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <reference evidence="1 2" key="1">
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            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_003710580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPH3"/>
    <dbReference type="GeneID" id="12986391"/>
    <dbReference type="KEGG" id="mgr:MGG_16453"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16453"/>
    <dbReference type="HOGENOM" id="CLU_3143418_0_0_1"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA58016.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="49" mass="5135" checksum="37A3F3AA387E64A2" modified="2011-12-14" version="1">MDAGNDINRLCANIILFRGPNSATPTFWATMSSALILGAVRKIASKGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ77</accession>
    <name>G4MQ77_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">MGG_09252</name>
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    <organism evidence="2 3">
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709882.1">
        <property type="nucleotide sequence ID" value="XM_003709834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQ77"/>
    <dbReference type="GeneID" id="2680265"/>
    <dbReference type="KEGG" id="mgr:MGG_09252"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09252"/>
    <dbReference type="HOGENOM" id="CLU_1434690_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQ77"/>
    <dbReference type="OrthoDB" id="10638954at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465482" evidence="1">
        <location>
            <begin position="20"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="189" mass="18954" checksum="ED9A4D1C181BCD6E" modified="2011-12-14" version="1">MKFFHALTIGALAITGTVAAPVETTAVGAAIATDTVAAPIDTTTDTTAASTNITADTADTPAASIDTTGDTTDTAAAAPIDTTAVGATTITGALATPIDTIAAPIDTTAVGATTNNPTTQSNRGAFSGAGRYWGWRGNGAGTNAGSNFRGGRWPGGRIGGSGTYTNYPSRFANYGTSRRWVDRAKSLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQE6</accession>
    <name>G4MQE6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10892</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710744.1">
        <property type="nucleotide sequence ID" value="XM_003710696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQE6"/>
    <dbReference type="GeneID" id="2677039"/>
    <dbReference type="KEGG" id="mgr:MGG_10892"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10892"/>
    <dbReference type="HOGENOM" id="CLU_2015721_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQE6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465488" evidence="2">
        <location>
            <begin position="21"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="123" mass="12222" checksum="85E4AA10FAAFDA4C" modified="2011-12-14" version="1">MFGTTYAVLGSLALATLAAALPLEPRNPQAQPPANGTPGVNIPGINIPGQNGQGGFNLGPGGFTFGNPENGGGGVTWGSDGLKITPGNGNPGISVGGGQPAQPAPKPPRRVLDEQDLSVEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQP0</accession>
    <name>G4MQP0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine N-methyltransferase 2</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_09290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709939.1">
        <property type="nucleotide sequence ID" value="XM_003709891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQP0"/>
    <dbReference type="SMR" id="G4MQP0"/>
    <dbReference type="FunCoup" id="G4MQP0">
        <property type="interactions" value="378"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MQP0"/>
    <dbReference type="GeneID" id="2680168"/>
    <dbReference type="KEGG" id="mgr:MGG_09290"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09290"/>
    <dbReference type="eggNOG" id="KOG1709">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033831_0_1_1"/>
    <dbReference type="InParanoid" id="G4MQP0"/>
    <dbReference type="OMA" id="YWVVDNY"/>
    <dbReference type="OrthoDB" id="19014at2759"/>
    <dbReference type="PHI-base" id="PHI:11057"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019702">
        <property type="term" value="F:protein arginine N5-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000135">
        <property type="entry name" value="Arginine N-methyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017408">
        <property type="entry name" value="Arginine_N-MeTrfase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051038">
        <property type="entry name" value="RMT2/GAMT_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026480">
        <property type="entry name" value="RMT2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379:SF1">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038148">
        <property type="entry name" value="Arginine_N-mtfrase-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51559">
        <property type="entry name" value="SAM_RMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RMT2" evidence="10">
        <location>
            <begin position="193"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA57327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="434" mass="47312" checksum="BDAF6C98CDDDAFC5" modified="2011-12-14" version="1">MATAAPPTAPAATAPPQAQPRISPSCPEETAAILRAAAAHDAPLLKKLLDEPGKASVQDPETRETPLHAAVRAAAGTAADDTATMDLARKTLTELFWSGAIWNDVDDKDETPGCVALREGLDDLYAMCRDAGVRAEMLFGLMDGYEALSSGDSEMEQEEAVEVVDLDIENGEEAPELVDVDALKAAVVADAPTEKHTVESEAYLASKLTYNAGALVDDAGNGVMMAWETDIMRRSVDALLPELPAGKRILNVGFGMGIIDSMFAETKPSRHHIIEAHPAVIQHAKTAPDSKFGAAWEESGPEPGAFKMHQGRWQDVCRELLEAGEVYDAIYFDTFGEDYSQLRMFFTEFIPGLLDSEGRFGFFNGLGADRRICYDVYINVSEMHLAEAGLDVDWTDVPVDMDRMAEAGKGEWEGVKRRYWTLDNYRLPVCTFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR52</accession>
    <name>G4MR52_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709996.1">
        <property type="nucleotide sequence ID" value="XM_003709948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR52"/>
    <dbReference type="GeneID" id="12985313"/>
    <dbReference type="KEGG" id="mgr:MGG_16289"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16289"/>
    <dbReference type="HOGENOM" id="CLU_2979570_0_0_1"/>
    <dbReference type="InParanoid" id="G4MR52"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="58" mass="6407" checksum="4E8A586745FB2AB9" modified="2011-12-14" version="1">MCAKHANTFGTQTRIAFQKVLTGPSGTKIISWLTCRQGTEKDFPPVTRGKILVSRQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR82</accession>
    <name>G4MR82_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <ecNumber evidence="3 11">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_09926</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="3 11"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710026.1">
        <property type="nucleotide sequence ID" value="XM_003709978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR82"/>
    <dbReference type="SMR" id="G4MR82"/>
    <dbReference type="FunCoup" id="G4MR82">
        <property type="interactions" value="507"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MR82"/>
    <dbReference type="GeneID" id="2680896"/>
    <dbReference type="KEGG" id="mgr:MGG_09926"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09926"/>
    <dbReference type="eggNOG" id="KOG0563">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013524_2_3_1"/>
    <dbReference type="InParanoid" id="G4MR82"/>
    <dbReference type="OMA" id="ERAGYYE"/>
    <dbReference type="OrthoDB" id="60984at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000015">
        <property type="entry name" value="Glucose-6-phosphate 1-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000111">
        <property type="entry name" value="Glucose-6-phosphate 1-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 11" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="6 11" id="KW-0521">NADP</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="12">
        <location>
            <begin position="20"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="13">
        <location>
            <begin position="199"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA57414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="507" mass="58350" checksum="09C15E80DD306A6E" modified="2011-12-14" version="1">MAAESHAAAELELKDNTVIVVLGASGDLAKKKTYPALFGLYRNQFLPKDIKIVGYARTKMDHEEYIRRIRSYIKTPTKDMEQQLDDFCSLCTYVAGQYDKDESFYNLNDHLEDLEKNQSEAHRLFYMALPPSVFTIVSQHLKRCCYPTRGIARVIVEKPFGKDLASSRELQKSLEPDWKEDELFRIDHYLGKEMVKNILILRFGNSFLGATWNRHHIDNVQITFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQVLTLLAMERPISFSSEDIRDEKVRVLRAIPAIEPKNVIIGQYGRSLDGSKPSYKEDDTVPKESRCPTFCALVAYIKNERWDGVPFIMKAGKALNEQKTEIRIQFKDVTSGIFKDIPRNELVMRIQPNESVYIKMNSKLPGLSMQTVVTELDLTYRRRFSDLKIPEAYESLILDCLKGDHSNFVRDDELDASWRIFTPLLHYLDDNKEIVPMEYPYGSRGPAVLDDFTASYGYKFSDAAGYQWPTTSAALHANKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR94</accession>
    <name>G4MR94_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-glucanase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_13777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710831.1">
        <property type="nucleotide sequence ID" value="XM_003710783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR94"/>
    <dbReference type="SMR" id="G4MR94"/>
    <dbReference type="STRING" id="242507.G4MR94"/>
    <dbReference type="GeneID" id="5048997"/>
    <dbReference type="KEGG" id="mgr:MGG_13777"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13777"/>
    <dbReference type="eggNOG" id="ENOG502S1W9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019533_3_1_1"/>
    <dbReference type="InParanoid" id="G4MR94"/>
    <dbReference type="OMA" id="NEVQTYT"/>
    <dbReference type="OrthoDB" id="192832at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02182">
        <property type="entry name" value="GH16_Strep_laminarinase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF60">
        <property type="entry name" value="GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465244" evidence="1">
        <location>
            <begin position="19"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="36"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="282" mass="30733" checksum="E0242371474F8C35" modified="2011-12-14" version="1">MLFQTSTILALLPALAAAIRAPNKEGLKLVFEETFSGAAGASVNEDVWQIALNINSNNEHQVYTTSNENMQISGGGSFQIVPRRHADGSWTSGRIESRDAWTAPPGGVMQVESSIRLGWNLQGSKQGIWPAFWMLGDALRHGTGWPQCGEIDIMEQVSGAPTAYATVHCDVYPGGRCQEPLGRQGTTSMSDDDWHTWAVKIDRSDDDWTRQVITWTKDGAEFHRLTGDMIGDQGTWGTLAHSPLYVLLNVAVGGNWPGAPNDATLDGYGSMMEIQYVAVYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRJ2</accession>
    <name>G4MRJ2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L33-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09927</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710027.1">
        <property type="nucleotide sequence ID" value="XM_003709979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRJ2"/>
    <dbReference type="SMR" id="G4MRJ2"/>
    <dbReference type="FunCoup" id="G4MRJ2">
        <property type="interactions" value="792"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRJ2"/>
    <dbReference type="GeneID" id="2680897"/>
    <dbReference type="KEGG" id="mgr:MGG_09927"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09927"/>
    <dbReference type="eggNOG" id="KOG0887">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100745_1_0_1"/>
    <dbReference type="InParanoid" id="G4MRJ2"/>
    <dbReference type="OMA" id="YRTNKHH"/>
    <dbReference type="OrthoDB" id="1166329at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.190:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.190">
        <property type="entry name" value="translation elongation factor selb, chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00573">
        <property type="entry name" value="Ribosomal_eL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001780">
        <property type="entry name" value="Ribosomal_eL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018266">
        <property type="entry name" value="Ribosomal_eL33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038661">
        <property type="entry name" value="Ribosomal_eL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10902">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01247">
        <property type="entry name" value="Ribosomal_L35Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01105">
        <property type="entry name" value="RIBOSOMAL_L35AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="109" mass="12344" checksum="62DB54E1145048AD" modified="2011-12-14" version="1">MPTEAGHRLYVKGRHLSYQRSRHTNRPETSLIKIEGVDDTNAANFYLGKKVAYVYRAQKEVRGTKIRVIWGKVTRPHGNSGVVRAKFTTPLPTRSFGASVRIMLYPSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRX9</accession>
    <name>G4MRX9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_02466</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Vacuole membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709260.1">
        <property type="nucleotide sequence ID" value="XM_003709212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRX9"/>
    <dbReference type="SMR" id="G4MRX9"/>
    <dbReference type="FunCoup" id="G4MRX9">
        <property type="interactions" value="354"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRX9"/>
    <dbReference type="GeneID" id="2681563"/>
    <dbReference type="KEGG" id="mgr:MGG_02466"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02466"/>
    <dbReference type="eggNOG" id="KOG0232">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085752_1_2_1"/>
    <dbReference type="InParanoid" id="G4MRX9"/>
    <dbReference type="OMA" id="MGVMKPD"/>
    <dbReference type="OrthoDB" id="1744869at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:intracellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000001">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <keyword evidence="11" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="16"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="93"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA56648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="162" mass="16473" checksum="A276B8160881CAE3" modified="2011-12-14" version="1">MPSELCPAYAPFFGAMGCTAAIVFTCLGASYGTAKSGVGIAAMGVLRPDLIVKNIVPVIMAGIIGIYGLVVSVLISDNLKQDEYALFTGFIQLGAGLAVGLAGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALLMNSKATLNTTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRY7</accession>
    <name>G4MRY7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02474</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709268.1">
        <property type="nucleotide sequence ID" value="XM_003709220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRY7"/>
    <dbReference type="SMR" id="G4MRY7"/>
    <dbReference type="STRING" id="242507.G4MRY7"/>
    <dbReference type="GeneID" id="2681571"/>
    <dbReference type="KEGG" id="mgr:MGG_02474"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02474"/>
    <dbReference type="eggNOG" id="ENOG502SNWP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036929_5_0_1"/>
    <dbReference type="InParanoid" id="G4MRY7"/>
    <dbReference type="OMA" id="HEVHDVH"/>
    <dbReference type="OrthoDB" id="5305647at2759"/>
    <dbReference type="PHI-base" id="PHI:2990"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059009">
        <property type="entry name" value="Znf_C2H2_17_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF24">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26177">
        <property type="entry name" value="zf_C2H2_17_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="311"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="388" mass="43911" checksum="5C70D5939BCDAD53" modified="2011-12-14" version="1">MSVAYEPRNFIHDGSYPPIGDTHDMTDLQGVHEVHDVHESHSVHEAHEVHEHHEVHDTHDLPDVHDVHAVHELQAAQGVADVTDVTDLQDPHELHDPHNVHEVQHEVHEVHDVHDVHDVHELQADDGAQFDDADVVTELAAAVNGYHDHGPEQLMGEPEQRMVLVHGLPDVPEPPQMSPEMVVKEAESPQPTGAPRMKAIPKPARQATKNLTGKFICTWPNCNEEIREFSRKCEWNKHMDKHDRPYKCTAEGCEKLPGFTYSGGLLRHEREVHAKHGGPKNPLNCPHPTCKRHTGKGFSRQENLNEHLRRCHRNGSPSNAEGDTDDAASEAGVKRKRETEDDVAELRAEVKKQRLENDELRQKLDTQTQQIAAMMQQITDLQARDLMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSD6</accession>
    <name>G4MSD6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycoprotease family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713555.1">
        <property type="nucleotide sequence ID" value="XM_003713507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSD6"/>
    <dbReference type="STRING" id="242507.G4MSD6"/>
    <dbReference type="GeneID" id="2678157"/>
    <dbReference type="KEGG" id="mgr:MGG_04459"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04459"/>
    <dbReference type="eggNOG" id="ENOG502SB2Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004045_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSD6"/>
    <dbReference type="OMA" id="SPWDRRI"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="708"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="743"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="825"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="911"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
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        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
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        <location>
            <begin position="398"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="832"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1086"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1157" mass="125520" checksum="9FD5B3E87356E8D4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTL9</accession>
    <name>G4MTL9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein prenyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_07180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715384.1">
        <property type="nucleotide sequence ID" value="XM_003715336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTL9"/>
    <dbReference type="SMR" id="G4MTL9"/>
    <dbReference type="GeneID" id="2683163"/>
    <dbReference type="KEGG" id="mgr:MGG_07180"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07180"/>
    <dbReference type="eggNOG" id="ENOG502S6DV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044597_1_0_1"/>
    <dbReference type="InParanoid" id="G4MTL9"/>
    <dbReference type="OMA" id="MLLFDCE"/>
    <dbReference type="OrthoDB" id="5358702at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008318">
        <property type="term" value="F:protein prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF3">
        <property type="entry name" value="PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA55577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39188" checksum="30129E6C5DAEF550" modified="2011-12-14" version="1">MATAQGPISVSNLGDCNVAYQAIAAVLSHRPLAQQSGEDQAHLLEIEILGRSHPVPPGLHILQDENAVAVVKASLALAFIEARRIFLQLAQDISHHESQVLEATAVMLLFDPEHLTAANTRKRILLLQASRGGMDDFAPLLSQETWLVDSLLTSRLNRHTKSPTLWGHRRWLIGMCITTWGLPINVYDSFVKVVMVSAERHPRNYYAWGHARYLMTLHSSQSKDKKCTGLGQATRMITDAVKKWVFRHHTDTSGWSFLEHLGRTLPEKEWAAIVKETAELAMSLRWTGESVWVFLRSAIASGKSGSAGRESFAAAVEALHCTLSREPKKLETVRKAEDWIQIHEVVALDAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTR9</accession>
    <name>G4MTR9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CCCH zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_04760</name>
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    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_04760"/>
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    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
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    <dbReference type="PANTHER" id="PTHR46156">
        <property type="entry name" value="CCCH ZINGC FINGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46156:SF1">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
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            <end position="284"/>
        </location>
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        </location>
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        </location>
    </feature>
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        <location>
            <begin position="339"/>
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        </location>
    </feature>
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    </feature>
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        <location>
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        </location>
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            <begin position="22"/>
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        </location>
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            <begin position="395"/>
            <end position="452"/>
        </location>
    </feature>
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            <begin position="63"/>
            <end position="82"/>
        </location>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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</entry>
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003714558.1">
        <property type="nucleotide sequence ID" value="XM_003714510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTV7"/>
    <dbReference type="GeneID" id="5050233"/>
    <dbReference type="KEGG" id="mgr:MGG_14798"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14798"/>
    <dbReference type="eggNOG" id="ENOG502T2GE">
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    <dbReference type="InParanoid" id="G4MTV7"/>
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    <dbReference type="Proteomes" id="UP000009058">
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    <proteinExistence type="predicted"/>
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        </location>
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        <location>
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            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="275" mass="30977" checksum="18077E6F310A8A77" modified="2011-12-14" version="1">MPSVTQQEPMVCTSKKRRRGDDDGAESEENRHVYNSAVQYKIATSLPRQHHYHAADRAILVSGGQILHQDEHAHNTFFARRTLVPLQAATKRVRMDGEPTDGDHNLTRDQHRRITVAAHTRQPKVSHISSKDYQEALQQTSHNSRPHPPARSASAPAPATSTLAPCHICQRRPTKKSDLDSFADCEGCGMRTCYVCIRECLGWSRGEADSIDDESMRMEDVDDPRVFNCMGGNEHSESSRAWPRPGIWGHRQMQSLFTDTIYLSLDNGRSRLLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU90</accession>
    <name>G4MU90_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_14752</name>
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    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat mio family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713778.1">
        <property type="nucleotide sequence ID" value="XM_003713730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU90"/>
    <dbReference type="SMR" id="G4MU90"/>
    <dbReference type="FunCoup" id="G4MU90">
        <property type="interactions" value="709"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MU90"/>
    <dbReference type="GeneID" id="5049683"/>
    <dbReference type="KEGG" id="mgr:MGG_14752"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14752"/>
    <dbReference type="eggNOG" id="KOG1008">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005843_2_0_1"/>
    <dbReference type="InParanoid" id="G4MU90"/>
    <dbReference type="OMA" id="YEPTGHA"/>
    <dbReference type="OrthoDB" id="341486at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037593">
        <property type="entry name" value="MIOS/Sea4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049092">
        <property type="entry name" value="MIOS_a-sol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031488">
        <property type="entry name" value="Zn_ribbon_mio"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453:SF9">
        <property type="entry name" value="GATOR COMPLEX PROTEIN MIOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453">
        <property type="entry name" value="WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21719">
        <property type="entry name" value="MIOS_a-sol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17034">
        <property type="entry name" value="zinc_ribbon_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="MIOS-like alpha-solenoid" evidence="5">
        <location>
            <begin position="565"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="GATOR2 complex protein MIO zinc-ribbon like" evidence="4">
        <location>
            <begin position="960"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1051" mass="118040" checksum="85A47878382AA46F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUG4</accession>
    <name>G4MUG4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UBA domain-containing protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_07243</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715463.1">
        <property type="nucleotide sequence ID" value="XM_003715415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUG4"/>
    <dbReference type="SMR" id="G4MUG4"/>
    <dbReference type="GeneID" id="2683131"/>
    <dbReference type="KEGG" id="mgr:MGG_07243"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07243"/>
    <dbReference type="eggNOG" id="KOG0703">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017628_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUG4"/>
    <dbReference type="OMA" id="ASWNMGI"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000081">
        <property type="entry name" value="GTPase activating protein for Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000026">
        <property type="entry name" value="GTPase activating protein for Arf, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF7">
        <property type="entry name" value="ACTIVATING PROTEIN FOR ARF, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="4">
        <location>
            <begin position="14"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="3">
        <location>
            <begin position="210"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="522"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="560"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="560"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="604"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA55656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="676" mass="73730" checksum="D26149FF7E92CD09" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUJ0</accession>
    <name>G4MUJ0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MYG1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715489.1">
        <property type="nucleotide sequence ID" value="XM_003715441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUJ0"/>
    <dbReference type="FunCoup" id="G4MUJ0">
        <property type="interactions" value="1181"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUJ0"/>
    <dbReference type="GeneID" id="2683012"/>
    <dbReference type="KEGG" id="mgr:MGG_07266"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07266"/>
    <dbReference type="eggNOG" id="KOG2948">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051576_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUJ0"/>
    <dbReference type="OMA" id="FHCDEVV"/>
    <dbReference type="OrthoDB" id="10265310at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="METAL DEPENDENT HYDROLASE - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215:SF1">
        <property type="entry name" value="MYG1 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="377" mass="41655" checksum="60F7C5360BFFEE8F" modified="2011-12-14" version="1">MFRRLAARQFRMAESAAKRLKTEGGSSEGPVTIGTHNGHFHADEALAVYMLRQHIPTYAGASLVRTRDPAALARCHTVVDVGGEYDASTLRFDHHQRTFSTTFPGRQTKLSSAGLVYMHFGKQIIARRLADPDCDNEATVDMLYAKLYENFVEALDAHDNGISAYDPAVLATASNGQPLQKRFSDGGFTLGAVVGRLNPNWNDPIPEDPAEAQAAEDQRFEAASARIGEEFDRDLDYYTRSWLPARSVVADAFSHRAEHDPAGKGRILVFKGQSVPWKDHLYTLEQENPSAGEVVYVLYPEKPTPDAKWRIQCVPVSKDSFQSRLPLPEAWRGFRDEELDKITGIPGCVFVHAAGFIGGNKTFEGAMAMAQKALELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUM9</accession>
    <name>G4MUM9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713809.1">
        <property type="nucleotide sequence ID" value="XM_003713761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUM9"/>
    <dbReference type="SMR" id="G4MUM9"/>
    <dbReference type="GeneID" id="12987237"/>
    <dbReference type="KEGG" id="mgr:MGG_15587"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15587"/>
    <dbReference type="HOGENOM" id="CLU_2210547_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUM9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="107" mass="12144" checksum="3D18DFEDA9AF8DE3" modified="2011-12-14" version="1">MEDVPYLRKPLPVSRLRLCTKKGPWIHHGNGGWPNTCYSGGRPGTRGRKCVPWTSRRPYTGEFLIGPWWYLFAKGSCPRGKCDVLTRCTVQTHLIRTAIRAKSEVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUP4</accession>
    <name>G4MUP4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Selenoprotein W family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713824.1">
        <property type="nucleotide sequence ID" value="XM_003713776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUP4"/>
    <dbReference type="SMR" id="G4MUP4"/>
    <dbReference type="GeneID" id="2681766"/>
    <dbReference type="KEGG" id="mgr:MGG_10194"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10194"/>
    <dbReference type="eggNOG" id="ENOG502S6UH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068510_1_1_1"/>
    <dbReference type="InParanoid" id="G4MUP4"/>
    <dbReference type="OMA" id="HRLWDRK"/>
    <dbReference type="OrthoDB" id="60822at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02174">
        <property type="entry name" value="CXXU_selWTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36417:SF2">
        <property type="entry name" value="SELENOPROTEIN DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G05220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="151"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="21911" checksum="D6D8210C0AF82A51" modified="2011-12-14" version="1">MATPETNMGLSSSHLSQTTADNAIAAATETPPPLLLPRITIKFCTQCKWMLRAAYYAQELLSTFSTALGEVALQPSTGGTFVVQIQTTAAQSGGGISHRLWDRKVDGGFPETKELKRRVRDVIEPGRNLGHVDREYPRPDGAAAIPNTTAAATTTTAHHAAEHVSARASGGSTQDPLGKEDHGNGAAGSGDAEEDAVGQQKQTCEDCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUX6</accession>
    <name>G4MUX6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycogen [starch] synthase</fullName>
            <ecNumber evidence="8">2.4.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07289</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18549"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.11"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:18550"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 3 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.11" evidence="8"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715517.1">
        <property type="nucleotide sequence ID" value="XM_003715469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUX6"/>
    <dbReference type="SMR" id="G4MUX6"/>
    <dbReference type="FunCoup" id="G4MUX6">
        <property type="interactions" value="427"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUX6"/>
    <dbReference type="CAZy" id="GT3">
        <property type="family name" value="Glycosyltransferase Family 3"/>
    </dbReference>
    <dbReference type="GeneID" id="2683185"/>
    <dbReference type="KEGG" id="mgr:MGG_07289"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07289"/>
    <dbReference type="eggNOG" id="KOG3742">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015910_1_0_1"/>
    <dbReference type="InParanoid" id="G4MUX6"/>
    <dbReference type="OMA" id="RDVRNHI"/>
    <dbReference type="OrthoDB" id="6335297at2759"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="PHI-base" id="PHI:3816"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03793">
        <property type="entry name" value="GT3_GSY2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000014">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000045">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008631">
        <property type="entry name" value="Glycogen_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176:SF3">
        <property type="entry name" value="GLYCOGEN [STARCH] SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176">
        <property type="entry name" value="GLYCOGEN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05693">
        <property type="entry name" value="Glycogen_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="677"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="708" mass="80263" checksum="AE0BFA8E05A2C3C1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV50</accession>
    <name>G4MV50_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Phosphatidyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_08851</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713872.1">
        <property type="nucleotide sequence ID" value="XM_003713824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV50"/>
    <dbReference type="FunCoup" id="G4MV50">
        <property type="interactions" value="366"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MV50"/>
    <dbReference type="GeneID" id="2679837"/>
    <dbReference type="KEGG" id="mgr:MGG_08851"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08851"/>
    <dbReference type="eggNOG" id="KOG1617">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051314_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV50"/>
    <dbReference type="OMA" id="HNAQRIL"/>
    <dbReference type="OrthoDB" id="10020554at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043337">
        <property type="term" value="F:cardiolipin synthase (CMP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000017">
        <property type="entry name" value="Phosphatidyl synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA54065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="332" mass="35930" checksum="A7AB2F0D51586206" modified="2011-12-14" version="1">MPAFAMQRLSASSMALAGGRVSPSSVLLMRPMTMTTTTMATTACSHNAQRILSTLCRPASRSLLPAVSQSLLLPQRSFSITRPWLSLAKKEHKGDGQRGTTKQQPKVVGAAEPLAVTPASGKSALARENIYTIPNILTASRLVIAPFIGYCIVHDYHATALGLFAYAGVSDLLDGWIARRWNQGTVVGTIIDPMADKMLMMILTVSLAVKGALPLWLVTLIVGRDVGLACSAIYYRWVSLPPPKTFMRYWDFSLPSAEVRPTTISKYNTFLQLALMGLTTTAPVVPYDLDGALAAMHWVVAVTTVWSGASYVFSKDAVKILSQAKAVDKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV92</accession>
    <name>G4MV92_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein ypt3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_01724</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714721.1">
        <property type="nucleotide sequence ID" value="XM_003714673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV92"/>
    <dbReference type="SMR" id="G4MV92"/>
    <dbReference type="STRING" id="242507.G4MV92"/>
    <dbReference type="GeneID" id="2679780"/>
    <dbReference type="KEGG" id="mgr:MGG_01724"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01724"/>
    <dbReference type="eggNOG" id="KOG0092">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_8_0_1"/>
    <dbReference type="InParanoid" id="G4MV92"/>
    <dbReference type="OMA" id="HRYVKNA"/>
    <dbReference type="OrthoDB" id="25896at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24073">
        <property type="entry name" value="DRAB5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="346" mass="36756" checksum="D8E7C97168F4F7FE" modified="2011-12-14" version="1">MPSLEAKIVVVGSQGVGKTSLLMRYVKGSFNPSQVTSTVGASFLAKRVVADDDTVVRLQIWDTAGQERFRSISKLYYRGANACILCYSITDANSFAEMGMWLRELRRNLPADIVLHVVGTKADIVARDPSRREVPFERCIAYVAEHLAPGQTSTPPPTATPLLPTPISNGTSTPAGMAAHSTSPPFIHGGEPRSPSSKRSSGFWGMEVGWDACHEISAESGEGVEEVFRVVTRKLVEQNRKMQQALLAATATPGMTPAGDALMSGGYYDGGADHYGAGGPMSGGGPGGSAVAGYFDGMNPRGSFRVGRDRRSWLFSPAIQIEQGGAPQGGEQGAEEPDGSRRSRCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVA4</accession>
    <name>G4MVA4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C6 zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_01734</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714733.1">
        <property type="nucleotide sequence ID" value="XM_003714685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVA4"/>
    <dbReference type="GeneID" id="2679754"/>
    <dbReference type="KEGG" id="mgr:MGG_01734"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01734"/>
    <dbReference type="eggNOG" id="ENOG502QSDU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004835_4_0_1"/>
    <dbReference type="InParanoid" id="G4MVA4"/>
    <dbReference type="OMA" id="LNAECIY"/>
    <dbReference type="OrthoDB" id="4685598at2759"/>
    <dbReference type="PHI-base" id="PHI:5593"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.240.10:FF:000008">
        <property type="entry name" value="C6 zinc finger domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785:SF2">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="131"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="698" mass="76716" checksum="EF6647E85444FFBC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW29</accession>
    <name>G4MW29_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High-affinity glucose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713989.1">
        <property type="nucleotide sequence ID" value="XM_003713941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW29"/>
    <dbReference type="SMR" id="G4MW29"/>
    <dbReference type="STRING" id="242507.G4MW29"/>
    <dbReference type="GeneID" id="2679935"/>
    <dbReference type="KEGG" id="mgr:MGG_08950"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08950"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="InParanoid" id="G4MW29"/>
    <dbReference type="OMA" id="YERDPMS"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF31">
        <property type="entry name" value="HEXOSE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="464" mass="51243" checksum="FCA7A07DEC083AF8" modified="2011-12-14" version="1">MVPEFAVGKPGGPAGLHGGDGCLCWGSLIDNYGRCNGLFWSAAITMVAAGLQGGAVNIAMFCIARVIIGFGTTASVIAGSAYLAETLPWNKRAWGLCLFDDFFYVGALVASGVTYSTYKMESTWSWRLPSLLQGAWGLLCILLIPLVAESPRWLIDQGRPTEGLLVLARINANGDTRDELVRLQFCQIVETIGYERDPMSYKEMIRNRGARVRLIITATCAMFSMLTGNIVVMYNIGDMMNNVGVGDREVQLILNVGLNALSLVVSIMGSFFVDRFGVKCVTLISTGGVSISLFLLGALTRYYGNSTESAGVWAAVFAIFLFAGFYAFGWIPILFLLPAEMLYFRIRARGMAMFSFVVCATGIWGNFAFPAALVAIEWRLWIINGAWNLAFLVFIWWFWIEIRGKTLEEIDVLFDGKKHFDVPNIQEVLDGTTDDAWKKRKRGYWQITFSCSFDHPAGSIRSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX16</accession>
    <name>G4MX16_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_15645</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Cytoplasm</location>
            <location evidence="1 14">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the dynein light chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714115.1">
        <property type="nucleotide sequence ID" value="XM_003714067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX16"/>
    <dbReference type="FunCoup" id="G4MX16">
        <property type="interactions" value="650"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MX16"/>
    <dbReference type="GeneID" id="12984593"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15645"/>
    <dbReference type="eggNOG" id="KOG3430">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4MX16"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX71</accession>
    <name>G4MX71_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15803</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="893" mass="100853" checksum="8F9AE5913E884BAF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXC6</accession>
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            <fullName evidence="4">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="4" type="ORF">MGG_08255</name>
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    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003715831.1">
        <property type="nucleotide sequence ID" value="XM_003715783.1"/>
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    <dbReference type="STRING" id="242507.G4MXC6"/>
    <dbReference type="GeneID" id="2678470"/>
    <dbReference type="KEGG" id="mgr:MGG_08255"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08255"/>
    <dbReference type="eggNOG" id="KOG0379">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OMA" id="CPMLIYS"/>
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    <dbReference type="PHI-base" id="PHI:11808"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
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        <property type="term" value="P:cell redox homeostasis"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Kelch-type beta propeller"/>
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        <property type="entry name" value="Kelch-typ_b-propeller"/>
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        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
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    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF2">
        <property type="entry name" value="NEGATIVE REGULATOR OF SPORULATION MDS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
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        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="736"/>
            <end position="758"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="927"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="26"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
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        </location>
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            <end position="122"/>
        </location>
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        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
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            <begin position="170"/>
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        </location>
    </feature>
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        <location>
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            <end position="215"/>
        </location>
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        </location>
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            <end position="985"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA56024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1069" mass="114041" checksum="4044EE083C161BA4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2024-01-24" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXH1</accession>
    <name>G4MXH1_PYRO7</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_15500"/>
    <dbReference type="InParanoid" id="G4MXH1"/>
    <dbReference type="Proteomes" id="UP000009058">
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        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="80" mass="9417" checksum="674B36BC6C612C0D" modified="2011-12-14" version="1" fragment="single">SPLLFVYSQFYLVPKWSGEWWNSVTLLMQECNLKVSEWVFRKFIRGTGTFSGVRTPTSMSEMHFYLSFSAFSTGYLPRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYQ9</accession>
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        <submittedName>
            <fullName evidence="6">Pre-mRNA-processing factor 17</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">MGG_08133</name>
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    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA55288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715095.1">
        <property type="nucleotide sequence ID" value="XM_003715047.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MYQ9"/>
    <dbReference type="SMR" id="G4MYQ9"/>
    <dbReference type="FunCoup" id="G4MYQ9">
        <property type="interactions" value="844"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYQ9"/>
    <dbReference type="GeneID" id="2678328"/>
    <dbReference type="KEGG" id="mgr:MGG_08133"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08133"/>
    <dbReference type="eggNOG" id="KOG0282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022571_2_1_1"/>
    <dbReference type="InParanoid" id="G4MYQ9"/>
    <dbReference type="OMA" id="TLWHPHE"/>
    <dbReference type="OrthoDB" id="10257301at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="mRNA splicing factor"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Apc4-like_WD40_dom"/>
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    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
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        <property type="entry name" value="WD40_PAC1"/>
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        <property type="entry name" value="WD40_repeat_CS"/>
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        <property type="entry name" value="WD40_repeat_dom_sf"/>
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    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="246"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="290"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="377"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="5">
        <location>
            <begin position="439"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="509"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="31"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="87"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="542" mass="60609" checksum="E22104FF4FFC7A5C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYW7</accession>
    <name>G4MYW7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10829</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003713387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYW7"/>
    <dbReference type="STRING" id="242507.G4MYW7"/>
    <dbReference type="GeneID" id="2676344"/>
    <dbReference type="KEGG" id="mgr:MGG_10829"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10829"/>
    <dbReference type="eggNOG" id="ENOG502SA4F">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015255_1_0_1"/>
    <dbReference type="InParanoid" id="G4MYW7"/>
    <dbReference type="OMA" id="VMEAIVW"/>
    <dbReference type="OrthoDB" id="273070at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039136">
        <property type="entry name" value="NUFIP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019496">
        <property type="entry name" value="NUFIP1_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309:SF0">
        <property type="entry name" value="FMR1-INTERACTING PROTEIN NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309">
        <property type="entry name" value="NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10453">
        <property type="entry name" value="NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="470"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="470"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="542"/>
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        </location>
    </feature>
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        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="89"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="547"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="600" mass="64329" checksum="6D899531F7057A74" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZR1</accession>
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        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="5" type="ORF">MGG_07053</name>
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    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA55425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003715184.1"/>
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    <dbReference type="STRING" id="242507.G4MZR1"/>
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    <dbReference type="KEGG" id="mgr:MGG_07053"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07053"/>
    <dbReference type="eggNOG" id="KOG2383">
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    <dbReference type="HOGENOM" id="CLU_008681_7_0_1"/>
    <dbReference type="InParanoid" id="G4MZR1"/>
    <dbReference type="OMA" id="WMAKKLV"/>
    <dbReference type="OrthoDB" id="548867at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF2">
        <property type="entry name" value="AFG1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="492"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="544"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA55425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="688" mass="75971" checksum="9DE191357FBBD178" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZY7</accession>
    <name>G4MZY7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003711984.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MZY7"/>
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    <dbReference type="STRING" id="242507.G4MZY7"/>
    <dbReference type="GeneID" id="2684337"/>
    <dbReference type="KEGG" id="mgr:MGG_06153"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06153"/>
    <dbReference type="eggNOG" id="KOG2644">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030805_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZY7"/>
    <dbReference type="OMA" id="EGWAPGC"/>
    <dbReference type="OrthoDB" id="448496at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047884">
        <property type="term" value="F:FAD diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042726">
        <property type="term" value="P:flavin-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FLAD1_M"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47675">
        <property type="entry name" value="MOLYBDOPTERIN BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47675:SF1">
        <property type="entry name" value="MOLYBDOPTERIN BINDING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G11210)"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="FLAD1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="1">
        <location>
            <begin position="50"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="328" mass="36772" checksum="DF513FF2ED9E637E" modified="2011-12-14" version="1">MYSRLSLIARHISRPLPSLSQRTPIVKPRLLNFAMASADERNSRTVHTAACLIIGDEVLGGKTVDTNSNTVAKWCFELGINLKRIEVIEDDESEIIEAVRRMSDRYDFVVTSGGIGPTHDDITYQSIAKAFGLDLKLHNDAYERMKKLSRPHPSQPKFNWDEDSPAKRAKLRMVELPTDESRDMDKQFLFPREELWVPVCVVNGNVHILPGVPKLFVSLLEGLKPYIVPRLVDPEGKGICRVMISTPLAESAMAAYLTELAAKVEPQGVKVGSYPRWNKKRNTVTLVGKNKAFIESLIPEVTKNVQGRVITVEGEDDDPKDKDEPVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0F1</accession>
    <name>G4N0F1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712092.1">
        <property type="nucleotide sequence ID" value="XM_003712044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0F1"/>
    <dbReference type="SMR" id="G4N0F1"/>
    <dbReference type="STRING" id="242507.G4N0F1"/>
    <dbReference type="ESTHER" id="mago7-g4n0f1">
        <property type="family name" value="6_AlphaBeta_hydrolase"/>
    </dbReference>
    <dbReference type="GeneID" id="2684356"/>
    <dbReference type="KEGG" id="mgr:MGG_06204"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06204"/>
    <dbReference type="eggNOG" id="ENOG502QR0K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021595_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0F1"/>
    <dbReference type="OMA" id="DWYNTEH"/>
    <dbReference type="OrthoDB" id="2851338at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF31">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN YCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="296"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="539" mass="58774" checksum="F0E9E069F3EEFF21" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0L7</accession>
    <name>G4N0L7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CwfJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_07744</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712955.1">
        <property type="nucleotide sequence ID" value="XM_003712907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0L7"/>
    <dbReference type="SMR" id="G4N0L7"/>
    <dbReference type="FunCoup" id="G4N0L7">
        <property type="interactions" value="1105"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N0L7"/>
    <dbReference type="GeneID" id="2683671"/>
    <dbReference type="KEGG" id="mgr:MGG_07744"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07744"/>
    <dbReference type="eggNOG" id="KOG2476">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019955_3_0_1"/>
    <dbReference type="InParanoid" id="G4N0L7"/>
    <dbReference type="OMA" id="IVPITHY"/>
    <dbReference type="OrthoDB" id="444325at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061632">
        <property type="term" value="F:RNA lariat debranching enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="MPP_CWF19_N"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Cwf19-like"/>
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    <dbReference type="InterPro" id="IPR006767">
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        <property type="entry name" value="CWF19, CELL CYCLE CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR12072:SF4">
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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            <begin position="302"/>
            <end position="428"/>
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            <begin position="462"/>
            <end position="542"/>
        </location>
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            <begin position="257"/>
            <end position="305"/>
        </location>
    </feature>
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            <begin position="277"/>
            <end position="286"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04677"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA53148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="543" mass="60398" checksum="5226C517B1A6152F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0L9</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_07746</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="2683673"/>
    <dbReference type="KEGG" id="mgr:MGG_07746"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07746"/>
    <dbReference type="HOGENOM" id="CLU_1180430_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0L9"/>
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="1"/>
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    </feature>
    <feature type="coiled-coil region" evidence="1">
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            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA53150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="235" mass="26298" checksum="194CF74A3F8CD571" modified="2011-12-14" version="1">MPGDVQLPHAQEEMKLKEEDEERMKKKRSAPDSSVCGRKKRTWCLSDSLSDNDSDDVPPLQMKYSRRPVELKAQRRFRLRENAPPPVPPASGPKTRLPLAALQNLLAPAIKLESREVTQAREEAPPTLNGLVCGADNMAALAAKVAAEINAFRDGEARENAQLEHTVEGLKKWNTELGKMYAQLEKTNAELEKTNAELKNTNATLQNEMRELHSDAVYGRAIQGLHNRLTGRQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4N129</accession>
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        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_07794</name>
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    <organism evidence="3 4">
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713012.1">
        <property type="nucleotide sequence ID" value="XM_003712964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N129"/>
    <dbReference type="SMR" id="G4N129"/>
    <dbReference type="GeneID" id="2683721"/>
    <dbReference type="KEGG" id="mgr:MGG_07794"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07794"/>
    <dbReference type="eggNOG" id="ENOG502SUZ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_449823_0_0_1"/>
    <dbReference type="InParanoid" id="G4N129"/>
    <dbReference type="OMA" id="WDSYEAR"/>
    <dbReference type="OrthoDB" id="3477286at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF73">
        <property type="entry name" value="HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="2"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="729" mass="82093" checksum="791EF793B329AC18" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N130</accession>
    <name>G4N130_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pisatin demethylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07795</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713013.1">
        <property type="nucleotide sequence ID" value="XM_003712965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N130"/>
    <dbReference type="STRING" id="242507.G4N130"/>
    <dbReference type="GeneID" id="2683722"/>
    <dbReference type="KEGG" id="mgr:MGG_07795"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07795"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="InParanoid" id="G4N130"/>
    <dbReference type="OMA" id="YRRCVNN"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000050">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="566" mass="63781" checksum="0EA165C1FAF5542E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N158</accession>
    <name>G4N158_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711344.1">
        <property type="nucleotide sequence ID" value="XM_003711296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N158"/>
    <dbReference type="STRING" id="242507.G4N158"/>
    <dbReference type="GeneID" id="2683366"/>
    <dbReference type="KEGG" id="mgr:MGG_07446"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07446"/>
    <dbReference type="eggNOG" id="ENOG502RY95">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008869_0_0_1"/>
    <dbReference type="InParanoid" id="G4N158"/>
    <dbReference type="OMA" id="HVVHSKI"/>
    <dbReference type="OrthoDB" id="3248508at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF3">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="22"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="768" mass="84058" checksum="C06C8094D40EF708" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N173</accession>
    <name>G4N173_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711359.1">
        <property type="nucleotide sequence ID" value="XM_003711311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N173"/>
    <dbReference type="GeneID" id="12987039"/>
    <dbReference type="KEGG" id="mgr:MGG_16640"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16640"/>
    <dbReference type="HOGENOM" id="CLU_3125394_0_0_1"/>
    <dbReference type="InParanoid" id="G4N173"/>
    <dbReference type="OrthoDB" id="10369998at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="50" mass="5275" checksum="EDDBE12966FC7A19" modified="2011-12-14" version="1">MNLQRGTDAVFAMSLATMMLRATMSGRVGEPGEPGLDVQARLRGTSQAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1J0</accession>
    <name>G4N1J0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_11078</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713064.1">
        <property type="nucleotide sequence ID" value="XM_003713016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1J0"/>
    <dbReference type="SMR" id="G4N1J0"/>
    <dbReference type="STRING" id="242507.G4N1J0"/>
    <dbReference type="GeneID" id="2685194"/>
    <dbReference type="KEGG" id="mgr:MGG_11078"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11078"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_2_1"/>
    <dbReference type="InParanoid" id="G4N1J0"/>
    <dbReference type="OMA" id="SWPGANH"/>
    <dbReference type="OrthoDB" id="421993at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF67">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="168"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="640" mass="69452" checksum="3FB89A666B44F1DE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1N9</accession>
    <name>G4N1N9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Geranylgeranyl pyrophosphate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_07506</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711418.1">
        <property type="nucleotide sequence ID" value="XM_003711370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1N9"/>
    <dbReference type="SMR" id="G4N1N9"/>
    <dbReference type="STRING" id="242507.G4N1N9"/>
    <dbReference type="GeneID" id="2683426"/>
    <dbReference type="KEGG" id="mgr:MGG_07506"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07506"/>
    <dbReference type="eggNOG" id="KOG0777">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_10_0_1"/>
    <dbReference type="InParanoid" id="G4N1N9"/>
    <dbReference type="OMA" id="HITHYIG"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046165">
        <property type="term" value="P:alcohol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF72">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G01210)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA51611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="757" mass="84463" checksum="4D6E530D8644E552" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2C0</accession>
    <name>G4N2C0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712339.1">
        <property type="nucleotide sequence ID" value="XM_003712291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2C0"/>
    <dbReference type="GeneID" id="2675498"/>
    <dbReference type="KEGG" id="mgr:MGG_04859"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04859"/>
    <dbReference type="eggNOG" id="ENOG502QU2K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1619113_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2C0"/>
    <dbReference type="OMA" id="TILTAYC"/>
    <dbReference type="OrthoDB" id="4867494at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466002" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="16591" checksum="5963C9693CA46DB0" modified="2011-12-14" version="1">MIGVKAALLLLATTLGVQGQTPGNGTTPTGPHCVRGATYCGYILLHDKDYTSDQIVKAYCQGRDKCDSEGVPKDKDAWKYTLFVCLPDGKIHKHKLNRRHGNFDCTDSVDTQVVPLAYCKPPKGASGLADDDICLNPKENRIGRCWEPGNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2Z4</accession>
    <name>G4N2Z4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_13440</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711560.1">
        <property type="nucleotide sequence ID" value="XM_003711512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2Z4"/>
    <dbReference type="SMR" id="G4N2Z4"/>
    <dbReference type="STRING" id="242507.G4N2Z4"/>
    <dbReference type="GeneID" id="5050364"/>
    <dbReference type="KEGG" id="mgr:MGG_13440"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13440"/>
    <dbReference type="eggNOG" id="ENOG502QW74">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041456_5_1_1"/>
    <dbReference type="InParanoid" id="G4N2Z4"/>
    <dbReference type="OMA" id="LRKPPNH"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000020">
        <property type="entry name" value="Unplaced genomic scaffold supercont2.4, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF247">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="362"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA51753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="491" mass="54105" checksum="783CCB6D0BFE3F40" modified="2011-12-14" version="1">MSRTKQAARKNKRKAETQLQNAPTKRLTPPDDAPQAQAAVGQSHNLNAVVSSEEVEVAVDTLRTLAQHPAAIKSKACRDLRSAVYDFRQACTTGANSTGDGSMNLTARISGALVDEKYTDALVLLAEMRIRNEAPKLGALCRWVRDLDVTSGLSVKGAEAGLPPWTDRQRLLLKVLDAISRVTGTWDVKHVPVSITSDPVAIQAIWSLREEGKSWPMHQSVLDGTIFKSCATDIKEKFQVLERTPGPDRKPPNLHDAVLYLSTDNAVELSSTPPTITHHHHPAVPKLSLMKDVLSPDECRAIVGAMESVGYLPDAPVRDDGAEASILAHNVYWIVDQAFHDKLWDRVKPFVPAIADGRKVHGINRRFRVYRYVPGAEYRVHFDGAWPPSGVEPGTGKYLWDASPPENPQSSLFTFLVYLNDEFEGGETTFFTPSLREGVMNAYPVRPIMGSIALFPHGESKGALLHEGTGVRKGAKYIIRTDVEYDVNPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3H0</accession>
    <name>G4N3H0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_04956</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712452.1">
        <property type="nucleotide sequence ID" value="XM_003712404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3H0"/>
    <dbReference type="SMR" id="G4N3H0"/>
    <dbReference type="STRING" id="242507.G4N3H0"/>
    <dbReference type="GeneID" id="2675402"/>
    <dbReference type="KEGG" id="mgr:MGG_04956"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04956"/>
    <dbReference type="eggNOG" id="KOG1180">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_45_2_1"/>
    <dbReference type="InParanoid" id="G4N3H0"/>
    <dbReference type="OMA" id="HADPEHS"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="7">
        <location>
            <begin position="97"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA52645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="700" mass="75640" checksum="373EC0ACD455735F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3P8</accession>
    <name>G4N3P8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05855</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711679.1">
        <property type="nucleotide sequence ID" value="XM_003711631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3P8"/>
    <dbReference type="SMR" id="G4N3P8"/>
    <dbReference type="GeneID" id="2684120"/>
    <dbReference type="KEGG" id="mgr:MGG_05855"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05855"/>
    <dbReference type="eggNOG" id="ENOG502RY03">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013364_5_2_1"/>
    <dbReference type="InParanoid" id="G4N3P8"/>
    <dbReference type="OMA" id="GPLKCAF"/>
    <dbReference type="OrthoDB" id="425534at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF25">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="138"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S33 tripeptidyl aminopeptidase-like C-terminal" evidence="6">
        <location>
            <begin position="486"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA51872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="627" mass="69051" checksum="A184AF5490CEFA17" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3R0</accession>
    <name>G4N3R0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_05862</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711691.1">
        <property type="nucleotide sequence ID" value="XM_003711643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3R0"/>
    <dbReference type="SMR" id="G4N3R0"/>
    <dbReference type="STRING" id="242507.G4N3R0"/>
    <dbReference type="GeneID" id="2684113"/>
    <dbReference type="KEGG" id="mgr:MGG_05862"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05862"/>
    <dbReference type="eggNOG" id="ENOG502S31Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035914_2_1_1"/>
    <dbReference type="InParanoid" id="G4N3R0"/>
    <dbReference type="OMA" id="WQNEDRD"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA51884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="385" mass="43273" checksum="7F77695717DECA11" modified="2011-12-14" version="1">MRVSDVLIGSAALASAKPWGPIRWDTDPTKQFSLEKLIDLTPFDVNRFKLKSPSELLAQFNSTSRVPAPAADKADAPVPIAAPPRNSTGKVEHNADKTSAGGPCTQPAVRPEWRNMSEQGRRDYVKAAKCLVDKPSEGRFKGSHNRYEDLVWVHHQMTDQLHGFAQFLPWHRRFVNVYETALRDECGYRGPMPWWDETRDAGNFAGAPVFTPEYFGTAPVRTRDGRGGCITDGVFAGMLVHIGPGTTFEEHCLSRAVDESLTSEVSQATINQVHRQNNFESFAGLIEGWPHAYGHNGVGAVMSDVGPAPGDPIFFLHHAFIDRNWWRWQNEDRDSRVYELAGRVNNRDKRITLDYVLTMRGIQPDVTVQDVMDTYGDTLCYTYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4N408</accession>
    <name>G4N408_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_13275</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711737.1">
        <property type="nucleotide sequence ID" value="XM_003711689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N408"/>
    <dbReference type="SMR" id="G4N408"/>
    <dbReference type="GeneID" id="5049134"/>
    <dbReference type="KEGG" id="mgr:MGG_13275"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13275"/>
    <dbReference type="HOGENOM" id="CLU_706103_0_0_1"/>
    <dbReference type="InParanoid" id="G4N408"/>
    <dbReference type="OMA" id="WEDGDCC"/>
    <dbReference type="OrthoDB" id="1193027at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47849">
        <property type="entry name" value="CHITIN-BINDING LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465711" description="Chitin-binding type-1 domain-containing protein" evidence="4">
        <location>
            <begin position="18"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="5">
        <location>
            <begin position="35"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="5">
        <location>
            <begin position="94"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="5">
        <location>
            <begin position="292"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA51930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="391" mass="38326" checksum="2BF01C4F72358FD8" modified="2011-12-14" version="1">MRSTIYLQFLAPALALAQLGDNSTMTVTAGAVTVDGTCGRQNGGTVCGDFVDGNCCSMYGYCGKTTAYCGFGCQSGDCTNKPQVAPTGFTYTMDGSCGATVLCGDWEDGDCCSAAGWCGKTADYCGVGCIHGKCLGTNAPDGASATSAAPLSTGVADAAPAGPLSTGVQDQAPAPSVIPPFANTTAPADEAAAASAAAAVTETTISTVVEATPTAPVESASALPPFANTTAPDAAAPVVEPPTTATAPAPTLIVEPVNDATNATTPANTAAAAVVPTRENTPAPAGKIWAIDGFCNATALCGPWESGSCCSSYGWCGKSELHCGPGCQSGDCLTAPASASAQDAASTFATTVVAASQDAAAATQEASIMTAAPTVEATTEAAAEPTTITME</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4U9</accession>
    <name>G4N4U9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06021</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA52061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003711820.1"/>
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        <property type="interactions" value="66"/>
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    <dbReference type="KEGG" id="mgr:MGG_06021"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06021"/>
    <dbReference type="eggNOG" id="KOG2595">
        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="TBC domain protein, putative"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Rab-GAP-TBC_dom"/>
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        <property type="entry name" value="Rab-GAP_TBC_sf"/>
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        <property type="entry name" value="TBC20/Gyp8-like"/>
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        <property type="entry name" value="RE60063P"/>
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    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
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        <location>
            <begin position="79"/>
            <end position="276"/>
        </location>
    </feature>
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            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="435" mass="49323" checksum="1D6DB375E339BCEE" modified="2011-12-14" version="1">MENGSRSSAASLTASGSRESSVKSRRSISSKNSSFRLPINGDDEQILEQDMAKADAISEACKFRKINRLKELAVSRGGFLSDRLRRQAWPVLLGLEPESDEVVVDRNVSSSPVDDDGLWKEMPRHRDEDQVQLDVNRAFIYYPNIEDPIDMEHQKAELSMLIVEVLRTNPYLCYFQGYHDICQVFLLVLSPSQRAAIVARLSVLRIRDFMLPNLTPAIAQLRLLPDILQAADPSLCHHLSQTEPFFALSGTLTMYAHDVQTLGEIARLFDALLAMEPVFSVYVFAAIVMSRRAELFDTPPDEPEMLHSILSKLPQPLDLDDLLARAVLLAEDHPPETLPNWRRGISPNSVLKTARDSAVCAKQTLDQGRQFFERQVRELEWDEKREKAMAVLWAYRKPARTIGFAVAFGILAFWLRRSPGPLTYIASMSNRWLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N523</accession>
    <name>G4N523_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">DUF4211 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712741.1">
        <property type="nucleotide sequence ID" value="XM_003712693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N523"/>
    <dbReference type="STRING" id="242507.G4N523"/>
    <dbReference type="GeneID" id="2675336"/>
    <dbReference type="KEGG" id="mgr:MGG_05198"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05198"/>
    <dbReference type="eggNOG" id="ENOG502S7B9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021433_2_0_1"/>
    <dbReference type="InParanoid" id="G4N523"/>
    <dbReference type="OMA" id="WRDFHIN"/>
    <dbReference type="OrthoDB" id="21499at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025451">
        <property type="entry name" value="DUF4211"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14689:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14689">
        <property type="entry name" value="PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13926">
        <property type="entry name" value="DUF4211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4211" evidence="2">
        <location>
            <begin position="278"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="543" mass="60903" checksum="071A9C105BF8B268" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5F4</accession>
    <name>G4N5F4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
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                <person name="Shea T."/>
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                <person name="Sisk P."/>
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                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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            <strain>70-15</strain>
        </source>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_05261"/>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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        <text evidence="1">Putative transcription factor.</text>
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        </subcellularLocation>
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        <property type="entry name" value="AP-1-like"/>
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        <property type="entry name" value="bZIP"/>
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        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
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        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
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    </dbReference>
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        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="10">
        <location>
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            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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        </location>
    </feature>
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    </feature>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
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            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717016.1">
        <property type="nucleotide sequence ID" value="XM_003716968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6M8"/>
    <dbReference type="SMR" id="G4N6M8"/>
    <dbReference type="STRING" id="242507.G4N6M8"/>
    <dbReference type="GeneID" id="5049179"/>
    <dbReference type="KEGG" id="mgr:MGG_14857"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14857"/>
    <dbReference type="eggNOG" id="ENOG502ST0H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054584_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6M8"/>
    <dbReference type="OMA" id="SNLRTWA"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="349" mass="37717" checksum="0E6BDE6A897565A0" modified="2011-12-14" version="1">MLPPLEDALLQENPEFATLYNTLTTAILNPDGSSKNDPSNKEREATRQKLKAHRLNAAKQHLLVHALSTATPPPLPSASARRTTSGSRPAGASELPEPLLDLLFLLPPLLTPTPEVETLLADPTLLLTSPPLCDLPSLLPQLGDLVSASLHQAALSLARHTNPTTNPSYLHRHLPTLGPGITASHAALATAKAELSRERLAAATAVQKLLDLEAQTLGSLARTLEAKHGASARSLELRAAEVALSARQGEAEAKAALYRARRNVYSPEAGEALEAYAAHLRDSKVRVFEACRARRAELAEYGVVEGDDEDGEVEMGKKEKAMRDLAKTYHDMGRQINEVKRDLDRLDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7I7</accession>
    <name>G4N7I7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06406</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SWD2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717163.1">
        <property type="nucleotide sequence ID" value="XM_003717115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7I7"/>
    <dbReference type="SMR" id="G4N7I7"/>
    <dbReference type="FunCoup" id="G4N7I7">
        <property type="interactions" value="1011"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7I7"/>
    <dbReference type="GeneID" id="2684561"/>
    <dbReference type="KEGG" id="mgr:MGG_06406"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06406"/>
    <dbReference type="eggNOG" id="KOG1446">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044117_2_0_1"/>
    <dbReference type="InParanoid" id="G4N7I7"/>
    <dbReference type="OMA" id="HNEGYIR"/>
    <dbReference type="OrthoDB" id="27537at2759"/>
    <dbReference type="PHI-base" id="PHI:11245"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037867">
        <property type="entry name" value="Swd2/WDR82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861">
        <property type="entry name" value="WD40 REPEAT PROTEIN SWD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="135"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA50844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="373" mass="41138" checksum="2E6012315F1965C6" modified="2011-12-14" version="1">MDVDIPTVGTPTNGGASLLGSSTGGTTELQQILSTFKATRLFRRKDLRPDKPSPHVLSLDFNDPGDLCMTSESDETIQLYNVREGRHDKNLASKKYGVKLAKFTHSGTSIIYASTKQNDAIRYLETFDNSFIRYFEGHKDAVTNLEMHPGGDNFLSASRDNTVRLWDIRSKNAVGQLFLNTPYLLAWDPSGEVFAVGSPRSGSILLYDYKNYNKAPFATFDIVEACKEVDPSRLLQGWTKLEFSNDGKCILLGTDGTGHLLLDAFDGKLKANLRKPDSGTSRVAPGEGSGHGDVESSGDCCFTPDGRFVMGANRGQNVSVWDVNGAVGENKRMDPAFTLEDKREAAVLAFNPRFNFFATADRDLIFWMPDPYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8E6</accession>
    <name>G4N8E6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717313.1">
        <property type="nucleotide sequence ID" value="XM_003717265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8E6"/>
    <dbReference type="GeneID" id="12985643"/>
    <dbReference type="KEGG" id="mgr:MGG_17202"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17202"/>
    <dbReference type="HOGENOM" id="CLU_3106878_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8E6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="51" mass="5671" checksum="FA7395478AF206A4" modified="2011-12-14" version="1">MSASTSNEPGIPRGSEARLVVFKGMIFVDGKLEWINPRVNGDRTRKPVLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8I8</accession>
    <name>G4N8I8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06238</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717355.1">
        <property type="nucleotide sequence ID" value="XM_003717307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8I8"/>
    <dbReference type="GeneID" id="2684393"/>
    <dbReference type="KEGG" id="mgr:MGG_06238"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06238"/>
    <dbReference type="eggNOG" id="ENOG502SH37">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095788_1_0_1"/>
    <dbReference type="InParanoid" id="G4N8I8"/>
    <dbReference type="OMA" id="QNTAYHS"/>
    <dbReference type="OrthoDB" id="5211263at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="182"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23852" checksum="6B59FE8469349742" modified="2011-12-14" version="1">MAHHNIGEHSPFLKRVLVPFWVIRIIIMGINIASMGIAIAALAYVNSNRDRYSNELEELKSNYNVQQALSVAIVILVVQMVLVLICLAGDIACIIKRSRRTLTPKFFLGVNIFQSLFWVVSFILSMLGARTVVSIVINIVVLFSFVGLLIYASIIFHKERTGKLPSPLESHQMLGKNNVETGYYQQTSPQPQYTGTSYSPQPQYAGTTAPHANQ</sequence>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9A7</accession>
    <name>G4N9A7_PYRO7</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717467.1">
        <property type="nucleotide sequence ID" value="XM_003717419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9A7"/>
    <dbReference type="GeneID" id="12986545"/>
    <dbReference type="KEGG" id="mgr:MGG_17241"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17241"/>
    <dbReference type="HOGENOM" id="CLU_2469535_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9A7"/>
    <dbReference type="OrthoDB" id="10515121at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="88" mass="9615" checksum="A3273490AAEC0AF4" modified="2011-12-14" version="1">MENMTKIENTIPFIAPLGRELVISGAYMQALVVQQSANEFGACLVHTDVADIAQGTCPVDVDQTDLHPEYMNNGNIMSGMHPMHIAWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9X6</accession>
    <name>G4N9X6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
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    <gene>
        <name evidence="6" type="ORF">MGG_03232</name>
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    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716747.1">
        <property type="nucleotide sequence ID" value="XM_003716699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9X6"/>
    <dbReference type="SMR" id="G4N9X6"/>
    <dbReference type="STRING" id="242507.G4N9X6"/>
    <dbReference type="GeneID" id="2676742"/>
    <dbReference type="KEGG" id="mgr:MGG_03232"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03232"/>
    <dbReference type="eggNOG" id="KOG0619">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005610_0_1_1"/>
    <dbReference type="InParanoid" id="G4N9X6"/>
    <dbReference type="OMA" id="NVHRACQ"/>
    <dbReference type="OrthoDB" id="1394818at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019487">
        <property type="entry name" value="RAM_signalling_pathway_SOG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10428">
        <property type="entry name" value="SOG2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="156"/>
            <end position="231"/>
        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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        <location>
            <begin position="385"/>
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        </location>
    </feature>
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        <location>
            <begin position="401"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
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    <sequence length="1040" mass="113225" checksum="B831052B08860DC0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
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        </submittedName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA51268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAK2</accession>
    <name>G4NAK2_PYRO7</name>
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        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="7" type="ORF">MGG_09696</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003717611.1"/>
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    <dbReference type="STRING" id="242507.G4NAK2"/>
    <dbReference type="GeneID" id="2680695"/>
    <dbReference type="KEGG" id="mgr:MGG_09696"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09696"/>
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    </dbReference>
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        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
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    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="77"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="320"/>
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        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="361"/>
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        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="485"/>
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        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="525"/>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAT7</accession>
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            <fullName evidence="3">MHYT domain-containing protein</fullName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="entry name" value="MHYT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35152">
        <property type="entry name" value="DOMAIN SIGNALLING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11310)-RELATED"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR35152:SF1">
        <property type="entry name" value="DOMAIN SIGNALLING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11310)-RELATED"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF03707">
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        <source>
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB12</accession>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
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                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA48774.1"/>
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        <property type="nucleotide sequence ID" value="XM_003718310.1"/>
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    <dbReference type="GO" id="GO:0005737">
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    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
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        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0032259">
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    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
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    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
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    <dbReference type="PANTHER" id="PTHR14614:SF10">
        <property type="entry name" value="PROTEIN N-TERMINAL AND LYSINE N-METHYLTRANSFERASE EFM7"/>
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        <property type="entry name" value="Methyltransf_16"/>
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        <property type="entry name" value="SAM_MT_NNT1"/>
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    <evidence type="ECO:0000256" key="1">
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    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA48774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30351" checksum="24DA6F3BBD67A326" modified="2011-12-14" version="1">MADQKDPKPTPTHQDEEDDLSTGDMFAVPEGYYPPPPPPRTETHTLSNGAVLTLHLVGHSVMDAHHVWNGGRVLADHFLADPSLVAGKTVLEVGAGAGIPSLVAAHLGAAGVVATDYPDPEVLVALRRNVEECELVPQPRAEKVVVDGYVWGKEVEGVLAKMPGAKAAGEGVDVLIMADLLFRHTEHENIALTIERALKRSRNSRAYVFFTSYRPWLRERDLKFFDVVRDRGFVVEKVLEKKMETVMFKGDAGDEEVRKTCDGYLVTWPEDKCID</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBP9</accession>
    <name>G4NBP9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="10">dUTPase</shortName>
            <ecNumber evidence="10">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_17439</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="function">
        <text evidence="2">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>dUTP + H2O = dUMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the dUTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="10"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718541.1">
        <property type="nucleotide sequence ID" value="XM_003718493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBP9"/>
    <dbReference type="SMR" id="G4NBP9"/>
    <dbReference type="FunCoup" id="G4NBP9">
        <property type="interactions" value="1139"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NBP9"/>
    <dbReference type="GeneID" id="12984114"/>
    <dbReference type="KEGG" id="mgr:MGG_17439"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17439"/>
    <dbReference type="eggNOG" id="KOG3370">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068508_2_1_1"/>
    <dbReference type="InParanoid" id="G4NBP9"/>
    <dbReference type="OMA" id="RSGMGHK"/>
    <dbReference type="OrthoDB" id="419889at2759"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.40.10:FF:000004">
        <property type="entry name" value="Deoxyuridine triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001862">
        <property type="entry name" value="PRK00601.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241:SF0">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="dUTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase-like" evidence="12">
        <location>
            <begin position="60"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA48957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="190" mass="20078" checksum="14639DC15AFED32A" modified="2011-12-14" version="1">MNTEQPEALSAVSPPTSPPAKRVKVDTVPIMADQNTAASQPATTTIDQAPPLLIKKLSDKARLPTRGSAFAAGYDLYAAKETTIPARGKALVDTDISMAVPAGTYGRIAPRSGLAAKHFIDTGAGVIDADYRGQVKVLLFNHADADFKVEEGDRVAQLVIERIYTPEVVEVQELEESVRGAGGFGSTGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC14</accession>
    <name>G4NC14_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS phospholipid transporter Git1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_00464</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718601.1">
        <property type="nucleotide sequence ID" value="XM_003718553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC14"/>
    <dbReference type="SMR" id="G4NC14"/>
    <dbReference type="STRING" id="242507.G4NC14"/>
    <dbReference type="GeneID" id="2674367"/>
    <dbReference type="KEGG" id="mgr:MGG_00464"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00464"/>
    <dbReference type="eggNOG" id="KOG0252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_12_1"/>
    <dbReference type="InParanoid" id="G4NC14"/>
    <dbReference type="OMA" id="IMFTNFQ"/>
    <dbReference type="OrthoDB" id="2261376at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000140">
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            <end position="106"/>
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    </feature>
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        <source>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCJ0</accession>
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        <submittedName>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_01068"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        </location>
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        </location>
    </feature>
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        <source>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCL2</accession>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003718690.1">
        <property type="nucleotide sequence ID" value="XM_003718642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCL2"/>
    <dbReference type="SMR" id="G4NCL2"/>
    <dbReference type="GeneID" id="12984946"/>
    <dbReference type="KEGG" id="mgr:MGG_17466"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17466"/>
    <dbReference type="HOGENOM" id="CLU_2498294_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCL2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="86" mass="9519" checksum="D02FD27EFAEE8659" modified="2011-12-14" version="1">MVCYYAYRWESGGRDSQAMGVGSLLGCFHLICMGKPSDVFVTLMSDLATGYSAVGIAIYSTKYHYTQFLAPHYCTGTAVHVYLVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCN3</accession>
    <name>G4NCN3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718711.1">
        <property type="nucleotide sequence ID" value="XM_003718663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCN3"/>
    <dbReference type="STRING" id="242507.G4NCN3"/>
    <dbReference type="GeneID" id="12984971"/>
    <dbReference type="KEGG" id="mgr:MGG_17468"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17468"/>
    <dbReference type="HOGENOM" id="CLU_1065867_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCN3"/>
    <dbReference type="OMA" id="TELRYPY"/>
    <dbReference type="OrthoDB" id="438641at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="261" mass="28828" checksum="CD71070D2D028489" modified="2011-12-14" version="1">MLRPSRSISSLISTETLVNITLRRLEAALEDAALGSGNETTMADTNCPSEKGIFRWARALLAGPEIMKTKKRLEEQKTGIYDYRNIATMLAGGKGLYGGRGIWLIVSVLNSDRSGNCFPSLTGNMLTFRATRAKEPDTELRYPYLCSPSPGETHDERQDRFKNWGFQFGCELCVELLRTPAEAIRERNEIFLQATGQITGPTPGLEQLDEELIASYHGNDQAHYRSFLDLGVPTTTAAGRHLSVGEPLEAMAKASMVLRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND70</accession>
    <name>G4ND70_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00953</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717996.1">
        <property type="nucleotide sequence ID" value="XM_003717948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND70"/>
    <dbReference type="GeneID" id="2674466"/>
    <dbReference type="KEGG" id="mgr:MGG_00953"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00953"/>
    <dbReference type="eggNOG" id="ENOG502S24K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041456_2_1_1"/>
    <dbReference type="InParanoid" id="G4ND70"/>
    <dbReference type="OMA" id="YEDTRKC"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF241">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="7">
        <location>
            <begin position="69"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="342" mass="38760" checksum="C686A999B302B942" modified="2011-12-14" version="1">MASIPDPDLEFSDDEQQDRSFRPFKVVYNFAPVPIPDSFLSTANPPPDAQPVTLTPVDFSSVLPEYQGCHAVVLENVLSPSECVQLLRMAEASVPEADRYERRVKKKPRRSSSSSSSGKQSTDDASSSPPTAPEVFRDPWRPACVSLGANLEILDRGYRRGDRIVWDEQELTDRLWARCVQAPGLLEQLAFIGPDDPAAPFKSRYSANPPWRFSRINKRMRFLKYRRGDFFRPHCDGAYEDSSHGKQRQTLYTLHLYLNDSKVEAAMAGREPTDLVGGSTPFLSKDGSRRIDVNPRCGRVLIFQHNKLRHSGDDVVYGVKYTMRTDLLYEMVGPEEQEKRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDI7</accession>
    <name>G4NDI7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718856.1">
        <property type="nucleotide sequence ID" value="XM_003718808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDI7"/>
    <dbReference type="STRING" id="242507.G4NDI7"/>
    <dbReference type="GeneID" id="12985034"/>
    <dbReference type="KEGG" id="mgr:MGG_17492"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17492"/>
    <dbReference type="eggNOG" id="ENOG502QWIY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016622_2_0_1"/>
    <dbReference type="InParanoid" id="G4NDI7"/>
    <dbReference type="OMA" id="NQPEFYT"/>
    <dbReference type="OrthoDB" id="3365616at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22952">
        <property type="entry name" value="ART10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF166">
        <property type="entry name" value="ARRESTIN (OR S-ANTIGEN), N-TERMINAL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02050)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="572" mass="60538" checksum="98449762A3F3B99D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDP0</accession>
    <name>G4NDP0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tubulin-specific chaperone C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00899</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCC family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA48478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718062.1">
        <property type="nucleotide sequence ID" value="XM_003718014.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NDP0"/>
    <dbReference type="SMR" id="G4NDP0"/>
    <dbReference type="STRING" id="242507.G4NDP0"/>
    <dbReference type="GeneID" id="2674303"/>
    <dbReference type="KEGG" id="mgr:MGG_00899"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00899"/>
    <dbReference type="eggNOG" id="KOG2512">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032612_1_0_1"/>
    <dbReference type="InParanoid" id="G4NDP0"/>
    <dbReference type="OMA" id="YFQHEIT"/>
    <dbReference type="OrthoDB" id="194775at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.70:FF:000011">
        <property type="entry name" value="Tubulin-specific chaperone c, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1250">
        <property type="entry name" value="Tubulin Binding Cofactor C, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027684">
        <property type="entry name" value="TBCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031925">
        <property type="entry name" value="TBCC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038397">
        <property type="entry name" value="TBCC_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139">
        <property type="entry name" value="TUBULIN FOLDING COFACTOR C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16752">
        <property type="entry name" value="TBCC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="8">
        <location>
            <begin position="178"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA48478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="351" mass="38655" checksum="9450BBF926E3553B" modified="2011-12-14" version="1">MDPARFYHQVEQRVIELQDQISQLGSIATVGGERLDATEAIQADIANLTRRVADASDKLPPYDQKHYAEAIKRLTEMLNEELARLHPKPRFKFKPRTASAITSDPKNDPRLLRGTNTSGPDAEATEDVVGALPNVPGGKSYNDDISRPSGTSGIRKPSFSAARTVDIRDHEGLHIILPLTAAKATSSGSLQNMRNCVVDMSEPAAGKASFANLAIREVDRCLVVAGNVNGPAHITGVRDSVLVVSARQVRIHECRNVRMYLYCSSRPIIEDCEGMKFAPIPASHLSQDQDPTKNQWDQVDDFKWLKADHSPNWAILPEEERLSEDIWNGTVKGRPGLGPKDILRETGVLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE25</accession>
    <name>G4NE25_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00837</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718144.1">
        <property type="nucleotide sequence ID" value="XM_003718096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE25"/>
    <dbReference type="STRING" id="242507.G4NE25"/>
    <dbReference type="GeneID" id="2674627"/>
    <dbReference type="KEGG" id="mgr:MGG_00837"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00837"/>
    <dbReference type="eggNOG" id="ENOG502RYMG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023866_0_0_1"/>
    <dbReference type="InParanoid" id="G4NE25"/>
    <dbReference type="OMA" id="RLWSYRN"/>
    <dbReference type="OrthoDB" id="202545at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044:SF1">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42044">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="612" mass="66236" checksum="2B89132FF53AC1F9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEQ5</accession>
    <name>G4NEQ5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00078</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719062.1">
        <property type="nucleotide sequence ID" value="XM_003719014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEQ5"/>
    <dbReference type="GeneID" id="2675047"/>
    <dbReference type="KEGG" id="mgr:MGG_00078"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00078"/>
    <dbReference type="eggNOG" id="ENOG502SN0C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_644169_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEQ5"/>
    <dbReference type="OMA" id="HCINIAA"/>
    <dbReference type="OrthoDB" id="5283415at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="4"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA49478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="426" mass="46674" checksum="E7422EBA2A66180F" modified="2011-12-14" version="1">MVSLRIYSRTRARQIWIDDILMGLAMLLMIPMTVGSYMFTKTSFLGIHLRDVPLDQLDLSRAGRWNYIVQVFYHPILPLCKSAVLMFLLRLGGHRRPVRWAIHATNSLNLVAMAATTLTAMLQCSPVRTNWAFSASNGACNEQFEFYIAGAGIAIFTDVLVLALPFCIFLHLRISRHMKTAVLGVFLLGSIVTFVSIGRLWYFCTLYNMSMFPLPRDADLTYPITFVVSNVEANLAIICACVPALRGLARSWWPRLFRASAEVVVARDGNAVQPSPGARKTPLDTAWSVVSGSTTDRAIASRVAGDDEKLEARDVESNTSDAATCSRLLQAELRAIGTAGSTVGVCYSLSNRSNVSIAGGAERKAAEAFRDGADVGMHPLEGAIVCTTDITVQAVGDHKACLPEVARWRMRPAGVYTGPLFVMLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFI9</accession>
    <name>G4NFI9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Stress response RCI peptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08808</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719163.1">
        <property type="nucleotide sequence ID" value="XM_003719115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFI9"/>
    <dbReference type="FunCoup" id="G4NFI9">
        <property type="interactions" value="340"/>
    </dbReference>
    <dbReference type="GeneID" id="2678974"/>
    <dbReference type="KEGG" id="mgr:MGG_08808"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08808"/>
    <dbReference type="eggNOG" id="KOG1773">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107649_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFI9"/>
    <dbReference type="OMA" id="YPEPPYE"/>
    <dbReference type="OrthoDB" id="2802411at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF57">
        <property type="entry name" value="PLASMA MEMBRANE PROTEOLIPID 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="82"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA46796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="16946" checksum="274B26ABB3A8646A" modified="2011-12-14" version="1">MCSADIFLGLLAILFPPLPVWVKRGLCSADSLINILLCILGYLPGLIHSWYIIARFPEEQYEYERGYNRDAERVTYVFVAANGENQNSRGPARQPRPSANKSGAGPTYGTTNNATNNQASNSRPPQQTNAGEGGSDGAAPPSYAQVVAGDNKIQTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFR6</accession>
    <name>G4NFR6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719240.1">
        <property type="nucleotide sequence ID" value="XM_003719192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFR6"/>
    <dbReference type="SMR" id="G4NFR6"/>
    <dbReference type="FunCoup" id="G4NFR6">
        <property type="interactions" value="948"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NFR6"/>
    <dbReference type="GeneID" id="2679054"/>
    <dbReference type="KEGG" id="mgr:MGG_08745"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08745"/>
    <dbReference type="eggNOG" id="KOG1364">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021255_2_0_1"/>
    <dbReference type="InParanoid" id="G4NFR6"/>
    <dbReference type="OMA" id="PAIFDCQ"/>
    <dbReference type="OrthoDB" id="270602at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="CDD" id="cd02958">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000079">
        <property type="entry name" value="UBX domain-containing protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.300.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF6">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13899">
        <property type="entry name" value="Thioredoxin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UAS" evidence="3">
        <location>
            <begin position="245"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="420"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="420"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="571" mass="61906" checksum="671594B683FF36A1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG51</accession>
    <name>G4NG51_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_10145</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719375.1">
        <property type="nucleotide sequence ID" value="XM_003719327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG51"/>
    <dbReference type="SMR" id="G4NG51"/>
    <dbReference type="GeneID" id="2681756"/>
    <dbReference type="KEGG" id="mgr:MGG_10145"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10145"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1409039_0_0_1"/>
    <dbReference type="InParanoid" id="G4NG51"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA47008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21131" checksum="B6B5446936DC673D" modified="2011-12-14" version="1">MFKGTNKKRTITAVVAACSSMLTEMSFAANTVFLAQFNIMDSFTATMIKRAVLLLGPITVMTCIERLGRRKTFLGMDSLSASSLLMMGVLGAIQPASDGLKRGIVAVYILFTYTYIASFGSIMQIVPSEISHISLRDKTSMVYWMVSDVANFAATFLASISPFDALCRPGRQGRIHLRRHERLPPGLGVLLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG55</accession>
    <name>G4NG55_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PWI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_14969</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719379.1">
        <property type="nucleotide sequence ID" value="XM_003719331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG55"/>
    <dbReference type="SMR" id="G4NG55"/>
    <dbReference type="STRING" id="242507.G4NG55"/>
    <dbReference type="GeneID" id="12985831"/>
    <dbReference type="KEGG" id="mgr:MGG_14969"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14969"/>
    <dbReference type="eggNOG" id="KOG2253">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009938_0_0_1"/>
    <dbReference type="InParanoid" id="G4NG55"/>
    <dbReference type="OMA" id="DGCVNKK"/>
    <dbReference type="OrthoDB" id="6275295at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052768">
        <property type="entry name" value="RBM25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806">
        <property type="entry name" value="RBM25 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18806:SF4">
        <property type="entry name" value="RNA-BINDING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWI" evidence="3">
        <location>
            <begin position="726"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="403"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="589"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="456"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="589"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="819" mass="91122" checksum="521D1B1C46D088B9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGN6</accession>
    <name>G4NGN6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lambda-crystallin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_04075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719763.1">
        <property type="nucleotide sequence ID" value="XM_003719715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGN6"/>
    <dbReference type="SMR" id="G4NGN6"/>
    <dbReference type="STRING" id="242507.G4NGN6"/>
    <dbReference type="GeneID" id="2677504"/>
    <dbReference type="KEGG" id="mgr:MGG_04075"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04075"/>
    <dbReference type="eggNOG" id="KOG2305">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_0_1_1"/>
    <dbReference type="InParanoid" id="G4NGN6"/>
    <dbReference type="OMA" id="RDNCLTH"/>
    <dbReference type="OrthoDB" id="2021159at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075:SF5">
        <property type="entry name" value="3-HYDROXYBUTYRYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="3">
        <location>
            <begin position="6"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="2">
        <location>
            <begin position="190"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="330" mass="35757" checksum="54815180DF21D1D6" modified="2011-12-14" version="1">MAGVNKVAIIGCGSIGASWAALFLAQGLEVSAFDVNPSAESFLRELVANALPVLSSLGLVKSSQATAADIEFTTDMATALKNASFVQENGPERLDFKQKLFRGVANLVDPDTIIATSSSGLTCSSIQQGLEAQHKPERVVVGHPFNPPHLIPLVEVVGGEQTSQATISRTMGFYEEVGKKAVHIKKEVVGHVANRLQAALMREVMYLVQEGVADVSDIDRAMSNGPGLRWGVMGPSMLFHLGGGQGGIEYMADHLLEPMMSWYAREDPKVDDELKRKWVEGTKAAVDGREYRPLAKQRDEEIVRLLNVRKEWDGFAEACRMCSASEAGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHK5</accession>
    <name>G4NHK5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_03812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720082.1">
        <property type="nucleotide sequence ID" value="XM_003720034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHK5"/>
    <dbReference type="SMR" id="G4NHK5"/>
    <dbReference type="STRING" id="242507.G4NHK5"/>
    <dbReference type="GeneID" id="2677223"/>
    <dbReference type="KEGG" id="mgr:MGG_03812"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03812"/>
    <dbReference type="eggNOG" id="KOG0143">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010119_6_1_1"/>
    <dbReference type="InParanoid" id="G4NHK5"/>
    <dbReference type="OMA" id="RIGMEQT"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044283">
        <property type="term" value="P:small molecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="176"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="331" mass="37217" checksum="C5E289BCC6104907" modified="2011-12-14" version="1">MASVVKLDFSQFTHGSAKDRKKFGDELVKALNKSGFVKLSNHGLSDQEVEDVMQISRDFFHLPQSKKQELACPPGPNPQRGWTGPGSGEYVAKTRKENYEGLDVNKLIDAREHFDVGPEDDTQFPNRWPSDQDVPGFREKATRHYQTCRRIALQILEGIEVGLDLPGIFVNRCRTDASELCINVYPEIQAEKIDDYTKRIWPHTDYGVITLLFQDGVGGLELENQDAPGTFLPVTPTPPGESIEMVVNAADCFERWTNGFIKAGLHRVTTPCHVTEGKVVLPERCSLAYFLKATRDTMVGPLPQFVSEANPARFEEMTALEFQQLRNAVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIV2</accession>
    <name>G4NIV2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OBG-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_04106</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719725.1">
        <property type="nucleotide sequence ID" value="XM_003719677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIV2"/>
    <dbReference type="SMR" id="G4NIV2"/>
    <dbReference type="FunCoup" id="G4NIV2">
        <property type="interactions" value="41"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NIV2"/>
    <dbReference type="GeneID" id="2677616"/>
    <dbReference type="KEGG" id="mgr:MGG_04106"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04106"/>
    <dbReference type="eggNOG" id="KOG1491">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037276_1_0_1"/>
    <dbReference type="InParanoid" id="G4NIV2"/>
    <dbReference type="OMA" id="WILGNLM"/>
    <dbReference type="OrthoDB" id="545683at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04938">
        <property type="entry name" value="TGS_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01899">
        <property type="entry name" value="Ygr210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.470:FF:000001">
        <property type="entry name" value="GTP-binding protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013646">
        <property type="entry name" value="YGR210-like_G4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF1">
        <property type="entry name" value="OBG-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08438">
        <property type="entry name" value="YGR210-like_G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="5"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="417" mass="45307" checksum="D3DF801024AF828A" modified="2011-12-14" version="1">MPRDPLIGLVGKPSAGKSSTLNSLTDATSKVGNFPFTTIDPQRAIGYLQIDCACARHGLQDRCKPNHGSCVDGRRSVPIELLDVAGLVPGAHQGKGLGNKFLDDLRHADALIHVVDASGTTDAEGKNTRGYDPSVDIAWLRSEIVAWIRGNLMDKWGSIRRRHVAAKHTAVETLQAQFSGYGSTAKVVARTLDKLALKEGLEHWDDATIERVVEAFTDEKFPTVIALNKIDHPDSDKNIAKIAKMQDPNKIVLCSAISEIFLRKMAKQGYIRYTEGSEFVDTREDLVADGDPEGGGLKELDEKNKTRIENLKDMVLYRFGSTGVNQVLSKAAEVLGLVPVYPVRNTTTFGSGASESKFVFRDCVLVKKNTTVGEVARKVMGDAPVAYIEGVGAMRVSEDVVVTVGKNDILSFKVGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJD4</accession>
    <name>G4NJD4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721093.1">
        <property type="nucleotide sequence ID" value="XM_003721045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJD4"/>
    <dbReference type="GeneID" id="12984889"/>
    <dbReference type="KEGG" id="mgr:MGG_17995"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17995"/>
    <dbReference type="HOGENOM" id="CLU_2134024_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJD4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="113" mass="12418" checksum="111A85964A7C3DBB" modified="2011-12-14" version="1">MFSKAYGNPSTDVAELATTIRLTASPVVEVDQPISTRSLNTQVPFADSYHRGLGEPVEGILTPWSRGSFGLVGSPCLQMTPGQHSQPLIERRCFSDDELCLRSACHHHVCYGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJH6</accession>
    <name>G4NJH6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_18004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721135.1">
        <property type="nucleotide sequence ID" value="XM_003721087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJH6"/>
    <dbReference type="GeneID" id="12984904"/>
    <dbReference type="KEGG" id="mgr:MGG_18004"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18004"/>
    <dbReference type="HOGENOM" id="CLU_1305089_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJH6"/>
    <dbReference type="OrthoDB" id="5222300at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="211" mass="24034" checksum="6FE19FAE2B0DFD8C" modified="2011-12-14" version="1">MSTTNDFGAGGIFDEPTLEELKAVGMRQTALCKEWLEQFDLETATTRTHALAKIETWTVKEMQDREEALSKLNRLVAQSCQGREALSREEQAKVDELRELIRKDEARTFALMLQFLKDTREWSLNGLANAGRVETELEAISFAMDILDKKGLEAVNEHPRGNHVGDLFASWDQDVKMSRLGLSLCRHYESMGLPRRVPHPDMEKGRGDVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKN7</accession>
    <name>G4NKN7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_18054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721369.1">
        <property type="nucleotide sequence ID" value="XM_003721321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKN7"/>
    <dbReference type="GeneID" id="12985933"/>
    <dbReference type="KEGG" id="mgr:MGG_18054"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18054"/>
    <dbReference type="HOGENOM" id="CLU_1611104_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKN7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="165" mass="18369" checksum="A5B462493B012D6B" modified="2011-12-14" version="1">MSLPSEELADWHTRTHRTRFQTHSHSSRNQVNGQGGGLGGALGCDRRTSFGRLGSCRNVPPRFTPNGTGAAFCGAIRTRPGLGLLAVVVLWYEYLPGDFSDWIVLACSRYGTLLYGSFKVSGRKVRYGKGRNATYFGLDYAGQGYKTEEEKKGKWKRTRRNLKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH69</accession>
    <name>G5EH69_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g231</name>
        <name evidence="3" type="ORF">MGG_11096</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721290.1">
        <property type="nucleotide sequence ID" value="XM_003721242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH69"/>
    <dbReference type="SMR" id="G5EH69"/>
    <dbReference type="GeneID" id="5050549"/>
    <dbReference type="KEGG" id="mgr:MGG_11096"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11096"/>
    <dbReference type="eggNOG" id="ENOG502STSM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052827_4_1_1"/>
    <dbReference type="OMA" id="RTPCTIM"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF6">
        <property type="entry name" value="THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="105"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="201" mass="22238" checksum="3D9B55F2A888822D" modified="2011-12-14" version="1">MDPSDDNHARHPEVRYLMQTPWCAQHLASTGADDESTTPPVVRVHANRTVLPTQENQFVGGTLNSPATIAAWVNVYARPQRRLGFRIRQFVSLIALRDGMIGFPGALHGGAASLLVDEVTGMHIASQRDPDRPLNKDFRTAYLKTEYLKPIPVPGAVLVRSEIERVDGRKHWVKATIEDGSGQVLARGEVLYVALKEKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHH8</accession>
    <name>G5EHH8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGCH7_ch7g412</name>
        <name evidence="9" type="ORF">MGG_15021</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15</strain>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">70-15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721092.1">
        <property type="nucleotide sequence ID" value="XM_003721044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHH8"/>
    <dbReference type="GeneID" id="12984888"/>
    <dbReference type="KEGG" id="mgr:MGG_15021"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15021"/>
    <dbReference type="eggNOG" id="ENOG502RXA0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041955_0_0_1"/>
    <dbReference type="OMA" id="TVEGSCW"/>
    <dbReference type="OrthoDB" id="3362851at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF17">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EAQ71005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA46349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="485" mass="54183" checksum="6FD261AD01715DC7" modified="2011-12-14" version="1">MRSSRVRVVPGSCWPCKKRRVKCDLAKPVCRRCAEDGAQGQEDVRCDYNTRLIRWSTRPPVRSNNPSPATPPAVCSSVIFSPGLANDGVLSQGERRALHYFHARIWPLLQCAEAPSSPPLPFALENRVVLLTTCVLADSHRLLQEGQETEVVRRGGLGPKRAECLAEIRSRVDSCLFDKRPPMVLLFAVLLLYLHDGFIEFVTGFVSTSSHHKGVMALVGQMGGIERVLKRSEPSLQMLLAEFVSADLTTSLLHSRPPSFPASVWATVDEGAVWWNRDPLQRASLAKVFGDMSAMSFYLESIRSGQVEMSMDTVRMFERSFLPSYASPAIKLEKTSSNPPSPTSDDKSNVMTTRDDVTAVHAFALIRAFQHAALIFLYRAICRLPINHPLVQQHVQAGIQSLLEIDRKSKSLNCIIFPLYVVGAHAKLPEHRETVLDLVNLLYENMRFASVRAVMRELQNVWGSHVQDLTWQELFGGLDSNVLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHW5</accession>
    <name>G5EHW5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGCH7_ch7g282</name>
        <name evidence="4" type="ORF">MGG_02569</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyricularia</taxon>
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    </organism>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15</strain>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">70-15</strain>
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    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
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                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="5">70-15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="entry name" value="TauD/TfdA-like"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EAQ71611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KYQ30527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="409" mass="45579" checksum="4AF7E3649D947E45" modified="2006-03-07" version="1">MAPGALISEPPSAINIVTKRPSSTTTPSNNQADRSIFPDGIRTSGQHNPIYSLLRPYQDFPKSITGPTVWQKEQFEADATSWTHRFTPSEVAELGATADAFIASGVDLTGISKSNFPLPTLHRTLEALRADLLDGKGFVLFKGFPATEWGPRKTATAYMGLGTHLGYFVSQNGRGHVLGHVKDVGDDAGQIHRVRIYRTAARQFFHADDGDLVGLLCVHRAAEGGESDLVSVHAVWNELQQRHPDVAELLTRPIWYFDRKGEVSEGQEEWTRQPVFYLEPGGKGRVYCKFNPYYVRSLTRFSDKGIIPPLSEEQKRAIEILEDTCQRLALHMILEVGDIQFLSNAHILHARTAYKDFPPPAPRRHLLRLWLSTPDNEGGWVLPFPDSGEKKRGGIQVNNTPPRCPLDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2006-03-07" modified="2025-10-08" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>Q2KEP5</accession>
    <accession>A4QXE2</accession>
    <name>Q2KEP5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGCH7_ch7g991</name>
        <name evidence="5" type="ORF">MGG_10221</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15</strain>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH165218">
        <property type="protein sequence ID" value="KYQ30585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846089.1">
        <property type="nucleotide sequence ID" value="XM_016990490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q2KEP5"/>
    <dbReference type="SMR" id="Q2KEP5"/>
    <dbReference type="GeneID" id="2681872"/>
    <dbReference type="KEGG" id="mgr:MGG_10221"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10221"/>
    <dbReference type="HOGENOM" id="CLU_026673_16_5_1"/>
    <dbReference type="OMA" id="DWKRQAW"/>
    <dbReference type="OrthoDB" id="10257049at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08249">
        <property type="entry name" value="enoyl_reductase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047122">
        <property type="entry name" value="Trans-enoyl_RdTase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348">
        <property type="entry name" value="HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45348:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="14"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EAQ71584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KYQ30585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="355" mass="37415" checksum="D2C735762D8D061A" modified="2006-03-07" version="1">MSENETNVAALLPGLGQDLILQERPISSPGPGQVLIRNHSVAVNPVDWKQQAMGFMVDSYPKVLGSDIAGVIVEAGPSVDSFKPGDRVLAAAPGQTIQNNDQAAFQTFTVVPVAFVTKIPDSLSFNEAATLPVATNTASISFFDNLDLPFPSDVSAVEEQKLGSSIPGDILLVWSAGGSVGRAVVQLARVLGREVYATASPRHHEQIKKLGASLVFDYRSPTVVEDIKAAASAAGKRILVGIDNNTSADSLAGVFGVLSDGDESVRKKLLTMVPVEWVKDVVVPKDLDVSWVSGGSKTKEVETWVHTVGMPSWLERGKIAPGPYRVVPGGLGGLQAAMNELKSGVVSGEKLVVEV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-09-13" modified="2025-06-18" version="96" xmlns="https://uniprot.org/uniprot">
    <accession>Q51LA6</accession>
    <accession>A4RB73</accession>
    <accession>G4NL38</accession>
    <accession>Q2KFC2</accession>
    <name>SLU7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Pre-mRNA-splicing factor SLU7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">SLU7</name>
        <name type="ORF">MGCH7_ch7g764</name>
        <name type="ORF">MGG_02985</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SLU7 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720714.1">
        <property type="nucleotide sequence ID" value="XM_003720666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q51LA6"/>
    <dbReference type="SMR" id="Q51LA6"/>
    <dbReference type="FunCoup" id="Q51LA6">
        <property type="interactions" value="479"/>
    </dbReference>
    <dbReference type="STRING" id="242507.Q51LA6"/>
    <dbReference type="EnsemblFungi" id="MGG_02985T0">
        <property type="protein sequence ID" value="MGG_02985T0"/>
        <property type="gene ID" value="MGG_02985"/>
    </dbReference>
    <dbReference type="GeneID" id="2682538"/>
    <dbReference type="KEGG" id="mgr:MGG_02985"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02985"/>
    <dbReference type="eggNOG" id="KOG2560">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019317_3_1_1"/>
    <dbReference type="InParanoid" id="Q51LA6"/>
    <dbReference type="OMA" id="KYAWESQ"/>
    <dbReference type="OrthoDB" id="249612at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030628">
        <property type="term" value="F:pre-mRNA 3'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021715">
        <property type="entry name" value="Slu7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039974">
        <property type="entry name" value="Splicing_factor_SLU7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942">
        <property type="entry name" value="STEP II SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11708">
        <property type="entry name" value="Slu7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0508">mRNA splicing</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0747">Spliceosome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_0000218550" description="Pre-mRNA-splicing factor SLU7">
        <location>
            <begin position="1"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CCHC-type">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="410"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="474" mass="53683" checksum="D0561A12FF94BCB3" modified="2005-06-07" version="1">MPPPPPPPRRPALGAAGASKEENVYIPNFISKRPFYAVDEGENTDYLEHQRIQKKEKDTGWYDRGKTLGPAATKYRKGACENCGAMTHKVKDCLSRPRAKGAKWTGRDIKADELVQDVRMGWDAKRDRWNGYDAREYQAVVEDYNKMEELRKEMQAKAAAESGKAIEDGDHYAETSDMSKHQPTSTRQLRLREDTAKYLLNLDLDSAKYDPKTRTIVDAGATNDKTAELYAEQGFLRQSGDAAEFEKAQRYAWEAQEKGGDTSLHLQANPTAGSYMRKKLKEEEDAKREERERQLREKYGGEETKVLPDAIRQMAVTESERYVEYDEIGLIKGGPKGVARSKYKEDIFHNNHTSVWGSWWSDFKWGYACCHSFVKNSYCTGEEGKAAWEAAERQRTGSGLLEPAADAEVDGAREEERKASEAETAAAAKEKAKKRTAEQMIGDVTEAELDEYRRKRTNTDDPMAQLLGRDELVT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-08-30" modified="2025-06-18" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>Q51TF7</accession>
    <accession>A4QSC1</accession>
    <accession>G4ML32</accession>
    <name>CWC2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Pre-mRNA-splicing factor CWC2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">CWC2</name>
        <name type="ORF">MGG_08641</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The C-terminal RRM domain and the zinc finger motif are necessary for RNA-binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RRM CWC2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711071.1">
        <property type="nucleotide sequence ID" value="XM_003711023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q51TF7"/>
    <dbReference type="SMR" id="Q51TF7"/>
    <dbReference type="FunCoup" id="Q51TF7">
        <property type="interactions" value="164"/>
    </dbReference>
    <dbReference type="STRING" id="242507.Q51TF7"/>
    <dbReference type="EnsemblFungi" id="MGG_08641T0">
        <property type="protein sequence ID" value="MGG_08641T0"/>
        <property type="gene ID" value="MGG_08641"/>
    </dbReference>
    <dbReference type="GeneID" id="2678873"/>
    <dbReference type="KEGG" id="mgr:MGG_08641"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08641"/>
    <dbReference type="eggNOG" id="KOG0118">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043308_1_0_1"/>
    <dbReference type="InParanoid" id="Q51TF7"/>
    <dbReference type="OMA" id="CNIAKDS"/>
    <dbReference type="OrthoDB" id="10251848at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045787">
        <property type="term" value="P:positive regulation of cell cycle"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033120">
        <property type="term" value="P:positive regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="CDD" id="cd12360">
        <property type="entry name" value="RRM_cwf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000249">
        <property type="entry name" value="Pre-mRNA-splicing factor CWC2, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034181">
        <property type="entry name" value="Cwc2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032297">
        <property type="entry name" value="Torus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16131">
        <property type="entry name" value="Torus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0508">mRNA splicing</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0747">Spliceosome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_0000081548" description="Pre-mRNA-splicing factor CWC2">
        <location>
            <begin position="1"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="167"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="3">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="394" mass="43256" checksum="DB6537C336686420" modified="2007-06-12" version="2">MSDTEQPQAAEGTELVPTSNGPVVPEGQKKVKKIIRVKKKRPARPQIDPALVKSEPPPQTGTTFNIWYNKWSGGDREDKYTSQTAAKGRCNVAKDSGYTKADQTTGSYFCLFFARGVCPKGQDCEYLHRLPTLHDLYSPNVDCFGRDRFSDYRDDMGGVGSFMRQNRTVYVGRIHVTDDIEEVVARHFAEWGQVERIRVLNQRGVAFITYTNEANAQFAKEAMAHQSLDHNEILNVRWATADPNPMAQAREARRVEEQAAEAVRRALPAEFVAEIEGRDPEARKRRKMESSYGLDGYEAPDEVHFARGAQAVNPVGRRGFEDQLMLEGGGEEVSAREALFGAEGSGSGDGDAGGIFSSSTLAALNSAQVKVSAQPKQAAATGPLVAYGSDSEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4K3</accession>
    <name>A0A151V4K3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_10273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165178">
        <property type="protein sequence ID" value="KYQ30509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846013.1">
        <property type="nucleotide sequence ID" value="XM_016990519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4K3"/>
    <dbReference type="SMR" id="A0A151V4K3"/>
    <dbReference type="GeneID" id="2681818"/>
    <dbReference type="KEGG" id="mgr:MGG_10273"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10273"/>
    <dbReference type="eggNOG" id="ENOG502SJ3Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4K3"/>
    <dbReference type="OMA" id="HIPYFEE"/>
    <dbReference type="OrthoDB" id="10039566at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF2">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KYQ30509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="399" mass="42726" checksum="83B32B7354B58C38" modified="2016-06-08" version="1">MIGLVIFLAIFLPVLLTSMKSFLVIIPAIIQRLMNEASLPINGGTLALHSPDELKVSIKTTVAMPAGIVASLDPITLQLYNSNTTAFSPFMAVDLPKQHLDGPTDIDAPESIVRISNKTELTSWLRYVVRDPTVDLSLRGDSHINLGAIRSAVHLEKTTPVRALNHLRGFGVPSIRLVVPPEPDGANVRGQLLFPNHTPLHLGLGNLTFNMWSGPVRLGTVDVHDVLAAPGDNLFDFRGVLLLRDLLPNLGAILASQASALGRGSIVLGVSGNSTVVNGRHVAFFEEVLNGERFETELSVVSVAMQVLGGLIDPAASNGTSALLDTVSAVLGNKTLIDGIVDKLNASRVVDRLNSTADPVAIPGNLLKRVQRELTRTALKSVVRELRGGRSKPLWSPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A4QYZ4</accession>
    <name>A4QYZ4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713041.1">
        <property type="nucleotide sequence ID" value="XM_003712993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4QYZ4"/>
    <dbReference type="GeneID" id="12985951"/>
    <dbReference type="KEGG" id="mgr:MGG_15254"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15254"/>
    <dbReference type="HOGENOM" id="CLU_2776422_0_0_1"/>
    <dbReference type="InParanoid" id="A4QYZ4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="69" mass="7437" checksum="D2E0DEDC63A06E39" modified="2007-05-15" version="1">MENLSETAWYYIDIRPSWPAFTSLVVTLQQAGKPPLGFAAEGVGGSSRVNAVLPGFYSPGGPRIDRLRA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-07-01" modified="2026-01-28" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4R1D5</accession>
    <accession>G4MNU2</accession>
    <name>YME2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Mitochondrial escape protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">YME2</name>
        <name type="ORF">MGG_06965</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the YME2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709711.1">
        <property type="nucleotide sequence ID" value="XM_003709663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R1D5"/>
    <dbReference type="FunCoup" id="A4R1D5">
        <property type="interactions" value="113"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_06965T0">
        <property type="protein sequence ID" value="MGG_06965T0"/>
        <property type="gene ID" value="MGG_06965"/>
    </dbReference>
    <dbReference type="GeneID" id="2685138"/>
    <dbReference type="KEGG" id="mgr:MGG_06965"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06965"/>
    <dbReference type="eggNOG" id="ENOG502QS0P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007861_0_0_1"/>
    <dbReference type="InParanoid" id="A4R1D5"/>
    <dbReference type="OMA" id="WTPEQAW"/>
    <dbReference type="OrthoDB" id="10267654at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12433">
        <property type="entry name" value="RRM_Yme2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018850">
        <property type="entry name" value="Mt_escape_2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039627">
        <property type="entry name" value="Yme2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034260">
        <property type="entry name" value="Yme2_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32198">
        <property type="entry name" value="MITOCHONDRIAL ESCAPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32198:SF2">
        <property type="entry name" value="MITOCHONDRIAL ESCAPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10443">
        <property type="entry name" value="RNA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0809">Transit peptide</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="transit peptide" description="Mitochondrion" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000343125" description="Mitochondrial escape protein 2">
        <location>
            <begin position="60"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial matrix" evidence="2">
        <location>
            <begin position="60"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="topological domain" description="Mitochondrial intermembrane" evidence="2">
        <location>
            <begin position="354"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="226"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="644"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="644"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="901" mass="100022" checksum="37A72AAD98FCB71B" modified="2012-01-25" version="2" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MK91</accession>
    <name>G4MK91_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709294.1">
        <property type="nucleotide sequence ID" value="XM_003709246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MK91"/>
    <dbReference type="GeneID" id="12984429"/>
    <dbReference type="KEGG" id="mgr:MGG_16132"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16132"/>
    <dbReference type="HOGENOM" id="CLU_3069169_0_0_1"/>
    <dbReference type="InParanoid" id="G4MK91"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013356845" evidence="1">
        <location>
            <begin position="16"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="53" mass="5836" checksum="77FB8BA759ABBBF9" modified="2011-12-14" version="1">MKLLCLQLGLGFVFAADPSVMLPSDGQLPVFTLPYAAYRATNYSSIGDIRRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKD1</accession>
    <name>G4MKD1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Vacuolar protein sorting-associated protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_02524</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the VPS29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709334.1">
        <property type="nucleotide sequence ID" value="XM_003709286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKD1"/>
    <dbReference type="SMR" id="G4MKD1"/>
    <dbReference type="FunCoup" id="G4MKD1">
        <property type="interactions" value="1062"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKD1"/>
    <dbReference type="GeneID" id="2681621"/>
    <dbReference type="KEGG" id="mgr:MGG_02524"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02524"/>
    <dbReference type="eggNOG" id="KOG3325">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063749_0_1_1"/>
    <dbReference type="InParanoid" id="G4MKD1"/>
    <dbReference type="OMA" id="VRGNMDY"/>
    <dbReference type="OrthoDB" id="10258130at2759"/>
    <dbReference type="PHI-base" id="PHI:11144"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07394">
        <property type="entry name" value="MPP_Vps29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000024">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028661">
        <property type="entry name" value="Vps29"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN VPS29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="6">
        <location>
            <begin position="4"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA56722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="202" mass="22216" checksum="E62D282FE64C8EE3" modified="2011-12-14" version="1">MAFLILVIGDLHIPDRALDIPPKFKKLLAPGKIGQTLCLGNLTDRTTYEYLRSVAPDLKIVKGRLDVEATSLPLSQVVTHGSIRIGFLEGFTLVSNEPDLLLAEANKLDVDVLCWGGTHRFECFEYMDKFFINPGSATGAFTTGWGTEEDIVPSFCLMDVQGISLTLYVYQLRKDENGVENVAVEKVTYTKVVEPPTTASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKJ1</accession>
    <name>G4MKJ1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Inositol phosphosphingolipids phospholipase C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_04474</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the neutral sphingomyelinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710986.1">
        <property type="nucleotide sequence ID" value="XM_003710938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKJ1"/>
    <dbReference type="SMR" id="G4MKJ1"/>
    <dbReference type="FunCoup" id="G4MKJ1">
        <property type="interactions" value="70"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKJ1"/>
    <dbReference type="GeneID" id="2677807"/>
    <dbReference type="KEGG" id="mgr:MGG_04474"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04474"/>
    <dbReference type="eggNOG" id="KOG3873">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034001_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKJ1"/>
    <dbReference type="OMA" id="IEESSMF"/>
    <dbReference type="OrthoDB" id="387657at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF24">
        <property type="entry name" value="PHOSPHODIESTERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="535"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="561"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="15">
        <location>
            <begin position="11"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="365"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="449"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="369"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA58374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="651" mass="72059" checksum="04E5D69CA9EA821D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKJ7</accession>
    <name>G4MKJ7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome P450 97B3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_04469</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
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        <property type="protein sequence ID" value="EHA58380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710992.1">
        <property type="nucleotide sequence ID" value="XM_003710944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKJ7"/>
    <dbReference type="SMR" id="G4MKJ7"/>
    <dbReference type="FunCoup" id="G4MKJ7">
        <property type="interactions" value="1471"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKJ7"/>
    <dbReference type="GeneID" id="2677796"/>
    <dbReference type="KEGG" id="mgr:MGG_04469"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04469"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_11_1"/>
    <dbReference type="InParanoid" id="G4MKJ7"/>
    <dbReference type="OMA" id="WKHQRRT"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="CYP_FUM15-like"/>
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    </dbReference>
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        <property type="entry name" value="Cytochrome P450 monooxygenase (Fum15)"/>
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    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
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        <property type="entry name" value="Cyt_P450_E_grp-I"/>
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    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF227">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="200"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="493"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA58380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="602" mass="66922" checksum="A3F0E0971DE70D22" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKQ5</accession>
    <name>G4MKQ5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Potassium channel tetramerisation-type BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709357.1">
        <property type="nucleotide sequence ID" value="XM_003709309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKQ5"/>
    <dbReference type="SMR" id="G4MKQ5"/>
    <dbReference type="FunCoup" id="G4MKQ5">
        <property type="interactions" value="33"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKQ5"/>
    <dbReference type="GeneID" id="2684824"/>
    <dbReference type="KEGG" id="mgr:MGG_06651"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06651"/>
    <dbReference type="eggNOG" id="ENOG502QRM9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017395_0_1_1"/>
    <dbReference type="InParanoid" id="G4MKQ5"/>
    <dbReference type="OMA" id="PHEKVFP"/>
    <dbReference type="OrthoDB" id="2414723at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051260">
        <property type="term" value="P:protein homooligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003131">
        <property type="entry name" value="T1-type_BTB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31758">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN YLR108C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31758:SF2">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN YLR108C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02214">
        <property type="entry name" value="BTB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Potassium channel tetramerisation-type BTB" evidence="1">
        <location>
            <begin position="54"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="493" mass="55386" checksum="2C7AFE3507552F7E" modified="2011-12-14" version="1">MFSEDRNSIPAAFMAADRGDSAAHHSGPAGELKRDLKLMSKIPRILPHERVFPIQIGSKLFKLSGASLSSDAPSYFSQYFLCQMKAAEENGDDVCSSIRTLYIDRDPMTFQDIALHLQGYHVHPRDATHFVRLFADAQFYSLPKLISQLYEEPIFMTIGHREFQIPRDLFKDPGNSPNFFTLGFAIFFSSPDDLFPGLDRRDLIRPPSILPPSVPHRSADTFEEILHLLRGNPVNVRDETHRQTLLRDVRYFNFKGLEQRLISHCASYNQLRARHQILLRVEDIYKSGISVYPEPPSAVDSAPSHGWVNYARPYLGDKPAELVLQIGGNASRVGPLEIILRDDFAPLPDSTVYTAQLEFFLDAKKRVARLFDVVGSLLKVSVVQADQLVAIIDKDAAITLDGKPFTGHRDADDLADIDVDALTVGTDGPARKRRKTVASRQRPGIETAGWVIRTGQWRLRTRCLHGTLECLFVAVKLEAFSSEHSSNSMAEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKZ5</accession>
    <name>G4MKZ5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711034.1">
        <property type="nucleotide sequence ID" value="XM_003710986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKZ5"/>
    <dbReference type="GeneID" id="2678901"/>
    <dbReference type="KEGG" id="mgr:MGG_08607"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08607"/>
    <dbReference type="HOGENOM" id="CLU_1896637_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKZ5"/>
    <dbReference type="OrthoDB" id="10500877at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465765" evidence="1">
        <location>
            <begin position="23"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="134" mass="15084" checksum="AFED819ABE2E2A3C" modified="2011-12-14" version="1">MRFDSFFSASLVSLAFVMGGAAAMPSDTTGKPSGTTVDPSKPDYSAPRYWIDKCIVQLLDATTEEIVMERFSSGFGMWDSVSYLGHTYQFRLDQDCKTIWGDSRGSIHPSVKFRKVRARVNMHTRKLDPLYVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLA3</accession>
    <name>G4MLA3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tim10-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710245.1">
        <property type="nucleotide sequence ID" value="XM_003710197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLA3"/>
    <dbReference type="GeneID" id="2676176"/>
    <dbReference type="KEGG" id="mgr:MGG_05389"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05389"/>
    <dbReference type="HOGENOM" id="CLU_2171561_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLA3"/>
    <dbReference type="OMA" id="FEVICYD"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465185" description="Tim10-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12359" checksum="F83E00D7FFE9F161" modified="2011-12-14" version="1">MRPQFIIAGVFALVANASAMEASDAKLRPRADIDLSPMNNLMTYDQCRDSCVSGFERSGGVPRNFEVICYDKCLHLLKEQAKFATANYQAALKFPGPRMNTEKRQELGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLF3</accession>
    <name>G4MLF3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chromatin assembly factor 1 subunit A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08654</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711086.1">
        <property type="nucleotide sequence ID" value="XM_003711038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLF3"/>
    <dbReference type="SMR" id="G4MLF3"/>
    <dbReference type="STRING" id="242507.G4MLF3"/>
    <dbReference type="GeneID" id="2678880"/>
    <dbReference type="KEGG" id="mgr:MGG_08654"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08654"/>
    <dbReference type="eggNOG" id="KOG4364">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013392_3_0_1"/>
    <dbReference type="InParanoid" id="G4MLF3"/>
    <dbReference type="OMA" id="YENVRPP"/>
    <dbReference type="OrthoDB" id="79480at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033186">
        <property type="term" value="C:CAF-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048800">
        <property type="entry name" value="Cac1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022043">
        <property type="entry name" value="CAF1A_DD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272:SF0">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21796">
        <property type="entry name" value="Cac1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12253">
        <property type="entry name" value="CAF1A_dimeriz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromatin assembly factor 1 subunit A dimerization" evidence="6">
        <location>
            <begin position="363"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Chromatin assembly factor 1 subunit Cac1-like C-terminal" evidence="7">
        <location>
            <begin position="564"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="423"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="117"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA58474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="621" mass="68776" checksum="880BDD34FA3EB412" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLS6</accession>
    <name>G4MLS6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710316.1">
        <property type="nucleotide sequence ID" value="XM_003710268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLS6"/>
    <dbReference type="GeneID" id="12986280"/>
    <dbReference type="KEGG" id="mgr:MGG_16364"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16364"/>
    <dbReference type="eggNOG" id="ENOG502T4E9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_130533_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLS6"/>
    <dbReference type="OMA" id="VYCADAP"/>
    <dbReference type="OrthoDB" id="5149687at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="178" mass="19025" checksum="35FC8D10104FA92A" modified="2011-12-14" version="1">MCHQINYTLPCEHVRTHTVYCPDATKSKSSSSSSSSSSNSNKHSSSKSSSKSASKSSYGKSGGKSSASSASSSSSKKPCKNLTQQSLPYPTPPSFAGSPMTAASSPLVPKCPLESCPFEAKNRCWNCCWCGKEWNEAGRCSCIMIIEGNHVQTSGARNRQPNRGREVGQMQVSRSISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM47</accession>
    <name>G4MM47_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06828</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709544.1">
        <property type="nucleotide sequence ID" value="XM_003709496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM47"/>
    <dbReference type="SMR" id="G4MM47"/>
    <dbReference type="GeneID" id="2685001"/>
    <dbReference type="KEGG" id="mgr:MGG_06828"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06828"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="InParanoid" id="G4MM47"/>
    <dbReference type="OMA" id="WVICIGM"/>
    <dbReference type="OrthoDB" id="9971669at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17327">
        <property type="entry name" value="MFS_FEN2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000018">
        <property type="entry name" value="MFS transporter permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF53">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="47"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="496" mass="55512" checksum="D0A2A64A279027C2" modified="2011-12-14" version="1">MEQSEKTEAQYVDRQGDLSRSDSDGVDGLSWTKEEEDKLRHKIDWHCVPIVTVLYLLCFLDRINIGNARIQGLATELDLNRGVRFNWVLSIFYIIYLFVEVPSNIILKKVGPRFYLPFLVVGFGFVSMCTAFVHSYEGLLAARAFLGVFEGGAMPGMAFFLSCFYKRGELLFRIGIYVSAASMAGAFGGLLAAGLAQIPEWGIASMRIYAWRNIFFFEGLLTVIIGLLAPIWMPTDPATAYFLNERERRIAAERLAREHKSHPDERVSWAHVKRAMLCIHNYTCALGFFLINITVQGLSVFMPTILADFNYDPIKAQLMSVPPYVCACLGAIAIAYLSDKTKQRGLYLAIFAVIAMIGFAILRWHQDSDIKYMAIYFVTIGAFPGGPAFLAWAINNSAGPSVRAVSSAYVVTLGTIGGIVSTWTYIKEDGPRYPNGHTVNLAGQIGVFFLAIFGILYCLRENKLRAAGKRDHRLEGLTEDETLHLGYRHPSFRYIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMG9</accession>
    <name>G4MMG9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alkaline foam protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709559.1">
        <property type="nucleotide sequence ID" value="XM_003709511.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MMG9"/>
    <dbReference type="SMR" id="G4MMG9"/>
    <dbReference type="GeneID" id="12984553"/>
    <dbReference type="KEGG" id="mgr:MGG_16187"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16187"/>
    <dbReference type="eggNOG" id="ENOG502SP7Z">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144311_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMG9"/>
    <dbReference type="OMA" id="ANDAGCY"/>
    <dbReference type="OrthoDB" id="3682664at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006771">
        <property type="entry name" value="CetA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36195:SF4">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01990)-RELATED"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR36195">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04681">
        <property type="entry name" value="Bys1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465269" description="Alkaline foam protein B" evidence="1">
        <location>
            <begin position="19"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="16252" checksum="FC89D125AAEB649E" modified="2011-12-14" version="1">MKFTSTVAAIALVVGASAQQAIVHNNCQDTVYVQSFPYDGSATGPLTTLQAGQTFSEDFRKSGSTVKVSKTKTLTSPLFIGYSFSSNPDYGYYELSSEWGNPFADKRVTLSPGAGCQDFNCAPNDAGCYSRPDMKKVYGCPLPINVEATLCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMQ7</accession>
    <name>G4MMQ7_PYRO7</name>
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        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_13119</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710441.1">
        <property type="nucleotide sequence ID" value="XM_003710393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMQ7"/>
    <dbReference type="SMR" id="G4MMQ7"/>
    <dbReference type="GeneID" id="5051520"/>
    <dbReference type="KEGG" id="mgr:MGG_13119"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13119"/>
    <dbReference type="eggNOG" id="ENOG502RA4K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030426_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMQ7"/>
    <dbReference type="OMA" id="TYIVAWH"/>
    <dbReference type="OrthoDB" id="3543857at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="488"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="499"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="59497" checksum="490D53C20EB06827" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNV5</accession>
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    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06975</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709724.1">
        <property type="nucleotide sequence ID" value="XM_003709676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNV5"/>
    <dbReference type="SMR" id="G4MNV5"/>
    <dbReference type="GeneID" id="2685148"/>
    <dbReference type="KEGG" id="mgr:MGG_06975"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06975"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_324668_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNV5"/>
    <dbReference type="OMA" id="QSRYDGM"/>
    <dbReference type="OrthoDB" id="366390at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="177"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="734"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="889" mass="99942" checksum="0EDB3C25B06C52C3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPV6</accession>
    <name>G4MPV6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709865.1">
        <property type="nucleotide sequence ID" value="XM_003709817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPV6"/>
    <dbReference type="GeneID" id="12985276"/>
    <dbReference type="KEGG" id="mgr:MGG_16254"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16254"/>
    <dbReference type="HOGENOM" id="CLU_2942218_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPV6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="60" mass="6342" checksum="C568112EB29EA3A7" modified="2011-12-14" version="1">MNRMQLATLLAIRAGSYCQKESMSGQETTLKGHSYQGGFGTTVATSVTENRGSMEPGSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPX1</accession>
    <name>G4MPX1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710671.1">
        <property type="nucleotide sequence ID" value="XM_003710623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPX1"/>
    <dbReference type="SMR" id="G4MPX1"/>
    <dbReference type="GeneID" id="2676155"/>
    <dbReference type="KEGG" id="mgr:MGG_05752"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05752"/>
    <dbReference type="eggNOG" id="ENOG502S5A2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136352_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPX1"/>
    <dbReference type="OMA" id="VAKKPMG"/>
    <dbReference type="OrthoDB" id="5331396at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37849">
        <property type="entry name" value="YALI0E11605P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37849:SF1">
        <property type="entry name" value="YALI0E11605P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="113" mass="12646" checksum="F3A8EA834F796FF3" modified="2011-12-14" version="1">MSSRLFSVGARVLGHTSPLTRSFQTTTRRFDAVSNATLPARKPVGAFRGGLFGFLFGTTLAGSGVYYYVLQEYKAANDLLTEDIYNLQASVQRLSNYLTTLEDRIEATERRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ76</accession>
    <name>G4MQ76_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tat pathway signal sequence</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_09251</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ustYa family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709881.1">
        <property type="nucleotide sequence ID" value="XM_003709833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQ76"/>
    <dbReference type="STRING" id="242507.G4MQ76"/>
    <dbReference type="GeneID" id="2680264"/>
    <dbReference type="KEGG" id="mgr:MGG_09251"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09251"/>
    <dbReference type="eggNOG" id="ENOG502SI30">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042941_0_1_1"/>
    <dbReference type="InParanoid" id="G4MQ76"/>
    <dbReference type="OMA" id="NVEGFHH"/>
    <dbReference type="OrthoDB" id="3687641at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021765">
        <property type="entry name" value="UstYa-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365:SF13">
        <property type="entry name" value="TAT PATHWAY SIGNAL SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33365">
        <property type="entry name" value="YALI0B05434P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11807">
        <property type="entry name" value="UstYa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0843">Virulence</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA57269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="33887" checksum="C14E1106C54DEAF3" modified="2011-12-14" version="1">METPKSPRKEVYRPLTGHSDDRRFSVEDELFDYQNHSDSQPQRRYHHHRNYILWALYMASNVISFVVGGYFGTKMHDSSLNRECSVHTSAYSPLMKDVDIKYAYTSFNGSFLKETVYRRDASPEVDAAWEALGVDYRPGVIPLQDGPASGLEERHVQRSEKYGAGYFVNVEGMHHLHCLNLVRKSLYFNYAYYKDLGMHAFKNDDHILKLHTTHCLDTIRQVLMCNVDTGLLGQVWYDPQKPAAFPDFNTQHKCKNFDAVRQWAETLQAPPADQIPMDYLKPADPRYILPSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQW4</accession>
    <name>G4MQW4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Alkaline protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_04733</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710807.1">
        <property type="nucleotide sequence ID" value="XM_003710759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQW4"/>
    <dbReference type="SMR" id="G4MQW4"/>
    <dbReference type="GeneID" id="2677817"/>
    <dbReference type="KEGG" id="mgr:MGG_04733"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04733"/>
    <dbReference type="eggNOG" id="KOG1153">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003559_2_1_1"/>
    <dbReference type="InParanoid" id="G4MQW4"/>
    <dbReference type="OMA" id="HAVHWAT"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465390" evidence="9">
        <location>
            <begin position="20"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="134"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="11">
        <location>
            <begin position="456"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA58195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="723" mass="76864" checksum="619F4B8AE6A407C6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR22</accession>
    <name>G4MR22_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable transporter MCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_11919</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709169.1">
        <property type="nucleotide sequence ID" value="XM_003709121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR22"/>
    <dbReference type="FunCoup" id="G4MR22">
        <property type="interactions" value="16"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MR22"/>
    <dbReference type="GeneID" id="5049710"/>
    <dbReference type="KEGG" id="mgr:MGG_11919"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11919"/>
    <dbReference type="eggNOG" id="ENOG502S0C9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012596_2_0_1"/>
    <dbReference type="InParanoid" id="G4MR22"/>
    <dbReference type="OMA" id="PTMWWLA"/>
    <dbReference type="OrthoDB" id="199930at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17354">
        <property type="entry name" value="MFS_Mch1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF45">
        <property type="entry name" value="TRANSPORTER MCH1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="520"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="549"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="584"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="625"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA56557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="660" mass="69455" checksum="B5EC69855AD5C176" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR32</accession>
    <name>G4MR32_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Maintenance of ploidy protein mob2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709976.1">
        <property type="nucleotide sequence ID" value="XM_003709928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR32"/>
    <dbReference type="SMR" id="G4MR32"/>
    <dbReference type="STRING" id="242507.G4MR32"/>
    <dbReference type="GeneID" id="2680947"/>
    <dbReference type="KEGG" id="mgr:MGG_09882"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09882"/>
    <dbReference type="eggNOG" id="KOG0440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038321_0_1_1"/>
    <dbReference type="InParanoid" id="G4MR32"/>
    <dbReference type="OMA" id="VSYAHNP"/>
    <dbReference type="OrthoDB" id="10261121at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="11"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="38548" checksum="49D7483204A7F071" modified="2011-12-14" version="1">MSNLFSGINARFRGGTNKPAIQTKSPPNLGSGPASPTALSASQSSSSLASKLPPLPNSPSLAQTLGMDENSGIMATGEDILNSYHLPRPLPLWLNPGYARHIVKGNFMTLSARPKTVEQGEWIAHQVVEHYRNLWNFVRVVHEKEEDGTTICNSTTCPRTSAGANHSFTWLNSRREPVELPAHEYMTLMQRWISGKIDDTNIFPTEASGVSFAHNPQYCPPALSQLAGPGGEGGDWVGKRSGFPENFVEVCKTIFRQMFRVYAHLYWAHFVEPFYHLNLEKQLNSCFSHFVLTATALDMLKPHELEPMQPLIDLWAANGTFPQGSRAYEYANLRAGEKLMQLGGMSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRG1</accession>
    <name>G4MRG1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709200.1">
        <property type="nucleotide sequence ID" value="XM_003709152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRG1"/>
    <dbReference type="GeneID" id="12984402"/>
    <dbReference type="KEGG" id="mgr:MGG_16122"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16122"/>
    <dbReference type="HOGENOM" id="CLU_2776410_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRG1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="69" mass="7721" checksum="A7E71F45981FBF1E" modified="2011-12-14" version="1">MHADMQDFFSLALFSFFFLFFYGLYIQEGPYGAGAGGAAYELWLFGNMAVPSRQDYYAGTGDIRVPIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRH7</accession>
    <name>G4MRH7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">6-O-methylguanine-DNA methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_02429</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="3"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709216.1">
        <property type="nucleotide sequence ID" value="XM_003709168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRH7"/>
    <dbReference type="SMR" id="G4MRH7"/>
    <dbReference type="STRING" id="242507.G4MRH7"/>
    <dbReference type="GeneID" id="2681526"/>
    <dbReference type="KEGG" id="mgr:MGG_02429"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02429"/>
    <dbReference type="eggNOG" id="ENOG502S8GR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_52_3_1"/>
    <dbReference type="InParanoid" id="G4MRH7"/>
    <dbReference type="OMA" id="GGYKGSW"/>
    <dbReference type="OrthoDB" id="1907495at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10815:SF13">
        <property type="entry name" value="METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="Methylated DNA-protein cysteine methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding" evidence="12">
        <location>
            <begin position="15"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA56604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="132" mass="14350" checksum="E8275009C52C5973" modified="2011-12-14" version="1">MQPQLDLIAASSRTAFEKKVWSLLCQIPSGSVSTYGIMSAHLGSSPRAVGNALRRNPFAPEVPCHRVVATGGALGGFKGKWPRDGEGITLDEKRLLLRREGVRFDDAGARILGTPFSGFRPHMQYIDSPNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRQ3</accession>
    <name>G4MRQ3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_04623</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710880.1">
        <property type="nucleotide sequence ID" value="XM_003710832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRQ3"/>
    <dbReference type="SMR" id="G4MRQ3"/>
    <dbReference type="STRING" id="242507.G4MRQ3"/>
    <dbReference type="GeneID" id="2677939"/>
    <dbReference type="KEGG" id="mgr:MGG_04623"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04623"/>
    <dbReference type="eggNOG" id="KOG1485">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013430_10_1_1"/>
    <dbReference type="InParanoid" id="G4MRQ3"/>
    <dbReference type="OMA" id="KKPIREY"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="Cation diffusion facilitator 10"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Putative Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
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    </dbReference>
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        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF4">
        <property type="entry name" value="CDF DIVALENT METAL CATION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="455"/>
        </location>
    </feature>
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        <location>
            <begin position="276"/>
            <end position="466"/>
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    </feature>
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        <location>
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    </feature>
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        <location>
            <begin position="176"/>
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    </feature>
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        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA58268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="561" mass="62248" checksum="90697C83D1C50E85" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRT4</accession>
    <name>G4MRT4_PYRO7</name>
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        <recommendedName>
            <fullName evidence="5">PUM-HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_13803</name>
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    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
    </comment>
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    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_13803"/>
    <dbReference type="eggNOG" id="KOG2050">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013994_1_0_1"/>
    <dbReference type="InParanoid" id="G4MRT4"/>
    <dbReference type="OMA" id="YGPEFSI"/>
    <dbReference type="OrthoDB" id="497380at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012959">
        <property type="entry name" value="CPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040059">
        <property type="entry name" value="PUM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389:SF0">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08144">
        <property type="entry name" value="CPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="5"/>
    </dbReference>
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        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0677">Repeat</keyword>
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        <location>
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            <end position="510"/>
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    </feature>
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        <location>
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        <location>
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        <location>
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    </feature>
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        <location>
            <begin position="7"/>
            <end position="36"/>
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    </feature>
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        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
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        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="695"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA58299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="724" mass="80483" checksum="52BBC31885D8B2F8" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRU7</accession>
    <name>G4MRU7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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            <end position="101"/>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="90" mass="10257" checksum="B90758E5347AA53F" modified="2011-12-14" version="1">MSGQIKTPESKNGCPTYAARSNHSKRPQKEIAWVGLTVGRCLCAGRLQILMHPKWLRRLCRRSVDSPQQPTVHYMYLCSLAKPTERFQGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS06</accession>
    <name>G4MS06_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
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        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="177" mass="19591" checksum="6F786F578F214029" modified="2011-12-14" version="1">MYQRHYSYECKAAPQERPYVPRPSRTQQLLNPKLRPDLSNDTPELIQKKAGVADAELAKRAAQRESESRGRGLRDDDNEVLSGTSGARSTQNRRRSRSYDSNPSGGSMSPASPRPGRESMSPQRTEVASLQRRSDSPRKGGVAANTVILPNADIHHQKDCCGNHSDTNRMAMESTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">MGG_15848</name>
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            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715258.1">
        <property type="nucleotide sequence ID" value="XM_003715210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSN0"/>
    <dbReference type="GeneID" id="12985603"/>
    <dbReference type="KEGG" id="mgr:MGG_15848"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15848"/>
    <dbReference type="HOGENOM" id="CLU_1875834_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSN0"/>
    <dbReference type="OrthoDB" id="10537881at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="136" mass="15237" checksum="26B76692A5EDBB32" modified="2011-12-14" version="1">MYLRQQGGPTPQVADWVRGMYGCRKALVNFMVTYPCVPQVDNDSSFQPIRHVSCWFREVGGRCHEIIPLLCFFFFAWMGCAMVAHTTVPGNFLTSRHHPLPRLLSLSDICECCMGVTKLTDLTPASAPDLPTCIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT47</accession>
    <name>G4MT47_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SYO1-like TPR repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_07126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclear import and ribosome assembly adapter family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715319.1">
        <property type="nucleotide sequence ID" value="XM_003715271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT47"/>
    <dbReference type="SMR" id="G4MT47"/>
    <dbReference type="FunCoup" id="G4MT47">
        <property type="interactions" value="227"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MT47"/>
    <dbReference type="GeneID" id="2683248"/>
    <dbReference type="KEGG" id="mgr:MGG_07126"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07126"/>
    <dbReference type="eggNOG" id="ENOG502RYAI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028608_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT47"/>
    <dbReference type="OMA" id="ADMDMVT"/>
    <dbReference type="OrthoDB" id="288703at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13394">
        <property type="entry name" value="Syo1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052616">
        <property type="entry name" value="SYO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057990">
        <property type="entry name" value="TPR_SYO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13347">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13347:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25567">
        <property type="entry name" value="TPR_SYO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SYO1-like TPR repeats" evidence="3">
        <location>
            <begin position="411"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA55512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="666" mass="72852" checksum="575090EF87900D4C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW04</accession>
    <name>G4MW04_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_11310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713964.1">
        <property type="nucleotide sequence ID" value="XM_003713916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW04"/>
    <dbReference type="SMR" id="G4MW04"/>
    <dbReference type="STRING" id="242507.G4MW04"/>
    <dbReference type="GeneID" id="2679920"/>
    <dbReference type="KEGG" id="mgr:MGG_11310"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11310"/>
    <dbReference type="eggNOG" id="ENOG502S00D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_758807_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW04"/>
    <dbReference type="OMA" id="PNINQAG"/>
    <dbReference type="OrthoDB" id="5233393at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052998">
        <property type="entry name" value="Hetero-Diels-Alderase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060:SF1">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42060">
        <property type="entry name" value="NHL REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="38485" checksum="2A20F48E44F8594E" modified="2011-12-14" version="1">MGNPVVDAAVYICEKTAPFYRLFSSHPSAHHTASNLLQLPTPPQPHNNETLISSRLYSSSPHFNIKMRFSNFLVGLAPLAAASPLVARQNNQAAAQVALIGGTVESIGVRSNGNLLVSRLDNGQIFSVDMSNRRPSLLVPSLGPNINQAGSMVEIGNDVWYVVGGRANVPGSYGIYKIDLGNTTAGQSVPASTVATIQGSRMLNGLTRGWNDDTLLVGDTLAGMVYRVTISSGEVSAVISNDQALAPGQTVGFGIDGMKYVNNTLFFTNIGKQTFNKISIDDQGKPGSVVQIFSGTPGDDFTFNEAGDAFMATNFQNSVIKVSPEGNITKLATVQGSTCTAFGKTDSTKNMLFVGSGAQVVSLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX63</accession>
    <name>G4MX63_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Retinal pigment epithelial membrane family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_08016</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714968.1">
        <property type="nucleotide sequence ID" value="XM_003714920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX63"/>
    <dbReference type="SMR" id="G4MX63"/>
    <dbReference type="GeneID" id="2678282"/>
    <dbReference type="KEGG" id="mgr:MGG_08016"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08016"/>
    <dbReference type="eggNOG" id="KOG1285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016472_5_0_1"/>
    <dbReference type="InParanoid" id="G4MX63"/>
    <dbReference type="OMA" id="WHIGDYN"/>
    <dbReference type="OrthoDB" id="407010at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF24">
        <property type="entry name" value="CAROTENOID ISOMEROOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="550"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="558" mass="61246" checksum="E1A295A39A533B2D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY46</accession>
    <name>G4MY46_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutaredoxin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714184.1">
        <property type="nucleotide sequence ID" value="XM_003714136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY46"/>
    <dbReference type="SMR" id="G4MY46"/>
    <dbReference type="GeneID" id="2679437"/>
    <dbReference type="KEGG" id="mgr:MGG_01271"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01271"/>
    <dbReference type="eggNOG" id="ENOG502SC8X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125054_0_2_1"/>
    <dbReference type="InParanoid" id="G4MY46"/>
    <dbReference type="OMA" id="SDVWDKR"/>
    <dbReference type="OrthoDB" id="429967at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052565">
        <property type="entry name" value="Glutaredoxin-like_YDR286C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33558">
        <property type="entry name" value="GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33558:SF1">
        <property type="entry name" value="GLUTAREDOXIN-LIKE PROTEIN C5ORF63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="106" mass="12113" checksum="1BF2B5BE939F36DA" modified="2011-12-14" version="1">MRATTRLLQSCRITLFTRENCGLCTSAKTTLSTVWDDRPFIYREIDIIKPEAKAWRDLYDFDVPVIHVSKADAPEENPQLSSRALKLMHRFTPGEVQGKMDAAEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY79</accession>
    <name>G4MY79_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Piwi domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714217.1">
        <property type="nucleotide sequence ID" value="XM_003714169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY79"/>
    <dbReference type="SMR" id="G4MY79"/>
    <dbReference type="STRING" id="242507.G4MY79"/>
    <dbReference type="GeneID" id="2679575"/>
    <dbReference type="KEGG" id="mgr:MGG_01294"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01294"/>
    <dbReference type="eggNOG" id="KOG1041">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004544_4_1_1"/>
    <dbReference type="InParanoid" id="G4MY79"/>
    <dbReference type="OMA" id="HELCYLF"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
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    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
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        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
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        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
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    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="702"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1069" mass="115978" checksum="46E19F574B5E1DD7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYM4</accession>
    <name>G4MYM4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar protein sorting 53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_01331</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VPS53 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA54449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714256.1">
        <property type="nucleotide sequence ID" value="XM_003714208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYM4"/>
    <dbReference type="SMR" id="G4MYM4"/>
    <dbReference type="FunCoup" id="G4MYM4">
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    </dbReference>
    <dbReference type="STRING" id="242507.G4MYM4"/>
    <dbReference type="GeneID" id="2679371"/>
    <dbReference type="KEGG" id="mgr:MGG_01331"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01331"/>
    <dbReference type="eggNOG" id="KOG2180">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007339_1_0_1"/>
    <dbReference type="InParanoid" id="G4MYM4"/>
    <dbReference type="OMA" id="YKFAEAK"/>
    <dbReference type="OrthoDB" id="10261632at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.110">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 53, C-terminus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039766">
        <property type="entry name" value="Vps53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031745">
        <property type="entry name" value="Vps53_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038260">
        <property type="entry name" value="Vps53_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007234">
        <property type="entry name" value="Vps53_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16854">
        <property type="entry name" value="VPS53_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04100">
        <property type="entry name" value="Vps53_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps53 N-terminal" evidence="8">
        <location>
            <begin position="16"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Vps53 C-terminal" evidence="9">
        <location>
            <begin position="614"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="819"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="829"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="838" mass="92482" checksum="C30266833E6B6329" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYW6</accession>
    <name>G4MYW6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_10830</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713434.1">
        <property type="nucleotide sequence ID" value="XM_003713386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYW6"/>
    <dbReference type="SMR" id="G4MYW6"/>
    <dbReference type="FunCoup" id="G4MYW6">
        <property type="interactions" value="710"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYW6"/>
    <dbReference type="GeneID" id="2676345"/>
    <dbReference type="KEGG" id="mgr:MGG_10830"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10830"/>
    <dbReference type="eggNOG" id="KOG3297">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073901_1_0_1"/>
    <dbReference type="InParanoid" id="G4MYW6"/>
    <dbReference type="OMA" id="LGPTLWW"/>
    <dbReference type="OrthoDB" id="10256606at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04330">
        <property type="entry name" value="RNAP_III_Rpc25_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000221">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013238">
        <property type="entry name" value="RNA_pol_III_Rbc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08292">
        <property type="entry name" value="RNA_pol_Rbc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="8">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase III subunit Rpc25" evidence="9">
        <location>
            <begin position="83"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="213" mass="24465" checksum="333E224B2BE2914A" modified="2011-12-14" version="1">MFILTKIADLVQIKPAQFAKLSIDAIEDNLNEKYCNKVIQKVGLCICMYDLLWASEGLIGHGDGLVNVNVECRLVIFRPFKGEVLFGRISRCVKDGIHLRTDFFDDIFVPFDELPEGATFDHDQSLWVWHVEDQEMYYDIHEMVRFRVSSEEWQDQTPTKPIEGSELPEKKPPYRITGTMKEEGLGVCLWWGDDGGGVVEEEKVENGDMEVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZE2</accession>
    <name>G4MZE2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication factor C subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_04389</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713504.1">
        <property type="nucleotide sequence ID" value="XM_003713456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZE2"/>
    <dbReference type="SMR" id="G4MZE2"/>
    <dbReference type="FunCoup" id="G4MZE2">
        <property type="interactions" value="625"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZE2"/>
    <dbReference type="GeneID" id="2678221"/>
    <dbReference type="KEGG" id="mgr:MGG_04389"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04389"/>
    <dbReference type="eggNOG" id="KOG0989">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042324_1_0_1"/>
    <dbReference type="InParanoid" id="G4MZE2"/>
    <dbReference type="OMA" id="GCQSGSF"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902983">
        <property type="term" value="P:DNA strand elongation involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000011">
        <property type="entry name" value="Replication factor C subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000237">
        <property type="entry name" value="replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF20">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="66"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="384" mass="42297" checksum="6A70F1AF3F4FB254" modified="2011-12-14" version="1">MASFFDLKARKQAAANGATTAKQEKQNPENTRTQPWVEKYRPKTLSDVTAQDHTVTVLQRTLQASNLPHMLFYGPPGTGKTSTVLALAKELFGPELMKSRVLELNASDERGISIVREKVKDFARMQLTNPPPGYKSKYPCPPFKIIILDEADSMTQDAQSALRRTMETYSKITRFCLICNYVTRIIDPLASRCSKFRFKSLDQENARSRLEDIAAKEGVALEDGAVDALIKCSEGDLRKAITFLQSAARLVGAVGAAGAGQEDKMDVDSRPVTVRIIEDIAGVIPGKTIDALVEAIRPRGAALTYQAVSKVVEDMVADGWSATQVVGQLYQAIVYDEGIPNIQKNEIVMVFSEVDKRLVDGSDEHLSILDLCLRISVIMSGRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZH4</accession>
    <name>G4MZH4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_01396</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714340.1">
        <property type="nucleotide sequence ID" value="XM_003714292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZH4"/>
    <dbReference type="SMR" id="G4MZH4"/>
    <dbReference type="STRING" id="242507.G4MZH4"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
    </dbReference>
    <dbReference type="GeneID" id="2679138"/>
    <dbReference type="KEGG" id="mgr:MGG_01396"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01396"/>
    <dbReference type="eggNOG" id="ENOG502QQ55">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_5_1_1"/>
    <dbReference type="InParanoid" id="G4MZH4"/>
    <dbReference type="OMA" id="MSAYHSY"/>
    <dbReference type="OrthoDB" id="2123594at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000495">
        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000009">
        <property type="entry name" value="Periplasmic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051915">
        <property type="entry name" value="Cellulose_Degrad_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620:SF117">
        <property type="entry name" value="BETA-1,4-XYLOSIDASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30620">
        <property type="entry name" value="PERIPLASMIC BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465561" description="beta-glucosidase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="10">
        <location>
            <begin position="700"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA54533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="781" mass="84309" checksum="85B3599010EC1B51" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZM0</accession>
    <name>G4MZM0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714386.1">
        <property type="nucleotide sequence ID" value="XM_003714338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZM0"/>
    <dbReference type="SMR" id="G4MZM0"/>
    <dbReference type="GeneID" id="2679330"/>
    <dbReference type="KEGG" id="mgr:MGG_01436"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01436"/>
    <dbReference type="eggNOG" id="ENOG502S9VZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034666_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZM0"/>
    <dbReference type="OMA" id="FQHENPP"/>
    <dbReference type="OrthoDB" id="3197614at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40130">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40130:SF1">
        <property type="entry name" value="SPINDLE POLE BODY-ASSOCIATED PROTEIN CUT12 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="348"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="441"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
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        </location>
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        </location>
    </feature>
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        </location>
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            <end position="135"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA54579.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZW7</accession>
    <name>G4MZW7_PYRO7</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA51411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_09110"/>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="456" mass="50597" checksum="15B1C6864E9B506C" modified="2011-12-14" version="1">MSSAYHASYPATGQYYEYSQPSYTAYTQPSYTLEAHPYADAYTTTAGRLTPDYREPRTSSSRRTSISPSSSGECSHTSSGASGHHRRRSSQIYLEEPTRIVHSSGSPSRRDRERAERAEREEREAKEERRRRRREDKVSAPSSKAMPIPLPRSSTMPTGLTPSHETRGRRPVIMSEYVDNGETSARMPIGPVDVLEHASSRRNSTTKRYSSTGRYEDHHRRSSSSGHRRHDSNGSSGSSSSHGHRRHDSNGGSPHGYASGEEEANRRRAQRRSNRAEVRQGPGFAASAPDFGVAYGKSPSHYASSYASTAGSAHLSSSPAADEATKTLRWADQERRAQNDRISSRPKLARVDSVKANASAKTQGEVKGILKNSPNNSRPQSSSGPRSRGNSVNVDDLATGVERLSTSERGEDEYRRLKDRFSMPPTRRHSTFGPGAGSRDRTEYWADGGREKRYYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N075</accession>
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            <fullName evidence="2">Phosphatidate phosphatase APP1 catalytic domain-containing protein</fullName>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA53110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003712869.1"/>
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    <dbReference type="STRING" id="242507.G4N075"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_07714"/>
    <dbReference type="eggNOG" id="ENOG502QT5E">
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    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052935">
        <property type="entry name" value="Mg2+_PAP"/>
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    <dbReference type="PANTHER" id="PTHR28208">
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        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR28208:SF3">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037464">
        <property type="entry name" value="UCP037464_APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        </location>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="820" mass="89710" checksum="0A3BA406F8BC31A8" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0H6</accession>
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    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6590 domain-containing protein</fullName>
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            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712117.1">
        <property type="nucleotide sequence ID" value="XM_003712069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0H6"/>
    <dbReference type="STRING" id="242507.G4N0H6"/>
    <dbReference type="GeneID" id="5049164"/>
    <dbReference type="KEGG" id="mgr:MGG_13309"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13309"/>
    <dbReference type="eggNOG" id="ENOG502SV73">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_301290_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0H6"/>
    <dbReference type="OMA" id="WTANMAV"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
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    <dbReference type="InterPro" id="IPR046497">
        <property type="entry name" value="DUF6590"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF7">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
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    <dbReference type="Pfam" id="PF20233">
        <property type="entry name" value="DUF6590"/>
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            <end position="961"/>
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        <location>
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            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="650"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="688"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="733"/>
            <end position="745"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF20233"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA52310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0R3</accession>
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        <submittedName>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51496.1"/>
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    <dbReference type="InParanoid" id="G4N0R3"/>
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        <location>
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            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="55" mass="6189" checksum="EE801D5A31A707EB" modified="2011-12-14" version="1">MTNMTCSMVNCGSSNYEMDEDPKPRQTPCSDKRTRPAKDLGASHAGSKRRDWVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0U4</accession>
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        <recommendedName>
            <fullName evidence="4">aldehyde dehydrogenase (NAD(+))</fullName>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the aldehyde dehydrogenase family.</text>
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    <dbReference type="EMBL" id="CM001233">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003712081.1"/>
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    <dbReference type="SMR" id="G4N0U4"/>
    <dbReference type="STRING" id="242507.G4N0U4"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_05814"/>
    <dbReference type="eggNOG" id="KOG2450">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_005391_1_0_1"/>
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    <dbReference type="OMA" id="FPEGCFQ"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
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    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="CDD" id="cd07102">
        <property type="entry name" value="ALDH_EDX86601"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldehyde dehydrogenase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000012">
        <property type="entry name" value="NAD-dependent succinate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="5"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA52322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="470" mass="51055" checksum="FC09A9DD23424D30" modified="2011-12-14" version="1">MGSVETLTTISPTTNEGILQRTGVSLSELEQLPKTATEAFKSWSKTTLADRQIIIRKALEGLSAKKDELANELTVQMGRPIAYTGGEVATAIKRAEYLLKISDEVLKDTDGEAEKGFKRLIRKVPVGPVLVIFAWNYPYLILVNSLIPALLAGNTVILKPSPQTPTIVEQVAGVFADAGLPQGVIQYFHCGSPTLMETIVRDPLVKHVCFTGSVAGGLAVQKAASDRIVNVGLELGGKDPAYVRSDVDVDWVAGEIVDGAVFNSGQSCCSIERVYVHDDIHDKFVAAVQKVLEGYVLGDPLDKGTHVGPVVSKRSKEAIEAHVKEAIEKGAKDATPKNESFDTVPSSSKGNFVKPTLLVNVNHSMQVMKDETFGPVIPVMRVKSDEEAVQLMNDSEFGLTASIWTKDTDTAAKLIDDVEAGTVFVNRCDYPSPDLAWTGWKNSGKGQTLSRFGFDQFVKLKSYHMKDYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0X6</accession>
    <name>G4N0X6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09576</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712161.1">
        <property type="nucleotide sequence ID" value="XM_003712113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0X6"/>
    <dbReference type="GeneID" id="2680551"/>
    <dbReference type="KEGG" id="mgr:MGG_09576"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09576"/>
    <dbReference type="eggNOG" id="ENOG502QVDR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038276_0_1_1"/>
    <dbReference type="InParanoid" id="G4N0X6"/>
    <dbReference type="OMA" id="DEPFCAP"/>
    <dbReference type="OrthoDB" id="4084551at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028000">
        <property type="entry name" value="Pma1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14610">
        <property type="entry name" value="Psg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465811" evidence="3">
        <location>
            <begin position="25"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="372" mass="41171" checksum="F2729593FD194527" modified="2011-12-14" version="1">MASRRLLALGATILWFMTMPLVSASIPHSRRQAATAAAPLKPWITIDKDGAARTITPTVTTTNQAVQTLSGAPSSLTAESTWFLSNNGMTTTTVFAPHPAPTSDYGMQRGAFLVCESYYGQDMPFCTPKRGSMLNPKWAYYITWNPQHFAHQDDKLKIEVVYDDSRADVIAQSVRASVGYYAWIIPEDMLTKFNTTAMNASIKYNYQSHDSSEFNEIRGNGPRVVITEDVMWSMYNTGGNGSPGPISTVVVVPIVVVLFIALGIYCFWSYRKKALVPFVASFANLKRNLGRVRGSHGYGVRKSRSERTGTANPTQDAEIARVAARGDSFRANYQPEDKTPGIQLTSSESWSPTSTFGTNVFREEIQRQDGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4N133</accession>
    <name>G4N133_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713016.1">
        <property type="nucleotide sequence ID" value="XM_003712968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N133"/>
    <dbReference type="GeneID" id="12985893"/>
    <dbReference type="KEGG" id="mgr:MGG_16931"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16931"/>
    <dbReference type="HOGENOM" id="CLU_2590208_0_0_1"/>
    <dbReference type="InParanoid" id="G4N133"/>
    <dbReference type="OMA" id="LYAQCAD"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="80" mass="9185" checksum="A2C2894EADECE804" modified="2011-12-14" version="1">MFNWQIEKRDHAVLADEHNIKNMLFLLPCYQALEPFDSDLYAQCADTGTNLGAGCVRLRPDNVWLGISCLEVDFFDPCYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1U2</accession>
    <name>G4N1U2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712264.1">
        <property type="nucleotide sequence ID" value="XM_003712216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1U2"/>
    <dbReference type="GeneID" id="12984954"/>
    <dbReference type="KEGG" id="mgr:MGG_16800"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16800"/>
    <dbReference type="HOGENOM" id="CLU_2979576_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1U2"/>
    <dbReference type="OMA" id="DVNMYKV"/>
    <dbReference type="OrthoDB" id="10434515at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="58" mass="6368" checksum="B204565B0FE0AAEF" modified="2011-12-14" version="1">MSVPEQLSDVNMYKVKANYKLFLKPARPDKSVISPLRPLNPPVTAAPQTQVSSSQEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2K5</accession>
    <name>G4N2K5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711521.1">
        <property type="nucleotide sequence ID" value="XM_003711473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2K5"/>
    <dbReference type="GeneID" id="12984132"/>
    <dbReference type="KEGG" id="mgr:MGG_16665"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16665"/>
    <dbReference type="HOGENOM" id="CLU_2776421_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2K5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="69" mass="7408" checksum="44C5496FDF1AB712" modified="2011-12-14" version="1">MEQLEEVGAAARLQFPSSTPTNIHLLNTIARAMFPKVGSRVGVKTSASRNLKEDTIGVSRDMSHTSPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3B0</accession>
    <name>G4N3B0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="5">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_16993</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="5"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713262.1">
        <property type="nucleotide sequence ID" value="XM_003713214.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N3B0"/>
    <dbReference type="GeneID" id="12986160"/>
    <dbReference type="KEGG" id="mgr:MGG_16993"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16993"/>
    <dbReference type="eggNOG" id="KOG0351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001104_6_0_1"/>
    <dbReference type="InParanoid" id="G4N3B0"/>
    <dbReference type="OMA" id="INECHIV"/>
    <dbReference type="OrthoDB" id="5244177at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF154">
        <property type="entry name" value="RECQ HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="872"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="1047"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="628"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="630"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="654"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="728"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA53455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1283" mass="145320" checksum="DA1469A9E3DF1186" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3I8</accession>
    <name>G4N3I8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712470.1">
        <property type="nucleotide sequence ID" value="XM_003712422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3I8"/>
    <dbReference type="STRING" id="242507.G4N3I8"/>
    <dbReference type="GeneID" id="5048896"/>
    <dbReference type="KEGG" id="mgr:MGG_12961"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12961"/>
    <dbReference type="eggNOG" id="ENOG502QQEZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020826_1_2_1"/>
    <dbReference type="InParanoid" id="G4N3I8"/>
    <dbReference type="OMA" id="TAETWAH"/>
    <dbReference type="OrthoDB" id="442243at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842:SF1">
        <property type="entry name" value="DUF676 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47842">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="44235" checksum="5B7CA4BD77F3E2AF" modified="2011-12-14" version="1">MKKTLLLCFIHGFKGGDDTFGRPSDGFTEQLRQLVAAQLPKIDVRVVIYPKYDTRGDLAECVARFRDWLLEKVIDIEVDAGTPSPTVDPSVRTVLIGHSMGGIVAAETIMALTSEKPIPAPGSADDQAFDAEAAAAAAAKRPTSPSLTSLMFPYIQGLLAFDTPFLGISPGVVAHGAEGHYNQASAVLGQISGLSGALWGGGAAAAAGDKARSADGKRQAEALPMAAPPATASQDKNQKGNDGGAWGQWGKMAMIAGAGAAIAAGGAAAYMKREQISEGWSWASSHLAFVGCLARGEELRRRVAYMSRTKSDLGIGFANLYTRLGKAAAPKQVSMVGTVLGNQRTFCNLPTKSSANAGEWREAINDMATDETLAHTSMFEKPQNPGFEKLKTDAAELITSWAKNDWYESSAEEPAKIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3X6</accession>
    <name>G4N3X6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_15241</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711705.1">
        <property type="nucleotide sequence ID" value="XM_003711657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3X6"/>
    <dbReference type="SMR" id="G4N3X6"/>
    <dbReference type="STRING" id="242507.G4N3X6"/>
    <dbReference type="GeneID" id="12984191"/>
    <dbReference type="KEGG" id="mgr:MGG_15241"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15241"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_3_1_1"/>
    <dbReference type="InParanoid" id="G4N3X6"/>
    <dbReference type="OMA" id="CTHGFTH"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="102"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="387" mass="43197" checksum="9DB0FF8833C361A3" modified="2011-12-14" version="1">MLATTRTKAAGGPTSASATPGHFQPRLPLVKRMLCWLQAAIFTGLMGALKTLKPVVDKIFPQSFHPTLIKNYKSRPGLPIRVFFPKGYDHKNPQGNPLPCLFSIHGGGFVVGIPDLNDDWNHHFCNTHSAIVIALNYRKAPRHPFPTPIHDVTALITTVLDDHKDLARHIDPNRVAVAGFSAGGSLTLAVAQQPQIRSRIQAIVPVYPACDFATPTDVKVRLRRYKEGLKGFRARKSDFLVYMMACFNWSYIPVGHDLTDPLLSGEVLPASALPKRVFIIAAEMDLLAHGAWRLACRLAGKPVPGYDQEVGRPELQPPHRLNLDDEAYHWLQKTKDGREVRWLLAPDAVHAFDMEAKLLAPFDKVMKADCRAKRDEEIEIIGKWLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4H7</accession>
    <name>G4N4H7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05124</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712652.1">
        <property type="nucleotide sequence ID" value="XM_003712604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4H7"/>
    <dbReference type="GeneID" id="2675679"/>
    <dbReference type="KEGG" id="mgr:MGG_05124"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05124"/>
    <dbReference type="eggNOG" id="ENOG502SPX8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022883_4_1_1"/>
    <dbReference type="InParanoid" id="G4N4H7"/>
    <dbReference type="OMA" id="WRASSIT"/>
    <dbReference type="OrthoDB" id="3061561at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35043:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466110" evidence="3">
        <location>
            <begin position="19"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="395" mass="43787" checksum="16F12594B6448EA9" modified="2011-12-14" version="1">MKWMVCLLVLPEIPLLLAVMDFANARAEMNKFKYCEAEFDSWFRSSGRGGVDGARITMSHAYYASMGGIELVLSSESQAAAEIERRAADVESGSRVQPATTPRMRVLDSKRRLDLGEYIDFLRNLESDSHRASFLLSEADIQGFSKSDSMTKLLAITQIFYLVATCIARNRSGLPISLLELVTMGYIAHSAMMYCLWWHKPYDAEHVTRVYATVPATPGSGGARNRFPEPDPLDSGGGEQQHALANETSRSKGMLATGGIRHLYRELSTRSNDDHVTNTATAISSIIMGLANYIALVAWSWVFASPVEQWIWRASSITANLALFLSLSSWMLKDASLGNSSRIAAPIFSVLLWVLPLVYISARLALIGVSIRSLFWMPANMYDVVPWTAYLPSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4V4</accession>
    <name>G4N4V4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_06024</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711873.1">
        <property type="nucleotide sequence ID" value="XM_003711825.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N4V4"/>
    <dbReference type="GeneID" id="2683951"/>
    <dbReference type="KEGG" id="mgr:MGG_06024"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06024"/>
    <dbReference type="eggNOG" id="KOG0054">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_27_1_1"/>
    <dbReference type="InParanoid" id="G4N4V4"/>
    <dbReference type="OMA" id="AITYWLS"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="579"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="621"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="812"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="68"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="282"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="581"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="914"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1229"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1252"/>
            <end position="1271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA52066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1354" mass="147108" checksum="A27DE8F36676D080" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8V4</accession>
    <name>G4N8V4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_03378</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC4 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716567.1">
        <property type="nucleotide sequence ID" value="XM_003716519.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N8V4"/>
    <dbReference type="FunCoup" id="G4N8V4">
        <property type="interactions" value="829"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N8V4"/>
    <dbReference type="GeneID" id="2676897"/>
    <dbReference type="KEGG" id="mgr:MGG_03378"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03378"/>
    <dbReference type="eggNOG" id="KOG0996">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001042_4_1_1"/>
    <dbReference type="InParanoid" id="G4N8V4"/>
    <dbReference type="OMA" id="CPALDNM"/>
    <dbReference type="OrthoDB" id="5575062at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1620:FF:000003">
        <property type="entry name" value="Structural maintenance of chromosomes 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000481">
        <property type="entry name" value="Structural maintenance of chromosomes 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000585">
        <property type="entry name" value="Structural maintenance of chromosomes 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF172">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="14">
        <location>
            <begin position="758"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1215"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="528"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="911"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1266"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1215"/>
            <end position="1227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA50248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1496" mass="167294" checksum="880E1A22A1603290" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9Q3</accession>
    <name>G4N9Q3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peroxin 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_13641</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717560.1">
        <property type="nucleotide sequence ID" value="XM_003717512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9Q3"/>
    <dbReference type="FunCoup" id="G4N9Q3">
        <property type="interactions" value="57"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9Q3"/>
    <dbReference type="GeneID" id="5050060"/>
    <dbReference type="KEGG" id="mgr:MGG_13641"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13641"/>
    <dbReference type="eggNOG" id="ENOG502QT80">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016397_1_0_1"/>
    <dbReference type="InParanoid" id="G4N9Q3"/>
    <dbReference type="OMA" id="AWTDERN"/>
    <dbReference type="OrthoDB" id="5586090at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006614">
        <property type="entry name" value="Peroxin/Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052646">
        <property type="entry name" value="Peroxisomal_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00693">
        <property type="entry name" value="DysFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Peroxin/Ferlin" evidence="6">
        <location>
            <begin position="413"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="168"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="545"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="608"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="612"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="663"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA51241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="679" mass="73696" checksum="A97C486912764141" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9W0</accession>
    <name>G4N9W0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_03243</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716731.1">
        <property type="nucleotide sequence ID" value="XM_003716683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9W0"/>
    <dbReference type="SMR" id="G4N9W0"/>
    <dbReference type="STRING" id="242507.G4N9W0"/>
    <dbReference type="GeneID" id="2676749"/>
    <dbReference type="KEGG" id="mgr:MGG_03243"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03243"/>
    <dbReference type="eggNOG" id="KOG0885">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_14_5_1"/>
    <dbReference type="InParanoid" id="G4N9W0"/>
    <dbReference type="OMA" id="CKNFLQH"/>
    <dbReference type="OrthoDB" id="442970at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01925">
        <property type="entry name" value="cyclophilin_CeCYP16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000034">
        <property type="entry name" value="Peptidyl-prolyl isomerase CWC27 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF6">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 17" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0697">Rotamase</keyword>
    <keyword evidence="8" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="16">
        <location>
            <begin position="18"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="216"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="525"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="265"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="349"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="432"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="557"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA50412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="573" mass="62753" checksum="4DB53AAE40040ED2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9Y9</accession>
    <name>G4N9Y9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conidiophore development protein hymA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716760.1">
        <property type="nucleotide sequence ID" value="XM_003716712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9Y9"/>
    <dbReference type="SMR" id="G4N9Y9"/>
    <dbReference type="FunCoup" id="G4N9Y9">
        <property type="interactions" value="384"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9Y9"/>
    <dbReference type="GeneID" id="2676418"/>
    <dbReference type="KEGG" id="mgr:MGG_03219"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03219"/>
    <dbReference type="eggNOG" id="KOG1566">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035755_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9Y9"/>
    <dbReference type="OMA" id="AYDHKES"/>
    <dbReference type="OrthoDB" id="609103at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000257">
        <property type="entry name" value="Conidiophore development protein hymA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="371" mass="42450" checksum="FAF252CA49EC702C" modified="2011-12-14" version="1">MYSLNLFNRGRTRTNTIDLPKQARENVLKLDNPAAKAEELSKVLNQMKLILQGTHDSESNPDQVFHLIEGIINEDLLHPLAANLHKLPFESRKDAQFIFSSVFRFRPASASTKSDPVALGWVVNQRPQVLLELCRGYDHKESATAAGSVLREVLKHEGACKVILYDDGDQPGSSVNGVQAIDRDRPQSGTGVFWKFFDWIDRGSFEVSADAFTTFREILTKQKEVVPHYLRVNFDLFCSKYNTVLVQSSSYVTKRQSIKLLGEILLDRSNYSVMTEYVASGEHLKICMNLLRDDRKMVQYEGFHVFKVFVANPNKSIPVQRILIMNKDKLLNFLSHFLEDRTDDEQFIDEREFLIKQIRNMPASPVPPQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA87</accession>
    <name>G4NA87_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_13946</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715956.1">
        <property type="nucleotide sequence ID" value="XM_003715908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA87"/>
    <dbReference type="GeneID" id="5049267"/>
    <dbReference type="KEGG" id="mgr:MGG_13946"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13946"/>
    <dbReference type="eggNOG" id="ENOG502SNI4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_5_1"/>
    <dbReference type="InParanoid" id="G4NA87"/>
    <dbReference type="OMA" id="LYTIMAW"/>
    <dbReference type="OrthoDB" id="5022096at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF167">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="30"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="346"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="391" mass="42646" checksum="540E895D3A757526" modified="2011-12-14" version="1">MSSRAEESNTEWLMGVMCTFYALAIFSVCLRMYTRLVVVKSPGLDDYFMVAAAACATVGMATHGVQSQNGMGKHYEFITPPMRVEYSKFGFFQSIINNTGGISILKVSIALSLLKLGGGNRAYTNTLYAFLALTAAVTIYAWCTLIFFCDPVHGYWDKTINPKCYDIKLFVVFGLVHTAVNMFTDVAFALLPIPIIWMLQMKKRTKIYLCIVLSLGLIAVVMGVLKATYQIKHGGDRDVAFMHGVQFWAFLQLNTGIIAACAPTLKPLLGRTLHLGSTAKPRSYGNSSSAMYFDSKGNNRSRSNRGYINHTDNDEVDIELSRTSRQILGGGVGSFHAGAVGGAEALRQQQQQHGGGSSSASKGADSQSEEFILQGTAEGGILRTTEISIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAD6</accession>
    <name>G4NAD6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716800.1">
        <property type="nucleotide sequence ID" value="XM_003716752.1"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAD6"/>
    <dbReference type="GeneID" id="2676997"/>
    <dbReference type="KEGG" id="mgr:MGG_12761"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12761"/>
    <dbReference type="eggNOG" id="ENOG502QSDS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000374_1_0_1"/>
    <dbReference type="InParanoid" id="G4NAD6"/>
    <dbReference type="OMA" id="DNRIDYM"/>
    <dbReference type="OrthoDB" id="2386201at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035361">
        <property type="term" value="C:Cul8-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019021">
        <property type="entry name" value="Mms22"/>
    </dbReference>
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        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SUBSTRATE RECEPTOR MMS22"/>
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        <property type="entry name" value="Mus7"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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    </feature>
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            <end position="507"/>
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    </feature>
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            <end position="630"/>
        </location>
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            <begin position="9"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA50481.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
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    <sequence length="2162" mass="240432" checksum="7CCCC6C47705B950" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49694.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB63</accession>
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            <fullName evidence="4 11">Pectinesterase</fullName>
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    </protein>
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        <name evidence="13" type="ORF">MGG_00618</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in maceration and soft-rotting of plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1-&gt;4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)</text>
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            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14573"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:140522"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pectinesterase family.</text>
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        <property type="nucleotide sequence ID" value="XM_003718361.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_00618"/>
    <dbReference type="eggNOG" id="ENOG502QSQ4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012243_1_0_1"/>
    <dbReference type="InParanoid" id="G4NB63"/>
    <dbReference type="OMA" id="WDRSENE"/>
    <dbReference type="OrthoDB" id="2019149at2759"/>
    <dbReference type="UniPathway" id="UPA00545">
        <property type="reaction ID" value="UER00823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000014">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033131">
        <property type="entry name" value="Pectinesterase_Asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF127">
        <property type="entry name" value="PECTINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00503">
        <property type="entry name" value="PECTINESTERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005132187" description="Pectinesterase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="12">
        <location>
            <begin position="35"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA48825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="325" mass="34727" checksum="19D37316E9E214E1" modified="2011-12-14" version="1">MVSLTLAILSLAAGALGASRTSAPSGCITVKSGASIQQAVNSLSTTASGTQCIFLERGTYREQVLVPARKAQLTIYGYSTDTLSHNANGALITQRKSQKDGLSNDETATLRVKAANFRLYNVNVDNAYGEGSQAVALSAYADSGYYGCRFTGFQDTVLANQGKQLYARCLVQGATDFVFGQYAAAWFEKNDVRVLGKSLGYITANGRLDNSNPSYYVFNNCNVAAASGQSVPRGAYYLGRPWREFARVVFQNTAMTEVINSAGWKTWNTGDERISNVLFGEYANSGAGSQGQRASFSKKLGSAVGIDSILGSGHRSAAFYDGSYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBD4</accession>
    <name>G4NBD4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ent-kaurene oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_11075</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717677.1">
        <property type="nucleotide sequence ID" value="XM_003717629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBD4"/>
    <dbReference type="SMR" id="G4NBD4"/>
    <dbReference type="GeneID" id="2684807"/>
    <dbReference type="KEGG" id="mgr:MGG_11075"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11075"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_3_1"/>
    <dbReference type="InParanoid" id="G4NBD4"/>
    <dbReference type="OMA" id="IEWFERT"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF2">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE AUSG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA48093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="60098" checksum="26CF421C4241EA03" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBX9</accession>
    <name>G4NBX9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phospholipid metabolism enzyme regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717766.1">
        <property type="nucleotide sequence ID" value="XM_003717718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBX9"/>
    <dbReference type="STRING" id="242507.G4NBX9"/>
    <dbReference type="GeneID" id="2674972"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01156"/>
    <dbReference type="eggNOG" id="ENOG502QU5B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4NBX9"/>
    <dbReference type="OMA" id="QHRYHSR"/>
    <dbReference type="OrthoDB" id="1204at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010513">
        <property type="term" value="P:positive regulation of phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903778">
        <property type="term" value="P:protein localization to vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000011">
        <property type="term" value="P:vacuole inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024260">
        <property type="entry name" value="Vac7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28258">
        <property type="entry name" value="VACUOLAR SEGREGATION PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28258:SF1">
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
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                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
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                <person name="Bohnert H."/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
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                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
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                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
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                <person name="Gujja S."/>
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                <person name="MacDonald P.J.P."/>
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                <person name="Yandava C."/>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF00487"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA49100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="371" mass="44380" checksum="43F9B8CE32609844" modified="2011-12-14" version="1">MSDPKHADFEPTVFVSTDLRDLQLPKAVNHWLLQPYIRWAQGIVRTKTDVVMWTHLLIYFTTTIPSAAYLLLVHFSWTHGVLHFLMQLFYMPTYTLMMHQHIHQRGVLAKSWAWLDRSFPFVLDPLMGHTWNSYYYHHVKHHHVEGNGPGDLSSTIYFQRDNAWHFAQYVGRFYFLVWLDLPLYFMRKKKYELAARAAWSECFSYFAMYCLWRFLDSRAAFMVVILPFLLLRLAFMAGNWGQHAFVDWEDADSDYRSSITLIDVPSNRYCFNDGYHTSHHLNPLRHWRQHPVSFIKEKETYAREKALVFHGLDFNMITIKCLQKDYMYLAQRLVPLGDQVHMTMEERADMLRQHTRQFTKEDIARKFRTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCQ0</accession>
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        <recommendedName>
            <fullName evidence="6">Transcriptional activator HAP2</fullName>
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    </gene>
    <organism evidence="8 9">
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NFYA/HAP2 subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718728.1">
        <property type="nucleotide sequence ID" value="XM_003718680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCQ0"/>
    <dbReference type="SMR" id="G4NCQ0"/>
    <dbReference type="STRING" id="242507.G4NCQ0"/>
    <dbReference type="GeneID" id="2674960"/>
    <dbReference type="KEGG" id="mgr:MGG_00354"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00354"/>
    <dbReference type="eggNOG" id="KOG1561">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045001_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCQ0"/>
    <dbReference type="OMA" id="MGSQVQM"/>
    <dbReference type="OrthoDB" id="1097733at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12632">
        <property type="entry name" value="TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00616">
        <property type="entry name" value="CCAATSUBUNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="93"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="206"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA49144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="306" mass="33385" checksum="0AB808029DA96C12" modified="2011-12-14" version="1">MMEYAQYQQPPQNAHSNFQSSTASNNITSPTSQHVQTSPIIPQQNQQAANANQTHMYQPPYGVPQQSLHYGMPGIQAAALAATAAASGSNYPYSLPSDPSLQQTSPRMGSKKEARGNPRSPQQMDAQRRMSQVTSPGLPNAQAMMNHTGARPGVAAPTMPAQQMGPPQSPEIAAGAVEESPLYVNAKQFHRILKRRVARQKLEEQLRLTSKGRKPYLHESRHNHAMRRPRGPGGRFLTADEVLEIEKQKGLGGAESEIKHDVESSPPAKANNKRKSMSVPDTANKKAKVDTESPDVEEEEDAEDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCZ8</accession>
    <name>G4NCZ8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-L-fucosidase</fullName>
            <ecNumber evidence="2">3.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00316</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 29 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.51" evidence="2"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718772.1">
        <property type="nucleotide sequence ID" value="XM_003718724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCZ8"/>
    <dbReference type="SMR" id="G4NCZ8"/>
    <dbReference type="STRING" id="242507.G4NCZ8"/>
    <dbReference type="CAZy" id="GH29">
        <property type="family name" value="Glycoside Hydrolase Family 29"/>
    </dbReference>
    <dbReference type="GeneID" id="2674808"/>
    <dbReference type="KEGG" id="mgr:MGG_00316"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00316"/>
    <dbReference type="eggNOG" id="KOG3340">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002934_4_1_1"/>
    <dbReference type="InParanoid" id="G4NCZ8"/>
    <dbReference type="OMA" id="WWYSTHH"/>
    <dbReference type="OrthoDB" id="6039950at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016139">
        <property type="term" value="P:glycoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000933">
        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057739">
        <property type="entry name" value="Glyco_hydro_29_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030:SF37">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01120">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00812">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466117" description="alpha-L-fucosidase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 29 N-terminal" evidence="7">
        <location>
            <begin position="320"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA49188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="803" mass="88564" checksum="869F5C2B30A3A7FD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND04</accession>
    <name>G4ND04_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718778.1">
        <property type="nucleotide sequence ID" value="XM_003718730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND04"/>
    <dbReference type="GeneID" id="5049780"/>
    <dbReference type="KEGG" id="mgr:MGG_14702"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14702"/>
    <dbReference type="eggNOG" id="ENOG502RVMB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078024_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND04"/>
    <dbReference type="OMA" id="MFFWNAN"/>
    <dbReference type="OrthoDB" id="2332199at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="260" mass="28637" checksum="DC3191EF6D8C3558" modified="2011-12-14" version="1">MGISHSTARWLAPLSFVVDFAAQQYGIYGSTPTMKDVHDANMSFFSPQAYFIGAFFFPQQLFQLAWLWKLHNSDPEEEDTKEMVDFAPFYAAGNFAIAAWMIFWCNNDLRTSNYFVIANSLMQLFYVFGRLRPMRLDSTRSVLTHVNAKTFAGIGVLDLLHNTAAGYFVHGRPSGVVKALTAVGFGALGASSDWIFGGCLVYDLVALAVGQSQYGDAGWSKMLGAYAVGTAGIVAARNYFRPPYIKSSGYEPVRGTSRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND45</accession>
    <name>G4ND45_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00978</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717971.1">
        <property type="nucleotide sequence ID" value="XM_003717923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND45"/>
    <dbReference type="SMR" id="G4ND45"/>
    <dbReference type="STRING" id="242507.G4ND45"/>
    <dbReference type="GeneID" id="2675199"/>
    <dbReference type="KEGG" id="mgr:MGG_00978"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00978"/>
    <dbReference type="eggNOG" id="KOG0810">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042423_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND45"/>
    <dbReference type="OMA" id="RWICFIL"/>
    <dbReference type="OrthoDB" id="10255013at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF307">
        <property type="entry name" value="PROTEIN SSO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="231"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA48387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="345" mass="39268" checksum="DDB4EEEE61C0BEEF" modified="2011-12-14" version="1">MSYNNQQQYGGNPYGQAPATEAGYGYGNGGNEHEMQQYGQPQQQQQYGQGQNGYGYGHGQQQQEPAGPPVMSQQDFLGQVTFTRGEINRLTSDVQTIATLHSRSLQGGDAGAQQQLEQQIAETSRRTTSIRTTIKQLKKDVEHTQDGSRSIKERQWNTLNDTFKQELRNYIQEEQRYKEGYREQIARQYRIVNPDASEDEVRRAADQNWGDEGVFQQALRQNRVAQGQAVLGAVRARHNEMRQIEDSIVELAKMFEDLDTLVIQQEPIVQRVEQQAEDTTQNLNHANTEVKKAADHAKNRRKLKWWCLGITTVIIIAIIVAIVAAGFTQCWWPSEQCKKRNGNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND61</accession>
    <name>G4ND61_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA48403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
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        <name evidence="15" type="ORF">MGG_00222</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <text evidence="13">Subunit of dynactin, a multiprotein complex part of a tripartite complex with dynein and a adapter, such as BICDL1, BICD2 or HOOK3. The dynactin complex is built around ACTR1A/ACTB filament and consists of an actin-related filament composed of a shoulder domain, a pointed end and a barbed end. Its length is defined by its flexible shoulder domain. The soulder is composed of 2 DCTN1 subunits, 4 DCTN2 and 2 DCTN3. The 4 DCNT2 (via N-terminus) bind the ACTR1A filament and act as molecular rulers to determine the length. The pointed end is important for binding dynein-dynactin cargo adapters. Consists of 4 subunits: ACTR10, DCNT4, DCTN5 and DCTN6. The barbed end is composed of a CAPZA1:CAPZB heterodimers, which binds ACTR1A/ACTB filament and dynactin and stabilizes dynactin. Interacts with ATP7B, but not ATP7A, in a copper-dependent manner. Interacts with ANK2; this interaction is required for localization at costameres. Interacts with N4BP2L1.</text>
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        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
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            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Stress fiber</location>
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        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the dynactin subunit 4 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003718836.1"/>
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        <property type="component" value="Chromosome 5"/>
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    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001725">
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="DCTN4"/>
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    <dbReference type="PANTHER" id="PTHR13034">
        <property type="entry name" value="DYNACTIN P62 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13034:SF2">
        <property type="entry name" value="DYNACTIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dynactin_p62"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="12"/>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="14">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
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        <location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
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        <source>
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        <source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00093507"/>
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    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA49300.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="652" mass="71269" checksum="A6B8985D22840370" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDZ8</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_00857</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718116.1">
        <property type="nucleotide sequence ID" value="XM_003718068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDZ8"/>
    <dbReference type="STRING" id="242507.G4NDZ8"/>
    <dbReference type="GeneID" id="2674372"/>
    <dbReference type="KEGG" id="mgr:MGG_00857"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00857"/>
    <dbReference type="eggNOG" id="ENOG502SK1Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064110_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDZ8"/>
    <dbReference type="OMA" id="GWLIWRV"/>
    <dbReference type="OrthoDB" id="5421757at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="351" mass="39689" checksum="1CC1E1DDC297DF84" modified="2011-12-14" version="1">MAPSSRTSKGKGSVSKKATAAGSIPKPYRKIPDSLSSFVEILDPEHVYVAHVDSKLPAFKRKIFLVPVALNLAVFSLFVLRLRYIAPYYKQLALAAAGNHVTGISLDTAALSWTALSWIIFRRGFTLFLDLVLLIFVWPWPVEFCLGRTHGNPCLWRWQVGFRDKEVYVRRSREWDRQLAGRDVLTDQAPRSQLATYVRNATSPVLLNDKTGYLTMNGDWDLDWAAMVYAHKLVDAKALALDEFRLVVLLHHKEHGWLVLDTGSGVSGGSKEDERRRQVFAFREALVGLGKEDLFFRWIETVQFEATQPGGMTEEKQVAVAQKIRDLFQDEGINFDELWRESVGSDSLAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEG8</accession>
    <name>G4NEG8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Citrate transporter-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_00109</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719029.1">
        <property type="nucleotide sequence ID" value="XM_003718981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEG8"/>
    <dbReference type="STRING" id="242507.G4NEG8"/>
    <dbReference type="GeneID" id="2674329"/>
    <dbReference type="KEGG" id="mgr:MGG_00109"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00109"/>
    <dbReference type="eggNOG" id="ENOG502QVIJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017834_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEG8"/>
    <dbReference type="OMA" id="HWVEKTG"/>
    <dbReference type="OrthoDB" id="442352at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43302">
        <property type="entry name" value="TRANSPORTER ARSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43302:SF5">
        <property type="entry name" value="TRANSPORTER ARSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="597"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="641"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="705"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="751"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="Citrate transporter-like" evidence="9">
        <location>
            <begin position="135"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="422"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="541"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="482"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="516"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="541"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA49445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="780" mass="86285" checksum="89DD181BBC23C6F9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEY3</accession>
    <name>G4NEY3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718293.1">
        <property type="nucleotide sequence ID" value="XM_003718245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEY3"/>
    <dbReference type="GeneID" id="12984061"/>
    <dbReference type="KEGG" id="mgr:MGG_17390"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17390"/>
    <dbReference type="HOGENOM" id="CLU_1015899_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEY3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="274" mass="29073" checksum="372418EC572CA97F" modified="2011-12-14" version="1">MQKSGTITFFFALFFHHSPLRPAPAGLRRAGGKLWVRHPTQAIIASVPPILPSTPPQLQLLTPSWRAQSLGHAGPLAHVIAKRSGAAAQALVVYRDPVAEACHFVLLGIGPNGGGRCRHRLLRSGACRRGARRREFTESNVAPARRRPTCLLACADAGVVGRNARDVLARDIQRHLVLRAAPQIPPIGAISDEIIVIARFVGPIFAEPVLQTIIQIAIGVNGGDARAERGFPPGPGSDRRWMRQECLDRGGSQNLAVRASVDDGGPGGGGGGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFG0</accession>
    <name>G4NFG0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secretory lipase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719555.1">
        <property type="nucleotide sequence ID" value="XM_003719507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFG0"/>
    <dbReference type="SMR" id="G4NFG0"/>
    <dbReference type="GeneID" id="2677176"/>
    <dbReference type="KEGG" id="mgr:MGG_04257"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04257"/>
    <dbReference type="eggNOG" id="ENOG502RPSG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029538_1_0_1"/>
    <dbReference type="InParanoid" id="G4NFG0"/>
    <dbReference type="OMA" id="VDWQKRF"/>
    <dbReference type="OrthoDB" id="5382058at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005152">
        <property type="entry name" value="Lipase_secreted"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34853:SF1">
        <property type="entry name" value="LIPASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025499798" description="Secretory lipase family protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="48413" checksum="F06675391F8192D9" modified="2011-12-14" version="1">MLTSTVFAIGAAALLGQAQVVVGQADINAVFRSAIATENWATADITNDPFYDLPSNFSRESSRPGDLLRWQDVPFRQLATNFTRIPRGMSLSRFVYVTEDKDRKPIPSSGYVLLPYSLPQGQEKFRTIAWAHGTAGNARKCAPSNNLQLDYAWQAPFLYASQGFAVVATDYAGLGVEIPSTFQYEAGDLHAADVAYSVVAARKVLGAHLTDEWVVAGHSEGGMTAWRTNERLARDGQEELLKAGKFLGAASIAPALQPIQLIPKEIQRAGPNGTLGINSVYVLQALEGIYPSIKLSDYVSDAVLSMMPLINQSCLLTGAALIGTLKASQVFKNTSWITGPEMQDWQKRINGAGPHKLAGPMMVVQGDIDTLTYPENNEADFDATCQAFPESSMEWLSVPQAAHETALEAGADRYVPWIKALFDGNVPAQGCTKSVLANFTNTFRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFK9</accession>
    <name>G4NFK9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7888 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719183.1">
        <property type="nucleotide sequence ID" value="XM_003719135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFK9"/>
    <dbReference type="GeneID" id="2679011"/>
    <dbReference type="KEGG" id="mgr:MGG_08789"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08789"/>
    <dbReference type="eggNOG" id="ENOG502SB2X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105121_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFK9"/>
    <dbReference type="OMA" id="ACYNKAF"/>
    <dbReference type="OrthoDB" id="3478218at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057210">
        <property type="entry name" value="DUF7888"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40845">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40845:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25411">
        <property type="entry name" value="DUF7888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466473" description="DUF7888 domain-containing protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7888" evidence="2">
        <location>
            <begin position="72"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="204" mass="21394" checksum="513B4DBE29890C85" modified="2011-12-14" version="1">MGHAKIHGTKSVKMRFTSAIVIALVGAAQASPIAAPEPVLNTVGLDVPIEARAILSGGEEAAVLDKRIEPITTSILVAAGSAAATAAVDAAVKAIGNAIKGLQNWDKAREEFTKKVTAEMWAKADKKAFSAAVCYNMGYDAPNIDGKTSVQIKSGLLKTSYDCFFMKAGANTFQAKGDGGFQNLAAQHDSRCTYDKKAVKLTCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFM6</accession>
    <name>G4NFM6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_08774</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719200.1">
        <property type="nucleotide sequence ID" value="XM_003719152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFM6"/>
    <dbReference type="SMR" id="G4NFM6"/>
    <dbReference type="FunCoup" id="G4NFM6">
        <property type="interactions" value="42"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NFM6"/>
    <dbReference type="GeneID" id="2678996"/>
    <dbReference type="KEGG" id="mgr:MGG_08774"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08774"/>
    <dbReference type="eggNOG" id="ENOG502QRIP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021264_13_1_1"/>
    <dbReference type="InParanoid" id="G4NFM6"/>
    <dbReference type="OMA" id="MEHYKAY"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF4">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466233" evidence="9">
        <location>
            <begin position="21"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="10">
        <location>
            <begin position="58"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="269"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="282"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA46833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="368" mass="38797" checksum="7CBF6B7D3BB3C637" modified="2011-12-14" version="1">MPSSTAAVFTVSLLATLAAASPLAEQQPAARLNPRAMARPKFGNVPYGQQLKSCVEPNMIALTFDDGPGQYTAHVLDLLERAGNLKATFFLNGKNGQNGMENSGLSSVLKRMVNAGHQLASHSYSHKNFDEISADEQEQELLLNEDAFARLIGMVPTYFRPPFTACGATCLATAGRLAYHVTDYDLDTKDYEGNLQASKNKFQEGMSQSPKSWVALAHDIHELTANSITPFMIDTAKSKGYKFVTMGECLGDPRENWYRDPSTGRAVAALGSSNNVKPPALVSSESSSTTASSTTATATSTSVSKPTSTPTPVRAGNSTTSNASSTRSAGSPASTSAAASKEGAADRVGFGGLFASLIWGATAFALLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFV0</accession>
    <name>G4NFV0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane adaptor Erv26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_08706</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SVP26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719274.1">
        <property type="nucleotide sequence ID" value="XM_003719226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFV0"/>
    <dbReference type="FunCoup" id="G4NFV0">
        <property type="interactions" value="248"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NFV0"/>
    <dbReference type="GeneID" id="2678931"/>
    <dbReference type="KEGG" id="mgr:MGG_08706"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08706"/>
    <dbReference type="eggNOG" id="KOG4136">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058268_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFV0"/>
    <dbReference type="OMA" id="TMGTEPV"/>
    <dbReference type="OrthoDB" id="28257at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097020">
        <property type="term" value="F:COPII receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007277">
        <property type="entry name" value="Svp26/Tex261"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13144:SF0">
        <property type="entry name" value="PROTEIN TEX261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13144">
        <property type="entry name" value="TEX261 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04148">
        <property type="entry name" value="Erv26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA46907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="24581" checksum="2DDD7C519D6062A5" modified="2011-12-14" version="1">MWILPLIGYLGTILGFAFLTLAIASGLYYLSELVEEHTVIAKRILQRMIYSIIVIQLLLCLVDKFPFFLSLLGVVSHVVYLGNLRRFPFVRLSDPLFLTSCILVIVNHYLWFRHFADRQHNAYQNMTSYYDTPSGVPTFSEIASYFGICVWLVPFSLFISLSASDNVLPTMGSETPSIGGGSDEAKRKGQGMAKALVDNIMALFAEIGAMGGSRRSDRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH87</accession>
    <name>G4NH87_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ima1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_12094</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719964.1">
        <property type="nucleotide sequence ID" value="XM_003719916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH87"/>
    <dbReference type="STRING" id="242507.G4NH87"/>
    <dbReference type="GeneID" id="2677485"/>
    <dbReference type="KEGG" id="mgr:MGG_12094"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12094"/>
    <dbReference type="eggNOG" id="KOG4623">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013127_0_0_1"/>
    <dbReference type="InParanoid" id="G4NH87"/>
    <dbReference type="OMA" id="MERRYPQ"/>
    <dbReference type="OrthoDB" id="5966927at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034506">
        <property type="term" value="C:chromosome, centromeric core domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034992">
        <property type="term" value="C:microtubule organizing center attachment site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071765">
        <property type="term" value="P:nuclear inner membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042321">
        <property type="entry name" value="Ima1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018617">
        <property type="entry name" value="Ima1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538:SF1">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09779">
        <property type="entry name" value="Ima1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="628"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="665"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="707"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="Ima1 N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="730" mass="82040" checksum="6EA60318F6EC70CA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHI7</accession>
    <name>G4NHI7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trichodiene oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_03828</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720064.1">
        <property type="nucleotide sequence ID" value="XM_003720016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHI7"/>
    <dbReference type="SMR" id="G4NHI7"/>
    <dbReference type="STRING" id="242507.G4NHI7"/>
    <dbReference type="GeneID" id="2677219"/>
    <dbReference type="KEGG" id="mgr:MGG_03828"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03828"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_4_1"/>
    <dbReference type="InParanoid" id="G4NHI7"/>
    <dbReference type="OMA" id="TSAITHY"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11062">
        <property type="entry name" value="CYP58-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF147">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA47697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="518" mass="58391" checksum="D10F1F0B52A68777" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI33</accession>
    <name>G4NI33_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cyclin-dependent kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_09363</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WHI5/NRM1 family.</text>
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        <property type="protein sequence ID" value="EHA47893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003720212.1"/>
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    <dbReference type="STRING" id="242507.G4NI33"/>
    <dbReference type="GeneID" id="2680425"/>
    <dbReference type="KEGG" id="mgr:MGG_09363"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09363"/>
    <dbReference type="eggNOG" id="ENOG502S25T">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_026594_0_0_1"/>
    <dbReference type="InParanoid" id="G4NI33"/>
    <dbReference type="OMA" id="TIHRRQG"/>
    <dbReference type="OrthoDB" id="2359117at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
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    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039198">
        <property type="entry name" value="Srl3/Whi5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013734">
        <property type="entry name" value="TF_Nrm1/Whi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28246">
        <property type="entry name" value="G1-SPECIFIC TRANSCRIPTIONAL REPRESSOR WHI5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28246:SF1">
        <property type="entry name" value="G1-SPECIFIC TRANSCRIPTIONAL REPRESSOR WHI5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08528">
        <property type="entry name" value="Whi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="202"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="281"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="454"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="585"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="335"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
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            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
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            <end position="417"/>
        </location>
    </feature>
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        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
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        <location>
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        <location>
            <begin position="531"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="585"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA47893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="64524" checksum="623E5DBF3C2891C3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI92</accession>
    <name>G4NI92_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_14930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720319.1">
        <property type="nucleotide sequence ID" value="XM_003720271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI92"/>
    <dbReference type="SMR" id="G4NI92"/>
    <dbReference type="STRING" id="242507.G4NI92"/>
    <dbReference type="GeneID" id="12987288"/>
    <dbReference type="KEGG" id="mgr:MGG_14930"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14930"/>
    <dbReference type="eggNOG" id="ENOG502QQ8N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022730_0_1_1"/>
    <dbReference type="InParanoid" id="G4NI92"/>
    <dbReference type="OMA" id="SCCNAGP"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF279">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="43"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="475" mass="51974" checksum="06BCC70E7C9FAFCD" modified="2011-12-14" version="1">MTDEQKIPPNRTPVHNPVPSFWTATTFPLSDHRTTPDLPTTSDIVVIGAGLAGVATAYHILKQHHGSTAEKPPPSVLILEARQICSGATGRNGGHIKPDVYFNVGKYASLYGMEAAAEMARFEAEHVYAVKDLIETEGLDCDFHLTRAVDVCLDADHARETEAAYRELVKAGVADLRDVDFTPKPDAERVSGIKGAQCCFSFTAAHLWPSKLVHQLLQRLIDQGGINVQSNTPVISIASKPDSEGRWTITTPRGNVAARNVVHATNAYAAHLLPEYTGRIVPVRGVCSRIVHPEGQHGSQHLVNTYGIRYSARDYDYLIPRADGSIVVGGARQMFWHKPELWFNNIRDDELVEEAGGYFDGYMQRTFRGWENSGATVDKVWTGIMGYSSDFMPHVGQVPGKDGQYIIAGFSGHGMPEILLASRGVAKMVCSGVSFEATGLPRLVETTAERISKERGSALEESLSSTLGDDHRILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIF3</accession>
    <name>G4NIF3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">transketolase</fullName>
            <ecNumber evidence="5">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_09856</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the transketolase family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720380.1">
        <property type="nucleotide sequence ID" value="XM_003720332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIF3"/>
    <dbReference type="SMR" id="G4NIF3"/>
    <dbReference type="STRING" id="242507.G4NIF3"/>
    <dbReference type="GeneID" id="2680813"/>
    <dbReference type="KEGG" id="mgr:MGG_09856"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09856"/>
    <dbReference type="eggNOG" id="KOG0523">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009227_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIF3"/>
    <dbReference type="OMA" id="HTWCMVG"/>
    <dbReference type="OrthoDB" id="10267175at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000004">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000012">
        <property type="entry name" value="Transketolase, variant 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF6">
        <property type="entry name" value="TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="11">
        <location>
            <begin position="380"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA48013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="717" mass="78294" checksum="9010988480DEB063" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIH2</accession>
    <name>G4NIH2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetylxylan esterase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_09840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720399.1">
        <property type="nucleotide sequence ID" value="XM_003720351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIH2"/>
    <dbReference type="SMR" id="G4NIH2"/>
    <dbReference type="ESTHER" id="mago7-g4nih2">
        <property type="family name" value="Acetylxylan_esterase"/>
    </dbReference>
    <dbReference type="GeneID" id="2680839"/>
    <dbReference type="KEGG" id="mgr:MGG_09840"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09840"/>
    <dbReference type="eggNOG" id="ENOG502SQ4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040058_4_1_1"/>
    <dbReference type="InParanoid" id="G4NIH2"/>
    <dbReference type="OMA" id="PRHVPGK"/>
    <dbReference type="OrthoDB" id="2586582at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF9">
        <property type="entry name" value="CUTINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466985" evidence="4">
        <location>
            <begin position="18"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA48032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="299" mass="30583" checksum="B154D07071F02180" modified="2011-12-14" version="1">MVSALPIAGLLVAAVAAQTPDASLAPPTSCAPGVQIFAARGTTEAPGVGKIQTVAGNVTAAIPGSAVTAVDYPATFDDYAQSVATGSSDLGQLVKDYVKMCPDSKVALLGYSQGAQAVADLICGASSELMPVKTADLDSIYDKNIIAMILFGDPTRAANQSFNLGTVTDRDGLFPRLKNDACEPYSPRLRSWCDVADRYCDPSAPGGIDTTVHGTYFNKYTQAAKDFIVEQWQLSQKSLPPRSSIGSAQPTGTANGTHPAHPTGAPVPTSTTPVAAGASRTGAAAFGAILMAGVAAFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIK3</accession>
    <name>G4NIK3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003720382.1"/>
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    <dbReference type="KEGG" id="mgr:MGG_09810"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09810"/>
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        <property type="entry name" value="Heat-Labile Enterotoxin, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466602" evidence="1">
        <location>
            <begin position="23"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="239" mass="26844" checksum="F25A7A1BF0C049A6" modified="2011-12-14" version="1">MYGSTIALGFGLVSAIIGAAGAASVPNIVYRGDHRSPAIIHKQGGFFARGYAVGVEPDPKFPYHKHVEHNPFDPENLKSPFLSVSSRRDIAQFHIRHYMPENNKNYVYVYHINTTGVVKQYYHDVNALYAEDEVEHTFSYENEFLSDHPILWRAITGWDVVNPQGVIKETVTVENLMHMIASTRGGTPVTPEKVQRILDWAYVAYNGLDELKKATEEKLAKEKAGGQRGAARHVQPQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIY0</accession>
    <name>G4NIY0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WH1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02802</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720939.1">
        <property type="nucleotide sequence ID" value="XM_003720891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIY0"/>
    <dbReference type="SMR" id="G4NIY0"/>
    <dbReference type="STRING" id="242507.G4NIY0"/>
    <dbReference type="GeneID" id="2682355"/>
    <dbReference type="KEGG" id="mgr:MGG_02802"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02802"/>
    <dbReference type="eggNOG" id="KOG3671">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_015385_1_1_1"/>
    <dbReference type="InParanoid" id="G4NIY0"/>
    <dbReference type="OrthoDB" id="8963340at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0003779">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045010">
        <property type="term" value="P:actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01205">
        <property type="entry name" value="EVH1_WASP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000281">
        <property type="entry name" value="Actin associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033927">
        <property type="entry name" value="WASPfam_EVH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000697">
        <property type="entry name" value="WH1/EVH1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00568">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00461">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50229">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH1" evidence="3">
        <location>
            <begin position="17"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="568" mass="62220" checksum="E9DC33E0D810A52E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJ80</accession>
    <name>G4NJ80_PYRO7</name>
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        <recommendedName>
            <fullName evidence="10">Cenp-O kinetochore centromere component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_12605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-O/MCM21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46296.1"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="CENTROMERE PROTEIN O"/>
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        <property type="entry name" value="INNER KINETOCHORE SUBUNIT MAL2"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA46296.1"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="36998" checksum="3251E3CF9AE72574" modified="2011-12-14" version="1">MPTALDNELESLRKRAEHLRAEVKLRASTLLLNPVAATQLLDEQPAQAAAPALLLPTPPSKSRSKSSSNAPLGPKQRDLLKKRRAKQAAHDQRNTYRTCAGITTFKVRDPDPAAVDGGAVLGVRIEVMRSGRFMRPFYVLLNRPWDKDAAAKRYLRVHRHTLPAAIPLAGLAARYLPAPRSASSGKRPRQDLGAFVRRLRRELVRYHQRLGAVADLRAVVGLDDRSKAPVGTPADEPPEAVVMKSIEDDRESRARQRRAVAGIVDIEPVDTAATQFRFDWRDGRVGRLVIGPGGEVLQSVVVLPDGGRDRVTQQDVFGDCARIEDVVTKLRGPLGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJE7</accession>
    <name>G4NJE7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721104.1">
        <property type="nucleotide sequence ID" value="XM_003721056.1"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NJE7"/>
    <dbReference type="GeneID" id="2682801"/>
    <dbReference type="KEGG" id="mgr:MGG_02670"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02670"/>
    <dbReference type="eggNOG" id="ENOG502QPW5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_241343_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJE7"/>
    <dbReference type="OMA" id="GSHIENP"/>
    <dbReference type="OrthoDB" id="3941926at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="308"/>
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        </location>
    </feature>
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        <location>
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        </location>
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        <location>
            <begin position="1042"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="673"/>
            <end position="684"/>
        </location>
    </feature>
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        <location>
            <begin position="685"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="866"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="962"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1076"/>
        </location>
    </feature>
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        <location>
            <begin position="1108"/>
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        </location>
    </feature>
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        <location>
            <begin position="1146"/>
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        </location>
    </feature>
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        <location>
            <begin position="1166"/>
            <end position="1177"/>
        </location>
    </feature>
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        <location>
            <begin position="1213"/>
            <end position="1227"/>
        </location>
    </feature>
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        <location>
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        </location>
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        <location>
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        </location>
    </feature>
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        </location>
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        <location>
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            <end position="1353"/>
        </location>
    </feature>
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        <location>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="1460"/>
            <end position="1472"/>
        </location>
    </feature>
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        <location>
            <begin position="1497"/>
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        </location>
    </feature>
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        </location>
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        <location>
            <begin position="1552"/>
            <end position="1563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1685" mass="181909" checksum="FFC4C79B603DA78F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKY6</accession>
    <name>G4NKY6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_09668</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721421.1">
        <property type="nucleotide sequence ID" value="XM_003721373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKY6"/>
    <dbReference type="SMR" id="G4NKY6"/>
    <dbReference type="STRING" id="242507.G4NKY6"/>
    <dbReference type="ESTHER" id="mago7-g4nky6">
        <property type="family name" value="Fungal_carboxylesterase_lipase"/>
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    <dbReference type="GeneID" id="2680575"/>
    <dbReference type="KEGG" id="mgr:MGG_09668"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09668"/>
    <dbReference type="eggNOG" id="KOG1516">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006586_15_2_1"/>
    <dbReference type="InParanoid" id="G4NKY6"/>
    <dbReference type="OMA" id="RSQPVFQ"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005132175" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="23"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="38"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="397"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA46678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="534" mass="56759" checksum="E83CEF854FF3859D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL35</accession>
    <name>G4NL35_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_12548</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720711.1">
        <property type="nucleotide sequence ID" value="XM_003720663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL35"/>
    <dbReference type="GeneID" id="5050431"/>
    <dbReference type="KEGG" id="mgr:MGG_12548"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12548"/>
    <dbReference type="eggNOG" id="ENOG502SIM5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057368_0_0_1"/>
    <dbReference type="InParanoid" id="G4NL35"/>
    <dbReference type="OMA" id="LIIQQHM"/>
    <dbReference type="OrthoDB" id="5378633at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF114">
        <property type="entry name" value="MEMBRANE PROTEIN PTH11-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06620)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="25"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA45968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="352" mass="39015" checksum="2301AA2CE80D2436" modified="2011-12-14" version="1">MSPPGLDQVIAWHICTYTAVCFVVARIAIRLRRVKNLRTDDGFIVLAVLCLVGDLAIQHYMWTQGLADPGGSSFDNFTNIMKMIVPGSTLYITSLWAVKAALVVLYKRIAGPRSSMQVVCNVALGVLAATWLLIFFHIMFQCWPHDKRWSQNPNYQCDPHNSEINYWITVIINITTDVAIISLPVSIVAGLQMKLRKKIGVGAIFMLGIFVIIGSIIRAYFSKRDEIMLTCTVSMIETMIAIIAACLPPLLSIVSQKLTTKKTGYNAEQHQSHELSSHMATHTQRSAYSTTRIEATTTKFLQQQKSSHLRGGDSEDELVGGVGAPHTSWLSTKPEPGGIHVTKTVETWRDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLA8</accession>
    <name>G4NLA8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720735.1">
        <property type="nucleotide sequence ID" value="XM_003720687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLA8"/>
    <dbReference type="GeneID" id="12984773"/>
    <dbReference type="KEGG" id="mgr:MGG_14994"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14994"/>
    <dbReference type="HOGENOM" id="CLU_2237135_0_0_1"/>
    <dbReference type="InParanoid" id="G4NLA8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA45992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="105" mass="11449" checksum="B58343D790D7D1AF" modified="2011-12-14" version="1">MFAPYRGHSVLTDNNSPPVLLRPTEPHDVCIASLCPSDPIFVSSIQRPRSELGINATTIILVSNHLLGYVKRTALLKRERLVACRSVTCLMKDGIEGSICSGACR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLK5</accession>
    <name>G4NLK5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720801.1">
        <property type="nucleotide sequence ID" value="XM_003720753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLK5"/>
    <dbReference type="SMR" id="G4NLK5"/>
    <dbReference type="GeneID" id="2682471"/>
    <dbReference type="KEGG" id="mgr:MGG_02918"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02918"/>
    <dbReference type="eggNOG" id="ENOG502RQ58">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_183952_0_0_1"/>
    <dbReference type="InParanoid" id="G4NLK5"/>
    <dbReference type="OMA" id="NCQSIDV"/>
    <dbReference type="OrthoDB" id="5401396at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.20.10">
        <property type="entry name" value="Crystallins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011024">
        <property type="entry name" value="G_crystallin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49695">
        <property type="entry name" value="gamma-Crystallin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466747" evidence="1">
        <location>
            <begin position="23"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="114" mass="12580" checksum="2F910176BAA4DC3F" modified="2011-12-14" version="1">MKTFQILSAVAISLLFGGAANAAVIAGRQDQITIKLCPHENMDGDCWFIDVNDCTNVEEHMNDLVSSFDTGERTCSFFERENCGGHSYTARGERKTLPKDFNDQISSVKCNKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLL3</accession>
    <name>G4NLL3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pigment biosynthesis protein Ayg1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720809.1">
        <property type="nucleotide sequence ID" value="XM_003720761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLL3"/>
    <dbReference type="SMR" id="G4NLL3"/>
    <dbReference type="STRING" id="242507.G4NLL3"/>
    <dbReference type="GeneID" id="12984801"/>
    <dbReference type="KEGG" id="mgr:MGG_17928"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17928"/>
    <dbReference type="eggNOG" id="ENOG502S29V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053723_1_0_1"/>
    <dbReference type="InParanoid" id="G4NLL3"/>
    <dbReference type="OMA" id="NDHEYPF"/>
    <dbReference type="OrthoDB" id="5409895at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000145">
        <property type="entry name" value="Pigment biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010520">
        <property type="entry name" value="FrsA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050261">
        <property type="entry name" value="FrsA_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946:SF12">
        <property type="entry name" value="CONIDIAL PIGMENT BIOSYNTHESIS PROTEIN AYG1 (AFU_ORTHOLOGUE AFUA_2G17550)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22946">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06500">
        <property type="entry name" value="FrsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="47250" checksum="B8D1A69521DFC3B2" modified="2011-12-14" version="1">MSPHKLMETDNAQPTKGRHWIMGAEAFERRMPHHDGIKALWETKWKFPCTKSLYPFHDGKYEDFEPIFTHLIANDINDGTSPEYTRAFFPIAEALVARADAATAGSAEATELYLRACAVYRIARFPYITAYPRVNCPVKWEAWEAQKAAYLRCGRAWAEPVQEAMVAHTHRKGNDRDSIPVYVRVPKTTAESGGPCPAVILMTGLDGYRPDNTVRCDEFLARGWGVVVVEIPGTADCPADSADPESPDRLWSSLLDWMTALKVFDMRRILVWGLSSGGYYAIRIAHTHKDRLVGSIAQGAGCHYFYDRDWLEKADGHEYPFKLTPAMAMKHGYESVEECKEGVQKKFSLLETGIINMPSTRLLLVNGTLDGLMPIEDSMMLFEYGSPKEARFFTDALHMGYPLANGAVYPWMESVMASVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLM7</accession>
    <name>G4NLM7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720823.1">
        <property type="nucleotide sequence ID" value="XM_003720775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLM7"/>
    <dbReference type="SMR" id="G4NLM7"/>
    <dbReference type="FunCoup" id="G4NLM7">
        <property type="interactions" value="326"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NLM7"/>
    <dbReference type="GeneID" id="12984810"/>
    <dbReference type="KEGG" id="mgr:MGG_17936"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17936"/>
    <dbReference type="eggNOG" id="KOG2741">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023194_25_2_1"/>
    <dbReference type="InParanoid" id="G4NLM7"/>
    <dbReference type="OMA" id="GEWGIQH"/>
    <dbReference type="OrthoDB" id="446809at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055080">
        <property type="entry name" value="Gal80p-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051317">
        <property type="entry name" value="Gfo/Idh/MocA_oxidoreduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708">
        <property type="entry name" value="CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43708:SF1">
        <property type="entry name" value="GALACTOSE_LACTOSE METABOLISM REGULATORY PROTEIN GAL80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22685">
        <property type="entry name" value="Gal80p_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Gal80p-like C-terminal" evidence="2">
        <location>
            <begin position="145"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="375" mass="40446" checksum="54D33D7B36A79E11" modified="2011-12-14" version="1">MPELPKPIRVGILGLSATGSWSVASHLPALLSLPESYAIVAVCNSSEASSQAAIKAYNLPVATKAYGSPEQLADDPDVDLVVSSTNVVLHKQALLPSIRKGKAVFCEWPLGRNLAEAQELLDEIKRRNDGDVSRTVIGLQGRYSPVVKKLSEILSSGRVGKLQRTSFSAPAGYCGDEGLEEHEYFFREADGGNLVSIFFLHIIESVLFGLGGREFAHLDAVLGGVGGEVQLKNKSGDVVRTMVRETHKSVAIQGVLDDGSELSLQLWGGKGAPGDKESTYWRVVGDKGEVRVRGTGPNLQMGGDEVSMSVLDYASGEEEVVALAAEELKPVPANNVARLYAKFAEGRAGEYPDWEWAVKRHMLIDQIYKKNAARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH17</accession>
    <name>G5EH17_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF718 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g249</name>
        <name evidence="3" type="ORF">MGG_12671</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721266.1">
        <property type="nucleotide sequence ID" value="XM_003721218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH17"/>
    <dbReference type="SMR" id="G5EH17"/>
    <dbReference type="STRING" id="242507.G5EH17"/>
    <dbReference type="GeneID" id="5050543"/>
    <dbReference type="KEGG" id="mgr:MGG_12671"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12671"/>
    <dbReference type="eggNOG" id="ENOG502S4QF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100689_1_0_1"/>
    <dbReference type="OMA" id="HAKVWPE"/>
    <dbReference type="OrthoDB" id="9981546at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016857">
        <property type="term" value="F:racemase and epimerase activity, acting on carbohydrates and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008000">
        <property type="entry name" value="Rham/fucose_mutarotase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34389">
        <property type="entry name" value="L-RHAMNOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34389:SF2">
        <property type="entry name" value="L-RHAMNOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05336">
        <property type="entry name" value="rhaM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="17292" checksum="21F963E8CDFB8A89" modified="2011-12-14" version="1">MWTKPKLSPTTNETPTGADPLSPTVLSSRQRNPGRRFAQIVKLKPEFQEQYKEAHAKVWPDVLKQIKECNIVDYSIFHDPQTNILFASFKYIGYDYQGDMEKMRENEKVREWWKMTDGWQESMVPGAKSSEAGEPGWWKPVEEVFYTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHS6</accession>
    <name>G5EHS6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspergillopepsin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g198</name>
        <name evidence="3" type="ORF">MGG_09032</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721304.1">
        <property type="nucleotide sequence ID" value="XM_003721256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHS6"/>
    <dbReference type="SMR" id="G5EHS6"/>
    <dbReference type="STRING" id="242507.G5EHS6"/>
    <dbReference type="GeneID" id="2680148"/>
    <dbReference type="KEGG" id="mgr:MGG_09032"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09032"/>
    <dbReference type="eggNOG" id="ENOG502RJF6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066466_0_1_1"/>
    <dbReference type="OMA" id="WSGAVIT"/>
    <dbReference type="OrthoDB" id="2862635at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070007">
        <property type="term" value="F:glutamic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13426">
        <property type="entry name" value="Peptidase_G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.700">
        <property type="entry name" value="Peptidase G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000250">
        <property type="entry name" value="Peptidase_G1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038656">
        <property type="entry name" value="Peptidase_G1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536:SF1">
        <property type="entry name" value="ASPERGILLOPEPSIN, PUTAITVE (AFU_ORTHOLOGUE AFUA_7G01200)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37536">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02970)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01828">
        <property type="entry name" value="Peptidase_A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00977">
        <property type="entry name" value="SCYTLDPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600250-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ70791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="290" mass="30581" checksum="A86C296046B7E2DF" modified="2011-12-14" version="1">MKATLVTALVGATAVNATSFRPAATQQHARPQSQVFDRSLHRADPVAVAGSNSRVFAASVMSTAAAAEKPPVVGGAYLSSSEITSVGGRFTVPRATQPTKGAIAGQDIEYGASFWVGIDGVNCTTGTLRAGIDIFWSSRGESYHAWYQVSADSSKDFLAGEIDVAPGDELHVTATASGGNGTLVVNNRSTNQTVERHLAPGEKLCRSEAAWLIEDFVLVQAIGAPVALVNFTDVTFGDMKTTMQCGSSERAEPVNLDDVKVMDVEVEEQGGKLTDCQMTGVDQMTCKRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHT6</accession>
    <name>G5EHT6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGCH7_ch7g637</name>
        <name evidence="6" type="ORF">MGG_02878</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15</strain>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">70-15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720853.1">
        <property type="nucleotide sequence ID" value="XM_003720805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHT6"/>
    <dbReference type="SMR" id="G5EHT6"/>
    <dbReference type="STRING" id="242507.G5EHT6"/>
    <dbReference type="GeneID" id="2682431"/>
    <dbReference type="KEGG" id="mgr:MGG_02878"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02878"/>
    <dbReference type="eggNOG" id="KOG3872">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021864_0_0_1"/>
    <dbReference type="OMA" id="VEHAGFM"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="CDD" id="cd22679">
        <property type="entry name" value="FHA_SLMAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000127">
        <property type="entry name" value="Uncharacterized protein C3H7.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051176">
        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715:SF37">
        <property type="entry name" value="LD47843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="776"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="4">
        <location>
            <begin position="185"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="427"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="556"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="628"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="484"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="628"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="655"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="700"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="716"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="756"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EAQ71230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA46110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="807" mass="86969" checksum="AE22D37A439DDA7F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHW6</accession>
    <name>G5EHW6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGCH7_ch7g881</name>
        <name evidence="4" type="ORF">MGG_03078</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15</strain>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720595.1">
        <property type="nucleotide sequence ID" value="XM_003720547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHW6"/>
    <dbReference type="GeneID" id="2682631"/>
    <dbReference type="KEGG" id="mgr:MGG_03078"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03078"/>
    <dbReference type="eggNOG" id="ENOG502S450">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073105_0_0_1"/>
    <dbReference type="OMA" id="NGSTWRN"/>
    <dbReference type="OrthoDB" id="3467153at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834279" evidence="2">
        <location>
            <begin position="22"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EAQ71474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA45852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="319" mass="34895" checksum="BD3A3B5B00099DBA" modified="2011-12-14" version="1">MAPTQILLTLALAILSPLTTATPTPPAQDPSLAQFEEHFVNSLPYTSDNATTLRLVGFKRMALPAADVAAFEEAWNAPPSEWRRRRDGGSAAGRHEQHFWYDRARREVRVYFPVEGALLRRSAVEEGGNVFVEADGLGQVVGVGEVVKRDVDGEGRARAVVGRRATDQVSGVEGNVIRDGIIYLETPALPVRHLDGRTTIYDFGVKSLDHDSHSHDHDHDHEVEADQGQGGANLAKRAEGKKGCLENHKGKNCSKAYGINQGRCPMNPDTCMDYNGWKTDCKKGTTTKFGIPTLSKAVKFLGSDCSVSMARGHCWNEVM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-08-16" modified="2025-06-18" version="90" xmlns="https://uniprot.org/uniprot">
    <accession>Q51Y68</accession>
    <accession>A4RAJ2</accession>
    <accession>G4N3B8</accession>
    <name>ATG17_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Autophagy-related protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">ATG17</name>
        <name type="ORF">MGG_07667</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711603.1">
        <property type="nucleotide sequence ID" value="XM_003711555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q51Y68"/>
    <dbReference type="SMR" id="Q51Y68"/>
    <dbReference type="FunCoup" id="Q51Y68">
        <property type="interactions" value="138"/>
    </dbReference>
    <dbReference type="STRING" id="242507.Q51Y68"/>
    <dbReference type="EnsemblFungi" id="MGG_07667T0">
        <property type="protein sequence ID" value="MGG_07667T0"/>
        <property type="gene ID" value="MGG_07667"/>
    </dbReference>
    <dbReference type="GeneID" id="2683587"/>
    <dbReference type="KEGG" id="mgr:MGG_07667"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07667"/>
    <dbReference type="eggNOG" id="ENOG502SAME">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028356_0_0_1"/>
    <dbReference type="InParanoid" id="Q51Y68"/>
    <dbReference type="OMA" id="THVWRAN"/>
    <dbReference type="OrthoDB" id="1937984at2759"/>
    <dbReference type="PHI-base" id="PHI:11535"/>
    <dbReference type="PHI-base" id="PHI:2083"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007240">
        <property type="entry name" value="Atg17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045326">
        <property type="entry name" value="ATG17-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28005">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28005:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04108">
        <property type="entry name" value="ATG17_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0072">Autophagy</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000124562" description="Autophagy-related protein 17">
        <location>
            <begin position="1"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="504" mass="55292" checksum="A37E8F86242E30FB" modified="2005-06-07" version="1">MPSSSSARSSQSLRSSAAAAVSTSSGAADQPSVPIEILVEHLLAAKRSLSSMTLVLEANDLTTQARSVHEDSVVLAARTAFLRAGIAQQIHTLERIRRGLARTYDVGRRDFEQLIKVLDDAGERLTRTMNVLHNTIVDPVFRPAGEEPRSLMFFVDEGNVDRLTKSLKESIAELKAAETSYDGDLLRFDNDIRSVKKHLLAAPGLPSPSNSVFSRPMADLVRTLTNHSHAMAENLSSLTRHFDLCVTAVRASEGGAALALRKAAEDGPSTISISGVIRGDGTDADDQDIKTMSARERDEMLRVVMQDATEVGEVVRDINSGLEEMQALGALVEQQAAHVRTAHECTLDAFRRLEEVEARLGSYVAAEREYVDRCEVEKDAIHERLAQAEDLVVFYEGYAGAYDGLVLEYERRRNVEDKIRALWRKAAAAVEKLEEQDAAARDSMRKDVGDYIPGDLWVGMDDPVRKWKVVAVDEGEGGSGEIEGSSVRLKKGTVEAARERVHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4G4</accession>
    <name>A0A151V4G4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2EXR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845960.1">
        <property type="nucleotide sequence ID" value="XM_016990536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4G4"/>
    <dbReference type="STRING" id="242507.A0A151V4G4"/>
    <dbReference type="GeneID" id="5050389"/>
    <dbReference type="KEGG" id="mgr:MGG_12501"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12501"/>
    <dbReference type="eggNOG" id="ENOG502RPDK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4G4"/>
    <dbReference type="OMA" id="SATFFDW"/>
    <dbReference type="OrthoDB" id="3469466at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045518">
        <property type="entry name" value="2EXR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20150">
        <property type="entry name" value="2EXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2EXR" evidence="1">
        <location>
            <begin position="21"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KYQ30456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="457" mass="53379" checksum="C3941A341EC28AFA" modified="2016-06-08" version="1">MTKRELFNDVYFQSQSCDSVFSKFPYLPRELRQMIWSHSLRRRRWIPLRVVLPTDYLSYVDYGQSREKYLRTPYYGARNSLGKIISGWDYHLAVDKEDSTLSPLFGVSSEARQIALEFYRVRVPVRQCLSLSSGRDLRLNPEYDVVFLKWAYRSYLIADILHDIKAHDPQDVGVVHLALNEGFCDYLDKLSCESPDGFPDIKYGLSLSTLHQVARESLAEMVRSKIQSIFYMVNFLWDRVWNPVAGISHPLTGTPGSGLFMLHHARGRPLDRHLDSATFFDWLPRDPRPVDADLGMVRLWDDPHRLSEWWTRLEALFGADGWWQTHPRPDFYLCPSTRWSTRFHGYEPCVGGDQADPDLTRERLELYLDDEARRLDEACEYAAVCHQWKGGRRGFLLDQATYERLQVELRDVVGMWVLRPDAYVDHENRTDPLERPKRCYDVSAAWPGLVVFEKAVD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-07-24" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>A4QUF0</accession>
    <accession>G4N1R5</accession>
    <name>PABP_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Polyadenylate-binding protein, cytoplasmic and nuclear</fullName>
            <shortName>PABP</shortName>
            <shortName>Poly(A)-binding protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName>Polyadenylate tail-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">PAB1</name>
        <name type="ORF">MGG_09505</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712237.1">
        <property type="nucleotide sequence ID" value="XM_003712189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4QUF0"/>
    <dbReference type="SMR" id="A4QUF0"/>
    <dbReference type="FunCoup" id="A4QUF0">
        <property type="interactions" value="1264"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4QUF0"/>
    <dbReference type="EnsemblFungi" id="MGG_09505T0">
        <property type="protein sequence ID" value="MGG_09505T0"/>
        <property type="gene ID" value="MGG_09505"/>
    </dbReference>
    <dbReference type="GeneID" id="2680542"/>
    <dbReference type="KEGG" id="mgr:MGG_09505"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09505"/>
    <dbReference type="eggNOG" id="KOG0123">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012062_22_4_1"/>
    <dbReference type="InParanoid" id="A4QUF0"/>
    <dbReference type="OMA" id="QQPGFMP"/>
    <dbReference type="OrthoDB" id="19742at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12378">
        <property type="entry name" value="RRM1_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12379">
        <property type="entry name" value="RRM2_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12380">
        <property type="entry name" value="RRM3_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000003">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000355">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000384">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006515">
        <property type="entry name" value="PABP_1234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034364">
        <property type="entry name" value="PABP_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045305">
        <property type="entry name" value="RRM2_I_PABPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01628">
        <property type="entry name" value="PABP-1234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0509">mRNA transport</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0810">Translation regulation</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000295394" description="Polyadenylate-binding protein, cytoplasmic and nuclear">
        <location>
            <begin position="1"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="RRM 1" evidence="2">
        <location>
            <begin position="61"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="RRM 2" evidence="2">
        <location>
            <begin position="149"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="RRM 3" evidence="2">
        <location>
            <begin position="242"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="RRM 4" evidence="2">
        <location>
            <begin position="346"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="3">
        <location>
            <begin position="664"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="376"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="596"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="740"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="389"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="600"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="645"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="753"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="762" mass="81934" checksum="4E1B393FB764A040" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKG4</accession>
    <name>G4MKG4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_10551</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710165.1">
        <property type="nucleotide sequence ID" value="XM_003710117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKG4"/>
    <dbReference type="STRING" id="242507.G4MKG4"/>
    <dbReference type="GeneID" id="2682157"/>
    <dbReference type="KEGG" id="mgr:MGG_10551"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10551"/>
    <dbReference type="HOGENOM" id="CLU_1586813_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKG4"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="18305" checksum="833A007176662268" modified="2011-12-14" version="1">MSSISSMPEESHIVLGPKHLRILVLGETGARKLSFIRLATGCDAQVGDGANPCTLLCTNYIGESGRSELIDTPGFDDLFKSNHEILAQISHTMWDVAALGPEALSHNRARVSGFIAAGTVFGELLNSGAIHQELWADNQDSDRKILAFFENSPHPMLTIQRELHSQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKK0</accession>
    <name>G4MKK0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA mismatch repair protein mutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_04466</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710995.1">
        <property type="nucleotide sequence ID" value="XM_003710947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKK0"/>
    <dbReference type="SMR" id="G4MKK0"/>
    <dbReference type="FunCoup" id="G4MKK0">
        <property type="interactions" value="23"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKK0"/>
    <dbReference type="GeneID" id="2678164"/>
    <dbReference type="KEGG" id="mgr:MGG_04466"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04466"/>
    <dbReference type="eggNOG" id="ENOG502QUUG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002472_4_0_1"/>
    <dbReference type="InParanoid" id="G4MKK0"/>
    <dbReference type="OMA" id="DTWIMRR"/>
    <dbReference type="OrthoDB" id="2534523at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043504">
        <property type="term" value="P:mitochondrial DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001238">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000042">
        <property type="entry name" value="DNA mismatch repair protein Msh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF34">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="7">
        <location>
            <begin position="705"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA58383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="829" mass="90910" checksum="22F969DF3AAAD394" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKQ0</accession>
    <name>G4MKQ0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709352.1">
        <property type="nucleotide sequence ID" value="XM_003709304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKQ0"/>
    <dbReference type="SMR" id="G4MKQ0"/>
    <dbReference type="GeneID" id="2684819"/>
    <dbReference type="KEGG" id="mgr:MGG_06646"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06646"/>
    <dbReference type="eggNOG" id="ENOG502SCEJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076635_1_0_1"/>
    <dbReference type="InParanoid" id="G4MKQ0"/>
    <dbReference type="OMA" id="RDWKPNG"/>
    <dbReference type="OrthoDB" id="5408734at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="188" mass="20646" checksum="BF4063E6B4DD9E2D" modified="2011-12-14" version="1">MASITNNPQAADNSSTVLSDEELDRDWKPNGRRPHSTIARSFSAELMDIFRIENSLADLDSQVDKRKQELSSRTTELESLEQRIKEMEARLRQRGSPPNSTGPAANSASPRHVRSPISGVFDESAQSSSDGSNKHQDDEARRHESRAAGEKYAGSRPGTARASRQAVPGALPPTPTESEDGDRERDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML12</accession>
    <name>G4ML12_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">alpha-glucosidase</fullName>
            <ecNumber evidence="5">3.2.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glucosidase II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_08623</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; N-glycan metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="5"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711051.1">
        <property type="nucleotide sequence ID" value="XM_003711003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML12"/>
    <dbReference type="SMR" id="G4ML12"/>
    <dbReference type="FunCoup" id="G4ML12">
        <property type="interactions" value="947"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ML12"/>
    <dbReference type="CAZy" id="GH31">
        <property type="family name" value="Glycoside Hydrolase Family 31"/>
    </dbReference>
    <dbReference type="GeneID" id="2679052"/>
    <dbReference type="KEGG" id="mgr:MGG_08623"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08623"/>
    <dbReference type="eggNOG" id="KOG1066">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000631_7_0_1"/>
    <dbReference type="InParanoid" id="G4ML12"/>
    <dbReference type="OMA" id="TVHQPLW"/>
    <dbReference type="OrthoDB" id="3237269at2759"/>
    <dbReference type="PHI-base" id="PHI:6739"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:Glc2Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="F:glucan 1,3-alpha-glucosidase activity"/>
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        <property type="project" value="EnsemblFungi"/>
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        <property type="term" value="P:fungal-type cell wall beta-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd06603">
        <property type="entry name" value="GH31_GANC_GANAB_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF54">
        <property type="entry name" value="BCDNA.GH04962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465768" description="alpha-glucosidase" evidence="14">
        <location>
            <begin position="25"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="16">
        <location>
            <begin position="90"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="15">
        <location>
            <begin position="394"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="17">
        <location>
            <begin position="731"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="205"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA58439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="980" mass="110691" checksum="9652CF09A1664C89" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML53</accession>
    <name>G4ML53_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-classical export protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709401.1">
        <property type="nucleotide sequence ID" value="XM_003709353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML53"/>
    <dbReference type="GeneID" id="5051539"/>
    <dbReference type="KEGG" id="mgr:MGG_14582"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14582"/>
    <dbReference type="eggNOG" id="ENOG502SD8V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_202020_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML53"/>
    <dbReference type="OMA" id="RRITMVF"/>
    <dbReference type="OrthoDB" id="2155101at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024242">
        <property type="entry name" value="NCE101"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11654">
        <property type="entry name" value="NCE101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="60" mass="6762" checksum="3C9E744AA9132BB0" modified="2011-12-14" version="1">MPPPTYIISRVADPVFAVFIGLSAAVTRVRREEKEKGRTSAETMDAFKRRLRYTVGMSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML57</accession>
    <name>G4ML57_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_06696</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709405.1">
        <property type="nucleotide sequence ID" value="XM_003709357.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4ML57"/>
    <dbReference type="GeneID" id="2684869"/>
    <dbReference type="KEGG" id="mgr:MGG_06696"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06696"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001037_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML57"/>
    <dbReference type="OMA" id="QLPGYTW"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Sensor histidine kinase/response regulator, putative"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
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        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="AAA_16"/>
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    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
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    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
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    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
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    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
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    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
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    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
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        <property type="entry name" value="HisK_dim/P_sf"/>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
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    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
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    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
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    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
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        <property type="entry name" value="HISTIDINE KINASE_RESPONSE REGULATOR, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12550)-RELATED"/>
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        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
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        <property type="entry name" value="Response_reg"/>
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        <property type="entry name" value="BCTRLSENSOR"/>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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        <property type="entry name" value="TPR-like"/>
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        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
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    </dbReference>
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 13" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="137"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="17">
        <location>
            <begin position="1986"/>
            <end position="2211"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="18">
        <location>
            <begin position="2279"/>
            <end position="2403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="737"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="2409"/>
            <end position="2580"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="1945"/>
            <end position="1976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="749"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="2416"/>
            <end position="2427"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="2443"/>
            <end position="2459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="2481"/>
            <end position="2492"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="2536"/>
            <end position="2548"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="2557"/>
            <end position="2568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="2569"/>
            <end position="2580"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="13">
        <location>
            <position position="2334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
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    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
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    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
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    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA56793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="2580" mass="285136" checksum="C04F9EE60AE55080" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML66</accession>
    <name>G4ML66_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_06703</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EHA56802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003709366.1"/>
    </dbReference>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_06703"/>
    <dbReference type="eggNOG" id="ENOG502S87A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090067_1_0_1"/>
    <dbReference type="InParanoid" id="G4ML66"/>
    <dbReference type="OMA" id="WASIFLH"/>
    <dbReference type="OrthoDB" id="432881at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140575">
        <property type="term" value="F:transmembrane monodehydroascorbate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08761">
        <property type="entry name" value="Cyt_b561_CYB561D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045150">
        <property type="entry name" value="CYB561D1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422:SF45">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15422">
        <property type="entry name" value="OS05G0565100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="31"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA56802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="243" mass="26677" checksum="2C3894AD834C1B05" modified="2011-12-14" version="1">MPDTMPTRRESEPLLGRPGDATQASNQPFYANLYLGTGFFTLVGVVMFCFEVWYSTLSQKFLPLFTPHPLLQSAAVAIALIGVLVLQPTTSADTERKRQGARLHVGIMGLAGLTFMAGVAIIEANKIKGNNPHFKSLHAYLGVATAIIIACQATFGVLMWAVPGAFGGVDNAKATWKYHRWFAYVVVLPMIVFTCLSSLGTGFNVNVLHMRPWIFYLSFILTIMGLAPRIHLDKLGFRQPTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLE8</accession>
    <name>G4MLE8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05429</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710290.1">
        <property type="nucleotide sequence ID" value="XM_003710242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLE8"/>
    <dbReference type="GeneID" id="2675957"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05429"/>
    <dbReference type="HOGENOM" id="CLU_1349177_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLE8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="203" mass="22349" checksum="D89EBE03686E8C8E" modified="2011-12-14" version="1">MQVNSITIQIQDVVGRRGPLVGQSSQCTWSGRVVFPLADRVYCSINSFDLITRANLIGRSWKNFKSHPGFPAIQYVCQPDLQARGLLFDSPAQCGELVFDSTVISMRYKSAGKQQIKRAVEESAHPKPPFVCNQRNREASRAVWVTLSNDGQLIARLAGTNASASVATTTDIAALWRDVKVQRGRDLGHGLGLNKGILIINQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2024-01-24" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN38</accession>
    <name>G4MN38_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710464.1">
        <property type="nucleotide sequence ID" value="XM_003710416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN38"/>
    <dbReference type="GeneID" id="12986346"/>
    <dbReference type="KEGG" id="mgr:MGG_16413"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16413"/>
    <dbReference type="InParanoid" id="G4MN38"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="123" mass="13354" checksum="21DBBFC8845E2A5F" modified="2011-12-14" version="1" fragment="single">TATPHGRPASTSSKAGRCTCFTKIPLQCTTQKAMTRDIGALRPERTVPVSFVGSCPWSCAGFEPVSPEGHGSWSDLSHMSQGHARVRQRKSHLCECEAGTKCMSTFVLILSEVVWDSQSEPKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNT4</accession>
    <name>G4MNT4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708912.1">
        <property type="nucleotide sequence ID" value="XM_003708864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNT4"/>
    <dbReference type="SMR" id="G4MNT4"/>
    <dbReference type="GeneID" id="12985706"/>
    <dbReference type="KEGG" id="mgr:MGG_16039"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16039"/>
    <dbReference type="eggNOG" id="ENOG502SYTK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122022_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNT4"/>
    <dbReference type="OMA" id="SHHDKEC"/>
    <dbReference type="OrthoDB" id="3555737at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="199" mass="21588" checksum="12C10DF166CB068B" modified="2011-12-14" version="1">MPSCSPCRAKGAASCQVSPQDSARCVECVRSNRSGCDVLGLSAAQIRHIGRQHSKLDAEVEALEEQIHVQQAKLLRLRKQKKLWFEKMMRAVSRGIDDLEELDRVERKEAEQEERRRSTEVLPEVSLESLLPDSNFVWDSTFPMGPLNPSLLDEMNVLAQHSVGSSGGMVSSPGRPLTSGNDPTPNSTGGAVPGNPGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP38</accession>
    <name>G4MP38_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="11">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_05700</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="11"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710599.1">
        <property type="nucleotide sequence ID" value="XM_003710551.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MP38"/>
    <dbReference type="STRING" id="242507.G4MP38"/>
    <dbReference type="GeneID" id="2676105"/>
    <dbReference type="KEGG" id="mgr:MGG_05700"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05700"/>
    <dbReference type="eggNOG" id="KOG0351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001103_16_1_1"/>
    <dbReference type="InParanoid" id="G4MP38"/>
    <dbReference type="OMA" id="MAINWTT"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18794">
        <property type="entry name" value="SF2_C_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001975">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000537">
        <property type="entry name" value="Bloom syndrome RecQ-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018982">
        <property type="entry name" value="RQC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF153">
        <property type="entry name" value="RECQ-LIKE DNA HELICASE BLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09382">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00956">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="881"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="1083"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="13">
        <location>
            <begin position="1510"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="20"/>
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    <feature type="region of interest" description="Disordered" evidence="12">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
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            <begin position="332"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="632"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="705"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="747"/>
            <end position="776"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="802"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1384"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1618"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="359"/>
            <end position="369"/>
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="804"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1384"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1405"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1435"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1637"/>
            <end position="1652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1663"/>
            <end position="1678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1711"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1744"/>
            <end position="1756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA57987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1780" mass="197635" checksum="525000920B9BE943" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-04-02" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQG0</accession>
    <name>G4MQG0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_16488</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710758.1">
        <property type="nucleotide sequence ID" value="XM_003710710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQG0"/>
    <dbReference type="GeneID" id="12986440"/>
    <dbReference type="KEGG" id="mgr:MGG_16488"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16488"/>
    <dbReference type="InParanoid" id="G4MQG0"/>
    <dbReference type="OrthoDB" id="4509994at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA58146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="183" mass="21060" checksum="FFF9FD95601F16D3" modified="2011-12-14" version="1" fragment="single">NVYSFIAEVNALADKIGVPAGERKITLWQHIPADLDHRLLRDSKDPRISYEEFANLVADAAHSIQRAYREREERKQKSRGKDRKEKYPYSPDKNRKSNRGRYYKSSNPNKGERSDMVPKTTEATGRGLTETEKMAHWEANTCFACGKEGHKSFECPNKTKAVRALDFEDNHSTNDEQKRSGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQK9</accession>
    <name>G4MQK9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14589</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709111.1">
        <property type="nucleotide sequence ID" value="XM_003709063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQK9"/>
    <dbReference type="STRING" id="242507.G4MQK9"/>
    <dbReference type="GeneID" id="5051393"/>
    <dbReference type="KEGG" id="mgr:MGG_14589"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14589"/>
    <dbReference type="HOGENOM" id="CLU_1475452_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQK9"/>
    <dbReference type="OMA" id="WYLANTF"/>
    <dbReference type="OrthoDB" id="5416609at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="183" mass="20432" checksum="DF632944BBC00B52" modified="2011-12-14" version="1">MVMAGLALMVVDDKKFRSRTMDFEVEQAINLHFFRKSKDKQFNTCIAHVFVVSIGTNTIGYQLKAENRTLIVARLRGGEPIARGDYQALPQAIYALAKTPDQSMVVFVEHIRGINPQAKVLLVAGVVQAGAMAVDKKESLRRKIESWGDVNNVALRVSENKYTGVKGTDTGDRLFNFTQWALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQY1</accession>
    <name>G4MQY1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709127.1">
        <property type="nucleotide sequence ID" value="XM_003709079.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709128.1">
        <property type="nucleotide sequence ID" value="XM_003709080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQY1"/>
    <dbReference type="GeneID" id="12984367"/>
    <dbReference type="KEGG" id="mgr:MGG_16105"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16105"/>
    <dbReference type="HOGENOM" id="CLU_2996917_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="57" mass="6329" checksum="936503D9D8549E88" modified="2011-12-14" version="1">MTEVGSVGEGETAELEKRRAEDLPFECSGCGKKWKTKSEADSCSAYHKTYPAWTARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQZ2</accession>
    <name>G4MQZ2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial phosphate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_02370</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709139.1">
        <property type="nucleotide sequence ID" value="XM_003709091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQZ2"/>
    <dbReference type="SMR" id="G4MQZ2"/>
    <dbReference type="FunCoup" id="G4MQZ2">
        <property type="interactions" value="651"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MQZ2"/>
    <dbReference type="GeneID" id="2681467"/>
    <dbReference type="KEGG" id="mgr:MGG_02370"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02370"/>
    <dbReference type="eggNOG" id="KOG0767">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039456_1_0_1"/>
    <dbReference type="InParanoid" id="G4MQZ2"/>
    <dbReference type="OMA" id="KMYIEEG"/>
    <dbReference type="OrthoDB" id="427452at2759"/>
    <dbReference type="PHI-base" id="PHI:2038"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000024">
        <property type="entry name" value="MIR1p Mitochondrial phosphate carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF12">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="17"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="115"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="213"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA56527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="309" mass="32502" checksum="D966E0B79A18946A" modified="2011-12-14" version="1">MAAIKKEAPVASPTGLSLYSKFALSGAVCCSVTHGMVTPLDVVKTRIQLDPQTYNRGMIGGFRQVIQNEGAGALLTGLGPTVAGYFLQGAFKFGGYEFFKAQSINTLGLETASKYRTSVYLASAAAAEFFADIALCPLEATRIRLVSDPSYANGLIGGFTKMLRTEGVGAFYAGFGPILFKQVPYTMTKFVVYEKVAEAIFRVYPKESLSDGMQTVVNLGSGLMAGFAAAIVSQPADTMLSKINKTKGLPGEGTTSRLIKIAKELGLRGSFGGIGARLFMVGTLTAGQFAIYGDLKKALGATGGVEIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR98</accession>
    <name>G4MR98_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_04708</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710835.1">
        <property type="nucleotide sequence ID" value="XM_003710787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR98"/>
    <dbReference type="STRING" id="242507.G4MR98"/>
    <dbReference type="GeneID" id="2677907"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04708"/>
    <dbReference type="eggNOG" id="ENOG502R28W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4MR98"/>
    <dbReference type="OMA" id="NMAPHFF"/>
    <dbReference type="OrthoDB" id="5600002at2759"/>
    <dbReference type="PHI-base" id="PHI:2044"/>
    <dbReference type="PHI-base" id="PHI:9182"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <source>
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    <sequence length="762" mass="80433" checksum="86AC7C6762D66971" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS38</accession>
    <name>G4MS38_PYRO7</name>
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        <submittedName>
            <fullName evidence="10">Glucose transporter HXT1</fullName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA57504.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSE5</accession>
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        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 17 protein</fullName>
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        <name evidence="2" type="ORF">MGG_04516</name>
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            <taxon>Sordariomycetes</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713564.1">
        <property type="nucleotide sequence ID" value="XM_003713516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSE5"/>
    <dbReference type="CAZy" id="GT17">
        <property type="family name" value="Glycosyltransferase Family 17"/>
    </dbReference>
    <dbReference type="GeneID" id="2678034"/>
    <dbReference type="KEGG" id="mgr:MGG_04516"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04516"/>
    <dbReference type="eggNOG" id="ENOG502QPVW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038606_1_0_1"/>
    <dbReference type="InParanoid" id="G4MSE5"/>
    <dbReference type="OMA" id="FEWPAGE"/>
    <dbReference type="OrthoDB" id="6474464at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="InterPro" id="IPR006813">
        <property type="entry name" value="Glyco_trans_17"/>
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        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
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    </dbReference>
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        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE"/>
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    </dbReference>
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        <property type="entry name" value="Glyco_transf_17"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466085" evidence="1">
        <location>
            <begin position="28"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="369" mass="42586" checksum="FE62EA9128E6224D" modified="2011-12-14" version="1">MAPIRKLRIWVVVPLAMLLVFLWHRQADVASDATSSSPPSAAHRVSVDMFHQVPGLPDAAMCRMHGWRPYQTPASGRKRKVYDLFMINTELEWLEIRLNTSYHEVDHFIVVEAPLTFTGLPKPLIIKENWERFAPYHDKLIYHELQYPPGYDPPRAWDREDLQRDAMLTQVFPGLEGGVSQPQDGDVIIVADVDEVVRPETLRLLRACAFPRRLTLRSRFYYYSFEFLHRGPEWAHPQATTYAGSVDATIKPTNLRNGDGGLGPLIYFDKDDLWNAGWHCSSCYATMSEVLTKMASFSHVSLNQDFFRDRNRIADRVREGLDLWSRADQIYDRIKDNKDLPPFVLNHKDRFVHLLDRSGKSAGFSDYPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSQ4</accession>
    <name>G4MSQ4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polyphosphoinositide phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_07091</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715282.1">
        <property type="nucleotide sequence ID" value="XM_003715234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSQ4"/>
    <dbReference type="SMR" id="G4MSQ4"/>
    <dbReference type="FunCoup" id="G4MSQ4">
        <property type="interactions" value="762"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSQ4"/>
    <dbReference type="GeneID" id="2682976"/>
    <dbReference type="KEGG" id="mgr:MGG_07091"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07091"/>
    <dbReference type="eggNOG" id="KOG1888">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003016_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSQ4"/>
    <dbReference type="OMA" id="NYINWYT"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043813">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043573">
        <property type="entry name" value="Fig4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738:SF5">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="5">
        <location>
            <begin position="289"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="821"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="925"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="822"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="934"/>
            <end position="946"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1104" mass="124501" checksum="21F406CBE60C518E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSQ7</accession>
    <name>G4MSQ7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mob1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715285.1">
        <property type="nucleotide sequence ID" value="XM_003715237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSQ7"/>
    <dbReference type="SMR" id="G4MSQ7"/>
    <dbReference type="STRING" id="242507.G4MSQ7"/>
    <dbReference type="GeneID" id="2682980"/>
    <dbReference type="KEGG" id="mgr:MGG_07095"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07095"/>
    <dbReference type="eggNOG" id="KOG1852">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027210_1_0_1"/>
    <dbReference type="InParanoid" id="G4MSQ7"/>
    <dbReference type="OMA" id="YCCAIDY"/>
    <dbReference type="OrthoDB" id="10262609at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="390"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="569"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="61795" checksum="3A717AE6C82705F4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MST0</accession>
    <name>G4MST0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM2-LSM8 complex subunit LSM8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM8</name>
        <name evidence="11" type="ORF">MGG_04539</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA53784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003713543.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MST0"/>
    <dbReference type="SMR" id="G4MST0"/>
    <dbReference type="FunCoup" id="G4MST0">
        <property type="interactions" value="398"/>
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    <dbReference type="STRING" id="242507.G4MST0"/>
    <dbReference type="GeneID" id="2678209"/>
    <dbReference type="KEGG" id="mgr:MGG_04539"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04539"/>
    <dbReference type="eggNOG" id="KOG1784">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076902_8_1_1"/>
    <dbReference type="InParanoid" id="G4MST0"/>
    <dbReference type="OMA" id="AACDQTT"/>
    <dbReference type="OrthoDB" id="422364at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA53784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="101" mass="11083" checksum="E668857C0941C325" modified="2011-12-14" version="1">MVHLLNSYVDKRVVIMTTDGRMLIGTLINSDNQANIILYNVTERHIAPADGDEDSVDRPSVGTEIIRGSTILVVGLVDEELEGSIDWTKVRGEPIGDTYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSX5</accession>
    <name>G4MSX5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714441.1">
        <property type="nucleotide sequence ID" value="XM_003714393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSX5"/>
    <dbReference type="GeneID" id="2679673"/>
    <dbReference type="KEGG" id="mgr:MGG_01479"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01479"/>
    <dbReference type="eggNOG" id="ENOG502T5QF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_888707_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSX5"/>
    <dbReference type="OMA" id="HAWTICS"/>
    <dbReference type="OrthoDB" id="4763068at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051285">
        <property type="term" value="C:cell cortex of cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052413">
        <property type="entry name" value="SUR7_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019">
        <property type="entry name" value="CELL MEMBRANE PROTEIN YLR413W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28019:SF7">
        <property type="entry name" value="SUR7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="313" mass="33345" checksum="31C027CA8606966F" modified="2011-12-14" version="1">MSLVHNKTTIDSTEQYPKMHALLGFLFPILLALAAFVLSLLASLAGVKAGFMPDSNIALLDTSRMGLDAVLVGNNAPSIVRRSLGMGSGKTNNENNKLINGTKDEVAKAIKDAVGLDQFYAVHAWTICSGTFVNKNDPSGGLDVRVCWPLYQINLTDLLEMDLKLSGPVRGAIREVGAAAPRIPRVIGDLFTTAYLLCIFSVLPSVIAAHFTLPRGPGGGYHRPPFWTHVLNLAAAGLAFVMLVAASAVATAGANRIARAVRDEAVWLGMRVEAGARFQGMAWTATALMGVASLYHVLAGFLTSRNRSSKSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT16</accession>
    <name>G4MT16_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714482.1">
        <property type="nucleotide sequence ID" value="XM_003714434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT16"/>
    <dbReference type="GeneID" id="12984677"/>
    <dbReference type="KEGG" id="mgr:MGG_15722"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15722"/>
    <dbReference type="HOGENOM" id="CLU_2758273_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT16"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="70" mass="7747" checksum="C98E0B12E666FDCD" modified="2011-12-14" version="1">MSSSKLNMRNTVPGKSNHKPAVYRRLVCIGRIGSGPFPWRAPIILIRQYALIPGDTEHAKRAKAQHPSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTB4</accession>
    <name>G4MTB4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713667.1">
        <property type="nucleotide sequence ID" value="XM_003713619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTB4"/>
    <dbReference type="STRING" id="242507.G4MTB4"/>
    <dbReference type="GeneID" id="2678102"/>
    <dbReference type="KEGG" id="mgr:MGG_04672"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04672"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028281_6_1_1"/>
    <dbReference type="InParanoid" id="G4MTB4"/>
    <dbReference type="OMA" id="QHEFPGK"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465379" description="SET domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="135"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="447" mass="50169" checksum="E00795CC0112AAD0" modified="2011-12-14" version="1">MKAVQVLSFYFVAVLAARDSIQNHLALGICRSPLLPLSFPELTDPICSTADVIAQRQAAGGRHITDESSPWTSISNCARNGTGPTEFCVFYAGGFANNRGVSIITSPARAKSIAKLPAFTNPELTAHTNKDLDPNYTAVYKSVMVPGKGVGLVAARTLYRGDRIMSSTPAIVIDYGFFETMPKKIVREIQTAAVDILPENHRQLLLNLSSHDGLYENYQQKVDKILSTNAFDIDADPEGDNDDQFYVVFPEISRCNHDCRPNADYYYDPETLTQHVHAVRQINIGEEISLSYLDPLQSQAARLARLSRTWGFPCGCSMCTQRDLIAEESDSRLEQIAELRKEFHDYTPSSRATPQMAELMVSLYQQERLDLMLYEAFTYAAIEYNGVGEPWMATKYARLAVEYGLASVGPKDNDVIEMDNLVLDPFKHWSWMLRTSKRMSWGKKRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTC6</accession>
    <name>G4MTC6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA53872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713679.1">
        <property type="nucleotide sequence ID" value="XM_003713631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTC6"/>
    <dbReference type="GeneID" id="12987174"/>
    <dbReference type="KEGG" id="mgr:MGG_15558"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15558"/>
    <dbReference type="HOGENOM" id="CLU_2942221_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTC6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="60" mass="6705" checksum="BFA58738D42BC345" modified="2011-12-14" version="1">MEALIKPPHSYLRYCKLQGSLPRKAPSLKKSVRNPASSNINVSHTSDLRSDTLSDVRLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU17</accession>
    <name>G4MU17_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcofluor white hypersensitive protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_07212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715424.1">
        <property type="nucleotide sequence ID" value="XM_003715376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU17"/>
    <dbReference type="SMR" id="G4MU17"/>
    <dbReference type="GeneID" id="2683100"/>
    <dbReference type="KEGG" id="mgr:MGG_07212"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07212"/>
    <dbReference type="eggNOG" id="ENOG502SSX2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129945_1_0_1"/>
    <dbReference type="InParanoid" id="G4MU17"/>
    <dbReference type="OMA" id="KHQMRID"/>
    <dbReference type="OrthoDB" id="5355126at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="13650" checksum="96CD1EEC378E427C" modified="2011-12-14" version="1">MSKSRVPMMLGVAGVSGVGYYLYQAGGSPKVAEKEFEKDIHSASAKLKSELPGRGSEAQKEAEKLGAQAGAKFDSAISNAKSEAAKLKAESEAYAKEAKAGAMKKVDEFDKKVEDGAAKAKSGVSSWFGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUE2</accession>
    <name>G4MUE2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transmembrane 14C domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_01651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714636.1">
        <property type="nucleotide sequence ID" value="XM_003714588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUE2"/>
    <dbReference type="GeneID" id="2679292"/>
    <dbReference type="KEGG" id="mgr:MGG_01651"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01651"/>
    <dbReference type="HOGENOM" id="CLU_2210549_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUE2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="107" mass="11880" checksum="D7B53792A9855B10" modified="2011-12-14" version="1">MLGRIPVRPRWLQDSEPPVLRRRAVPCCLGHPRRRFHPPRHSPAEACAHCSQLALNVWCAHIRECRSSGCVDDVRIPTRDGTAKALLGEEDLAGRGDAKGFSLHNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUN8</accession>
    <name>G4MUN8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_10189</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays an important role in cellulose degradation. Shows hydrolytic activity against several glycosidic compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3"/>
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        <property type="protein sequence ID" value="EHA54011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003713770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUN8"/>
    <dbReference type="SMR" id="G4MUN8"/>
    <dbReference type="STRING" id="242507.G4MUN8"/>
    <dbReference type="GeneID" id="2681761"/>
    <dbReference type="KEGG" id="mgr:MGG_10189"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10189"/>
    <dbReference type="eggNOG" id="KOG0626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001859_1_2_1"/>
    <dbReference type="InParanoid" id="G4MUN8"/>
    <dbReference type="OMA" id="HGSNDFY"/>
    <dbReference type="OrthoDB" id="65569at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080079">
        <property type="term" value="F:cellobiose glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000011">
        <property type="entry name" value="Cytosolic beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GLHYDRLASE1"/>
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        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00056775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA54011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="512" mass="57950" checksum="8D72C838D63A0251" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV95</accession>
    <name>G4MV95_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_01727</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA54917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003714676.1"/>
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    </dbReference>
    <dbReference type="STRING" id="242507.G4MV95"/>
    <dbReference type="GeneID" id="2679747"/>
    <dbReference type="KEGG" id="mgr:MGG_01727"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01727"/>
    <dbReference type="eggNOG" id="KOG4372">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007367_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV95"/>
    <dbReference type="OMA" id="WSYIRPT"/>
    <dbReference type="OrthoDB" id="5368485at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF62">
        <property type="entry name" value="LIPASE ROG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="399"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="570"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="344"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="433"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="761"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="870"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="964"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1110"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="348"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="433"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="761"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="894"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="976"/>
            <end position="990"/>
        </location>
    </feature>
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            <end position="1019"/>
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    </feature>
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        <location>
            <begin position="1020"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1110"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1142"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1189"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1224"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1241"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1334"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1354"/>
            <end position="1363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA54917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1373" mass="149127" checksum="157653821C0518FC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW17</accession>
    <name>G4MW17_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATPase AAA-type core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_08943</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CbxX/CfxQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713977.1">
        <property type="nucleotide sequence ID" value="XM_003713929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW17"/>
    <dbReference type="STRING" id="242507.G4MW17"/>
    <dbReference type="GeneID" id="2679929"/>
    <dbReference type="KEGG" id="mgr:MGG_08943"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08943"/>
    <dbReference type="eggNOG" id="KOG1807">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_609840_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW17"/>
    <dbReference type="OMA" id="RTDEFRR"/>
    <dbReference type="OrthoDB" id="2423195at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000641">
        <property type="entry name" value="CbxX/CfxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050773">
        <property type="entry name" value="CbxX/CfxQ_RuBisCO_ESX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN / ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43392:SF2">
        <property type="entry name" value="AAA-TYPE ATPASE FAMILY PROTEIN _ ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00819">
        <property type="entry name" value="CBXCFQXSUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="5">
        <location>
            <begin position="281"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="33"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA54170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="449" mass="50201" checksum="D2C06A2312A50CF4" modified="2011-12-14" version="1">MAAGKPPATTSLRRPPRRLGYKKLSFIESAWPVGSRPQLRRAPRGSQSSSAPDAPGPVPVSPNVHISKPPGWIQDHRAPSDQRALETALVKHLALQGYGTDNMVALIPYLDCCIYCMTRFVGIAERRTDEFRRVQGRRHLHRFLDPQQLPRGHWLHGRSGALQCPDLSNENSRRLSTPSTRCFWEVRDRERPRLPSCMSAILVDLGILTKGRVVVKNPSDFVGAALGRSEERRKGILATTAGKVLVVDEAFELYGGSAQGPLQYRRQRHHRGRESIPLNTLFGGPPETGKTTTAKKAGKVFYDMAFVLTADVIKYSATDLVGQYVGQTGAKVLQLLNKALGWVLLIDEVYGLGEGHFANSRRKSKTNRQAPTPLQQLTLTTSMRRLYYTRSRTRAGGRVPVAEKEAEEARDVDRNAIVNQLLQGEDRQKKDLSVEAKLERWKDADWIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWF8</accession>
    <name>G4MWF8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_08974</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714013.1">
        <property type="nucleotide sequence ID" value="XM_003713965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWF8"/>
    <dbReference type="STRING" id="242507.G4MWF8"/>
    <dbReference type="GeneID" id="2679959"/>
    <dbReference type="KEGG" id="mgr:MGG_08974"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08974"/>
    <dbReference type="eggNOG" id="ENOG502RX7Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019313_1_0_1"/>
    <dbReference type="InParanoid" id="G4MWF8"/>
    <dbReference type="OMA" id="ALAWPMC"/>
    <dbReference type="OrthoDB" id="5213892at2759"/>
    <dbReference type="PHI-base" id="PHI:5685"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF20">
        <property type="entry name" value="PRO1A C6 ZINK-FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="534"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA54206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="704" mass="75484" checksum="134AADC9B894CE33" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX31</accession>
    <name>G4MX31_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003714888.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="12985464"/>
    <dbReference type="KEGG" id="mgr:MGG_15797"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15797"/>
    <dbReference type="HOGENOM" id="CLU_2413678_0_0_1"/>
    <dbReference type="InParanoid" id="G4MX31"/>
    <dbReference type="OrthoDB" id="5168519at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="92" mass="10150" checksum="9086A4808C67EC24" modified="2011-12-14" version="1">MASVKDDVLIITFGTSGIKPLLFDKWMEGVALLISARDWRATGFESTRVSRGMGIWDRMTLWIAFRPGGLKANGELITVICEMVSGIGSDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
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    <name>G4MXI8_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">DUF7624 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11261</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714126.1">
        <property type="nucleotide sequence ID" value="XM_003714078.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MXI8"/>
    <dbReference type="STRING" id="242507.G4MXI8"/>
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    <dbReference type="KEGG" id="mgr:MGG_11261"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11261"/>
    <dbReference type="eggNOG" id="ENOG502SKIF">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014596_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXI8"/>
    <dbReference type="OMA" id="REGWTQV"/>
    <dbReference type="OrthoDB" id="5230484at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056041">
        <property type="entry name" value="DUF7624"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24616">
        <property type="entry name" value="DUF7624"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="616"/>
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        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="617" mass="67853" checksum="26D54056DC8A0D1E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY58</accession>
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    <protein>
        <submittedName>
            <fullName evidence="3">G patch domain-containing protein 1</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_11240</name>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714196.1">
        <property type="nucleotide sequence ID" value="XM_003714148.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MY58"/>
    <dbReference type="STRING" id="242507.G4MY58"/>
    <dbReference type="GeneID" id="5051208"/>
    <dbReference type="KEGG" id="mgr:MGG_11240"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11240"/>
    <dbReference type="eggNOG" id="KOG2138">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_008613_3_0_1"/>
    <dbReference type="InParanoid" id="G4MY58"/>
    <dbReference type="OMA" id="MIQFVRK"/>
    <dbReference type="OrthoDB" id="20507at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011666">
        <property type="entry name" value="DUF1604"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
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    <dbReference type="PANTHER" id="PTHR13384">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13384:SF19">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 1"/>
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        <property type="entry name" value="DUF1604"/>
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        <property type="entry name" value="G-patch"/>
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        <property type="entry name" value="HTH_TGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
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        <location>
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            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        <location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="568"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYB1</accession>
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        <submittedName>
            <fullName evidence="8">AP-3 adaptor complex subunit mu</fullName>
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    <organism evidence="8 9">
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
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    <comment type="similarity">
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA55246.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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</entry>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003714228.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_11224"/>
    <dbReference type="eggNOG" id="ENOG502S2E4">
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    <dbReference type="Proteomes" id="UP000009058">
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        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
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    </dbReference>
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        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
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    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
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        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465514" description="RlpA-like protein double-psi beta-barrel domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="102"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="191"/>
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        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="31075" checksum="D0D823889C986711" modified="2011-12-14" version="1">MRSTTILSVAALASTALAQPFAFGHNHHARHHHARRGAAAVGKRDIVTEWTTEWVTETATEYIDMTSTVVINTATTPGQFFEGSSTPPAVPATKPTPSSQAAPPPPPPPPSPTPPSPTPQTPSPSTPPVQQSPTPAPAAPKVQQAPEPAAPKVQQAPQPAPQVQQAPEPARAPAPLSIPSPPAPVAPSPPSSDSSSGAMSFTGQVTHYTVGLGACGFDDAGKDNSEYIVAISSALMHGSNGDPMCNKKVNLSFEGHSITATIRDKCPSCSKEQIDLSEKAFLDLVGPLGIGRQGGVKWTIA</sequence>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYU1</accession>
    <name>G4MYU1_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08158</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Sordariomycetes</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715127.1">
        <property type="nucleotide sequence ID" value="XM_003715079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYU1"/>
    <dbReference type="STRING" id="242507.G4MYU1"/>
    <dbReference type="GeneID" id="2678362"/>
    <dbReference type="KEGG" id="mgr:MGG_08158"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08158"/>
    <dbReference type="eggNOG" id="ENOG502SSJ3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051203_1_0_1"/>
    <dbReference type="InParanoid" id="G4MYU1"/>
    <dbReference type="OMA" id="TMYVRRG"/>
    <dbReference type="OrthoDB" id="3941683at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="234" mass="23343" checksum="F85039F774060FD2" modified="2011-12-14" version="1">MVNYRFATLIGLAGMAVAVPLNINLGAYSPALVVGDGEISFKGGEEGGKKAGAAAIASAPGAAAAAAAPVSNAASQQQPAQIVSAPATADAASAPNPALEQQAQQIAALQGMGKAIAPRQEGEAAEEDTEPEEKTSAVTKRDTESAEVEAESEEDDEAPAVAKRDLASFQAALAFAEKALTKGPIISLGTGEGSQKAGVGIVVNNNPAGGAAKGKERKKRDLGVSQKVKVTTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZA8</accession>
    <name>G4MZA8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP-binding protein EsdC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715188.1">
        <property type="nucleotide sequence ID" value="XM_003715140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZA8"/>
    <dbReference type="SMR" id="G4MZA8"/>
    <dbReference type="STRING" id="242507.G4MZA8"/>
    <dbReference type="GeneID" id="5050917"/>
    <dbReference type="KEGG" id="mgr:MGG_12316"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12316"/>
    <dbReference type="eggNOG" id="ENOG502QVY6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063252_1_0_1"/>
    <dbReference type="InParanoid" id="G4MZA8"/>
    <dbReference type="OMA" id="WDNYAGQ"/>
    <dbReference type="OrthoDB" id="5364946at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40625:SF2">
        <property type="entry name" value="GTP-BINDING PROTEIN ESDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40625">
        <property type="entry name" value="GTP-BINDING PROTEIN ESDC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="31923" checksum="41D29A51EBF3B746" modified="2011-12-14" version="1">MSTQLSFSLRVSSGVKSVHLLGSWDNYQGQLPLSKDKTSSKSGSWKGTFRFPGSTLESGQRYWYYYIIDGYHCAHNPSEASTVEPTTGRSLNILDVAKSSSSSKSSSKSSSSSKSSSRHSSSSKSSSKSSSSSSSKRSSDVAKGRPLSVSQIKAPKPMAPHATRHILDGSYDDEEVAELAERFGYATFEDEYNEDLVTDFGSSSPVSSVGSGSDLSSYYRSDSSSPNSSMSGYSTPSSDCSSCTCERYGITRKGDRVRLDCGGSRCGYDNESECSSGSEDEYVSSRSSRRNGMVVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZC6</accession>
    <name>G4MZC6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_04374</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713488.1">
        <property type="nucleotide sequence ID" value="XM_003713440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZC6"/>
    <dbReference type="SMR" id="G4MZC6"/>
    <dbReference type="STRING" id="242507.G4MZC6"/>
    <dbReference type="GeneID" id="2677881"/>
    <dbReference type="KEGG" id="mgr:MGG_04374"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04374"/>
    <dbReference type="eggNOG" id="ENOG502SA5X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048021_1_0_1"/>
    <dbReference type="InParanoid" id="G4MZC6"/>
    <dbReference type="OMA" id="WVKSHTP"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465558" description="HMG box domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="239"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="239"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA53681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="309" mass="34181" checksum="6066A3E42E3AC706" modified="2011-12-14" version="1">MWIRPATMMLATAMRAGALTSGSRVANVAAYRLVLAARPMATAAANKSTATTTGAAAAAGKAKAAPKKKAAAKPKAKNTQAKPKAVKKKAVKVSRPPQSPERIEAQKLAAKKKAMREKRIELTRLGLFTEPPKEPEVALRVFLKQWCAKNSIPGKGPVFQDMHNAFKALSPAELQELEETAAKNKISNEIAHKAWVQSHTPSEINEANKARHYLARVFKLKSVKGVCLTRGHIKDDRIPSSPLSPYMNFMKLRLKELSHQAPDNFRTGVNMTDAATAWKKLSEAERKVYEDMFRAERADYDRKKMELNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZG8</accession>
    <name>G4MZG8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ent-kaurene oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_01391</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714334.1">
        <property type="nucleotide sequence ID" value="XM_003714286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZG8"/>
    <dbReference type="SMR" id="G4MZG8"/>
    <dbReference type="STRING" id="242507.G4MZG8"/>
    <dbReference type="GeneID" id="2679133"/>
    <dbReference type="KEGG" id="mgr:MGG_01391"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01391"/>
    <dbReference type="eggNOG" id="KOG0684">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022195_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZG8"/>
    <dbReference type="OMA" id="CRSEQYL"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="522" mass="58161" checksum="095276968A36CDCA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZR9</accession>
    <name>G4MZR9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_07059</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715240.1">
        <property type="nucleotide sequence ID" value="XM_003715192.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MZR9"/>
    <dbReference type="FunCoup" id="G4MZR9">
        <property type="interactions" value="936"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZR9"/>
    <dbReference type="GeneID" id="2682944"/>
    <dbReference type="KEGG" id="mgr:MGG_07059"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07059"/>
    <dbReference type="eggNOG" id="KOG0920">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_4_0_1"/>
    <dbReference type="InParanoid" id="G4MZR9"/>
    <dbReference type="OMA" id="LFRVCNM"/>
    <dbReference type="OrthoDB" id="5600252at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23827">
        <property type="entry name" value="RWD_YLR419W-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000868">
        <property type="entry name" value="DEAD/DEAH box helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
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    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056328">
        <property type="entry name" value="DSRM_DHX29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059023">
        <property type="entry name" value="RNA_hel_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF267">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE YLR419W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24385">
        <property type="entry name" value="DSRM_DHX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26026">
        <property type="entry name" value="RNA_hel_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="643"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="869"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA55433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1404" mass="154152" checksum="0F5205A079BA8D34" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0N4</accession>
    <name>G4N0N4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712972.1">
        <property type="nucleotide sequence ID" value="XM_003712924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0N4"/>
    <dbReference type="GeneID" id="12985879"/>
    <dbReference type="KEGG" id="mgr:MGG_16922"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16922"/>
    <dbReference type="HOGENOM" id="CLU_2171566_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0N4"/>
    <dbReference type="OrthoDB" id="10512811at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="110" mass="11809" checksum="5D6815B11A981981" modified="2011-12-14" version="1">MVSWERALEETSDISAAETASRSTRAIHLPLQDLDGTAINDLLEVVDARPHQPAALSDGRPGTAPTPATRSHWSARFLVGGSPATNRQVQTLMSLCCRVAAQGLFGLKTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N150</accession>
    <name>G4N150_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anaphase-promoting complex subunit cut9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711336.1">
        <property type="nucleotide sequence ID" value="XM_003711288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N150"/>
    <dbReference type="SMR" id="G4N150"/>
    <dbReference type="FunCoup" id="G4N150">
        <property type="interactions" value="1143"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N150"/>
    <dbReference type="GeneID" id="2683360"/>
    <dbReference type="KEGG" id="mgr:MGG_07440"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07440"/>
    <dbReference type="eggNOG" id="KOG1173">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011751_4_1_1"/>
    <dbReference type="InParanoid" id="G4N150"/>
    <dbReference type="OMA" id="DPFHNNA"/>
    <dbReference type="OrthoDB" id="10006270at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005721">
        <property type="term" value="C:pericentric heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="455"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="95"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="617"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="622"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="636"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA51529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="664" mass="73449" checksum="F30AA84FDB3056AE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-10-16" modified="2025-02-05" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2X2</accession>
    <name>ABA2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome P450 monooxygenase ABA2</fullName>
            <ecNumber evidence="8">1.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Abscisic acid biosynthesis protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ABA2</name>
        <name type="ORF">MGG_07982</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2015" name="Front. Plant Sci." volume="6" first="1082" last="1082">
            <title>Crucial roles of abscisic acid biogenesis in virulence of rice blast fungus Magnaporthe oryzae.</title>
            <authorList>
                <person name="Spence C.A."/>
                <person name="Lakshmanan V."/>
                <person name="Donofrio N."/>
                <person name="Bais H.P."/>
            </authorList>
            <dbReference type="PubMed" id="26648962"/>
            <dbReference type="DOI" id="10.3389/fpls.2015.01082"/>
        </citation>
        <scope>IDENTIFICATION</scope>
        <scope>INDUCTION</scope>
        <scope>FUNCTION</scope>
        <scope>PATHWAY</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2017" name="Front. Plant Sci." volume="8" first="587" last="587">
            <title>Abscisic acid as pathogen effector and immune regulator.</title>
            <authorList>
                <person name="Lievens L."/>
                <person name="Pollier J."/>
                <person name="Goossens A."/>
                <person name="Beyaert R."/>
                <person name="Staal J."/>
            </authorList>
            <dbReference type="PubMed" id="28469630"/>
            <dbReference type="DOI" id="10.3389/fpls.2017.00587"/>
        </citation>
        <scope>FUNCTION</scope>
    </reference>
    <comment type="function">
        <text evidence="2 5">Cytochrome P450 monooxygenase involved in the biosynthesis of abscisic acid (ABA), a phytohormone that acts antagonistically toward salicylic acid (SA), jasmonic acid (JA) and ethylene (ETH) signaling, to impede plant defense responses (PubMed:26648962). During pathogen-host interaction, ABA plays a dual role in disease severity by increasing plant susceptibility and accelerating pathogenesis in the fungus itself (PubMed:26648962). The first step of the pathway catalyzes the reaction from farnesyl diphosphate to alpha-ionylideneethane performed by the alpha-ionylideneethane synthase ABA3 via a three-step reaction mechanism involving 2 neutral intermediates, beta-farnesene and allofarnesene (By similarity). The cytochrome P450 monooxygenase ABA1 might then be involved in the conversion of alpha-ionylideneethane to alpha-ionylideneacetic acid (By similarity). Alpha-ionylideneacetic acid is further converted to abscisic acid in 2 steps involving the cytochrome P450 monooxygenase ABA2 and the short-chain dehydrogenase/reductase ABA4, via the intermediates 1'-deoxy-ABA or 1',4'-trans-diol-ABA, depending on the order of action of these 2 enzymes (By similarity). ABA2 is responsible for the hydroxylation of carbon atom C-1' and ABA4 might be involved in the oxidation of the C-4' carbon atom.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Hormone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="5">Expression is induced in spores.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713228.1">
        <property type="nucleotide sequence ID" value="XM_003713180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2X2"/>
    <dbReference type="SMR" id="G4N2X2"/>
    <dbReference type="STRING" id="242507.G4N2X2"/>
    <dbReference type="GlyCosmos" id="G4N2X2">
        <property type="glycosylation" value="1 site, No reported glycans"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_07982T0">
        <property type="protein sequence ID" value="MGG_07982T0"/>
        <property type="gene ID" value="MGG_07982"/>
    </dbReference>
    <dbReference type="GeneID" id="2683909"/>
    <dbReference type="KEGG" id="mgr:MGG_07982"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07982"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="InParanoid" id="G4N2X2"/>
    <dbReference type="OMA" id="SSWCAHH"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009688">
        <property type="term" value="P:abscisic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="GO_Central"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0349">Heme</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0503">Monooxygenase</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <feature type="chain" id="PRO_0000448417" description="Cytochrome P450 monooxygenase ABA2">
        <location>
            <begin position="1"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="4">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="P04798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="Q5K0D9"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3"/>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="26648962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="6">
        <source>
            <dbReference type="PubMed" id="26648962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="7"/>
    <evidence type="ECO:0000305" key="8">
        <source>
            <dbReference type="PubMed" id="26648962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA53421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="521" mass="58440" checksum="A11E5D80B3E4779D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2Z8</accession>
    <name>G4N2Z8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711564.1">
        <property type="nucleotide sequence ID" value="XM_003711516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2Z8"/>
    <dbReference type="GeneID" id="12984135"/>
    <dbReference type="KEGG" id="mgr:MGG_16668"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16668"/>
    <dbReference type="HOGENOM" id="CLU_2210553_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2Z8"/>
    <dbReference type="OrthoDB" id="5217705at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="107" mass="11303" checksum="8DBF5C866D55591F" modified="2011-12-14" version="1">MFKQALRKPLTGAVVQQQRVRSLHRDAPYLFSMPAEVDAARKASVATPTASTIPSTSFSAGSSASSATAQQSAQRRGFSLYQDAPYLCSLPEEVKAIKTDGASAAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3Q9</accession>
    <name>G4N3Q9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711690.1">
        <property type="nucleotide sequence ID" value="XM_003711642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3Q9"/>
    <dbReference type="STRING" id="242507.G4N3Q9"/>
    <dbReference type="GeneID" id="2684114"/>
    <dbReference type="KEGG" id="mgr:MGG_05861"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05861"/>
    <dbReference type="HOGENOM" id="CLU_674505_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3Q9"/>
    <dbReference type="OMA" id="VELINPC"/>
    <dbReference type="OrthoDB" id="410198at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="133"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="408" mass="45009" checksum="9C814CA6E5A1FFCF" modified="2011-12-14" version="1">MPSRTDLCCRNEARAGKIKMTVVRRNLLHSPSTSPEIKFTPPHKTATGLVQNGRDHGGKDTDETPGKDAPPLASDMAAPRDDGILRTWHYSHLKYDPTPPSNHCGTIRRADHTLHLDGIVDLVVAATPDIPVMTFRNPHLGKSAAHAAAYRANTRKRYLSDLLQRYVESGHVLVFVLPGGNQVVGLAVWSYHNASVDGELGSGDITVTREELAELKAEVKRQKRNGGGAENGDHDAGDAFRDAAFRIYNLRCQDSLAKGGNEPMMLWLRMLCVHPEHRGKGIGAAMVEEGIRLQRGDGVTKWAALYSSSEAAAKLYRRLGFRDHGGFEIKLGELDNVDGEEKLNVRVMARKIRQGSEVELRDVELINPCKVHIPTAAQLEKWGVTDWNNLVVEGLPWDGVVSQIALRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3U4</accession>
    <name>G4N3U4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_16840</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712524.1">
        <property type="nucleotide sequence ID" value="XM_003712476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3U4"/>
    <dbReference type="SMR" id="G4N3U4"/>
    <dbReference type="GeneID" id="12985067"/>
    <dbReference type="KEGG" id="mgr:MGG_16840"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16840"/>
    <dbReference type="eggNOG" id="ENOG502S5K7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050230_0_2_1"/>
    <dbReference type="InParanoid" id="G4N3U4"/>
    <dbReference type="OMA" id="CPAMNSL"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="PHI-base" id="PHI:5188"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF19">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465956" description="Heme haloperoxidase family profile domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="29"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="242" mass="25990" checksum="36E5E3F9607487E7" modified="2011-12-14" version="1">MVSTRTLTALLCTVVPLTWAYPSMIEARDDHPFMAPSPNDRRSPCPMMNTLANHGFIPRTNISMDQLVSALELSIGLEGAATRIVGGKALATSTTGNPNTFNLDDLVKHGILEHDGSLSRSDLADGDNHSFNKTLWDTTLTFFKDDKISIAQGAAARNAAIAAAKARNPKFAMAAGDAQNSAVESALYLRVFGGVNGDARKDWVKILFEQERMPYAEGFPQKPAGKITAQEILGIVSKLTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3X1</accession>
    <name>G4N3X1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MalT-like TPR region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712551.1">
        <property type="nucleotide sequence ID" value="XM_003712503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3X1"/>
    <dbReference type="SMR" id="G4N3X1"/>
    <dbReference type="STRING" id="242507.G4N3X1"/>
    <dbReference type="GeneID" id="12985094"/>
    <dbReference type="KEGG" id="mgr:MGG_16849"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16849"/>
    <dbReference type="eggNOG" id="KOG4658">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_906385_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3X1"/>
    <dbReference type="OMA" id="ECIRISS"/>
    <dbReference type="OrthoDB" id="5231595at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="30440" checksum="AC8B71B34E2F9D5D" modified="2011-12-14" version="1">MTTLTYASAIDLGGLLDLDLAQAPRALGPFKRALEIRRARLGPEDPFIAYSLNNIALAYTEMGELELAHEAHAEAVRLRREANSDRIGNSYSNLSSLLLRMGRPDEAEEMLARCPSLKDFTDETFLATGNPRFSGDMVLLSRIRLAQGRTTEAIRLASKALEFRRELLGNRLKTCDSQYDVARMLALEGFESSAIQLLEEIVSISETFVEGQGQRARALYKLSGIYHKGGKKASSDECKQRALELRADMRPERSDAPFEEAEFGKLCSWMLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3Z8</accession>
    <name>G4N3Z8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711727.1">
        <property type="nucleotide sequence ID" value="XM_003711679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3Z8"/>
    <dbReference type="STRING" id="242507.G4N3Z8"/>
    <dbReference type="GeneID" id="2684074"/>
    <dbReference type="KEGG" id="mgr:MGG_05901"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05901"/>
    <dbReference type="eggNOG" id="ENOG502RA2J">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070836_1_0_1"/>
    <dbReference type="InParanoid" id="G4N3Z8"/>
    <dbReference type="OMA" id="FTIYATI"/>
    <dbReference type="OrthoDB" id="58379at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="327" mass="36399" checksum="6E0374031EDAF956" modified="2011-12-14" version="1">MADEKKSRHSWNPFSSHGRTSPQPPRPLSQGEPSSQGSAAPASSSSDPTKGPWQPEQHLQPPPSFQESQAYAAPPPPPTAAAAGSSSAAPVFRSQFACVTLNMFDRIRLINFPPDEVNAVRDVVTRVWPEGIKDVRPYGGATEIKCRGWPFSSGQFNGDDNSRRMILRIVNVLFDMGWVLQTTLDMSNKEYDKDALFFRRQSPPPPPCDWIIMSFDTYSKTKVIGDLPPELASGLMQVFQATGNLKRHEFAGDRLKIHLHGYPWAADGQATVATRMTIIRVLECMEAFGFSVYTSLDMTCGQEGRETDVMICCRQKGWVQGQPVWHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N400</accession>
    <name>G4N400_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711729.1">
        <property type="nucleotide sequence ID" value="XM_003711681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N400"/>
    <dbReference type="GeneID" id="12984194"/>
    <dbReference type="KEGG" id="mgr:MGG_16712"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16712"/>
    <dbReference type="HOGENOM" id="CLU_1073908_0_0_1"/>
    <dbReference type="InParanoid" id="G4N400"/>
    <dbReference type="OrthoDB" id="10592288at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465709" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="27805" checksum="535813C1BA441046" modified="2011-12-14" version="1">MAPSSNLLLSFFLPSLLSFLFLGEPGKDSLGTPSNPWRNPAPCLLGLCRARCAWSAACSVASSVVGTRCEGVGVCKLGRPAVPLPLFPATARDGKELRGLTVLGTLLCPCPGLLEREKVRKNRLGKVLDLVPNYSHPNASKGKCASRPSDLVHAGFWSRKQAFLLVIIDVLQQAPGLGNWPGDHCNFKTSVSASKNWTLRQATSPVVPLSIGKEVSLYLTPRRHQRVRCSLEKSRPGDFDGDRVGAEKGAGWLAKLLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4P6</accession>
    <name>G4N4P6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]</fullName>
            <ecNumber evidence="3">1.3.1.124</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_05138</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:45912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:85101"/>
            <dbReference type="ChEBI" id="CHEBI:85493"/>
            <dbReference type="EC" id="1.3.1.124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (2E,4Z)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:61892"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:85099"/>
            <dbReference type="ChEBI" id="CHEBI:85493"/>
            <dbReference type="EC" id="1.3.1.124"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.3.1.124" evidence="3"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712668.1">
        <property type="nucleotide sequence ID" value="XM_003712620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4P6"/>
    <dbReference type="SMR" id="G4N4P6"/>
    <dbReference type="FunCoup" id="G4N4P6">
        <property type="interactions" value="253"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N4P6"/>
    <dbReference type="GeneID" id="2675652"/>
    <dbReference type="KEGG" id="mgr:MGG_05138"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05138"/>
    <dbReference type="eggNOG" id="KOG0725">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_1"/>
    <dbReference type="InParanoid" id="G4N4P6"/>
    <dbReference type="OMA" id="MQAHVCA"/>
    <dbReference type="OrthoDB" id="2136131at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008670">
        <property type="term" value="F:2,4-dienoyl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05369">
        <property type="entry name" value="TER_DECR_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045017">
        <property type="entry name" value="DECR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43296">
        <property type="entry name" value="PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43296:SF2">
        <property type="entry name" value="PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00026117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA52861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="313" mass="32583" checksum="B4F52BC1ED370735" modified="2011-12-14" version="1">MATEYMSGVWKDGIFKDRVIFVTGGAGDICSAQTKAIVHLGANACIIGRNVEKTERVAREIAQVRPGAKVIGIGAVDVRKFEDLKKAADRCASELGAIDFVIAGAAGNFVAPISALTPNGFKSVIDIDTIGTFNTIKATMPHLVASASRNPNPSPTGQTGGRIIYVSATFHYTGVPLQAHVSAAKAGVDSLMASVAIEYGPLGITSNVISPGGIEGTEGMERLSSGEVNKDPKLGAAGVPTGRWGTKRDIGDATVFLFSEAGNYVNGHCLVVDGAAWRGTNAGVGLDPGMRYPDFIISGEFSKNIKSGRKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4R6</accession>
    <name>G4N4R6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glyoxylate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_12929</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712688.1">
        <property type="nucleotide sequence ID" value="XM_003712640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4R6"/>
    <dbReference type="SMR" id="G4N4R6"/>
    <dbReference type="FunCoup" id="G4N4R6">
        <property type="interactions" value="455"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N4R6"/>
    <dbReference type="GeneID" id="5048860"/>
    <dbReference type="KEGG" id="mgr:MGG_12929"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12929"/>
    <dbReference type="eggNOG" id="KOG0069">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_2_1"/>
    <dbReference type="InParanoid" id="G4N4R6"/>
    <dbReference type="OMA" id="PHIAWAY"/>
    <dbReference type="OrthoDB" id="9991913at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12168">
        <property type="entry name" value="Mand_dh_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000282">
        <property type="entry name" value="Glyoxylate reductase protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050223">
        <property type="entry name" value="D-isomer_2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996">
        <property type="entry name" value="2-HYDROXYACID DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10996:SF269">
        <property type="entry name" value="HYPOTHETICAL D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="65"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="127"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="342" mass="35959" checksum="904A3083814B3047" modified="2011-12-14" version="1">MAGESTGTRPKVLLLGTIDHADEAWSKLSAKADIVTPTSTDRASFLAECASGAFAGVVAAYRTFVSGRTTGRIDAELLAALPPTLRFICHNGAGYDQIDVAACTAAGVRVSNTPSAVDDATADAGIFLMLGALRNFGPGMQSCRNGEWIGKPAPALGHDPRGKVLGILGMGGIGRNMAKKAAVFGMKIRYYNRTRLSAELEADCGAEYVDFDTLLVTSDVLSLNLPLNPKTRHTISHAEFAKMKTGVVVVNTARGAVMDEAALVAALDSGRVASAGLDVYEEEPKVHPGLLANHRCLLVPHMGTYTEETQTKMEEVAISNVVAALEKGQLVTGVPEQSGLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N500</accession>
    <name>G4N500_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712718.1">
        <property type="nucleotide sequence ID" value="XM_003712670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N500"/>
    <dbReference type="SMR" id="G4N500"/>
    <dbReference type="FunCoup" id="G4N500">
        <property type="interactions" value="93"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N500"/>
    <dbReference type="GeneID" id="2675358"/>
    <dbReference type="KEGG" id="mgr:MGG_05179"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05179"/>
    <dbReference type="eggNOG" id="KOG4288">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055314_1_0_1"/>
    <dbReference type="InParanoid" id="G4N500"/>
    <dbReference type="OMA" id="WERADIF"/>
    <dbReference type="OrthoDB" id="276721at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF16">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="276" mass="29612" checksum="3AAF1FC1E7DF7327" modified="2011-12-14" version="1">MSAAKAAAKRLVVCGGNGFLGSRICKYGVTRGWDVISISRSGEPHWASVGPTASPPPWAHQVSWERADIFQPEAWAPLVKGADYVVHSMGILLEADYKGAISGRENPVQGLKKAFAAKPPSDPRQLTYEMMNRDSAITLAREASKANVGAFAYISAAGNAPVLPARYLSTKREAESTIASEFPRMRSVFIRAPFLYDTSRLFTVPMAALTGLGTLFNRTTGGVFGNFLGAAAIKPLKAEDVAAAVIEALSEEDVRGPIEVAEIEELANKGWRKGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N608</accession>
    <name>G4N608_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06624</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716903.1">
        <property type="nucleotide sequence ID" value="XM_003716855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N608"/>
    <dbReference type="GeneID" id="2684779"/>
    <dbReference type="KEGG" id="mgr:MGG_06624"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06624"/>
    <dbReference type="eggNOG" id="ENOG502SIIN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_0_1_1"/>
    <dbReference type="InParanoid" id="G4N608"/>
    <dbReference type="OMA" id="FLCDPIS"/>
    <dbReference type="OrthoDB" id="3529975at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF47">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="33"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="281"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="372" mass="41574" checksum="A3D8A1790304D399" modified="2011-12-14" version="1">MADMIPIPMTAAARDALVAAIVLCIMYAIIVGLRVIGRLRWGILGLDDILSVAACILTMTTIGMSTAVYTAGVGYDLDPKSPYFPTLYNNLEYILKNTFAFVGVYLWALAFMKLSQCCLYWRVFVTQLKWWIIWTSIIVLIWAIVLTFIAIFLCTPVEAQWSVDRKPEQCMDQILVLKTLIMTNVVTDLFIMLLPIWTVWQLNMKAAEKATVICCFGLGTGCCIIGIVRFVEMFTIDLQGNLTGTSLRTFMLCAIELCLAGFCTNLPMLRPYYRRWRNRHAPNGSSSGGGSRSMGKEVDGSGSRVPWTDRIIGGQRQQQNHQAWVELDATRDRSNTKSNDDGDSSVRALTKDSDGAGHGGIQMTTEWKVDRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6S7</accession>
    <name>G4N6S7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_13484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716213.1">
        <property type="nucleotide sequence ID" value="XM_003716165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6S7"/>
    <dbReference type="SMR" id="G4N6S7"/>
    <dbReference type="STRING" id="242507.G4N6S7"/>
    <dbReference type="GeneID" id="2676595"/>
    <dbReference type="KEGG" id="mgr:MGG_13484"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13484"/>
    <dbReference type="eggNOG" id="ENOG502S1EZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056292_0_1_1"/>
    <dbReference type="InParanoid" id="G4N6S7"/>
    <dbReference type="OMA" id="IFRDVMA"/>
    <dbReference type="OrthoDB" id="421671at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025638">
        <property type="entry name" value="DUF4336"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835:SF1">
        <property type="entry name" value="METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33835">
        <property type="entry name" value="YALI0C07656P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14234">
        <property type="entry name" value="DUF4336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="39235" checksum="2222EFE505001A24" modified="2011-12-14" version="1">MRAPLARLIYRSPLTADVVPLKPFVPKLILPVACRQQSTRATLPGSGSRNRRLLGTTTASLGALGIVYYYSVGTMSSKLIPDNPAEVMVIRNITPNIVTLSVPFKRFGRFDIGGRGTIVRLTSGSLAVFSPVALTPDVKAKVAEMGGKLEYIVATDIEHHIFVSDWKQEYPDAHILGPEGLPEKRAKVHDDERIGKEAFHTVFTTADKGKQTVTPEFDADFTHEFVDAHPNKELVFLYRPDRVLIQADMLFNLPAVEQYSRVPEEAKPKNGLLNKFFTSMNSTAGDAMGIKRFLWYAISSKDRDGFNKSVQRINEWDFVTIVPCHGETMEGNGKEIFEKVFEWHLKGTKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2024-01-24" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6V4</accession>
    <name>G4N6V4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17176</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717037.1">
        <property type="nucleotide sequence ID" value="XM_003716989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6V4"/>
    <dbReference type="GeneID" id="12985550"/>
    <dbReference type="KEGG" id="mgr:MGG_17176"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17176"/>
    <dbReference type="InParanoid" id="G4N6V4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="90" mass="9854" checksum="D45A4D53CD356240" modified="2011-12-14" version="1" fragment="single">VWGWRDPDVGGSRFRGTHHRTDECLPVEVDGAGPICPEPVSEGGPTLRQPTEIGFCGEGKRVSVLFARDLIRRCLQRPSCKAPPESVLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N712</accession>
    <name>G4N712_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Adenylosuccinate lyase</fullName>
            <shortName evidence="12">ASL</shortName>
            <ecNumber evidence="6 12">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_03645</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = fumarate + AMP</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="6 12"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716244.1">
        <property type="nucleotide sequence ID" value="XM_003716196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N712"/>
    <dbReference type="SMR" id="G4N712"/>
    <dbReference type="FunCoup" id="G4N712">
        <property type="interactions" value="716"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N712"/>
    <dbReference type="GeneID" id="2676630"/>
    <dbReference type="KEGG" id="mgr:MGG_03645"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03645"/>
    <dbReference type="eggNOG" id="KOG2700">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030949_1_1_1"/>
    <dbReference type="InParanoid" id="G4N712"/>
    <dbReference type="OMA" id="VQENAMK"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03302">
        <property type="entry name" value="Adenylsuccinate_lyase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000005">
        <property type="entry name" value="Adenylosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172:SF1">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 12" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenylosuccinate lyase C-terminal" evidence="13">
        <location>
            <begin position="374"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA49925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="485" mass="54409" checksum="2FF6C9BAD44366FE" modified="2011-12-14" version="1">MPDYDSYQTPLGMRYASREMLTLFSPRSRNNTWRQLWIHLAEAEHELGLPQVTQEKIDELKAHAHVTDEAFEVIKAEEKIRRHDVMAAVHAYGKEAPGAAGIIHLGATSCYVTDNAELIFIKKGLELLLPKLAKVISNLQKFALKYKDLPTLGYTHLQPAQLITVGKRVCQWIQELTMDLEDIEHVLSALKLRGIQGTTGTKASFMELFQGDEVKVNKLNDILCKKLGFQGVYDISTQTYTRKVDLRVANALSAFGATAERIGLDIRHLANWKEIEEPFEAGQIGSSAMAYKRNPMRSERITSLGRKLSTLSVNFTKTFEVQMMERTLDDSAIRRIDIPEMFLLADAILISLDNVTDGLVVYPATVRSRVMQELPFMATENIIMKMVAQGASRQECHEEIRVLSHQASHAVKMEGKSNDLLERIKNTEYFKPVHAELDAMLDPALFTGCSQSIVERYCGPDGTVEKALAPYKEHIASAATAELSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7M3</accession>
    <name>G4N7M3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuole morphology and inheritance protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03568</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAC14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716347.1">
        <property type="nucleotide sequence ID" value="XM_003716299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7M3"/>
    <dbReference type="FunCoup" id="G4N7M3">
        <property type="interactions" value="879"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7M3"/>
    <dbReference type="GeneID" id="2676958"/>
    <dbReference type="KEGG" id="mgr:MGG_03568"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03568"/>
    <dbReference type="eggNOG" id="KOG0212">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007740_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7M3"/>
    <dbReference type="OMA" id="QCYQHVS"/>
    <dbReference type="OrthoDB" id="5574975at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021841">
        <property type="entry name" value="VAC14_Fig4p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11916">
        <property type="entry name" value="Vac14_Fig4_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="5">
        <location>
            <begin position="86"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein 14 C-terminal Fig4-binding" evidence="7">
        <location>
            <begin position="599"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="284"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="434"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="828"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA50028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="910" mass="100252" checksum="685EC2E16EBB087F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7P3</accession>
    <name>G4N7P3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tropomyosin-1 alpha chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_03548</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EHA50048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716367.1">
        <property type="nucleotide sequence ID" value="XM_003716319.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N7P3"/>
    <dbReference type="STRING" id="242507.G4N7P3"/>
    <dbReference type="GeneID" id="2676625"/>
    <dbReference type="KEGG" id="mgr:MGG_03548"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03548"/>
    <dbReference type="eggNOG" id="ENOG502R0AV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002168_1_0_1"/>
    <dbReference type="InParanoid" id="G4N7P3"/>
    <dbReference type="OMA" id="FIAVYQH"/>
    <dbReference type="OrthoDB" id="10255000at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012943">
        <property type="entry name" value="Cnn_1N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019528">
        <property type="entry name" value="PACT_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07989">
        <property type="entry name" value="Cnn_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10495">
        <property type="entry name" value="PACT_coil_coil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomin N-terminal motif 1" evidence="8">
        <location>
            <begin position="174"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Pericentrin/AKAP-450 centrosomal targeting" evidence="9">
        <location>
            <begin position="1491"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="468"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="573"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="168"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
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            <end position="915"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="940"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1157"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1217"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1457"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="468"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA50048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1645" mass="189376" checksum="6BEB0D0A1D0AE6EA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7Z3</accession>
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        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
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    </protein>
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        <name evidence="5" type="ORF">MGG_03506</name>
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    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003716366.1"/>
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    <dbReference type="AlphaFoldDB" id="G4N7Z3"/>
    <dbReference type="SMR" id="G4N7Z3"/>
    <dbReference type="STRING" id="242507.G4N7Z3"/>
    <dbReference type="GeneID" id="2676436"/>
    <dbReference type="KEGG" id="mgr:MGG_03506"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03506"/>
    <dbReference type="eggNOG" id="ENOG502S58E">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050545_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7Z3"/>
    <dbReference type="OMA" id="HYYLFVE"/>
    <dbReference type="OrthoDB" id="272703at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
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    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
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        <location>
            <begin position="17"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
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            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="257"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA50095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="295" mass="32072" checksum="E63043C3215684F8" modified="2011-12-14" version="1">MSFASQQNNNAAQSEGRRIYIGNLNYELQSSDVEGMLQQSGFPNYEAVKIPVDPGSQRNRGYCFVDFTTADEAQRSLSELQAVIGGREIKVRPCEPKQQGGGGGFNGGGGFNGGYQQNAGGYNGGYQNAGGYNGGYQQNSGGFNGGGYQNNSYGQQQRYGGGGGYQDNRDVRKLYVGGLGPQPEQEQNEQEVMQIFQGFTPSSISKRLESNRANADGQQNNYYFCFVEFETPEEANAAKDQLDGRVYGAEGNQLRVSFAKPSRSQGQGGQQQQRWPRQQQQGGGGGFGNQGNWRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G4N897</accession>
    <name>G4N897_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03463</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716463.1">
        <property type="nucleotide sequence ID" value="XM_003716415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N897"/>
    <dbReference type="SMR" id="G4N897"/>
    <dbReference type="GeneID" id="2676838"/>
    <dbReference type="KEGG" id="mgr:MGG_03463"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03463"/>
    <dbReference type="eggNOG" id="ENOG502RUEA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007426_4_0_1"/>
    <dbReference type="InParanoid" id="G4N897"/>
    <dbReference type="OMA" id="LANMILC"/>
    <dbReference type="OrthoDB" id="4934715at2759"/>
    <dbReference type="PHI-base" id="PHI:5599"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050613">
        <property type="entry name" value="Sec_Metabolite_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001">
        <property type="entry name" value="UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31001:SF49">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="5">
        <location>
            <begin position="32"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="131"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="617"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="687"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="618"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="687"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="698"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="825" mass="93131" checksum="204527EA04D99652" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8M0</accession>
    <name>G4N8M0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gylcosyl hydrolase 115 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_03407</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716533.1">
        <property type="nucleotide sequence ID" value="XM_003716485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8M0"/>
    <dbReference type="SMR" id="G4N8M0"/>
    <dbReference type="GeneID" id="2676566"/>
    <dbReference type="KEGG" id="mgr:MGG_03407"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03407"/>
    <dbReference type="eggNOG" id="ENOG502QTU7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004852_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8M0"/>
    <dbReference type="OMA" id="QTWVLYK"/>
    <dbReference type="OrthoDB" id="4849794at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.520">
        <property type="entry name" value="Glycosyl hydrolase family 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031924">
        <property type="entry name" value="GH115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041437">
        <property type="entry name" value="GH115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042301">
        <property type="entry name" value="GH115_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37842">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37842:SF2">
        <property type="entry name" value="GYLCOSYL HYDROLASE 115 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17829">
        <property type="entry name" value="GH115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15979">
        <property type="entry name" value="Glyco_hydro_115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466252" description="Gylcosyl hydrolase 115 C-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="Gylcosyl hydrolase 115 C-terminal" evidence="4">
        <location>
            <begin position="785"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="532"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA50214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="962" mass="105776" checksum="EA5EBFA18E1D778D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8M1</accession>
    <name>G4N8M1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Iron-sulfur clusters transporter ATM1, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Iron-sulfur clusters transporter atm1, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_03406</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716534.1">
        <property type="nucleotide sequence ID" value="XM_003716486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8M1"/>
    <dbReference type="SMR" id="G4N8M1"/>
    <dbReference type="FunCoup" id="G4N8M1">
        <property type="interactions" value="686"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N8M1"/>
    <dbReference type="GeneID" id="2676565"/>
    <dbReference type="KEGG" id="mgr:MGG_03406"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03406"/>
    <dbReference type="eggNOG" id="KOG0057">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_1"/>
    <dbReference type="InParanoid" id="G4N8M1"/>
    <dbReference type="OMA" id="VFHIIPI"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140466">
        <property type="term" value="P:iron-sulfur cluster export from the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18582">
        <property type="entry name" value="ABC_6TM_ATM1_ABCB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03253">
        <property type="entry name" value="ABCC_ATM1_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000004">
        <property type="entry name" value="ATP-binding cassette sub-family B member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000186">
        <property type="entry name" value="ATP-binding cassette sub-family B member 7, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF402">
        <property type="entry name" value="IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="17">
        <location>
            <begin position="115"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="439"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00039906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00040792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA50215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="700" mass="77361" checksum="E9C7F032C2E9F345" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8S1</accession>
    <name>G4N8S1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717386.1">
        <property type="nucleotide sequence ID" value="XM_003717338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8S1"/>
    <dbReference type="GeneID" id="12986517"/>
    <dbReference type="KEGG" id="mgr:MGG_17221"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17221"/>
    <dbReference type="HOGENOM" id="CLU_1454706_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8S1"/>
    <dbReference type="OrthoDB" id="5257421at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="186" mass="19888" checksum="86E65CAFA3BA42C6" modified="2011-12-14" version="1">MTPPNISHLIDSRSSNLLREATALELDGVKVAIYIEYDGLTKCFVTDENFQPNWNAEPDAKITIAPTQISNEEEYKHGGSLSSDFASSSAFGSPAFSAPNSDMVRAELPLESGSFTQSNPSICVFGTPVLDSVESPSRAALCDSDTLLFGFCGISSTLFCIVKIRFPSCFAAAELLLLCGGLCGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8Z1</accession>
    <name>G4N8Z1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03348</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716604.1">
        <property type="nucleotide sequence ID" value="XM_003716556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8Z1"/>
    <dbReference type="SMR" id="G4N8Z1"/>
    <dbReference type="FunCoup" id="G4N8Z1">
        <property type="interactions" value="962"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N8Z1"/>
    <dbReference type="GeneID" id="2676480"/>
    <dbReference type="KEGG" id="mgr:MGG_03348"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03348"/>
    <dbReference type="eggNOG" id="KOG2493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015355_3_0_1"/>
    <dbReference type="InParanoid" id="G4N8Z1"/>
    <dbReference type="OMA" id="MQAFCIA"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="569"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="299"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="603" mass="65453" checksum="E5DD5D9BFFEEBAE4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8Z5</accession>
    <name>G4N8Z5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717409.1">
        <property type="nucleotide sequence ID" value="XM_003717361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8Z5"/>
    <dbReference type="GeneID" id="12986523"/>
    <dbReference type="KEGG" id="mgr:MGG_17225"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17225"/>
    <dbReference type="HOGENOM" id="CLU_2373197_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8Z5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="95" mass="10632" checksum="AD41F765C459B888" modified="2011-12-14" version="1">MWNLFLSRFSKAWVVVPVTNLDLCDEAFVSVISKMTRQDRIFKAGSNSGAVSHRQLRQLRTIPWVHDNGPSGLLHVRTARWWSGPQLGSGEGRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N925</accession>
    <name>G4N925_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10066</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717439.1">
        <property type="nucleotide sequence ID" value="XM_003717391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N925"/>
    <dbReference type="STRING" id="242507.G4N925"/>
    <dbReference type="GeneID" id="2681677"/>
    <dbReference type="KEGG" id="mgr:MGG_10066"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10066"/>
    <dbReference type="eggNOG" id="ENOG502RNHV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_888709_0_0_1"/>
    <dbReference type="InParanoid" id="G4N925"/>
    <dbReference type="OMA" id="PRCFQIM"/>
    <dbReference type="OrthoDB" id="5243605at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466283" evidence="2">
        <location>
            <begin position="21"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="313" mass="29243" checksum="A831AFDADAF17895" modified="2011-12-14" version="1">MLRNVCLLVILGLAPALIAASPVPGGDYGYGGSSGGGGGSVSPGGPSGPGGGGAGGPQGPGGPSGPGGPGGPGGPGGPKGSGGPGGPGGPGGPGGPGGPGGPSGPGGKGGVQLPGSNGGVKLPPGQGGVRFPSGQDGAVNCDYPSNRNNPACTTTNSGGNTPVCGNVNPCANMASGPGAGPNAMCVNCDYPSNAGNFACKSNTGMQANCNLSQFANLSICGGSCPDNNTPTPTPSNNSPPPSNETPTPIPTDVAPASTVTPTPEPTPTDYSPEPSATDSSPATATDNSPAPTSTNSDYNDDSGDYSVSDDYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N944</accession>
    <name>G4N944_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">N-acetyltransferase ESCO zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716607.1">
        <property type="nucleotide sequence ID" value="XM_003716559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N944"/>
    <dbReference type="GeneID" id="12984524"/>
    <dbReference type="KEGG" id="mgr:MGG_17111"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17111"/>
    <dbReference type="eggNOG" id="ENOG502RW0X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067371_0_0_1"/>
    <dbReference type="InParanoid" id="G4N944"/>
    <dbReference type="OMA" id="TKPGLHH"/>
    <dbReference type="OrthoDB" id="5231968at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028005">
        <property type="entry name" value="AcTrfase_ESCO_Znf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13878">
        <property type="entry name" value="zf-C2H2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase ESCO zinc-finger" evidence="2">
        <location>
            <begin position="236"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="283" mass="31224" checksum="C5D30B422C11CD21" modified="2011-12-14" version="1">MNPRPSMATEDIATTAETSLPPRRRPLRTYGKRKAVIERDSDKPQPKRIRVPEAIQATEPRGHPPRIELPFEESCIYVRTSPTPSPSPSPSPSASPAKKAPKSSILRYFKKTAATPAPLPSPTRSQTADHSETPSSPVISPPPKRSLRAPRRLTTRPSRIIDARDDSPSDSIHDTNRSTETLDADQFSPGNVRTTIKEDSANPRRTKPCDCQFKPCSHQNKPGSRRAVKSPTSTIQMTLSLSARSSSITQCRECDMLYNPLHPSDVKNHSRHHAALAKIKAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4N956</accession>
    <name>G4N956_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716619.1">
        <property type="nucleotide sequence ID" value="XM_003716571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N956"/>
    <dbReference type="GeneID" id="12984528"/>
    <dbReference type="KEGG" id="mgr:MGG_17114"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17114"/>
    <dbReference type="HOGENOM" id="CLU_2776423_0_0_1"/>
    <dbReference type="InParanoid" id="G4N956"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="69" mass="7991" checksum="366883A6FFD692EA" modified="2011-12-14" version="1">MLNDSWFLFFPFSPLFSLSQDNASKKYSQLSFSYNSKQINTLDTCTNAKILFQSCRTFVCSFSIAEKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N989</accession>
    <name>G4N989_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_03309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716652.1">
        <property type="nucleotide sequence ID" value="XM_003716604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N989"/>
    <dbReference type="GeneID" id="2676455"/>
    <dbReference type="KEGG" id="mgr:MGG_03309"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03309"/>
    <dbReference type="eggNOG" id="ENOG502SM2G">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046577_1_0_1"/>
    <dbReference type="InParanoid" id="G4N989"/>
    <dbReference type="OMA" id="DAVCIAW"/>
    <dbReference type="OrthoDB" id="5365129at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="370" mass="39575" checksum="9AFFC0681C7B29D7" modified="2011-12-14" version="1">MTTIIDIIGVVSGVVGIIQFAQDAFPQKQKPGSSVRIAVGLDASGGLDNAGGNVPGVALFNEVGGFLGQSQKNGQVQDGNFADLTVTQSSGQQATYGLFQAGHDAVCIAYTTITWPDGNQYALTGDWGEACGGSWYYSNIYVQSSGYKPKCMWIDADGNQPQTGFQVHFPEFRSDSSTMPAGKDVKTLCNSKAPFQYFTTAGPQTIDYWNADGKTTSQSTVPSKRDVGSQINRRAAAAARPSAIVITNGTDHSVKELCGSKTSSGPDLFNLIERSSCRMSDKTIFPQCDATVKDNCFNVDSTQLIVGGKAARSPYEVVWDWKTAGKTFTSKVATSAKIAAREPYAKPQEYNNIIDWSVAGKVDIEPVKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4N995</accession>
    <name>G4N995_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716658.1">
        <property type="nucleotide sequence ID" value="XM_003716610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N995"/>
    <dbReference type="GeneID" id="12984567"/>
    <dbReference type="KEGG" id="mgr:MGG_17118"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17118"/>
    <dbReference type="HOGENOM" id="CLU_2740528_0_0_1"/>
    <dbReference type="InParanoid" id="G4N995"/>
    <dbReference type="OrthoDB" id="5206690at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="71" mass="7925" checksum="DBA19F534FE4AD80" modified="2011-12-14" version="1">MADPNEKQKCTYHRNSSKSAPALPRDQKPKTAEREGRINTWLQDDSLSRITYISIGGVKDGKPEKGSPARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9F9</accession>
    <name>G4N9F9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein SDA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_03291</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for 60S pre-ribosomal subunits export to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SDA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716670.1">
        <property type="nucleotide sequence ID" value="XM_003716622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9F9"/>
    <dbReference type="SMR" id="G4N9F9"/>
    <dbReference type="FunCoup" id="G4N9F9">
        <property type="interactions" value="1091"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9F9"/>
    <dbReference type="GeneID" id="2677024"/>
    <dbReference type="KEGG" id="mgr:MGG_03291"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03291"/>
    <dbReference type="eggNOG" id="KOG2229">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009161_2_1_1"/>
    <dbReference type="InParanoid" id="G4N9F9"/>
    <dbReference type="OMA" id="AMYKTYK"/>
    <dbReference type="OrthoDB" id="2196187at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042255">
        <property type="term" value="P:ribosome assembly"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007089">
        <property type="term" value="P:traversing start control point of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027312">
        <property type="entry name" value="Sda1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048292">
        <property type="entry name" value="SDA1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007949">
        <property type="entry name" value="SDA1_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012977">
        <property type="entry name" value="SDA1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730">
        <property type="entry name" value="HSDA/SDA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730:SF0">
        <property type="entry name" value="PROTEIN SDA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21638">
        <property type="entry name" value="SDA1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05285">
        <property type="entry name" value="SDA1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08158">
        <property type="entry name" value="SDA1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SDA1 N-terminal" evidence="9">
        <location>
            <begin position="70"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 middle" evidence="8">
        <location>
            <begin position="546"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 C-terminal" evidence="10">
        <location>
            <begin position="695"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="509"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="668"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="572"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="668"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA50351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="747" mass="84153" checksum="BB31F78DC5ED9BDE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9K7</accession>
    <name>G4N9K7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lipid phosphate phosphatase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_09994</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003717466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9K7"/>
    <dbReference type="STRING" id="242507.G4N9K7"/>
    <dbReference type="GeneID" id="2681017"/>
    <dbReference type="KEGG" id="mgr:MGG_09994"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09994"/>
    <dbReference type="eggNOG" id="KOG3030">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021458_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9K7"/>
    <dbReference type="OMA" id="RSFWDTN"/>
    <dbReference type="OrthoDB" id="10030083at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF84">
        <property type="entry name" value="PHOSPHATIDIC ACID PHOSPHATASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="154"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="405"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA51195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="444" mass="49052" checksum="BBDA3D2563FCFE77" modified="2011-12-14" version="1">MVSLPPMFNRRRRHHDGPELPTHNKHSSSGRRDSSATRVLAEEYSMRRRPSIKLWIKLHWLDLLTMAIFGAITLGIFQAPLITHRPFPVRFNSNSDGSFSSFGDIVYPEFAYPHRPQIVPNWAATIAAMFFPILVMALAQIRVRSFWDFSNGVIGLLNALVLSTFCQILLKWLIGGLRPNFYDTCKPDLSLAASRNESGTEGIGYGGIMYTTKICTGDKKDIDNALESWPSGHTTAAFAGFVYLSLYLNAKLKVFANHHPALWKLALAYFPILCAVLIAGSLSVDGSHNWYDILTGMVIGITFALSAYRSVYASVWNWRTNHIPLHRGLPFGEDEEDVVGMRWTMTRKAGWGRRTKAKGMRFGKKKRGTDGGVVGGEKHAADLGHGNGMAPANHYEGNNLNNLNNGNNGTEFGAGPAAPGSAAMRHDPGVPTQHEVRRGGDNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9P0</accession>
    <name>G4N9P0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09964</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717547.1">
        <property type="nucleotide sequence ID" value="XM_003717499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9P0"/>
    <dbReference type="GeneID" id="2680950"/>
    <dbReference type="KEGG" id="mgr:MGG_09964"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09964"/>
    <dbReference type="HOGENOM" id="CLU_377700_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9P0"/>
    <dbReference type="OMA" id="VQITHER"/>
    <dbReference type="OrthoDB" id="5237318at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="475"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="660"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="515"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="552"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="566"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="576"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="612"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="630"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="734" mass="82576" checksum="E3BC71632FDC7648" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA59</accession>
    <name>G4NA59_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_13937</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715928.1">
        <property type="nucleotide sequence ID" value="XM_003715880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA59"/>
    <dbReference type="SMR" id="G4NA59"/>
    <dbReference type="STRING" id="242507.G4NA59"/>
    <dbReference type="GeneID" id="5049258"/>
    <dbReference type="KEGG" id="mgr:MGG_13937"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13937"/>
    <dbReference type="eggNOG" id="ENOG502S31Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035914_2_0_1"/>
    <dbReference type="InParanoid" id="G4NA59"/>
    <dbReference type="OMA" id="DGCITDG"/>
    <dbReference type="OrthoDB" id="6132182at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466242" description="Tyrosinase copper-binding domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="6">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="257"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA49609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="326" mass="35309" checksum="9B1D507AF9FDFA1F" modified="2011-12-14" version="1">MSLNKVAHLILAGTSLLLVAGEPCTNPGQRHAWHTLNNADKKAYIDAELCLMAKPASLGLPGTRTKFDELQAIHQLQAYSTHHVGAFLPFHRLMMHAHETALRDDCGYTGRQPYWQEQLDAGRFSGSVVFDAATGFGGDGSGRDGCITDGPFANYTNSLGPGYAVTDHCIDRAIGDSVSTLSSQDNVDGCVGQTTWERAWACIESLPHVGGHAGVGRQMANGVSSPGDPLFYLHHTWLDKIYWDWQARDRAVRTTTISGGNVMPDDMPGFPPRPSNIPQPTGAPGDPGTETTLGHVLNMYGNLPNKTISDVLDIQGDYLCYEYVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAC3</accession>
    <name>G4NAC3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_03198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716787.1">
        <property type="nucleotide sequence ID" value="XM_003716739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAC3"/>
    <dbReference type="SMR" id="G4NAC3"/>
    <dbReference type="FunCoup" id="G4NAC3">
        <property type="interactions" value="595"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAC3"/>
    <dbReference type="GeneID" id="2676471"/>
    <dbReference type="KEGG" id="mgr:MGG_03198"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03198"/>
    <dbReference type="eggNOG" id="KOG0273">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018409_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAC3"/>
    <dbReference type="OMA" id="VNFLIWR"/>
    <dbReference type="OrthoDB" id="1367865at2759"/>
    <dbReference type="PHI-base" id="PHI:2002"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045183">
        <property type="entry name" value="Ebi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846:SF2">
        <property type="entry name" value="F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
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    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAS2</accession>
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        <submittedName>
            <fullName evidence="6">Pumilio-family RNA binding repeat protein</fullName>
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        <name evidence="6" type="ORF">MGG_03158</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    </reference>
    <comment type="function">
        <text evidence="2">RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit.</text>
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        <property type="component" value="Chromosome 4"/>
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    <dbReference type="GO" id="GO:0005737">
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    <dbReference type="GO" id="GO:0003730">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
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        <property type="entry name" value="PUM-HD"/>
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        <property type="entry name" value="Pumilio_RNA-bd"/>
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        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
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    <dbReference type="PANTHER" id="PTHR12537:SF48">
        <property type="entry name" value="MEIOTIC COILED-COIL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="8"/>
    </dbReference>
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        <property type="match status" value="8"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
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            <end position="774"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="485"/>
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        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA50514.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAY8</accession>
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            <fullName evidence="12">mRNA 3'-end-processing protein</fullName>
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    </protein>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CPSF4/YTH1 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003718286.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NAY8"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_00680"/>
    <dbReference type="eggNOG" id="KOG1040">
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    <dbReference type="HOGENOM" id="CLU_024513_1_0_1"/>
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        <property type="component" value="Chromosome 5"/>
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    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="cleavage and polyadenylation specificity factor subunit 4"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
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    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 12" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="11">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="222"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="224"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008907"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00024826"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU369008"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA48750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="276" mass="30234" checksum="11D8EFD0D54340DE" modified="2011-12-14" version="1">MASPSVAKIADAMLAHSAPKYSFSFTPFLQQTYQHSLPSDRPICKVYASGGNCPNGTRCLERHVADPSQLSNAQSGYGSGKRDGPAFNSLVCKHWLRGLCKKGDGCEFLHEYNLRRMPECNFYIRNGYCQNGEECLYLHIDPQSKLPPCPHYDQGFCPLGPRCSKKHVRRNLCPYYLCGFCPDGRLCKQGAHPGWNPKLDPPTVKVEKPAGEEDAMGFAARGGAYDDHEDGDRGGQQRGDRRGGYGQRDGKFGGGGGGGRGGWRGRGGGHRGRGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBA4</accession>
    <name>G4NBA4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein HIR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_00590</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003718402.1"/>
    </dbReference>
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    <dbReference type="SMR" id="G4NBA4"/>
    <dbReference type="FunCoup" id="G4NBA4">
        <property type="interactions" value="159"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NBA4"/>
    <dbReference type="GeneID" id="2675167"/>
    <dbReference type="KEGG" id="mgr:MGG_00590"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00590"/>
    <dbReference type="eggNOG" id="KOG0973">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004372_3_1_1"/>
    <dbReference type="InParanoid" id="G4NBA4"/>
    <dbReference type="OMA" id="RGSWDGD"/>
    <dbReference type="OrthoDB" id="1741719at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000290">
        <property type="entry name" value="Protein HIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001557">
        <property type="entry name" value="Protein HIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055410">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011494">
        <property type="entry name" value="HIRA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019015">
        <property type="entry name" value="HIRA_B_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24105">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07569">
        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09453">
        <property type="entry name" value="HIRA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 11 12" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="CAF1B/HIR1 beta-propeller" evidence="15">
        <location>
            <begin position="28"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="66"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="127"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="169"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="14">
        <location>
            <begin position="754"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="440"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF24105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA48866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1073" mass="116608" checksum="04138B4D287C770A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBM8</accession>
    <name>G4NBM8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717717.1">
        <property type="nucleotide sequence ID" value="XM_003717669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBM8"/>
    <dbReference type="GeneID" id="12986612"/>
    <dbReference type="KEGG" id="mgr:MGG_17305"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17305"/>
    <dbReference type="HOGENOM" id="CLU_2292252_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBM8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="101" mass="11181" checksum="B1D1499A4E990BEB" modified="2011-12-14" version="1">MVSFWVTLLSRSSLNLRLDSIFMPLEPVTGGTQNKLPPINRVFSTAPTSASQNHKRMIGGGLLGQKRQHLRRLTAWCKQIPHTWGLGVAATANNNTLRIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC36</accession>
    <name>G4NC36_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718623.1">
        <property type="nucleotide sequence ID" value="XM_003718575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC36"/>
    <dbReference type="GeneID" id="2674508"/>
    <dbReference type="KEGG" id="mgr:MGG_00445"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00445"/>
    <dbReference type="eggNOG" id="KOG2132">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054409_0_0_1"/>
    <dbReference type="InParanoid" id="G4NC36"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="202"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="369" mass="41135" checksum="5B363BE8846AD7C7" modified="2011-12-14" version="1">MKPVPWRYLIQGSALDINEISLSHFQQNFFQPGLPVVLRNPLPTSLAGNARSLAPYYEALRPTDGLSKHSGLRLWKQSNILTKGEDEYSCHQPLWQCWDTAFGGNHHTSCPFEIGVSPRQQPGLTHFLLWLRARLPDIPRDDIVDHQLGEQDMQLESLLSTELRSCTPGSSMIRFEGPISLFKLAVMYNHASLSSGGQPLANFYVAQLPIADLPPNLQAALAPPHVVLNAGKGDVYGGSLWMGLTPTKTSWHRDPNPNILSQSVGSKLVRMMPPRSGERVFHDVHSRLGTRNFNSRFRGMELLDGPEATALDDAVWGPDADQMPEMVEATLNPDESLFIPKGWWHSVKSLNPGTAFNGLLNVSVNYWFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND93</accession>
    <name>G4ND93_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718815.1">
        <property type="nucleotide sequence ID" value="XM_003718767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND93"/>
    <dbReference type="SMR" id="G4ND93"/>
    <dbReference type="GeneID" id="2674516"/>
    <dbReference type="KEGG" id="mgr:MGG_00283"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00283"/>
    <dbReference type="eggNOG" id="ENOG502TBZD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1749532_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND93"/>
    <dbReference type="OrthoDB" id="5225074at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466383" description="SnoaL-like domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16073" checksum="985A53886921E69A" modified="2011-12-14" version="1">MRASFFAVAVAAAAVQAAPVIETRQDVPPIPAACTPAPGLDTAATYDKVLAFQKVYLFDKDITETFKYFSADFQSKQRFVTFNRDQYWAVSTVQGWGQTASYPTDSSFSNGRAHVAYDLGPQRTGHAGDDFVWKDGCIISEQQTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEC9</accession>
    <name>G4NEC9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718196.1">
        <property type="nucleotide sequence ID" value="XM_003718148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEC9"/>
    <dbReference type="GeneID" id="12984037"/>
    <dbReference type="KEGG" id="mgr:MGG_17368"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17368"/>
    <dbReference type="InParanoid" id="G4NEC9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="167" mass="18598" checksum="DB2A04D722FE9466" modified="2011-12-14" version="1" fragment="single">YPARSGEAFYWIPGGQLCPYRLQCRTRYSEISAVFVRGETFFGELGSLGQDKKRPDDEKLGPFHHHSEPEIQPHCLAARSRPQEGLSPEKKEWKESDSTASSATCPLRAATPRIIHIDVRMAGVGHPKAFCLDGPRAKRLNKTENSSSYLAQHPGIQNGLDLLAKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEH4</accession>
    <name>G4NEH4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_00104</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the actin-binding proteins ADF family. Coactosin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719035.1">
        <property type="nucleotide sequence ID" value="XM_003718987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEH4"/>
    <dbReference type="SMR" id="G4NEH4"/>
    <dbReference type="STRING" id="242507.G4NEH4"/>
    <dbReference type="GeneID" id="2674841"/>
    <dbReference type="KEGG" id="mgr:MGG_00104"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00104"/>
    <dbReference type="eggNOG" id="KOG3655">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129657_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEH4"/>
    <dbReference type="OMA" id="WIGPNCK"/>
    <dbReference type="OrthoDB" id="20822at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000018">
        <property type="entry name" value="Coactosin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF56">
        <property type="entry name" value="ADF-H DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="3"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA49451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="147" mass="16526" checksum="58FF6F68DADFA073" modified="2011-12-14" version="1">MNAVNVDTPEIRAAYDAVRSDKDSTNWLLLTPSGKEAELTTGTEGWDEFVSKLDDAKDQYGYARVEYANDSESTRTKFVLVIWNGKNVEGNIGKRRFGIINQKNAVMRVMNHYSLDIQTEDKSDLKKDDVVKELRRTGGADYNGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF12</accession>
    <name>G4NF12_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003719067.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NF12"/>
    <dbReference type="STRING" id="242507.G4NF12"/>
    <dbReference type="GeneID" id="5050853"/>
    <dbReference type="KEGG" id="mgr:MGG_11693"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11693"/>
    <dbReference type="eggNOG" id="ENOG502SM9E">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022448_0_0_1"/>
    <dbReference type="InParanoid" id="G4NF12"/>
    <dbReference type="OMA" id="VAEFWIM"/>
    <dbReference type="OrthoDB" id="5313079at2759"/>
    <dbReference type="PHI-base" id="PHI:2198"/>
    <dbReference type="PHI-base" id="PHI:8110"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
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    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
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        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
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    </feature>
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        <location>
            <begin position="374"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49531.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFT1</accession>
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        <recommendedName>
            <fullName evidence="14">DUF221 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="12" type="ORF">MGG_08731</name>
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    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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            <taxon>Pyricularia</taxon>
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    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
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    <dbReference type="GO" id="GO:0005886">
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Csc1-like"/>
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    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="127"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="446"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="532"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="562"/>
            <end position="588"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="630"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="653"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="674"/>
            <end position="694"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="700"/>
            <end position="720"/>
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    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="25"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="195"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="419"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="265"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="742"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="799"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="840"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="747"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA46888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="866" mass="99768" checksum="A1EFBC8716D9B50C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFV8</accession>
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        <submittedName>
            <fullName evidence="10">Candidapepsin-8</fullName>
        </submittedName>
    </protein>
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        <name evidence="10" type="ORF">MGG_08698</name>
    </gene>
    <organism evidence="10 11">
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        <lineage>
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            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719282.1">
        <property type="nucleotide sequence ID" value="XM_003719234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFV8"/>
    <dbReference type="SMR" id="G4NFV8"/>
    <dbReference type="MEROPS" id="A01.082"/>
    <dbReference type="GeneID" id="2678947"/>
    <dbReference type="KEGG" id="mgr:MGG_08698"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08698"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_9_4_1"/>
    <dbReference type="InParanoid" id="G4NFV8"/>
    <dbReference type="OMA" id="CEAVGFY"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466914" evidence="8">
        <location>
            <begin position="24"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="63"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="423"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="435"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA46915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="497" mass="51349" checksum="6F981C23E94D1E7C" modified="2011-12-14" version="1">MAATSIRGLLLLAVAAAAGPLEAAQEPHDPGCLHMPIMHMSKAEQYQKRAVKVPFDQRFDVGYYTKLSFGTPAQEALVHLDTGSFELWINPTCNNLDGAGEQQFCRAGGSYDPAQSTTVQRLGTTNTLRYGIGSANISYVKDTVGIPGTNMSVRSAQFGVATSSETQNAGILGIGHGVGQAIGYRNFIDELKAQNVTKTRAFSVALGGKDEKQGTVVFGGVDTSKFAGGLARLPIIPAAQSPDGVRRYWVNMSSISLHPPSGRNKTYPGTNMPVFLDTGSTLTLLPEALVKSVASDFGSMQQDAGGYWPVDCSLVGINGTMDFAFDGVTIKVPYKELIRQFGNSCVLGLSSHSSFTLLGDTFMRSAYFVFDQDSDCVWMTQYTNCGSTPAALASVASLRTLQGACPLKQGSVSAVTAGTAGAAAPSTTASPKAPGAGGGSGSNGGGGAKGSPPPGASASAPDSKLKNAGGRAMQVPAISSAVVTLVLTTLAALHLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGD9</accession>
    <name>G4NGD9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Proteasome activator subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_04342</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BLM10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719463.1">
        <property type="nucleotide sequence ID" value="XM_003719415.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NGD9"/>
    <dbReference type="FunCoup" id="G4NGD9">
        <property type="interactions" value="323"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGD9"/>
    <dbReference type="GeneID" id="2677535"/>
    <dbReference type="KEGG" id="mgr:MGG_04342"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04342"/>
    <dbReference type="eggNOG" id="KOG1851">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000772_3_0_1"/>
    <dbReference type="InParanoid" id="G4NGD9"/>
    <dbReference type="OMA" id="ECTQLVP"/>
    <dbReference type="OrthoDB" id="17907at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016504">
        <property type="term" value="F:peptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032430">
        <property type="entry name" value="Blm10_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055455">
        <property type="entry name" value="HEAT_PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035309">
        <property type="entry name" value="PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021843">
        <property type="entry name" value="PSME4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170:SF3">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23096">
        <property type="entry name" value="HEAT_PSME4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16507">
        <property type="entry name" value="HEAT_PSME4_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11919">
        <property type="entry name" value="PSME4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Proteasome activator Blm10 middle HEAT repeats region" evidence="11">
        <location>
            <begin position="269"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4-like HEAT repeat-like" evidence="12">
        <location>
            <begin position="1244"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4 C-terminal" evidence="10">
        <location>
            <begin position="1761"/>
            <end position="1849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="809"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1732"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="813"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA47096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1849" mass="211045" checksum="8D8223594AB5975E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGG6</accession>
    <name>G4NGG6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_04320</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719490.1">
        <property type="nucleotide sequence ID" value="XM_003719442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGG6"/>
    <dbReference type="SMR" id="G4NGG6"/>
    <dbReference type="FunCoup" id="G4NGG6">
        <property type="interactions" value="87"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGG6"/>
    <dbReference type="GeneID" id="2677110"/>
    <dbReference type="KEGG" id="mgr:MGG_04320"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04320"/>
    <dbReference type="eggNOG" id="KOG2867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030733_2_0_1"/>
    <dbReference type="InParanoid" id="G4NGG6"/>
    <dbReference type="OMA" id="IHESQDV"/>
    <dbReference type="OrthoDB" id="16120at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="431"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA47123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="493" mass="53483" checksum="99A034979A52CF75" modified="2011-12-14" version="1">MEPPPKPVQLPKLEILPRGKGWKFQAPTKKINDGADVSHFLTSKAYRDICVFVLQLNRSLCPRKKSGAPANAGTVFTLASPRDDPPSVRRLQTLLDKVVAIVDETPPDPGPRRFGNIAFRTWHKHLEDRVDALLAGSIAPEILSFDNDGEQPKADDSAEGKADEHKIISTASAIDELRAYFLGSFGSSQRLDYGTGHELSFLAFLGGLWKLGAFTDGPESDHGDIERSIVLGVFEQYLKVIRKLILTYTLEPAGSHGVWGLDDHSFLPYIFGSAQLTRPISEDETMPLEGSVMRAPKLGDITKVETVEVQRELNMYFSAVGFINDVKKGPFWEHSPMLWDVSGIKDGWGKVNKGMIKMFNAEVLSKFPVVQHFPIGSLFSWEVDPEAPIPTQSVHMQNQPVFAATGQAPMGMPPTGMPPPQLNPMGVSMGTAAPWAQGGRMPAPGISSRVQQPVTGTTRPPPPDPVARQSGGPAAASSGTNDGQAGLTKAPWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGR2</accession>
    <name>G4NGR2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ClpTM1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_04052</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLPTM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719789.1">
        <property type="nucleotide sequence ID" value="XM_003719741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGR2"/>
    <dbReference type="STRING" id="242507.G4NGR2"/>
    <dbReference type="GeneID" id="2677260"/>
    <dbReference type="KEGG" id="mgr:MGG_04052"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04052"/>
    <dbReference type="eggNOG" id="KOG2489">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019907_2_0_1"/>
    <dbReference type="InParanoid" id="G4NGR2"/>
    <dbReference type="OMA" id="TLWAHFY"/>
    <dbReference type="OrthoDB" id="378564at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008429">
        <property type="entry name" value="CLPTM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347">
        <property type="entry name" value="CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347:SF0">
        <property type="entry name" value="LIPID SCRAMBLASE CLPTM1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05602">
        <property type="entry name" value="CLPTM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="521"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="618"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="670" mass="74649" checksum="F892972AC97D1330" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH83</accession>
    <name>G4NH83_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RENT3 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003719912.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NH83"/>
    <dbReference type="STRING" id="242507.G4NH83"/>
    <dbReference type="GeneID" id="2677488"/>
    <dbReference type="KEGG" id="mgr:MGG_03912"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03912"/>
    <dbReference type="eggNOG" id="KOG0116">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018549_0_0_1"/>
    <dbReference type="InParanoid" id="G4NH83"/>
    <dbReference type="OMA" id="QYKPGKV"/>
    <dbReference type="OrthoDB" id="18087at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
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    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12455">
        <property type="entry name" value="RRM_like_Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039722">
        <property type="entry name" value="Upf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005120">
        <property type="entry name" value="UPF3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112:SF0">
        <property type="entry name" value="FI21285P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112">
        <property type="entry name" value="UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03467">
        <property type="entry name" value="Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="495"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="171"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="312"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="566"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="355"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="401"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="578"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="590"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="648"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="676" mass="69726" checksum="9256D84669182555" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHB6</accession>
    <name>G4NHB6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Nuclear envelope protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_17732</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NDC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719993.1">
        <property type="nucleotide sequence ID" value="XM_003719945.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NHB6"/>
    <dbReference type="STRING" id="242507.G4NHB6"/>
    <dbReference type="GeneID" id="12987114"/>
    <dbReference type="KEGG" id="mgr:MGG_17732"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17732"/>
    <dbReference type="eggNOG" id="ENOG502S1MG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="InParanoid" id="G4NHB6"/>
    <dbReference type="OMA" id="WQTANLF"/>
    <dbReference type="OrthoDB" id="67850at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070762">
        <property type="term" value="C:nuclear pore transmembrane ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:spindle pole body-nuclear membrane anchor activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070631">
        <property type="term" value="P:spindle pole body localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019049">
        <property type="entry name" value="Nucleoporin_prot_Ndc1/Nup"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13269">
        <property type="entry name" value="NUCLEOPORIN NDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13269:SF6">
        <property type="entry name" value="NUCLEOPORIN NDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09531">
        <property type="entry name" value="Ndc1_Nup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="621"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA47626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="643" mass="72501" checksum="9AF6E83DC736B8CD" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI56</accession>
    <name>G4NI56_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Asl1-like glycosyl hydrolase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720283.1">
        <property type="nucleotide sequence ID" value="XM_003720235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI56"/>
    <dbReference type="SMR" id="G4NI56"/>
    <dbReference type="GeneID" id="5049774"/>
    <dbReference type="KEGG" id="mgr:MGG_11998"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11998"/>
    <dbReference type="eggNOG" id="ENOG502SJGG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040908_4_0_1"/>
    <dbReference type="InParanoid" id="G4NI56"/>
    <dbReference type="OMA" id="MLWGTQS"/>
    <dbReference type="OrthoDB" id="43654at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071966">
        <property type="term" value="P:fungal-type cell wall polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053183">
        <property type="entry name" value="ASL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024655">
        <property type="entry name" value="Asl1_glyco_hydro_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154">
        <property type="entry name" value="ALKALI-SENSITIVE LINKAGE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34154:SF10">
        <property type="entry name" value="ASL1-LIKE GLYCOSYL HYDROLASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11790">
        <property type="entry name" value="Glyco_hydro_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Asl1-like glycosyl hydrolase catalytic" evidence="2">
        <location>
            <begin position="144"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="381" mass="42810" checksum="A0EED1F42291DA9D" modified="2011-12-14" version="1">MAHNGGTLHRAVVDISDLPTDPEARKAALEKLAKSVQQFSSLVKFIDESAMKKQELQRLTKLEEASKTECPQRRELMKLYATPWPKGFMQFLVKALLLGVVVQEASAALLGSSFGLIILTNFVAIAFFTQGACTAAAMLDAKRGLAFNDGVDISGFSHSAMITWGYNWYSDTWQVTNEIEFGPMLWGIKMDLPDVFSPNAWKWVDSGDQLSGVKTTHVLSFNEPDHPAQANMDVGTAIAWHQYYFEQFIGRALIGSPAVTNGGYDWLNTFLYNCDLHEGCHVDFVTVHWYNKAAYVQDFKNWIDRVCTLAYPRKVWLTEFQGLGTQEEMISFLRVVLPWLDANDCVERYAYFGVTTNDHHMLVGAGPELSQIGEIYAGFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJB5</accession>
    <name>G4NJB5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_12611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721074.1">
        <property type="nucleotide sequence ID" value="XM_003721026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJB5"/>
    <dbReference type="GeneID" id="5050488"/>
    <dbReference type="KEGG" id="mgr:MGG_12611"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12611"/>
    <dbReference type="HOGENOM" id="CLU_486673_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJB5"/>
    <dbReference type="OMA" id="TRYVTIT"/>
    <dbReference type="OrthoDB" id="5245255at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003467005" evidence="2">
        <location>
            <begin position="20"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="560" mass="58095" checksum="AEA587B40D93F69B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NK11</accession>
    <name>G4NK11_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arylsulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720523.1">
        <property type="nucleotide sequence ID" value="XM_003720475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NK11"/>
    <dbReference type="SMR" id="G4NK11"/>
    <dbReference type="STRING" id="242507.G4NK11"/>
    <dbReference type="GeneID" id="2681960"/>
    <dbReference type="KEGG" id="mgr:MGG_10308"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10308"/>
    <dbReference type="eggNOG" id="KOG3867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006332_11_1_1"/>
    <dbReference type="InParanoid" id="G4NK11"/>
    <dbReference type="OMA" id="HYPRGWG"/>
    <dbReference type="OrthoDB" id="4356994at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16025">
        <property type="entry name" value="PAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050738">
        <property type="entry name" value="Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693:SF33">
        <property type="entry name" value="ARYLSULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693">
        <property type="entry name" value="ARYLSULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="3">
        <location>
            <begin position="9"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA45780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="567" mass="63228" checksum="2766F006D802E9A0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH34</accession>
    <name>G5EH34_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Atypical/ABC1/ABC1-B protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGCH7_ch7g352</name>
        <name evidence="6" type="ORF">MGG_02627</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15</strain>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">70-15</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721162.1">
        <property type="nucleotide sequence ID" value="XM_003721114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH34"/>
    <dbReference type="STRING" id="242507.G5EH34"/>
    <dbReference type="GeneID" id="2682826"/>
    <dbReference type="KEGG" id="mgr:MGG_02627"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02627"/>
    <dbReference type="eggNOG" id="KOG1235">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006533_2_4_1"/>
    <dbReference type="OMA" id="DVMTTMV"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF37">
        <property type="entry name" value="ABC1 FAMILY PROTEIN C10F6.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="4">
        <location>
            <begin position="196"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EAQ70945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA46419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="689" mass="78375" checksum="2BCCE303BB484A4C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH61</accession>
    <name>G5EH61_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g839</name>
        <name evidence="3" type="ORF">MGG_03045</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720637.1">
        <property type="nucleotide sequence ID" value="XM_003720589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH61"/>
    <dbReference type="SMR" id="G5EH61"/>
    <dbReference type="FunCoup" id="G5EH61">
        <property type="interactions" value="22"/>
    </dbReference>
    <dbReference type="GeneID" id="2682598"/>
    <dbReference type="KEGG" id="mgr:MGG_03045"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03045"/>
    <dbReference type="eggNOG" id="ENOG502S4CU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097653_0_2_1"/>
    <dbReference type="OMA" id="GFECDPL"/>
    <dbReference type="OrthoDB" id="9995210at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="215" mass="24065" checksum="39D5947E32A68A75" modified="2011-12-14" version="1">MAGDGEEHEGASVQERLIHACRTNDVGMLEQIVEEIGDEEKVAKVLNETKTVMGNHLLHEAALKGNYDAIDFLFSQDGLECDPINRAEGDTPVHSAIRWTSQQTDAEDRQLGAALVEMMLSDGASTRIRNKQRRTPLQLVEVVDKGNEALKDIIRRQEYEELNRGDFVDADSVAAPASRQQAREESSDDDAEFSGSDDEERAEWERRRKAKGKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHF5</accession>
    <name>G5EHF5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysR family regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g1121</name>
        <name evidence="2" type="ORF">MGG_10342</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720476.1">
        <property type="nucleotide sequence ID" value="XM_003720428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHF5"/>
    <dbReference type="SMR" id="G5EHF5"/>
    <dbReference type="GeneID" id="2681917"/>
    <dbReference type="KEGG" id="mgr:MGG_10342"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10342"/>
    <dbReference type="eggNOG" id="ENOG502S6KB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029797_2_1_1"/>
    <dbReference type="OMA" id="YCCRSIL"/>
    <dbReference type="OrthoDB" id="21502at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF294">
        <property type="entry name" value="ACETYLTRANSFERASE MATC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ71714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA45733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="57454" checksum="61637447B753CDFD" modified="2011-12-14" version="1">MGIFSSTRVPPPKVPTDTVIPLREMDSLPLSVGICNEFSFYFQDVLNVHKLQAALDRLVSKEKWRKMGARLRRNKDGKLEYHIPAEFSEKRPGVLHSQQTFATCIADHPVLSQIPKGRGEKPVLMHPSWHFRPHMRGPNSPRSYEDWLYADIPQLAVHFVVFKDATIFTLTYLHSFMDGSGLATLTRAWTAVLRGEDDSLPPFIGYEHADDPLATLHRQRPGSDYLLAPKALKGWGFFVFVVRQMLERLWWPQEEARVVCIPSAYIKRLADVARAQLDAAHRAKNDDGSGSKPFVGESDVLLAWWIMNVVRALKPAPSRTVALINAFDARPLLTEMGLLPRPEAAFFGNAAYGCITLSAARNYLRSTTEAPLTPLAASIRRDMLTQRTVEQVQAQLAALRESLATAGRPPLYGSSDMMFFAYSNLNTFKLYEADFSHALMSTEDEGAPKVNPEAYRRGTPTWISSTSTEAGFSPRNTGLFMGKDKAGYWWLFACLRKGAWKNIEEQLKAHL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-10-05" modified="2026-01-28" version="95" xmlns="https://uniprot.org/uniprot">
    <accession>A4R5F6</accession>
    <accession>G4NF47</accession>
    <name>ARGJ_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arginine biosynthesis bifunctional protein ArgJ, mitochondrial</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">Glutamate N-acetyltransferase</fullName>
                <shortName evidence="1">GAT</shortName>
                <ecNumber evidence="1">2.3.1.35</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">Ornithine acetyltransferase</fullName>
                <shortName evidence="1">OATase</shortName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="1">Ornithine transacetylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">Amino-acid acetyltransferase</fullName>
                <ecNumber evidence="1">2.3.1.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">N-acetylglutamate synthase</fullName>
                <shortName evidence="1">AGS</shortName>
            </alternativeName>
        </domain>
        <component>
            <recommendedName>
                <fullName evidence="1">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="1">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name type="ORF">MGG_04210</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">This protein may be expected to contain an N-terminal transit peptide but none has been predicted.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ArgJ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="1"/>
    <dbReference type="EC" id="2.3.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719608.1">
        <property type="nucleotide sequence ID" value="XM_003719560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R5F6"/>
    <dbReference type="SMR" id="A4R5F6"/>
    <dbReference type="FunCoup" id="A4R5F6">
        <property type="interactions" value="277"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4R5F6"/>
    <dbReference type="MEROPS" id="T05.001"/>
    <dbReference type="EnsemblFungi" id="MGG_04210T0">
        <property type="protein sequence ID" value="MGG_04210T0"/>
        <property type="gene ID" value="MGG_04210"/>
    </dbReference>
    <dbReference type="GeneID" id="2677436"/>
    <dbReference type="KEGG" id="mgr:MGG_04210"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04210"/>
    <dbReference type="eggNOG" id="KOG2786">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027172_1_0_1"/>
    <dbReference type="InParanoid" id="A4R5F6"/>
    <dbReference type="OMA" id="WGRIVMA"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00111"/>
    </dbReference>
    <dbReference type="PHI-base" id="PHI:5234"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:L-glutamate N-acetyltransferase activity, acting on acetyl-L-ornithine as donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006592">
        <property type="term" value="P:ornithine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.70.12:FF:000001">
        <property type="entry name" value="Arginine biosynthesis bifunctional protein ArgJ, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.340:FF:000002">
        <property type="entry name" value="Arginine biosynthesis bifunctional protein ArgJ, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2330.10:FF:000001">
        <property type="entry name" value="Arginine biosynthesis bifunctional protein ArgJ, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2330.10">
        <property type="entry name" value="arginine biosynthesis bifunctional protein suprefamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="entry name" value="ArgJ beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.70.12">
        <property type="entry name" value="L-amino peptidase D-ALA esterase/amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003802">
        <property type="entry name" value="PRK05388.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100:SF0">
        <property type="entry name" value="ARGININE BIOSYNTHESIS BIFUNCTIONAL PROTEIN ARGJ, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="DmpA/ArgJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0055">Arginine biosynthesis</keyword>
    <keyword id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000398062" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="1">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000398063" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="1">
        <location>
            <begin position="231"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="1">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="1">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="1">
        <location>
            <begin position="230"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03124"/>
        </source>
    </evidence>
    <sequence length="464" mass="48955" checksum="C451D7D625F5162A" modified="2012-01-25" version="2" precursor="true">MASKSTSTAVWGQLRHLAQQQTRCYSATADSIPASKKKYVPTKGVYPKGFRVSGTIVGVKPGNTTKPDLAFVTSDTPCAAAAVFTKNRFQAAPVTFSRDLLKKKGNSGVNGVIINSGCANAVTGKGGLEDAESMAREADRCLGGDGTIVMSTGVIGQRLPIKRILDNVPAAHSRLGSSHDHWLSCATAICTTDTFPKLMSRSFTLPSSPSVEYRIAGMTKGAGMIHPNMATLLGVIATDAPIAPAVLPSLLKNAVDRSFNSITIDGDTSTNDTVALLANGAAGGKEIASESSPDFAAFRDVLNVFSEDLAKLIVRDGEGATKFVTIRVVESDSEETAKKVASTIARSPLVKTALYGKDANWGRILCATGYALISEPGSAAVAEVSDKIVPEKTNVSFVPTDGTAELKLLVDGEPEQVDEVRAAEILKAEDLEILVRLGTGKAEGTYWTCDFSHEYVTINGDYRT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-08-21" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>A4RCX7</accession>
    <accession>G4NBX6</accession>
    <name>H3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">HHT1</name>
        <name type="ORF">MGG_01159</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text>Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text>The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">Phosphorylated to form H3S10ph. H3S10ph promotes subsequent H3K14ac formation and is required for transcriptional activation through TBP recruitment to the promoters.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Mono-, di- and trimethylated by the COMPASS complex to form H3K4me1/2/3. H3K4me activates gene expression by regulating transcription elongation and plays a role in telomere length maintenance. H3K4me enrichment correlates with transcription levels, and occurs in a 5' to 3' gradient with H3K4me3 enrichment at the 5'-end of genes, shifting to H3K4me2 and then H3K4me1. Methylated by SET2 to form H3K36me. H3K36me represses gene expression. Methylated by DOT1 to form H3K79me. H3K79me is required for association of SIR proteins with telomeric regions and for telomeric silencing. The COMPASS-mediated formation of H3K4me2/3 and the DOT1-mediated formation of H3K79me require H2BK123ub1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Acetylation of histone H3 leads to transcriptional activation. H3K14ac formation by GCN5 is promoted by H3S10ph. H3K14ac can also be formed by ESA1. H3K56ac formation occurs predominantly in newly synthesized H3 molecules during G1, S and G2/M of the cell cycle and may be involved in DNA repair.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">To ensure consistency between histone entries, we follow the 'Brno' nomenclature for histone modifications, with positions referring to those used in the literature for the 'closest' model organism. Due to slight variations in histone sequences between organisms and to the presence of initiator methionine in UniProtKB/Swiss-Prot sequences, the actual positions of modified amino acids in the sequence generally differ. In this entry the following conventions are used: H3K4me1/2/3 = mono-, di- and trimethylated Lys-5; H3K9ac = acetylated Lys-10; H3K9me1 = monomethylated Lys-10; H3S10ph = phosphorylated Ser-11; H3K14ac = acetylated Lys-15; H3K14me2 = dimethylated Lys-15; H3K18ac = acetylated Lys-19; H3K18me1 = monomethylated Lys-19; H3K23ac = acetylated Lys-24; H3K23me1 = monomethylated Lys-24; H3K27ac = acetylated Lys-28; H3K27me1/2/3 = mono-, di- and trimethylated Lys-28; H3K36ac = acetylated Lys-37; H3K36me1/2/3 = mono-, di- and trimethylated Lys-37; H3K56ac = acetylated Lys-57; H3K64ac = acetylated Lys-65; H3K79me1/2/3 = mono-, di- and trimethylated Lys-80.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717762.1">
        <property type="nucleotide sequence ID" value="XM_003717714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RCX7"/>
    <dbReference type="SMR" id="A4RCX7"/>
    <dbReference type="FunCoup" id="A4RCX7">
        <property type="interactions" value="824"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RCX7"/>
    <dbReference type="EnsemblFungi" id="MGG_01159T0">
        <property type="protein sequence ID" value="MGG_01159T0"/>
        <property type="gene ID" value="MGG_01159"/>
    </dbReference>
    <dbReference type="GeneID" id="2675178"/>
    <dbReference type="KEGG" id="mgr:MGG_01159"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01159"/>
    <dbReference type="eggNOG" id="KOG1745">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078295_4_0_1"/>
    <dbReference type="InParanoid" id="A4RCX7"/>
    <dbReference type="OMA" id="HIFAEMA"/>
    <dbReference type="OrthoDB" id="842664at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000010">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0007">Acetylation</keyword>
    <keyword id="KW-0158">Chromosome</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-0544">Nucleosome core</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="initiator methionine" description="Removed" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000297748" description="Histone H3">
        <location>
            <begin position="2"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6,N6,N6-trimethyllysine; alternate" evidence="1">
        <location>
            <position position="5"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6,N6-dimethyllysine; alternate" evidence="1">
        <location>
            <position position="5"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-methyllysine; alternate" evidence="1">
        <location>
            <position position="5"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine; alternate" evidence="1">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-methyllysine; alternate" evidence="1">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6,N6-dimethyllysine; alternate" evidence="1">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine; alternate" evidence="1">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine; alternate" evidence="1">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-methyllysine; alternate" evidence="1">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine; alternate" evidence="1">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-methyllysine; alternate" evidence="1">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6,N6,N6-trimethyllysine; alternate" evidence="1">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6,N6-dimethyllysine; alternate" evidence="1">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine; alternate" evidence="1">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-methyllysine; alternate" evidence="1">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6,N6,N6-trimethyllysine; alternate" evidence="1">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6,N6-dimethyllysine; alternate" evidence="1">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine; alternate" evidence="1">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-methyllysine; alternate" evidence="1">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6,N6,N6-trimethyllysine; alternate" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6,N6-dimethyllysine; alternate" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-methyllysine; alternate" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="136" mass="15392" checksum="9AF51E808E698349" modified="2007-05-15" version="1">MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKSDLRFQSSAIGALQESVESYLVSLFEDTNLCAIHAKRVTIQSKDIQLARRLRGERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLB6</accession>
    <name>G4MLB6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="16">Cytochrome P450</fullName>
                <ecNumber evidence="16">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="16">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MGG_05401</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 16">
            <text>an organic molecule + reduced [NADPH--hemoprotein reductase] + O2 = an alcohol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="16">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16 17">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="16"/>
    <dbReference type="EC" id="1.6.2.4" evidence="16"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710258.1">
        <property type="nucleotide sequence ID" value="XM_003710210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLB6"/>
    <dbReference type="SMR" id="G4MLB6"/>
    <dbReference type="STRING" id="242507.G4MLB6"/>
    <dbReference type="GeneID" id="2676046"/>
    <dbReference type="KEGG" id="mgr:MGG_05401"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05401"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_7_0_1"/>
    <dbReference type="InParanoid" id="G4MLB6"/>
    <dbReference type="OMA" id="CEFMAQR"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06206">
        <property type="entry name" value="bifunctional_CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11068">
        <property type="entry name" value="CYP120A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000040">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000198">
        <property type="entry name" value="Bifunctional cytochrome P450/NADPH--P450 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF127">
        <property type="entry name" value="BIFUNCTIONAL CYTOCHROME P450_NADPH--P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 16" id="KW-0274">FAD</keyword>
    <keyword evidence="5 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 16" id="KW-0288">FMN</keyword>
    <keyword evidence="4 16 17" id="KW-0349">Heme</keyword>
    <keyword evidence="12 16 17" id="KW-0408">Iron</keyword>
    <keyword evidence="7 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 16" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 16" id="KW-0521">NADP</keyword>
    <keyword evidence="11 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="19">
        <location>
            <begin position="544"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="20">
        <location>
            <begin position="718"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="17">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047827"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00049342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EHA57646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1116" mass="123626" checksum="14D8EC471CE74269" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLH9</accession>
    <name>G4MLH9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003711064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLH9"/>
    <dbReference type="SMR" id="G4MLH9"/>
    <dbReference type="GeneID" id="12986915"/>
    <dbReference type="KEGG" id="mgr:MGG_16548"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16548"/>
    <dbReference type="HOGENOM" id="CLU_2638529_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLH9"/>
    <dbReference type="OrthoDB" id="10388313at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA58500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="77" mass="8892" checksum="6F5B86D164A77DE9" modified="2011-12-14" version="1">MPATSLRLNMVGHYLRPGEGFGSQGTMNKTADLKRTRDNLKDYNLISEDFEEFLRSETLQKRSLLEHSLYKDTLITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLK0</accession>
    <name>G4MLK0_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">DNA polymerase delta subunit 4</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06731</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709445.1">
        <property type="nucleotide sequence ID" value="XM_003709397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLK0"/>
    <dbReference type="SMR" id="G4MLK0"/>
    <dbReference type="STRING" id="242507.G4MLK0"/>
    <dbReference type="GeneID" id="2684904"/>
    <dbReference type="KEGG" id="mgr:MGG_06731"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06731"/>
    <dbReference type="eggNOG" id="ENOG502SC9I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077732_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLK0"/>
    <dbReference type="OMA" id="HYGPCTG"/>
    <dbReference type="OrthoDB" id="337486at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007218">
        <property type="entry name" value="DNA_pol_delta_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04081">
        <property type="entry name" value="DNA_pol_delta_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="21358" checksum="692512D15129AA50" modified="2011-12-14" version="1">MPTTRRSASAQGAASKQSKLSFTHRVTKPVAPAGKKQLVSPPLVKELLSEKKVDPVPEIQLEQEEEFEIPAPVEVVKEKSEVEIRAEKITSAQINKYWEELEAQRLAPRVHQEDLDVGEKVLRYFDVSSQYGPCIGSSRKRRWMRAQRLGLNPPIEALAVLVHEEAAGQDEGSQRAYIDEIMNSTAIGVGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLU6</accession>
    <name>G4MLU6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_15181</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
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                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
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                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
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                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
        </source>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="30"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="4">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA56936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="297" mass="32708" checksum="EBAC3BF0AFB549DD" modified="2011-12-14" version="1">MTTASTLLAQKAKLATGQTIPRIQLGLYMMSRSEASRSVCWALEAGYRGFDCAQMYRNEAEAGAAIREAIDGSGGSSSSSSSSSSSKLTREDVFYTTKLASNSESYDAVRKSIRKSVDACGLGYVDLFLLHSPYGGREARLTSWRAVEDAIDAGEVKMGGVSNYGVQHIEELMASKPRHHPVINQIEVHPFNTQISIREACARHNIVIEAYAPLARAMRMRDPTMVSLSKKYGCTVAQLFVKWSLQQGFVTLPKSSKRERIVENVDVGGFEISQEDMEKMNGLDEKLVTDWDPTDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNB6</accession>
    <name>G4MNB6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Knr4/Smi1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_02081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708851.1">
        <property type="nucleotide sequence ID" value="XM_003708803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNB6"/>
    <dbReference type="SMR" id="G4MNB6"/>
    <dbReference type="GeneID" id="2681236"/>
    <dbReference type="KEGG" id="mgr:MGG_02081"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02081"/>
    <dbReference type="eggNOG" id="ENOG502R41D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_427582_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNB6"/>
    <dbReference type="OMA" id="KIAMWWR"/>
    <dbReference type="OrthoDB" id="2788868at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="561" mass="63368" checksum="3F48359757E8EACB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNN3</accession>
    <name>G4MNN3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710551.1">
        <property type="nucleotide sequence ID" value="XM_003710503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNN3"/>
    <dbReference type="SMR" id="G4MNN3"/>
    <dbReference type="GeneID" id="2676014"/>
    <dbReference type="KEGG" id="mgr:MGG_05658"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05658"/>
    <dbReference type="eggNOG" id="ENOG502S764">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107661_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNN3"/>
    <dbReference type="OMA" id="YRRYQGN"/>
    <dbReference type="OrthoDB" id="2555434at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646:SF1">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38646">
        <property type="entry name" value="YALI0F00814P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="17937" checksum="AD7DDEB838ECC208" modified="2011-12-14" version="1">MLRAFDPHAEDKLHLRLHRARSVVLTSEELVEIRAAQRTYEGAYMRTALSQFSFALIILKIFTSEFYPIGALFAVYGFCVLLVAVYRRHEGNRQFFNEEVSDSDTSPARHGVGGRGDHEMQPLTKRKFRTSGNSVALLAALSLGAYITLLWLIWNMEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP94</accession>
    <name>G4MP94_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708965.1">
        <property type="nucleotide sequence ID" value="XM_003708917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP94"/>
    <dbReference type="GeneID" id="2681060"/>
    <dbReference type="KEGG" id="mgr:MGG_02202"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02202"/>
    <dbReference type="HOGENOM" id="CLU_1299933_0_0_1"/>
    <dbReference type="InParanoid" id="G4MP94"/>
    <dbReference type="OMA" id="MPAVIHK"/>
    <dbReference type="OrthoDB" id="10499359at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465330" evidence="1">
        <location>
            <begin position="18"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="212" mass="23660" checksum="97D6508468A222D5" modified="2011-12-14" version="1">MRFGNFLFFYTFCGALALPPPVSNPQTVSNPAPVSNTPYVPRGGLLAQTDVVRTPQDFQSCVNTILVLGHSSIDMTGDEWLKSRMKAELLKAAQEECREEFPDTAPPTSSMRYPDVKALMPAVIHKPKDFESCVRNVRVLMSSSTKLVPRHLRAHYKQVLEHVIRRDCPSPGRAANATDGERQFRHGMVSWQQASCSLCGVDQLGSNRTERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPT5</accession>
    <name>G4MPT5_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709844.1">
        <property type="nucleotide sequence ID" value="XM_003709796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPT5"/>
    <dbReference type="STRING" id="242507.G4MPT5"/>
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    <dbReference type="KEGG" id="mgr:MGG_09224"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09224"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_138_0_1"/>
    <dbReference type="InParanoid" id="G4MPT5"/>
    <dbReference type="OMA" id="NIWSTER"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10622:SF10">
        <property type="entry name" value="HET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26640">
        <property type="entry name" value="DUF8212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="21"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8212" evidence="2">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="670" mass="76231" checksum="9D2B529C3AC32A83" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQZ9</accession>
    <name>G4MQZ9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hormone-sensitive lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709146.1">
        <property type="nucleotide sequence ID" value="XM_003709098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQZ9"/>
    <dbReference type="SMR" id="G4MQZ9"/>
    <dbReference type="STRING" id="242507.G4MQZ9"/>
    <dbReference type="GeneID" id="2681473"/>
    <dbReference type="KEGG" id="mgr:MGG_02376"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02376"/>
    <dbReference type="eggNOG" id="KOG4388">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003590_1_0_1"/>
    <dbReference type="InParanoid" id="G4MQZ9"/>
    <dbReference type="OMA" id="NMYDATY"/>
    <dbReference type="OrthoDB" id="5570009at2759"/>
    <dbReference type="PHI-base" id="PHI:2025"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004771">
        <property type="term" value="F:sterol ester esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025:SF3">
        <property type="entry name" value="HORMONE-SENSITIVE LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="220"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="478"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="630"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="654"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="688"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="709"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR59</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16290</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710003.1">
        <property type="nucleotide sequence ID" value="XM_003709955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR59"/>
    <dbReference type="GeneID" id="12985314"/>
    <dbReference type="KEGG" id="mgr:MGG_16290"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16290"/>
    <dbReference type="HOGENOM" id="CLU_2455159_0_0_1"/>
    <dbReference type="InParanoid" id="G4MR59"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="89" mass="9785" checksum="C81706A25393B261" modified="2011-12-14" version="1">MGWMVDPEGGDVLVASWSTFQQVRGASAWKRADIRSPDGMLEPRDGTIKLQSVPWIPGRENGVSPVRSECIRIASSFEFMLHSLVAEGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR60</accession>
    <name>G4MR60_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_09907</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Deubiquitinates the creA catabolic repressor and the quinate permease qutD. Also plays a role in response to carbon starvation and the control of extracellular proteases activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with creA, creC and qutD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase C19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710004.1">
        <property type="nucleotide sequence ID" value="XM_003709956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR60"/>
    <dbReference type="SMR" id="G4MR60"/>
    <dbReference type="FunCoup" id="G4MR60">
        <property type="interactions" value="399"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MR60"/>
    <dbReference type="MEROPS" id="C19.008"/>
    <dbReference type="GeneID" id="2680877"/>
    <dbReference type="KEGG" id="mgr:MGG_09907"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09907"/>
    <dbReference type="eggNOG" id="KOG1864">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008279_0_2_1"/>
    <dbReference type="InParanoid" id="G4MR60"/>
    <dbReference type="OMA" id="PVLQMDY"/>
    <dbReference type="OrthoDB" id="27652at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02663">
        <property type="entry name" value="Peptidase_C19G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000075">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase creB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF733">
        <property type="entry name" value="RE52890P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="59"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="91"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="518"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="558"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="560"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="602"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="708"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="719"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="736"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="748"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA57392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="766" mass="84780" checksum="0A3734704FE8D3D9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR90</accession>
    <name>G4MR90_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Meiotic recombination protein DMC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710827.1">
        <property type="nucleotide sequence ID" value="XM_003710779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR90"/>
    <dbReference type="GeneID" id="5048994"/>
    <dbReference type="KEGG" id="mgr:MGG_13774"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13774"/>
    <dbReference type="eggNOG" id="ENOG502QZN7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062681_0_0_1"/>
    <dbReference type="InParanoid" id="G4MR90"/>
    <dbReference type="OMA" id="TTDMVRC"/>
    <dbReference type="OrthoDB" id="5420410at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031349">
        <property type="entry name" value="Tfb6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37781:SF1">
        <property type="entry name" value="ADR380WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37781">
        <property type="entry name" value="TFIIH COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17110">
        <property type="entry name" value="TFB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="37315" checksum="E13E2FA7545105CC" modified="2011-12-14" version="1">MADDTQFQTIFKQEEEPQSITFDFTQDPQEQKSLTFDFSEDSHQTAIKEESRTEPERQQQSGPSQAAPPPQQPPQNPSRPGGFFPPSTTLPSPAPSNQSRLPLDLPHPRATALRPGSVKEDNLRRFVERRIMHINRRYVKKFGIPDPGDEVAGYQSISELCRDLDSVINMLWLSGTPGIQIPYFLNISHELTTWIDSFPPSPAAMLGTLARLDHCLASLIAGRDIQTDEDLPGFVVLPGGTGARLGGMSRTDMVRCRSIVEQTRLLVVDVMSRNPEAEGMDIVEDVTETEAETTDGEGRSARFGGYGDDEDDAIHLAAAKVYENTLIQLGATLGQGPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSL0</accession>
    <name>G4MSL0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714433.1">
        <property type="nucleotide sequence ID" value="XM_003714385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSL0"/>
    <dbReference type="GeneID" id="12984660"/>
    <dbReference type="KEGG" id="mgr:MGG_15706"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15706"/>
    <dbReference type="HOGENOM" id="CLU_2027178_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSL0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="122" mass="12644" checksum="9B30580488EDC4ED" modified="2011-12-14" version="1">MAMAIGCFFTWEMVTYLLRRLPRLPEFLGRQSSGDAAHRSGKTRPTSPTRSIDRTLLLLMLLGFRLGVCADAGPVADAAAASSPKGTTARQNPQEGRGAGKAGQNGPCGPPASAGDTGTGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSW4</accession>
    <name>G4MSW4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytoplasmic tRNA 2-thiolation protein 1</fullName>
            <ecNumber evidence="6">2.7.7.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cytoplasmic tRNA adenylyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NCS6</name>
        <name evidence="6" type="synonym">CTU1</name>
        <name evidence="11" type="ORF">MGG_04613</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="6"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713625.1">
        <property type="nucleotide sequence ID" value="XM_003713577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSW4"/>
    <dbReference type="SMR" id="G4MSW4"/>
    <dbReference type="FunCoup" id="G4MSW4">
        <property type="interactions" value="455"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSW4"/>
    <dbReference type="GeneID" id="2677999"/>
    <dbReference type="KEGG" id="mgr:MGG_04613"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04613"/>
    <dbReference type="eggNOG" id="KOG2840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026481_1_3_1"/>
    <dbReference type="InParanoid" id="G4MSW4"/>
    <dbReference type="OMA" id="KPVRGIC"/>
    <dbReference type="OrthoDB" id="198857at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002144">
        <property type="term" value="C:cytosolic tRNA wobble base thiouridylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="CTU1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000132">
        <property type="entry name" value="Cytoplasmic tRNA 2-thiolation protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03053">
        <property type="entry name" value="CTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056369">
        <property type="entry name" value="CTU1-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032442">
        <property type="entry name" value="CTU1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000541">
        <property type="entry name" value="Ncs6/Tuc1/Ctu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035107">
        <property type="entry name" value="tRNA_thiolation_TtcA_Ctu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020554">
        <property type="entry name" value="UPF0021_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807">
        <property type="entry name" value="ATPASES OF THE PP SUPERFAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807:SF12">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16503">
        <property type="entry name" value="zn-ribbon_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004976">
        <property type="entry name" value="ATPase_YdaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01263">
        <property type="entry name" value="UPF0021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="9">
        <location>
            <begin position="54"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Cytoplasmic tRNA 2-thiolation protein 1 C-terminal" evidence="10">
        <location>
            <begin position="376"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR004976-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA53818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="412" mass="45032" checksum="B54E0946B6C73C82" modified="2011-12-14" version="1">MAPALCVLCGTERALIKRPKNHHKLCKKCFIQIFEDEVHHTITSSNLFTPGERVAIGASGGKDSTVLASVLKTLNERYKYGLELVLLSVDEGIKGYRDDSLETVKRNAVQYDMPLKIVGYDELYGWTMDQVVETVGKKGNCTYCGIFRRQALDRGAKVLDIKHVVTGHNADDVAETVLMNLLRGDLARLSRSTNIMTGANSALSDNVKRSKPLKYAYEKEIVLYAHHKKLDYFSTECLYSPEAFRGSARSLIKNLEKVRPSAILDIVRSGEDMARLVPSEISGSSCACNGEGEATQEYPEGEPGGCGSANGRSSGGEMAEMEARLRKNQDSAALEVDVGALENQKKDADAQRTMRVPIRNAPAKGKGGTVTRQVLGTCIRCGYMSSQAICQACTLLDGLNKNRPQIQVGDTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT37</accession>
    <name>G4MT37_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein kinase RIO2</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Serine/threonine-protein kinase rio2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_07119</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715309.1">
        <property type="nucleotide sequence ID" value="XM_003715261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT37"/>
    <dbReference type="SMR" id="G4MT37"/>
    <dbReference type="FunCoup" id="G4MT37">
        <property type="interactions" value="1231"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MT37"/>
    <dbReference type="GeneID" id="2683241"/>
    <dbReference type="KEGG" id="mgr:MGG_07119"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07119"/>
    <dbReference type="eggNOG" id="KOG2268">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018693_0_0_1"/>
    <dbReference type="InParanoid" id="G4MT37"/>
    <dbReference type="OMA" id="GYTNFRE"/>
    <dbReference type="OrthoDB" id="10258631at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05144">
        <property type="entry name" value="RIO2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000053">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000566">
        <property type="entry name" value="Serine/threonine-protein kinase rio2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000052">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030484">
        <property type="entry name" value="Rio2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852">
        <property type="entry name" value="SER/THR-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="16">
        <location>
            <begin position="67"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="354"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00068353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00068837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA55502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="422" mass="46667" checksum="C5C060367A553E60" modified="2011-12-14" version="1">MKLDSKAMRHLTSEDWKVLTGVEQGSKNHEIVPTPLIEKLSRLRGGASGVHRSISNLAKVGLIARVKEAKYDGYRLTYGGLDYLALHTHSTKKAIYSVGTRIGVGKESDIMIVADDTGCQRVLKIHRLGRISFRTVKANRDYLKKRGQASGSWMYLSRLAAMKEFAFMQALREEGFPVPEPLSQSRHTIVMSLIDAYPLRQISSVPNPAALYAELMLLILRLAKHGLIHGDFNEFNILLKEEKDKKNHASSTESAENGSSEVGAALPTPILIDFPQMVSMDHPNAEMYFDRDVACIKRFFERRFHFSSDEPGPFYKDALKTVGADGARRLDATVEASGFTKKMSKDLEKAIQEEAASRREQTNDIDGEFEGSDAEQDSDAEAESEQADLNGSGQTEHDASDSKLPLTGIEAAVQGTKISDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUF8</accession>
    <name>G4MUF8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">poly(A)-specific ribonuclease</fullName>
            <ecNumber evidence="5">3.1.13.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_01666</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CAF1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="5"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714652.1">
        <property type="nucleotide sequence ID" value="XM_003714604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUF8"/>
    <dbReference type="SMR" id="G4MUF8"/>
    <dbReference type="STRING" id="242507.G4MUF8"/>
    <dbReference type="GeneID" id="2679608"/>
    <dbReference type="KEGG" id="mgr:MGG_01666"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01666"/>
    <dbReference type="eggNOG" id="KOG0304">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027974_3_0_1"/>
    <dbReference type="InParanoid" id="G4MUF8"/>
    <dbReference type="OMA" id="QMRDRIF"/>
    <dbReference type="OrthoDB" id="1164111at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039637">
        <property type="entry name" value="CNOT7/CNOT8/Pop2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10797">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="420"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="431"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="466"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA54845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="521" mass="56726" checksum="CD079D439032AC81" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUH0</accession>
    <name>G4MUH0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715469.1">
        <property type="nucleotide sequence ID" value="XM_003715421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUH0"/>
    <dbReference type="STRING" id="242507.G4MUH0"/>
    <dbReference type="GeneID" id="2682995"/>
    <dbReference type="KEGG" id="mgr:MGG_07249"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07249"/>
    <dbReference type="eggNOG" id="KOG1840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_774041_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUH0"/>
    <dbReference type="OMA" id="EAFESDH"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053137">
        <property type="entry name" value="NLR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082:SF6">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46082">
        <property type="entry name" value="ATP/GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="38752" checksum="1CE719879CDAA672" modified="2011-12-14" version="1">MDEECVAIEGKTLYNSGSFSIDKATPDTWGRSIVNGGRPTTGPRVRGHGQGRDGEPDGLMSSYTALRLVVLAGICAGVPSQEKENDILLGDVVISETVIQYDFGRQYPGEFSTKVSIADGLGRADASIRTQVEAFESDHERDRLINRAANVLTEIHDKGKKKRRPVDYSCPHPSTDLLFEFSYLHRHQGSSDCGCSTTQACNVAVATACEELNCGASYFVHRPRLERLVSNQDDAAFAELEIFVGCIGSGDTVMKSGERRDKMAKKHGIIAFEIEGAGAWDGAPCVVVKGGGKAVAHSRMQRSPALVLASLSLQPQQLVRLFLIRQEQFNEARIAVTRCCLSSVVQPKAASTTNMVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUL2</accession>
    <name>G4MUL2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SCY1 protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_07285</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715511.1">
        <property type="nucleotide sequence ID" value="XM_003715463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUL2"/>
    <dbReference type="SMR" id="G4MUL2"/>
    <dbReference type="FunCoup" id="G4MUL2">
        <property type="interactions" value="1099"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUL2"/>
    <dbReference type="GeneID" id="2683031"/>
    <dbReference type="KEGG" id="mgr:MGG_07285"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07285"/>
    <dbReference type="eggNOG" id="KOG1243">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010392_1_2_1"/>
    <dbReference type="InParanoid" id="G4MUL2"/>
    <dbReference type="OMA" id="NDTSWAG"/>
    <dbReference type="OrthoDB" id="447103at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF3">
        <property type="entry name" value="N-TERMINAL KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="544"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="596"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="606"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="670"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="688"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="711"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="786"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="796"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA55704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="806" mass="86863" checksum="77A38560C974113A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUT7</accession>
    <name>G4MUT7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_14810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714674.1">
        <property type="nucleotide sequence ID" value="XM_003714626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUT7"/>
    <dbReference type="GeneID" id="5049041"/>
    <dbReference type="KEGG" id="mgr:MGG_14810"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14810"/>
    <dbReference type="HOGENOM" id="CLU_2278017_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUT7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="102" mass="11658" checksum="633897500D4B2996" modified="2011-12-14" version="1">MGWEQKFDGVNKRPAELPSQLSQVLAQKLRWKNGANCRWNFQLLLCWRQKTDLSFAGSPWATSLTQGRSPRLISGICRVCFLCSPWRRRVAPSSSPVGIEYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUZ7</accession>
    <name>G4MUZ7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715538.1">
        <property type="nucleotide sequence ID" value="XM_003715490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUZ7"/>
    <dbReference type="GeneID" id="12986699"/>
    <dbReference type="KEGG" id="mgr:MGG_15900"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15900"/>
    <dbReference type="HOGENOM" id="CLU_3087709_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUZ7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="52" mass="5603" checksum="E89F2B918959F83C" modified="2011-12-14" version="1">MDGGRRLTPHVPGMAWEWQGMNLLVVSMQDVLIRGFAVGGTHTTIVLSGTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV19</accession>
    <name>G4MV19_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715560.1">
        <property type="nucleotide sequence ID" value="XM_003715512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV19"/>
    <dbReference type="SMR" id="G4MV19"/>
    <dbReference type="STRING" id="242507.G4MV19"/>
    <dbReference type="GeneID" id="2683221"/>
    <dbReference type="KEGG" id="mgr:MGG_07325"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07325"/>
    <dbReference type="eggNOG" id="ENOG502S4JN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095059_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV19"/>
    <dbReference type="OMA" id="PHNDGEE"/>
    <dbReference type="OrthoDB" id="5344687at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42089">
        <property type="entry name" value="YALI0F09427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42089:SF1">
        <property type="entry name" value="YALI0F09427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="177" mass="19155" checksum="CFE14EE784816575" modified="2011-12-14" version="1">MNSRSHPLLEQVPLTVSPFIKLPQATTLPYTYRAMPSSLPPSSTGGNPSADDHQQQTDKPRYVVSGTGHAAHPDDIVASCRALQAHVAKLQADAEAELRELEERIRARELAEKRRVAPGWLDSEARILEPERKLADGMEGLSLRPGPGPGQEDGPSEMAAPDHDDPGAELDRVFGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVG5</accession>
    <name>G4MVG5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Serin endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_07358</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715598.1">
        <property type="nucleotide sequence ID" value="XM_003715550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVG5"/>
    <dbReference type="SMR" id="G4MVG5"/>
    <dbReference type="GeneID" id="2683077"/>
    <dbReference type="KEGG" id="mgr:MGG_07358"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07358"/>
    <dbReference type="eggNOG" id="KOG4266">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003559_3_1_1"/>
    <dbReference type="InParanoid" id="G4MVG5"/>
    <dbReference type="OMA" id="WPVYAYD"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02124">
        <property type="entry name" value="PA_PoS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="142"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="11">
        <location>
            <begin position="368"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="12">
        <location>
            <begin position="605"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA55791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="898" mass="95650" checksum="897DDB5A8B3EE784" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWG0</accession>
    <name>G4MWG0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">nicotinamidase</fullName>
            <ecNumber evidence="6">3.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Nicotinamide deamidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_08976</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; nicotinate biosynthesis; nicotinate from nicotinamide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.19" evidence="6"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714015.1">
        <property type="nucleotide sequence ID" value="XM_003713967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWG0"/>
    <dbReference type="SMR" id="G4MWG0"/>
    <dbReference type="FunCoup" id="G4MWG0">
        <property type="interactions" value="420"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MWG0"/>
    <dbReference type="GeneID" id="2679961"/>
    <dbReference type="KEGG" id="mgr:MGG_08976"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08976"/>
    <dbReference type="eggNOG" id="KOG4003">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_13_0_1"/>
    <dbReference type="InParanoid" id="G4MWG0"/>
    <dbReference type="OMA" id="DFVDSWP"/>
    <dbReference type="OrthoDB" id="3341310at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019363">
        <property type="term" value="P:pyridine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01011">
        <property type="entry name" value="nicotinamidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052347">
        <property type="entry name" value="Isochorismatase_Nicotinamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080:SF2">
        <property type="entry name" value="LD05707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080">
        <property type="entry name" value="PYRAZINAMIDASE/NICOTINAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="8">
        <location>
            <begin position="11"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA54208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="230" mass="24822" checksum="8E40FD27196EC426" modified="2011-12-14" version="1">MTTATDTFTPALIVVDLQEDFCPPNGSLAVPDGRAVAPVINKLLTSTAFVTRVATKDWHPQSHVSFAANHVSKEPFIDFVTITNPLNGSESYETRLWPVHCVQDTPGAALIPELDLGRIDEVLEKGIRSDVEMYSAFYPPLKDPRVGDSGLAGLLREKGISHVYVVGLAADYCVRSTALDAAAEGFVTVIVEEGTKPVDPAAWPTVRQEIIASGVGIVDMDSEEVKKLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY84</accession>
    <name>G4MY84_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714222.1">
        <property type="nucleotide sequence ID" value="XM_003714174.1"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
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            <dbReference type="PubMed" id="15846337"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
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                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
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                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
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            <fullName evidence="8">LITAF domain-containing protein</fullName>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Read N.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="MacDonald P.J.P."/>
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                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="PANTHER" id="PTHR23292:SF6">
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        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR23292">
        <property type="entry name" value="LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10601">
        <property type="entry name" value="zf-LITAF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00714">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51837">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="LITAF" evidence="8">
        <location>
            <begin position="45"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="161"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA53666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="208" mass="22407" checksum="E84B3059C6AA0FAF" modified="2011-12-14" version="1">MSAQPQDQINQAPAQPQAAYQTKAEQFQQSQQQQQQYGPAAQHHHQHVGATPLQSLGPAPAVVDCPFCQQRVMTRVNEEHSSMTYLLGVLIGCICICAACVPCLAHMCQDVTHFCTNCNQRVAHIPYSGGVQVIQPQPHQGANGQYNMGPQAVYGSENSKGAGVAPAAQQQQAAPAQQNQTQPAQQQGQDHIQPAPQPDAQPPQYSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZB6</accession>
    <name>G4MZB6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713478.1">
        <property type="nucleotide sequence ID" value="XM_003713430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZB6"/>
    <dbReference type="GeneID" id="12987085"/>
    <dbReference type="KEGG" id="mgr:MGG_15530"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15530"/>
    <dbReference type="HOGENOM" id="CLU_2015724_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZB6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="123" mass="13704" checksum="B8B1115232788974" modified="2011-12-14" version="1">MVWFDQTTKTKKKKMTDASNDACSSGAVRSTASVSRLGLFQGVPEEADKAGCKVELAQNYRYYGPIIGIYAVSKTKPCGPSLDGSRCLTQVTRRPRRRRQPLVSGTFFFRCRLLPLFVNQPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0S9</accession>
    <name>G4N0S9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711319.1">
        <property type="nucleotide sequence ID" value="XM_003711271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0S9"/>
    <dbReference type="GeneID" id="12987024"/>
    <dbReference type="KEGG" id="mgr:MGG_16628"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16628"/>
    <dbReference type="HOGENOM" id="CLU_2705293_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0S9"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="73" mass="8050" checksum="A8E6042D3BC2804D" modified="2011-12-14" version="1">MAHVSACACASAVRHCVGEKSSRIFVDKDTVVGGEYFTRVFDLSGEDPGKRANFNAVMRGLDPEMRNIRRFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0T4</accession>
    <name>G4N0T4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_07434</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711324.1">
        <property type="nucleotide sequence ID" value="XM_003711276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0T4"/>
    <dbReference type="FunCoup" id="G4N0T4">
        <property type="interactions" value="953"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N0T4"/>
    <dbReference type="GeneID" id="2683354"/>
    <dbReference type="KEGG" id="mgr:MGG_07434"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07434"/>
    <dbReference type="eggNOG" id="KOG1278">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010714_4_1_1"/>
    <dbReference type="InParanoid" id="G4N0T4"/>
    <dbReference type="OMA" id="KVYYMFG"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF111">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007361711" description="Transmembrane 9 superfamily member" evidence="7">
        <location>
            <begin position="27"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="549"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="587"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="618"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA51517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="657" mass="73336" checksum="47DDB8BB91169103" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1D2</accession>
    <name>G4N1D2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidase</fullName>
            <ecNumber evidence="2">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_09530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="2"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712210.1">
        <property type="nucleotide sequence ID" value="XM_003712162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1D2"/>
    <dbReference type="SMR" id="G4N1D2"/>
    <dbReference type="STRING" id="242507.G4N1D2"/>
    <dbReference type="GeneID" id="2680485"/>
    <dbReference type="KEGG" id="mgr:MGG_09530"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09530"/>
    <dbReference type="eggNOG" id="KOG4127">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031404_4_0_1"/>
    <dbReference type="InParanoid" id="G4N1D2"/>
    <dbReference type="OMA" id="CDHPRNI"/>
    <dbReference type="OrthoDB" id="445695at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01301">
        <property type="entry name" value="rDP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA52403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="461" mass="50949" checksum="D21BEEB16784F411" modified="2011-12-14" version="1">MASKQPSSRAFPISPSPGQAPARTRNGHVFVGFLTGLLALAFLFNPFWQHSYSCRAPWSARPTWSLPIEDRVEQILSQTPLIDGHNDLAILIRVLLHNHINTERFREEFETGTFFYHVDLARLRAGKNGGAFWSVFVPCPDNGTDFSDNNYSQSIRDTLQQIDVITRLTAAYPKDFSSVHINSSGAMAAFRENKLISPLGVEGLHQIGNSVANLRQYQSLGVRYATLTHNCHNRYADAAVLENPLRKAEPLWHGVSREGRRLVREMNRLGMIVDLSHVSEETMVDVLGGKHGWEGSLAPIIFSHSSAYALCPHPRNVKDHVLQLVKDRNSVVMVNFSADFVSCVDVGAENGLPGPDPNHEASLDRVVEHILHIGELIGFDHVGIGSDFDGIENTPKGLEDVSKFPDLVAELLKRGVSDEDTAKIVGGNVLRVWKAVDAVALQMQATGELPMEDELPGLTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1P7</accession>
    <name>G4N1P7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711426.1">
        <property type="nucleotide sequence ID" value="XM_003711378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1P7"/>
    <dbReference type="GeneID" id="12987052"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="82"/>
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    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA51619.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="113" mass="12780" checksum="8E9D41F5B803A68A" modified="2011-12-14" version="1">MINESQFEGSYFVQYIRSIWPVGSVLAGIRKIEPKSRERFAVAETGEVHLVSRLAETRRDICGTGKRSSKRGHNDSNWQNELELRNSAHPRLNRRCNTASHPSLHGIPTVGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1R3</accession>
    <name>G4N1R3_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
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    </protein>
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        <name evidence="3" type="ORF">MGG_09507</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA52428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_09507"/>
    <dbReference type="eggNOG" id="ENOG502QRPI">
        <property type="taxonomic scope" value="Eukaryota"/>
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        <property type="component" value="Chromosome 3"/>
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        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
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        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46100">
        <property type="entry name" value="IMP2'P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46100:SF4">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="683"/>
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        </location>
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        </location>
    </feature>
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        <source>
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    </evidence>
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            <dbReference type="Pfam" id="PF00582"/>
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    </evidence>
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            <dbReference type="EMBL" id="EHA52428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="717" mass="77037" checksum="C6E9359297938545" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2C4</accession>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="67"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="132" mass="14465" checksum="538E0759AFB497F5" modified="2011-12-14" version="1">MSTNLPPGSATPSNSIPDNNTITMLGAAIAGIRGSLLRQMDNARGELDRCEAILATLVAFRAQAIDVKQKDAKLAEVEKEAARLQKKNALLKDEVKHLLTERDQLLDELELLKRERSGTDLQPEFTTGVLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N386</accession>
    <name>G4N386_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_10856</name>
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    <organism evidence="2 3">
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            <taxon>Sordariomycetes</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713238.1">
        <property type="nucleotide sequence ID" value="XM_003713190.1"/>
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    <dbReference type="KEGG" id="mgr:MGG_10856"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10856"/>
    <dbReference type="eggNOG" id="ENOG502SYT3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_169797_0_1_1"/>
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    <dbReference type="OMA" id="TGNKVDP"/>
    <dbReference type="OrthoDB" id="3050608at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="73" mass="7692" checksum="17A40B16A822EA73" modified="2011-12-14" version="1">MNSLTNNNGTAAPGQQNAGMAGEKRDYGDKAFDALAKKSGHPVDRNTSEKITDAARGAFEKVTGKKVNPKISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3V0</accession>
    <name>G4N3V0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-carbamoyl-L-amino acid hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05024</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712530.1">
        <property type="nucleotide sequence ID" value="XM_003712482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3V0"/>
    <dbReference type="SMR" id="G4N3V0"/>
    <dbReference type="STRING" id="242507.G4N3V0"/>
    <dbReference type="GeneID" id="2675706"/>
    <dbReference type="KEGG" id="mgr:MGG_05024"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05024"/>
    <dbReference type="eggNOG" id="ENOG502QPR4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024588_2_0_1"/>
    <dbReference type="InParanoid" id="G4N3V0"/>
    <dbReference type="OMA" id="IWPHGRW"/>
    <dbReference type="OrthoDB" id="4676at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03884">
        <property type="entry name" value="M20_bAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494:SF5">
        <property type="entry name" value="ALLANTOATE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="ALLANTOATE DEIMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="288"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="519" mass="56817" checksum="E5ECA49E782531C2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3V6</accession>
    <name>G4N3V6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712536.1">
        <property type="nucleotide sequence ID" value="XM_003712488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3V6"/>
    <dbReference type="GeneID" id="12985071"/>
    <dbReference type="KEGG" id="mgr:MGG_16844"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16844"/>
    <dbReference type="HOGENOM" id="CLU_2942226_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3V6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="60" mass="6931" checksum="E0998E123A199A3B" modified="2011-12-14" version="1">MATSRSTEKASMRLQNFTEAKSRAKSTKYVDWQDRPTSNNKFLIVSSFWGHKNNPSPRPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N434</accession>
    <name>G4N434_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16852</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000422">
        <property type="entry name" value="N-terminal-AcTrfase-A_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="596"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="606"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="632"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA52876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="837" mass="94388" checksum="BF8C153D2382F2D5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4Z4</accession>
    <name>G4N4Z4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_13226</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711913.1">
        <property type="nucleotide sequence ID" value="XM_003711865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4Z4"/>
    <dbReference type="STRING" id="242507.G4N4Z4"/>
    <dbReference type="GeneID" id="2683914"/>
    <dbReference type="KEGG" id="mgr:MGG_13226"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13226"/>
    <dbReference type="eggNOG" id="KOG2980">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055068_7_2_1"/>
    <dbReference type="InParanoid" id="G4N4Z4"/>
    <dbReference type="OMA" id="VFLAWQY"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF14">
        <property type="entry name" value="PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="9">
        <location>
            <begin position="147"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="324" mass="36111" checksum="DE628774E95913B2" modified="2011-12-14" version="1">MNCLGSSGRKMMCYSYSLAQHRNRVMLTAFRRPSSAFSTATTVMQRVPSRSQARLRPPQKPLASGAPVQETRQLVMANIVPNQPRGYIRPSRFTYRLILWGVFVGPCLVVFYWWASATVKASKNDDISQLKWMLENFTLSRKNIEEGRWWTLITSAFSHKDPFHLLFNMLSLRFGVEAALHTGLGPLRVLLLATGAALSSSYASLWDGATRKHGADRAGLGASGIVQGFLAAMALTRPWMQVSLMFIPIPVSLPIVWGLFTAWDFYNLHIARQNGDSPSASGSVVGYAAHLGGSAFGALYWFVRLRPVFGGMTLEYIRLVIFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N601</accession>
    <name>G4N601_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">6-phosphogluconolactonase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716896.1">
        <property type="nucleotide sequence ID" value="XM_003716848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N601"/>
    <dbReference type="SMR" id="G4N601"/>
    <dbReference type="GeneID" id="2684786"/>
    <dbReference type="KEGG" id="mgr:MGG_06631"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06631"/>
    <dbReference type="eggNOG" id="ENOG502QRFW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038716_0_1_1"/>
    <dbReference type="InParanoid" id="G4N601"/>
    <dbReference type="OMA" id="RFTIAEC"/>
    <dbReference type="OrthoDB" id="9972196at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466637" description="6-phosphogluconolactonase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="45041" checksum="E855A679F3AF3FB6" modified="2011-12-14" version="1">MLPTSLYLLLSAAVGGAVAGPVYTRQANATAAKQKVIIGGGSINKISIAQFDGAKFNILKSAALPVQGAPTWLAFKEPNFLYSVNENGVELSLFTVDTKTNDIKFVKSVNGSAGVVHLEFNKDKTRMVGASFGKGTIDVWKLAADGTPELLGKPIATNSTGATLGPNKARQEAPHAHQSVLDNSGRFFFVNDLGLDTITIVDSKDDKFKIADSIKVSPGCGPRHGAFYPATGDATHYLLVCEMLNTVIVNKLNYTGNAGNKDKEGVPTVQPIQLISTFGEKNPPNPKAVPGAGEIAVAADGKSVYVSNRLSFDPDLKQKGRDSIAQFKATLAGEAKNLVLSFDNSVDSQGAVPRMFSLSADKDQAVLFGTNQNAGNGIAAFERSKDSGKLSLIKGSEIDYAVFATDANKDKPGFGPQFIAGIPSTVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6A6</accession>
    <name>G4N6A6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable quinone oxidoreductase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">NADPH:quinone reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_06586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716947.1">
        <property type="nucleotide sequence ID" value="XM_003716899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6A6"/>
    <dbReference type="SMR" id="G4N6A6"/>
    <dbReference type="FunCoup" id="G4N6A6">
        <property type="interactions" value="636"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N6A6"/>
    <dbReference type="GeneID" id="2684741"/>
    <dbReference type="KEGG" id="mgr:MGG_06586"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06586"/>
    <dbReference type="eggNOG" id="KOG1197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_1"/>
    <dbReference type="InParanoid" id="G4N6A6"/>
    <dbReference type="OMA" id="CDHTIDY"/>
    <dbReference type="OrthoDB" id="48317at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:quinone reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05286">
        <property type="entry name" value="QOR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000053">
        <property type="entry name" value="Quinone oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047618">
        <property type="entry name" value="QOR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF13">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="83"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00070796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="402" mass="43067" checksum="0E8DE9CCE1E394A6" modified="2011-12-14" version="1">MAAIFCNLSASRTIAFSLHLVSAQTRCKPRHLSPKHLQYKSISTATPLPHRRASAQATPPPPLAKAQSRTMATMRAVAFDKTGDSSVLSLREDMPKPTASASQILVKVEWHGINFIDTYMRTGLYQFATPPPHVSGTEGGGIVEAVGAEVPADYGLEVGDRVAFMKSPSAAEYAAVNPNLCFKLPEGVSTKDGAAFLLQGLTAWTLVRDAHEVKPGEVVLVQAAAGGTGGLVVQMCKHLGATVIGTVSTDAKAKLAREHGCDHVVVYTRDDVLKAVNEITHDLGCHAVFSGVGKATFEQDLAATRRKGSFITFGNASGAVEPFSLFKLTARNVRLMRPTLFNFVATREEWDARCRELFDLLAKGVVKTHIGGVYDLSEVAKAQDDLTGQKTVGKLLVKVAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6B6</accession>
    <name>G4N6B6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716957.1">
        <property type="nucleotide sequence ID" value="XM_003716909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6B6"/>
    <dbReference type="STRING" id="242507.G4N6B6"/>
    <dbReference type="GeneID" id="2684733"/>
    <dbReference type="KEGG" id="mgr:MGG_06578"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06578"/>
    <dbReference type="eggNOG" id="ENOG502QTC3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_690926_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6B6"/>
    <dbReference type="OMA" id="QIETHDV"/>
    <dbReference type="OrthoDB" id="2153847at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466653" evidence="2">
        <location>
            <begin position="27"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="399" mass="37726" checksum="D3CB1DF04BD48119" modified="2011-12-14" version="1">MRSNTFFVAILPALVQAIALQERAEGENVQKFTGTLGGAPPPVIKGTGDRPFSVDGDTFVNAGAAIQRSCDRQKNACARQVNSKQIEGSVALCDKQQKDCEAANKGNGAGGAGGAGGAGGAQGNNKAADAGAADNKGAGAKAGDDKKAGAGAADNKGAGAADNKGAGAKAGDDKKAGDDKKAGAGAADNKGAGAKAGDDKKAGDDKKAGDDKKAGADAKGGAAGEKLVAANDKAAADATGGAAGAGAGAGAAGAGAGAGAGAGAGAGAGAGAADPAKDAKKKDDKKKAKMEKQAAKKAAKEAKMKEKKEKKAAEKKKKEEEKAAKDKAKAGAAAAGGAAAGGAAADANKSADAKAGAAGGDAKGSGAADVGKVTRRSGAGKSRGRLATRARIARAVAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6U7</accession>
    <name>G4N6U7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7514 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716233.1">
        <property type="nucleotide sequence ID" value="XM_003716185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6U7"/>
    <dbReference type="GeneID" id="12984362"/>
    <dbReference type="KEGG" id="mgr:MGG_15285"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15285"/>
    <dbReference type="eggNOG" id="KOG2217">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019694_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6U7"/>
    <dbReference type="OMA" id="EVDRWHK"/>
    <dbReference type="OrthoDB" id="5420895at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055936">
        <property type="entry name" value="DUF7514"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611:SF2">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39611">
        <property type="entry name" value="HYDROXYPROLINE-RICH GLYCOPROTEIN DZ-HRGP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24355">
        <property type="entry name" value="DUF7514"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7514" evidence="2">
        <location>
            <begin position="13"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="627" mass="72968" checksum="F51F5BE2DA2FA7F5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4N778</accession>
    <name>G4N778_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Hsp98-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_06459</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717107.1">
        <property type="nucleotide sequence ID" value="XM_003717059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N778"/>
    <dbReference type="SMR" id="G4N778"/>
    <dbReference type="FunCoup" id="G4N778">
        <property type="interactions" value="480"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N778"/>
    <dbReference type="GeneID" id="2684614"/>
    <dbReference type="KEGG" id="mgr:MGG_06459"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06459"/>
    <dbReference type="eggNOG" id="KOG1051">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005070_4_2_1"/>
    <dbReference type="InParanoid" id="G4N778"/>
    <dbReference type="OMA" id="ERMKAVM"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140602">
        <property type="term" value="C:nucleolar peripheral inclusion body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140453">
        <property type="term" value="C:protein aggregate center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000120">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="Double Clp-N motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="10">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="895"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="431"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="899"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA50788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="926" mass="102861" checksum="31E909372AB2A73F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7P7</accession>
    <name>G4N7P7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716371.1">
        <property type="nucleotide sequence ID" value="XM_003716323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7P7"/>
    <dbReference type="STRING" id="242507.G4N7P7"/>
    <dbReference type="GeneID" id="2676623"/>
    <dbReference type="KEGG" id="mgr:MGG_03546"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03546"/>
    <dbReference type="eggNOG" id="ENOG502S9CJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014758_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7P7"/>
    <dbReference type="OMA" id="CRPETSF"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="480"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="648" mass="70465" checksum="5FA3DAB864ED9127" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7R0</accession>
    <name>G4N7R0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716385.1">
        <property type="nucleotide sequence ID" value="XM_003716337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7R0"/>
    <dbReference type="SMR" id="G4N7R0"/>
    <dbReference type="STRING" id="242507.G4N7R0"/>
    <dbReference type="GeneID" id="12984426"/>
    <dbReference type="KEGG" id="mgr:MGG_17079"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17079"/>
    <dbReference type="eggNOG" id="ENOG502QRMK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032013_0_1_1"/>
    <dbReference type="InParanoid" id="G4N7R0"/>
    <dbReference type="OMA" id="ATWNKRE"/>
    <dbReference type="OrthoDB" id="9975579at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.580">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054833">
        <property type="entry name" value="FormamaseFmdA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF045496">
        <property type="entry name" value="FormamaseFmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891:SF1">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141130">
        <property type="entry name" value="Acetamidase/Formamidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="435" mass="47191" checksum="FC97678E2F0633E5" modified="2011-12-14" version="1">MPEIRKVCKVSLDKPAAEQSALHNRWHPDIPFAGTIKNGETVKIECVDWTGGQIGNNDSADDIRNVDLTKIHYLSGPFEVETAEPGDLLLVEIMDVQPFEDQPWGFTGVFDKSNGGGFLDEIYPSAAKAIWDFEGIYCTSRHIPHVKFAGLIHPGILGCAPSAEVLAEWNKREGDLIAANKLERDVAKPPEPVNVHAGAADASLTARVGKEGARTIPGRPEHGGNCDIKNLSRGSKVYLPVHVSGAKFSVGDLHFSQGDGEISFCGAIEMAGVITINFKVIKNGMADLGLKSPIYIPGPVEPHFGPGRHIYFEGFSVDQHGKQHYMDVTVAYRQTCLRVIEYLRRFGYSDYQIYLLMSCAPIQGHIAGIVDIPNACTTLGLPMDIFDFDISPSAVPAKKLDMGTCAFETGVTEGKVTKGGENSEHSFGGGMTYKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8D6</accession>
    <name>G4N8D6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Geranylgeranyl pyrophosphate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_03432</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA50183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="term" value="F:prenyltransferase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:alcohol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0043386">
        <property type="term" value="P:mycotoxin biosynthetic process"/>
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        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
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        <property type="entry name" value="Polyprenyl_synt"/>
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        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G01210)-RELATED"/>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA50183.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="711" mass="79582" checksum="2925D56F968D419B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8H2</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717339.1">
        <property type="nucleotide sequence ID" value="XM_003717291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8H2"/>
    <dbReference type="GeneID" id="12985646"/>
    <dbReference type="KEGG" id="mgr:MGG_17205"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17205"/>
    <dbReference type="eggNOG" id="ENOG502TDCJ">
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    <dbReference type="HOGENOM" id="CLU_151422_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8H2"/>
    <dbReference type="OMA" id="PTETCTK"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <dbReference type="InterPro" id="IPR045634">
        <property type="entry name" value="DUF6413"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19951">
        <property type="entry name" value="DUF6413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466700" evidence="1">
        <location>
            <begin position="17"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="101" mass="10540" checksum="2C332BB00036D350" modified="2011-12-14" version="1">MRSSLLFFMLSVTVSAQPPPVRPDAPIQPELGGRCCAKEGVADPTLTCQKMGLNSFCCTGRRSFISRGCDGGTGNEAVGRHVQGFPPQNGACGFTAFIGCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8J1</accession>
    <name>G4N8J1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">General alpha-glucoside permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_03430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716504.1">
        <property type="nucleotide sequence ID" value="XM_003716456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8J1"/>
    <dbReference type="SMR" id="G4N8J1"/>
    <dbReference type="GeneID" id="2676528"/>
    <dbReference type="KEGG" id="mgr:MGG_03430"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03430"/>
    <dbReference type="eggNOG" id="KOG0637">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018303_1_1_1"/>
    <dbReference type="InParanoid" id="G4N8J1"/>
    <dbReference type="OMA" id="FQWYALF"/>
    <dbReference type="OrthoDB" id="28755at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF35">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="50861" checksum="F09714BF877F1CA9" modified="2011-12-14" version="1">MAASASSSFDDPAEAETAQLMFEFEDFAHQPPAEPLSTRRLLLLTCPSLGLQVCWFLLQTSGTPCLRSLGITPSWISLIWALGPIFGAFVQPVIGQLSDELHHPLGRRKPVMLAGAGAVISSVLAMACALALAPPGAQAWWPRAVAVGCLVVLLFAINAYSVGVRAIVVDVCPPAQQPAAAAWAMRWNVLGSAALSALGVVSTLQGRRDADPVAVFLKLALVAAVLSAVTVGLVCVLVSDTAPPRPKVQEGGGGGVGRVLAMCRLGEIYRRWGRLPPVTGQVCGVQLFAWLGWFPVLYYMSTYAYETALYQASHLTDPEAYAEPYPLYASLSFALGTLLSTLILTLLTATRLLAPAHLPRLWLCSQLLAAVSLLLTMALRTTAAALVLLALVGATWAVTMWVPFALINTELAELGSTGVAGAQGLHNMAVSLPQVASALLCACVLAGLDMLGMAHGAVWLLRLAAVPVGWSTWLIWRLDGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8X5</accession>
    <name>G4N8X5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Initiation-specific alpha-1,6-mannosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716588.1">
        <property type="nucleotide sequence ID" value="XM_003716540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8X5"/>
    <dbReference type="STRING" id="242507.G4N8X5"/>
    <dbReference type="CAZy" id="GT32">
        <property type="family name" value="Glycosyltransferase Family 32"/>
    </dbReference>
    <dbReference type="GeneID" id="2676845"/>
    <dbReference type="KEGG" id="mgr:MGG_03361"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03361"/>
    <dbReference type="eggNOG" id="ENOG502SIMC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022381_2_0_1"/>
    <dbReference type="InParanoid" id="G4N8X5"/>
    <dbReference type="OMA" id="QLNPGHR"/>
    <dbReference type="OrthoDB" id="409543at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.20:FF:000004">
        <property type="entry name" value="Glycosyltransferase family 32 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039367">
        <property type="entry name" value="Och1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834:SF8">
        <property type="entry name" value="TRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="435" mass="48965" checksum="8367CB4290EEE023" modified="2011-12-14" version="1">MGSPRLLGSPLSPLSPKMGMGNLKPAISLRNRLPTQIRRCLPLYLACICIILLILNADIVGISVPGTGVGGRGRGLAIRREAYKDYLSKGKKLQGAGSVPAKFPRKIWQTWKVDPMSFAERDSLTARTWTARNPNFRYEVLTDDNDMGYVEYHFGPDGFDRPDIVEFYRNVNATIIKADLLRYIVMYAEGGVYADIDVEALKPVHRFIPERYNEEDIDLVIGVEIDQPQFRSHPILGSKSQSFCQWTFMAKPRLTVMLNLIENIMSWLNDVAVEQGVGVSEVQLDFDKVISGTGPSAFTIAVLEDMNMRMKLEEAGGRLAKRPSKSGKEITWDDFHDLDESKVVSRILVLDVEAFAAGQGHSDSGNHNARGALVKHHYHASNWPSRHPRFSHPAYGEVERCNWDPVCVAKWDRDVAEFKSLSSEEQQQRIASRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8X6</accession>
    <name>G4N8X6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carboxylic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716589.1">
        <property type="nucleotide sequence ID" value="XM_003716541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8X6"/>
    <dbReference type="SMR" id="G4N8X6"/>
    <dbReference type="STRING" id="242507.G4N8X6"/>
    <dbReference type="GeneID" id="2676844"/>
    <dbReference type="KEGG" id="mgr:MGG_03360"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03360"/>
    <dbReference type="eggNOG" id="ENOG502QPK1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_1_1"/>
    <dbReference type="InParanoid" id="G4N8X6"/>
    <dbReference type="OMA" id="MIPAWIL"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000395">
        <property type="entry name" value="Carboxylic acid transporter protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000465">
        <property type="entry name" value="Carboxylic acid transporter protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <end position="87"/>
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            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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    </feature>
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    </feature>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N916</accession>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
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                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51111.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="105" mass="11986" checksum="B2AB7531C8B7DF5B" modified="2011-12-14" version="1">MILVKASYPGIFKFAGHTRGVLINDNYVAKQNVKWPTESVFWWQDGSTLSSDVREPSSTQGRPDGRQRTHAGHLTDRDDNEKNARRLGTVPVRPWRFPPFPVHVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N937</accession>
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        <recommendedName>
            <fullName evidence="7">Dolichol-phosphate mannosyltransferase subunit 3</fullName>
        </recommendedName>
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        <name evidence="8" type="ORF">MGG_10055</name>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Coughlan S."/>
                <person name="Butler J."/>
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                <person name="Ma L.J."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717451.1">
        <property type="nucleotide sequence ID" value="XM_003717403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N937"/>
    <dbReference type="SMR" id="G4N937"/>
    <dbReference type="STRING" id="242507.G4N937"/>
    <dbReference type="GeneID" id="2681666"/>
    <dbReference type="KEGG" id="mgr:MGG_10055"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10055"/>
    <dbReference type="eggNOG" id="KOG4841">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_150782_1_0_1"/>
    <dbReference type="InParanoid" id="G4N937"/>
    <dbReference type="OMA" id="DCPEAYT"/>
    <dbReference type="OrthoDB" id="2014333at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013174">
        <property type="entry name" value="DPM3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433:SF0">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08285">
        <property type="entry name" value="DPM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA51132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="92" mass="10316" checksum="6C46676E25D7FB94" modified="2011-12-14" version="1">MTRAQQTISILLLATSLYLCLYLQLVPLPDVIQTEVIPVLPFWVLVSFGALLLGRLGWGVLTFNDTPEAHKELLVEIEEAKKDLRRLGVTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N983</accession>
    <name>G4N983_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03314</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716646.1">
        <property type="nucleotide sequence ID" value="XM_003716598.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N983"/>
    <dbReference type="STRING" id="242507.G4N983"/>
    <dbReference type="GeneID" id="2676668"/>
    <dbReference type="KEGG" id="mgr:MGG_03314"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03314"/>
    <dbReference type="eggNOG" id="KOG1858">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000746_0_0_1"/>
    <dbReference type="InParanoid" id="G4N983"/>
    <dbReference type="OMA" id="YIGTMDS"/>
    <dbReference type="OrthoDB" id="26401at2759"/>
    <dbReference type="PHI-base" id="PHI:2215"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000283">
        <property type="entry name" value="Anaphase-promoting complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000531">
        <property type="entry name" value="Negative regulator of mitosis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046794">
        <property type="entry name" value="Apc1_MidN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049255">
        <property type="entry name" value="Apc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12859">
        <property type="entry name" value="ANAPC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20518">
        <property type="entry name" value="Apc1_MidN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 N-terminal" evidence="6">
        <location>
            <begin position="29"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 middle" evidence="7">
        <location>
            <begin position="1030"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="322"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="782"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1771"/>
            <end position="1790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1842"/>
            <end position="1871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="792"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA50327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="2081" mass="229089" checksum="228D19125489081A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9N4</accession>
    <name>G4N9N4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717541.1">
        <property type="nucleotide sequence ID" value="XM_003717493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9N4"/>
    <dbReference type="GeneID" id="2680955"/>
    <dbReference type="KEGG" id="mgr:MGG_09969"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09969"/>
    <dbReference type="eggNOG" id="ENOG502RYFN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047435_1_0_1"/>
    <dbReference type="InParanoid" id="G4N9N4"/>
    <dbReference type="OMA" id="WFSTQWH"/>
    <dbReference type="OrthoDB" id="9971601at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142">
        <property type="entry name" value="METALLO-HYDROLASE/OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36142:SF2">
        <property type="entry name" value="METALLO-HYDROLASE_OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="44341" checksum="9B523DF1E1079807" modified="2011-12-14" version="1">MMTSIDAPGRLSKIPCLLRISASNNLIHRAYQNKDPDTMDEQNSVTPQPREVFNSSNRDQWRAALVAQEPVLIHLNADTTWLLQIPYPHNAENPYGRSHFNILIDPWLQGPQSDVASWFSTQWHVVEPSVATIAALNKVLGELDEAANLLRNDSSSGKADTTTDKNKKARPNSWFIDAVVISHEFTDHCHRATLEELPKSTPVIAGDEAAKLIQSWDHFDEVITTPPFSSQSASWQEAMADCHPILPKWLGIGRVVTAGNALYYHSAVIVAFGSETQAEAVLYSPHGIDAQDLAFLPKSGLKTLALLHGLHDVRIWMTKQLNLGALNGLRVVRACGAKYWVATHDEVKRGGGLISWMLQRTVYSLKDAVKAEEARIKADADQEDVGSYQFLELGSGGAIVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB27</accession>
    <name>G4NB27_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718373.1">
        <property type="nucleotide sequence ID" value="XM_003718325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB27"/>
    <dbReference type="GeneID" id="12984073"/>
    <dbReference type="KEGG" id="mgr:MGG_17400"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17400"/>
    <dbReference type="HOGENOM" id="CLU_880207_0_0_1"/>
    <dbReference type="InParanoid" id="G4NB27"/>
    <dbReference type="OrthoDB" id="4717190at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="316" mass="34166" checksum="B2A5F47A655C286A" modified="2011-12-14" version="1">MPGDAGAVSKTLDKFLSKGLRAVELFPRISLATAARLPAPLSAPVCQWAQGLFVGLLARRLQLLAKSGAPRTGSELQHADPSHICARGRGVRPARVPRSHPPTLLRGHAPLLDHVLGLPVFHRVGRRARGPDVADLAASYLLLAAGRIAWVARRGDRRLHRRETGRYLSVVGGGKPWIVDRELGRLMGEDDRFLQLEVGTWILERRDGPEANAGAFRPYHPVSRCYLATSFRTHVDRGRSGISNDTVAQVIGRVSEAVCTRGVISDASVLGVVKGHDPVRHISWDRSGWRGLGLLGLPDEPGQGFVVAGLDARAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBB5</accession>
    <name>G4NBB5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00583</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718461.1">
        <property type="nucleotide sequence ID" value="XM_003718413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBB5"/>
    <dbReference type="SMR" id="G4NBB5"/>
    <dbReference type="STRING" id="242507.G4NBB5"/>
    <dbReference type="CAZy" id="GH2">
        <property type="family name" value="Glycoside Hydrolase Family 2"/>
    </dbReference>
    <dbReference type="GeneID" id="2674946"/>
    <dbReference type="KEGG" id="mgr:MGG_00583"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00583"/>
    <dbReference type="eggNOG" id="KOG2024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002346_0_2_1"/>
    <dbReference type="InParanoid" id="G4NBB5"/>
    <dbReference type="OMA" id="WCDHGIL"/>
    <dbReference type="OrthoDB" id="408320at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005990">
        <property type="term" value="P:lactose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000018">
        <property type="entry name" value="Beta-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050347">
        <property type="entry name" value="Bact_Beta-galactosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
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        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46323:SF2">
        <property type="entry name" value="BETA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="LacZ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta galactosidase small chain/" evidence="7">
        <location>
            <begin position="789"/>
            <end position="1071"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1071" mass="121699" checksum="0B96F22C59877781" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBF5</accession>
    <name>G4NBF5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718496.1">
        <property type="nucleotide sequence ID" value="XM_003718448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBF5"/>
    <dbReference type="GeneID" id="2674515"/>
    <dbReference type="KEGG" id="mgr:MGG_00554"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00554"/>
    <dbReference type="HOGENOM" id="CLU_1475457_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBF5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="183" mass="19325" checksum="53072C0017700F02" modified="2011-12-14" version="1">MVLAQSRAPDPKFAFLHKQGGSGLAQPRLDGVLSHRVDEAILAAPREWDGGRGRSPLLRGSRGRGKSGGECRAAGRASVCPQLRSEARSVVVEGLLVVVDVKLAVVVDVVLGKELEAASVVSSAQLVVDEGFDKDLDVAVGTGSVDPDVHIPNSGSYWMESIARKGTVPWGDDPSYAVFRNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBQ3</accession>
    <name>G4NBQ3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_00512</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718545.1">
        <property type="nucleotide sequence ID" value="XM_003718497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBQ3"/>
    <dbReference type="GeneID" id="2674757"/>
    <dbReference type="KEGG" id="mgr:MGG_00512"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00512"/>
    <dbReference type="HOGENOM" id="CLU_2050106_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBQ3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="120" mass="13251" checksum="F51D6433535F6D2D" modified="2011-12-14" version="1">MARCCKCRFRHFWKPRPHSPTYVKERPALIDDAKCKESAARSSSTGLPGSPSIAAATYLGTLCTREKRISPNSIDGFLFAPDPNEWDLAPCQPIKVLCGVERSAVVPAWRLPHSLDPSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC16</accession>
    <name>G4NC16_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial 2-oxoglutarate/malate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_17450</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718603.1">
        <property type="nucleotide sequence ID" value="XM_003718555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC16"/>
    <dbReference type="SMR" id="G4NC16"/>
    <dbReference type="STRING" id="242507.G4NC16"/>
    <dbReference type="GeneID" id="12984126"/>
    <dbReference type="KEGG" id="mgr:MGG_17450"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17450"/>
    <dbReference type="eggNOG" id="KOG0759">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_14_1_1"/>
    <dbReference type="InParanoid" id="G4NC16"/>
    <dbReference type="OMA" id="TLWRGAI"/>
    <dbReference type="OrthoDB" id="756301at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000009">
        <property type="entry name" value="Mitochondrial 2-oxoglutarate/malate carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="44"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="145"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="244"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA49019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="336" mass="35849" checksum="336A243A3E754A70" modified="2011-12-14" version="1">MSNSIKQAAEAVRSRTSEVMGGAGKGSGGETAAVANDFLHTPFMRAALPFLNGGAAGMVATTVIQPVDMIKVRLQLAGEGMAGGVKPTPLSVTRDILASGRALDLYTGLSAGLLRQAVYTTARLGFFDTFMGTLTAKAKENGSAIGFKERAAAGLSAGGLAAMIGNPADLALIRMQSDGLKPKESRQNYKSVIDALARITKNEGIAALWSGATPTVVRAMALNFGQLAFFSEAKAQLKSRTDLNPRVQTLTASAVAGFFASFFSLPFDFVKTRLQKQQRGPDGKLPYRNMIDCFGQVAKQEGALRFYRGFWTYYVRIAPHAMVTLIVADYLGWITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCE1</accession>
    <name>G4NCE1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_00402</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718674.1">
        <property type="nucleotide sequence ID" value="XM_003718626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCE1"/>
    <dbReference type="SMR" id="G4NCE1"/>
    <dbReference type="STRING" id="242507.G4NCE1"/>
    <dbReference type="GeneID" id="2674230"/>
    <dbReference type="KEGG" id="mgr:MGG_00402"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00402"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_3_1"/>
    <dbReference type="InParanoid" id="G4NCE1"/>
    <dbReference type="OMA" id="HDPAQKS"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF152">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="331" mass="36215" checksum="3BAE11BF38BC772D" modified="2011-12-14" version="1">MHLQTRMSGFKYSIIITGGTAGMGFAAATQMAKDCPDHLIVIASRSSNDDAAGAINKSLNQSNTQFLPIDLANPTDVRRFARDWMADESKPPIKALVFNAALQFPNGLTLTPDGMEKTFAIAHAGHALLFHLLFPRLVPRGARVVLTSSGTHDPAQRSGMPDPVYTTAAQVAYPPPERAALPSRAHYTTAKLCNVLWAYALARHLGDAVPERSVSVTAMDPGLMPGTGLARETTRVQRWLWVAVLPRLLWLLRMVFSPNVHTAEESGRSLARLAVGADVEGVTGRYFEGREEIMSSKDSYSEKLQEDLWDWTVNFVAGGDKAEAERLNAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCJ5</accession>
    <name>G4NCJ5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717876.1">
        <property type="nucleotide sequence ID" value="XM_003717828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCJ5"/>
    <dbReference type="SMR" id="G4NCJ5"/>
    <dbReference type="STRING" id="242507.G4NCJ5"/>
    <dbReference type="GeneID" id="2675213"/>
    <dbReference type="KEGG" id="mgr:MGG_01063"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01063"/>
    <dbReference type="eggNOG" id="ENOG502RS64">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013811_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCJ5"/>
    <dbReference type="OMA" id="DAKYRKC"/>
    <dbReference type="OrthoDB" id="49395at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd22211">
        <property type="entry name" value="HkD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Calponin-like domain"/>
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    </dbReference>
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        <property type="entry name" value="CH_dom_sf"/>
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        <property type="entry name" value="Hook domain"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="434"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="203"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="634"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="775" mass="88142" checksum="5C9CDDD4ECD586C4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCP8</accession>
    <name>G4NCP8_PYRO7</name>
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        <submittedName>
            <fullName evidence="8">DNA cross-link repair protein SNM1</fullName>
        </submittedName>
    </protein>
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        <name evidence="8" type="ORF">MGG_11590</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_11590"/>
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        <property type="component" value="Chromosome 5"/>
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    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16273">
        <property type="entry name" value="SNM1A-1C-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12650:FF:000007">
        <property type="entry name" value="DNA cross-link repair 1A protein, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000038">
        <property type="entry name" value="DNA cross-link repair protein pso2/snm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF6">
        <property type="entry name" value="DNA CROSS-LINK REPAIR 1A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="695"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="87"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="618"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="857"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="136"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="147"/>
            <end position="175"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="217"/>
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    </feature>
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            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="620"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="869"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA49142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="886" mass="97116" checksum="ED533DE5C16FB0A3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCR4</accession>
    <name>G4NCR4_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme E2C-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718742.1">
        <property type="nucleotide sequence ID" value="XM_003718694.1"/>
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    <dbReference type="KEGG" id="mgr:MGG_00340"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00340"/>
    <dbReference type="eggNOG" id="KOG4784">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_071320_1_0_1"/>
    <dbReference type="InParanoid" id="G4NCR4"/>
    <dbReference type="OMA" id="DHADHNH"/>
    <dbReference type="OrthoDB" id="66510at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
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    <dbReference type="GO" id="GO:0005829">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:cyclin binding"/>
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        <property type="term" value="P:protein polyubiquitination"/>
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    <dbReference type="InterPro" id="IPR019193">
        <property type="entry name" value="UBQ-conj_enz_E2-bd_prot"/>
    </dbReference>
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        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE E3D"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09814">
        <property type="entry name" value="HECT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="29348" checksum="375D1729A6C4A280" modified="2011-12-14" version="1">MADNFSIYAELLPNIRQVSVVASLPSPCDSSTRALLLSNGSRIHVTHHDDSRLLELPAAVVQGGGGSPATLPLKPAADNGCKLTWRFPLDLAYSASAAPQGAIATGGGAGSSVPWEAVNIAGGSTVLCRGCKAVLVPGERIKEWKDLPSANWAEMMEFWHCHKPDDHDAEDGHRHHGHDYDDHRIKGGDKADEQTLAGRGYGANSSIQAQRGVGFVDLMTFLFAEDECRGVEFETCLGCNAAFWVSGNGSGNAAFGGRMATLYFTEACTQWTSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDM7</accession>
    <name>G4NDM7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat and SOCS box protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_11634</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718896.1">
        <property type="nucleotide sequence ID" value="XM_003718848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDM7"/>
    <dbReference type="SMR" id="G4NDM7"/>
    <dbReference type="STRING" id="242507.G4NDM7"/>
    <dbReference type="GeneID" id="5050798"/>
    <dbReference type="KEGG" id="mgr:MGG_11634"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11634"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014021_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDM7"/>
    <dbReference type="OMA" id="PNKVYRG"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="475"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="544"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="579"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="643"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="766"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="178"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA49312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="990" mass="107261" checksum="B8A9F76C97118822" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDT1</accession>
    <name>G4NDT1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_11478</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718103.1">
        <property type="nucleotide sequence ID" value="XM_003718055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDT1"/>
    <dbReference type="GeneID" id="5050639"/>
    <dbReference type="KEGG" id="mgr:MGG_11478"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11478"/>
    <dbReference type="HOGENOM" id="CLU_1570941_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDT1"/>
    <dbReference type="OMA" id="WNSIENW"/>
    <dbReference type="OrthoDB" id="3853613at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="170" mass="18803" checksum="0351E5EE207A32A3" modified="2011-12-14" version="1">MAAQAKFHVGCKPVGGRLATRTIKAENVFFYPEIWNSIENWDKLALKDRVFALHSRCLHFAAINKSETAKAAVSVVADSIVKAASSQSLVASRSEHLGALVDLMVSFYEETEDPIYLGAINWILERTDPDLEYGPRTFTSGMGAFANFEEDLTEEAAIHLQAELIVRILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEG2</accession>
    <name>G4NEG2_PYRO7</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">MGG_17532</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719023.1">
        <property type="nucleotide sequence ID" value="XM_003718975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEG2"/>
    <dbReference type="SMR" id="G4NEG2"/>
    <dbReference type="STRING" id="242507.G4NEG2"/>
    <dbReference type="GeneID" id="12985125"/>
    <dbReference type="KEGG" id="mgr:MGG_17532"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17532"/>
    <dbReference type="eggNOG" id="ENOG502S8JK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077442_2_0_1"/>
    <dbReference type="InParanoid" id="G4NEG2"/>
    <dbReference type="OMA" id="DVWSKPP"/>
    <dbReference type="OrthoDB" id="42525at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009784">
        <property type="entry name" value="DUF1349"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35332:SF2">
        <property type="entry name" value="REGULATION OF ENOLASE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07081">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466436" evidence="1">
        <location>
            <begin position="24"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="230" mass="25104" checksum="F5BC569C3977F6B3" modified="2011-12-14" version="1">MLSFLSRSILIVAFANVLVLCSANPHSHQRYSIMSSFNIKAAPGTDIWRKPPTTDVYNAPTHAPAGTKTTAPLSKFKSAQVSFTFKPTEQYDQGGVVLSFTPPEGQGNSTSPKKWVKSGVEMLNGTPLLGTVATDRWADWSISPVALKPDGKTVDATIFLQKEGDENGVSLWVYGVGADGVKKTLREICWVFADDMKDWELKVEAYAARPKGSTEELDVEFGGLEVTWSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEH0</accession>
    <name>G4NEH0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17535</name>
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    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719031.1">
        <property type="nucleotide sequence ID" value="XM_003718983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEH0"/>
    <dbReference type="STRING" id="242507.G4NEH0"/>
    <dbReference type="GeneID" id="12985129"/>
    <dbReference type="KEGG" id="mgr:MGG_17535"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17535"/>
    <dbReference type="eggNOG" id="ENOG502RYBR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020985_1_1_1"/>
    <dbReference type="InParanoid" id="G4NEH0"/>
    <dbReference type="OMA" id="CANTHTS"/>
    <dbReference type="OrthoDB" id="3021074at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="552" mass="60583" checksum="EE50E3F88FC741A0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEJ4</accession>
    <name>G4NEJ4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00083</name>
    </gene>
    <organism evidence="3 4">
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        <lineage>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719055.1">
        <property type="nucleotide sequence ID" value="XM_003719007.1"/>
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    <dbReference type="AlphaFoldDB" id="G4NEJ4"/>
    <dbReference type="SMR" id="G4NEJ4"/>
    <dbReference type="GeneID" id="2675051"/>
    <dbReference type="KEGG" id="mgr:MGG_00083"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00083"/>
    <dbReference type="HOGENOM" id="CLU_956686_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEJ4"/>
    <dbReference type="OMA" id="DNVQEYD"/>
    <dbReference type="OrthoDB" id="10611714at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466526" evidence="2">
        <location>
            <begin position="18"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="291" mass="31654" checksum="860312D610A02676" modified="2011-12-14" version="1">MRFETLIVSLLASAAVAVPMNGDGASAALQARSEAPGNGPMPAHFAKRDPKSPGEVKEDLKKKIEADKEKARKKLEEAKKRLPKIPHLNITKPGMPPRQQVKRAAAKDMFSDPQVPVAVKKKGEDAKKKAEDAKKKAEDAKKKSPPKVGVPVGKNNTKPGKPPKKSEPKKATPKRSVTLEERDPLNLGDIGKDIKKELEKLRHKFGKPKNGTAPAAPAEPAANQKRDVEAEAKKDCDKKKDGKKPRKDRKGGKKNNGPKRPGKNSTMPMPKPKPATPKGKRSLPVRLPAMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEN4</accession>
    <name>G4NEN4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_00752</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718248.1">
        <property type="nucleotide sequence ID" value="XM_003718200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEN4"/>
    <dbReference type="FunCoup" id="G4NEN4">
        <property type="interactions" value="561"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NEN4"/>
    <dbReference type="GeneID" id="2674860"/>
    <dbReference type="KEGG" id="mgr:MGG_00752"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00752"/>
    <dbReference type="eggNOG" id="KOG1944">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049109_8_1_1"/>
    <dbReference type="InParanoid" id="G4NEN4"/>
    <dbReference type="OMA" id="WYQSKLA"/>
    <dbReference type="OrthoDB" id="430207at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA48664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="197" mass="22000" checksum="2B778424BD218CE0" modified="2011-12-14" version="1">MVFAWYQARLAARPLLTQSITTAVLFATGDITAQQLVEKRGLEKHDFVRTGRMFAYGGIIFGPAATTWFGILQRHVVLKNANATILARVAVDQGLFAPTFVGVFLSSMAILEGSSPQEKLKSTYSTALTSNYMLWPFVQLVNFKFVPLHHRVLFVNVISIGWNCYLSFLNSGAPNKIDEVIEEGEEKVEELIEKVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEP1</accession>
    <name>G4NEP1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_00744</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718255.1">
        <property type="nucleotide sequence ID" value="XM_003718207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEP1"/>
    <dbReference type="SMR" id="G4NEP1"/>
    <dbReference type="FunCoup" id="G4NEP1">
        <property type="interactions" value="1048"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NEP1"/>
    <dbReference type="GeneID" id="2674802"/>
    <dbReference type="KEGG" id="mgr:MGG_00744"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00744"/>
    <dbReference type="eggNOG" id="KOG1993">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003886_1_0_1"/>
    <dbReference type="InParanoid" id="G4NEP1"/>
    <dbReference type="OMA" id="SFHYVFH"/>
    <dbReference type="OrthoDB" id="361693at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000362">
        <property type="entry name" value="Importin 11, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058669">
        <property type="entry name" value="TPR_IPO7/11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF7">
        <property type="entry name" value="IMPORTIN-11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25758">
        <property type="entry name" value="TPR_IPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="5">
        <location>
            <begin position="37"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA48671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1049" mass="117955" checksum="42578AEDCC62A1AA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFC7</accession>
    <name>G4NFC7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">MFS quinate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_04225</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719588.1">
        <property type="nucleotide sequence ID" value="XM_003719540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFC7"/>
    <dbReference type="SMR" id="G4NFC7"/>
    <dbReference type="GeneID" id="2677208"/>
    <dbReference type="KEGG" id="mgr:MGG_04225"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04225"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_12_1"/>
    <dbReference type="InParanoid" id="G4NFC7"/>
    <dbReference type="OMA" id="KEIYGWR"/>
    <dbReference type="OrthoDB" id="508119at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF21">
        <property type="entry name" value="QUINATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06960)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="33"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="536" mass="58738" checksum="6C8CB1EC697F6C58" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFL6</accession>
    <name>G4NFL6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08783</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719190.1">
        <property type="nucleotide sequence ID" value="XM_003719142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFL6"/>
    <dbReference type="SMR" id="G4NFL6"/>
    <dbReference type="STRING" id="242507.G4NFL6"/>
    <dbReference type="GeneID" id="2679005"/>
    <dbReference type="KEGG" id="mgr:MGG_08783"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08783"/>
    <dbReference type="eggNOG" id="KOG2456">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023881_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFL6"/>
    <dbReference type="OMA" id="CHNAFFR"/>
    <dbReference type="OrthoDB" id="5596991at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43111">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43111:SF1">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="3">
        <location>
            <begin position="33"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="522" mass="55036" checksum="4B8A8A34F6277B35" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFN6</accession>
    <name>G4NFN6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="4 12">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_14133</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the phage and mitochondrial RNA polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="4 12"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719210.1">
        <property type="nucleotide sequence ID" value="XM_003719162.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NFN6"/>
    <dbReference type="FunCoup" id="G4NFN6">
        <property type="interactions" value="251"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NFN6"/>
    <dbReference type="GeneID" id="5048672"/>
    <dbReference type="KEGG" id="mgr:MGG_14133"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14133"/>
    <dbReference type="eggNOG" id="KOG1038">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003364_1_0_1"/>
    <dbReference type="InParanoid" id="G4NFN6"/>
    <dbReference type="OMA" id="KWFEVDM"/>
    <dbReference type="OrthoDB" id="276422at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001018">
        <property type="term" value="F:mitochondrial promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006390">
        <property type="term" value="P:mitochondrial transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.280:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024075">
        <property type="entry name" value="DNA-dir_RNA_pol_helix_hairp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046950">
        <property type="entry name" value="DNA-dir_Rpol_C_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00940">
        <property type="entry name" value="RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00900">
        <property type="entry name" value="RNA_POL_PHAGE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00489">
        <property type="entry name" value="RNA_POL_PHAGE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 15" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="14">
        <location>
            <begin position="347"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="280"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1288"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1302"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1314"/>
            <end position="1347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA46843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1422" mass="159088" checksum="182C82B20DBCE713" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGM4</accession>
    <name>G4NGM4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thiosulfate sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_04087</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719751.1">
        <property type="nucleotide sequence ID" value="XM_003719703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGM4"/>
    <dbReference type="SMR" id="G4NGM4"/>
    <dbReference type="FunCoup" id="G4NGM4">
        <property type="interactions" value="469"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGM4"/>
    <dbReference type="GeneID" id="2677679"/>
    <dbReference type="KEGG" id="mgr:MGG_04087"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04087"/>
    <dbReference type="eggNOG" id="KOG1529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031618_3_1_1"/>
    <dbReference type="InParanoid" id="G4NGM4"/>
    <dbReference type="OMA" id="NNNWFAS"/>
    <dbReference type="OrthoDB" id="270167at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01448">
        <property type="entry name" value="TST_Repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01449">
        <property type="entry name" value="TST_Repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000001">
        <property type="entry name" value="Sulfurtransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000033">
        <property type="entry name" value="Thiosulfate sulfurtransferase TUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364:SF27">
        <property type="entry name" value="SULFURTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="THIOSULFATE SULFERTANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="89"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="230"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="355" mass="39356" checksum="BBF4D29BA8E70F2F" modified="2011-12-14" version="1">MSPATLITFTMPTTSWAPRAAAKVRSTPIFCPTTASRTFATSMPRRTFSSYLVTPKEVHEAMQKSPPSSISTHPRVICLNAAWFLPNDPEGRTGIESYRKTRIPKSRFFDLDKVIDRHSPYPHMLPEPKSFASAMSELGVRREDTVVVYDTKELGIFSAPRVAWTLRVFGHPKVHILNNFRAWCDEELPIESGNLYNVECCTYPIPEISADKVADFEEVRDVAMDHNKEGAEGVQILDARSAGRFDGSAAEPRPGLSSGHMPGAINVPIDTLLDPKTKAFLPADQLRKVFESKGVDPFKPIVSTCGTGVTACIIDTALEVAQFGNPEKRKVYDGSWTEWAQRVKPSDSLIRKSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="78" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGS3</accession>
    <name>G4NGS3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_04042</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719800.1">
        <property type="nucleotide sequence ID" value="XM_003719752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGS3"/>
    <dbReference type="SMR" id="G4NGS3"/>
    <dbReference type="FunCoup" id="G4NGS3">
        <property type="interactions" value="512"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGS3"/>
    <dbReference type="GeneID" id="2677156"/>
    <dbReference type="KEGG" id="mgr:MGG_04042"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04042"/>
    <dbReference type="eggNOG" id="KOG0435">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004427_2_0_1"/>
    <dbReference type="InParanoid" id="G4NGS3"/>
    <dbReference type="OMA" id="GIEHACM"/>
    <dbReference type="OrthoDB" id="15954at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00812">
        <property type="entry name" value="LeuRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000002">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000003">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000338">
        <property type="entry name" value="Leucine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000034">
        <property type="entry name" value="Leucine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740:SF2">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="14">
        <location>
            <begin position="104"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Leucyl-tRNA synthetase editing" evidence="15">
        <location>
            <begin position="289"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="496"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="704"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="13">
        <location>
            <begin position="795"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA47433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="973" mass="108445" checksum="914CFC8BBF828073" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH71</accession>
    <name>G4NH71_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein phosphatase 1K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_03918</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719948.1">
        <property type="nucleotide sequence ID" value="XM_003719900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH71"/>
    <dbReference type="SMR" id="G4NH71"/>
    <dbReference type="STRING" id="242507.G4NH71"/>
    <dbReference type="GeneID" id="2677456"/>
    <dbReference type="KEGG" id="mgr:MGG_03918"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03918"/>
    <dbReference type="eggNOG" id="KOG0698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021251_2_0_1"/>
    <dbReference type="InParanoid" id="G4NH71"/>
    <dbReference type="OMA" id="FKGGSTC"/>
    <dbReference type="OrthoDB" id="416093at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF589">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="6">
        <location>
            <begin position="219"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="120"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="283"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="442"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="667"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="183"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="678"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA47581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="696" mass="75548" checksum="60C6F2B8DAA50633" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHH3</accession>
    <name>G4NHH3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720050.1">
        <property type="nucleotide sequence ID" value="XM_003720002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHH3"/>
    <dbReference type="GeneID" id="12987130"/>
    <dbReference type="KEGG" id="mgr:MGG_17741"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17741"/>
    <dbReference type="HOGENOM" id="CLU_2812904_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHH3"/>
    <dbReference type="OrthoDB" id="10349988at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="67" mass="7644" checksum="3D0391D076B98625" modified="2011-12-14" version="1">MSEVPWYARNAKRTGDRLTHKHSGQRRGPRKCWRPSGGWTRPVLDLTGAAWVLALWFGHKAQTVTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHN6</accession>
    <name>G4NHN6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_12049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720113.1">
        <property type="nucleotide sequence ID" value="XM_003720065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHN6"/>
    <dbReference type="GeneID" id="5049820"/>
    <dbReference type="KEGG" id="mgr:MGG_12049"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12049"/>
    <dbReference type="HOGENOM" id="CLU_1816194_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHN6"/>
    <dbReference type="OMA" id="CCSFANH"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466963" description="Chitin-binding type-1 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="13980" checksum="DA19580E3AC62B9E" modified="2011-12-14" version="1">MMRFAAISTILLGSLHGAIGAVLPAAVPAATSLGGAGNSGPWCGITGNQNEVTLTCATLPGSTAKACCSFANHCGTGPDYCGDGCQTAFGDCAPSTKTSINNFANLGTSVFSAHYPNVNAAPRIIAPVKPLGSSPGGLKPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHV1</accession>
    <name>G4NHV1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxymethylenebutenolidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_09427</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720178.1">
        <property type="nucleotide sequence ID" value="XM_003720130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHV1"/>
    <dbReference type="SMR" id="G4NHV1"/>
    <dbReference type="STRING" id="242507.G4NHV1"/>
    <dbReference type="GeneID" id="2680391"/>
    <dbReference type="KEGG" id="mgr:MGG_09427"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09427"/>
    <dbReference type="eggNOG" id="ENOG502QWD6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032662_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHV1"/>
    <dbReference type="OMA" id="THNQEIP"/>
    <dbReference type="OrthoDB" id="5440at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436:SF3">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="POLYKETIDE CYCLASE SNOAL-LIKE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="45273" checksum="600E2AA0366930F7" modified="2011-12-14" version="1">MSTYSDISKPAPPLPTTNLKSIGSGVSLLAPLSRRGHGPGIILLVPDHEDQLTISQGVPSLLVKWAEEGYAVVEIQRKALEGDAAAAVSLAVDGLAGCEACQPKDKIGVVAYDPYAWNLSAESINKVPSIAAVAIYTDVDQTQSLAATSVPTIHHVAGKSSTPPVRSEALTAYHYPGTTSHAFATPFQPTFSYTTEALSHTRNLNLLKRHMGGPNFDLEQIWDEHCHYEFVDRSAEHTMSTMVQEPYVNHVPVLTGGVGREPLTSFYRSHFIFSNASDAELELVSRSVAIDRVIDEFIFKCTHNLEIDWLVPGIPPTGKKLEIPFTAVVNIRGDRLFHEHISWDQGTVLRQLGLMPEYLPFPYPMPDGRTPEPGKRFEYRVPVAGVETANKMRDRNSVSSNGMFQFRVREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NID1</accession>
    <name>G4NID1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720358.1">
        <property type="nucleotide sequence ID" value="XM_003720310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NID1"/>
    <dbReference type="SMR" id="G4NID1"/>
    <dbReference type="STRING" id="242507.G4NID1"/>
    <dbReference type="GeneID" id="2680786"/>
    <dbReference type="KEGG" id="mgr:MGG_09876"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09876"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_642627_0_0_1"/>
    <dbReference type="InParanoid" id="G4NID1"/>
    <dbReference type="OMA" id="CYRDIAY"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="77"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="427" mass="47473" checksum="C6D8292CB2812EA6" modified="2011-12-14" version="1">MPPKPTAMLLCSGCKACQRNAWKTFHKLECKAVLSEAPAMGPTTLAMYRLLLLKKDGRFTERQWKAIMQLESHFEEQNEDLRNDILAKVHGWGRRMGTDVDFMTVWELLCIIFTNSMNVRPAEADVSFGTSLDLVVSMINHDCSPNAHVFFEGSQVRVRSLKAIAAGGEITVSYCDPRLDVLLRQEILRQTQFFHCECNCTSGFYSVLKGSEAAKTEMLSQFAAAIETMTKSGYGGHAWPAHVEPLPNVRMTLAGMFKAGFSYVPALKYALAGCLMAGRRCGSPFVQDLLELVRILVQTCNEPGDGMPFTVQNFPTKKELQMLTMGYIVILCKAVRLAFGTDCRYTLMVWAWARTFMGAGAGGVPALGQTVFEEQFEKVQKKLASWAEVDRLLNLGDRRELVTTVVDVIKAFETYTIKPGIVSPAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIG9</accession>
    <name>G4NIG9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720396.1">
        <property type="nucleotide sequence ID" value="XM_003720348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIG9"/>
    <dbReference type="SMR" id="G4NIG9"/>
    <dbReference type="GeneID" id="2680842"/>
    <dbReference type="KEGG" id="mgr:MGG_09843"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09843"/>
    <dbReference type="HOGENOM" id="CLU_1210042_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIG9"/>
    <dbReference type="OMA" id="TEPIAPM"/>
    <dbReference type="OrthoDB" id="5229650at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="229" mass="25948" checksum="D0C4376FA6BA73C7" modified="2011-12-14" version="1">MSLTDLETKMLETAQQQIELQKRDVTRLEQTIERKRTRAEAYRLKTAQALETLTETKESLCDFDSVIAKFEGMETSLSAHRQRAEAKTQLLGQARAPSLAAEVTSFEHLESATQQHRQVASSLARARAQRCALGRRVQAAEEEYDYVVHDERVCAEVVRGFEETLRESRHKYQALLVVADADNLAGYESETDKIRRDGDATVVSVASHIYQLVTCTEPIAPMHHLWMPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIJ1</accession>
    <name>G4NIJ1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7580 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720418.1">
        <property type="nucleotide sequence ID" value="XM_003720370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIJ1"/>
    <dbReference type="GeneID" id="2680855"/>
    <dbReference type="KEGG" id="mgr:MGG_09822"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09822"/>
    <dbReference type="eggNOG" id="ENOG502SP4W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1170837_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIJ1"/>
    <dbReference type="OMA" id="YASSWMQ"/>
    <dbReference type="OrthoDB" id="3565018at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056002">
        <property type="entry name" value="DUF7580"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24476">
        <property type="entry name" value="DUF7580"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7580" evidence="1">
        <location>
            <begin position="12"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="237" mass="26966" checksum="B18698B70CD9FD1A" modified="2011-12-14" version="1">MESVGVAQSKLSVEDGVLWYHGFQSSKLPPYLLRSPSLSLRQLLEKLDRREVSGHHKLTLQVQIVKAFWQFYASSWMQRTWNKDLVHFLFQRRGQSSQEIKVDDPFLEIRFDMAAPGQQRVEQYPYFTWPPIHSLGVILLEIELVDCIDRAVQDYGFLSESTGRPKQNAELFAAEYAVKCDHILDNDETYPEVASSSNPALMRHRISIGYTTAAVTGGPKFDTAQSSKRQPVGNSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIJ3</accession>
    <name>G4NIJ3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_09821</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720420.1">
        <property type="nucleotide sequence ID" value="XM_003720372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIJ3"/>
    <dbReference type="SMR" id="G4NIJ3"/>
    <dbReference type="GeneID" id="2680854"/>
    <dbReference type="KEGG" id="mgr:MGG_09821"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09821"/>
    <dbReference type="eggNOG" id="ENOG502SJPU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013756_1_0_1"/>
    <dbReference type="InParanoid" id="G4NIJ3"/>
    <dbReference type="OMA" id="QRAIYFG"/>
    <dbReference type="OrthoDB" id="10029326at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF8">
        <property type="entry name" value="MFS GENERAL SUBSTRATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="497"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="533"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="450"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA48053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="59995" checksum="D3B57B0B331557F6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIY5</accession>
    <name>G4NIY5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioesterase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17959</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720944.1">
        <property type="nucleotide sequence ID" value="XM_003720896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIY5"/>
    <dbReference type="SMR" id="G4NIY5"/>
    <dbReference type="GeneID" id="12984841"/>
    <dbReference type="KEGG" id="mgr:MGG_17959"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17959"/>
    <dbReference type="eggNOG" id="ENOG502S4UX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050730_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIY5"/>
    <dbReference type="OMA" id="CDMFITP"/>
    <dbReference type="OrthoDB" id="2532955at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049450">
        <property type="entry name" value="ACOT8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052389">
        <property type="entry name" value="Sec_Metab_Biosynth-Assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38110">
        <property type="entry name" value="CHROMOSOME 23, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38110:SF1">
        <property type="entry name" value="THIOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20789">
        <property type="entry name" value="4HBT_3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="1">
        <location>
            <begin position="41"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase-like C-terminal" evidence="2">
        <location>
            <begin position="194"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="41139" checksum="5108A1C8A65110F0" modified="2011-12-14" version="1">MGPPSSASSQPATPKVTLAEASEVRALDANIYSANFHKAFRIAMVPHGGYVATCFLRVAALHLRRSSRDQPDTMTAHLEYLDRTEVGPAIFVVEEMKAGRQTTVLQITLYQARDGVKNPLPTSAPWLPADGTAKREVVAFVKNTDFDKLEGLTLKTGFKLEPPPDAMPPSLARMRQGHDPLWCRYPAPAHHRALTQPAFKALEYYSPRAESKAGPTAAAGLLDRWIRFANGERFTGESLGFVADAWPMIVESYRPDPPPTDDETEASQTPFPWDSLFWYPTLNMSLEVKKRLPDQGVEWLFFRVQTKQIRNGRMDMEIVVLDETGDLVALATHVCLVLGLSRNLAGRVKHNETIRSTKDEGGLMKGKSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJB8</accession>
    <name>G4NJB8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_12613</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721077.1">
        <property type="nucleotide sequence ID" value="XM_003721029.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NJB8"/>
    <dbReference type="STRING" id="242507.G4NJB8"/>
    <dbReference type="GeneID" id="5050490"/>
    <dbReference type="KEGG" id="mgr:MGG_12613"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12613"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_31_0_1"/>
    <dbReference type="InParanoid" id="G4NJB8"/>
    <dbReference type="OMA" id="AAGNCFE"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056501">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF29">
        <property type="entry name" value="ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23114">
        <property type="entry name" value="NAD-bd_HRPKS_sdrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="10">
        <location>
            <begin position="18"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="11">
        <location>
            <begin position="966"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="8">
        <location>
            <begin position="966"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="8">
        <location>
            <begin position="1131"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2303"/>
            <end position="2326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2362"/>
            <end position="2383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="2312"/>
            <end position="2323"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="8">
        <location>
            <position position="998"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="8">
        <location>
            <position position="1199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA46334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="2474" mass="268306" checksum="2B100C0C95C19F54" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKK7</accession>
    <name>G4NKK7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_03056</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720625.1">
        <property type="nucleotide sequence ID" value="XM_003720577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKK7"/>
    <dbReference type="SMR" id="G4NKK7"/>
    <dbReference type="MEROPS" id="S53.007"/>
    <dbReference type="GeneID" id="2682609"/>
    <dbReference type="KEGG" id="mgr:MGG_03056"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03056"/>
    <dbReference type="eggNOG" id="ENOG502QZ4I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013783_4_0_1"/>
    <dbReference type="InParanoid" id="G4NKK7"/>
    <dbReference type="OMA" id="CDTMITP"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000015">
        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF19">
        <property type="entry name" value="SERINE PROTEASE AORO, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10250)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
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            <position position="636"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29108"/>
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        <location>
            <position position="654"/>
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        <ligand>
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            <position position="656"/>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
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                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Harding M."/>
                <person name="Kim S."/>
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                <person name="Bohnert H."/>
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                <person name="Butler J."/>
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                <person name="Nicol R."/>
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            <dbReference type="PubMed" id="15846337"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">70-15</strain>
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    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">70-15</strain>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    <sequence length="64" mass="6980" checksum="041C849B89960429" modified="2011-12-14" version="1">MSGRISPASATQLGMAANAPGFIDVATENLKSLHCKYIMKSMFPNEFVLTKKEEEGSSCDRVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH49</accession>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
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                <person name="Butler J."/>
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                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="EHA46497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721240.1">
        <property type="nucleotide sequence ID" value="XM_003721192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH49"/>
    <dbReference type="GeneID" id="12985792"/>
    <dbReference type="KEGG" id="mgr:MGG_18029"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18029"/>
    <dbReference type="HOGENOM" id="CLU_2184499_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ70869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="109" mass="12262" checksum="3446835B22BDB6DF" modified="2011-12-14" version="1">MYKNFSIHQSTVRLHLRPMLLVYRKPHVSDTNAVVLPSEEQGTVGVTVTSDWQKNNTGSLPATITFGTTLKSTNLAMPTVFVQWMVLMGLFAPGTRPCIWTRPKRCRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
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    <name>G5EHP2_PYRO7</name>
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        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGCH7_ch7g151</name>
        <name evidence="9" type="ORF">MGG_10598</name>
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    <organism evidence="8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15</strain>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">70-15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EAQ70744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721344.1">
        <property type="nucleotide sequence ID" value="XM_003721296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHP2"/>
    <dbReference type="SMR" id="G5EHP2"/>
    <dbReference type="STRING" id="242507.G5EHP2"/>
    <dbReference type="GeneID" id="2682211"/>
    <dbReference type="KEGG" id="mgr:MGG_10598"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10598"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_293016_0_0_1"/>
    <dbReference type="OMA" id="MAYNIID"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="535"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="626"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="665"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="672"/>
            <end position="693"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="807"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="328"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <end position="240"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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            <end position="311"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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    </feature>
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        </location>
    </feature>
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    </feature>
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            <begin position="136"/>
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    </feature>
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    <feature type="compositionally biased region" description="Low complexity" evidence="5">
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="983"/>
            <end position="994"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EAQ70744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA46601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1000" mass="108072" checksum="97F126B498360549" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI11</accession>
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        <recommendedName>
            <fullName evidence="10">DUF803 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGCH7_ch7g521</name>
        <name evidence="8" type="ORF">MGG_02771</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15</strain>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">70-15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720978.1">
        <property type="nucleotide sequence ID" value="XM_003720930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI11"/>
    <dbReference type="GeneID" id="2682776"/>
    <dbReference type="KEGG" id="mgr:MGG_02771"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02771"/>
    <dbReference type="eggNOG" id="KOG2922">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011406_1_0_1"/>
    <dbReference type="OMA" id="KPFIVWM"/>
    <dbReference type="OrthoDB" id="2504919at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF86">
        <property type="entry name" value="ADR321CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="428"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="336"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="454"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="473"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="488"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="566"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EAQ71114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA46235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="588" mass="63284" checksum="D5B2A0D161D103E2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-09-13" modified="2026-01-28" version="100" xmlns="https://uniprot.org/uniprot">
    <accession>Q527H0</accession>
    <accession>A4RQ48</accession>
    <accession>G4MPG7</accession>
    <name>CLF1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Pre-mRNA-splicing factor CLF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">CLF1</name>
        <name type="ORF">MGG_05720</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710622.1">
        <property type="nucleotide sequence ID" value="XM_003710574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q527H0"/>
    <dbReference type="SMR" id="Q527H0"/>
    <dbReference type="FunCoup" id="Q527H0">
        <property type="interactions" value="1046"/>
    </dbReference>
    <dbReference type="STRING" id="242507.Q527H0"/>
    <dbReference type="EnsemblFungi" id="MGG_05720T0">
        <property type="protein sequence ID" value="MGG_05720T0"/>
        <property type="gene ID" value="MGG_05720"/>
    </dbReference>
    <dbReference type="GeneID" id="2675972"/>
    <dbReference type="KEGG" id="mgr:MGG_05720"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05720"/>
    <dbReference type="eggNOG" id="KOG1915">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011554_1_0_1"/>
    <dbReference type="InParanoid" id="Q527H0"/>
    <dbReference type="OMA" id="HIKVWIS"/>
    <dbReference type="OrthoDB" id="541719at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000048">
        <property type="entry name" value="Cell cycle control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000306">
        <property type="entry name" value="Cell cycle control protein cwf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000269">
        <property type="entry name" value="Crooked neck pre-mRNA-splicing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
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        <property type="entry name" value="HAT_PRP39_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF3">
        <property type="entry name" value="CROOKED NECK-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23241">
        <property type="entry name" value="HAT_PRP39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0508">mRNA splicing</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0747">Spliceosome</keyword>
    <feature type="chain" id="PRO_0000205747" description="Pre-mRNA-splicing factor CLF1">
        <location>
            <begin position="1"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 1">
        <location>
            <begin position="52"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 2">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 3">
        <location>
            <begin position="120"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 4">
        <location>
            <begin position="154"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 5">
        <location>
            <begin position="187"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 6">
        <location>
            <begin position="220"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 7">
        <location>
            <begin position="260"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 8">
        <location>
            <begin position="304"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 9">
        <location>
            <begin position="338"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 10">
        <location>
            <begin position="382"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 11">
        <location>
            <begin position="420"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 12">
        <location>
            <begin position="453"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 13">
        <location>
            <begin position="487"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 14">
        <location>
            <begin position="523"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 15">
        <location>
            <begin position="574"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 16">
        <location>
            <begin position="617"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="691" mass="82325" checksum="DD231D256AEEEBC2" modified="2005-06-07" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2005-09-13" modified="2026-01-28" version="103" xmlns="https://uniprot.org/uniprot">
    <accession>Q52DF3</accession>
    <accession>A4RHL0</accession>
    <accession>G4MSP9</accession>
    <name>SYF1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Pre-mRNA-splicing factor SYF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">SYF1</name>
        <name type="ORF">MGG_07087</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing and cell cycle progression.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715277.1">
        <property type="nucleotide sequence ID" value="XM_003715229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q52DF3"/>
    <dbReference type="SMR" id="Q52DF3"/>
    <dbReference type="FunCoup" id="Q52DF3">
        <property type="interactions" value="1045"/>
    </dbReference>
    <dbReference type="STRING" id="242507.Q52DF3"/>
    <dbReference type="EnsemblFungi" id="MGG_07087T0">
        <property type="protein sequence ID" value="MGG_07087T0"/>
        <property type="gene ID" value="MGG_07087"/>
    </dbReference>
    <dbReference type="GeneID" id="2682972"/>
    <dbReference type="KEGG" id="mgr:MGG_07087"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07087"/>
    <dbReference type="eggNOG" id="KOG2047">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007736_0_0_1"/>
    <dbReference type="InParanoid" id="Q52DF3"/>
    <dbReference type="OMA" id="IWYNYLR"/>
    <dbReference type="OrthoDB" id="10067343at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000666">
        <property type="entry name" value="DNA repair and transcription protein (Xab2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000023">
        <property type="entry name" value="Pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000720">
        <property type="entry name" value="Pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000038">
        <property type="entry name" value="Putative pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056350">
        <property type="entry name" value="HAT_Syf1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23220">
        <property type="entry name" value="HAT_Syf1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0508">mRNA splicing</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0747">Spliceosome</keyword>
    <feature type="chain" id="PRO_0000205732" description="Pre-mRNA-splicing factor SYF1">
        <location>
            <begin position="1"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 1">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 2">
        <location>
            <begin position="52"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 3">
        <location>
            <begin position="96"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 4">
        <location>
            <begin position="130"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 5">
        <location>
            <begin position="196"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 6">
        <location>
            <begin position="245"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 7">
        <location>
            <begin position="280"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 8">
        <location>
            <begin position="383"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 9">
        <location>
            <begin position="423"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 10">
        <location>
            <begin position="476"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 11">
        <location>
            <begin position="513"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 12">
        <location>
            <begin position="547"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 13">
        <location>
            <begin position="584"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 14">
        <location>
            <begin position="656"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="repeat" description="HAT 15">
        <location>
            <begin position="692"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="832" mass="96280" checksum="E5444124F6AA492E" modified="2007-06-12" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4I8</accession>
    <name>A0A151V4I8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_18117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165176">
        <property type="protein sequence ID" value="KYQ30485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845989.1">
        <property type="nucleotide sequence ID" value="XM_016990578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4I8"/>
    <dbReference type="SMR" id="A0A151V4I8"/>
    <dbReference type="STRING" id="242507.A0A151V4I8"/>
    <dbReference type="GeneID" id="27922201"/>
    <dbReference type="KEGG" id="mgr:MGG_18117"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18117"/>
    <dbReference type="eggNOG" id="ENOG502QR1M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4I8"/>
    <dbReference type="OMA" id="REGDITC"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KYQ30485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="202" mass="21379" checksum="CCBF93CD9246596E" modified="2016-06-08" version="1">MHLAIGATATTDKGSQESPSTGDSSRDTSLNGSDSAVGGPPPSRPEVDVARMNPKVTAAIKQGIADLTEMAPCHHFAEQALNILRHLAKKWNIDDIEVYGKDERAAPTPEAENSVLPVTSSLNFFTPNMSEQDFICDWGNDNGAAGSVSYTTTAHGVDNGLNVAAAASAGRMANPLFWPFPMQGRPMLPSGKLLREAGFEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4K4</accession>
    <name>A0A151V4K4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_18119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165178">
        <property type="protein sequence ID" value="KYQ30507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846011.1">
        <property type="nucleotide sequence ID" value="XM_016990580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4K4"/>
    <dbReference type="GeneID" id="27922203"/>
    <dbReference type="KEGG" id="mgr:MGG_18119"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18119"/>
    <dbReference type="InParanoid" id="A0A151V4K4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KYQ30507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="92" mass="9852" checksum="C70824BFB1C99663" modified="2016-06-08" version="1">MHDDGAFHGPLEPSRKETNPAADGWGLCAMPTHSYVYAPCSLQRSLVTAPRVPGSLTAADFPEAPRSEVPDPTGQESKGGAKNNQWNPPRIL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-05-05" modified="2025-04-09" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>A4RHR8</accession>
    <accession>G4MT61</accession>
    <name>RM04_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>54S ribosomal protein L4, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">MRPL4</name>
        <name type="ORF">MGG_07138</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715333.1">
        <property type="nucleotide sequence ID" value="XM_003715285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RHR8"/>
    <dbReference type="SMR" id="A4RHR8"/>
    <dbReference type="STRING" id="242507.A4RHR8"/>
    <dbReference type="EnsemblFungi" id="MGG_15860T0">
        <property type="protein sequence ID" value="MGG_15860T0"/>
        <property type="gene ID" value="MGG_15860"/>
    </dbReference>
    <dbReference type="KEGG" id="mgr:MGG_15860"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15860"/>
    <dbReference type="eggNOG" id="KOG3331">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063281_1_1_1"/>
    <dbReference type="InParanoid" id="A4RHR8"/>
    <dbReference type="OMA" id="YAHGRAW"/>
    <dbReference type="OrthoDB" id="270763at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038340">
        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010729">
        <property type="entry name" value="Ribosomal_uL29_mit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06984">
        <property type="entry name" value="MRP-L47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0496">Mitochondrion</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0809">Transit peptide</keyword>
    <feature type="transit peptide" description="Mitochondrion" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000372405" description="Large ribosomal subunit protein uL29m">
        <location>
            <begin position="39"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="255"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="302" mass="33609" checksum="7033E68BBD3FC8EC" modified="2007-05-15" version="1" precursor="true">MASSGAARPAASRVLQRCQPFSSSTSCAAPVTTWRTLARPSTAAATAQATTQQLRLLSISMPLQKRRTTRDNNRLRGQSTIHRSGIRRPLSVSEEDIPQPVQDEGVGKMREEDTDPDHGLWGFFYDKQLVPTPKQLSAHGRSWTVQELRGKSWEDLHALWWMCCRERNRIATAIRTRQFIGIKKDNPFDEAEARGRTVNKTMQAIKHVLTERFYAWEDARKLAMEDPEINLSGKGPIYTPSLHFESADTSSYIEEPVADHLETPETSGQEKVGELSPAGAVDPSTILASKTGKPVTDAPRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="93" xmlns="https://uniprot.org/uniprot">
    <accession>A4RLA1</accession>
    <name>A4RLA1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_11252</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714156.1">
        <property type="nucleotide sequence ID" value="XM_003714108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RLA1"/>
    <dbReference type="SMR" id="A4RLA1"/>
    <dbReference type="STRING" id="242507.A4RLA1"/>
    <dbReference type="GeneID" id="2679481"/>
    <dbReference type="KEGG" id="mgr:MGG_11252"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11252"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046889_1_0_1"/>
    <dbReference type="InParanoid" id="A4RLA1"/>
    <dbReference type="OMA" id="QEQVTVC"/>
    <dbReference type="OrthoDB" id="3214149at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000201">
        <property type="entry name" value="C2H2 finger domain protein (Gli3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="171"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="385" mass="42068" checksum="1A3E494B882D3456" modified="2007-05-15" version="1">MAKATSPPDSPLSSMDESDAFNEDGHDTPDPMPPAKRQKLQLDVSTASSAVAGPDPNDPALEGLSPVSSDTSGDIPSSPAHHPHHPHHLRHGDTDDDLHEQVSVCAWGDCDAGDLGNMDRLVEHIHSDHIEGKQKNNYICEWKGCGRNRQLHASGYALKAHMRSHTREKPFYCYLPECDRSFTRSDALAKHMRTVHETEALRPSDPIPKAMQAQTAAGTSTKSGKPLTIVIKTPRSHAAGARDSVLDRDGASPGSENSFQFTELTSEQGFSPKELAMPLPKLHNLLRCTLKWTEEEQQELQREIEAAETAYKNAWLEKEVLLHQVIQNEINWHERRQAVLSGVADVQAKPVAVNGTPAAAATAAADDADSVGGLTEEEMETTMQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKA0</accession>
    <name>G4MKA0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709303.1">
        <property type="nucleotide sequence ID" value="XM_003709255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKA0"/>
    <dbReference type="GeneID" id="12984435"/>
    <dbReference type="KEGG" id="mgr:MGG_16138"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16138"/>
    <dbReference type="HOGENOM" id="CLU_2278007_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKA0"/>
    <dbReference type="OrthoDB" id="10492563at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="102" mass="10973" checksum="0B7BE321346796B7" modified="2011-12-14" version="1">MYIYAVQTTEPIIAGKAPDPGRPADGRTGQKKFDLANPGAHNTTITQVKSHSGATPIQLAERKKAFSAEPQGSEGPEMQMEAERLILLFIYSGSTGYGILRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKX4</accession>
    <name>G4MKX4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Splicing factor 3a subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_05375</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710221.1">
        <property type="nucleotide sequence ID" value="XM_003710173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKX4"/>
    <dbReference type="SMR" id="G4MKX4"/>
    <dbReference type="FunCoup" id="G4MKX4">
        <property type="interactions" value="413"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MKX4"/>
    <dbReference type="GeneID" id="2675831"/>
    <dbReference type="KEGG" id="mgr:MGG_05375"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05375"/>
    <dbReference type="eggNOG" id="KOG0227">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050757_1_0_1"/>
    <dbReference type="InParanoid" id="G4MKX4"/>
    <dbReference type="OMA" id="EFWIQIM"/>
    <dbReference type="OrthoDB" id="10250970at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.2690:FF:000002">
        <property type="entry name" value="Splicing factor 3a subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052092">
        <property type="entry name" value="SF3A2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031781">
        <property type="entry name" value="SF3A2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205:SF0">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16835">
        <property type="entry name" value="SF3A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="10">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="71"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA57609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="247" mass="27772" checksum="5E428DF91B9E4F99" modified="2011-12-14" version="1">MDYQNRAGSKFGGGGVASHSATNADRRERLRKLALEHIDLDKDPYIFKNHLGAFECRLCLTVHQNDGSYLAHTQGRKHQTNLARRAAQEKRDGRDKNIDPQTGLPVGVVGAGFSALGLGGGARKNAVKIGRPGYKITKIRDPVTRAEGLLFQLQFPDISPGTVPKWQVMSAFSQRVEEPDRNYQYLLVAAEPYETCGFKVPARELDKREGRMFEYWDPDAKEYWVQVMFMTEREERFNAAPGLGARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLB0</accession>
    <name>G4MLB0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710252.1">
        <property type="nucleotide sequence ID" value="XM_003710204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLB0"/>
    <dbReference type="GeneID" id="5051456"/>
    <dbReference type="KEGG" id="mgr:MGG_13043"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13043"/>
    <dbReference type="HOGENOM" id="CLU_2527909_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLB0"/>
    <dbReference type="OMA" id="IRQKSGH"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="84" mass="9162" checksum="EF8337FA16FF1DCE" modified="2011-12-14" version="1">MPKSPIRQKSGHLRPGRSVGPPRTINYTLELRGASIPAPHPETTSRPRLGAQLAPVPFKRWGSAPRGARWTLASYAVPKSPELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLQ1</accession>
    <name>G4MLQ1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trans-sialidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_13058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710291.1">
        <property type="nucleotide sequence ID" value="XM_003710243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLQ1"/>
    <dbReference type="GeneID" id="5051469"/>
    <dbReference type="KEGG" id="mgr:MGG_13058"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13058"/>
    <dbReference type="eggNOG" id="ENOG502RXA3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010837_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLQ1"/>
    <dbReference type="OMA" id="NNAFMKT"/>
    <dbReference type="OrthoDB" id="5421842at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="827" mass="91796" checksum="3C146AB46259EBB6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMP6</accession>
    <name>G4MMP6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710430.1">
        <property type="nucleotide sequence ID" value="XM_003710382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMP6"/>
    <dbReference type="SMR" id="G4MMP6"/>
    <dbReference type="STRING" id="242507.G4MMP6"/>
    <dbReference type="GeneID" id="12986334"/>
    <dbReference type="KEGG" id="mgr:MGG_16403"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16403"/>
    <dbReference type="eggNOG" id="ENOG502T5JI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_824048_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMP6"/>
    <dbReference type="OMA" id="INMNDAW"/>
    <dbReference type="OrthoDB" id="5239816at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="337" mass="38416" checksum="123C19AF2DB535BE" modified="2011-12-14" version="1">MNRASSTNPRSGKSAFPPPLNLNKRSPPATASNATTRAGEKPTKDNAKPKSDSKTKDQDKMEDDYVDVTPASPASAKPAPKASTQYSNNFSKADARFSTTAQSSYGAFDPLDYAASEAAPPLPTGENGEASEEVRRRRLEEKQRREEEWEEEQAQRKRERERLAQERRQREIQEEEERRRREWAEEEERRRRREEEEEFDEEIPRRQSPPRQEQYQRRPSGADRRNSYARHSFHRQNDSRDYRRYNSNSNSNSNNNSGNEEENARGDPRRERININMNDAWQSWTSMGGGRDDRGGFGIGGTPGFGLFGGQRAGFGPVGNLPVTQLPGLGGFRMFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMY0</accession>
    <name>G4MMY0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_16202</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709614.1">
        <property type="nucleotide sequence ID" value="XM_003709566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMY0"/>
    <dbReference type="SMR" id="G4MMY0"/>
    <dbReference type="STRING" id="242507.G4MMY0"/>
    <dbReference type="GeneID" id="12985221"/>
    <dbReference type="KEGG" id="mgr:MGG_16202"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16202"/>
    <dbReference type="eggNOG" id="KOG2431">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003818_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMY0"/>
    <dbReference type="OMA" id="VWGTNEF"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000037">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF49">
        <property type="entry name" value="ALPHA-1,2-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="505"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="591"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="390"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA57002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="599" mass="67325" checksum="F341BE62D0D0F668" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN43</accession>
    <name>G4MN43_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_05592</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710469.1">
        <property type="nucleotide sequence ID" value="XM_003710421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN43"/>
    <dbReference type="SMR" id="G4MN43"/>
    <dbReference type="GeneID" id="2675917"/>
    <dbReference type="KEGG" id="mgr:MGG_05592"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05592"/>
    <dbReference type="eggNOG" id="ENOG502QPXZ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_1_1_1"/>
    <dbReference type="InParanoid" id="G4MN43"/>
    <dbReference type="OMA" id="CAYENAT"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005132164" description="Carboxylic ester hydrolase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA57857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="541" mass="58500" checksum="1F11311E133DE679" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNE7</accession>
    <name>G4MNE7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709673.1">
        <property type="nucleotide sequence ID" value="XM_003709625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNE7"/>
    <dbReference type="GeneID" id="2685107"/>
    <dbReference type="KEGG" id="mgr:MGG_06934"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06934"/>
    <dbReference type="eggNOG" id="ENOG502S0NF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033551_1_0_1"/>
    <dbReference type="InParanoid" id="G4MNE7"/>
    <dbReference type="OMA" id="NHAWLAL"/>
    <dbReference type="OrthoDB" id="5552418at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="404" mass="43501" checksum="8084E2F0BCA9A59A" modified="2011-12-14" version="1">MDDNNIRRRQNEQPVHPASNQRYSQQSIQDPAQQRRYATSSSADSRYRAAPLNSSPAGTARGMGGSAGYSGYYQDSTAGAFPTGTAMPQSSMSSYHQSTTDYGQDGRQTQNFTGYNPANMMYNVQSASAQNPGVYDTSQQSFQRQPTAALQMMAADVASANPYFSGDASNTGTASMQAQGASSNTSSAVYQNPADRNALLGYSGNMASMSGLASQAAGAAAAAAAAPAAATADVSLDEQEYPATSGLDEAYASYQTALKEIFQNVTNGILQAASESLLNVSDWLLSHVTELGLTSDDQTLYNDRIKLWNDFNHAWLSLLQKQKELMESGQQLQRNQTLINKDGLEKMAKELLRLCDQIERHGLVDYQYGVWEEQIIAILEECADLYGSGDESNGASATSASRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2024-07-24" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP74</accession>
    <name>G4MP74_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16050</name>
        <name evidence="2" type="ORF">MGG_16597</name>
        <name evidence="1" type="ORF">MGG_17867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708945.1">
        <property type="nucleotide sequence ID" value="XM_003708897.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711230.1">
        <property type="nucleotide sequence ID" value="XM_003711182.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720555.1">
        <property type="nucleotide sequence ID" value="XM_003720507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP74"/>
    <dbReference type="GeneID" id="12984725"/>
    <dbReference type="GeneID" id="12985721"/>
    <dbReference type="GeneID" id="12986981"/>
    <dbReference type="KEGG" id="mgr:MGG_16050"/>
    <dbReference type="KEGG" id="mgr:MGG_16597"/>
    <dbReference type="KEGG" id="mgr:MGG_17867"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16050"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16597"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17867"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA45812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="80" mass="9455" checksum="C68636BC6C798F18" modified="2011-12-14" version="1" fragment="single">SPLLFVYSQFYLVPKWSGEWWNSVTLLMQECNLKVSEWVFRKFIRGTGTFSGVRTPISMSEMHFYLLFSAFSTGYLPRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPM0</accession>
    <name>G4MPM0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708981.1">
        <property type="nucleotide sequence ID" value="XM_003708933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPM0"/>
    <dbReference type="SMR" id="G4MPM0"/>
    <dbReference type="CAZy" id="GT1">
        <property type="family name" value="Glycosyltransferase Family 1"/>
    </dbReference>
    <dbReference type="GeneID" id="2681287"/>
    <dbReference type="KEGG" id="mgr:MGG_02217"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02217"/>
    <dbReference type="eggNOG" id="KOG1192">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000537_4_1_1"/>
    <dbReference type="InParanoid" id="G4MPM0"/>
    <dbReference type="OMA" id="PGNAQMA"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015:SF22">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21015">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="1">
        <location>
            <begin position="321"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="468" mass="51165" checksum="816D708754F9D37E" modified="2011-12-14" version="1">MTVNHNVPAQVDGMKHPYLVFAARPEHGHTYPILQIARDMIRRGFEATILTGEQYGEDIIKMGARPVTLPHYDPTPEALGELAKVTSKLQTLAWGLRHIVAPQMPIWYGTLKETLETLRLERPGQQFIIMSDLAFTGQQPLVRGAPLPKGFSVRPPVIHINVVPLAMPSIDTGPFGLGLPPDSSESGRARNKLLNAIYYGPDGPYGPFGAEHIRLLKSLGATDIPSTVEAWGYTTSFPDITLQVCSPSLEFPRSDLPDNVHFVGCLPRKPIGPDYEYPQWLKDIVSPTDGSTRKKRIIGVAQGTIAVDYTDLIIPTIQGLANDDDVVVIALLGKKGATLPERVTVPANARVVDYMPYEVVLNHADVWVANAGYGGFTQGVMHGVPMVLAGDTQDKPDIAMVGEWSGVACNLRTGTPTPEQVAKGVREILSNDSYKARVVEVQKENEAMNCLDAVEKHIWDIFAKMGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQE5</accession>
    <name>G4MQE5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_10893</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710743.1">
        <property type="nucleotide sequence ID" value="XM_003710695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQE5"/>
    <dbReference type="FunCoup" id="G4MQE5">
        <property type="interactions" value="152"/>
    </dbReference>
    <dbReference type="GeneID" id="2677040"/>
    <dbReference type="KEGG" id="mgr:MGG_10893"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10893"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="InParanoid" id="G4MQE5"/>
    <dbReference type="OMA" id="IVPMVMW"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF91">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="69"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA58131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="515" mass="56760" checksum="69D7EF492BC82141" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQH0</accession>
    <name>G4MQH0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709072.1">
        <property type="nucleotide sequence ID" value="XM_003709024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQH0"/>
    <dbReference type="STRING" id="242507.G4MQH0"/>
    <dbReference type="GeneID" id="2681403"/>
    <dbReference type="KEGG" id="mgr:MGG_02306"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02306"/>
    <dbReference type="eggNOG" id="ENOG502SPZY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083329_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQH0"/>
    <dbReference type="OMA" id="INFMEDL"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046503">
        <property type="term" value="P:glycerolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="22"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="275" mass="28645" checksum="C2CCDCDD92198C48" modified="2011-12-14" version="1">MVPSTLAVKGAILAYSCLGSGPLLVTVPGANGDAAIFDLAVPHLANNFTVCSYDRRGYSRSVYTEPNDLTMPVRLQTDADDVAALIDHLSPGEPALVFGTSSGAIVSLDLLSRHPEAVSFLVAHEPPLTRTLGEAGAQIQAVFQSAEDTFFSEGIHAAVQVFLGPVVASDPESVAAHDALDSPAHASNAALFFAHEINHYTAYSVDTPALQASRDKLVFDNGDDSTPPATTMTDNLAQSVGVAVEHTPGGHLGYVSKPVEFAAALAEIFAAHGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQM0</accession>
    <name>G4MQM0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709122.1">
        <property type="nucleotide sequence ID" value="XM_003709074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQM0"/>
    <dbReference type="GeneID" id="12984363"/>
    <dbReference type="KEGG" id="mgr:MGG_16102"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16102"/>
    <dbReference type="HOGENOM" id="CLU_2740535_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQM0"/>
    <dbReference type="OMA" id="NNHVRIR"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="83" mass="9262" checksum="30C6B80C3D0C8297" modified="2011-12-14" version="1">MRKRHESGGRPRGDTRDKLKTLTAYVDQALEGGNNHVRIRPLDLPSESREDQAPRPTLRITTRLHTEPGIGQGSTTSGFKRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="3">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
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    <gene>
        <name evidence="3" type="ORF">MGG_04756</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710786.1">
        <property type="nucleotide sequence ID" value="XM_003710738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQU3"/>
    <dbReference type="SMR" id="G4MQU3"/>
    <dbReference type="STRING" id="242507.G4MQU3"/>
    <dbReference type="GeneID" id="2677958"/>
    <dbReference type="KEGG" id="mgr:MGG_04756"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04756"/>
    <dbReference type="eggNOG" id="KOG1211">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_14_1_1"/>
    <dbReference type="InParanoid" id="G4MQU3"/>
    <dbReference type="OMA" id="HANDSWA"/>
    <dbReference type="OrthoDB" id="566138at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
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        <property type="entry name" value="AMIDASE"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR42678:SF34">
        <property type="entry name" value="OS04G0183300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465503" evidence="1">
        <location>
            <begin position="20"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="53"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="555" mass="60170" checksum="AD64479D11EBECD0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR12</accession>
    <name>G4MR12_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02383</name>
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    <organism evidence="3 4">
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709159.1">
        <property type="nucleotide sequence ID" value="XM_003709111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR12"/>
    <dbReference type="STRING" id="242507.G4MR12"/>
    <dbReference type="GeneID" id="2681480"/>
    <dbReference type="KEGG" id="mgr:MGG_02383"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02383"/>
    <dbReference type="HOGENOM" id="CLU_075359_0_0_1"/>
    <dbReference type="InParanoid" id="G4MR12"/>
    <dbReference type="OMA" id="CMHACAM"/>
    <dbReference type="OrthoDB" id="5230381at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="30762" checksum="D5ACD7284235E712" modified="2011-12-14" version="1">MSIHDGPELVLAHGMEYTCEAQDSLKYPAHDQQYMQPHAVSPDPKSSYTITSSHCRKSDLPFSMPTWVFASLAVLLGALIGGSIVGGVLGSMLVNRPRHSDSSTANDPIVTSPTPASPAPASPTQVSPSPASPTGPAPQPEAPFANYMAPPRSAILNLSMPCSGPLSMHQQRFRSFNDRRFDLQCYINNFGLGTNGYIIADITAIMAYRWQDCFDACASHNKLQSGLPSHLVCRSAVYTINVTLPAITLQGGNCFLKNSSRHANNPGEGNGLNVFSADLELMPSEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRE2</accession>
    <name>G4MRE2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pirin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_02400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709181.1">
        <property type="nucleotide sequence ID" value="XM_003709133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRE2"/>
    <dbReference type="SMR" id="G4MRE2"/>
    <dbReference type="STRING" id="242507.G4MRE2"/>
    <dbReference type="GeneID" id="2681497"/>
    <dbReference type="KEGG" id="mgr:MGG_02400"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02400"/>
    <dbReference type="eggNOG" id="ENOG502QQ5A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045717_0_2_1"/>
    <dbReference type="InParanoid" id="G4MRE2"/>
    <dbReference type="OMA" id="TPWHPHR"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="3">
        <location>
            <begin position="97"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="4">
        <location>
            <begin position="252"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA56569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="380" mass="41766" checksum="3B47A9EA499CA86D" modified="2011-12-14" version="1">MKSISTILIPIIVGLCSVFLFRDRIDDLTATLKKYYNDNYISTTATHEPVNALPRTTTATDQQPEEQEPHLYATEMSVPRTIRKVFEAIEQAEGAGARVRRSIGTPALRQFSPFLMLDHFSIKPGAGFPDHPHRGQETITYLLTGAVDHEDFAGNKGTIEAGDLQFMTAGRGIMHAEMPRQNPDGSANVGLQLWVDLPTHLKSCEPRYRDLRASEIPRADVDEGKVSVKIISGQSHGVDSVKDLAYTPVWILDVTIQPGGKISQPLPEGWNAFAYTLDGGDVILRDGAGTGARTVPQYHMVVFEPKGEIVVAEVDAGADQAARFVLVAGTPLDQPVVQHGPFVVNSKEEIYKAIFDFQTHSNGFERAKGWESEIGKSMRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRS2</accession>
    <name>G4MRS2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CorA-like transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_04594</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710899.1">
        <property type="nucleotide sequence ID" value="XM_003710851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRS2"/>
    <dbReference type="GeneID" id="2677980"/>
    <dbReference type="KEGG" id="mgr:MGG_04594"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04594"/>
    <dbReference type="eggNOG" id="ENOG502SAMN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029947_2_0_1"/>
    <dbReference type="InParanoid" id="G4MRS2"/>
    <dbReference type="OMA" id="GVYHHRR"/>
    <dbReference type="OrthoDB" id="5392974at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058257">
        <property type="entry name" value="CorA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26616">
        <property type="entry name" value="CorA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="CorA-like transporter" evidence="6">
        <location>
            <begin position="116"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA58287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="517" mass="57316" checksum="634F55794F493805" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRY5</accession>
    <name>G4MRY5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709266.1">
        <property type="nucleotide sequence ID" value="XM_003709218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRY5"/>
    <dbReference type="GeneID" id="2681569"/>
    <dbReference type="KEGG" id="mgr:MGG_02472"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02472"/>
    <dbReference type="eggNOG" id="ENOG502RJR0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088991_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRY5"/>
    <dbReference type="OMA" id="REFQREW"/>
    <dbReference type="OrthoDB" id="5305418at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035186">
        <property type="entry name" value="DUF5308"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17233">
        <property type="entry name" value="DUF5308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="270" mass="28323" checksum="94FEB066BCDAEBE6" modified="2011-12-14" version="1">MASIPQLHPQLSLHLADRSLTPLISTSRTLAAGGGSSPEEQQKKQDALASLASTALTIHDAALHFGLGRPQRVLADYGGPVMIQTFLDPAALRDEHHSTLPLAATPNAAAAAETPVGGGGVGATHLMPHRPLPHRGLSASSIRSAFSRPTSSNTTGQRLQMDGGDGFRMNGSSPAPQADRVSYYGGPDLSRPAAAKNAHAADDDDERDHHDGNDDGGSMDSHKEDDDADASPMLVGIVLSASAEEASDSRRATARLEKIGREIQRRWSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSC8</accession>
    <name>G4MSC8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713547.1">
        <property type="nucleotide sequence ID" value="XM_003713499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSC8"/>
    <dbReference type="GeneID" id="2678121"/>
    <dbReference type="KEGG" id="mgr:MGG_04451"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04451"/>
    <dbReference type="HOGENOM" id="CLU_1796848_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSC8"/>
    <dbReference type="OrthoDB" id="10508209at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465552" evidence="1">
        <location>
            <begin position="20"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="144" mass="15345" checksum="DD21F83B34A0276B" modified="2011-12-14" version="1">MRYLTISLTLALCVLSTAAAPTPSSPRGATHVGKLEAYNKMQPRGDPTAGLSSRAPKAGDHIADFDQLPGGEYRGQDEAKAAKLEARGGPGLEYRVGDPVASALLRDTSLQTSRSGNMIRFWRPEGVTYQGPQAKMHTASFMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSL8</accession>
    <name>G4MSL8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G2/mitotic-specific cyclin-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_07065</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715246.1">
        <property type="nucleotide sequence ID" value="XM_003715198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSL8"/>
    <dbReference type="SMR" id="G4MSL8"/>
    <dbReference type="FunCoup" id="G4MSL8">
        <property type="interactions" value="1738"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSL8"/>
    <dbReference type="GeneID" id="2682950"/>
    <dbReference type="KEGG" id="mgr:MGG_07065"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07065"/>
    <dbReference type="eggNOG" id="KOG0653">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020695_9_1_1"/>
    <dbReference type="InParanoid" id="G4MSL8"/>
    <dbReference type="OMA" id="TMMIECC"/>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20512">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000001">
        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="401"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="494"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="498"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="283"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA55439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="657" mass="73695" checksum="32845EFCC74E5F6D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSN3</accession>
    <name>G4MSN3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATPase family AAA domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07075</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA55454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715261.1">
        <property type="nucleotide sequence ID" value="XM_003715213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSN3"/>
    <dbReference type="SMR" id="G4MSN3"/>
    <dbReference type="FunCoup" id="G4MSN3">
        <property type="interactions" value="607"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSN3"/>
    <dbReference type="GeneID" id="2682960"/>
    <dbReference type="KEGG" id="mgr:MGG_07075"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07075"/>
    <dbReference type="eggNOG" id="KOG0737">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000688_21_14_1"/>
    <dbReference type="InParanoid" id="G4MSN3"/>
    <dbReference type="OMA" id="CRNAAMR"/>
    <dbReference type="OrthoDB" id="10254455at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140567">
        <property type="term" value="F:membrane protein dislocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140570">
        <property type="term" value="P:extraction of mislocalized protein from mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034214">
        <property type="term" value="P:protein hexamerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006626">
        <property type="term" value="P:protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000538">
        <property type="entry name" value="ATPase family AAA domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051701">
        <property type="entry name" value="Mito_OM_Translocase_MSP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644:SF3">
        <property type="entry name" value="FI08533P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="150"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="348"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="424" mass="46527" checksum="82B918855F6E29DC" modified="2011-12-14" version="1">MADRKRATDYFIDIVVFAGMTATLYLLTKNILSSLSSTLGDPDKEKHEQARLRAKANLQRLRKIQNGDGTANGEAQDGEGGQRNGPAVEELQLNEYENMIAMDVVAPEDINVGFDAIGGLEDIIEEVKESVIYPLTMPHLYSHAAPLLSAPSGVLLYGPPGCGKTMLAKAVAHESGASFINLHISTLTEKWYGDSNKLVRAVFSLARKLQPAIIFIDEIDAVLGTRRSGEHEASGMVKAEFMTLWDGLTSANASGVPSRIMVLGATNRINDIDEAILRRMPKKFPVPLPGTEQRRRILELILGETKRDPEHFDLEYIAAVTAGMSGSEIKDACRDAAMSPMREFIRTQRAAGTPMASIDPTQVRGIRTDDFFSRKGAGPRVRSMGENKKSTAKQNSTTEKHAERAEDSEYEDVDEEHTRPVSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MST3</accession>
    <name>G4MST3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713594.1">
        <property type="nucleotide sequence ID" value="XM_003713546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MST3"/>
    <dbReference type="SMR" id="G4MST3"/>
    <dbReference type="STRING" id="242507.G4MST3"/>
    <dbReference type="GeneID" id="2677765"/>
    <dbReference type="KEGG" id="mgr:MGG_04543"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04543"/>
    <dbReference type="eggNOG" id="ENOG502SG5H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050102_1_0_1"/>
    <dbReference type="InParanoid" id="G4MST3"/>
    <dbReference type="OMA" id="ENEWTTV"/>
    <dbReference type="OrthoDB" id="4207724at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="449" mass="48860" checksum="F0ED1CEC01E6630D" modified="2011-12-14" version="1">MGAANSTLVGWTIVLAIAGFVGWREWDAKQKRLLQKTAGQRSREEHRNATQSRRDTKKDEKEHSKVKRQRVADSQPEKPKEKPKEKETVAAPIEKEQPKSSKKKSNTYSSDDDAASNREFARQLSSVKEGTKFTAKSKDDVRQKSVKQSRADEAKRQVAKPVVEEPKAASPPSSTAGIDADDDQSSAASPVVAPTANAGDVSDMLEKPTSGPSVLRLTDTEEKKKTQKAKAPQPVETKKQRQNRKKVEAAKAMREEAEAERKILEQAQRRTAREAEGRAAKDGSGFMAAQAKGTVWTGGKDVNDSNNGVVPVQPLDTSEPTATQPKTQQKQAGAAKKEAKGDKWVSSLPSEEEQIKMIEDEESWSTVPTKASRKSKKNKESAVDSMDEGAASETKPAPAAAAPAPTPVQPAKKPQVENQRPVKTFSQTSSFAALNADGAADLEEEEWDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSU9</accession>
    <name>G4MSU9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Riboflavin synthase</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_04586</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713610.1">
        <property type="nucleotide sequence ID" value="XM_003713562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSU9"/>
    <dbReference type="SMR" id="G4MSU9"/>
    <dbReference type="FunCoup" id="G4MSU9">
        <property type="interactions" value="171"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSU9"/>
    <dbReference type="GeneID" id="2678113"/>
    <dbReference type="KEGG" id="mgr:MGG_04586"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04586"/>
    <dbReference type="eggNOG" id="KOG3310">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034388_1_1_1"/>
    <dbReference type="InParanoid" id="G4MSU9"/>
    <dbReference type="OMA" id="IGGHAMS"/>
    <dbReference type="OrthoDB" id="10258924at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000004">
        <property type="entry name" value="Riboflavin synthase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000006">
        <property type="entry name" value="Riboflavin synthase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006767">
        <property type="entry name" value="PRK09289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098:SF0">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lumazine-binding" evidence="10">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="9">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="9">
        <location>
            <begin position="102"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="10">
        <location>
            <begin position="102"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA53803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="214" mass="22839" checksum="6701B569BDAB86E2" modified="2011-12-14" version="1">MFTGIVEEIGVVAELNPHDATGGTSLTISLPTGSSLLSDCHDGDSIAVNGVCLTVTSFTPTQFTVGVAPETLRVTDLGDLVKDSRVNLERAVRADTRMGGHFVQGHVDTTATIADKQADGNAVTMRFKPREGSDVLKYIVRKGYVALDGTSLTVTKVDDAAGWWEVMLIVYTQERVVLAQKNVGDTVNVEVDVLAKYAEKSMAGYLSSLNKSDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSV4</accession>
    <name>G4MSV4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA replication regulator Sld3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713615.1">
        <property type="nucleotide sequence ID" value="XM_003713567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSV4"/>
    <dbReference type="SMR" id="G4MSV4"/>
    <dbReference type="STRING" id="242507.G4MSV4"/>
    <dbReference type="GeneID" id="5051337"/>
    <dbReference type="KEGG" id="mgr:MGG_04600"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04600"/>
    <dbReference type="eggNOG" id="ENOG502S01X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006240_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSV4"/>
    <dbReference type="OMA" id="IYEQLGW"/>
    <dbReference type="OrthoDB" id="6593433at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013948">
        <property type="entry name" value="DNA_replication_reg_Sld3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042511">
        <property type="entry name" value="Sld3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28067">
        <property type="entry name" value="DNA REPLICATION REGULATOR SLD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28067:SF1">
        <property type="entry name" value="DNA REPLICATION REGULATOR SLD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08639">
        <property type="entry name" value="Sld3_STD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication regulator Sld3 C-terminal" evidence="2">
        <location>
            <begin position="325"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="680"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="850"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1030"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="614"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1065" mass="116579" checksum="7EEE7BB64CFDE050" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU27</accession>
    <name>G4MU27_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Conidial yellow pigment biosynthesis polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07219</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715434.1">
        <property type="nucleotide sequence ID" value="XM_003715386.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MU27"/>
    <dbReference type="GeneID" id="2683107"/>
    <dbReference type="KEGG" id="mgr:MGG_07219"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07219"/>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_6_0_1"/>
    <dbReference type="InParanoid" id="G4MU27"/>
    <dbReference type="OMA" id="YCRGDGC"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.366.10:FF:000002">
        <property type="entry name" value="Probable polyketide synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000011">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.110:FF:000001">
        <property type="entry name" value="Sterigmatocystin biosynthesis polyketide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049551">
        <property type="entry name" value="PKS_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030918">
        <property type="entry name" value="PT_fungal_PKS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04532">
        <property type="entry name" value="PT_fungal_PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF37">
        <property type="entry name" value="SI:DKEY-61P9.11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22621">
        <property type="entry name" value="CurL-like_PKS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01294">
        <property type="entry name" value="PKS_PP_betabranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="387"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="1304"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1663"/>
            <end position="1740"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1790"/>
            <end position="1867"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1304"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1463"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1632"/>
            <end position="1655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1743"/>
            <end position="1792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1870"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1637"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1746"/>
            <end position="1759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1870"/>
            <end position="1882"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="1336"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="2181" mass="236512" checksum="1B0C748F21FDA2A4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU46</accession>
    <name>G4MU46_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07234</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3 6"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715453.1">
        <property type="nucleotide sequence ID" value="XM_003715405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU46"/>
    <dbReference type="SMR" id="G4MU46"/>
    <dbReference type="FunCoup" id="G4MU46">
        <property type="interactions" value="543"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MU46"/>
    <dbReference type="GeneID" id="2683122"/>
    <dbReference type="KEGG" id="mgr:MGG_07234"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07234"/>
    <dbReference type="eggNOG" id="KOG0549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013615_8_1_1"/>
    <dbReference type="InParanoid" id="G4MU46"/>
    <dbReference type="OMA" id="DKINVHY"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044609">
        <property type="entry name" value="FKBP2/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45779:SF7">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465332" description="peptidylprolyl isomerase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="8">
        <location>
            <begin position="40"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="185" mass="19562" checksum="7E03E8E3DF158C25" modified="2011-12-14" version="1">MKLLVSLSLLASAAVTVLAADELGIEVTQAVNCERKTKNGDMVHMHYKGTLQSTGDKFDASYDRGTPLAFPLGTGRVIKGWDQGLLDMCIGEKRTLTIPPSLGYGDGGIGPIPGGATLIFETELVSIDGVETPEKIDYVSKAEEAASKATEKVAEKVADKIKEAAEVVKTVVADSDDAGQEHNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUJ6</accession>
    <name>G4MUJ6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial ribosomal small subunit component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715495.1">
        <property type="nucleotide sequence ID" value="XM_003715447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUJ6"/>
    <dbReference type="SMR" id="G4MUJ6"/>
    <dbReference type="FunCoup" id="G4MUJ6">
        <property type="interactions" value="112"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MUJ6"/>
    <dbReference type="GeneID" id="2683017"/>
    <dbReference type="KEGG" id="mgr:MGG_07271"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07271"/>
    <dbReference type="eggNOG" id="KOG3933">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051514_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUJ6"/>
    <dbReference type="OMA" id="IAGMELY"/>
    <dbReference type="OrthoDB" id="283424at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019349">
        <property type="entry name" value="Ribosomal_mS35_mit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039848">
        <property type="entry name" value="Ribosomal_mS35_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10213">
        <property type="entry name" value="MRP-S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS35 mitochondrial conserved" evidence="1">
        <location>
            <begin position="195"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="389" mass="43706" checksum="2A61CD1DFDEBA835" modified="2011-12-14" version="1">MMSAAYPLRSCVRAGSKTFSSLQVRSSTATGKHVSADSLRCTTTTTTNLAAGRRWASGKSGKQADERTIAGMELYDGKRLQHMIDDLFEKAGTKSQKAVISDKANALADSQLATLSSASNTAERIPKKYRTGQYEFWNEGEDDPDYISEEVLDEEFNEDDILSGAHGKLEEHREMREYARLAIYDMPLLSKFAKPFEPPTRATPLRWRYTSYLGEFHPAEKKVVVEFCPEDFGLTEVQVSKLKKLAGPRYNPEKGTIKMSCENFEHAAQNKRYLGDLAMKLIAEAKDPKDTFEDIPLDTRHHPIKSKPKFPMEWRMTEDRKAQLVQLRHEAYLLDQAKKSKGALIDGSEVIKKSLEAPTEDAVTSAEEKLLQFVRAETSKSGGNRPAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV56</accession>
    <name>G4MV56_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713878.1">
        <property type="nucleotide sequence ID" value="XM_003713830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV56"/>
    <dbReference type="STRING" id="242507.G4MV56"/>
    <dbReference type="GeneID" id="2679841"/>
    <dbReference type="KEGG" id="mgr:MGG_08855"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08855"/>
    <dbReference type="eggNOG" id="ENOG502S8T0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003878_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV56"/>
    <dbReference type="OMA" id="AHPHQWS"/>
    <dbReference type="OrthoDB" id="4153178at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="923"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="992"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="744"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="799"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="647"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="754"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="802"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1020" mass="109624" checksum="CB211C18A75515A5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVS4</accession>
    <name>G4MVS4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CMGC/RCK/MAK protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_15325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714797.1">
        <property type="nucleotide sequence ID" value="XM_003714749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVS4"/>
    <dbReference type="SMR" id="G4MVS4"/>
    <dbReference type="STRING" id="242507.G4MVS4"/>
    <dbReference type="GeneID" id="12985410"/>
    <dbReference type="KEGG" id="mgr:MGG_15325"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15325"/>
    <dbReference type="eggNOG" id="KOG0661">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_011172_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVS4"/>
    <dbReference type="OMA" id="GNWYNKA"/>
    <dbReference type="OrthoDB" id="2158884at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
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        <property type="project" value="UniProtKB-ARBA"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Meiosis induction protein kinase"/>
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        <property type="entry name" value="Serine threonine-protein kinase mak"/>
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    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
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    </dbReference>
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    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
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        <property type="entry name" value="Protein_kinase_ATP_BS"/>
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    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
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    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
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    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="7" id="KW-0808">Transferase</keyword>
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        <location>
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            <end position="352"/>
        </location>
    </feature>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="531"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="702"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="382"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="724"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="808" mass="88119" checksum="0190CE1EBE3EEFE2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWG9</accession>
    <name>G4MWG9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">xylan 1,4-beta-xylosidase</fullName>
            <ecNumber evidence="11">3.2.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_08985</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Hydrolysis of (1-&gt;4)-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini.</text>
            <dbReference type="EC" id="3.2.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycan degradation; xylan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.37" evidence="11"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714024.1">
        <property type="nucleotide sequence ID" value="XM_003713976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWG9"/>
    <dbReference type="SMR" id="G4MWG9"/>
    <dbReference type="STRING" id="242507.G4MWG9"/>
    <dbReference type="GeneID" id="2679970"/>
    <dbReference type="KEGG" id="mgr:MGG_08985"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08985"/>
    <dbReference type="eggNOG" id="ENOG502QQ55">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_5_3_1"/>
    <dbReference type="InParanoid" id="G4MWG9"/>
    <dbReference type="OMA" id="KVYTKVC"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="UniPathway" id="UPA00114"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="14">
        <location>
            <begin position="753"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA54217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="847" mass="92158" checksum="2C4244680274837A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXR9</accession>
    <name>G4MXR9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Autophagy-related protein 28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715013.1">
        <property type="nucleotide sequence ID" value="XM_003714965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXR9"/>
    <dbReference type="SMR" id="G4MXR9"/>
    <dbReference type="STRING" id="242507.G4MXR9"/>
    <dbReference type="GeneID" id="2678265"/>
    <dbReference type="KEGG" id="mgr:MGG_08061"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08061"/>
    <dbReference type="eggNOG" id="ENOG502SANW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015530_1_0_1"/>
    <dbReference type="InParanoid" id="G4MXR9"/>
    <dbReference type="OMA" id="HWNLLIC"/>
    <dbReference type="OrthoDB" id="5342758at2759"/>
    <dbReference type="PHI-base" id="PHI:2089"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="285"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="559"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="601"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="645" mass="70631" checksum="B0C20B8601DFE515" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY78</accession>
    <name>G4MY78_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DOPA 4,5-dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714216.1">
        <property type="nucleotide sequence ID" value="XM_003714168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY78"/>
    <dbReference type="SMR" id="G4MY78"/>
    <dbReference type="STRING" id="242507.G4MY78"/>
    <dbReference type="GeneID" id="2679574"/>
    <dbReference type="KEGG" id="mgr:MGG_01293"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01293"/>
    <dbReference type="eggNOG" id="ENOG502S93P">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090062_0_1_1"/>
    <dbReference type="InParanoid" id="G4MY78"/>
    <dbReference type="OMA" id="DIHIYYF"/>
    <dbReference type="OrthoDB" id="9970095at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1240">
        <property type="entry name" value="DOPA-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023389">
        <property type="entry name" value="DOPA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014980">
        <property type="entry name" value="DOPA_dioxygen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36423:SF2">
        <property type="entry name" value="AFR070WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08883">
        <property type="entry name" value="DOPA_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143410">
        <property type="entry name" value="DOPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21868" checksum="82B13F6D27D9147B" modified="2011-12-14" version="1">MACRYYPATASYPSPLKGFENLPPLSEEKDGDGKSLRNEQTGVRSKAYEEFVDPLDRGKRGGFDVHIYYFHASEDQTKYAKELYERIRREFPELRIYKFWDRPVGPHPVAMFEVNLFTPAQFGAFVAWLAVWRGPLSALVHPNTIAGPGEDQIEAERRDHSQRAIWMGERLPLDLDLFAKMAERKASAGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZD9</accession>
    <name>G4MZD9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Urea carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_15535</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713501.1">
        <property type="nucleotide sequence ID" value="XM_003713453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZD9"/>
    <dbReference type="SMR" id="G4MZD9"/>
    <dbReference type="FunCoup" id="G4MZD9">
        <property type="interactions" value="170"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZD9"/>
    <dbReference type="GeneID" id="12987104"/>
    <dbReference type="KEGG" id="mgr:MGG_15535"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15535"/>
    <dbReference type="eggNOG" id="KOG0238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002162_2_0_1"/>
    <dbReference type="InParanoid" id="G4MZD9"/>
    <dbReference type="OMA" id="PACKTID"/>
    <dbReference type="OrthoDB" id="167809at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004847">
        <property type="term" value="F:urea carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000010">
        <property type="entry name" value="Propionyl-CoA carboxylase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053844">
        <property type="entry name" value="AH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003778">
        <property type="entry name" value="CT_A_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014084">
        <property type="entry name" value="Urea_COase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00724">
        <property type="entry name" value="urea_amlyse_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02712">
        <property type="entry name" value="urea_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF128">
        <property type="entry name" value="UREA AMIDOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21986">
        <property type="entry name" value="AH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02626">
        <property type="entry name" value="CT_A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00796">
        <property type="entry name" value="AHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00797">
        <property type="entry name" value="AHS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160467">
        <property type="entry name" value="PH0987 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="10">
        <location>
            <begin position="72"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="191"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="1195"/>
            <end position="1273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA53694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1276" mass="138204" checksum="29A30C11881DFD27" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZX8</accession>
    <name>G4MZX8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_06146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712023.1">
        <property type="nucleotide sequence ID" value="XM_003711975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZX8"/>
    <dbReference type="GeneID" id="2684252"/>
    <dbReference type="KEGG" id="mgr:MGG_06146"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06146"/>
    <dbReference type="eggNOG" id="ENOG502T4AS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032743_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZX8"/>
    <dbReference type="OMA" id="GVHLHEG"/>
    <dbReference type="OrthoDB" id="5224238at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="49229" checksum="E15D016AD4E7BFBC" modified="2011-12-14" version="1">MDSLPVELVRLIFQFCDPDAVKALRECSPKLAELGYEYLVPPVFRSFSWRDDVKRLHAISGHDRLRGAIREVLIDFSHPFEISDCHASFLQTEGDDEPDTSLQSAWERYRQIEALRKSATPFDAQVDLLSEAFSRLPNLQDVRVTFNKTTPDAELLSCALGLPINRKLDRKQACSNLNALISAASQAHVSSLEIDRLPMELFKVPQHRQHWFRNSPAVLANLTRLDVIVDPSEVMLPSAKFRAINGFGHFLQFATNLEQLSLGFHNFASPQYKFAIWFQELVGSSFAFKKLTDLKLEGLSCDESDLRRFLERHGSTLKRLRLGGDWASKPGGPVVGGIQLGRGTFRSLFTSLQNRLPHLERVHLSGHFECGMLDPNSHEKYIFNPILRDDGEDGSDEERGRTLYNSADDGLEFERYLLRGGEYPGTPARSPSPQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N077</accession>
    <name>G4N077_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DnaJ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_07716</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712919.1">
        <property type="nucleotide sequence ID" value="XM_003712871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N077"/>
    <dbReference type="STRING" id="242507.G4N077"/>
    <dbReference type="GeneID" id="2683643"/>
    <dbReference type="KEGG" id="mgr:MGG_07716"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07716"/>
    <dbReference type="eggNOG" id="KOG0724">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037236_1_0_1"/>
    <dbReference type="InParanoid" id="G4N077"/>
    <dbReference type="OMA" id="RYIRHAR"/>
    <dbReference type="OrthoDB" id="413400at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052606">
        <property type="entry name" value="DnaJ_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465771" evidence="8">
        <location>
            <begin position="23"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="9">
        <location>
            <begin position="44"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="208"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="428" mass="47243" checksum="AE3287DCDA6674B0" modified="2011-12-14" version="1">MKFSALSLGLLALLSPLTVAWSAEDREIFRVRDELIAGEGKDVNFYDYVGVAPSASVDEIGKAYRKKSRLLHPDKVKQQLTAERTRQAKEDKSKKPKPPTQAEVRAAVKKASDRQARLSIVANILKSPSRDRYDHFLSNGFPTWKGTNYYYNRYRPGLGTAMFGVFLFGGGLAHYLALYMSWKRQRDFVGRYIKFARQTAWGDNLNIPGVETRARTPPPPVAADDDEGAGPAMAMNRKQRRMQERETRREASKGAVSRTARRARGSAAPSGSATPTPQGSGPTGAKKRVVAENGKVLVVDSLGDVYLEEENEEGQVVEYLLDPNEIPQPTIRDTALVRLPIWAYSRTIGRVLGGKNSEDDAAYDEDAETTPLMDDNEDSASEPGKRTPSTDSAEDFELVEKSVDSLGQAKSSGKSSGNKPGKRKNKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4N094</accession>
    <name>G4N094_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_09149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711239.1">
        <property type="nucleotide sequence ID" value="XM_003711191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N094"/>
    <dbReference type="SMR" id="G4N094"/>
    <dbReference type="GeneID" id="2680076"/>
    <dbReference type="KEGG" id="mgr:MGG_09149"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09149"/>
    <dbReference type="eggNOG" id="ENOG502SH7Q">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_003772_0_0_1"/>
    <dbReference type="InParanoid" id="G4N094"/>
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    <dbReference type="OrthoDB" id="2588159at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
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        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053161">
        <property type="entry name" value="Ulvan_degrading_GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36848">
        <property type="entry name" value="DNA-BINDING PROTEIN (PUTATIVE SECRETED PROTEIN)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36848:SF2">
        <property type="entry name" value="SECRETED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17132">
        <property type="entry name" value="Glyco_hydro_106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="974" mass="105234" checksum="A5BFA24ADC6EBE39" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0L3</accession>
    <name>G4N0L3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">O-methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_16915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712951.1">
        <property type="nucleotide sequence ID" value="XM_003712903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0L3"/>
    <dbReference type="SMR" id="G4N0L3"/>
    <dbReference type="GeneID" id="12985872"/>
    <dbReference type="KEGG" id="mgr:MGG_16915"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16915"/>
    <dbReference type="eggNOG" id="KOG0867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_333191_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0L3"/>
    <dbReference type="OMA" id="WHELANT"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF2">
        <property type="entry name" value="O-METHYLTRANSFERASE CICE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="348"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="618"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="723"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="495"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="507"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="580"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA53144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="858" mass="94129" checksum="A8D499AEF113E79D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0S8</accession>
    <name>G4N0S8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Allantoate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_07428</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711318.1">
        <property type="nucleotide sequence ID" value="XM_003711270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0S8"/>
    <dbReference type="STRING" id="242507.G4N0S8"/>
    <dbReference type="GeneID" id="2683348"/>
    <dbReference type="KEGG" id="mgr:MGG_07428"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07428"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_5_1"/>
    <dbReference type="InParanoid" id="G4N0S8"/>
    <dbReference type="OMA" id="YCAGCIG"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF103">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA51511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="323" mass="35427" checksum="82C0CF503212B88F" modified="2011-12-14" version="1">MNGLAQVLGCLLTYGIGVNDSLGLAPWRTLFLVCGALTIAVGVVFYILMPCGPNNAWFLNERDKEVLSARMAQDREGGDKTSFSVVQLREALRDPKVWCVFWFGVLTTMQAPVLTFASLVINSIGYDRYQTMLYTAPSGAVQIALLWTGVFLCWVMPQKRTFVVLIMIVPPLAATILLLELPLDAGWGVIVASWLASCISAVASPLLSLVSSNFKGNTKRAVVNCLFFMGYCAGCIGAPQLWTERPRYFKGVVTSIVTWLLLAVVVLLYRFLCMRDNTIRDGEVSGSAGTGIEADSGPVTLDKLGQHEADLTDKQDRGFRYSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N119</accession>
    <name>G4N119_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713002.1">
        <property type="nucleotide sequence ID" value="XM_003712954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N119"/>
    <dbReference type="GeneID" id="2683712"/>
    <dbReference type="KEGG" id="mgr:MGG_07785"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07785"/>
    <dbReference type="eggNOG" id="ENOG502SJSX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047427_0_0_1"/>
    <dbReference type="InParanoid" id="G4N119"/>
    <dbReference type="OMA" id="YYMLEAY"/>
    <dbReference type="OrthoDB" id="3642468at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="125"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA53195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="462" mass="53392" checksum="A64A337D51FACE9F" modified="2011-12-14" version="1">MTGLTGVWRRYKLVLNVGHPSFSSSRGPSRDQTAAKWMRYVRTRRRRLQTLGYTFAVDRFICSLDSTPSPADKMPKPKRPPTPTEDSPSDDELVDTTARLELHSRRTDRKQKKNQKRLQKLASRPKVIMDLPHELLIDIFSLVRPSDMFALMRVNRPLHDFIRAESATISRRIISLRYPCLQKCFRLPARLADLDETQRAAVRANVGGGQTQPAARKEEQWGRGDQARGAQDDQQQQQQQQQRSRGWGRTWRLSNHPSHLPHVGRPDADSLCDCVTCTIRWIGLNVIVDFAHWQGHLDSGEPIPMFKSWQAPRWNAELVARHAAVVNRAVVDRDPLWYARILELHLATTVRSIRRHTANKGNKRRRYLLTDEDARSETDAFLERSGPPTIDWPYHRDTYYMLEAYLPNRCWSGDEKRYLYVPAEQHEREVQNIVANTVLQQSRAHGELEEASIPQAPERVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1M1</accession>
    <name>G4N1M1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Retinol dehydrogenase 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_07491</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711400.1">
        <property type="nucleotide sequence ID" value="XM_003711352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1M1"/>
    <dbReference type="SMR" id="G4N1M1"/>
    <dbReference type="STRING" id="242507.G4N1M1"/>
    <dbReference type="GeneID" id="2683411"/>
    <dbReference type="KEGG" id="mgr:MGG_07491"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07491"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_0_1"/>
    <dbReference type="InParanoid" id="G4N1M1"/>
    <dbReference type="OMA" id="DPWGWVD"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF283">
        <property type="entry name" value="RETINOL DEHYDROGENASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="321" mass="34893" checksum="5688AAABB1C0A1C0" modified="2011-12-14" version="1">MAYGAKTTGSAIVGDYASQIANKTILTTGVSPTTLGAAFVTTIATASPALLILAGRNLAKAEETAEAIRAVAPQVPIRTLELDLADKQSVRKAAATVLAWDDVAGIDVLVNNAAIITDEYGTIEGIERVFAVNHLGPFLFTNLVLPKVLAVKGRVVNVASEGHRFSNVRFMDLNFEDGKIYNKWRAYGQSKTANMLFSLSLARKLGSRGLVANSPHPGTIITPLSEGMDLALEYELTRPYDQFVGYYPKERGVIKTLDEGISTHIYAAFEPSLKDHNGTFLLDCHVADPNVDFVMSWAASEVEAEKLWKLSEELVGEKFEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1P6</accession>
    <name>G4N1P6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutaminase GtaA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_07512</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711425.1">
        <property type="nucleotide sequence ID" value="XM_003711377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1P6"/>
    <dbReference type="STRING" id="242507.G4N1P6"/>
    <dbReference type="GeneID" id="2683432"/>
    <dbReference type="KEGG" id="mgr:MGG_07512"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07512"/>
    <dbReference type="eggNOG" id="ENOG502QPQS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008020_1_0_1"/>
    <dbReference type="InParanoid" id="G4N1P6"/>
    <dbReference type="OMA" id="WTGYLVR"/>
    <dbReference type="OrthoDB" id="431715at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032514">
        <property type="entry name" value="GtaA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033433">
        <property type="entry name" value="GtaA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF12">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17168">
        <property type="entry name" value="DUF5127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16335">
        <property type="entry name" value="GtaA_6_Hairpin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465832" evidence="1">
        <location>
            <begin position="18"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A N-terminal" evidence="3">
        <location>
            <begin position="115"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A central" evidence="2">
        <location>
            <begin position="355"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A central" evidence="2">
        <location>
            <begin position="527"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminase A central" evidence="2">
        <location>
            <begin position="686"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="828" mass="92859" checksum="916C11C84A534A12" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1S4</accession>
    <name>G4N1S4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712246.1">
        <property type="nucleotide sequence ID" value="XM_003712198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1S4"/>
    <dbReference type="GeneID" id="12984950"/>
    <dbReference type="KEGG" id="mgr:MGG_16798"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16798"/>
    <dbReference type="HOGENOM" id="CLU_2812898_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1S4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="67" mass="7454" checksum="F228BD24DF778FFF" modified="2011-12-14" version="1">MPFFKPTPVSLAACAFSFQSLELCSSGHGRQLDKAFCVKLILGCVPMNLVFILVGPDSNRYNIIRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4N218</accession>
    <name>G4N218_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713135.1">
        <property type="nucleotide sequence ID" value="XM_003713087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N218"/>
    <dbReference type="GeneID" id="12986060"/>
    <dbReference type="KEGG" id="mgr:MGG_16958"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16958"/>
    <dbReference type="HOGENOM" id="CLU_2109517_0_0_1"/>
    <dbReference type="InParanoid" id="G4N218"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="115" mass="12410" checksum="504CE0F802D7313D" modified="2011-12-14" version="1">MANAEPAACIKIIHNGRALNAIGLTDAIKKQLKFYGITDSKVAVVERLWDRQYGNPRENTPSQALSSQHPHVRVFAQADKVETLYTLPQPTGGSGPGDTAACTPACTRGSEHRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N268</accession>
    <name>G4N268_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711491.1">
        <property type="nucleotide sequence ID" value="XM_003711443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N268"/>
    <dbReference type="GeneID" id="12987066"/>
    <dbReference type="KEGG" id="mgr:MGG_16658"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16658"/>
    <dbReference type="HOGENOM" id="CLU_2109516_0_0_1"/>
    <dbReference type="InParanoid" id="G4N268"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="115" mass="12890" checksum="339475873550E42B" modified="2011-12-14" version="1">MASNHNRVRLNNNRHQRKLLLLRSADLRRGADERAPGATRPKHHGQARLEAREQSRLEEVARLVPYEVVVEVVECAEDGDDYAAGERATGCQCAVRKQGVFGDWSGLQSKATKRT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-02-13" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N287</accession>
    <name>OXR2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-linked oxidoreductase OXR2</fullName>
            <ecNumber evidence="8">1.-.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Pyriculol/pyriculariol biosynthesis cluster protein OXR2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">OXR2</name>
        <name type="ORF">MGG_16812</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2017" name="Microbiology" volume="163" first="541" last="553">
            <title>Unravelling the biosynthesis of pyriculol in the rice blast fungus Magnaporthe oryzae.</title>
            <authorList>
                <person name="Jacob S."/>
                <person name="Groetsch T."/>
                <person name="Foster A.J."/>
                <person name="Schueffler A."/>
                <person name="Rieger P.H."/>
                <person name="Sandjo L.P."/>
                <person name="Liermann J.C."/>
                <person name="Opatz T."/>
                <person name="Thines E."/>
            </authorList>
            <dbReference type="PubMed" id="27902426"/>
            <dbReference type="DOI" id="10.1099/mic.0.000396"/>
        </citation>
        <scope>IDENTIFICATION</scope>
        <scope>INDUCTION</scope>
        <scope>FUNCTION</scope>
        <scope>PATHWAY</scope>
    </reference>
    <comment type="function">
        <text evidence="5 8">FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of pyriculol and pyriculariol, two heptaketides that induce lesion formation upon application on rice leaves but are dispensable for pathogenicity (PubMed:27902426). The highly reducing polyketide synthase synthesizes the heptaketide backbone of pyriculol and pyriculariol (PubMed:27902426). Pyriculol and pyriculariol contain several hydroxyl moieties and double bonds, so it can be assumed that several reduction steps occur during biosynthesis. These reactions could be executed by PKS19 itself or partly by the tailoring enzymes OXR1, OXR2, RED1, RED2 or RED3, identified within the cluster (Probable). The FAD-linked oxidoreductase OXR1 is the only tailoring enzyme for which the function has been determined yet, and is involved in the oxidation of dihydropyriculol and dihydropyriculariol into pyriculol and pyriculariol, respectively (PubMed:27902426).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Polyketide biosynthesis.</text>
    </comment>
    <comment type="induction">
        <text evidence="5">Expression is increased in rice-extract medium (REM) and is correlated with the production of pyriculol.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712306.1">
        <property type="nucleotide sequence ID" value="XM_003712258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N287"/>
    <dbReference type="SMR" id="G4N287"/>
    <dbReference type="STRING" id="242507.G4N287"/>
    <dbReference type="GlyCosmos" id="G4N287">
        <property type="glycosylation" value="4 sites, No reported glycans"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_16812T0">
        <property type="protein sequence ID" value="MGG_16812T0"/>
        <property type="gene ID" value="MGG_16812"/>
    </dbReference>
    <dbReference type="GeneID" id="12984968"/>
    <dbReference type="KEGG" id="mgr:MGG_16812"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16812"/>
    <dbReference type="eggNOG" id="ENOG502SJ3M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_0_1_1"/>
    <dbReference type="InParanoid" id="G4N287"/>
    <dbReference type="OMA" id="FRFYVPI"/>
    <dbReference type="OrthoDB" id="9996127at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF8">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0274">FAD</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465654" description="FAD-linked oxidoreductase OXR2" evidence="2">
        <location>
            <begin position="24"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="79"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="3">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q5BEJ5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="27902426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="6">
        <source>
            <dbReference type="PubMed" id="27902426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="7"/>
    <evidence type="ECO:0000305" key="8">
        <source>
            <dbReference type="PubMed" id="27902426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA52499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="520" mass="56591" checksum="EA22B82227CE8B10" modified="2011-12-14" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2A0</accession>
    <name>G4N2A0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">Homoaconitase, mitochondrial</fullName>
            <ecNumber evidence="5 17">4.2.1.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16 17">Homoaconitate hydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MGG_04842</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 17">Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 17">
            <text>(2R,3S)-homoisocitrate = cis-homoaconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15485"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15404"/>
            <dbReference type="ChEBI" id="CHEBI:58174"/>
            <dbReference type="EC" id="4.2.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-alpha-aminoadipate from 2-oxoglutarate: step 3/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 17">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.36" evidence="5 17"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712319.1">
        <property type="nucleotide sequence ID" value="XM_003712271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2A0"/>
    <dbReference type="SMR" id="G4N2A0"/>
    <dbReference type="FunCoup" id="G4N2A0">
        <property type="interactions" value="130"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N2A0"/>
    <dbReference type="GeneID" id="2675616"/>
    <dbReference type="KEGG" id="mgr:MGG_04842"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04842"/>
    <dbReference type="eggNOG" id="KOG0453">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006714_3_1_1"/>
    <dbReference type="InParanoid" id="G4N2A0"/>
    <dbReference type="OMA" id="EQMGEYC"/>
    <dbReference type="OrthoDB" id="10262323at2759"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER01027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004409">
        <property type="term" value="F:homoaconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01582">
        <property type="entry name" value="Homoaconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01674">
        <property type="entry name" value="Homoaconitase_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000013">
        <property type="entry name" value="Homoaconitase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000016">
        <property type="entry name" value="Homoaconitase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004418">
        <property type="entry name" value="Homoaconitase_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039386">
        <property type="entry name" value="Homoaconitase_swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050067">
        <property type="entry name" value="IPM_dehydratase_rel_enz"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00139">
        <property type="entry name" value="h_aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822:SF2">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43822">
        <property type="entry name" value="HOMOACONITASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 17" id="KW-0408">Iron</keyword>
    <keyword evidence="11 17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="13 17" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="18">
        <location>
            <begin position="74"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="19">
        <location>
            <begin position="576"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EHA52512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="776" mass="83497" checksum="1786613206E739E4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2J5</accession>
    <name>G4N2J5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711511.1">
        <property type="nucleotide sequence ID" value="XM_003711463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2J5"/>
    <dbReference type="SMR" id="G4N2J5"/>
    <dbReference type="STRING" id="242507.G4N2J5"/>
    <dbReference type="GeneID" id="2683514"/>
    <dbReference type="KEGG" id="mgr:MGG_07594"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07594"/>
    <dbReference type="eggNOG" id="KOG1269">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_2_7_1"/>
    <dbReference type="InParanoid" id="G4N2J5"/>
    <dbReference type="OMA" id="WVQDQPA"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF1">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="38"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="269" mass="28881" checksum="1D8BD5430553CD39" modified="2011-12-14" version="1">MADTKELAQTYTAVNNTQYDAGLFLLKQLGLEPGMRVLDVGCGPGNITSYLADVVGASGEVVGVDPSEERIDLARAKITSPGESSGTGARLSFFVGTAEDLSRFATGSFDAVYCNSTLHWVRDQPLALREFARVLKPGGRLGVSGQSGDFVAAHEAIAKTVLGREPYSAYDHSVGAPRFLKRAEMESLLDAAGFGSRSFAINPIFKSTKNGDEMISWLESSSSGKTYGGIPVEMRPQARKEMLVEWDKLTTAEGLTMQLDLLVTVAFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N348</accession>
    <name>G4N348_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Palmitoyl-protein thioesterase 1</fullName>
            <ecNumber evidence="2">3.1.2.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Palmitoyl-protein hydrolase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_04920</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palmitoyl-protein thioesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.22" evidence="2"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712411.1">
        <property type="nucleotide sequence ID" value="XM_003712363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N348"/>
    <dbReference type="SMR" id="G4N348"/>
    <dbReference type="STRING" id="242507.G4N348"/>
    <dbReference type="GeneID" id="2675647"/>
    <dbReference type="KEGG" id="mgr:MGG_04920"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04920"/>
    <dbReference type="eggNOG" id="KOG2541">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050129_0_1_1"/>
    <dbReference type="InParanoid" id="G4N348"/>
    <dbReference type="OMA" id="KFVMVMF"/>
    <dbReference type="OrthoDB" id="10263094at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000107">
        <property type="entry name" value="Palmitoyl-protein thioesterase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002472">
        <property type="entry name" value="Palm_thioest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF8">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02089">
        <property type="entry name" value="Palm_thioest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00414">
        <property type="entry name" value="PPTHIESTRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466052" description="Palmitoyl-protein thioesterase 1" evidence="9">
        <location>
            <begin position="22"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="332" mass="37185" checksum="8E76CCF3B2BFCD5E" modified="2011-12-14" version="1">MSLSYYLKHLFLGSLVTSTLARPQQKPLADDDDDTPLPVVIWHGLGDDYSAQGLRQVGEIVEAANPGTFVYFIRMDDNASQDRSATFFGNLTEQVQKVCDDIASHPILSTAPAIDALGFSQGGQFLRAYVERCNSPPVRSLVTFGSQHNGIIDFKACSATDFLCKGAMALLRGNTFSQFVQSRLVPAQYFRDPANNYDKYLESSNFLADINNERALKNQTYKKNLAKLVNFVMFAFDEDTTVIPRETAWFEEVNGTEVIPLRARKLYTEDWIGLRELDRNGGLKLRTCPGEHMQLSDELLNKTFTEFFGPNNKKFGMGGQAGDLDVTREDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3C0</accession>
    <name>G4N3C0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF967 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_13448</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711605.1">
        <property type="nucleotide sequence ID" value="XM_003711557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3C0"/>
    <dbReference type="SMR" id="G4N3C0"/>
    <dbReference type="FunCoup" id="G4N3C0">
        <property type="interactions" value="23"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N3C0"/>
    <dbReference type="GeneID" id="5050371"/>
    <dbReference type="KEGG" id="mgr:MGG_13448"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13448"/>
    <dbReference type="eggNOG" id="ENOG502S03S">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101036_1_0_1"/>
    <dbReference type="InParanoid" id="G4N3C0"/>
    <dbReference type="OMA" id="AWIDRKR"/>
    <dbReference type="OrthoDB" id="2209940at2759"/>
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        <property type="component" value="Chromosome 3"/>
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    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
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        <property type="entry name" value="Haem-degrading domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PduO/GlcC-like"/>
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        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010371">
        <property type="entry name" value="YBR137W-like"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255:SF1">
        <property type="entry name" value="UPF0303 PROTEIN YBR137W"/>
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    </dbReference>
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        <property type="entry name" value="HbpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="GlcG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA51798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="22213" checksum="FBBDE9F7061710FF" modified="2011-12-14" version="1">MQAQVFRRRNQAPGFGLQEDIKAISECLDPKPIPTPSEDPEQVKSTSDTITLESFTSQDAYELGHLLHARLHPIARWQGRPTLVSISLANGQVLFQCAVGSGTSPDNERWVARKRSTVLRWGCSTWLMHCKYAGDEDKFRAKFGMSPDEASGYAIHGGGFPVRVKGVEGVVAVVVVSGLKQHEDHGVIVETFMEHWEPVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3H8</accession>
    <name>G4N3H8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heterochromatin protein one</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_04964</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712460.1">
        <property type="nucleotide sequence ID" value="XM_003712412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3H8"/>
    <dbReference type="SMR" id="G4N3H8"/>
    <dbReference type="STRING" id="242507.G4N3H8"/>
    <dbReference type="GeneID" id="2675290"/>
    <dbReference type="KEGG" id="mgr:MGG_04964"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04964"/>
    <dbReference type="eggNOG" id="KOG1911">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045874_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3H8"/>
    <dbReference type="OMA" id="KCPLKML"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000792">
        <property type="term" value="C:heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017984">
        <property type="entry name" value="Chromo_dom_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00504">
        <property type="entry name" value="CHROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="63"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA52653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="237" mass="26841" checksum="6581D9CB72B85120" modified="2011-12-14" version="1">MPPAISDDDMSDGSNDLDVVPRRDKKAAHSDDEDDEDDFKEATNGAAVEEEEEEGDEGEEEEYVVEKILSHRIDESDGKLRFEVKWEGFEKKSDRTWEPLENLQGSADEILDEYLQEHGTVAELYESFSKATKTKKRGRPSAGATPGSTKKSRKNGDHPLDSEPPESRKAVAWKPPSGSWEDQIDTVDMTRNDKGELIVWLGWKNGEKSQHKAQQAYTRAPQKMLKFYESKINFTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3I0</accession>
    <name>G4N3I0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Lysyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_04966</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>tRNA(Lys) + L-lysine + ATP = L-lysyl-tRNA(Lys) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="10"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712462.1">
        <property type="nucleotide sequence ID" value="XM_003712414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3I0"/>
    <dbReference type="SMR" id="G4N3I0"/>
    <dbReference type="FunCoup" id="G4N3I0">
        <property type="interactions" value="1198"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N3I0"/>
    <dbReference type="GeneID" id="2675380"/>
    <dbReference type="KEGG" id="mgr:MGG_04966"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04966"/>
    <dbReference type="eggNOG" id="KOG1885">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008255_6_0_1"/>
    <dbReference type="InParanoid" id="G4N3I0"/>
    <dbReference type="OMA" id="DFRNEGM"/>
    <dbReference type="OrthoDB" id="21243at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000050">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000238">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034762">
        <property type="entry name" value="Lys-tRNA-ligase_II_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001756">
        <property type="entry name" value="PRK00484.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918:SF9">
        <property type="entry name" value="LYSINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918">
        <property type="entry name" value="LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039101">
        <property type="entry name" value="LysRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="264"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA52655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="615" mass="70217" checksum="01E17C7CB0E1196A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3T4</accession>
    <name>G4N3T4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD dependent epimerase/dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712514.1">
        <property type="nucleotide sequence ID" value="XM_003712466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3T4"/>
    <dbReference type="SMR" id="G4N3T4"/>
    <dbReference type="STRING" id="242507.G4N3T4"/>
    <dbReference type="GeneID" id="2675407"/>
    <dbReference type="KEGG" id="mgr:MGG_05010"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05010"/>
    <dbReference type="eggNOG" id="ENOG502SND3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_744096_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3T4"/>
    <dbReference type="OMA" id="FESMCKT"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="41576" checksum="B676B934D9E5E167" modified="2011-12-14" version="1">MAPQVLVLGMPRTGTQSIGQALQMLGLGESYHMTTVGPNNHHDAWCTAIEAKFGEKDASEVITQEFFDDLFKGYDAVSDFPASIFYKELLAAYPNAHVILTKRAEDAWFESMCKTLHVAYIKAKAEPSKLAKLYHQHLWADNFLRNGREAYRRHNAGVMAAAADRKVLVFDPSMGWGPLCEFLGKDVPAVGYPSKDMWQGYKRMLKEVEEGRLTEDAITIGARRAQGPKINSAYIYTQSKDAEVKGIKSAYIYTQQKEAGAIKSTGEGIKSAYIYTQQKETDLKTSGEGIKSAYIYTQQKEAKDVEGIRSAYIYTQQKETDLKTSGEGIKSAYIYTQQKEAKDVEGIKSAYIYTQQKEAGIEGIKSAYIYTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3U2</accession>
    <name>G4N3U2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712522.1">
        <property type="nucleotide sequence ID" value="XM_003712474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3U2"/>
    <dbReference type="GeneID" id="2675384"/>
    <dbReference type="KEGG" id="mgr:MGG_05016"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05016"/>
    <dbReference type="HOGENOM" id="CLU_2320859_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3U2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="99" mass="10932" checksum="2A92E6AD6615360B" modified="2011-12-14" version="1">MATAEATTGSERSKYAAPVWTHKSSTFKGDGPGQDAAVLQPCRWADERQQTHRIRTTTTTHPTCAFTIMGSWPRNITPRRTKTTIPCRRSVGATWGLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3Z1</accession>
    <name>G4N3Z1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05893</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711720.1">
        <property type="nucleotide sequence ID" value="XM_003711672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3Z1"/>
    <dbReference type="GeneID" id="2684082"/>
    <dbReference type="KEGG" id="mgr:MGG_05893"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05893"/>
    <dbReference type="HOGENOM" id="CLU_2671562_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3Z1"/>
    <dbReference type="OMA" id="PVKVVHH"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="84" mass="8365" checksum="796DB9399F3EC685" modified="2011-12-14" version="1">MCFGSRRRTGGGGYGARPVVVQETRHHHHGGGGMMGGGGMMGGRRHGGGMHGGGMHGGGMHGGMGGRRGGGGMMGSMMGGRRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4L2</accession>
    <name>G4N4L2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16731</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711834.1">
        <property type="nucleotide sequence ID" value="XM_003711786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4L2"/>
    <dbReference type="GeneID" id="12984225"/>
    <dbReference type="KEGG" id="mgr:MGG_16731"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16731"/>
    <dbReference type="HOGENOM" id="CLU_2638533_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4L2"/>
    <dbReference type="OrthoDB" id="10562531at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="77" mass="8189" checksum="924064BD00B7932F" modified="2011-12-14" version="1">MPAGCTTTRWELAAWPIGSQVVGRAKTNPKLQSPTRTLLSAGQEEKRKLLWVTAPQYADPMSGRAGIGAAKALLLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4T0</accession>
    <name>G4N4T0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712702.1">
        <property type="nucleotide sequence ID" value="XM_003712654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4T0"/>
    <dbReference type="SMR" id="G4N4T0"/>
    <dbReference type="GeneID" id="12985155"/>
    <dbReference type="KEGG" id="mgr:MGG_15135"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15135"/>
    <dbReference type="HOGENOM" id="CLU_1224979_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4T0"/>
    <dbReference type="OrthoDB" id="5239261at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="226" mass="25252" checksum="905EF6581DFA17DE" modified="2011-12-14" version="1">MEADYNSFATDARRQQDGLLAVTEVRARLAEDRCHQRRWNQITREIPIVDAMDIGILGWGQPPERRPRPRRLFSPLRDRYGIRKRLYGIRKEPEKEGPSIFSRSRSHPVQAEKPEYPDGPPIDEYFLRSGRTRWNSFPVNDERWLWCAYLGVSIVAVIVFLLLLVKTLCSGSYGSCLLSAAQLGLVVVVYIVGAVFAGNQLSVDVLLLIGGMIVAAAAGHGLGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N574</accession>
    <name>G4N574_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_06077</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711939.1">
        <property type="nucleotide sequence ID" value="XM_003711891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N574"/>
    <dbReference type="SMR" id="G4N574"/>
    <dbReference type="FunCoup" id="G4N574">
        <property type="interactions" value="1160"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N574"/>
    <dbReference type="GeneID" id="2684232"/>
    <dbReference type="KEGG" id="mgr:MGG_06077"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06077"/>
    <dbReference type="eggNOG" id="KOG1466">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016218_0_1_1"/>
    <dbReference type="InParanoid" id="G4N574"/>
    <dbReference type="OMA" id="GDWESCK"/>
    <dbReference type="OrthoDB" id="10249309at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1070">
        <property type="entry name" value="Translation initiation factor eIF-2B, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051501">
        <property type="entry name" value="eIF2B_alpha/beta/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042528">
        <property type="entry name" value="elF-2B_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="339" mass="36949" checksum="C246B91AA63F0443" modified="2011-12-14" version="1">MSNIVVPEMEASSQAVDAQTNTDIVETYERILASDPELTMPVAAIEALINVLGQTTSSTVMETLDIIRTAADRLRTSVPNPVPLAAGTDLFQQYLLRSLKKQDTNDAHAGFEETRQYLIRNSRVFASRAKQARAEIAERGARIIGEGSCVLTGGGSRTIAAVLLRAAEVHSAEFGSPRFKVVYVVDLRFPSNVVENLRSRGVPVAEVSERDIAHVLRTTGVDFALLGAEVLCQSGGVLSRIGTYNIVELVAAYKKPVYFAAESHKIARVYPLSQLDLPRCGVQQQVANFTTSNEPPKQTSAANEDPIDYTPPKMITKVITEYGTKTPSGIYEMLLDIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5U8</accession>
    <name>G4N5U8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Delta(14)-sterol reductase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">C-14 sterol reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Sterol C14-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_13986</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716043.1">
        <property type="nucleotide sequence ID" value="XM_003715995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5U8"/>
    <dbReference type="SMR" id="G4N5U8"/>
    <dbReference type="FunCoup" id="G4N5U8">
        <property type="interactions" value="495"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5U8"/>
    <dbReference type="GeneID" id="2678847"/>
    <dbReference type="KEGG" id="mgr:MGG_13986"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13986"/>
    <dbReference type="eggNOG" id="KOG1435">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015631_0_3_1"/>
    <dbReference type="InParanoid" id="G4N5U8"/>
    <dbReference type="OMA" id="HSSWHRY"/>
    <dbReference type="OrthoDB" id="10262235at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050613">
        <property type="term" value="F:Delta14-sterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018083">
        <property type="entry name" value="Sterol_reductase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF52">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE TM7SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01017">
        <property type="entry name" value="STEROL_REDUCT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01018">
        <property type="entry name" value="STEROL_REDUCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12 13" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU369120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA49724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="480" mass="54070" checksum="B76389FB38F3CE9E" modified="2011-12-14" version="1">MALAVRTKYEFFGPPGATAIVFGLPVLLWTLFFGCNDVSGCPAPALLSPRDLTWAKLKSEIPWPENGVRGFVSWEVTFWTFAYYFLSLVLHRVMPAQEVVGTKLRDSGRPLTYRFNAFNASVVQLIACAFGTYLQGADFVVWKFMTDNYLQLLTTNILLAYAISIWVYAKSFSVKPGNPELRELAQGGHTGNVIYDFYIGRELNPRVTWPFFGEIDVKTFLEMRPGLTGWILLNCANIAKQYRNYGFVSDSILFTTAVQAYYVLEGQYMETGILTMMDITTDGLGFMLTFGDIAWLPFLYSTQTRYLSTYPVTLGPAGLAIVSAVFATGLYIFRSSNSQKNLFRRDPNHPSVKNLSYIQTKRGTRLLTAGWWGMSRHINYFGDWLQASPFSLPTGIAGYMILPAGSAVAEAGATMVDGRQVIQGAARGWGMLFTYLYVVYFAVLLIHREGRDDVACSEKYGEDWEKYKKAVKYKILPYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5Z1</accession>
    <name>G4N5Z1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-ketoglutarate-dependent taurine dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03117</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716886.1">
        <property type="nucleotide sequence ID" value="XM_003716838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5Z1"/>
    <dbReference type="SMR" id="G4N5Z1"/>
    <dbReference type="FunCoup" id="G4N5Z1">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="GeneID" id="2676900"/>
    <dbReference type="KEGG" id="mgr:MGG_03117"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03117"/>
    <dbReference type="eggNOG" id="ENOG502QS4K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036005_1_0_1"/>
    <dbReference type="InParanoid" id="G4N5Z1"/>
    <dbReference type="OMA" id="WNKNDMA"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000005">
        <property type="entry name" value="TfdA family taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF20">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="45"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA50567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="371" mass="41201" checksum="19AFC7550715ED26" modified="2011-12-14" version="1">MPSINIPATDLVADSNIFGGNAAARTRRTQPIVYSGSLDQYKQADVTPVIGTEFEGLQVRDLLKAEDHVIRDLAVTISRRGVVFLREQDVTPTEMKDFMLRLTDLAGCPESSGLHVHPLTEEGSELGDQISVISSEKQKKGGGLTHMLSDVSRLASAAWHTDISFEPVPSDYAMLKIHTLPPTGGDTLWASGYEIYDRLSPAMQKMLEGLTATHDATFFLDEAERLGNPLREGIRGSPLNQGKGLKAVHPVIRTNPVTGWKSVYVNRGFTKRINGVTRDESDLLLPYLFNLVTQNHDAQVRFKWRKNDLAIWDNRSTWHCATYDYDDARAGDRVASLGEAPYLDLTSSGRREALLREETEGKRGEKRKAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6Y0</accession>
    <name>G4N6Y0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ataxin-10 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a role in the regulation of cytokinesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ataxin-10 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA50744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003717015.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_06497"/>
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        <property type="component" value="Chromosome 4"/>
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        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="Ataxin-10/CTR86_families"/>
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        <property type="entry name" value="Ataxin-10_domain"/>
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    </dbReference>
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        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Atx10homo_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
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        <location>
            <begin position="780"/>
            <end position="842"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="383"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="697"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="845"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="903"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="411"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
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            <begin position="431"/>
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    </feature>
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        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
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            <begin position="733"/>
            <end position="743"/>
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    </feature>
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        <location>
            <begin position="848"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="942"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008384"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044746"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00044801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF09759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA50744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="964" mass="107830" checksum="95634887D0B4C389" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7L1</accession>
    <name>G4N7L1_PYRO7</name>
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        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_06386</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35925" checksum="7DBF13C18C0D1BFB" modified="2011-12-14" version="1">MNGIAPALSEAEKEHFLEKGWVKIPKAFTREQAGDATKDVWTRLGMSPTDKSTWSSLRTNMPAAQLHFDASEFAPRAWAAVNELCGGEDRIDSRCRTWRDTFIVNLGTPENEGKEVVPKELDNYHVDGDFFIHYLDSPEQGLLIIPLFTDVVPGGGGTYICPDAMPKVARWLYDHPEGVSPRMVPRGEPDFEKEANLDWFLDLAQTCEDFVEVTGEAGDVYLLHPLMLHSASTNPLRRVRIITNPPVSLKEPFCFDRPDGNYSLVELRTIRALGKKAPLDWKIKGPRENVIPARVRRWEKMKADEAKRLEEARKLVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N815</accession>
    <name>G4N815_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Condensin complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_03487</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CND1 (condensin subunit 1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003716388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N815"/>
    <dbReference type="SMR" id="G4N815"/>
    <dbReference type="FunCoup" id="G4N815">
        <property type="interactions" value="564"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N815"/>
    <dbReference type="GeneID" id="2676444"/>
    <dbReference type="KEGG" id="mgr:MGG_03487"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03487"/>
    <dbReference type="eggNOG" id="KOG0414">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001867_1_0_1"/>
    <dbReference type="InParanoid" id="G4N815"/>
    <dbReference type="OMA" id="DVIAKLW"/>
    <dbReference type="OrthoDB" id="436262at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000791">
        <property type="term" value="C:euchromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140602">
        <property type="term" value="C:nucleolar peripheral inclusion body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="entry name" value="Condensin complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Condensin complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007673">
        <property type="entry name" value="Condensin_cplx_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024324">
        <property type="entry name" value="Condensin_cplx_su1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF2">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12922">
        <property type="entry name" value="Cnd1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017127">
        <property type="entry name" value="Condensin_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="6 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin complex subunit 1 N-terminal" evidence="13">
        <location>
            <begin position="86"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="1034"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="821"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="904"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="904"/>
            <end position="919"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009606"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017127"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12922"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA50117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1218" mass="135215" checksum="21EB79D1FD06A9C0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8E0</accession>
    <name>G4N8E0_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17200</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003717259.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_17200"/>
    <dbReference type="HOGENOM" id="CLU_1289154_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8E0"/>
    <dbReference type="Proteomes" id="UP000009058">
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="214" mass="23973" checksum="084389F5FDC2A87B" modified="2011-12-14" version="1">MARQRATHSVNGHQEIERQRPEKQQGTNNSASLSAKALICGLVEERTTGPSGLGFTTRKKKSAGRNSDKCTVNTFPTMAGRSAPSNPGFGDVALFDQPENDQTPPPMDLGTRSFPDWWSVQRKGPRRIGDPLQKWGVGVLFLNLSPRDTTNTRNRSSYRSFTRGYASFFLIKKSDLQGHVWWDRWGARRRANDNFSVLFFTDSNQARHSSLLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8G3</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17203</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717330.1">
        <property type="nucleotide sequence ID" value="XM_003717282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8G3"/>
    <dbReference type="GeneID" id="12985644"/>
    <dbReference type="KEGG" id="mgr:MGG_17203"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17203"/>
    <dbReference type="HOGENOM" id="CLU_2427452_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8G3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="91" mass="9698" checksum="62D16A8905BAFE5C" modified="2011-12-14" version="1">MADEKARSAEKMTRQEEEEATDYNPTLLVVRGSCLSGVWQGMYYLLDVPYKMGKAGGRGNAVAQGLNPTSGLLGSGALRNETTTLKAGDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9B0</accession>
    <name>G4N9B0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Acyl-coenzyme A thioesterase THEM4</fullName>
            <ecNumber evidence="19">3.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="21">Thioesterase superfamily member 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="28" type="ORF">MGG_10034</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="28 29" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="29">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:40151"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:32395"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57368"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:40152"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(9Z)-octadecenoyl-CoA + H2O = (9Z)-octadecenoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:40139"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30823"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:40140"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>decanoyl-CoA + H2O = decanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:40059"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:27689"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:61430"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:40060"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>dodecanoyl-CoA + H2O = dodecanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:30135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18262"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57375"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:30136"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16645"/>
            <dbReference type="ChEBI" id="CHEBI:7896"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="EC" id="3.1.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:16646"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>octanoyl-CoA + H2O = octanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:30143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:25646"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57386"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:30144"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>tetradecanoyl-CoA + H2O = tetradecanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:40119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30807"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="26">
            <dbReference type="Rhea" id="RHEA:40120"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Ruffle membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Mitochondrion inner membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the THEM4/THEM5 thioesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.2" evidence="19"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717470.1">
        <property type="nucleotide sequence ID" value="XM_003717422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9B0"/>
    <dbReference type="SMR" id="G4N9B0"/>
    <dbReference type="STRING" id="242507.G4N9B0"/>
    <dbReference type="GeneID" id="2680991"/>
    <dbReference type="KEGG" id="mgr:MGG_10034"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10034"/>
    <dbReference type="HOGENOM" id="CLU_052827_4_1_1"/>
    <dbReference type="InParanoid" id="G4N9B0"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052365">
        <property type="entry name" value="THEM4/THEM5_acyl-CoA_thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12418">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE THEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12418:SF19">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE THEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thioesterase" evidence="27">
        <location>
            <begin position="48"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00035852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00037002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00038456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00038848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00040123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00043210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00047588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00047734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00047969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00048074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00048180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="EHA51151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="123" mass="13560" checksum="3FDFAA266576A932" modified="2011-12-14" version="1">MNLPHCLPGFLCLDRIPTKPDGVVEERITLYAIGQGLEGWIGMTHGGMCNVRQGGPWGAQKVVTKYLNITYVRPVPAPAVVQCRAKVEKVEGRKIFYKTYLQDGDGDNLAVGDSLYVVLNQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9U4</accession>
    <name>G4N9U4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">molybdopterin adenylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03258</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenylyl-molybdopterin + molybdate = Mo-molybdopterin + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>molybdopterin + ATP + H(+) = adenylyl-molybdopterin + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:31331"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58698"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MoeA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.75" evidence="2"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716715.1">
        <property type="nucleotide sequence ID" value="XM_003716667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9U4"/>
    <dbReference type="SMR" id="G4N9U4"/>
    <dbReference type="STRING" id="242507.G4N9U4"/>
    <dbReference type="GeneID" id="2676589"/>
    <dbReference type="KEGG" id="mgr:MGG_03258"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03258"/>
    <dbReference type="eggNOG" id="KOG2371">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010186_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9U4"/>
    <dbReference type="OMA" id="FINANCW"/>
    <dbReference type="OrthoDB" id="6777263at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061598">
        <property type="term" value="F:molybdopterin adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.10">
        <property type="entry name" value="Molybdopterin biosynthesis moea protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.190.11">
        <property type="entry name" value="Molybdopterin biosynthesis moea protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192:SF30">
        <property type="entry name" value="MOLYBDOPTERIN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="MOLYBDOPTERIN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="MoeA N-terminal region -like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="3" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoeA N-terminal and linker" evidence="5">
        <location>
            <begin position="5"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="MoaB/Mog" evidence="4">
        <location>
            <begin position="218"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="368" mass="39553" checksum="CA0FCC989BAFE573" modified="2011-12-14" version="1">MATSYTTALELLQQASQEAKPANDGGQVEVVPLLESTGRIAARNIRSRLTTPEFDTSAMDGYAISSAATRDATPESPLIFHVKGAIAAGDEPKSWTTRSVDDGGIAGACIEIMTGARFPEPGPGEEELDACIKMEDTMYISSPSPYDRQGHVSLKPAKFIVVVRPVPRCANRRFAGEDICEGDTVIRAGQMICASHLMPLASVGVQSVAVQPMPIVRVFSTGKELLREQNEVANGANQPHGRDKLHTADPRESSIRDVNGVFLTAAFREVGAESQFLGQLADETKDIADAVSHILSSNPTPNVIVTSGGVSVGKFDHAEKRRSSAFLETREQRQPALDFSRAQAHNAEKTRIMIASSLDVWVLEKEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA76</accession>
    <name>G4NA76_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_08446</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715945.1">
        <property type="nucleotide sequence ID" value="XM_003715897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA76"/>
    <dbReference type="SMR" id="G4NA76"/>
    <dbReference type="GeneID" id="2678760"/>
    <dbReference type="KEGG" id="mgr:MGG_08446"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08446"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="InParanoid" id="G4NA76"/>
    <dbReference type="OMA" id="ANQCWSL"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000117">
        <property type="entry name" value="MFS hexose transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF29">
        <property type="entry name" value="SUGAR TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="39"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA49626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="531" mass="59884" checksum="D15A78FF70F8F837" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAD4</accession>
    <name>G4NAD4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA polymerase II transcription factor B subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_03192</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <source>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB77</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718423.1">
        <property type="nucleotide sequence ID" value="XM_003718375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB77"/>
    <dbReference type="GeneID" id="5050816"/>
    <dbReference type="KEGG" id="mgr:MGG_14669"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14669"/>
    <dbReference type="HOGENOM" id="CLU_1686985_0_0_1"/>
    <dbReference type="InParanoid" id="G4NB77"/>
    <dbReference type="OrthoDB" id="10566130at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="156" mass="16563" checksum="5E7ED99CC442B7BE" modified="2011-12-14" version="1">MCECVVLHGPSWLGSLTARALRSQYCYTVPRQGAVLEPPGPSTGKLSKVGRTLDSHSIFTVAKQNQNDAGNDDISTLVALLSEAPASPVLSLYLKLSSGMTPTSRLSWNPPSPPIFTIFTTRQWRLTGVLSSKMPSGTGIGIVPTSPMSESESSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBH2</accession>
    <name>G4NBH2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-phytase</fullName>
            <ecNumber evidence="2">3.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_00538</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.8" evidence="2"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718513.1">
        <property type="nucleotide sequence ID" value="XM_003718465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBH2"/>
    <dbReference type="SMR" id="G4NBH2"/>
    <dbReference type="GeneID" id="2674531"/>
    <dbReference type="KEGG" id="mgr:MGG_00538"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00538"/>
    <dbReference type="eggNOG" id="KOG1382">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020880_2_1_1"/>
    <dbReference type="InParanoid" id="G4NBH2"/>
    <dbReference type="OMA" id="YNAQALC"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:inositol hexakisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000147">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF43">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01240)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA48929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="597" mass="65775" checksum="55898079DD36FD6C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBT4</accession>
    <name>G4NBT4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00486</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718576.1">
        <property type="nucleotide sequence ID" value="XM_003718528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBT4"/>
    <dbReference type="SMR" id="G4NBT4"/>
    <dbReference type="GeneID" id="2674835"/>
    <dbReference type="KEGG" id="mgr:MGG_00486"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00486"/>
    <dbReference type="eggNOG" id="KOG4157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116866_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBT4"/>
    <dbReference type="OMA" id="RECWCAQ"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466420" description="WSC domain-containing protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="32"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA48992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="161" mass="16790" checksum="D59248A7B2F669A6" modified="2011-12-14" version="1">MLPQLLPLLLITLCQAGAAQDLSIFSPPSSSKYKYHGCYNETTGLPGTSGVQRAIDGKHKTAPGSMTVQSCLDFCGSDDTVYKFAGIEFSRECWCGNILSGLSVRVDDDQCNTACDGNASIACGGPLKLSVYMSGAHRVAVTSANLIIGITAMAAGIISMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC23</accession>
    <name>G4NC23_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial 2-oxodicarboxylate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_11577</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718610.1">
        <property type="nucleotide sequence ID" value="XM_003718562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC23"/>
    <dbReference type="SMR" id="G4NC23"/>
    <dbReference type="FunCoup" id="G4NC23">
        <property type="interactions" value="226"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NC23"/>
    <dbReference type="GeneID" id="5050731"/>
    <dbReference type="KEGG" id="mgr:MGG_11577"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11577"/>
    <dbReference type="eggNOG" id="KOG0754">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015166_5_2_1"/>
    <dbReference type="InParanoid" id="G4NC23"/>
    <dbReference type="OMA" id="LPFQYQF"/>
    <dbReference type="OrthoDB" id="434783at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005310">
        <property type="term" value="F:dicarboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006839">
        <property type="term" value="P:mitochondrial transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000034">
        <property type="entry name" value="Mitochondrial 2-oxodicarboxylate carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051752">
        <property type="entry name" value="Mito_2-oxodicarb_carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46356">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46356:SF1">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="7"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="107"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="202"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA49026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="305" mass="33407" checksum="85D68B97BDA5D0E9" modified="2011-12-14" version="1">MSSEKPLPFIYQFAAGAVAGVSEILVMYPLDVVKTRMQLQTSTAVGSDAYNGTLDCFRKIIKNEGFSRLYRGITAPILMEAPKRATKFAANDEWGKFYRNAFGQEKMTQGLSVLTGASAGATESFVVVPFELIKIRLQDKVSASKYNGPVDVLLKTVKNEGLLALYTGLESTMWRHILWNAGYFGCIHQVRQLLPKAETKKGQMASDIVAGSVGGTVGTILNTPMDVVKSRIQNTTKVAGVTPKYNWAWPALGTVMREEGFAALYKGFLPKVLRLGPGGGILLVVYGGVMDFFRKMRDEADLKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC73</accession>
    <name>G4NC73_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Oligonucleotide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_11429</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717806.1">
        <property type="nucleotide sequence ID" value="XM_003717758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC73"/>
    <dbReference type="SMR" id="G4NC73"/>
    <dbReference type="FunCoup" id="G4NC73">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NC73"/>
    <dbReference type="GeneID" id="5050592"/>
    <dbReference type="KEGG" id="mgr:MGG_11429"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11429"/>
    <dbReference type="eggNOG" id="ENOG502QQ2H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010539_2_0_1"/>
    <dbReference type="InParanoid" id="G4NC73"/>
    <dbReference type="OMA" id="TPTAYVW"/>
    <dbReference type="OrthoDB" id="627262at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF0">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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</entry>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
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                <person name="Bohnert H."/>
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                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Abouelleil A."/>
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                <person name="Brown A."/>
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                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
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                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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    </reference>
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        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
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    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="412"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="574" mass="62581" checksum="94CF85D02F5570AF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDC9</accession>
    <name>G4NDC9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endoplasmic reticulum-Golgi intermediate compartment protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00949</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Plays a role in transport between endoplasmic reticulum and Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Golgi apparatus membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ERGIC family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718002.1">
        <property type="nucleotide sequence ID" value="XM_003717954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDC9"/>
    <dbReference type="SMR" id="G4NDC9"/>
    <dbReference type="FunCoup" id="G4NDC9">
        <property type="interactions" value="368"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NDC9"/>
    <dbReference type="GeneID" id="2674635"/>
    <dbReference type="KEGG" id="mgr:MGG_00949"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00949"/>
    <dbReference type="eggNOG" id="KOG2667">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034705_2_0_1"/>
    <dbReference type="InParanoid" id="G4NDC9"/>
    <dbReference type="OMA" id="MTNHYLR"/>
    <dbReference type="OrthoDB" id="5541786at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033116">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF81">
        <property type="entry name" value="ER-DERIVED VESICLES PROTEIN ERV41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="7">
        <location>
            <begin position="23"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="6">
        <location>
            <begin position="183"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU369013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="376" mass="42078" checksum="BB4B7C9727D0AF36" modified="2011-12-14" version="1">MMNGYEKNNHDEDPFAPSGSVVSAFDAFPKSKPQYVTRTSGGGKWTVAMLLVSAILTWSELARWWRGVETHTFAVEKGVGQSMQINMDTVVHMRCQDIHVNVQDAAGDRIMAAARLKMDDTTWAQWVDGSGVHRLGHDQHGKVVTGEGHEEGFGEEHIHDIVALGKKRARWSKTPRLWGATPDSCRIFGSLDLNKVQGDFHITARGHGYIEFGDHLDHSAFNFSHIVNEFSFGDFYPSLVNPLDKTVNTCEKNFHKFQYFLSVVPTLYSVKSSTGAFGYSTIFTNQYAVTEQSSEISEMNVPGIFFKYDIEPILLDIEESRDTILVFLIKVINILSGAMVAGHWGFTMSEWIKEVLGKRRRASSNGVLGNKAGYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDF9</accession>
    <name>G4NDF9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Metalloreductase Fre8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_14647</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferric reductase (FRE) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718032.1">
        <property type="nucleotide sequence ID" value="XM_003717984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDF9"/>
    <dbReference type="STRING" id="242507.G4NDF9"/>
    <dbReference type="GeneID" id="5050638"/>
    <dbReference type="KEGG" id="mgr:MGG_14647"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14647"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019268_1_0_1"/>
    <dbReference type="InParanoid" id="G4NDF9"/>
    <dbReference type="OMA" id="NPFTIAH"/>
    <dbReference type="OrthoDB" id="10006946at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
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        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
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        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051410">
        <property type="entry name" value="Ferric/Cupric_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361:SF9">
        <property type="entry name" value="FERRIC REDUCTASE TRANSMEMBRANE COMPONENT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32361">
        <property type="entry name" value="FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="264"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="519"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA48448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="620" mass="68513" checksum="24569949DA59CBBE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDM3</accession>
    <name>G4NDM3_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17503</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718892.1">
        <property type="nucleotide sequence ID" value="XM_003718844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDM3"/>
    <dbReference type="GeneID" id="12985049"/>
    <dbReference type="KEGG" id="mgr:MGG_17503"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17503"/>
    <dbReference type="HOGENOM" id="CLU_578799_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDM3"/>
    <dbReference type="OMA" id="EELVVCC"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="205"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="472" mass="49979" checksum="7B21AB210F18ECBC" modified="2011-12-14" version="1">MALAEALFFSGPLVPLPLLSLLLPPPLLLLGVLSLLLLGAVGVAEGLIVKDVVEELVVCCQPGQLDWLEGQMVVLLTEVVYIVDVLLVIVGGEDDVVVPVAVVDPGWALAVAGTTVVEMAAVVVTTVGFLSSQAQSLFVVGQAIMVVALVVYIVEVLEDPEADEVELEVEEVVVDLVNIALENADTAEGNRVFVLICVVKTVDVVEVLAEEVVVEEEEEEELVEDEDVVEEDVDCDELVLLLDEVDELEEVDEAVEDELGVVVAVGVVIQRVDEIGSFVVCEADVVVEVVTEVLVDVVSDDVVEVDDEEVELDVELDDELEVVVADTDAGVVVELVVMDTGGMSGELVEVLEVELEDVVLVLVVVELEVDVDTELVEEAELVEEAELVVGAVLVDAVLVSDDVPVKDDVLVEEVVDAGGEPGSGVEVVSGDVEVVPADVDDTAVLVEVDAGLVVVALELAVELVEVELMLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE90</accession>
    <name>G4NE90_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17527</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719003.1">
        <property type="nucleotide sequence ID" value="XM_003718955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE90"/>
    <dbReference type="GeneID" id="12985092"/>
    <dbReference type="KEGG" id="mgr:MGG_17527"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17527"/>
    <dbReference type="HOGENOM" id="CLU_2688299_0_0_1"/>
    <dbReference type="InParanoid" id="G4NE90"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="74" mass="8486" checksum="DE44BFA71CD17AD4" modified="2011-12-14" version="1">MDSRFEPTDECYYREATGWAKSNTNLVGRRNSARGAPGSYGRRSLYKEGETESGKIEQPASLLYEYLYMHKRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEF5</accession>
    <name>G4NEF5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17529</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719016.1">
        <property type="nucleotide sequence ID" value="XM_003718968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEF5"/>
    <dbReference type="GeneID" id="12985122"/>
    <dbReference type="KEGG" id="mgr:MGG_17529"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17529"/>
    <dbReference type="HOGENOM" id="CLU_2386605_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEF5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="94" mass="10186" checksum="807A48EC4F707567" modified="2011-12-14" version="1">MKLRNRLGLGLLSFMEAVKVPEKACERVYGKEKVADGTGHPITTHKPRCILIQAQHAGFRTTGGRILNNDQLSGSEGHCVVATAPILVVSEIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEN5</accession>
    <name>G4NEN5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718249.1">
        <property type="nucleotide sequence ID" value="XM_003718201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEN5"/>
    <dbReference type="GeneID" id="2674323"/>
    <dbReference type="KEGG" id="mgr:MGG_00751"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00751"/>
    <dbReference type="eggNOG" id="ENOG502RQX6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_497021_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEN5"/>
    <dbReference type="OrthoDB" id="5245117at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="548" mass="61437" checksum="A08AB4AEFBEA6C73" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEV3</accession>
    <name>G4NEV3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00035</name>
        <name evidence="3" type="ORF">MGG_14724</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719110.1">
        <property type="nucleotide sequence ID" value="XM_003719062.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719133.1">
        <property type="nucleotide sequence ID" value="XM_003719085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEV3"/>
    <dbReference type="STRING" id="242507.G4NEV3"/>
    <dbReference type="GeneID" id="2674987"/>
    <dbReference type="GeneID" id="5049402"/>
    <dbReference type="KEGG" id="mgr:MGG_00035"/>
    <dbReference type="KEGG" id="mgr:MGG_14724"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00035"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14724"/>
    <dbReference type="eggNOG" id="ENOG502S8TM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_573736_0_0_1"/>
    <dbReference type="OMA" id="ESTNCEC"/>
    <dbReference type="OrthoDB" id="10029326at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF16">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="476" mass="53339" checksum="1F1E5A5DA3CDB7E1" modified="2011-12-14" version="1">MDQIYANGIINIAAGASEDSSEGLFRQRSGSSALQCPLVVGTEGMWPPEQHEGIADFIKRAKRDEGTLFERCYFVSKDDWQRSVHQSTLARRGWVLQERLLSPRILTFGTRQIYWQCGETSCNEEGSPTDDDYTLKMQFATMLSGNSDWDWEHSLSASSLDIWRSVVTDYSQTRLTKHTDRLVALSGLAKTFCRAMPHNQYLAGLWKDSLPNDLLWEVCYVEGPATSPPPCAGPASRGYCAPTFCWASAAFPCTLNLQFCFAGWLSFGLLFTVLDITLDYATKEVTGPVTGGCLDIMAKIRPFRLVSPSNFDAGRIPKKKLCPGFLNAFSPPEPGRSELGEFSWPLVRLDRPLQVPSSSDEILFFFVVGIPVKLEGFGPNELAECIEFFPEFEVGEWKILLAKCMLLEAVDADAGVYRRVGMATSYELFRKDAENEKDGFQDLVHFLLKNEPYQGEPDTPIPCRGMDGEEHVFRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF71</accession>
    <name>G4NF71_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Beta-glucosidase cel3A</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Beta-D-glucoside glucohydrolase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Cellobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Gentiobiase cel3A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_14903</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719616.1">
        <property type="nucleotide sequence ID" value="XM_003719568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF71"/>
    <dbReference type="SMR" id="G4NF71"/>
    <dbReference type="STRING" id="242507.G4NF71"/>
    <dbReference type="GeneID" id="12986087"/>
    <dbReference type="KEGG" id="mgr:MGG_14903"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14903"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004542_2_1_1"/>
    <dbReference type="InParanoid" id="G4NF71"/>
    <dbReference type="OMA" id="MHEVYLC"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF5">
        <property type="entry name" value="BETA-GLUCOSIDASE M-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Fibronectin type III-like" evidence="18">
        <location>
            <begin position="676"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00070030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00078013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00083231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00083611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA47249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="758" mass="82190" checksum="0D55370CF5B33032" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFD3</accession>
    <name>G4NFD3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719528.1">
        <property type="nucleotide sequence ID" value="XM_003719480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFD3"/>
    <dbReference type="SMR" id="G4NFD3"/>
    <dbReference type="GeneID" id="12985989"/>
    <dbReference type="KEGG" id="mgr:MGG_17647"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17647"/>
    <dbReference type="HOGENOM" id="CLU_2740535_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFD3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="71" mass="7736" checksum="7CC0DF218C45DF8F" modified="2011-12-14" version="1">MRKRHESGGRPRGDTRNRLKTLTAYVDQALKGGNVRIRPPDLPSESRLGSTSHAEPGVGQGSTYSGFKRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFE9</accession>
    <name>G4NFE9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719544.1">
        <property type="nucleotide sequence ID" value="XM_003719496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFE9"/>
    <dbReference type="SMR" id="G4NFE9"/>
    <dbReference type="STRING" id="242507.G4NFE9"/>
    <dbReference type="GeneID" id="12986000"/>
    <dbReference type="KEGG" id="mgr:MGG_17657"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17657"/>
    <dbReference type="HOGENOM" id="CLU_1865503_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFE9"/>
    <dbReference type="OrthoDB" id="9997739at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15917" checksum="09388040DDB180DE" modified="2011-12-14" version="1">MLWDDFERSWRMDLSVFTKKDTFDTGSGLGVNTLIHHGRVYVLADRYGIGRLMDVSLQKLHQALVKSKVPETNLNDIVAMVRFCYAELVPERLRRLVVHYISCNLETLWKIKEFQELVEDYGNLARALVGSMLLRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFY7</accession>
    <name>G4NFY7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719311.1">
        <property type="nucleotide sequence ID" value="XM_003719263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFY7"/>
    <dbReference type="GeneID" id="5051848"/>
    <dbReference type="KEGG" id="mgr:MGG_14375"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14375"/>
    <dbReference type="HOGENOM" id="CLU_1315607_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFY7"/>
    <dbReference type="OMA" id="TKWRPVV"/>
    <dbReference type="OrthoDB" id="4779809at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="209" mass="21722" checksum="0317BDC618B377A6" modified="2011-12-14" version="1">MPHHVSKMSDLMFPGLADRAAKNSQLRGAGASKSSPAAGPRSTGRVRTPLPDKGKPRSASGPASRVGKTKGKKRASVAAAPRPRPAAGVVRPRSCLGCLRSALAGKQGSGDLAVCRETSPPSGRCYKCASGHSCEEIPAPARPPAVRFLAAVAKGDKAAITKWRPVVKGVLEIWEEEKEGGGVAVAAMSAEEKKEEAKRAALQLVEVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJZ5</accession>
    <name>G4NJZ5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyridoxal-5'-phosphate-dependent protein beta subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_14215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720506.1">
        <property type="nucleotide sequence ID" value="XM_003720458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJZ5"/>
    <dbReference type="SMR" id="G4NJZ5"/>
    <dbReference type="STRING" id="242507.G4NJZ5"/>
    <dbReference type="GeneID" id="5048710"/>
    <dbReference type="KEGG" id="mgr:MGG_14215"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14215"/>
    <dbReference type="eggNOG" id="KOG1250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020984_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJZ5"/>
    <dbReference type="OMA" id="VWAKLEC"/>
    <dbReference type="OrthoDB" id="4418812at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF19">
        <property type="entry name" value="ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="5">
        <location>
            <begin position="28"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="368"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="371"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA45763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="879" mass="95951" checksum="1E6925D56DB6D305" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKI8</accession>
    <name>G4NKI8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidylinositol 3-kinase VPS34</fullName>
            <ecNumber evidence="7">2.7.1.137</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_03069</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12709"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.137"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:12710"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.137" evidence="7"/>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720606.1">
        <property type="nucleotide sequence ID" value="XM_003720558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKI8"/>
    <dbReference type="SMR" id="G4NKI8"/>
    <dbReference type="FunCoup" id="G4NKI8">
        <property type="interactions" value="814"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NKI8"/>
    <dbReference type="GeneID" id="2682622"/>
    <dbReference type="KEGG" id="mgr:MGG_03069"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03069"/>
    <dbReference type="eggNOG" id="KOG0906">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004869_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKI8"/>
    <dbReference type="OMA" id="LHKFAQY"/>
    <dbReference type="OrthoDB" id="67688at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016303">
        <property type="term" value="F:1-phosphatidylinositol-3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032120">
        <property type="term" value="P:ascospore-type prospore membrane formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051365">
        <property type="term" value="P:cellular response to potassium ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000425">
        <property type="term" value="P:pexophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd08397">
        <property type="entry name" value="C2_PI3K_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00870">
        <property type="entry name" value="PI3Ka_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00896">
        <property type="entry name" value="PI3Kc_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 3-kinase catalytic subunit type 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 3-kinase catalytic subunit type 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.70:FF:000009">
        <property type="entry name" value="Phosphatidylinositol 3-kinase VPS34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057756">
        <property type="entry name" value="PI3-kinase_type3/VPS34_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002420">
        <property type="entry name" value="PI3K-type_C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008290">
        <property type="entry name" value="PI3K_Vps34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF7">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00792">
        <property type="entry name" value="PI3K_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000587">
        <property type="entry name" value="PI3K_Vps34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00142">
        <property type="entry name" value="PI3K_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51547">
        <property type="entry name" value="C2_PI3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="C2 PI3K-type" evidence="11">
        <location>
            <begin position="15"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="PIK helical" evidence="10">
        <location>
            <begin position="363"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="640"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="339"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="360"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA45863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="927" mass="104814" checksum="C2203E29BB2A5EE2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLC1</accession>
    <name>G4NLC1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_02958</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720748.1">
        <property type="nucleotide sequence ID" value="XM_003720700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLC1"/>
    <dbReference type="FunCoup" id="G4NLC1">
        <property type="interactions" value="17"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NLC1"/>
    <dbReference type="GeneID" id="2682511"/>
    <dbReference type="KEGG" id="mgr:MGG_02958"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02958"/>
    <dbReference type="eggNOG" id="KOG2238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006760_1_0_1"/>
    <dbReference type="InParanoid" id="G4NLC1"/>
    <dbReference type="OMA" id="AKKWSWS"/>
    <dbReference type="OrthoDB" id="26740at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21675">
        <property type="entry name" value="SMP_TEX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF19">
        <property type="entry name" value="NUCLEUS-VACUOLE JUNCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15413">
        <property type="entry name" value="PH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="295"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="520"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="783"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="565"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="602"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="662"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="679"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="819"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="859"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="920"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="971"/>
            <end position="992"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA46005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1015" mass="109981" checksum="7D514D7448055092" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLE3</accession>
    <name>G4NLE3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_02938</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720770.1">
        <property type="nucleotide sequence ID" value="XM_003720722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLE3"/>
    <dbReference type="SMR" id="G4NLE3"/>
    <dbReference type="FunCoup" id="G4NLE3">
        <property type="interactions" value="760"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NLE3"/>
    <dbReference type="GeneID" id="2682491"/>
    <dbReference type="KEGG" id="mgr:MGG_02938"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02938"/>
    <dbReference type="eggNOG" id="KOG1781">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076902_3_0_1"/>
    <dbReference type="InParanoid" id="G4NLE3"/>
    <dbReference type="OMA" id="PFVQQEE"/>
    <dbReference type="OrthoDB" id="274944at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01729">
        <property type="entry name" value="LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000043">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017132">
        <property type="entry name" value="Lsm7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF5">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="56"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA46027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="146" mass="15667" checksum="8A8832A21EE724F8" modified="2011-12-14" version="1">MADRPHRGGGGGGGNRGNYRGRGGGDRGGRGGRGGDHHHGGKNNDQQGERERPKKENILDLAKYMDKEVQVKFNGGREVIGTLKGYDALMNLVLDEVKETMRDEEGNESSRPLGLVVVRGTLLVAISPTDGSESIANPFLQQGDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G5EGX5</accession>
    <name>G5EGX5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pyruvate dehydrogenase E1 component subunit beta</fullName>
            <ecNumber evidence="10">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGCH7_ch7g117</name>
        <name evidence="13" type="ORF">MGG_10569</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15</strain>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">70-15</strain>
        </source>
    </reference>
    <reference evidence="13" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="10"/>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721383.1">
        <property type="nucleotide sequence ID" value="XM_003721335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EGX5"/>
    <dbReference type="SMR" id="G5EGX5"/>
    <dbReference type="FunCoup" id="G5EGX5">
        <property type="interactions" value="777"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EGX5"/>
    <dbReference type="GeneID" id="2682182"/>
    <dbReference type="KEGG" id="mgr:MGG_10569"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10569"/>
    <dbReference type="eggNOG" id="KOG0524">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012907_1_1_1"/>
    <dbReference type="OMA" id="WYANCPG"/>
    <dbReference type="OrthoDB" id="10266385at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000006">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027110">
        <property type="entry name" value="PDHB_mito-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006667">
        <property type="entry name" value="PRK09212.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008854">
        <property type="entry name" value="PRK11892.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624">
        <property type="entry name" value="DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624:SF96">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="9 10 13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="11">
        <location>
            <begin position="57"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EAQ70710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA46640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="383" mass="41690" checksum="0D7AAEB53F998F3E" modified="2011-12-14" version="1">MSRYLRPAVRMAATAARAPALRSSTGTSSLIGSQRAAAFRPAVSMQQRWASSGTKEYTVREALNEALVEELEANDKVFVMGEEVAQYNGAYKVTKGLLDRFGERRIIDTPITEMGFTGLAVGAALSGLHPVCEFMTYNFAMQSIDHIVNSAAKTLYMSGGIQPCNITFRGPNGFASGVGAQHSQDYSAWYGSIPGLKVVSPWSAEDAKGLLKAAIRDPNPVVVLENELMYGQSFPMSEAAQKDDFVIPFGKAKIERQGKDLTIVTLSRCVGQSLVAAENLKKKYGVEVEVINLRSIKPLDINAIVQSVKKTHRLMSVESGFPAFGVGSEILALTMEYAFDYLDAPAQRVTGADVPTPYAQKLEEMSFPTEQIIEEHAAKMLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHF2</accession>
    <name>G5EHF2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g867</name>
        <name evidence="3" type="ORF">MGG_03066</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720610.1">
        <property type="nucleotide sequence ID" value="XM_003720562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHF2"/>
    <dbReference type="GeneID" id="2682619"/>
    <dbReference type="KEGG" id="mgr:MGG_03066"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03066"/>
    <dbReference type="eggNOG" id="ENOG502SVSE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075611_0_0_1"/>
    <dbReference type="OMA" id="REEDKQW"/>
    <dbReference type="OrthoDB" id="4203030at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="254" mass="28282" checksum="5FA3C1881B3B4E95" modified="2011-12-14" version="1">MATAVLQQSGPRVFGNHGNIEALTAEDFETASIHSAAPSYVSEVPSYHTIPREATPAYSPPEQSSPPSYSFNSHRSQRRTATTASIDYYANNSSRPSLIPPADSVDEPTIGLPPVPTGPLPAIAPQLSAFRIPSWSSLAANNPNNRQYRNVAQRRASAAAVSSTRRLDISPSRMARLERVSELAEAEEQRRHRPLEDPYLVGEVAARRARAQRLARENGDEVLEMENRRWDLFLAQMRDFQPRNRRGNSSRRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHM3</accession>
    <name>G5EHM3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-Ig-H3/Fasciclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGCH7_ch7g645</name>
        <name evidence="5" type="ORF">MGG_02884</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15</strain>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720846.1">
        <property type="nucleotide sequence ID" value="XM_003720798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHM3"/>
    <dbReference type="SMR" id="G5EHM3"/>
    <dbReference type="STRING" id="242507.G5EHM3"/>
    <dbReference type="GeneID" id="2682437"/>
    <dbReference type="KEGG" id="mgr:MGG_02884"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02884"/>
    <dbReference type="eggNOG" id="KOG1218">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031281_2_2_1"/>
    <dbReference type="OMA" id="DIMFNGG"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="PHI-base" id="PHI:4231"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.180.10:FF:000032">
        <property type="entry name" value="Fasciclin domain-containing protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010834265" evidence="2">
        <location>
            <begin position="18"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="17"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="168"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EAQ71238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA46103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="349" mass="35849" checksum="8C4A781D7E07FDBF" modified="2011-12-14" version="1">MKFTITVSALFAACAAAQSLTEVLSKHESVSALNNLLSTQPALVSTLGSAKNITILAPNNEAITALTSDSANAAAIQKDSGLVPAILSYHVINGTYRGDAFTKEAKFLPTLLTNATYAQVMGGQKVEGKAAGQTVEFKSGLQKMSKVTEANIAFDGGVIHVIDSVLTLPPAAAPALTKLDLKSLAESLTKANLVKTVEELKDVTIFAPADSAFAKLSSTSSTLSVEQLSAVLTYHVVNGTVAYSTDLKDGQKVKTVNGQEVTVRIKNGEVMVGNAKVVTPDVLISNGVVHVIDNVLMPGGATTSQGSVSSGGAAARPSSPPASEGHFLTRPGSASFVVLMVGVAIITGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHR1</accession>
    <name>G5EHR1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g121</name>
        <name evidence="2" type="ORF">MGG_18055</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">70-15</strain>
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    <sequence length="84" mass="9473" checksum="A130AF928955AE7C" modified="2011-12-14" version="1">MSTRTYTVAADYVSLDDLLADVVREQRKTALSQTWHRGWLSWESWRLWLASRSSSSLDVDVEAAGWLVNNVDGLLSNDRAGNMA</sequence>
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    <accession>P56221</accession>
    <accession>A4QTI6</accession>
    <accession>G4N445</accession>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>PROTEIN SEQUENCE OF 95-106</scope>
        <scope>INDUCTION</scope>
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            <dbReference type="PubMed" id="8355286"/>
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        <scope>CRYSTALLIZATION</scope>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>ACTIVE SITE</scope>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>BIOPHYSICOCHEMICAL PROPERTIES</scope>
        <scope>ACTIVE SITE</scope>
        <scope>MUTAGENESIS OF TYR-30; ASP-31; TYR-50; HIS-85; HIS-110; SER-129 AND ASN-131</scope>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>ACTIVITY REGULATION</scope>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>ACTIVITY REGULATION</scope>
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                <person name="Basarab G.S."/>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>INHIBITOR-BINDING</scope>
        <scope>MUTAGENESIS OF PHE-53; MET-69; VAL-75; PHE-158 AND PHE-162</scope>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>MUTAGENESIS OF TYR-30; TYR-50; HIS-85; HIS-110 AND ASN-131</scope>
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            <dbReference type="PubMed" id="10882002"/>
            <dbReference type="DOI" id="10.1016/S0968-0896(00)00034-1"/>
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        <scope>ACTIVITY REGULATION</scope>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>BIOPHYSICOCHEMICAL PROPERTIES</scope>
        <scope>MUTAGENESIS OF PHE-53; HIS-110 AND ASN-131</scope>
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                <person name="Schwartz R.S."/>
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            <dbReference type="PubMed" id="12413868"/>
            <dbReference type="DOI" id="10.1016/S0968-0896(02)00272-9"/>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>ACTIVITY REGULATION</scope>
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        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>ACTIVITY REGULATION</scope>
        <scope>MUTAGENESIS OF VAL-75</scope>
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        <scope>ACTIVITY REGULATION</scope>
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        <scope>X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) IN COMPLEX WITH INHIBITOR</scope>
        <scope>SUBUNIT</scope>
        <scope>ACTIVE SITE</scope>
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            <dbReference type="DOI" id="10.1107/S0907444901017371"/>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS)</scope>
    </reference>
    <comment type="function">
        <text evidence="2 3 4 5 6 8 9 10 11 15 16 17 18">Scytalone dehydratase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene melanin, a bluish-green pigment and a structural component of the conidial wall (PubMed:9571787). Within the pathway, catalyzes the dehydration of scytalone as well as of vermelone (PubMed:10320327, PubMed:10386945, PubMed:10386946, PubMed:10636235, PubMed:10694394, PubMed:10913266, PubMed:11790103, PubMed:12413868, PubMed:15056895, PubMed:9466791, PubMed:9466792, PubMed:9539706, PubMed:9571787). Is also able to dehydrate the alternate substrate 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one (DDBO) to 5-hydroxy-4H-1-benzopyran-4-one (HBO) (PubMed:10320327, PubMed:10386945, PubMed:11790103, PubMed:9466791, PubMed:9466792).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3 4 5 6 8 9 10 11 15 16 17 18">
            <text>scytalone = 1,3,8-trihydroxynaphthalene + H2O</text>
            <dbReference type="Rhea" id="RHEA:24396"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16945"/>
            <dbReference type="ChEBI" id="CHEBI:18393"/>
            <dbReference type="EC" id="4.2.1.94"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="3 4 7 10 11 13">(N-phenoxypropyl)-carboxamides such as carpropamid and derivatives of norephedrine act as inhibitors of scytalone dehydratase activity.</text>
    </comment>
    <comment type="biophysicochemical properties">
        <kinetics>
            <KM evidence="2 15">15 uM for 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one (DDBO)</KM>
            <KM evidence="2">33 uM for scytalone</KM>
            <KM evidence="2 9">31 uM for vermelone</KM>
        </kinetics>
    </comment>
    <comment type="pathway">
        <text evidence="18">Pigment biosynthesis; melanin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotrimer (PubMed:7866745). Each subunit contains an active site, located in the central part of the hydrophobic core of the monomer, which functions independently (PubMed:7866745).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="12 18">Expression is induced in the stationary phase, when melanin synthesis occurs (PubMed:9571787). Expression is specifically induced during appressorium formation (PubMed:15378734).</text>
    </comment>
    <comment type="similarity">
        <text evidence="21">Belongs to the scytalone dehydratase family.</text>
    </comment>
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    <dbReference type="EMBL" id="AB004741">
        <property type="protein sequence ID" value="BAA34046.1"/>
        <property type="molecule type" value="mRNA"/>
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    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003712572.1">
        <property type="nucleotide sequence ID" value="XM_003712524.1"/>
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    <dbReference type="PDB" id="1IDP">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.45 A"/>
        <property type="chains" value="A/B/C=1-172"/>
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    <dbReference type="PDB" id="1STD">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="2.90 A"/>
        <property type="chains" value="A=1-172"/>
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    <dbReference type="PDB" id="2STD">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="2.10 A"/>
        <property type="chains" value="A=1-172"/>
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        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.65 A"/>
        <property type="chains" value="A/B/C=10-172"/>
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    <dbReference type="PDB" id="4STD">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="2.15 A"/>
        <property type="chains" value="A/B/C=10-172"/>
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    <dbReference type="PDB" id="5STD">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.95 A"/>
        <property type="chains" value="A/B/C=10-172"/>
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    <dbReference type="PDB" id="6STD">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.80 A"/>
        <property type="chains" value="A/B/C=10-172"/>
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    <dbReference type="PDB" id="7STD">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.80 A"/>
        <property type="chains" value="A/B/C=10-172"/>
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    <dbReference type="BindingDB" id="P56221"/>
    <dbReference type="ChEMBL" id="CHEMBL2578"/>
    <dbReference type="EnsemblFungi" id="MGG_05059T0">
        <property type="protein sequence ID" value="MGG_05059T0"/>
        <property type="gene ID" value="MGG_05059"/>
    </dbReference>
    <dbReference type="GeneID" id="2675492"/>
    <dbReference type="KEGG" id="mgr:MGG_05059"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05059"/>
    <dbReference type="eggNOG" id="ENOG502SNND">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101889_0_0_1"/>
    <dbReference type="InParanoid" id="P56221"/>
    <dbReference type="OMA" id="SACYEWA"/>
    <dbReference type="OrthoDB" id="5281072at2759"/>
    <dbReference type="BRENDA" id="4.2.1.94">
        <property type="organism ID" value="3152"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00785"/>
    <dbReference type="EvolutionaryTrace" id="P56221"/>
    <dbReference type="PRO" id="PR:P56221"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030411">
        <property type="term" value="F:scytalone dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042438">
        <property type="term" value="P:melanin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00531">
        <property type="entry name" value="NTF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004235">
        <property type="entry name" value="Scytalone_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049884">
        <property type="entry name" value="Scytalone_dh"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02982">
        <property type="entry name" value="Scytalone_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF024851">
        <property type="entry name" value="SCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0002">3D-structure</keyword>
    <keyword id="KW-0106">Calcium</keyword>
    <keyword id="KW-0903">Direct protein sequencing</keyword>
    <keyword id="KW-0967">Endosome</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0470">Melanin biosynthesis</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000097639" description="Scytalone dehydratase">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="active site" evidence="23">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="active site" evidence="23">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22 23 25">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="mutagenesis site" description="Results in a 9-fold decrease of activity with scytalone as the substrate and increases binding of salicylamide inhibitors." evidence="2 5">
        <original>Y</original>
        <variation>F</variation>
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Reduces catalysis 5000-fold and substrate affinity about 4-fold with scytalone as the substrate." evidence="2">
        <original>D</original>
        <variation>N</variation>
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Results in a 500-fold decrease of activity with scytalone as the substrate and increases binding of salicylamide inhibitors." evidence="2 5">
        <original>Y</original>
        <variation>F</variation>
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Leads to significantly higher relative substrate specificities (DDBO/vermelone)." evidence="9">
        <original>F</original>
        <variation>A</variation>
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Affects the binding of inhibitors and has significantly higher relative substrate specificities (DDBO/vermelone)." evidence="8 9">
        <original>F</original>
        <variation>L</variation>
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Affects the binding of inhibitors." evidence="8">
        <original>M</original>
        <variation>L</variation>
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Affects the binding of inhibitors and reduces more than 200-fold inhibition by carpropamid." evidence="8 11">
        <original>V</original>
        <variation>A</variation>
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Strongly reduces inhibition by carpropamid." evidence="13">
        <original>V</original>
        <variation>M</variation>
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Greatly decreases catalytic efficiency and decreases binding to salicylamide inhibitors." evidence="2 5">
        <original>H</original>
        <variation>N</variation>
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Causes a 250-fold decrease of activity and a 6-fold increase in Km with scytalone as the substrate, decreases binding of salicylamide inhibitors, and has significantly higher relative substrate specificities (DDBO/vermelone)." evidence="2 5 9">
        <original>H</original>
        <variation>N</variation>
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Results in a 80-fold decrease of activity and a 7-fold increase in Km with scytalone as the substrate." evidence="2">
        <original>S</original>
        <variation>A</variation>
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Results in a 120-fold decrease of activity and a 23-fold increase in Km with scytalone as the substrate." evidence="2">
        <original>S</original>
        <variation>T</variation>
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Decreases turnover by nearly 90-fold and increases Km 8-fold with scytalone as the substrate, decreases strongly binding of salicylamide inhibitors, and has significantly higher relative substrate specificities (DDBO/vermelone)." evidence="2 5 9">
        <original>N</original>
        <variation>A</variation>
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Affects the binding of inhibitors." evidence="8">
        <original>F</original>
        <variation>L</variation>
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="Affects the binding of inhibitors." evidence="8">
        <original>F</original>
        <variation>L</variation>
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="helix" evidence="26">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="helix" evidence="26">
        <location>
            <begin position="35"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="strand" evidence="26">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="helix" evidence="26">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="strand" evidence="26">
        <location>
            <begin position="57"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="helix" evidence="26">
        <location>
            <begin position="63"/>
            <end position="71"/>
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    </feature>
    <feature type="turn" evidence="26">
        <location>
            <begin position="73"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="strand" evidence="26">
        <location>
            <begin position="81"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="strand" evidence="26">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="strand" evidence="26">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="strand" evidence="26">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="strand" evidence="26">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="helix" evidence="27">
        <location>
            <begin position="158"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="helix" evidence="27">
        <location>
            <begin position="163"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="O14434"/>
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    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="10320327"/>
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    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="10386945"/>
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    <evidence type="ECO:0000269" key="4">
        <source>
            <dbReference type="PubMed" id="10386946"/>
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    <evidence type="ECO:0000269" key="5">
        <source>
            <dbReference type="PubMed" id="10636235"/>
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    </evidence>
    <evidence type="ECO:0000269" key="6">
        <source>
            <dbReference type="PubMed" id="10694394"/>
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    </evidence>
    <evidence type="ECO:0000269" key="7">
        <source>
            <dbReference type="PubMed" id="10882002"/>
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    </evidence>
    <evidence type="ECO:0000269" key="8">
        <source>
            <dbReference type="PubMed" id="10913266"/>
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    </evidence>
    <evidence type="ECO:0000269" key="9">
        <source>
            <dbReference type="PubMed" id="11790103"/>
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    </evidence>
    <evidence type="ECO:0000269" key="10">
        <source>
            <dbReference type="PubMed" id="12413868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="11">
        <source>
            <dbReference type="PubMed" id="15056895"/>
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    </evidence>
    <evidence type="ECO:0000269" key="12">
        <source>
            <dbReference type="PubMed" id="15378734"/>
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    <evidence type="ECO:0000269" key="13">
        <source>
            <dbReference type="PubMed" id="15382507"/>
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    <evidence type="ECO:0000269" key="14">
        <source>
            <dbReference type="PubMed" id="7866745"/>
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    <evidence type="ECO:0000269" key="15">
        <source>
            <dbReference type="PubMed" id="9466791"/>
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    </evidence>
    <evidence type="ECO:0000269" key="16">
        <source>
            <dbReference type="PubMed" id="9466792"/>
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    </evidence>
    <evidence type="ECO:0000269" key="17">
        <source>
            <dbReference type="PubMed" id="9539706"/>
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    </evidence>
    <evidence type="ECO:0000269" key="18">
        <source>
            <dbReference type="PubMed" id="9571787"/>
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    </evidence>
    <evidence type="ECO:0000303" key="19">
        <source>
            <dbReference type="PubMed" id="9539706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="20">
        <source>
            <dbReference type="PubMed" id="9571787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="21"/>
    <evidence type="ECO:0000305" key="22">
        <source>
            <dbReference type="PubMed" id="10382670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="23">
        <source>
            <dbReference type="PubMed" id="7866745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="24">
        <source>
            <dbReference type="PubMed" id="9665698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="25">
        <source>
            <dbReference type="PubMed" id="9922139"/>
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    </evidence>
    <evidence type="ECO:0007829" key="26">
        <source>
            <dbReference type="PDB" id="1IDP"/>
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    </evidence>
    <evidence type="ECO:0007829" key="27">
        <source>
            <dbReference type="PDB" id="3STD"/>
        </source>
    </evidence>
    <sequence length="172" mass="20250" checksum="2FA56296D5EE00DC" modified="1998-07-15" version="1">MGSQVQKSDEITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4J0</accession>
    <name>A0A151V4J0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_10278</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="JH165178">
        <property type="protein sequence ID" value="KYQ30503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846007.1">
        <property type="nucleotide sequence ID" value="XM_016990524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4J0"/>
    <dbReference type="SMR" id="A0A151V4J0"/>
    <dbReference type="GeneID" id="2681830"/>
    <dbReference type="KEGG" id="mgr:MGG_10278"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10278"/>
    <dbReference type="eggNOG" id="ENOG502SIF1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4J0"/>
    <dbReference type="OMA" id="GKCHLPW"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF5">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="329"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KYQ30503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="473" mass="51885" checksum="6CA9D466C6C3DF90" modified="2016-06-08" version="1">MAALDVIIIGGGLAGACLANGLLNKAKDLVNVDVYEMDKRDSQRDGYQIRLGSYALTGFRACLTDRQYADLLLSFGRSGGVVSSAPTIFNPKMELLLELGKFPAYTKSAPIGRARLRNMLQAPLLEHNMMHHGKTFVRYEILKAAEGSSSPEDRRIRVHFADGTSADCDVLISAEGSGSRINRQLGCNNIVENPETESGGILGKCHVPWSVLRELPRVLVEKGTIFTAGSGCRLFAAVYLPDKYNSQPEAMDEGKPSDYDESQSSLMVSFAWEGTPLPREVVKLPDPKAFMRQKMAEAGWHPEYAKLIDALEPDALQSVPLRQARDTPVDWRRRARADPAHAADPDVAHPRVWLLGDSFHPMLPSRGMGANNAICDSADVLGPLMELARQKKKLGHVPDEAARAQLAEYENAMIPRSMRWVKTSASQSLPDFDTFQGKIVIFGIRLVLAVVGTAVSIAKTFGWKPHDEAPELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4R9</accession>
    <name>A0A151V4R9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_10170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165202">
        <property type="protein sequence ID" value="KYQ30570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846074.1">
        <property type="nucleotide sequence ID" value="XM_016990477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4R9"/>
    <dbReference type="STRING" id="242507.A0A151V4R9"/>
    <dbReference type="GeneID" id="2681797"/>
    <dbReference type="KEGG" id="mgr:MGG_10170"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10170"/>
    <dbReference type="eggNOG" id="ENOG502RZZ4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4R9"/>
    <dbReference type="OMA" id="AAFHIWH"/>
    <dbReference type="OrthoDB" id="67965at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF15">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KYQ30570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29150" checksum="872FBA48FC2CCD72" modified="2016-06-08" version="1">MPHEQPVKIVERGVKRRSVAGTAVFLGLRSLDIPLQYKLLTGEWSLPLLSRIGLRPCAAALAPRTTTGIAAADRLGLTNPTLLLLAMAVGAAAKQCYWLTAICNEEFGPRASLIISAFNTAFNSINSMMLMTSLTSAANAWPGQVEGISAPMAVGAVLYVTGMYLEVVSEIQRRAFKENPKTKGKVCRTGLWRVARHINYGGYALWRSGYSLAAGGWIWGAMSAAFNLSAFIGSSIPELGSYMDKRYGREWQEYCGETRWVILPGFY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-06-10" modified="2026-01-28" version="115" xmlns="https://uniprot.org/uniprot">
    <accession>A4RE77</accession>
    <accession>G4NEN8</accession>
    <name>MYO1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Myosin-1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Class I unconventional myosin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Type I myosin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">MYO1</name>
        <name type="ORF">MGG_00748</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The myosin motor domain displays actin-stimulated ATPase activity and generates a mechanochemical force.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The tail domain participates in molecular interactions that specify the role of the motor domain (By similarity). It is composed of several tail homology (TH) domains, namely a putative phospholipid-binding myosin tail domain (also named TH1), an Ala- and Pro-rich domain (TH2), followed by an SH3 domain and a C-terminal acidic domain (TH3).</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718252.1">
        <property type="nucleotide sequence ID" value="XM_003718204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RE77"/>
    <dbReference type="SMR" id="A4RE77"/>
    <dbReference type="FunCoup" id="A4RE77">
        <property type="interactions" value="313"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RE77"/>
    <dbReference type="EnsemblFungi" id="MGG_00748T0">
        <property type="protein sequence ID" value="MGG_00748T0"/>
        <property type="gene ID" value="MGG_00748"/>
    </dbReference>
    <dbReference type="GeneID" id="2674396"/>
    <dbReference type="KEGG" id="mgr:MGG_00748"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00748"/>
    <dbReference type="eggNOG" id="KOG0162">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000192_7_6_1"/>
    <dbReference type="InParanoid" id="A4RE77"/>
    <dbReference type="OMA" id="PPEEYQM"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="PHI-base" id="PHI:11778"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01378">
        <property type="entry name" value="MYSc_Myo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11858">
        <property type="entry name" value="SH3_Myosin-I_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.4820:FF:000004">
        <property type="entry name" value="Myosin IE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.530:FF:000007">
        <property type="entry name" value="Myosin IE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035535">
        <property type="entry name" value="Fungal_myosin-I_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010926">
        <property type="entry name" value="Myosin_TH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036072">
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    <keyword id="KW-0067">ATP-binding</keyword>
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    <keyword id="KW-0206">Cytoskeleton</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0505">Motor protein</keyword>
    <keyword id="KW-0518">Myosin</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
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    <keyword id="KW-0728">SH3 domain</keyword>
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            <begin position="1"/>
            <end position="1212"/>
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            <begin position="41"/>
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            <begin position="719"/>
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        <location>
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            <begin position="1053"/>
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        <location>
            <begin position="1171"/>
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    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="134"/>
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        <ligand>
            <name>ATP</name>
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    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
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        <source>
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        <source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000305" key="7"/>
    <sequence length="1212" mass="134333" checksum="487EA59F5A96028D" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-07-10" modified="2025-06-18" version="99" xmlns="https://uniprot.org/uniprot">
    <accession>A4RGD1</accession>
    <accession>G4NEI8</accession>
    <name>RRP3_PYRO7</name>
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        <recommendedName>
            <fullName evidence="5">ATP-dependent rRNA helicase RRP3</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
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        <name evidence="1" type="primary">RRP3</name>
        <name type="ORF">MGG_17539</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
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        <text evidence="1">ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.</text>
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            <text>ATP + H2O = ADP + phosphate + H(+)</text>
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            <dbReference type="ChEBI" id="CHEBI:43474"/>
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        <text evidence="1">Interacts with the SSU processome.</text>
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        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
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        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
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    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.</text>
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        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="EHA49465" version="1"/>
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        <text>Extended N-terminus.</text>
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        <property type="entry name" value="Q_MOTIF"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
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            <begin position="1"/>
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        <location>
            <begin position="141"/>
            <end position="312"/>
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    </feature>
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        <location>
            <begin position="336"/>
            <end position="486"/>
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        <location>
            <begin position="1"/>
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        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEAD box" evidence="5">
        <location>
            <begin position="260"/>
            <end position="263"/>
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    </feature>
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        <location>
            <begin position="1"/>
            <end position="11"/>
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    </feature>
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        <location>
            <begin position="34"/>
            <end position="47"/>
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    </feature>
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        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
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            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
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        </location>
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    <feature type="binding site" evidence="2">
        <location>
            <begin position="154"/>
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        <ligand>
            <name>ATP</name>
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        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="P38712"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00541"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00542"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKT7</accession>
    <name>G4MKT7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709389.1">
        <property type="nucleotide sequence ID" value="XM_003709341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKT7"/>
    <dbReference type="SMR" id="G4MKT7"/>
    <dbReference type="STRING" id="242507.G4MKT7"/>
    <dbReference type="GeneID" id="2684855"/>
    <dbReference type="KEGG" id="mgr:MGG_06682"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06682"/>
    <dbReference type="eggNOG" id="KOG1208">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_44_4_1"/>
    <dbReference type="InParanoid" id="G4MKT7"/>
    <dbReference type="OMA" id="AMYATSK"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF22">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE PHMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="349" mass="37991" checksum="21278C88DE882DDF" modified="2011-12-14" version="1">MSAVVMTLKQKLFVQPMAAPDSFKGKKALVTGGTAGLGLATAIHLAQLGASTIAITCRDASRGESAKKKIEEAAGSSNVTVKVLELDMGRYPSVVAFTETVKKEFATEGGLDWICLNAGVHNASWEQSPEGWDMVIQVNVLSTVLISLLLLPWLKELRSQRQSPAHLTIVSSGMHMSTNISRWEKIAGQDGLLKHFSAKENWPGAAGQYGNSKLLLQYCVHELSQQALDAQGKPDLIINTCCPGMVWTEITRTLKEKHFILRAVEPLVMTLVAQTPEVGSRTYLKAGLTTEADHSKFITNYLADDAYVKKSKPVITSETAQKVQRLAWAEVTQELTSKVPSVSQVLTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML11</accession>
    <name>G4ML11_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="3 11">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_08622</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17 18">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the NDK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="3 11"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711050.1">
        <property type="nucleotide sequence ID" value="XM_003711002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML11"/>
    <dbReference type="SMR" id="G4ML11"/>
    <dbReference type="FunCoup" id="G4ML11">
        <property type="interactions" value="856"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ML11"/>
    <dbReference type="GeneID" id="2679051"/>
    <dbReference type="KEGG" id="mgr:MGG_08622"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08622"/>
    <dbReference type="eggNOG" id="KOG0888">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060216_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML11"/>
    <dbReference type="OMA" id="QHYGEHK"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000002">
        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="14">
        <location>
            <begin position="87"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="9">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA58438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="237" mass="25891" checksum="D07CE70F8E0BF732" modified="2011-12-14" version="1">MASPDSQPKPKPSSNGATTGDPAIKLGHQQRQKIFTPPNFALLLCLLLSLVNFYHLQKPGRASVIYVQEPSTPIPPTIYKNTAKMSTEQTFIAIKPDGVQRGLVGPIISRFEQRGYKLVAIKLVTPGKAHLEQHYADLKDKPFFAGLVEYMNSGPIAAMVWEGRDAVKTGRTLLGATNPLASAPGTIRGDYAIDVGRNVCHGSDSVENAKKEIALWFKEGEVVSYQASQASWIYEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLF2</accession>
    <name>G4MLF2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08653</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711085.1">
        <property type="nucleotide sequence ID" value="XM_003711037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLF2"/>
    <dbReference type="GeneID" id="2678895"/>
    <dbReference type="KEGG" id="mgr:MGG_08653"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08653"/>
    <dbReference type="eggNOG" id="ENOG502RU0H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055467_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLF2"/>
    <dbReference type="OMA" id="ITNDSCW"/>
    <dbReference type="OrthoDB" id="444631at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF129">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="7">
        <location>
            <begin position="82"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA58473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="420" mass="47172" checksum="D0C6D6D3D1D461A7" modified="2011-12-14" version="1">MVLNSTSRSAFFGQPPKTDRDFNIVRGIYRMAGVNDTLFSPSNGVYYAARVPPNYVHESKQTEIIVGMAVIIFVMLATTGARLIFKLQGYGTRFGMDDWVIIPAVCLAVTYPMLQIYMVVELGAGQHTWENTYEDYSRLAWMLETCTVLFFATVALIKISIALFVRRLAACVCKGWRIALDVFLATLVMYLVAAVLWNVLVCNPTRALWDVEFAGTLRTPPKCGSLVLMSKVLSLVHVFQGVTLLITPVVILWKIPMDVAKKLRLFIIWWFGAVTVTGGLLQQLAPSRSNGDIFYDHTTSLAWTSLDLTMGIITASLPTLDTAISSGWKSFRSRMSSLCEEPKVKTKEISWPKPIPPDLERDAGVPMGRTESTEFILADRGDVLEMHLVRPREGSTTYEFFELYQGDEKRPESAIHRPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLP5</accession>
    <name>G4MLP5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709490.1">
        <property type="nucleotide sequence ID" value="XM_003709442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLP5"/>
    <dbReference type="STRING" id="242507.G4MLP5"/>
    <dbReference type="GeneID" id="2684946"/>
    <dbReference type="KEGG" id="mgr:MGG_06773"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06773"/>
    <dbReference type="eggNOG" id="ENOG502T4WR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016898_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLP5"/>
    <dbReference type="OMA" id="CSHEACP"/>
    <dbReference type="OrthoDB" id="5245679at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465101" evidence="2">
        <location>
            <begin position="20"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="530"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="623"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="763"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="819" mass="78743" checksum="EB93D1E92033BA62" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLQ9</accession>
    <name>G4MLQ9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_05439</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003710251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLQ9"/>
    <dbReference type="STRING" id="242507.G4MLQ9"/>
    <dbReference type="GeneID" id="2675956"/>
    <dbReference type="KEGG" id="mgr:MGG_05439"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05439"/>
    <dbReference type="eggNOG" id="KOG3053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026793_1_0_1"/>
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    <dbReference type="OrthoDB" id="5817083at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
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    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46283">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="9">
        <location>
            <begin position="24"/>
            <end position="86"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_16387"/>
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    <dbReference type="InParanoid" id="G4MM91"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MML5</accession>
    <name>G4MML5_PYRO7</name>
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        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
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    <organism evidence="2 3">
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA57787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003710351.1"/>
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    <dbReference type="SMR" id="G4MML5"/>
    <dbReference type="STRING" id="242507.G4MML5"/>
    <dbReference type="GeneID" id="5051509"/>
    <dbReference type="KEGG" id="mgr:MGG_13106"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13106"/>
    <dbReference type="eggNOG" id="ENOG502S090">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="InParanoid" id="G4MML5"/>
    <dbReference type="OMA" id="LWVHQLQ"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF263">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="258" mass="29762" checksum="AF4A4ECCA50EB4CA" modified="2011-12-14" version="1">MAAYGDFHLVYWPSIPGRAEHIRLALELVGATYTDTAHQENAMDLMFSLMRNENNKLIAGVDCSTSPPYYATPALRHGQLLLSQTPNILMYLGERFPAQLVPEGCSKWIVNGLVLTALDGLSNEPHDCHHPVSSSLYYEDQKAEALRKSREYVKVRLPLFLDYFQRVLDSESSGDGPWLHRGRLTCADLVLFQCLDGVMFMFPKAMDKFKQSGRYDGLWRLYEAVRETDRIKKFLESERRQKYSNGIYRYYEELDIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMM3</accession>
    <name>G4MMM3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent Zn protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710407.1">
        <property type="nucleotide sequence ID" value="XM_003710359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMM3"/>
    <dbReference type="SMR" id="G4MMM3"/>
    <dbReference type="STRING" id="242507.G4MMM3"/>
    <dbReference type="GeneID" id="12986318"/>
    <dbReference type="KEGG" id="mgr:MGG_16395"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16395"/>
    <dbReference type="eggNOG" id="KOG0732">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025506_1_0_1"/>
    <dbReference type="InParanoid" id="G4MMM3"/>
    <dbReference type="OMA" id="EVWVFDQ"/>
    <dbReference type="OrthoDB" id="2115716at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF132">
        <property type="entry name" value="ATP-DEPENDENT ZN PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="2">
        <location>
            <begin position="231"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="477" mass="53533" checksum="154C0C646F64AFBE" modified="2011-12-14" version="1">MSSSDSQHGGRGGPTRTFFDHSSAARVSTDTVVAKSIREAYPQLELIIVPAQTTNLFTYAQAGNAKLTPIQDEANELLPSSLSWEIYVAPGKRIDGSRGGLVQRPLFGKYAYTWQDTEFILYYVEGRDGQSAYPTTNNFYLLASPADRGKAQSLLVAAGFWSQELHDEVLVFDGGYWNKSRELFNSIRKASWDNVILDPSMKQALIDDHMSFFKSRGQYEKLKVPWKRGIIYYGPPGNGKTVSIKATMNMLYKLKDPVPTLYVRSLVSWMGPEAALSMIFSGARAMAPCYLVFEDLDSIVNDSVRSYFLNEVDGLKNNDGIFMIGSTNHLERLDPGISKRPSRFDRKYLFPNPSRDQRVAYCHFWQGKLADNKDIEFPDSLCGAVADKTDKFSFAYIQEAFVASLLAIARASKQADEDDWVSVATPGTEDSDFESDDGYDDDDVKNLVLYKEMMKQIKILRDSIDSDDQALAKVELC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMP1</accession>
    <name>G4MMP1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF895 domain membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_05553</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710425.1">
        <property type="nucleotide sequence ID" value="XM_003710377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMP1"/>
    <dbReference type="GeneID" id="2675896"/>
    <dbReference type="KEGG" id="mgr:MGG_05553"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05553"/>
    <dbReference type="eggNOG" id="KOG3098">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030884_2_0_1"/>
    <dbReference type="InParanoid" id="G4MMP1"/>
    <dbReference type="OMA" id="AWWLWAT"/>
    <dbReference type="OrthoDB" id="196103at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF19">
        <property type="entry name" value="DUF895 DOMAIN MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA57813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="53149" checksum="011CD51D12D76DEC" modified="2011-12-14" version="1">MSHHESDQEPPKDQQYPVKWYRSTFTNVTILGLCNLAAPGIWGAMNSLGAGGAARPELINAANALTFCLMVVSCLFSSAIVRFIGIKGALIFGTLGYAPYAAGLYTNNRYGNEWFVLLGAALCGISAGVFWMAEAAIAIAYPEPWNRGRAIGYWLTYRLSGQILGGAINLGLNADRNGAGQVSYTVFLVFIAIQSAGPLIAFLLSPPAKVQRKDGKRVQLAITQNWWVEIKTTAKLFFTPKFLLLVLWIGQAVFAEAVFFTYIALWFSVRSRALASFLSGILAVTAGNGLGYWLDSTRFSLKVRSRASFWVIAIFQGAWWTWATVNVTRFHRTRPTYDWVDDDFGQGFAVFLLLTIGFQLNYMFFLDPKLTLHSNPRYFFIHNLSQDEPDIIRYAALLRGTESAWQALSYGLSSLTIFGEVGGVYMNFGMWAVSIYPAWLVLRHFGVHKSTGVEAISHSPAGDKVVDSSVEDHTIKALGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4MND2</accession>
    <name>G4MND2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Adenylate kinase isoenzyme 6 homolog</fullName>
            <shortName evidence="10">AK6</shortName>
            <ecNumber evidence="10">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Dual activity adenylate kinase/ATPase</fullName>
            <shortName evidence="10">AK/ATPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_16212</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Interacts with small ribosomal subunit protein uS11. Not a structural component of 43S pre-ribosomes, but transiently interacts with them by binding to uS11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylate kinase family. AK6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="10"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709658.1">
        <property type="nucleotide sequence ID" value="XM_003709610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MND2"/>
    <dbReference type="SMR" id="G4MND2"/>
    <dbReference type="FunCoup" id="G4MND2">
        <property type="interactions" value="813"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MND2"/>
    <dbReference type="GeneID" id="12985231"/>
    <dbReference type="KEGG" id="mgr:MGG_16212"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16212"/>
    <dbReference type="eggNOG" id="KOG3347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079096_3_1_1"/>
    <dbReference type="InParanoid" id="G4MND2"/>
    <dbReference type="OMA" id="QCEIFGT"/>
    <dbReference type="OrthoDB" id="10251185at2759"/>
    <dbReference type="PHI-base" id="PHI:9951"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000372">
        <property type="entry name" value="Adenylate kinase isoenzyme 6 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00039">
        <property type="entry name" value="Adenylate_kinase_AK6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020618">
        <property type="entry name" value="Adenyl_kinase_AK6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595:SF0">
        <property type="entry name" value="ADENYLATE KINASE ISOENZYME 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595">
        <property type="entry name" value="POS9-ACTIVATING FACTOR FAP7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13238">
        <property type="entry name" value="AAA_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMPbind" evidence="10">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="10">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA57046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="175" mass="19924" checksum="DBB99E288187D8C8" modified="2011-12-14" version="1">MATRSLPNIIVTGTPGTGKTTHCETLAQRTGLRHISVTHIVKDKECHEGWDEEYQSWIVDEDKLLDAIEDDAKAGGCIIDWHACDLFPKSWIDLVVVLRADSATHYDRLKARNYPENKLQENLDSEIMEVLLQEARDAYDAEIVVELQSNTTDEMEANVDRIEAWLSQWKKDNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MND4</accession>
    <name>G4MND4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709660.1">
        <property type="nucleotide sequence ID" value="XM_003709612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MND4"/>
    <dbReference type="GeneID" id="12985233"/>
    <dbReference type="KEGG" id="mgr:MGG_16214"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16214"/>
    <dbReference type="HOGENOM" id="CLU_3014643_0_0_1"/>
    <dbReference type="InParanoid" id="G4MND4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="56" mass="6311" checksum="D90241603347E93E" modified="2011-12-14" version="1">MTEPRVMKGGGTGARDFDPQKRRRRRFPPEDVLLIIFAAKASSKWRNGVLVARLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNL9</accession>
    <name>G4MNL9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710537.1">
        <property type="nucleotide sequence ID" value="XM_003710489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNL9"/>
    <dbReference type="SMR" id="G4MNL9"/>
    <dbReference type="GeneID" id="2676052"/>
    <dbReference type="KEGG" id="mgr:MGG_05645"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05645"/>
    <dbReference type="HOGENOM" id="CLU_1384401_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNL9"/>
    <dbReference type="OrthoDB" id="5238708at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="197" mass="21770" checksum="C3A543BCEA7ECE05" modified="2011-12-14" version="1">MNDPFYMWFLTGGTAHNIPANTTRVIEMARERNDAAAAAKEYATALKGAKAELKSSKKELKAGFESTSKELDAAHKAEWGSKPKDKRKWLNARRQQQQQQQQQQQQQQMDIDITAEAAVAQESRLLSREPPATAATTSADDGTVPEVPSAVDQRAAEQARLDMRLSELYERATQAMADLRAILDSPEIVQRGTQASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNN0</accession>
    <name>G4MNN0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kelch repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710548.1">
        <property type="nucleotide sequence ID" value="XM_003710500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNN0"/>
    <dbReference type="STRING" id="242507.G4MNN0"/>
    <dbReference type="GeneID" id="2676021"/>
    <dbReference type="KEGG" id="mgr:MGG_05655"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05655"/>
    <dbReference type="HOGENOM" id="CLU_776275_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNN0"/>
    <dbReference type="OMA" id="WRDAIEI"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="39280" checksum="D89B62F23CCCCFBA" modified="2011-12-14" version="1">MDVCRREEILRISDFRRLKRWFQTRDYTSWILISHSPKILLGKNATLALSLNEKWKSDDITLDTLNRGGLLARDAVHTNARWASEGMPGNAQSYKIFNWGGKARYKDDDPRYRAPPPLIRLTPSRVGTMPATTEGGWAVVAKPLNTPETILRTDKGARTTCKGVGYLLGGVTPYSKGEDAIPGPGDAGPGAHSLPEPDRTGLWLPPPALSPRNLSKWRRSAIRTWGLVQIDRVYMYDIATEKLYMQPATGGGVDGTPEVRRSPCAVAAGSHSGGTYEVVVFVGSDKGEVSSDVHVVTIPGFQWFRVPNTDKENKPMDGHQCTVVGDGQRQMLSLGGNVDGVDPWRDAIEILDMTELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNQ7</accession>
    <name>G4MNQ7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_02115</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_02115"/>
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    <dbReference type="OrthoDB" id="191139at2759"/>
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        <property type="component" value="Chromosome 1"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA56273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="403" mass="42967" checksum="1F52D8F5462ABBA6" modified="2011-12-14" version="1">MAESESPFRSSNTSIASSVESTGSQPSTSSTTTGDQSGLQGSSSTGILDASSLRRNRSYIDVGSRSLRPDKVGRSLPDSASGSTTRSHLGVDDGGGKLPDETEVYFLYMDLANLDSVRDAASRFLACVDRLDILILNAAEVSVPSGVTAQGYERHFGTNHLGHALLIKLLMRLLVRTATCDSVGSDVRVICVSSFAHRFTPPEGIDFDSLKPDPSSFHDSASATGSTTNITQSDTNQPGQQGRDGGGGGRPATSGSSQRPTLRRRRSSHTGSGPSSRLLYGQSKLANILYARELAERCPLFTTVSIHPGIAKSEGNWRRGGSRVVGSGAVVERFEQWIVPVFGASIDEGAKNHLWAATGRGISNGQYYEPVGVPARPSGVGDDRVLSWKLWEWTQRELAGYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPF0</accession>
    <name>G4MPF0_PYRO7</name>
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        <submittedName>
            <fullName evidence="10">Zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_09200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EHA57203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003709767.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="2680185"/>
    <dbReference type="KEGG" id="mgr:MGG_09200"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09200"/>
    <dbReference type="eggNOG" id="ENOG502SB6R">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017895_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPF0"/>
    <dbReference type="OMA" id="HPECGKT"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
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            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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            <end position="129"/>
        </location>
    </feature>
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        </location>
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    </feature>
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    </feature>
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            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA57203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="607" mass="67098" checksum="1D0EDB506C86C2F9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPV7</accession>
    <name>G4MPV7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09241</name>
    </gene>
    <organism evidence="3 4">
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        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709866.1">
        <property type="nucleotide sequence ID" value="XM_003709818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPV7"/>
    <dbReference type="GeneID" id="2680230"/>
    <dbReference type="KEGG" id="mgr:MGG_09241"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09241"/>
    <dbReference type="HOGENOM" id="CLU_885880_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPV7"/>
    <dbReference type="OrthoDB" id="10553647at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="33876" checksum="06A6343E28781355" modified="2011-12-14" version="1">MAAILVASAAPRAFDFDTSKPTYGTDIFLVCLLAFVFVGGLAGLVLVDLRRKWRGDSFESAATASAYAPVSAAVAKAIPKPAGSCRAGWSLSKTSTTDALPTIGLPKMEGISYSPTQTPSRPSLQQGSTEFEVDVSDGGEVSSGSTTEVASSVYEKSAGRKNSGLKSLQTPGYRDETLEFGVNGLPGPNRTRTCTCTCTRTCTTKAQVQEFLDKQKSSKDKFEPVWSTPRDVVQQSEDRTVLWLVDPERPGSRPRKIHITRTCTRTCTTKGTMDSVLVFFFFHFVASVGVSIALAFFMVAIINADWGVESEDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPY7</accession>
    <name>G4MPY7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_13178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710687.1">
        <property type="nucleotide sequence ID" value="XM_003710639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPY7"/>
    <dbReference type="GeneID" id="5051579"/>
    <dbReference type="KEGG" id="mgr:MGG_13178"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13178"/>
    <dbReference type="eggNOG" id="ENOG502SVX1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_645688_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPY7"/>
    <dbReference type="OMA" id="VENNYHA"/>
    <dbReference type="OrthoDB" id="2394218at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="10"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="425" mass="44702" checksum="1F7F818EE9139D78" modified="2011-12-14" version="1">MPRTVLCAARILPRAELPSPGQSSQGPSTGAAAGSPQNGTSQPGIPQPGSSPNGSTTTTTSPTGNAQTTEIAHPPPGVNLEGAVGIAMGCLVAGILIGLAAMILFHRRRTYGTRRRAPEAPVARQLPVQAQTPQKLLPWHKDMFELGPFLLDSSSDKDIAGMLDEAGQLIEQHVENNYHAKPVSTSPHELTKALQGLGVEGVDGKGSSVSAATLTSLALESGTRRLALRHLLSLVIFSSMDLDRIRRQKIPGHPPSILPAPMVAFVQAQPGPGLYENREATARAATQWRVLAAYLMNGKRCDRTALEADPEALKAQAAALAQALDAVLAPFARPGQVENLVAVILESARLGYVLVSQPNDWRFEHSRSGGGSSSSSGGGNENGKKVDAGGLELVVCAGLSRVSCGDQGNLRLRRVRVPVVERIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ29</accession>
    <name>G4MQ29_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709034.1">
        <property type="nucleotide sequence ID" value="XM_003708986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQ29"/>
    <dbReference type="GeneID" id="12984316"/>
    <dbReference type="KEGG" id="mgr:MGG_16081"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16081"/>
    <dbReference type="HOGENOM" id="CLU_980297_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQ29"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="284" mass="30738" checksum="457F6A04E2FD935D" modified="2011-12-14" version="1">MITTHRKCCWSGVMVQRQGYPPNKVGKCLAYLQLSAHAPCNYDTQNTSEILPSDRMTLPVGIHSLLIISVLAVRNKRNLCHAKFNKSRQEEAQIGQVARTGPRPKSCTGARRCVGKDWITGDEQAPWPAVASQALGEGVHLQVHPPPPSPSIADPTLPLLSHDNARDSGPGLQQNQTGNSAIWAGENLATHADCVRLKISTVMLAALQDRRTVGYAEGPERCIESSNTASGGRAERPWFGKGQAEVDVTLTPAWGKRKGTVTADLQPILEEINGRPHLNGLVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ41</accession>
    <name>G4MQ41_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709046.1">
        <property type="nucleotide sequence ID" value="XM_003708998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQ41"/>
    <dbReference type="GeneID" id="12984335"/>
    <dbReference type="KEGG" id="mgr:MGG_16084"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16084"/>
    <dbReference type="HOGENOM" id="CLU_1635734_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQ41"/>
    <dbReference type="OrthoDB" id="5182123at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="162" mass="16727" checksum="96954C8665EF5271" modified="2011-12-14" version="1">MSTSIPNIHPRCAQAKKVASNHKTLAPLAILLSLGAAQFDVQCDQTQLFSAPRDAFDAFIDLIPDGEWQDDDGVGFGRNEGGSLICASASPCPGCSVTGEQVRGMLRQGYDDCDIGGSGNDAGEGRFWQYRVDDGDTSILAGGGPCPGTFGVPGTSVAVTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRB7</accession>
    <name>G4MRB7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_04680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710854.1">
        <property type="nucleotide sequence ID" value="XM_003710806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRB7"/>
    <dbReference type="SMR" id="G4MRB7"/>
    <dbReference type="GeneID" id="2678127"/>
    <dbReference type="KEGG" id="mgr:MGG_04680"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04680"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_3_2_1"/>
    <dbReference type="InParanoid" id="G4MRB7"/>
    <dbReference type="OMA" id="WACAVMT"/>
    <dbReference type="OrthoDB" id="433474at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="202"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA58242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="457" mass="49426" checksum="F14B5892040991F9" modified="2011-12-14" version="1">MGSPSPGTATSPPEDGDTADDYVNPLDQSPRWALATRAYAIRSGASLGFGISNAWAPPELAPVKVIWLDALLGDWKAKRAIRVDVWEPPSQPNTDKPDFPSTSQSSASDLLALAAPNVVVKTPTDEIDDNASIKSGCSSALSSSGRSSSSKLGTPKRPRIYKVASNLSSRSSRSIASIRSRLSRSNTASGLSLDSIPKRPVVINFHGGGFVVGEGTDDSRWCSAVAKSLNAVVFSVSYRLAPGYPFPNAVEDCASAIVQICSQDMASQYAIDTSRVILSGFSAGGNLALASWVALQDPARWGYESVLPSPPLEMAGLALFYPLLDWTIARDTKRQRCERPDLTLPKGLTDLFDASYIYPPLQSSKRDDPRLSPGLMSDRMLQQLPPVHFCLCEYDMLLAEGLTFTERLKSHGRIVETRVVKGEKHAWDKPPLWAPKENAAVEYEAAIESLKTWVGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRG7</accession>
    <name>G4MRG7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Guanine nucleotide exchange factor LTE1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_02419</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709206.1">
        <property type="nucleotide sequence ID" value="XM_003709158.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MRG7"/>
    <dbReference type="FunCoup" id="G4MRG7">
        <property type="interactions" value="167"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRG7"/>
    <dbReference type="GeneID" id="2681516"/>
    <dbReference type="KEGG" id="mgr:MGG_02419"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02419"/>
    <dbReference type="eggNOG" id="KOG3417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001471_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRG7"/>
    <dbReference type="OMA" id="ICNYATM"/>
    <dbReference type="OrthoDB" id="10254377at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF363">
        <property type="entry name" value="PROTEIN SON OF SEVENLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
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        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="PROSITE" id="PS50212"/>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1863" mass="204565" checksum="FA10884F645540A0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRS5</accession>
    <name>G4MRS5_PYRO7</name>
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        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
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        <name evidence="9" type="ORF">MGG_04590</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
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            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
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        </reaction>
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        <text evidence="1 5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
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    <dbReference type="InParanoid" id="G4MRS5"/>
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    <dbReference type="GO" id="GO:0005829">
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="PRK00174.1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA58290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="726" mass="79553" checksum="CC3D1A5286E15598" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS64</accession>
    <name>G4MS64_PYRO7</name>
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            <fullName evidence="4">phosphoinositide 5-phosphatase</fullName>
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    <gene>
        <name evidence="11" type="ORF">MGG_04549</name>
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    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptojanin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.36" evidence="4"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003710886.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_04549"/>
    <dbReference type="eggNOG" id="KOG0566">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_003016_2_1_1"/>
    <dbReference type="InParanoid" id="G4MS64"/>
    <dbReference type="OMA" id="HPCHELR"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0043813">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09090">
        <property type="entry name" value="INPP5c_ScInp51p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000029">
        <property type="entry name" value="Inositol polyphosphate 5-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
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    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
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    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF257">
        <property type="entry name" value="PHOSPHOINOSITIDE 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SAC" evidence="10">
        <location>
            <begin position="213"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="996"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1100"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1042"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1076"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1125"/>
            <end position="1165"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1215"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1353"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1378"/>
            <end position="1392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA58322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1408" mass="155631" checksum="E4875C10F15E04C9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSF2</accession>
    <name>G4MSF2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">White collar 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_04521</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="XM_003713523.1"/>
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        <property type="component" value="Chromosome 2"/>
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        <property type="evidence" value="ECO:0007669"/>
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    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
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        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172:SF24">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172">
        <property type="entry name" value="OS01G0976800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="196"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="9">
        <location>
            <begin position="494"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="72"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="334"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="532"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="556" mass="60627" checksum="B47A823D744884EC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSH5</accession>
    <name>G4MSH5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_15700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714398.1">
        <property type="nucleotide sequence ID" value="XM_003714350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSH5"/>
    <dbReference type="SMR" id="G4MSH5"/>
    <dbReference type="GeneID" id="12984653"/>
    <dbReference type="KEGG" id="mgr:MGG_15700"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15700"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_1_1"/>
    <dbReference type="InParanoid" id="G4MSH5"/>
    <dbReference type="OMA" id="WGSLCCI"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000180">
        <property type="entry name" value="MFS monosaccharide transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF61">
        <property type="entry name" value="HIGH AFFINITY GLUCOSE TRANSPORTER RGT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="25"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="550" mass="59650" checksum="55F36955BEC5CC42" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2025-04-09" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSY9</accession>
    <name>MTA1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N6-methyladenosine RNA methyltransferase MTA1</fullName>
            <ecNumber evidence="3">2.1.1.348</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">M6A writer MTA1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MTA1</name>
        <name evidence="4" type="synonym">IME4</name>
        <name type="ORF">MGG_01492</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2019" name="FEMS Microbiol. Lett." volume="366" first="0" last="0">
            <title>N6-methyladenosine RNA methylation is involved in virulence of the rice blast fungus Pyricularia oryzae (syn. Magnaporthe oryzae).</title>
            <authorList>
                <person name="Shi Y."/>
                <person name="Wang H."/>
                <person name="Wang J."/>
                <person name="Liu X."/>
                <person name="Lin F."/>
                <person name="Lu J."/>
            </authorList>
            <dbReference type="PubMed" id="30535195"/>
            <dbReference type="DOI" id="10.1093/femsle/fny286"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2022" name="New Phytol." volume="235" first="247" last="262">
            <title>MTA1-mediated RNA m6 A modification regulates autophagy and is required for infection of the rice blast fungus.</title>
            <authorList>
                <person name="Ren Z."/>
                <person name="Tang B."/>
                <person name="Xing J."/>
                <person name="Liu C."/>
                <person name="Cai X."/>
                <person name="Hendy A."/>
                <person name="Kamran M."/>
                <person name="Liu H."/>
                <person name="Zheng L."/>
                <person name="Huang J."/>
                <person name="Chen X.L."/>
            </authorList>
            <dbReference type="PubMed" id="35338654"/>
            <dbReference type="DOI" id="10.1111/nph.18117"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="2 3">N6-methyladenosine RNA methyltransferase that plays a crucial role in fungal phenotypic traits, virulence, and stress tolerance (PubMed:35338654). Mediates the methylation of mRNAs to produce N6-methyladenosine (m6A)-containing mRNAs (PubMed:30535195, PubMed:35338654). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing (PubMed:35338654). Required for appressorium turgor pressure and regulates autophagosome formation during appressorium formation stage (PubMed:35338654). Specifically, mediates the stability of ATG8 mRNA in a m6A-dependent manner via modification of the m6A site A982 located in 3'UTR region (PubMed:35338654).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:55584"/>
            <dbReference type="Rhea" id="RHEA-COMP:12414"/>
            <dbReference type="Rhea" id="RHEA-COMP:12417"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.348"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2 3">
            <dbReference type="Rhea" id="RHEA:55585"/>
        </physiologicalReaction>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="2 3">Affects vegetative growth and conidial formation and results in increased sensitivity to various stresses (PubMed:35338654). Decreases pathogenicity and activates plant host immune responses (PubMed:30535195, PubMed:35338654).</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MT-A70-like family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.348" evidence="3"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714455.1">
        <property type="nucleotide sequence ID" value="XM_003714407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSY9"/>
    <dbReference type="SMR" id="G4MSY9"/>
    <dbReference type="STRING" id="242507.G4MSY9"/>
    <dbReference type="EnsemblFungi" id="MGG_01492T0">
        <property type="protein sequence ID" value="MGG_01492T0"/>
        <property type="gene ID" value="MGG_01492"/>
    </dbReference>
    <dbReference type="GeneID" id="2679801"/>
    <dbReference type="KEGG" id="mgr:MGG_01492"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01492"/>
    <dbReference type="eggNOG" id="KOG2356">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027091_4_0_1"/>
    <dbReference type="InParanoid" id="G4MSY9"/>
    <dbReference type="OMA" id="WWSWGDQ"/>
    <dbReference type="PHI-base" id="PHI:8648"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001734">
        <property type="term" value="F:mRNA m(6)A methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829:SF4">
        <property type="entry name" value="N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0072">Autophagy</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0749">Sporulation</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <feature type="chain" id="PRO_0000462149" description="N6-methyladenosine RNA methyltransferase MTA1">
        <location>
            <begin position="1"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="30535195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="35338654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="4">
        <source>
            <dbReference type="PubMed" id="30535195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="5">
        <source>
            <dbReference type="PubMed" id="35338654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="6"/>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA54648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="376" mass="41556" checksum="938E40305D014B27" modified="2011-12-14" version="1">MTAATLFESTDGTVVLLDLPRSIEDAQQHPAAVTLPEAPSLVTNSCRDGTSWTRRLISSPPPETPFVTPEPKNGPSPLPAAAQVAQLMIQASVTGALEELRTNYSGPYLLPRQLSPQRMIADGGKAVDDYKSPHACDLESCSTTAEDATKGRYYFPPESHHVLGTIQETKTLLLQSAPNFNVIVLDPPWPNRSAKRKKGGYKVATTTDDIRALLSDVPIPSLLARDGLVAIWVTNKPAFLDMLTSPRDGILSEWGLELVGEWSWLKITTSAEPILPIDSAHRKPWEPLLIAQRKGSKRVFPPFWRRRVIVSVPDTHSRKPNIRDLVNPMLPPRSRGLEIFARNLTAGWWAWGDDVLHFQERSNWVMAESKSPATGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTM9</accession>
    <name>G4MTM9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 15 MND2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715394.1">
        <property type="nucleotide sequence ID" value="XM_003715346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTM9"/>
    <dbReference type="STRING" id="242507.G4MTM9"/>
    <dbReference type="GeneID" id="2683171"/>
    <dbReference type="KEGG" id="mgr:MGG_07188"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07188"/>
    <dbReference type="eggNOG" id="ENOG502S7CI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045844_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTM9"/>
    <dbReference type="OMA" id="QEWEHTD"/>
    <dbReference type="OrthoDB" id="5320532at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008402">
        <property type="entry name" value="APC_su15/mnd2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05841">
        <property type="entry name" value="Apc15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="42099" checksum="B1D2F12618C09AB4" modified="2011-12-14" version="1">MFSMALPELMPHDSHALWYSSSRAPIPTSFLDPAQNPSGHLTNEGLQDGSPGLQTRRHGAAAVERSALARLRADEVLQERRRHNVGNFGATWLKPPGITKSLYQLREERREAEEHAEAMRREQLAQQLAEAEAEGEGLMEGGGDVMDEAEDGAEDAGEAPVERDLDDEIPDADEGFGYDGATTTSEEDDSEDSNDTEDDGPVPERVSIGGAAQRTPDAHAAAQQRRELRQVVATEDRFLGMMSRGQAANNQEDDMYPGADDEVDDEEAAEMLQEDDLIYASYNNGGLDDGLDMDMDGDLDDDIPEAESGGYEHTDSDASLTSSDEDEDGPVETSFAQGHPSASSQFRSVNLRGQGQYGNPRASLDLSSVLSRDGSSLPGSSSPQVRRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTQ9</accession>
    <name>G4MTQ9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cysteine desulfurase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713705.1">
        <property type="nucleotide sequence ID" value="XM_003713657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTQ9"/>
    <dbReference type="SMR" id="G4MTQ9"/>
    <dbReference type="STRING" id="242507.G4MTQ9"/>
    <dbReference type="GeneID" id="2678067"/>
    <dbReference type="KEGG" id="mgr:MGG_04744"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04744"/>
    <dbReference type="eggNOG" id="KOG1549">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_2_1"/>
    <dbReference type="InParanoid" id="G4MTQ9"/>
    <dbReference type="OMA" id="LVTWQQI"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
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    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
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    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
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    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
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    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
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    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
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    <dbReference type="PANTHER" id="PTHR43586">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586:SF21">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE (PLP)-DEPENDENT ASPARTATE AMINOTRANSFERASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="23"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="403" mass="44592" checksum="911B0EE9930DAD17" modified="2011-12-14" version="1">MSQSTLDIKQVRGSFPALSVDQVFFDNAGGSQTLDKVIDSIREYLSNTNVQLGASYSTGQKSTDLYDKGYEAAAKYINASVDNIVLGSSTTQLFRNLSQTLNFSHGDEIIVSKIDHEANIASWVDLAERQKLVLKWWLPSQASLDASSPKLEVADLKDLLSDKTRLVTLTHASNILGTIHDVKAVSDAVHAQKDEALVCVDGVAYAPHRPIDVKALGVDIYCFSWYKVYGPHISMLYASDRANSQMKSLGHYFNPSKTVEDKLGLAGSSYELVASIPEVVTYLDGKEAAIEKQETLLSETLLKYLRSRDDVTIWGEKSSDGQLRVPTISFTVKGWGSQELVETVEKGTNFGFRWGSFYSVRLVEEMLDLGHDGITRVSMVHYNTVDEVERLVEALDKTLASKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUV6</accession>
    <name>G4MUV6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA repair protein rhp42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_01699</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPC family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714693.1">
        <property type="nucleotide sequence ID" value="XM_003714645.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MUV6"/>
    <dbReference type="STRING" id="242507.G4MUV6"/>
    <dbReference type="GeneID" id="2679173"/>
    <dbReference type="KEGG" id="mgr:MGG_01699"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01699"/>
    <dbReference type="eggNOG" id="KOG2179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003639_0_2_1"/>
    <dbReference type="InParanoid" id="G4MUV6"/>
    <dbReference type="OMA" id="TWPGKTK"/>
    <dbReference type="OrthoDB" id="300780at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000111">
        <property type="term" value="C:nucleotide-excision repair factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071942">
        <property type="term" value="C:XPC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2460:FF:000001">
        <property type="entry name" value="DNA repair protein Rad4 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.110">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2460">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.260.10">
        <property type="entry name" value="Transglutaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018327">
        <property type="entry name" value="BHD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004583">
        <property type="entry name" value="DNA_repair_Rad4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018325">
        <property type="entry name" value="Rad4/PNGase_transGLS-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018326">
        <property type="entry name" value="Rad4_beta-hairpin_dom1"/>
    </dbReference>
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        <property type="entry name" value="Rad4_beta-hairpin_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042488">
        <property type="entry name" value="Rad4_BHD3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036985">
        <property type="entry name" value="Transglutaminase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135:SF2">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135">
        <property type="entry name" value="DNA REPAIR PROTEIN XP-C / RAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10403">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10404">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10405">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03835">
        <property type="entry name" value="Rad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01030">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01031">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01032">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="7">
        <location>
            <begin position="613"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="8">
        <location>
            <begin position="674"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="9">
        <location>
            <begin position="744"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="374"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="591"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="872"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="601"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="874"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="931"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="965"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1045" mass="116873" checksum="936B2621AF527AD6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVM7</accession>
    <name>G4MVM7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RelA/SpoT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713943.1">
        <property type="nucleotide sequence ID" value="XM_003713895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVM7"/>
    <dbReference type="STRING" id="242507.G4MVM7"/>
    <dbReference type="GeneID" id="2679900"/>
    <dbReference type="KEGG" id="mgr:MGG_08914"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08914"/>
    <dbReference type="eggNOG" id="ENOG502RW56">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_282997_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVM7"/>
    <dbReference type="OMA" id="WILRETT"/>
    <dbReference type="OrthoDB" id="5086500at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF5">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RelA/SpoT" evidence="2">
        <location>
            <begin position="78"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1102" mass="126041" checksum="82E1C66A7B863CC9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX75</accession>
    <name>G4MX75_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_08299</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715780.1">
        <property type="nucleotide sequence ID" value="XM_003715732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX75"/>
    <dbReference type="SMR" id="G4MX75"/>
    <dbReference type="STRING" id="242507.G4MX75"/>
    <dbReference type="GeneID" id="2678527"/>
    <dbReference type="KEGG" id="mgr:MGG_08299"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08299"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023525_0_0_1"/>
    <dbReference type="InParanoid" id="G4MX75"/>
    <dbReference type="OMA" id="RSYWAVH"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="104"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="425"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="582"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="608"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="632"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="652"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA55973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="849" mass="94943" checksum="F6A5C472E06E67DF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2026-01-28" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYB0</accession>
    <name>YCK1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine/threonine protein kinase YCK1</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Casein kinase I homolog 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">YCK1</name>
        <name type="ORF">MGG_08097</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2019" name="Virulence" volume="10" first="719" last="733">
            <title>The casein kinase MoYck1 regulates development, autophagy, and virulence in the rice blast fungus.</title>
            <authorList>
                <person name="Shi H.B."/>
                <person name="Chen N."/>
                <person name="Zhu X.M."/>
                <person name="Su Z.Z."/>
                <person name="Wang J.Y."/>
                <person name="Lu J.P."/>
                <person name="Liu X.H."/>
                <person name="Lin F.C."/>
            </authorList>
            <dbReference type="PubMed" id="31392921"/>
            <dbReference type="DOI" id="10.1080/21505594.2019.1649588"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Serine/threonine protein kinase that plays crucial roles in regulating development, autophagy and virulence (PubMed:31392921). Negatively regulates the autophagy activity, probably via the phosphorylkation of VPS41 (PubMed:31392921). Also regulates the response to ionic hyperosmotic and heavy metal cation stresses (PubMed:31392921).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="2">Causes pleiotropic defects in growth, conidiation, conidial germination, and appressorium formation and penetration, therefore resulting in reduced virulence in rice seedlings and barley leaves (PubMed:31392921). Triggers quick lipidation of ATG8 and degradation of the autophagic marker protein ATG8 under nitrogen starvation condition (PubMed:31392921).</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715052.1">
        <property type="nucleotide sequence ID" value="XM_003715004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYB0"/>
    <dbReference type="SMR" id="G4MYB0"/>
    <dbReference type="FunCoup" id="G4MYB0">
        <property type="interactions" value="608"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYB0"/>
    <dbReference type="EnsemblFungi" id="MGG_08097T0">
        <property type="protein sequence ID" value="MGG_08097T0"/>
        <property type="gene ID" value="MGG_08097"/>
    </dbReference>
    <dbReference type="GeneID" id="2678342"/>
    <dbReference type="KEGG" id="mgr:MGG_08097"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08097"/>
    <dbReference type="eggNOG" id="KOG1165">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019279_1_1_1"/>
    <dbReference type="InParanoid" id="G4MYB0"/>
    <dbReference type="OMA" id="GRGWDYK"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14127">
        <property type="entry name" value="STKc_CK1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000160">
        <property type="entry name" value="Casein kinase I 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <feature type="chain" id="PRO_0000463446" description="Serine/threonine protein kinase YCK1">
        <location>
            <begin position="1"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="19"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="31392921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="3">
        <source>
            <dbReference type="PubMed" id="31392921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <evidence type="ECO:0000305" key="5">
        <source>
            <dbReference type="PubMed" id="31392921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="446" mass="50301" checksum="1EBB3F42AED06ED6" modified="2011-12-14" version="1">MASSSSNVVGVHYRVGKKIGEGSFGVIFEGTNLLNNQQVAIKFEPRKSDAPQLRDEYRTYKILVGCPGIPNVYYFGQEGLHNILVIDLLGPSLEDLFDHCNRRFTIKTVVMVAKQMLSRVQTIHEKNLIYRDIKPDNFLIGRPGTKTANVIHVVDFGMAKQYRDPKSKQHIPYRERKSLSGTARYMSINTHLGREQSRRDDLEALGHVFMYFLRGGLPWQGLKAATNKQKYEKIGEKKQTTAIKELCEGFPIQFEKYLTYVRNLGFEDTPDYDYLRELFTQALKESGGVEDGEYDWMKVSKDKKNDWDRQAMHNPSQRPGASNMELHGASRGAHASDLRDPRARLTVDRLNAAQPPPPSPIKANQGKDRRNAPGAIMASRGTAGGLRDMATPTGSTQAQFQNSTQNLPQRPMHQQSNMTQPQLNNGRPAEPEPTGFQKFMKVLCCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ74</accession>
    <name>G4MZ74_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715155.1">
        <property type="nucleotide sequence ID" value="XM_003715107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ74"/>
    <dbReference type="GeneID" id="5050908"/>
    <dbReference type="KEGG" id="mgr:MGG_12307"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12307"/>
    <dbReference type="HOGENOM" id="CLU_2334002_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ74"/>
    <dbReference type="OrthoDB" id="674963at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="98" mass="10825" checksum="0405082791FFFE9C" modified="2011-12-14" version="1">MPSQTADYHSHLSYTNMSNSSESSSGSRNGTFPSMATTTSPPPVDVPSYSKMMLDHQKRQMERSTPESRRGSSDRHSHQNGVTSTYNPPSSNHASYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZC8</accession>
    <name>G4MZC8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Endo-1,4-beta-xylanase D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_11400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713490.1">
        <property type="nucleotide sequence ID" value="XM_003713442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZC8"/>
    <dbReference type="SMR" id="G4MZC8"/>
    <dbReference type="STRING" id="242507.G4MZC8"/>
    <dbReference type="CAZy" id="CBM66">
        <property type="family name" value="Carbohydrate-Binding Module Family 66"/>
    </dbReference>
    <dbReference type="CAZy" id="GH43">
        <property type="family name" value="Glycoside Hydrolase Family 43"/>
    </dbReference>
    <dbReference type="GeneID" id="2677883"/>
    <dbReference type="KEGG" id="mgr:MGG_11400"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11400"/>
    <dbReference type="eggNOG" id="ENOG502SHQG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029926_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZC8"/>
    <dbReference type="OMA" id="YDAQTFL"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18827">
        <property type="entry name" value="GH43_XlnD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="AL/BT2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052176">
        <property type="entry name" value="Glycosyl_Hydrlase_43_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772">
        <property type="entry name" value="ENDO-1,4-BETA-XYLANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43772:SF2">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="3keto-disac_hyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 6 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0858">Xylan degradation</keyword>
    <feature type="domain" description="3-keto-alpha-glucoside-1,2-lyase/3-keto-2-hydroxy-glucal hydratase" evidence="7">
        <location>
            <begin position="311"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="5">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA53683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="487" mass="53770" checksum="E60CC38201954B50" modified="2011-12-14" version="1">MLIVTAHHDYTTSEAGNPFVDGWYADPDCQFYRGEYWVYPTSSYPYEQQTYLDAFSSPDLVNWTKHPRILTNENVTWAHKAMWAPSPISRNGKYYLYFGANDIQTNDELGGIGVGVADRPGGPYVDALGRPLIDKFHNGAQPIDQNVFIDDDGQAYIYYGGWSHCNVAKLNEDMISLGTFDDGTTYKEITPDQYVEGALMMKRNGRYYFFWSEGGWTGPDYAVSYAIADSPLGPFNRIARILQQDPAVATGSGHNGVLKVPGTDIHYIVYHRHPLGDQDGNHRQLAYDRIYFNPDGTIQPITMLVKDNFADGNMIGWQTYGGNWSVHDGHLFSGDGGKGDKAALNVNFGDQVLNADITLISGEKDAGLIFRASQLGQGEDLYSGYYAGISASGYIVLGRAVVENGTGTWHELHRVKGVAIETSKRYHLRIRAVGNKIDVLLGDMGTPKITFEDGERIGQWDAPASGTVGVRVHTAVAQFDNISVAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZP6</accession>
    <name>G4MZP6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_07035</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the COPE family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715217.1">
        <property type="nucleotide sequence ID" value="XM_003715169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZP6"/>
    <dbReference type="SMR" id="G4MZP6"/>
    <dbReference type="STRING" id="242507.G4MZP6"/>
    <dbReference type="GeneID" id="2683049"/>
    <dbReference type="KEGG" id="mgr:MGG_07035"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07035"/>
    <dbReference type="eggNOG" id="KOG3081">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049363_1_0_1"/>
    <dbReference type="InParanoid" id="G4MZP6"/>
    <dbReference type="OMA" id="MIVLSQH"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016478">
        <property type="entry name" value="Coatomer_esu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA55410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="297" mass="31465" checksum="B6C1A368DE820212" modified="2011-12-14" version="1">MDPYSAEGELINIHNHFHQGQFQEVVDYDTSSLSPENALPARVLQLRSRIALGQAADVLAEVKGESDPELVVVGALAQQALGKADAAVAVVEKLAEASGDNPVVQVVGGTVLQAAGKSEEALALLSKQQGNLDAVALTVQIHLALNRNDLALKEVKAARSWAQDSLLVNLAESWVGLRKGGEAYQQAFYVFEELAQSASTASVRTLVAQAVAELHLGRTEEAQAALEQATQKDPNFAETVANLLVLKVITGASADEQTSLLKKTAPDHPLLVDLEEKSALFDKAATKYSAKVSTVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N060</accession>
    <name>G4N060_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cellobiose dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_11036</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712902.1">
        <property type="nucleotide sequence ID" value="XM_003712854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N060"/>
    <dbReference type="SMR" id="G4N060"/>
    <dbReference type="GeneID" id="2676232"/>
    <dbReference type="KEGG" id="mgr:MGG_11036"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11036"/>
    <dbReference type="eggNOG" id="KOG1238">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011025_0_0_1"/>
    <dbReference type="InParanoid" id="G4N060"/>
    <dbReference type="OMA" id="IGYLQCA"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1210:FF:000004">
        <property type="entry name" value="Cellobiose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.410.10">
        <property type="entry name" value="Cholesterol Oxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053208">
        <property type="entry name" value="GMC_Oxidoreductase_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190:SF2">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE (AFU_ORTHOLOGUE AFUA_2G17620)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47190">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465587" evidence="4">
        <location>
            <begin position="24"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="5">
        <location>
            <begin position="805"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA53095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="841" mass="89638" checksum="44DCBE71B1703058" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0B9</accession>
    <name>G4N0B9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HAUS augmin-like complex subunit 3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711264.1">
        <property type="nucleotide sequence ID" value="XM_003711216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0B9"/>
    <dbReference type="SMR" id="G4N0B9"/>
    <dbReference type="GeneID" id="2683307"/>
    <dbReference type="KEGG" id="mgr:MGG_07387"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07387"/>
    <dbReference type="eggNOG" id="ENOG502SQZ7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027731_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0B9"/>
    <dbReference type="OMA" id="KFMERWG"/>
    <dbReference type="OrthoDB" id="5314201at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="62069" checksum="CD500405D760298C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0E2</accession>
    <name>G4N0E2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_06197</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712083.1">
        <property type="nucleotide sequence ID" value="XM_003712035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0E2"/>
    <dbReference type="SMR" id="G4N0E2"/>
    <dbReference type="FunCoup" id="G4N0E2">
        <property type="interactions" value="984"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N0E2"/>
    <dbReference type="GeneID" id="2684363"/>
    <dbReference type="KEGG" id="mgr:MGG_06197"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06197"/>
    <dbReference type="eggNOG" id="KOG1562">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048199_1_0_1"/>
    <dbReference type="InParanoid" id="G4N0E2"/>
    <dbReference type="OMA" id="FLYHEMM"/>
    <dbReference type="OrthoDB" id="38125at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.140.10:FF:000001">
        <property type="entry name" value="SPE3p Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000013">
        <property type="entry name" value="Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030668">
        <property type="entry name" value="Spermi_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002010">
        <property type="entry name" value="PRK00811.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000502">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="12"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA52276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="293" mass="33383" checksum="F612377023E0F26E" modified="2011-12-14" version="1">MSGEITHETIKDGWFREISDMWPGQAMTLKVEKVLHHERSKYQDVLIFQSTDYGKVLVLDNVIQCTERDEFSYQEMITHLAMNSHPNPKKVLVIGGGDGGVLREVVKHDCVEEAILCDIDEAVIRLSKEYLPNMSAGFNHPKVKVHVGDGFKFLADYQNTFDVIITDSSDPEGPAESLFQKPYFQLLFNALTEGGVITTQAENQWLHLPLITKLRKDCKEIFPVAEYAYTTIPTYPSGQIGFMVCSKDPKANLKEPLRSWTQEEELEKCRYYSSDIHKASFVLPNFARKALQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0M3</accession>
    <name>G4N0M3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Biotrophy-associated secreted protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712961.1">
        <property type="nucleotide sequence ID" value="XM_003712913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0M3"/>
    <dbReference type="GeneID" id="2683676"/>
    <dbReference type="KEGG" id="mgr:MGG_07749"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07749"/>
    <dbReference type="eggNOG" id="ENOG502S1KA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_124589_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0M3"/>
    <dbReference type="OMA" id="SKCCANQ"/>
    <dbReference type="OrthoDB" id="2132010at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465794" description="Biotrophy-associated secreted protein 2" evidence="1">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="18472" checksum="B2C37B84E2DC0C4E" modified="2011-12-14" version="1">MVRLSTPALLAFVALAVATPQPITPDPSGAKNVGNGAGKQFITGACRSTADCAQPACCAGIAGDSSIGICSGLAVGNAAGKTGCGFGDGGARAAPAPAAAAPPPPPVAAPVAAPAAGNMSTGGAAAVVSGTCPVDSAKSGSQNVGKGNKSQFITGQCLSKADCASNCCVGQASGAGECRAELVATQAGLSCDFSCTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0X5</accession>
    <name>G4N0X5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptide hydrolase</fullName>
            <ecNumber evidence="14">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_13012</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="14"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712160.1">
        <property type="nucleotide sequence ID" value="XM_003712112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0X5"/>
    <dbReference type="SMR" id="G4N0X5"/>
    <dbReference type="GeneID" id="5048946"/>
    <dbReference type="KEGG" id="mgr:MGG_13012"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13012"/>
    <dbReference type="eggNOG" id="KOG2195">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025866_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0X5"/>
    <dbReference type="OMA" id="FTHSWNQ"/>
    <dbReference type="OrthoDB" id="2214at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005132177" description="Peptide hydrolase" evidence="14">
        <location>
            <begin position="20"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="169"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA52353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="371" mass="39643" checksum="6C5B12468D47C81A" modified="2011-12-14" version="1">MQITRSLVLLATSGMLASAAPTAKTPADDASTERHLVKVAPADPGTWLTDEEKDVLAVNRVGFHDITGVSEEELAVLSADPDEVKLEARQAVTYPTTLANQAEAVRLSNQATTTNPQSWLTTLSNFQTRHYRSSTGTQAGTWLQQQLRSIVGSKGTVSTITHSFNQPSIIVRIPGQTSNLVITGAHYDSTGGSTTARSPGAEDDGSGVVVIMEALRVLVASSFAPKNTLEFHFYGGEEGGLLGSRDVFANYRSNGRRVLAYLNQDMSGYSPGGKLTIYTDYVDTGLTAYVRRIAQASAGVAPSSSSCGYGCSDHASARSNGFPAAYVGDEPIGTSATWIHSSNDSIDRIQWPTILRHAKFVINYLVEASYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1D4</accession>
    <name>G4N1D4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09528</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712212.1">
        <property type="nucleotide sequence ID" value="XM_003712164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1D4"/>
    <dbReference type="STRING" id="242507.G4N1D4"/>
    <dbReference type="GeneID" id="2680483"/>
    <dbReference type="KEGG" id="mgr:MGG_09528"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09528"/>
    <dbReference type="eggNOG" id="KOG2651">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016581_1_0_1"/>
    <dbReference type="InParanoid" id="G4N1D4"/>
    <dbReference type="OMA" id="LQAPYNW"/>
    <dbReference type="OrthoDB" id="10258156at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052220">
        <property type="entry name" value="METTL25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12496">
        <property type="entry name" value="CGI-41 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12496:SF0">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="138"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="611" mass="68883" checksum="D7E721F69507790C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1Q3</accession>
    <name>G4N1Q3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">H/ACA ribonucleoprotein complex subunit CBF5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Centromere-binding factor 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">H/ACA ribonucleoprotein complex subunit cbf5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">H/ACA snoRNP protein CBF5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Small nucleolar RNP protein CBF5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_07518</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs and play a central role in ribosomal RNA processing. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. Catalyzes pseudouridylation at position 93 in U2 snRNA. Also catalyzes pseudouridylation of mRNAs; H/ACA-type snoRNAs probably guide pseudouridylation of mRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>uridine in 5S rRNA = pseudouridine in 5S rRNA</text>
            <dbReference type="Rhea" id="RHEA:47036"/>
            <dbReference type="Rhea" id="RHEA-COMP:11730"/>
            <dbReference type="Rhea" id="RHEA-COMP:11731"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine in snRNA = pseudouridine in snRNA</text>
            <dbReference type="Rhea" id="RHEA:51124"/>
            <dbReference type="Rhea" id="RHEA-COMP:12891"/>
            <dbReference type="Rhea" id="RHEA-COMP:12892"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711432.1">
        <property type="nucleotide sequence ID" value="XM_003711384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1Q3"/>
    <dbReference type="SMR" id="G4N1Q3"/>
    <dbReference type="FunCoup" id="G4N1Q3">
        <property type="interactions" value="1504"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N1Q3"/>
    <dbReference type="GeneID" id="2683438"/>
    <dbReference type="KEGG" id="mgr:MGG_07518"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07518"/>
    <dbReference type="eggNOG" id="KOG2529">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032087_3_2_1"/>
    <dbReference type="InParanoid" id="G4N1Q3"/>
    <dbReference type="OMA" id="KYGRTNE"/>
    <dbReference type="OrthoDB" id="10250002at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000495">
        <property type="term" value="P:box H/ACA sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02572">
        <property type="entry name" value="PseudoU_synth_hDyskerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21148">
        <property type="entry name" value="PUA_Cbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2350.10:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003280">
        <property type="entry name" value="PRK04270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dyskerin-like" evidence="14">
        <location>
            <begin position="33"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="13">
        <location>
            <begin position="283"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="382"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="406"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00072225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00077661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA51625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="485" mass="53892" checksum="2B4945B9E7BF1663" modified="2011-12-14" version="1">MGGNKDALALARRDEEVDEEFSIKPEQVTPALDTSSWPLLLKNYDKLHIRTGHFTPIPNGSTPLRRDIKSYISSGVINLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCVIRLHDKVPGGEPEFARALETLTGALFQRPPLISAVKRQLRIRTIHESKLIEFDNDRHLGVFWVSCEAGTYIRTLCVHLGLMLGVGAHMQELRRVRSGAMDETKDLHTLHDVLDAQWLMDNTRDESYLRKVIQPLETLLTTYKRLVVKDSAVNAVCYGAKLMLPGLLRYEADIELHEEVVLMTTKGEAIAIGIAQMSTVEISSCDHGVVAKVKRCIMERDLYPRRWGLGPVAGEKKKLKADGKLDKFGRPNEATPSRWTQNYKDYSAPAPDAAAPAADEAAAATESPAKALPAPEAEPEAEADDGKKRKSKHEGETAEEKAERKRRKKEKKEKRASKAAAEEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1Z6</accession>
    <name>G4N1Z6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713113.1">
        <property type="nucleotide sequence ID" value="XM_003713065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1Z6"/>
    <dbReference type="GeneID" id="12986054"/>
    <dbReference type="KEGG" id="mgr:MGG_16955"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16955"/>
    <dbReference type="HOGENOM" id="CLU_2498289_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1Z6"/>
    <dbReference type="OMA" id="FYHEDFQ"/>
    <dbReference type="OrthoDB" id="10416817at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="86" mass="9615" checksum="B589839EC44468E5" modified="2011-12-14" version="1">MEDKPKDVRPKVQVIIEQPNASGAQAQNSFYHEDFQLTNQDPEQGDKVGHTKMILQEQSSSDYSSGNYVLARGEAKCGITTCFQIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N253</accession>
    <name>G4N253_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711476.1">
        <property type="nucleotide sequence ID" value="XM_003711428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N253"/>
    <dbReference type="SMR" id="G4N253"/>
    <dbReference type="GeneID" id="2683480"/>
    <dbReference type="KEGG" id="mgr:MGG_07560"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07560"/>
    <dbReference type="eggNOG" id="ENOG502SM62">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_636268_0_0_1"/>
    <dbReference type="InParanoid" id="G4N253"/>
    <dbReference type="OMA" id="SENFWVF"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="2">
        <location>
            <begin position="28"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="395" mass="41328" checksum="5DAD606F6A36B7C5" modified="2011-12-14" version="1">MVAIAPAAAAASTLAIPVFYQPLIDQQVIANISWGTPAQTPIPTVVDTGSYGFWVDGPNATVNSGSPYLGVLGPCNQTAQPAFNWRESSSHTGPYDEGKATYAYGGGGKLINCPYAVNDTMNFDGGSPSIDNVQVAIADFTLIKARSTTCDGAHYDKSILGLAPIPAIAGGPELRPELLRQGRIGSSVFSMWFDAPPADLNAPQMGRLLLGGVPQDKHTGELVTVHNAGLDRQEKGYYYVAMPEVRAAPINGSGPAKAVPVEQPDKPAPDCLVDSGTWGLTLPTSSEAFLLATGLEEDKPFILPRYPSACADIPADAGIELVFPDRDGNKNATVKIPYRSMAEGAGQVPNTCRLNVQLSDVGCTFGGTFYASAFIAHNDDDGTLQIAQGAVAGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2I3</accession>
    <name>G4N2I3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711499.1">
        <property type="nucleotide sequence ID" value="XM_003711451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2I3"/>
    <dbReference type="GeneID" id="12987071"/>
    <dbReference type="KEGG" id="mgr:MGG_16661"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16661"/>
    <dbReference type="HOGENOM" id="CLU_1409036_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2I3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="193" mass="21211" checksum="9120E245603AC717" modified="2011-12-14" version="1">MTFEDSKAPFYLKYGGSFHITRLEASDSEPVEPGPRASRLQTGLPGQGQHTASRKNRKWWKAQVPTWQQEVHQAGGFRVSGLSFSLKRPSTCEGAQDCPEASFVSCVPRVSRPCTSWVCIFNLPSVPAARSEATAPIDTASSACFRLCSQVSHQLGECGMLFEVLIWVATRQSNLAKRTLPCHRGSQQGYPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2M0</accession>
    <name>G4N2M0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protoporphyrinogen oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_07615</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711536.1">
        <property type="nucleotide sequence ID" value="XM_003711488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2M0"/>
    <dbReference type="SMR" id="G4N2M0"/>
    <dbReference type="STRING" id="242507.G4N2M0"/>
    <dbReference type="GeneID" id="2683535"/>
    <dbReference type="KEGG" id="mgr:MGG_07615"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07615"/>
    <dbReference type="eggNOG" id="ENOG502S73B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1199623_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2M0"/>
    <dbReference type="OMA" id="IFWNIPF"/>
    <dbReference type="OrthoDB" id="194386at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035657">
        <property type="term" value="C:eRF1 methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052190">
        <property type="entry name" value="Euk-Arch_PrmC-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875:SF1">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase small" evidence="4">
        <location>
            <begin position="73"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA51729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="242" mass="26965" checksum="67285C3D09B1AE6F" modified="2011-12-14" version="1">MSSTTTITVVATDKQKSGASPRDVWEKQISVLLDQANKHNKPYKAQFGPHNITIHPTVYSPAYFPETWWYGTHLPAIVNKGSWLEIGVGSGLVSLCIASAGSKTVSGVDINPNAVEFTANNLQANGLKGNFTVSDIFEKVEGKFDFIFWNHPWQYDSTIPDQLKSEKTHDSEYKLLRRFVAEAKDYLTEKGVILLGTSAYANLDAIKTIAQSNGYNHKELLRGQEPIGNHVVEEYYVIELSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2N9</accession>
    <name>G4N2N9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61</fullName>
            <ecNumber evidence="2">2.1.1.220</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">tRNA(m1A58)-methyltransferase subunit TRM61</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_04871</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.1.1.220" evidence="2"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712352.1">
        <property type="nucleotide sequence ID" value="XM_003712304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2N9"/>
    <dbReference type="FunCoup" id="G4N2N9">
        <property type="interactions" value="622"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N2N9"/>
    <dbReference type="GeneID" id="2675317"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04871"/>
    <dbReference type="eggNOG" id="KOG2915">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="G4N2N9"/>
    <dbReference type="OrthoDB" id="1925287at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160107">
        <property type="term" value="F:tRNA (adenine(58)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049470">
        <property type="entry name" value="TRM61_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133:SF2">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08704">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 C-terminal" evidence="11">
        <location>
            <begin position="129"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 C-terminal" evidence="11">
        <location>
            <begin position="314"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="73"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="484"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="508"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="537"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="549"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA52545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="585" mass="64880" checksum="364EB1945EA25503" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3G2</accession>
    <name>G4N3G2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711647.1">
        <property type="nucleotide sequence ID" value="XM_003711599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3G2"/>
    <dbReference type="SMR" id="G4N3G2"/>
    <dbReference type="STRING" id="242507.G4N3G2"/>
    <dbReference type="GeneID" id="12984171"/>
    <dbReference type="KEGG" id="mgr:MGG_16696"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16696"/>
    <dbReference type="eggNOG" id="ENOG502RNT6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1170835_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3G2"/>
    <dbReference type="OMA" id="WEQNICR"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
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        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="58"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="237" mass="26906" checksum="333427702A61C044" modified="2011-12-14" version="1">MLLLNPTRSRTCTIVQNKHKPKHKFLPSETPGCIRQKHDRWPHAHHVLTRWPARPGFSPYDVLEQPRDGPYSKRRFYELVMVYHPDRWVHGTYHGIPKQTRVERYRLILAANAILSDPVRRRAYDEYGVGWAPGGTDLSRRSPGQPWKGGNGGNDGNSRNAKGQRDEQYPSGGDSCHWEGQPRGSQQRPIFMDNSSFAAMLLWLASSLSYLLWSVASCRAESNVAYPLFGTPPCSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3R7</accession>
    <name>G4N3R7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_16711</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711698.1">
        <property type="nucleotide sequence ID" value="XM_003711650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3R7"/>
    <dbReference type="SMR" id="G4N3R7"/>
    <dbReference type="FunCoup" id="G4N3R7">
        <property type="interactions" value="1227"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N3R7"/>
    <dbReference type="GeneID" id="12984189"/>
    <dbReference type="KEGG" id="mgr:MGG_16711"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16711"/>
    <dbReference type="eggNOG" id="KOG2171">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003794_1_1_1"/>
    <dbReference type="InParanoid" id="G4N3R7"/>
    <dbReference type="OMA" id="ANACGCV"/>
    <dbReference type="OrthoDB" id="7862313at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="8">
        <location>
            <begin position="387"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA51891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1102" mass="121392" checksum="ED8E17A0CD327C93" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3S9</accession>
    <name>G4N3S9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05006</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712509.1">
        <property type="nucleotide sequence ID" value="XM_003712461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3S9"/>
    <dbReference type="SMR" id="G4N3S9"/>
    <dbReference type="GeneID" id="2675288"/>
    <dbReference type="KEGG" id="mgr:MGG_05006"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05006"/>
    <dbReference type="eggNOG" id="ENOG502RZ7A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043194_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3S9"/>
    <dbReference type="OMA" id="MWEKTHQ"/>
    <dbReference type="OrthoDB" id="412109at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043124">
        <property type="term" value="P:negative regulation of canonical NF-kappaB signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="416" mass="47537" checksum="93645A94EEAE0971" modified="2011-12-14" version="1">MMNDPSERPSKRARILSSINPYQIDGPQPPQSASPASPKRTQPQKPQPSDRPSRDAEAEAGEQSSKSGMNDSYSSTRPSKFRFKDPARKKDRRDRESDHTSDRHHRSRRHRGDEDDERHRSRRHRHDHGEEAGEDERSSTSHRHRHRRRRRDKEEAPPDPEPEDPFAGPPLDPDAAFRESLFDAMADDEGAAYWEGVYGQPIHTLGGGAGELESMTEDEYAAHIRAKMWEKTHAGLLEARERKRRERAERDEERARDRRARDDAGRVDDAVEARLRRGRDRRLRREWRERWARYCDAWARWDKGLAEDEALGLLTGGGDAWPVESGRRADVNSAGVKAFFTQCLDAVAEEKAGGKAASSSSAGGDVAARLKEERVRWHPDKIQQRLGGRVDEDLGRDVTAVFQIVDNLWSEMRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N407</accession>
    <name>G4N407_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Deoxyribonuclease tatD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_05910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711736.1">
        <property type="nucleotide sequence ID" value="XM_003711688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N407"/>
    <dbReference type="SMR" id="G4N407"/>
    <dbReference type="STRING" id="242507.G4N407"/>
    <dbReference type="GeneID" id="2684065"/>
    <dbReference type="KEGG" id="mgr:MGG_05910"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05910"/>
    <dbReference type="eggNOG" id="KOG3020">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031506_1_0_1"/>
    <dbReference type="InParanoid" id="G4N407"/>
    <dbReference type="OMA" id="CCPREVQ"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA51929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="341" mass="37567" checksum="EB2BF7D639EA2686" modified="2011-12-14" version="1">MAQKFDFPAEAPLRPSRKLRFADVAVTATAKEFAGIYRGKQQHAPDVDAVLHRASSAGVAKVMLTGMSPSDVSFNLDVARRRPPGTTFVTIGIHPYHAAEPWADAAAASSGLYFDRLAATIREVQTGSPGVLAAFGELGLDYDRLDVCGRDEQLRTFRAQLDVVAREAFDLPLFLHCRAAFADFVDVLTPYLPRLPRRGLVHSFVGSREEMEVLTGRMGLDVSVNGFSFKDDECLDMVRHVPLERLQLETDAPWGEVLPTTNAVVARYLANVPPPEVQSKKRDKFEMGKMVKGRNESCCIDRVAYVVAGLKGIGVDEVAEAAWRNSVEMFRLERDVEEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N412</accession>
    <name>G4N412_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711741.1">
        <property type="nucleotide sequence ID" value="XM_003711693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N412"/>
    <dbReference type="GeneID" id="2684062"/>
    <dbReference type="KEGG" id="mgr:MGG_05913"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05913"/>
    <dbReference type="HOGENOM" id="CLU_1267119_0_0_1"/>
    <dbReference type="InParanoid" id="G4N412"/>
    <dbReference type="OMA" id="MKATSMI"/>
    <dbReference type="OrthoDB" id="5243083at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465761" evidence="3">
        <location>
            <begin position="18"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA51934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="218" mass="21001" checksum="FF2B0E554DFDA732" modified="2011-12-14" version="1">MKATSMILLSFGALAAAGSNVAGGYGNDDTVPAPAPAVSSPAPASAVKPVAGEPSGAAKKSDDEDCETKPVPAPMATPSAAAPPSAKKVPNSDVAPAAQSSSSTPTAKPAMEKTLVISVPSVTMPAALSKPSILNDITSLIADMKPTSMIKVPGAAKPTQSAYMAAPAPAPAAPAAPAPAYNATTPKPAPVTAGAVSVATGVGAATFVAAGFMAALLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4B2</accession>
    <name>G4N4B2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Young S.K."/>
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                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
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                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
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                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
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                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
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                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
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                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
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                <person name="Lee Y.H."/>
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    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
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                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Priest M."/>
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                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    <dbReference type="Proteomes" id="UP000009058">
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        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001164">
        <property type="term" value="F:RNA polymerase I core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048538">
        <property type="entry name" value="Rrn7_cyclin_C"/>
    </dbReference>
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        <property type="entry name" value="Rrn7_cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033599">
        <property type="entry name" value="TAF1B/Rrn7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021752">
        <property type="entry name" value="TF_Rrn7_Zf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31576">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31576:SF2">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20645">
        <property type="entry name" value="Rrn7_cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20644">
        <property type="entry name" value="Rrn7_cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11781">
        <property type="entry name" value="Zn_ribbon_RRN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRN7-type" evidence="11">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Rrn7/TAF1B N-terminal cyclin" evidence="12">
        <location>
            <begin position="87"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Rrn7/TAF1B C-terminal cyclin" evidence="13">
        <location>
            <begin position="258"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="129"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006899"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA52058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="549" mass="63024" checksum="BDBD8C5BC3C5169C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6J7</accession>
    <name>G4N6J7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716985.1">
        <property type="nucleotide sequence ID" value="XM_003716937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6J7"/>
    <dbReference type="SMR" id="G4N6J7"/>
    <dbReference type="GeneID" id="2684711"/>
    <dbReference type="KEGG" id="mgr:MGG_06556"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06556"/>
    <dbReference type="eggNOG" id="KOG1201">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_5_2_1"/>
    <dbReference type="InParanoid" id="G4N6J7"/>
    <dbReference type="OMA" id="LAGTECH"/>
    <dbReference type="OrthoDB" id="10253736at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05339">
        <property type="entry name" value="17beta-HSDXI-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322">
        <property type="entry name" value="PKSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24322:SF736">
        <property type="entry name" value="RETINOL DEHYDROGENASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="306" mass="32831" checksum="12CF378DD6E73DF2" modified="2011-12-14" version="1">MDLGGKLPAGSFLAGGLFLAWFLNRWLNDRALNNGNAPSSYDWAKEIIVVTGGSGGIGAETVKKLAGRGSQIVVLDVLPLSYSNVPNVHYYECDLTKYDELQEVGKRISKEIGDPTVVIANAGICRGKPILSASKRDIELTFGVNNIALLFTAKTFLPSMVAKNHGHFLIIASQTGYIATPGLTDYSASKAATIAIYEGLHAEVGLMYGAPSVRVSCVSPTLVDTKMFQGMDSSAAPGGALRPEDLGARIAGIIHSGRAQHACVPHWSVSPLSFIRTWPDWLRVWCMASSVGLYDNLRPHDPMASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6K8</accession>
    <name>G4N6K8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716996.1">
        <property type="nucleotide sequence ID" value="XM_003716948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6K8"/>
    <dbReference type="SMR" id="G4N6K8"/>
    <dbReference type="GeneID" id="2684701"/>
    <dbReference type="KEGG" id="mgr:MGG_06546"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06546"/>
    <dbReference type="eggNOG" id="ENOG502RM8I">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_503501_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6K8"/>
    <dbReference type="OMA" id="FEDIYCH"/>
    <dbReference type="OrthoDB" id="5233232at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="541" mass="59519" checksum="930C1532319D777C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N717</accession>
    <name>G4N717_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03640</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EHA49930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716249.1">
        <property type="nucleotide sequence ID" value="XM_003716201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N717"/>
    <dbReference type="SMR" id="G4N717"/>
    <dbReference type="GeneID" id="2676516"/>
    <dbReference type="KEGG" id="mgr:MGG_03640"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03640"/>
    <dbReference type="eggNOG" id="KOG0254">
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    <dbReference type="HOGENOM" id="CLU_000960_22_0_1"/>
    <dbReference type="InParanoid" id="G4N717"/>
    <dbReference type="OMA" id="NLFHDPR"/>
    <dbReference type="OrthoDB" id="2351791at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF59">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="580"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="666"/>
            <end position="686"/>
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    </feature>
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        <location>
            <begin position="204"/>
            <end position="696"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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    </feature>
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        <location>
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            <end position="47"/>
        </location>
    </feature>
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        <location>
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    </feature>
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        <location>
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    </feature>
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        <location>
            <begin position="119"/>
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        </location>
    </feature>
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        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA49930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="727" mass="78859" checksum="EBBA879063E301C2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7I4</accession>
    <name>G4N7I4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003717112.1"/>
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    <dbReference type="FunCoup" id="G4N7I4">
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    <dbReference type="GeneID" id="2684564"/>
    <dbReference type="KEGG" id="mgr:MGG_06409"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06409"/>
    <dbReference type="eggNOG" id="ENOG502S178">
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    <dbReference type="HOGENOM" id="CLU_067862_1_1_1"/>
    <dbReference type="InParanoid" id="G4N7I4"/>
    <dbReference type="OMA" id="CNFCGIR"/>
    <dbReference type="OrthoDB" id="2103474at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
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    <dbReference type="InterPro" id="IPR025187">
        <property type="entry name" value="DUF4112"/>
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    <dbReference type="PANTHER" id="PTHR35519">
        <property type="entry name" value="MEMBRANE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519:SF2">
        <property type="entry name" value="PH DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13430">
        <property type="entry name" value="DUF4112"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="25817" checksum="B20779A8E66A3F1D" modified="2011-12-14" version="1">MASFLFKLAAKRALQDKMKMNTNSQDPFYEYEEIEVHKGGKTEIIYKKKGKKPIPKGLSKNDAQVLKGVRSRAYHLDMSLFSFCGIRFGWSSVIGLVPAIGDALDALMALILVKKCMKVDDGLPLTILSRMVFNILVDFVIGLVPFVGDLADAAYRANIRNAWLLELYLVNKYDEMNKRGISDPADLENQPSSSAATASVAPPKPAKKKFFGRGGETDDTSTPAEGHTRRDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7W4</accession>
    <name>G4N7W4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proline--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_06345</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717237.1">
        <property type="nucleotide sequence ID" value="XM_003717189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7W4"/>
    <dbReference type="SMR" id="G4N7W4"/>
    <dbReference type="FunCoup" id="G4N7W4">
        <property type="interactions" value="410"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7W4"/>
    <dbReference type="GeneID" id="2684500"/>
    <dbReference type="KEGG" id="mgr:MGG_06345"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06345"/>
    <dbReference type="eggNOG" id="KOG2324">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016739_2_2_1"/>
    <dbReference type="InParanoid" id="G4N7W4"/>
    <dbReference type="OMA" id="NCDYAAN"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050062">
        <property type="entry name" value="Pro-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753:SF2">
        <property type="entry name" value="PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="75"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA50918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="658" mass="73192" checksum="FC34D6E686ABE332" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N827</accession>
    <name>G4N827_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metal homeostatis protein BSD2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_03477</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716448.1">
        <property type="nucleotide sequence ID" value="XM_003716400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N827"/>
    <dbReference type="FunCoup" id="G4N827">
        <property type="interactions" value="34"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N827"/>
    <dbReference type="GeneID" id="2676826"/>
    <dbReference type="KEGG" id="mgr:MGG_03477"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03477"/>
    <dbReference type="eggNOG" id="KOG4812">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041193_0_0_1"/>
    <dbReference type="InParanoid" id="G4N827"/>
    <dbReference type="OMA" id="SFVWNGM"/>
    <dbReference type="OrthoDB" id="10003116at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031398">
        <property type="term" value="P:positive regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22212">
        <property type="entry name" value="NDFIP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019325">
        <property type="entry name" value="NEDD4/Bsd2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396:SF5">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN 1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10176">
        <property type="entry name" value="NEDD4_Bsd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="80"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="362" mass="38092" checksum="CEF1CF14CA15511C" modified="2011-12-14" version="1">MAGGYERVNAHDEEDHNSPIQPGRIPNSPPPSFRSRESSIFGRDRNDARQKDVDTTLADAFDSADDSDDDVDDTQRLVRATPGTSQASTSAAPSSSSSQVGVSSTATRNAAAPGGQSATAQPPAPASGAAATPFRVYGAGMQSDGVFSNLSAKPERGEEKEEQPPTYEQAAADAAPPYWETTIMAPGFGGADEVYIDGMPVGSFFSFVWNGMITITFQPLIGFLLTYLLHSTHAAKNGSRGGLGITLIQYGFQFKATTGAGAGSMHTSGSSEPENYAEPPDPNAHDFDPNAVQQGGAGTGGSDISGSDWLAYVLMIVGWFILIRSLSDYIRARRHEQLVLQSPDRGLGVAIVAEGETPDRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N864</accession>
    <name>G4N864_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA polymerase epsilon subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_06302</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717284.1">
        <property type="nucleotide sequence ID" value="XM_003717236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N864"/>
    <dbReference type="STRING" id="242507.G4N864"/>
    <dbReference type="GeneID" id="2684457"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06302"/>
    <dbReference type="InParanoid" id="G4N864"/>
    <dbReference type="OrthoDB" id="653904at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017054">
        <property type="term" value="C:negative cofactor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001046">
        <property type="term" value="F:core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22906">
        <property type="entry name" value="HFD_DRAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF5">
        <property type="entry name" value="DR1-ASSOCIATED COREPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="4">
        <location>
            <begin position="271"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="195"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="351"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
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        <location>
            <begin position="351"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="379"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA50965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="390" mass="43135" checksum="0E7DD618A44E39C9" modified="2011-12-14" version="1">MSYAPASPDLSSFYSGSADSHNAGHHHHHHHSSSSGFGFPVQVSSSNPRSRPLSPPHGLTLPGGPTSSVTTNYQANRVGEVHFSLHSNQQHHHHLHTPYHEHPYSLHTPISPQPNPSQAVHAQNHLHYIHSPFQTQKNIQSLQIVPPSNHNINTSQPGPSPIGLQYIPPYSAQQYKSEPDDAFCFSSVQEIPQRDLFPQQPHRRSYSQPHSDATRIKPEVKSEEQYGVHSPQNIRIKSETQPSYPLPEAMPPRRSAAAAQPSVIASPVKTRFPTARIKRIMQADEEVGKVAQQTPIAVGKALEMFMVALVSKSHDVAKDKGAKRVTAQHLKQVIESDDQWDFLREIVGRISETEEKAGRAGGRAKAESSSDEEVPEPKKKGRGGRKKKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8U6</accession>
    <name>G4N8U6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_03385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716559.1">
        <property type="nucleotide sequence ID" value="XM_003716511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8U6"/>
    <dbReference type="SMR" id="G4N8U6"/>
    <dbReference type="GeneID" id="2676986"/>
    <dbReference type="KEGG" id="mgr:MGG_03385"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03385"/>
    <dbReference type="HOGENOM" id="CLU_752414_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8U6"/>
    <dbReference type="OMA" id="ESSYWKL"/>
    <dbReference type="OrthoDB" id="5224171at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="40174" checksum="7478F78D34B54B47" modified="2011-12-14" version="1">MSTPSNQNEYWVIFYQDARRWMHMFHSSLRSGKSFQAQVVVRYVGGSQLTGEPCVRKRPEEKHDQDGRRALRDEAANLASLEQDLKEKGLSLGAAHIAELLRKTSNDDPDSVESSYWKLYNLGSLHGLLLKLRDNNASRSILPAMAARVARHMLIAIKSSLVTPKGGLLHNDIVSSNVFVHFPPGGDDKLPDFYLGDWGDSQPENRPRQRFNGVQESLKRLDGILNEITQLHAADPTVHHQLSTVLGSVCTGAPANDPELATFLAERLNKAVETAARLEKDALDTVAGSIGSVKAVLQSFVIVPRPARYRTAEEAEAAVEANHLRGCTLQLVENGKIDFTKGMVPGGSDSSSASESSLADLVGDFAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9J7</accession>
    <name>G4N9J7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">xanthine dehydrogenase</fullName>
            <ecNumber evidence="4">1.17.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">MGG_12738</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>hypoxanthine + NAD(+) + H2O = xanthine + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24670"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>xanthine + NAD(+) + H2O = urate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="20">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="20">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="20">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="20">Binds 2 [2Fe-2S] clusters.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.4" evidence="4"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716708.1">
        <property type="nucleotide sequence ID" value="XM_003716660.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N9J7"/>
    <dbReference type="STRING" id="242507.G4N9J7"/>
    <dbReference type="GeneID" id="5050113"/>
    <dbReference type="KEGG" id="mgr:MGG_12738"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12738"/>
    <dbReference type="eggNOG" id="KOG0430">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001681_1_2_1"/>
    <dbReference type="InParanoid" id="G4N9J7"/>
    <dbReference type="OMA" id="PHPTQER"/>
    <dbReference type="OrthoDB" id="8300278at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004854">
        <property type="term" value="F:xanthine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000015">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000003">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.50:FF:000001">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000002">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014307">
        <property type="entry name" value="Xanthine_DH_ssu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02963">
        <property type="entry name" value="xanthine_xdhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 20" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9 19" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 20" id="KW-0408">Iron</keyword>
    <keyword evidence="12 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 20" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="13" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="21">
        <location>
            <begin position="25"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="22">
        <location>
            <begin position="262"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="1304"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="135"/>
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            <name>FAD</name>
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            <name>Mo</name>
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    </evidence>
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            <dbReference type="PROSITE" id="PS51387"/>
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            <dbReference type="EMBL" id="EHA50389.1"/>
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    <sequence length="1382" mass="151593" checksum="F7B93C8BC18892C5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9V2</accession>
    <name>G4N9V2_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S8</fullName>
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        <name evidence="6" type="ORF">MGG_03251</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Ribosomal_S8e_like"/>
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    </dbReference>
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        <property type="entry name" value="40S ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="1"/>
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    </feature>
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        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA50404.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="202" mass="22815" checksum="F1867280864187D2" modified="2011-12-14" version="1">MGISRDSRHKRSATGAKRAHYRQKRAWEAGRQPASTKIGAKRIHTVRVRGGNTKYRALRLDSGNFSWGSEGVTRKTRVIAVAYHPSNNELVRTNTLTKSAVIQIDAAPFRQWYEAHYGQSLGRRRQAKQAKEGEEVKKSKSVEKKQAERFAARGKVDSALEKQFEAGRVFAVVSSRPGQSGRCDGYILEGEELAFYQRKLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAY9</accession>
    <name>G4NAY9_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">DUF1776 family protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00679</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA48751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003718287.1"/>
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    <dbReference type="STRING" id="242507.G4NAY9"/>
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    <dbReference type="KEGG" id="mgr:MGG_00679"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00679"/>
    <dbReference type="eggNOG" id="ENOG502QWSS">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OrthoDB" id="5308060at2759"/>
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        <property type="component" value="Chromosome 5"/>
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        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="DUF1776_fun"/>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
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    <dbReference type="PANTHER" id="PTHR43313:SF1">
        <property type="entry name" value="3BETA-HYDROXYSTEROID DEHYDROGENASE DHS-16"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08643">
        <property type="entry name" value="DUF1776"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA48751.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="56246" checksum="F8EB3F93E1047C7C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB39</accession>
    <name>G4NB39_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718385.1">
        <property type="nucleotide sequence ID" value="XM_003718337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB39"/>
    <dbReference type="GeneID" id="5050689"/>
    <dbReference type="KEGG" id="mgr:MGG_11533"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11533"/>
    <dbReference type="eggNOG" id="ENOG502SXGS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_687115_0_0_1"/>
    <dbReference type="InParanoid" id="G4NB39"/>
    <dbReference type="OMA" id="LCEFWIN"/>
    <dbReference type="OrthoDB" id="67027at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNase_III_dom"/>
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        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNASE_3_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="2">
        <location>
            <begin position="161"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="401" mass="44904" checksum="574510726FE841EC" modified="2011-12-14" version="1">MLSRWADLVLRHSAEPRRRTLENQWKKPWLHDIRRREREAKKDSMYGLPTGLESAPPFSFRPSGGPRSALPPRYRVREEPTCTSRPSFELFSKDLESAPRSSFRVPGRLLSAPLPFSIHSPSNHLPLKPSIAELHHRESDISPLRYPTHELKRPYNVLGKVALLEKIINYHFDAAHVLLAIEALETTTIPYRYTNSKREMRTNQVLAIYGDVVSAAQLCEFWINNRPAHGLVPGNWSTLQMQLLGNQNLARVGKNAGLGTCMINGPIGNKEVVSKKTKMIRMATTVEAILGAVHKAGGPRALRAVMERLGLLSHHLLGTRNGDDEEPVDEIGMRCVSGGKPTPKMDPNRLPSKLKTTIEVMPPTNDPRTPSISHPKSDCEGAALLQRRLAREEIEKQVSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBA9</accession>
    <name>G4NBA9_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718455.1">
        <property type="nucleotide sequence ID" value="XM_003718407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBA9"/>
    <dbReference type="SMR" id="G4NBA9"/>
    <dbReference type="STRING" id="242507.G4NBA9"/>
    <dbReference type="GeneID" id="2675161"/>
    <dbReference type="KEGG" id="mgr:MGG_00587"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00587"/>
    <dbReference type="eggNOG" id="ENOG502SQYS">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059772_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBA9"/>
    <dbReference type="OMA" id="FMTQPAY"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052635">
        <property type="entry name" value="Sec_Metab_Biosynth_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39607:SF1">
        <property type="entry name" value="B-ZIP TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39607">
        <property type="entry name" value="XANTHOCILLIN BIOSYNTHESIS CLUSTER TRANSCRIPTION FACTOR XANC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="333" mass="36713" checksum="B7F0700F15F3DAD9" modified="2011-12-14" version="1">MISHHLYPAVPTTFDPHESYYDASRMSHHYYSAEDNSAKLPPPVNMFAMPQHHHYAAYAPAPAPRQYSGTSSAFSASANPDEDWTKISDLAERRRIQNRIAQRNYRKKLKRRLEDLERRAGSSDGASTDGNEKTTTTTTSKASTASSSTKSGSKARSPKKATKQQSSPPPAALSPPKTYPEQFTPPMNPDDELLFAQPYASEPRDRSHSPPSLFYTYPPPEDMMLPYGATTSPPYTAGEYLVPTTVPVTLPSMTHFSDAIKREPSYGEEMSPYMGNYGYMPGIEVSQAAPYDNSNPHTPPLSHGFDHSTSCSDSGYEYPTTPLSMPASPGMIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBK7</accession>
    <name>G4NBK7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_10759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717696.1">
        <property type="nucleotide sequence ID" value="XM_003717648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBK7"/>
    <dbReference type="GeneID" id="2676294"/>
    <dbReference type="KEGG" id="mgr:MGG_10759"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10759"/>
    <dbReference type="HOGENOM" id="CLU_1796852_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBK7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="144" mass="16307" checksum="1432FE2C3CADDBD0" modified="2011-12-14" version="1">MATKDRWRASLQKLSSKISGEKRLWGPKIGELKEFVFFSADSKKDNGRPLSDVAPGAFVNDLSDQRRKARTPRPRTLQPYDFRGHNILLLSDSDSERDDFPEEFTATATGPERQRYSVLGDGDKEHEGDGKPKKTQAEVKVQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC80</accession>
    <name>G4NC80_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vesicular-fusion protein SEC17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_01121</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SNAP family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717813.1">
        <property type="nucleotide sequence ID" value="XM_003717765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC80"/>
    <dbReference type="SMR" id="G4NC80"/>
    <dbReference type="FunCoup" id="G4NC80">
        <property type="interactions" value="905"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NC80"/>
    <dbReference type="GeneID" id="2674779"/>
    <dbReference type="KEGG" id="mgr:MGG_01121"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01121"/>
    <dbReference type="eggNOG" id="KOG1586">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046329_1_0_1"/>
    <dbReference type="InParanoid" id="G4NC80"/>
    <dbReference type="OMA" id="WSVKEYL"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15832">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000049">
        <property type="entry name" value="Alpha-soluble NSF attachment protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF8">
        <property type="entry name" value="ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00448">
        <property type="entry name" value="NSFATTACHMNT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="292" mass="32808" checksum="C5FFC6A2F6FE7EF4" modified="2011-12-14" version="1">MAEDPRALLQKADKALASASGGFSFFGGKEEKLQTAADYYIQAANAFKMQKSEREAGQTFEKAAQIQNGKLNEPDDAANTYVDAFKAYRKSSPEDAARCVEMAIAQYCRKGNFRRAATFKENVGEMFEVEVGDLKKAMEAYEAAAGWYEGDGAAVLSNKLWLKVADIAALDADYYKAIEAYEKVSQASINNNLMKYSVKDYFLKGGLCHLATKDMVSARRALEKYTEMDPTFPSTREYKLLADICESVEGNDREKFEDDLVAFDRMTKLDKWKTTILLRIKEQIEEADNEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDV3</accession>
    <name>G4NDV3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">nitric oxide dioxygenase</fullName>
            <ecNumber evidence="4">1.14.12.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_00198</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 nitric oxide + NADH + 2 O2 = 2 nitrate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2 nitric oxide + NADPH + 2 O2 = 2 nitrate + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="4"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718919.1">
        <property type="nucleotide sequence ID" value="XM_003718871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDV3"/>
    <dbReference type="SMR" id="G4NDV3"/>
    <dbReference type="FunCoup" id="G4NDV3">
        <property type="interactions" value="322"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NDV3"/>
    <dbReference type="GeneID" id="2674580"/>
    <dbReference type="KEGG" id="mgr:MGG_00198"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00198"/>
    <dbReference type="eggNOG" id="KOG3378">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_12_0_1"/>
    <dbReference type="InParanoid" id="G4NDV3"/>
    <dbReference type="OMA" id="ADIHYEV"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase NAD(P)H activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071500">
        <property type="term" value="P:cellular response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046210">
        <property type="term" value="P:nitric oxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08922">
        <property type="entry name" value="FHb-globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06184">
        <property type="entry name" value="flavohem_like_fad_nad_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.490.10:FF:000003">
        <property type="entry name" value="Flavohemoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000034">
        <property type="entry name" value="Flavohemoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="FLAVOHEMOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0216">Detoxification</keyword>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Globin" evidence="17">
        <location>
            <begin position="26"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="18">
        <location>
            <begin position="173"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA49335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="447" mass="48654" checksum="7AC57445FABA4B1B" modified="2011-12-14" version="1">MSAVRDKQQPDAAPAAAAAGNKPAPSITPEQVAVVKSTAPVLKEHGVTITTVFYKNMIDAHPELHNVFSTTSQATGAQPRALASAVLAYATHIDDLARLSHAVSRIAHKHVSLHITPDQYDIVGKYLIEAIGQVLGDAATPEIVAAWIAAYGVLADVFIGVEGKMYQEHSDWLGFRKFRVLRKEAEAESITSFYLAPSDGKTPLPRFLPGQYVSVQLFVPELGYLQSRQYSLSEGYRKGGEHYRISVKREEGVEVGAPGIISNMLHDKISVGDEVEVSHPQGEFFVDPADATKAGAPLVLLSAGVGATPLLSILESVTVADGGVPAPAATRPVSWIHASRSRAQRPFETRVAEIQKTVGEERLRSRLFLGKIDAEKDVANQHFHFGGGRMDLDKLDADRDLHTSDARAEYYLCGPEAWMLDTREKLEQMGVAHERIHLELFATGDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE38</accession>
    <name>G4NE38_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_00826</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718157.1">
        <property type="nucleotide sequence ID" value="XM_003718109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE38"/>
    <dbReference type="GeneID" id="2674189"/>
    <dbReference type="KEGG" id="mgr:MGG_00826"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00826"/>
    <dbReference type="eggNOG" id="ENOG502SHVM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_3_7_1"/>
    <dbReference type="InParanoid" id="G4NE38"/>
    <dbReference type="OrthoDB" id="5429740at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF155">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="33"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA48573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="352" mass="38960" checksum="F4E1CFEB04DCA40C" modified="2011-12-14" version="1">MEVQSATATDDRGPRITAVMLTLTSISSVFVSLRLYTRAVIKKGLWAEDYIMALALVTSWGEAGLNVVAVRHGLGRHMWDLTREQRRGAQLWSILGSVTGVFGLGLPKIAMAAMLNRVLLAGYWSSMASWFLSIMSMVNFTVASMLILFQCATPQKAVWARDPDNECYSIRLVIGILFSAFGDLYFAVWPALVVSKLYISRPKALGLSCALGLGIMWVKHVLKTEPQRVKTKAFAGTNANKCLRRRWIQNDAVATFGRPGYSFAESAALLTCSSIPFLAPICRVFARWFSRTKARAGDGDVDSVPDLVQSLGRDQRLHHRALDTESGLAALRSTPRHRHRSMLRPLTPSRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE75</accession>
    <name>G4NE75_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BEM46 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718988.1">
        <property type="nucleotide sequence ID" value="XM_003718940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE75"/>
    <dbReference type="SMR" id="G4NE75"/>
    <dbReference type="FunCoup" id="G4NE75">
        <property type="interactions" value="637"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NE75"/>
    <dbReference type="ESTHER" id="mago7-g4ne75">
        <property type="family name" value="ABHD13-BEM46"/>
    </dbReference>
    <dbReference type="MEROPS" id="S09.A35"/>
    <dbReference type="GeneID" id="2675206"/>
    <dbReference type="KEGG" id="mgr:MGG_00142"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00142"/>
    <dbReference type="eggNOG" id="KOG4391">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029375_2_0_1"/>
    <dbReference type="InParanoid" id="G4NE75"/>
    <dbReference type="OMA" id="QYWTSED"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="107"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="321" mass="35250" checksum="8E912673B50697EA" modified="2011-12-14" version="1">MTSSSSSPPPTSFLEQTVSVISSVAGYMRLPAMASTGVAAVLTSLLYFKQKSLIYSSNMPPNSRTQVSRPSQFNIKDFEELMIPTPDGEKLSAFYIRGSRNGRNSNVTIIMFHGNAGNIGHRLPIARHLVELMGCNVFMLEYRGYGLSTGTADESGLMIDAQTGLDYLRDRPETRKHRLVVYGQSLGGSVAIRLVSKNQAAGDIVGLILENTFLSMRKLIPSVIPPTKYFAFLCHQVWPSDVAIPNITKVPILFLSGQQDEIVPPSHMRQLYELSAAPNKIWKPLPNGDHNSSVLEDGYFDAISDFVASVASEPPRLSEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEY9</accession>
    <name>G4NEY9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRAL/TRIO domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718299.1">
        <property type="nucleotide sequence ID" value="XM_003718251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEY9"/>
    <dbReference type="SMR" id="G4NEY9"/>
    <dbReference type="FunCoup" id="G4NEY9">
        <property type="interactions" value="142"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NEY9"/>
    <dbReference type="GeneID" id="2675121"/>
    <dbReference type="KEGG" id="mgr:MGG_00707"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00707"/>
    <dbReference type="eggNOG" id="KOG1470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014001_1_2_1"/>
    <dbReference type="InParanoid" id="G4NEY9"/>
    <dbReference type="OMA" id="DIHARPC"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.525.10:FF:000013">
        <property type="entry name" value="Phosphatidylinositol transfer protein PDR16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="119"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="403" mass="44889" checksum="84B27C6F02C50144" modified="2011-12-14" version="1">MTTATSNGSAQDKAAVGILKTPISAPLEGCTPPAKDPLTKEQEIKYDWLLEQVKKWTEVPSTKGKGGPLTDAERMWLTRECLLRYLRATKWVEKDAEKRLRETLTWRRDFDVADLTWDHISPEQETGKQVILGFDKEGRVCHYLCPGRQNTQPSHRQVEHLVFMLERVLDLLPAQREKLVLLINFKQGKNRSYTAPGIGQAREVLNILQTHYPERLGRALIVNVPWVVQGFFKLITPFIDPLTRDKLKFNEDMSNYVPKEQLWTEISGGALEFEYDHSTYWPALRKMCEERQVEKEKRWTAGGKQIGELEDYLGGKASQGITPPVAATTEVAATATATSTAPVAAPAATAAASEVAPIAVAQESAAPEKPAVEGAKKEESGAVSEKQGDKVEDLKVDELKVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF74</accession>
    <name>G4NF74_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rRNA-processing protein FYV7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719636.1">
        <property type="nucleotide sequence ID" value="XM_003719588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF74"/>
    <dbReference type="STRING" id="242507.G4NF74"/>
    <dbReference type="GeneID" id="2677696"/>
    <dbReference type="KEGG" id="mgr:MGG_04187"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04187"/>
    <dbReference type="eggNOG" id="ENOG502SBYU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076390_0_0_1"/>
    <dbReference type="InParanoid" id="G4NF74"/>
    <dbReference type="OMA" id="HPTRELM"/>
    <dbReference type="OrthoDB" id="2135053at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41805">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41805:SF1">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN FYV7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="26801" checksum="83D9253F153B1E54" modified="2011-12-14" version="1">MPPSNKRSRDGAKSGPYTAQQPAAKRARLGLPVDPANLPDGPWKRKLTKVKKELFHQKKVEKQYAKVKARYQRQKEEQKKVAAGDEIYVHPDRQVHAAATVGEQGTSSEDGTVQATEELPAAAAAATSPPPPDATAEDPVVHKGKPRAAPTDSRQRRGKPAYFQKELAEAEEHKRAAAEREAQAKAREEERARKTAERDRLRKAMAKARKPSGMPGRHGGRVKLGRESGILLDKVKKMVGHNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFG5</accession>
    <name>G4NFG5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_04251</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719560.1">
        <property type="nucleotide sequence ID" value="XM_003719512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFG5"/>
    <dbReference type="SMR" id="G4NFG5"/>
    <dbReference type="STRING" id="242507.G4NFG5"/>
    <dbReference type="GeneID" id="2677170"/>
    <dbReference type="KEGG" id="mgr:MGG_04251"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04251"/>
    <dbReference type="eggNOG" id="KOG2493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015355_3_0_1"/>
    <dbReference type="InParanoid" id="G4NFG5"/>
    <dbReference type="OMA" id="AWKTGNA"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF57">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="497"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="539"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="583"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="616" mass="66006" checksum="31727A00E0BF9E10" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFJ8</accession>
    <name>G4NFJ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719172.1">
        <property type="nucleotide sequence ID" value="XM_003719124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFJ8"/>
    <dbReference type="GeneID" id="2678965"/>
    <dbReference type="KEGG" id="mgr:MGG_08799"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08799"/>
    <dbReference type="HOGENOM" id="CLU_2097341_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFJ8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466227" evidence="2">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="116" mass="12479" checksum="202B37E94F55DDF0" modified="2011-12-14" version="1">MKLSVFFTALLASSTVALSVPLFQRSTPPPTVQPATSRPEVDPNFGRPTDPFGKPTHEKRDTNDDDDDDEPVARKRSSAMFPGSRRARKRDAGLISGLPFGPIGSDKVDDAPAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFZ8</accession>
    <name>G4NFZ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719322.1">
        <property type="nucleotide sequence ID" value="XM_003719274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFZ8"/>
    <dbReference type="GeneID" id="12985766"/>
    <dbReference type="KEGG" id="mgr:MGG_17591"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17591"/>
    <dbReference type="HOGENOM" id="CLU_2996932_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFZ8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="57" mass="6213" checksum="ED1DA82087FB556B" modified="2011-12-14" version="1">MYYLGQKGLKAADRTGANLHTKRGGEHTVYTCSKGYSYKTTNGEFAIAHQAACDGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGB6</accession>
    <name>G4NGB6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cellulase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_10423</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719440.1">
        <property type="nucleotide sequence ID" value="XM_003719392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGB6"/>
    <dbReference type="SMR" id="G4NGB6"/>
    <dbReference type="STRING" id="242507.G4NGB6"/>
    <dbReference type="GeneID" id="2682035"/>
    <dbReference type="KEGG" id="mgr:MGG_10423"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10423"/>
    <dbReference type="eggNOG" id="ENOG502QUKB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039562_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGB6"/>
    <dbReference type="OMA" id="YATEMVD"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31263:SF0">
        <property type="entry name" value="CELLULASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14560)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466267" evidence="6">
        <location>
            <begin position="20"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="7">
        <location>
            <begin position="37"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="471" mass="51773" checksum="9737E2404C429C16" modified="2011-12-14" version="1">MRGLGTLSALVAPVAAALADGPFTTSGRWILAGDNKTNVNLAGINWPGAGEAMIPEGLQYQSAAAIAARIQSLGMNVVRLTYATEMVDQIFANGGADIPVQKSLIAALGQQNGTAVWEMVKRSNPQFNDNITRLQAFDTVAAELSKQDIYVLVDNHVSKAQWCCSPLDGNSWWGDTYFSTANWTRGLTYMTEHTRDWPNLIGLSLRNELRQPLTNITLYQQAYNWETWYARTREGAAAIHKANPKALVFLSGLDSDTTLQPVVEGSNLTPGKGMFRPGDYFEGAENKLVLELHSYANIINEGLAKNCTGLKETLVQGGWSGLSTAAPGGTKVKNRMPTLMTEFGWGQNDQEWNSNYSTCIQDFLRDDVRAGWMIWAISGSYYIRECKQDYDEPWGILNHDWSDWRSEKHAMGELKRLVNSTLSTTMDGAGEGGGKDSPSPSPDKKNASESIRGSLYNFLWGVAALAIFNMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGD6</accession>
    <name>G4NGD6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719460.1">
        <property type="nucleotide sequence ID" value="XM_003719412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGD6"/>
    <dbReference type="GeneID" id="12985918"/>
    <dbReference type="KEGG" id="mgr:MGG_17630"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17630"/>
    <dbReference type="HOGENOM" id="CLU_3032858_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGD6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="55" mass="5697" checksum="6759AA6EC388339A" modified="2011-12-14" version="1">MPSPPRLVTLLAYLRFPGLPGLVQNGPFSPTSTTLAKASWGSNSPGNLRMTALGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGQ5</accession>
    <name>G4NGQ5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">lytic cellulose monooxygenase (C4-dehydrogenating)</fullName>
            <ecNumber evidence="15">1.14.99.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_04057</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[(1-&gt;4)-beta-D-glucosyl]n+m + reduced acceptor + O2 = 4-dehydro-beta-D-glucosyl-[(1-&gt;4)-beta-D-glucosyl]n-1 + [(1-&gt;4)-beta-D-glucosyl]m + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the polysaccharide monooxygenase AA9 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.56" evidence="15"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719782.1">
        <property type="nucleotide sequence ID" value="XM_003719734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGQ5"/>
    <dbReference type="SMR" id="G4NGQ5"/>
    <dbReference type="STRING" id="242507.G4NGQ5"/>
    <dbReference type="GeneID" id="2677670"/>
    <dbReference type="KEGG" id="mgr:MGG_04057"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04057"/>
    <dbReference type="eggNOG" id="ENOG502SING">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031730_4_0_1"/>
    <dbReference type="InParanoid" id="G4NGQ5"/>
    <dbReference type="OMA" id="PKDTPNG"/>
    <dbReference type="OrthoDB" id="3496539at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030248">
        <property type="term" value="F:cellulose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21175">
        <property type="entry name" value="LPMO_AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049892">
        <property type="entry name" value="AA9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005103">
        <property type="entry name" value="AA9_LPMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000254">
        <property type="entry name" value="CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035971">
        <property type="entry name" value="CBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353:SF2">
        <property type="entry name" value="ENDO-BETA-1,4-GLUCANASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33353">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03443">
        <property type="entry name" value="AA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00734">
        <property type="entry name" value="CBM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00236">
        <property type="entry name" value="fCBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57180">
        <property type="entry name" value="Cellulose-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00562">
        <property type="entry name" value="CBM1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51164">
        <property type="entry name" value="CBM1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466615" description="lytic cellulose monooxygenase (C4-dehydrogenating)" evidence="16">
        <location>
            <begin position="20"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="CBM1" evidence="17">
        <location>
            <begin position="257"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA47415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="315" mass="34251" checksum="1549D985386BC459" modified="2011-12-14" version="1">MKLGFATVAVAILASGANAHYWFDKLIINGRETSAYQYVRQSSRPTLYNPIKWIDTRDNSTPDMDDMRCNQGAFNSAGRTQTAEVAAGTRVGFRLAAGGTMFHPGPGLAYMSRAPGTASTYRGDGDWFKIYETGVCRQGADFSRDAWCTYEKPTMEFNIPKDTPNGEYLLRVEHIGVHRSHVNQPEFYVSCAQIKVVNGGSGRPGPTIKFPGGYSRNHPAFENYSVYNGYRSFPMPGPAVWSGGGGGGSTPAPPSGGCAALYEQCGGSGFNGPKCCSSGSCKVSNEWYSQCFIGRSFMYKGFEFDSRHSLVTVHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH20</accession>
    <name>G4NH20_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719897.1">
        <property type="nucleotide sequence ID" value="XM_003719849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH20"/>
    <dbReference type="SMR" id="G4NH20"/>
    <dbReference type="GeneID" id="2677329"/>
    <dbReference type="KEGG" id="mgr:MGG_03967"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03967"/>
    <dbReference type="eggNOG" id="KOG4177">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_572379_0_0_1"/>
    <dbReference type="InParanoid" id="G4NH20"/>
    <dbReference type="OrthoDB" id="4772757at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="360"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="506" mass="56467" checksum="FB515A349E93213C" modified="2011-12-14" version="1">MFKLLDLPPELVHEILVAVAKSRSISRALHIRLVSRFFASAMTDALFASGQLGLDGPDSGLFGTQIDEAPRLELWSRYMIYLGLSRNRPGLWKLQTLHRVAKAIVHHPKSRFAQARLGGESMERESQVRDYFTQLCRLPSTIRQRGLLSSHKNTNGWNKARDLASPRPHFCSSLIAGAAHLDEFDVVLDLVESFDCDDCDLNEATATAISDAASAGNLRMVLFLLSSKDGPERYPRGIELAIIGAAWGNQPEIIEWALSQLPQPVSPSEERDHFNRMHRILLDAMSLTTCLECFRRCYEYQPIVHGSFGCCHALSRGDNIMAKAAGRGDLDMCVYMMASCRRSPNGLVKGEKDPQIFQKYFRSPLRHAARAGRSDVVEFLLYSGADPVQPSRFFISGDLLSSEEPQSVFNAAIQGGSVRCLELIVEAYNKKTSQLKPGLLAHFWTGELSTGFMLAVRRENEDMILFLLQMCHDLDLKSWEVAGDALTEAHNLGLESMIELLQSPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH97</accession>
    <name>G4NH97_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GTP-binding protein rho4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_03901</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719974.1">
        <property type="nucleotide sequence ID" value="XM_003719926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH97"/>
    <dbReference type="SMR" id="G4NH97"/>
    <dbReference type="STRING" id="242507.G4NH97"/>
    <dbReference type="GeneID" id="2677195"/>
    <dbReference type="KEGG" id="mgr:MGG_03901"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03901"/>
    <dbReference type="eggNOG" id="KOG0393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_21_1_1"/>
    <dbReference type="InParanoid" id="G4NH97"/>
    <dbReference type="OMA" id="RTKRTCI"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04132">
        <property type="entry name" value="Rho4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000678">
        <property type="entry name" value="Rho GTPase Rho4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="257"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA47607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="292" mass="32300" checksum="4861684A567A17FC" modified="2011-12-14" version="1">MASQYQYRNSQYNSNQVSNEKYEPSMQRRSTIERREPRGTRSSDGTVSTMMSASTGRESSATAMTEAPAYSKKIVVVGDGGCGKTCLLISYSQGYFPEKYVPTVFENYITYPTHGSSGKTVELALWDTAGQEEYDRLRPLSYPETDLIFVCFAIDCPNSLENVMDKWYPEVLHFCPYTPLILVGLKSDLRFKKTCIDMLKTQGLTPVTTEQGQAVARKMNAQYMECSSKEMRGVDEIFERALDTVIANDRKTLEAQAAASGGGGGSYSSHGGHGIPGVGGMPKKRKTRCNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHA2</accession>
    <name>G4NHA2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Lariat debranching enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_03897</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lariat debranching enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719979.1">
        <property type="nucleotide sequence ID" value="XM_003719931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHA2"/>
    <dbReference type="SMR" id="G4NHA2"/>
    <dbReference type="STRING" id="242507.G4NHA2"/>
    <dbReference type="GeneID" id="2677191"/>
    <dbReference type="KEGG" id="mgr:MGG_03897"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03897"/>
    <dbReference type="eggNOG" id="KOG2863">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005893_3_0_1"/>
    <dbReference type="InParanoid" id="G4NHA2"/>
    <dbReference type="OMA" id="GIDDPLC"/>
    <dbReference type="OrthoDB" id="407609at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008419">
        <property type="term" value="F:RNA lariat debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00844">
        <property type="entry name" value="MPP_Dbr1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007708">
        <property type="entry name" value="DBR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041816">
        <property type="entry name" value="Dbr1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849:SF0">
        <property type="entry name" value="LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849">
        <property type="entry name" value="RNA LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05011">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01124">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lariat debranching enzyme C-terminal" evidence="14">
        <location>
            <begin position="428"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="290"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="403"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="585"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="343"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="377"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="600"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="637"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA47612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="649" mass="69766" checksum="81F7A5D49373F0AE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHB5</accession>
    <name>G4NHB5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Defect at low temperature protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLT1</name>
        <name evidence="9" type="ORF">MGG_03887</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Required for growth under high-pressure and low-temperature conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DLT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719992.1">
        <property type="nucleotide sequence ID" value="XM_003719944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHB5"/>
    <dbReference type="STRING" id="242507.G4NHB5"/>
    <dbReference type="GeneID" id="2677474"/>
    <dbReference type="KEGG" id="mgr:MGG_03887"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03887"/>
    <dbReference type="eggNOG" id="ENOG502RAJJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022833_2_0_1"/>
    <dbReference type="InParanoid" id="G4NHB5"/>
    <dbReference type="OMA" id="SHYEYAR"/>
    <dbReference type="OrthoDB" id="4096362at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038869">
        <property type="entry name" value="DLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021:SF1">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="337"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="457"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="428"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="493" mass="53299" checksum="2CADA80F13180760" modified="2011-12-14" version="1">MLSATRVFRIVYKTFYLLLYILLLILLLGSPADIIYQSLWVPPKHEYFVIVLSAAYFVTIFIVSFVYSMRLWINRGVLAAIPRSRIPIDKGDVPSSIRKEIVSGLSRSASIAFDARPRVLPPSLSAPFGAHVGQYGRGQNESSTGVASDGGRSGTPQEKQKKRFKFPTLKKTSTVGTEVGVNFPPPKPVWGEIEHNGWGSPLSPDFPTLEYATVISELANLIEAKAVTLAPEVPLSATAYESSMGPDGQQLGHAHGLGMRDPGAVALLQRGSLGMRDYLASLAELGVLPPSQTAAQFLVAYEHARFSTRPLSARRFREVMQLFAELLRSMVPIDPMSLSSPSMSMRTDSSETTGSSGSESSKASQIRHRHRRRRQMRHPHAVSAGARASSWQYKTAPTTPKDLRMAPGKSPSARTMATAAALEAAFSSLPSSSSSSPRLAASPDRLFRSNSRNSIASFAQSRHPYPNSQASSGSLRSLASAGSVVVRIGVTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHE2</accession>
    <name>G4NHE2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17739</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720019.1">
        <property type="nucleotide sequence ID" value="XM_003719971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHE2"/>
    <dbReference type="SMR" id="G4NHE2"/>
    <dbReference type="GeneID" id="12987127"/>
    <dbReference type="KEGG" id="mgr:MGG_17739"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17739"/>
    <dbReference type="HOGENOM" id="CLU_2996935_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHE2"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="57" mass="6415" checksum="9E0AFADE19426C34" modified="2011-12-14" version="1">MSWRLAPSQPYSLGRCCVSFCLFFELDAWLEQIVSMVVKLGKQATFIPMGQSGTKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHN8</accession>
    <name>G4NHN8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hydroxyquinol 1,2-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03773</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720115.1">
        <property type="nucleotide sequence ID" value="XM_003720067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHN8"/>
    <dbReference type="SMR" id="G4NHN8"/>
    <dbReference type="STRING" id="242507.G4NHN8"/>
    <dbReference type="GeneID" id="2677415"/>
    <dbReference type="KEGG" id="mgr:MGG_03773"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03773"/>
    <dbReference type="eggNOG" id="ENOG502QU2V">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046727_1_1_1"/>
    <dbReference type="InParanoid" id="G4NHN8"/>
    <dbReference type="OMA" id="AMGPKTT"/>
    <dbReference type="OrthoDB" id="5238185at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03461">
        <property type="entry name" value="1_2-HQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039390">
        <property type="entry name" value="1_2-HQD/HQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF7">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catechol dioxygenase N-terminal" evidence="8">
        <location>
            <begin position="32"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="7">
        <location>
            <begin position="115"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="297" mass="32981" checksum="764001BBC67C2E49" modified="2011-12-14" version="1">MASTQKPNGNAKPQYDPDFTDNVIKAIGPKTNPRIAEVMTSFIRHIHDFAREVDLTVDEWMMGVDMINRCGQMSNDRRNEGQLMCDVLGLESLVDEITSKKLVGAGYEATKSAILGPFFRKDTPPSANDTSIVKTMPSDGEVTFMHGVVTDAATGKPIKGVTVDIWQCSTNGLYEQQDPDQADFNLRGKFTTDENGYYGLYCLRPVPYPVPYDGPAGEVLQLLDRHPYRPAHIHIIAGNEEYSPLTTQIFDKSSKYLVDDSVFAVKDDLVVDFKPVEGNPKATLELVYDIRLAAIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIA5</accession>
    <name>G4NIA5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720332.1">
        <property type="nucleotide sequence ID" value="XM_003720284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIA5"/>
    <dbReference type="GeneID" id="12987295"/>
    <dbReference type="KEGG" id="mgr:MGG_14927"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14927"/>
    <dbReference type="HOGENOM" id="CLU_2134021_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIA5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="113" mass="11314" checksum="36FF96AB4D4D0281" modified="2011-12-14" version="1">MASEPIETVTVTTTIRSLGEPTNSPEPPTLSPVPSLTPTTLATSVRQTSSTADPTALPADTDGQGSPTSGPPMGAIAGIITVRAESGSGWLNPQSEKGAGDRIPRACSLGASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJA3</accession>
    <name>G4NJA3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_17988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721062.1">
        <property type="nucleotide sequence ID" value="XM_003721014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJA3"/>
    <dbReference type="GeneID" id="12984877"/>
    <dbReference type="KEGG" id="mgr:MGG_17988"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17988"/>
    <dbReference type="eggNOG" id="ENOG502QY0U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1015689_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJA3"/>
    <dbReference type="OMA" id="DIAVPRM"/>
    <dbReference type="OrthoDB" id="5599902at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="51"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="166"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="246" mass="27945" checksum="A3BF3714CE1B8EA9" modified="2011-12-14" version="1">MPSIHDTLHHGSGHHSSGSGAITARRHSRADAEEPDDLFPDIPEAKKRKFILVEDSDRQSRLRVRVTLDGVDTREIPDSFRKNSSVYPRSYFPREMQSPPPSATGSKFFQDDLSDDPGAEDDGTTDTEGRRAARGARAKAMVRVPMVDGSEGEVAIPRMRRGFRGKEVRLNDLGYRMAWLQSRVFAGRTIFLQRALDCYRNKTRSAIESLMQDVKTVSPHLETRVGKRKWNERMRRSEKKDDTESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJI2</accession>
    <name>G4NJI2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721141.1">
        <property type="nucleotide sequence ID" value="XM_003721093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJI2"/>
    <dbReference type="GeneID" id="2682862"/>
    <dbReference type="KEGG" id="mgr:MGG_02646"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02646"/>
    <dbReference type="HOGENOM" id="CLU_046577_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJI2"/>
    <dbReference type="OMA" id="IYCNMET"/>
    <dbReference type="OrthoDB" id="5365129at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="339" mass="37774" checksum="A01316503D0EEE39" modified="2011-12-14" version="1">MSESIGAVLGVASAVAPFIDPTGISILIFSIVTLMLSLAEHPHQPDSHRQTAFRIHLGLDSCPGQNLGGDIPDVRVWDERGNFLGRFLGDDEDVPAGDFFDFTIDLEKPHQPTYALFSANENDVCIAYITQTLATGERYYSGVVFDGYDDLACTWISLHHIDDKSVSGIQLHIHEFKYTESNNKSIDYFCAGNPTMKFYTESDPTEIDRWETRRPEDLNSTRGIVHVPGQPQDDRRRSVRPSDRSCPRSLHASRLIKSRRGQSASMLCADPASRGPDFVSYSEGLYCNMETREVLPLCDGAAGRVTGCFDDGGNIVKRSEVERGDVLDELGYDRVDEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NK63</accession>
    <name>G4NK63_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Medium-chain specific acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_15041</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721291.1">
        <property type="nucleotide sequence ID" value="XM_003721243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NK63"/>
    <dbReference type="SMR" id="G4NK63"/>
    <dbReference type="STRING" id="242507.G4NK63"/>
    <dbReference type="GeneID" id="12985856"/>
    <dbReference type="KEGG" id="mgr:MGG_15041"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15041"/>
    <dbReference type="eggNOG" id="KOG0140">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_4_1_1"/>
    <dbReference type="InParanoid" id="G4NK63"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00567">
        <property type="entry name" value="ACAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF28">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="7">
        <location>
            <begin position="229"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA46548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="383" mass="41487" checksum="A0D70BE74A1812C3" modified="2011-12-14" version="1">MATWPRKPTLQRVAPEVPKARARVRRQAPAPARAGVGGGRRGAPGGPREVRGLGAGVSGRAARVPAARPADSGGDPDQQLDAFHELILMDEMARLPSGVAIALAGASNKRRWLPGLFSWQTSFCLAITEPTAGSDVGAIRTSAVLSADGSEYVVNGLKKWVTGAPWATHMTTAVRTSSSSSSSSGNKTSRPPSRSDISLLVIPLDSRGVSIRKIHNTGHNAGGSSWVELREERFILTVDCNRQARECLAEALRHAHERETFGRPLASHQIIRAKLAALARDVEAHWAWLEQLAHHVKRRGWQARDLAGPVALAKIQGGRVVERAVRESQQVHGGMAYERGKTITEQISRDLRLKVIGGGSEEILTDLAWREEHKVAKEREAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="74" xmlns="https://uniprot.org/uniprot">
    <accession>G5EGY2</accession>
    <name>G5EGY2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGCH7_ch7g684</name>
        <name evidence="9" type="ORF">MGG_02921</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15</strain>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">70-15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720798.1">
        <property type="nucleotide sequence ID" value="XM_003720750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EGY2"/>
    <dbReference type="SMR" id="G5EGY2"/>
    <dbReference type="FunCoup" id="G5EGY2">
        <property type="interactions" value="487"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EGY2"/>
    <dbReference type="GeneID" id="2682474"/>
    <dbReference type="KEGG" id="mgr:MGG_02921"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02921"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_0_1"/>
    <dbReference type="OMA" id="MVNQIFL"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102098">
        <property type="term" value="F:D-galacturonate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019698">
        <property type="term" value="P:D-galacturonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19121">
        <property type="entry name" value="AKR_AKR3D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000007">
        <property type="entry name" value="NAD(P)H-dependent D-xylose reductase xyl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044495">
        <property type="entry name" value="AKR3D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EAQ71277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA46055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="312" mass="34368" checksum="10FE14BC676B5C55" modified="2011-12-14" version="1">MADKDFTLNTGAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISSGIVKREDLFVVSKCWATYTTRCELGLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVPAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPLGSTGGPLLTAEPVVKIAEKHSISPAAVLLGYQIARGITVIPKSVNPDRIKANAQLKDLDAEDMKLLNDYSEQLAKDGKLNRYVFPPFGTDFGFPDKVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHG7</accession>
    <name>G5EHG7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g1117</name>
        <name evidence="3" type="ORF">MGG_15442</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720479.1">
        <property type="nucleotide sequence ID" value="XM_003720431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHG7"/>
    <dbReference type="GeneID" id="12987372"/>
    <dbReference type="KEGG" id="mgr:MGG_15442"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15442"/>
    <dbReference type="HOGENOM" id="CLU_1065868_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="261" mass="28268" checksum="6A55BEA25098F93A" modified="2011-12-14" version="1">MSPGSTSYPTDVGGRYNGGPTSNDQYGAPAGGFTSQMPPGNGPAGSTSYPADVGGRYNGGPTSNKPYDPYQAELDPKDPPKSVLKREQRKSDLLLLWLVSKVPLWHYMRLWQHINSVVKGEGTGKSKKSRRDKRGNKMLAWVAASFWEKAEDFGDNARNICACGLAVTMAVPLAIAGNCFARCGFEPGSPRNMLGRCVEKGAKACWGIYNREREYTARKQAKKLGQDQTGEQRENRPQGGQAGGSRVPHHAPDNGPTRGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHQ7</accession>
    <name>G5EHQ7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGCH7_ch7g401</name>
        <name evidence="11" type="ORF">MGG_02668</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15</strain>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721106.1">
        <property type="nucleotide sequence ID" value="XM_003721058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHQ7"/>
    <dbReference type="SMR" id="G5EHQ7"/>
    <dbReference type="FunCoup" id="G5EHQ7">
        <property type="interactions" value="273"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EHQ7"/>
    <dbReference type="GeneID" id="2682799"/>
    <dbReference type="KEGG" id="mgr:MGG_02668"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02668"/>
    <dbReference type="eggNOG" id="KOG1589">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099502_0_1_1"/>
    <dbReference type="OMA" id="FRQNFYQ"/>
    <dbReference type="OrthoDB" id="869189at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EAQ70994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA46363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="173" mass="19240" checksum="9F1631AD91986AFC" modified="2011-12-14" version="1">MSAAAATFVRSTARPVFRSGQIAAQARAAFRQQQWKQHAGRRWQSSAAPEAEANPSFFKRLWDSPIGIKTVHFWAPVMKWAVVLAGVSDFFRPAEKLSLTQNAALTATGFIWTRWCLIITPKNYLLAAVNFFLGIVGTIQVSRILMYQASQKDAVLPAIEEKVEEVKDAVKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHY4</accession>
    <name>G5EHY4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGCH7_ch7g1096</name>
        <name evidence="4" type="ORF">MGG_10319</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15</strain>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720503.1">
        <property type="nucleotide sequence ID" value="XM_003720455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHY4"/>
    <dbReference type="SMR" id="G5EHY4"/>
    <dbReference type="FunCoup" id="G5EHY4">
        <property type="interactions" value="35"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EHY4"/>
    <dbReference type="GeneID" id="2681894"/>
    <dbReference type="KEGG" id="mgr:MGG_10319"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10319"/>
    <dbReference type="eggNOG" id="ENOG502S4PT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078856_0_0_1"/>
    <dbReference type="OMA" id="HPTIIMT"/>
    <dbReference type="OrthoDB" id="5300823at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052841">
        <property type="entry name" value="PMP_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28040">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE YLR456W HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28040:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE YLR456W HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="2">
        <location>
            <begin position="24"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EAQ71689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA45760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="228" mass="24587" checksum="C91EECAE66F18C7F" modified="2011-12-14" version="1">MDHIPLNHEASAGDTHKTTTPDLPPEVIQCLENARFLHLATCTDNIPHVSLMSYTYLPSSPYSTSPVVVMTTNAASKKTNNLIINPNVSLLVHDWVSHRPPSSNRRPSGGSPGPEHRSSLASLLLNLNTSSISSISATINGSARLADAGSEEESFFKQQHLDNNTFEDSSAGASIFNSTPADGARPTFVEGEDVRVVVVKIQDVRISDWKGSVRDYVIVPSEPMVNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI56</accession>
    <name>G5EI56_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Ankyrin repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGCH7_ch7g858</name>
        <name evidence="15" type="ORF">MGG_03061</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15</strain>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">70-15</strain>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The VLRF1 domain mediates binding to the 60S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ANKZF1/VMS1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720619.1">
        <property type="nucleotide sequence ID" value="XM_003720571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI56"/>
    <dbReference type="FunCoup" id="G5EI56">
        <property type="interactions" value="182"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EI56"/>
    <dbReference type="GeneID" id="2682614"/>
    <dbReference type="KEGG" id="mgr:MGG_03061"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03061"/>
    <dbReference type="eggNOG" id="KOG2505">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014293_1_1_1"/>
    <dbReference type="OMA" id="GPHIFMC"/>
    <dbReference type="OrthoDB" id="429841at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047139">
        <property type="entry name" value="ANKZ1/VMS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041175">
        <property type="entry name" value="VLRF1/Vms1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036">
        <property type="entry name" value="ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036:SF2">
        <property type="entry name" value="TRNA ENDONUCLEASE ANKZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18826">
        <property type="entry name" value="bVLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52044">
        <property type="entry name" value="VLRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VLRF1" evidence="13">
        <location>
            <begin position="243"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="482"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="117"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="560"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="561"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="617"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EAQ71451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA45876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="656" mass="72829" checksum="EE08A17F9BE26644" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4G8</accession>
    <name>A0A151V4G8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-ketoglutarate-dependent taurine dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_12505</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845969.1">
        <property type="nucleotide sequence ID" value="XM_016990537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4G8"/>
    <dbReference type="SMR" id="A0A151V4G8"/>
    <dbReference type="FunCoup" id="A0A151V4G8">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="GeneID" id="5050385"/>
    <dbReference type="KEGG" id="mgr:MGG_12505"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12505"/>
    <dbReference type="eggNOG" id="ENOG502QS4K">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4G8"/>
    <dbReference type="OMA" id="ARGHPEN"/>
    <dbReference type="OrthoDB" id="10257314at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000005">
        <property type="entry name" value="TfdA family taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF10">
        <property type="entry name" value="TAUD_TFDA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="45"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KYQ30465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="371" mass="41704" checksum="BC2831C899229442" modified="2016-06-08" version="1">MSPSAVDVVTEVHNVAKKAIETESQTKYPEPLKLSGALDSYEYFDTTPIIGREYPNANLVDILNSPNSDELIRDLAITISQRGVVFFRAQDNLTNDLQKKLILRLGELTGRPKTSGLHIHPLLNAERETYGGDDNEISTISSAQNDKLYKKTWTQPDELSPKKQSTAQWHSDIAFEPVPADYTSLRLTELPKTGGDTLWASGYEIYDKISAPYQKFLETLSVTFAQKRFNEIADANGFSLYSQPRGAPENVGTDLRAVHPLVRTNPVTGWKSIFPVGGHVQHVNGLTDEESDGLLKWYLDLVYRNHELQTRLKWRNKNDIAIWDNRSVFHTATFDLEGQGDRFGNRAVGLGERPYLDPGSRSRREALAEGK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2022-10-12" modified="2025-04-09" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4J3</accession>
    <accession>Q2KEQ8</accession>
    <name>AA13_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AA13 family lytic polysaccharide monooxygenase A</fullName>
            <shortName evidence="8">LPMO13A</shortName>
            <ecNumber evidence="7">1.14.99.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LPMO13A</name>
        <name type="ORF">MGG_10208</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2016" name="FEBS Lett." volume="590" first="2737" last="2747">
            <title>Fungal lytic polysaccharide monooxygenases bind starch and beta-cyclodextrin similarly to amylolytic hydrolases.</title>
            <authorList>
                <person name="Nekiunaite L."/>
                <person name="Isaksen T."/>
                <person name="Vaaje-Kolstad G."/>
                <person name="Abou Hachem M."/>
            </authorList>
            <dbReference type="PubMed" id="27397613"/>
            <dbReference type="DOI" id="10.1002/1873-3468.12293"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>ACTIVITY REGULATION</scope>
        <scope>GLYCOSYLATION</scope>
        <scope>SUBCELLULAR LOCATION</scope>
    </reference>
    <comment type="function">
        <text evidence="7 9">Starch-active lytic polysaccharide monooxygenase that oxidizes the C1 position of starch substrates (PubMed:27397613). Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>starch + reduced acceptor + O2 = D-glucono-1,5-lactone-terminated malto-oligosaccharides + short-chain malto-oligosaccharides + acceptor + H2O.</text>
            <dbReference type="EC" id="1.14.99.55"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
        <text evidence="2">Binds 1 copper ion per subunit.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Activity is inhibited by both beta-cyclodextrin or amylose that block the access to the active site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The CBM20 domain is involved in binding to starch.</text>
    </comment>
    <comment type="PTM">
        <text evidence="7">O-mannosylated.</text>
    </comment>
    <comment type="biotechnology">
        <text evidence="2">Starch-active PMOs provide an expanded perspective on studies of starch metabolism and may have potential in the food and starch-based biofuel industries.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the polysaccharide monooxygenase AA13 family.</text>
    </comment>
    <comment type="sequence caution" evidence="9">
        <conflict type="erroneous gene model prediction">
            <sequence resource="EMBL-CDS" id="EAQ71571" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="1.14.99.55" evidence="7"/>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71571.1"/>
        <property type="status" value="ALT_SEQ"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH165177">
        <property type="protein sequence ID" value="KYQ30499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846003.1">
        <property type="nucleotide sequence ID" value="XM_016990482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4J3"/>
    <dbReference type="SMR" id="A0A151V4J3"/>
    <dbReference type="STRING" id="242507.A0A151V4J3"/>
    <dbReference type="CAZy" id="AA13">
        <property type="family name" value="Auxiliary Activities 13"/>
    </dbReference>
    <dbReference type="CAZy" id="CBM20">
        <property type="family name" value="Carbohydrate-Binding Module Family 20"/>
    </dbReference>
    <dbReference type="EnsemblFungi" id="MGG_10208T0">
        <property type="protein sequence ID" value="MGG_10208T0"/>
        <property type="gene ID" value="MGG_10208"/>
    </dbReference>
    <dbReference type="GeneID" id="2681855"/>
    <dbReference type="KEGG" id="mgr:MGG_10208"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10208"/>
    <dbReference type="eggNOG" id="ENOG502QSJT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4J3"/>
    <dbReference type="OMA" id="SWKWNSF"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="BRENDA" id="1.14.99.55">
        <property type="organism ID" value="5238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05811">
        <property type="entry name" value="CBM20_glucoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000552">
        <property type="entry name" value="Related to glucoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034836">
        <property type="entry name" value="CBM20_glucoamylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15048">
        <property type="entry name" value="STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15048:SF0">
        <property type="entry name" value="STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword id="KW-0186">Copper</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0624">Polysaccharide degradation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007589984" description="AA13 family lytic polysaccharide monooxygenase A">
        <location>
            <begin position="18"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="3">
        <location>
            <begin position="18"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="5">
        <location>
            <begin position="272"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="250"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="modified residue" description="Methylhistidine" evidence="2">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="4">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="39"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="65"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="101"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="152"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="166"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="180"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="Q2U8Y3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="Q7SCE9"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3"/>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="7">
        <source>
            <dbReference type="PubMed" id="27397613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="8">
        <source>
            <dbReference type="PubMed" id="27397613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="9"/>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KYQ30499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="378" mass="40169" checksum="3D76787EBCBD68B5" modified="2016-06-08" version="1" precursor="true">MKWSVIQALALASGVQAHGYLTFPMSRTGLNAQAGPDTCPECTILEPVTAWPDLDSAQVGRSGPCGYNARVSVDYNQPGPRWGSAPVVTYKGGDVADVQWCVDNNGDHGGMFTYRICQDQALVDKLLTPGYLPSEAEKQAAENCFRAGTLPCTDVNGQSCGYSPDCSPGQACWRNDWFTCKGFQDTKCRGVDNAPLNSCYTSIAGGYTVSSRIKIPNYVSNHTLLSFKWNSFQTPQIYLTCADIKITAPDSQSPPTTTTTSTPASPPPTSCATPAASVAVTFRSKTTTSVGQTVKIAGSIAQLGGWDASKAPALSASQYTSSNPLWTTTISLPAGATFEYKFIRVESSGAVTYESGANRVYTVPRDCAGTATVDTAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>A4R2Z0</accession>
    <name>A4R2Z0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxin 22-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709168.1">
        <property type="nucleotide sequence ID" value="XM_003709120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4R2Z0"/>
    <dbReference type="STRING" id="242507.A4R2Z0"/>
    <dbReference type="GeneID" id="2681488"/>
    <dbReference type="KEGG" id="mgr:MGG_02391"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02391"/>
    <dbReference type="eggNOG" id="ENOG502SHU3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025740_0_0_1"/>
    <dbReference type="InParanoid" id="A4R2Z0"/>
    <dbReference type="OMA" id="VAAWIWS"/>
    <dbReference type="OrthoDB" id="5327700at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="44402" checksum="DACEDB21BA1D4ECF" modified="2007-05-15" version="1">MSDQRGSSRRHGVWTHWVPLVLTVTVATVGIAAWAWSQRSDDDDEVSNRPNNGGSNNNPSSYPQKHQQGDQHLDYENADYGDNPPYGAANRSVDVKADGHSEGVGGWGTRMSGALRRTPSPQQFLDSAGKTVAAGVAAAGAAVGSALAAIREEDKNAYADHETWSEEADAKKKDKGSSSKHGSKKRKTVAIVVSADMHMDDIDEDDFHEHASLLSHIPKTVDFSKIKLFVLIYAPGLKEAGADASGNLPPSLSSSFSNISHNQAQSPKEEKTPLQAATASSPAFNTIYSQALALVEKETMILPFTSSTGHSHILRHLQPDVVYLQESLSGEEGIVVSQMQAWLNKEIILVVGADSGSGGLADSESEVERPSKDVKKWWQREERVGRGRGVIVVDGMRVTDDWTRRVQGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKY0</accession>
    <name>G4MKY0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromatin structure-remodeling complex protein RSC7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05378</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710227.1">
        <property type="nucleotide sequence ID" value="XM_003710179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKY0"/>
    <dbReference type="STRING" id="242507.G4MKY0"/>
    <dbReference type="GeneID" id="2676190"/>
    <dbReference type="KEGG" id="mgr:MGG_05378"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05378"/>
    <dbReference type="eggNOG" id="ENOG502QW07">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022149_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKY0"/>
    <dbReference type="OMA" id="SANWQFE"/>
    <dbReference type="OrthoDB" id="5598844at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013933">
        <property type="entry name" value="CRC_Rsc7/Swp82"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF3">
        <property type="entry name" value="CHROMATIN STRUCTURE-REMODELING COMPLEX SUBUNIT RSC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08624">
        <property type="entry name" value="CRC_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA57615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="562" mass="62863" checksum="85A166584B15DD37" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML20</accession>
    <name>G4ML20_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711059.1">
        <property type="nucleotide sequence ID" value="XM_003711011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML20"/>
    <dbReference type="STRING" id="242507.G4ML20"/>
    <dbReference type="GeneID" id="2678865"/>
    <dbReference type="KEGG" id="mgr:MGG_08629"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08629"/>
    <dbReference type="eggNOG" id="ENOG502SCBF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004184_6_0_1"/>
    <dbReference type="InParanoid" id="G4ML20"/>
    <dbReference type="OMA" id="HARYWID"/>
    <dbReference type="OrthoDB" id="3548654at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052895">
        <property type="entry name" value="HetReg/Transcr_Mod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24148:SF79">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="43"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="229" mass="26248" checksum="03A74A37289E0F34" modified="2011-12-14" version="1">MEYKTLSTVKNEIRLIKIRSTPNHDSPVAFRLEHASLNDKPDYIALSYCWGDPLKRQDMQILQGLKNQNTPITYSATANLANALRELRLRGELRVWADAVCIDQKNDDERGQQVLRMDVIYRCAKKTVSYLGGPSSCNSNSSIPDLGEFFHLTTSVMWNPSRDHSAGWNAFCSLLNNNYWSRVWIIQEIAMVETVQVNERPNHTEIEAAKSAMNQAKDIDRRHQSPLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLA4</accession>
    <name>G4MLA4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710246.1">
        <property type="nucleotide sequence ID" value="XM_003710198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLA4"/>
    <dbReference type="GeneID" id="12986257"/>
    <dbReference type="KEGG" id="mgr:MGG_16346"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16346"/>
    <dbReference type="HOGENOM" id="CLU_2360128_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLA4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465216" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="11062" checksum="F480B5F5261CCA29" modified="2011-12-14" version="1">MSRYASLFKMISFLSLLSDVIAYITEPKLLTINNYQKTRTTWLGGYVAPHGYQQLSGNENRIRSHPLKIIKGWYLVTTRNNPFETRKPNPASEGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM74</accession>
    <name>G4MM74_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prion-inhibition and propagation HeLo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710367.1">
        <property type="nucleotide sequence ID" value="XM_003710319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM74"/>
    <dbReference type="GeneID" id="2676203"/>
    <dbReference type="KEGG" id="mgr:MGG_05500"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05500"/>
    <dbReference type="eggNOG" id="ENOG502RQM0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_445603_0_0_1"/>
    <dbReference type="InParanoid" id="G4MM74"/>
    <dbReference type="OMA" id="NDYLGEM"/>
    <dbReference type="OrthoDB" id="5331891at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465831" description="Prion-inhibition and propagation HeLo domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="67034" checksum="497CC807BA291C4C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMH3</accession>
    <name>G4MMH3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphatidylethanolamine-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_06844</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphatidylethanolamine-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709563.1">
        <property type="nucleotide sequence ID" value="XM_003709515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMH3"/>
    <dbReference type="SMR" id="G4MMH3"/>
    <dbReference type="STRING" id="242507.G4MMH3"/>
    <dbReference type="GeneID" id="2685017"/>
    <dbReference type="KEGG" id="mgr:MGG_06844"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06844"/>
    <dbReference type="eggNOG" id="KOG3346">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043994_4_1_1"/>
    <dbReference type="InParanoid" id="G4MMH3"/>
    <dbReference type="OMA" id="MVDPDWN"/>
    <dbReference type="OrthoDB" id="2506647at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030162">
        <property type="term" value="P:regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046578">
        <property type="term" value="P:regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001858">
        <property type="entry name" value="Phosphatidylethanolamine-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF148">
        <property type="entry name" value="CARBOXYPEPTIDASE Y INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01220">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465235" description="Phosphatidylethanolamine-binding protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="29654" checksum="BDDEE066B10A04DF" modified="2011-12-14" version="1">MRALGCIAFAAAMTPVVANMPPSEFNFPSVNNDTVLTVAYTFNGNTTVVDPGTMFGGNVARNQPQLAVDPTKFRSLADYTGQYVVIMIDPDAPSPDNPIRRSILHWLASGITQTLGGGSGRISGQRSLTNSTPATVPYAAPGPPPSSSAHRYFFYIWQQPPGFQVPSSFNPNNRANFDIENFVRETNLGAPAAANYIYVSRQDSVPMTFIASPGSEYPGGNGNAVFPRKGDGNGNGNGNGNDNGDPYNPNYPDEGAASGGIQMSNFAALISFVAMGLACLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMR7</accession>
    <name>G4MMR7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708759.1">
        <property type="nucleotide sequence ID" value="XM_003708711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMR7"/>
    <dbReference type="GeneID" id="2681640"/>
    <dbReference type="KEGG" id="mgr:MGG_02014"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02014"/>
    <dbReference type="HOGENOM" id="CLU_953383_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMR7"/>
    <dbReference type="OrthoDB" id="4744378at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="292" mass="32723" checksum="6F2C17DE1A05745A" modified="2011-12-14" version="1">MNAAHHDMALFGSWVKYQHYVQTSNSNVPRILSSQEIALAADLGSNFDFTNAFRQRLELGRDLYTGVRQNLMTILQIWDAVMDERDIFETSGSFTLHQDIQKAFIFCTDTITARVNVGSLGPQGLPNYTPTSRPPKLQICTEKLGPYYAGHGQFFADITAVGRHVQQSIGPYTEFLALSDSGDAGNIEINDEDKEETVDENEHNDEGDYTDDDDDDDDNKSDDDYQEENSENDTSRISFQAQGTPIKKGRESSLDKLVKFDMAWVNDTQGFSMGSEPDFEELSRPAPSLSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMT1</accession>
    <name>G4MMT1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_14612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708773.1">
        <property type="nucleotide sequence ID" value="XM_003708725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMT1"/>
    <dbReference type="SMR" id="G4MMT1"/>
    <dbReference type="STRING" id="242507.G4MMT1"/>
    <dbReference type="GeneID" id="5050480"/>
    <dbReference type="KEGG" id="mgr:MGG_14612"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14612"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_664060_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMT1"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="293"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="326"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="359"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA56161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="414" mass="45387" checksum="68E86C8799AA0D9D" modified="2011-12-14" version="1">MLSALPNRFYAPGGLPTPSKDHYTLCGISASLDIGQYHHQFTIGGVLTVNEKAFALTVLHSDPEEPDAKTQETSIESLVKEMVEKGAVAKNIKEINVASSTRRNSGSEKEMISGDPLDSQQPTGREHEHLGTLTRTGEEWALISIDDPGNRLPNCIEVPDHGARLYLDRVQDPEDVLAKAKVYVCSGVGSAIRASLSGPLSRMKLGSGKIIKVWTVTFIDHRKGQQLRLGDSGSWVVNPFEGIIYGHVIARAKNVGFVLPLKHVMEEIGACQLPTVAIKSPQEVFEEYAKSQNDRGSLHRAARAGDEVTVNLLIKQGANKEVEDDNGRTPLYLAIEAGHQPTVKLLIEYRADKEVKDYNCRTPLHLAVEAESEGIVELLVEHGANKEARDNHGRTPLHLAVEAGRENIMKFLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMW3</accession>
    <name>G4MMW3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3CxxC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_16016</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708805.1">
        <property type="nucleotide sequence ID" value="XM_003708757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMW3"/>
    <dbReference type="GeneID" id="12985682"/>
    <dbReference type="KEGG" id="mgr:MGG_16016"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16016"/>
    <dbReference type="InParanoid" id="G4MMW3"/>
    <dbReference type="OrthoDB" id="8121437at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027377">
        <property type="entry name" value="ZAR1/RTP1-5-like_Znf-3CxxC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13695">
        <property type="entry name" value="Zn_ribbon_3CxxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01328">
        <property type="entry name" value="zf-3CxxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="3CxxC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA56193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="107" mass="12577" checksum="D3A79E59B1AE1FFC" modified="2011-12-14" version="1" fragment="single">MGRFTCRNRQCASGGWFSRTMGIWIRQFRGGRYNAIVYSQECELCGWLGWLTLDRGSHIERVPYWLKKWAGVPVEPPPRREKRGPPHKQQLCEGCRRGLCQVGRRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN13</accession>
    <name>G4MN13_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Serine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="2">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Seryl-tRNA(Ser) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_06913</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="2"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709647.1">
        <property type="nucleotide sequence ID" value="XM_003709599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN13"/>
    <dbReference type="SMR" id="G4MN13"/>
    <dbReference type="FunCoup" id="G4MN13">
        <property type="interactions" value="800"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MN13"/>
    <dbReference type="GeneID" id="2685086"/>
    <dbReference type="KEGG" id="mgr:MGG_06913"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06913"/>
    <dbReference type="eggNOG" id="KOG2509">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023797_0_1_1"/>
    <dbReference type="InParanoid" id="G4MN13"/>
    <dbReference type="OMA" id="GYTPCFR"/>
    <dbReference type="OrthoDB" id="10264585at2759"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990825">
        <property type="term" value="F:sequence-specific mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110004">
        <property type="term" value="P:positive regulation of tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.40:FF:000003">
        <property type="entry name" value="Serine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000026">
        <property type="entry name" value="Seryl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="15">
        <location>
            <begin position="146"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="67"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="270"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="286"/>
            <end position="289"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="357"/>
            <end position="360"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for serine binding" evidence="12">
        <location>
            <position position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00058708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA57035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="497" mass="55902" checksum="B81693E205C18BB3" modified="2011-12-14" version="1">MVLDVTDFITERGGNPEKIRESQRRRHAPVEVVDEIIAMWDDHRRTQYAATQMNAQINDVQKKIGAKKKAKEDASEFLQEKIALEKAKKELIDSAAEKQKILDKKLTTIGNIVHDSVPVSDNEDNNEIIRTYCPEGLTVEKRECLSHHEVLTRLDGYDPDRGIKAVGHRGYFLRQWGVFLNQAIINFGLEFLSSKSFVPLQPPFFLLKDQMSKTAQLEQFDEELYKVVDGEADKYLIATSEQPISVYHANEWLLPQDLPLRYAGYSTCFRKEAGGHGRDVWGTFRVHQFEKVEQFCITEPEKSWEMFDEMIANSEEFYKALGLPYRIVAIVSGALNNAAAKKFDLEAWFPFQGEYKELVSCSNCTDYQSRSLEIRFGTKTQTSTKKEYVHCLNSTLTATSRTMCALLENYQTEDGFKVPEPLRKYLPGAPEFIPFTKELPKDIAAQAKALKEAKAASKSQKGAAGATGAAKQKVADAAAAATGAVSQVAEKLGETKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNH7</accession>
    <name>G4MNH7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709703.1">
        <property type="nucleotide sequence ID" value="XM_003709655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNH7"/>
    <dbReference type="GeneID" id="12985245"/>
    <dbReference type="KEGG" id="mgr:MGG_16225"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16225"/>
    <dbReference type="HOGENOM" id="CLU_2606488_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNH7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="79" mass="9034" checksum="3CCE48D103031BB8" modified="2011-12-14" version="1">MLNSKVKILFSTSLTILGRLDKRQYFLSASFSGSFPVLEESLVINETDSSTADRLSFDGCYFARFSIMKDHNRRSTISW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPA8</accession>
    <name>G4MPA8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA repair protein Rad7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709773.1">
        <property type="nucleotide sequence ID" value="XM_003709725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPA8"/>
    <dbReference type="SMR" id="G4MPA8"/>
    <dbReference type="FunCoup" id="G4MPA8">
        <property type="interactions" value="31"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MPA8"/>
    <dbReference type="GeneID" id="2685188"/>
    <dbReference type="KEGG" id="mgr:MGG_07015"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07015"/>
    <dbReference type="eggNOG" id="KOG1947">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006598_1_0_1"/>
    <dbReference type="InParanoid" id="G4MPA8"/>
    <dbReference type="OMA" id="ACRHISR"/>
    <dbReference type="OrthoDB" id="1924287at2759"/>
    <dbReference type="PHI-base" id="PHI:890"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000601">
        <property type="entry name" value="DNA repair protein Rad7, protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056451">
        <property type="entry name" value="Znf_Tbcl_Rhp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF234">
        <property type="entry name" value="RNI-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23550">
        <property type="entry name" value="zf_Tbcl_Rhp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair protein rhp7 treble clef" evidence="2">
        <location>
            <begin position="165"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="635" mass="69998" checksum="2C464E99EA3C3EAA" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPE3</accession>
    <name>G4MPE3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rRNA 2'-O-methyltransferase fibrillarin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Histone-glutamine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_09195</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-glutaminyl-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[histone H2A] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50904"/>
            <dbReference type="Rhea" id="RHEA-COMP:12837"/>
            <dbReference type="Rhea" id="RHEA-COMP:12839"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709808.1">
        <property type="nucleotide sequence ID" value="XM_003709760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPE3"/>
    <dbReference type="SMR" id="G4MPE3"/>
    <dbReference type="FunCoup" id="G4MPE3">
        <property type="interactions" value="1023"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MPE3"/>
    <dbReference type="GeneID" id="2680291"/>
    <dbReference type="KEGG" id="mgr:MGG_09195"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09195"/>
    <dbReference type="eggNOG" id="KOG1596">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059055_1_0_1"/>
    <dbReference type="InParanoid" id="G4MPE3"/>
    <dbReference type="OMA" id="WNPNKSK"/>
    <dbReference type="OrthoDB" id="1859733at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000452">
        <property type="term" value="P:snoRNA guided rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000056">
        <property type="entry name" value="Fibrillarin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000001">
        <property type="entry name" value="Fibrillarin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003276">
        <property type="entry name" value="PRK04266.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF17">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006540">
        <property type="entry name" value="Nop17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="43"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA57196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="321" mass="33786" checksum="092C31E278E4AF92" modified="2011-12-14" version="1">MAFTPRGRGAPRGGGGFRGGDRGGRGGGGRGGGSFRGGDRGGRGGGRGGPRGGRGGPARGGRGGGRGGKPGAAGGKKVIVEPHRHKGVFVARGGKEDLLATINLVPGESVYGEKRIAVENSNKGDDDTPATKTEYRIWNPFRSKLAAGILGGMDNIFMKPGAKVLYLGAASGTSVSHVADLVGPTGNVYAVEFSHRSGRDLINMATKRTNVIPIVEDARHPLKYRMVVPMVDCIFADVAQPDQARIVALNASLFLKKGGGTCISIKANCIDSTAPAEEVFASEVEKLRAEKFFPKEQLTLEPYERDHAMVTAVYQQREFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQH4</accession>
    <name>G4MQH4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carboxypeptidase S1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_02309</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709076.1">
        <property type="nucleotide sequence ID" value="XM_003709028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQH4"/>
    <dbReference type="SMR" id="G4MQH4"/>
    <dbReference type="STRING" id="242507.G4MQH4"/>
    <dbReference type="MEROPS" id="S10.016"/>
    <dbReference type="GeneID" id="2681406"/>
    <dbReference type="KEGG" id="mgr:MGG_02309"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02309"/>
    <dbReference type="eggNOG" id="KOG1282">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008523_10_3_1"/>
    <dbReference type="InParanoid" id="G4MQH4"/>
    <dbReference type="OMA" id="FQEFPGY"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF189">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465986" evidence="7">
        <location>
            <begin position="22"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA56464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="634" mass="69697" checksum="20C0288DD9210468" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQI7</accession>
    <name>G4MQI7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pantothenate transporter liz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_02319</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Allantoate permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709089.1">
        <property type="nucleotide sequence ID" value="XM_003709041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQI7"/>
    <dbReference type="SMR" id="G4MQI7"/>
    <dbReference type="FunCoup" id="G4MQI7">
        <property type="interactions" value="15"/>
    </dbReference>
    <dbReference type="GeneID" id="2681416"/>
    <dbReference type="KEGG" id="mgr:MGG_02319"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02319"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_4_2_1"/>
    <dbReference type="InParanoid" id="G4MQI7"/>
    <dbReference type="OMA" id="FTWVCFM"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000386">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000065">
        <property type="entry name" value="Putative MFS pantothenate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF39">
        <property type="entry name" value="TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="75"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00037968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA56477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="503" mass="56547" checksum="0F44B532F4CA9CD1" modified="2011-12-14" version="1">MVTTDPKHPVCLPIDTSDGAFDSKGTNSDYSSSSPLSVLADVNEQPKKSWRSTIWDTLDKPKEERRFLFKLDAVILTMASLGYFIKNLDQINITSAFVSGMKEDLGLHGNELNYMITCWTVGYVIGEIPSNMLLTRIRPSIWIPTCEVIWSVLTILLAKCTSATQIYVLRFFIGLAESAFYPGMQYVIGSWYRKDELAKRSCIFHASGNIGGMFSGYLMAAAYTLNDTNGFRGWQWLFIINTVVSLPIAIAGYFFFPDVPEITKAWWLTEAEIDIARKRMVLEGRANRAPYTKQKFKKIFSSWHIYLLPLLYILFNNGGGYGGQPVFALWLKSEGYGIVAINSYPTIAAAIAVVMTLAYAWTSDTVFRGARWPPIVFAGCFKIVTETSLAVWSIPVGWKWFCFIFGSVSSGISGLTFAWAHEICSDDNEERALVVATMNQMAYVVQAWLPLLIWQQVDQPRYQKGFITMVFIAAGMIATAFAIRLLHHRERARKAKEAEQGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQM1</accession>
    <name>G4MQM1_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16103</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003709075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQM1"/>
    <dbReference type="GeneID" id="12984364"/>
    <dbReference type="KEGG" id="mgr:MGG_16103"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16103"/>
    <dbReference type="InParanoid" id="G4MQM1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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        </location>
    </feature>
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    </feature>
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        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
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            <end position="92"/>
        </location>
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        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="199" mass="21076" checksum="90B5F881138AA51C" modified="2011-12-14" version="1" fragment="single">MSPRKNYGPPIRQSQRVTNANSAKPDNLASGTATPNTEGSDQNGEITVAPVSPEPVEPAPTSANTEPEEPVEPQYDTEQDQPVDSIEVDGSYEYESVSEHSGEARSPPHQPSAKTSDGRNEIPKFPSRAPSPAAQMRSEMANESENTTGQATITQSHLQDLLATIAQLKDQLATQNNSTSNGARGVTPFNSAFGGTSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR79</accession>
    <name>G4MR79_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nab2-like CCCH zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_09923</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZC3H14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710023.1">
        <property type="nucleotide sequence ID" value="XM_003709975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR79"/>
    <dbReference type="SMR" id="G4MR79"/>
    <dbReference type="STRING" id="242507.G4MR79"/>
    <dbReference type="GeneID" id="2680893"/>
    <dbReference type="KEGG" id="mgr:MGG_09923"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09923"/>
    <dbReference type="eggNOG" id="KOG3702">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027088_1_0_1"/>
    <dbReference type="InParanoid" id="G4MR79"/>
    <dbReference type="OMA" id="CPYAHQS"/>
    <dbReference type="OrthoDB" id="438553at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043488">
        <property type="term" value="P:regulation of mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.40:FF:000001">
        <property type="entry name" value="Nuclear polyadenylated RNA-binding protein nab2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.30:FF:000002">
        <property type="entry name" value="Nuclear polyadenylated RNA-binding protein Nab2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.40:FF:000002">
        <property type="entry name" value="Nuclear polyadenylated RNA-binding protein Nab2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.40">
        <property type="entry name" value="Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055046">
        <property type="entry name" value="Nab2-like_Znf-CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040366">
        <property type="entry name" value="Nab2/ZC3H14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043094">
        <property type="entry name" value="Nab2/ZC3H14_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738:SF29">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22683">
        <property type="entry name" value="Nab2-like_zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nab2-like CCCH zinc finger" evidence="9">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="172"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="299"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="494"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA57411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="520" mass="55839" checksum="FC9CA3A0CFF069D7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRN1</accession>
    <name>G4MRN1_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">PRO41 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710066.1">
        <property type="nucleotide sequence ID" value="XM_003710018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRN1"/>
    <dbReference type="SMR" id="G4MRN1"/>
    <dbReference type="STRING" id="242507.G4MRN1"/>
    <dbReference type="GeneID" id="2680926"/>
    <dbReference type="KEGG" id="mgr:MGG_09956"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09956"/>
    <dbReference type="eggNOG" id="ENOG502S16N">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_132815_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRN1"/>
    <dbReference type="OMA" id="AYFWAYS"/>
    <dbReference type="OrthoDB" id="2110422at2759"/>
    <dbReference type="PHI-base" id="PHI:7318"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056144">
        <property type="entry name" value="DUF7727"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40629">
        <property type="entry name" value="PRO41 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40629:SF1">
        <property type="entry name" value="PRO41 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24853">
        <property type="entry name" value="DUF7727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7727" evidence="2">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="144" mass="15911" checksum="41A9295FDC0E9694" modified="2011-12-14" version="1">MGRLIKNHWARLIVLSAATYQVAAGLESYFWPKIFFDFLTHSLDGAVRPVPVLQTVNILLGFLMLAWEWPLGAIAGSGFHRSLELRLAIIPVAAISAGLIYQGTNAAVYYLIGMAVYFWAYSEGEIICAKPWTLPQRGGRGARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRT7</accession>
    <name>G4MRT7_PYRO7</name>
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        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710914.1">
        <property type="nucleotide sequence ID" value="XM_003710866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRT7"/>
    <dbReference type="STRING" id="242507.G4MRT7"/>
    <dbReference type="GeneID" id="2677927"/>
    <dbReference type="KEGG" id="mgr:MGG_04564"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04564"/>
    <dbReference type="eggNOG" id="ENOG502QSII">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020417_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRT7"/>
    <dbReference type="OMA" id="KHIHFKE"/>
    <dbReference type="OrthoDB" id="5563539at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052292">
        <property type="entry name" value="Glucose_repression_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051:SF1">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="514"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="557" mass="61035" checksum="C3195E6A766CEB62" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRY2</accession>
    <name>G4MRY2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">25S rRNA (Uridine(2843)-N(3))-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="GeneID" id="2681566"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_02469"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="68"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="51"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="EHA56651.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="42271" checksum="F7582D898C911AD0" modified="2011-12-14" version="1">MHKPINRTGSFGGNVSMGKPAPPKGNRPTRNTQSQPKKQTQTTKTTKKQTPAPERPARSVDKPNTNLISLPDQQKMLNLFSQAFNAELTSPDFTNTLQAVKQGLFDRDFERVFGDEANLRVYAARYSPTRALGYAEVLSGIFEHLELLLPAETGPDEKTPAILNMVSIGGGAAEVAAFAAYLSQAPDRSGAVTLIDSGPWGAIVDSLASHVTTPPILPQWANAEAMANNRSLIEPARLAAKFLQKDVLSSELVGIFPDEGPCLVTLFFTLNELFTAGGIGKTTQFLLDVTAVIPSGSLLLVVDSPGSYSEATVGKEAKKYPMLWLLDKVLATAEDCTWQKMESQESRWFRLPEKLTYPIPLENMRFQMHLYRAKKPVFQAKSNSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS87</accession>
    <name>G4MS87_PYRO7</name>
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            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="EHA58345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710957.1">
        <property type="nucleotide sequence ID" value="XM_003710909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS87"/>
    <dbReference type="STRING" id="242507.G4MS87"/>
    <dbReference type="GeneID" id="12986869"/>
    <dbReference type="KEGG" id="mgr:MGG_15299"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15299"/>
    <dbReference type="eggNOG" id="ENOG502RYRH">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002903_1_0_1"/>
    <dbReference type="InParanoid" id="G4MS87"/>
    <dbReference type="OMA" id="QITWTSH"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF186">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="206"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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            <end position="232"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA58345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="630" mass="69182" checksum="E5AAAC9538063DA1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTE6</accession>
    <name>G4MTE6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714504.1">
        <property type="nucleotide sequence ID" value="XM_003714456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTE6"/>
    <dbReference type="GeneID" id="12984684"/>
    <dbReference type="KEGG" id="mgr:MGG_15729"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15729"/>
    <dbReference type="HOGENOM" id="CLU_2223766_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTE6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="106" mass="11602" checksum="9AEEDCC8866FDF3F" modified="2011-12-14" version="1">MFEWDEETKEIGNPEARTSLAYIQANVPRYRTGSHQWPTAKELAAAPSPRTTGASTKNEAEPDAKASWESSLSCSEDYLGMVPYGKAGGHGWSRSDRRLAYGSGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUF6</accession>
    <name>G4MUF6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714650.1">
        <property type="nucleotide sequence ID" value="XM_003714602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUF6"/>
    <dbReference type="GeneID" id="12984707"/>
    <dbReference type="KEGG" id="mgr:MGG_15752"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15752"/>
    <dbReference type="HOGENOM" id="CLU_2722691_0_0_1"/>
    <dbReference type="InParanoid" id="G4MUF6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="72" mass="8400" checksum="AFD6EF4773C47DEA" modified="2011-12-14" version="1">MHYPLCFVFFIERQFEQTATTISNRSTEIVSVRPTNEEYTRCFGGCGSSCRLYKQSKVIDRADSDQWSQPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVC2</accession>
    <name>G4MVC2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SUN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_11149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUN family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714751.1">
        <property type="nucleotide sequence ID" value="XM_003714703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVC2"/>
    <dbReference type="FunCoup" id="G4MVC2">
        <property type="interactions" value="5"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MVC2"/>
    <dbReference type="GeneID" id="5051124"/>
    <dbReference type="KEGG" id="mgr:MGG_11149"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11149"/>
    <dbReference type="eggNOG" id="ENOG502QWHV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026108_2_0_1"/>
    <dbReference type="InParanoid" id="G4MVC2"/>
    <dbReference type="OMA" id="FGVKIEC"/>
    <dbReference type="OrthoDB" id="5554151at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053088">
        <property type="entry name" value="Beta-glucosidase/SUN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005556">
        <property type="entry name" value="SUN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31654">
        <property type="entry name" value="SECRETED BETA-GLUCOSIDASE ADG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31654:SF0">
        <property type="entry name" value="SECRETED BETA-GLUCOSIDASE ADG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03856">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="355"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="418"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="442"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="50569" checksum="1D71448C6227FFC8" modified="2011-12-14" version="1">MRPRKTLVVTYSRFNPISLAQSDITMKTATLGAALLLLGVQQCAATSGHRSLHRQFEKRHGHNHLPTRSFEADLRSPESEESGNISEVRKRGSSCSLPDDDDSLVRITDTRNDNQGFAMSPDQTCEDGMYCPFACKPGMLMNQWKEGTSFKPVESMQGGLYCDNGKPKKPFPSKPYCVQGTGTVKAVNKCGKVVSFCQTVLPGNEAMLIPTEVSGSTTLAVPGPDYWAGTAAHFYINPPGVSADQGCRWGSDANDVGNWSPYVAGANTVSDGRTFVQLSWNPIYEDSKWSSKKPSFGVKIECDGDCNGLPCEINPAKTGLKNVNSKTAASGAGGASFCVVTVSKGSSANIVLFNTDGSTGDSSSSEEPKKTTTSSSSSTPSSTSTTAPPSSYAKASYTTSSISLTIPTVRPGIFQENSTSSTDSSSWSGSASTTKFDSTQGSSSTSSAASPSSTNDGAQRDKGGAAMAGLVIAIVAAAWMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVD0</accession>
    <name>G4MVD0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex protein EXO70</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_01760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Bud</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Bud neck</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the EXO70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714759.1">
        <property type="nucleotide sequence ID" value="XM_003714711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVD0"/>
    <dbReference type="SMR" id="G4MVD0"/>
    <dbReference type="FunCoup" id="G4MVD0">
        <property type="interactions" value="124"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MVD0"/>
    <dbReference type="GeneID" id="2679605"/>
    <dbReference type="KEGG" id="mgr:MGG_01760"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01760"/>
    <dbReference type="eggNOG" id="KOG2344">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010236_4_2_1"/>
    <dbReference type="InParanoid" id="G4MVD0"/>
    <dbReference type="OMA" id="GIIRAGP"/>
    <dbReference type="OrthoDB" id="1922221at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.170">
        <property type="entry name" value="Exocyst complex component Exo70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004140">
        <property type="entry name" value="Exo70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046364">
        <property type="entry name" value="Exo70_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12542:SF41">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12542">
        <property type="entry name" value="EXOCYST COMPLEX PROTEIN EXO70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03081">
        <property type="entry name" value="Exo70_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20669">
        <property type="entry name" value="Exo70_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex subunit Exo70 C-terminal" evidence="5">
        <location>
            <begin position="250"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA54952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="632" mass="70041" checksum="1124C7A1A9EFB4D2" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MW22</accession>
    <name>G4MW22_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713982.1">
        <property type="nucleotide sequence ID" value="XM_003713934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MW22"/>
    <dbReference type="GeneID" id="12987348"/>
    <dbReference type="KEGG" id="mgr:MGG_15616"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15616"/>
    <dbReference type="HOGENOM" id="CLU_2868107_0_0_1"/>
    <dbReference type="InParanoid" id="G4MW22"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="64" mass="7644" checksum="F23954A4BB4FDEF6" modified="2011-12-14" version="1">MFTMIVTGTKSSVSGMRNCVVTCCYDQDWYRHDWARMREVSGTQARINQEARTKDRKREHEVTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWD4</accession>
    <name>G4MWD4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_08360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LovG family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715701.1">
        <property type="nucleotide sequence ID" value="XM_003715653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWD4"/>
    <dbReference type="SMR" id="G4MWD4"/>
    <dbReference type="GeneID" id="2678498"/>
    <dbReference type="KEGG" id="mgr:MGG_08360"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08360"/>
    <dbReference type="eggNOG" id="ENOG502SPW1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051938_0_2_1"/>
    <dbReference type="InParanoid" id="G4MWD4"/>
    <dbReference type="OMA" id="SGNIFRM"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF3">
        <property type="entry name" value="ESTERASE DBAE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA55894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="232" mass="25208" checksum="5C61E9596713356E" modified="2011-12-14" version="1">MPPTKAILCLHGGGTSGNIFRMQLAKIRLQLKDEFEFVFMDAPYPADAGPGILPIFAAAAPFFGWFGGSSADIDGRLETINTSVRAAIEGWAASRTTLATIVGILAFSEGALAASMLLWQQERGRLPWLPVVRFAVLISCFFPDQAAAYMAADEAATGHERTLIRVPTLHLHGRQDFALARMRKLVSERCDPDTARVVDFNGEQKAIETLLQVDGDNKLMILLGFALTASPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWP3</accession>
    <name>G4MWP3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GS1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_11115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714905.1">
        <property type="nucleotide sequence ID" value="XM_003714857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWP3"/>
    <dbReference type="SMR" id="G4MWP3"/>
    <dbReference type="FunCoup" id="G4MWP3">
        <property type="interactions" value="183"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MWP3"/>
    <dbReference type="GeneID" id="5051090"/>
    <dbReference type="KEGG" id="mgr:MGG_11115"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11115"/>
    <dbReference type="eggNOG" id="KOG2914">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_13_0_1"/>
    <dbReference type="InParanoid" id="G4MWP3"/>
    <dbReference type="OMA" id="IWCPHPG"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000131">
        <property type="entry name" value="HAD superfamily hydrolase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.240:FF:000001">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901">
        <property type="entry name" value="2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18901:SF38">
        <property type="entry name" value="PSEUDOURIDINE-5'-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="30781" checksum="FDCF278B369BE8ED" modified="2011-12-14" version="1">MASTATNPPPIRACLFDMDGLLLDTEDLYTKCINVVLARYSRPNLPWSIKAKLQGRPAAEATSIFHSWADLPISNEQYLAEFSAQQREHFPTAAPLPGVEKLLADLRRARDGQDGSTAAPRVHLALATSSTQVNFRLKSAHLAELFSVFRPEHRVLGDDPRIPRGRGKPLPDIYLVALAALNASLPAGEAEIRPEECLVFEDSVPGVEAGRRAGMQVVWVPHPMLKKEYEGREDEILAGRMGEAGDVADGGKVGEIGDGWGLYLETLENFPYDKFGIQIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWQ5</accession>
    <name>G4MWQ5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714917.1">
        <property type="nucleotide sequence ID" value="XM_003714869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWQ5"/>
    <dbReference type="GeneID" id="12985448"/>
    <dbReference type="KEGG" id="mgr:MGG_15332"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15332"/>
    <dbReference type="HOGENOM" id="CLU_2427444_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWQ5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA55110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="91" mass="10079" checksum="F23B38A44BA4B8DB" modified="2011-12-14" version="1">MKSRQLPSDESSVRLKARGRVSEQTFFKTRAGLEVYVKPTEVGLELPQQQAFPNPTIHLAQLPKMDILDGVGANIAKLLYSGNLLTSGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWV3</accession>
    <name>G4MWV3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715764.1">
        <property type="nucleotide sequence ID" value="XM_003715716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWV3"/>
    <dbReference type="GeneID" id="5051065"/>
    <dbReference type="KEGG" id="mgr:MGG_12471"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12471"/>
    <dbReference type="eggNOG" id="ENOG502T3CW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1008571_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWV3"/>
    <dbReference type="OMA" id="ANARWQM"/>
    <dbReference type="OrthoDB" id="3539922at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="276" mass="32247" checksum="CA53C5872FDAF835" modified="2011-12-14" version="1">MSDSRRHSSYGDRRRRYYEEDESDDGYDDNSYYHYDPRHHGRDDRRRTRDRSVHFDDTPRSYDYLPPKYSYSNSSSSSSSSRRRGDEVSRARSTHHRRDDSVERKRHRDASERYRNSDRRRHRSHDQPRREHHRHRDEERGRERDRERDRDRDARHRQRPAHRRHSTGGEMRANKSQRRSRSRSRSSSDDEGRGKSLSRLAASAALTAGGVEALKIRNDPGSWVGSKGRRVVTAALGAAAINRVVDNGMRDHPVRQKAGAALGGVILNKVLNGSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXB1</accession>
    <name>G4MXB1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitotic spindle checkpoint component mad2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_08269</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715816.1">
        <property type="nucleotide sequence ID" value="XM_003715768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXB1"/>
    <dbReference type="SMR" id="G4MXB1"/>
    <dbReference type="FunCoup" id="G4MXB1">
        <property type="interactions" value="1044"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MXB1"/>
    <dbReference type="GeneID" id="2678561"/>
    <dbReference type="KEGG" id="mgr:MGG_08269"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08269"/>
    <dbReference type="eggNOG" id="KOG3285">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072097_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXB1"/>
    <dbReference type="OMA" id="WQFDVEI"/>
    <dbReference type="OrthoDB" id="1806at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033597">
        <property type="term" value="C:mitotic checkpoint complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990498">
        <property type="term" value="C:mitotic spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905318">
        <property type="term" value="P:meiosis I spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.900.10:FF:000002">
        <property type="entry name" value="Mitotic spindle assembly checkpoint protein MAD2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF11">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="8">
        <location>
            <begin position="21"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="234" mass="25695" checksum="FE476B23823460F9" modified="2011-12-14" version="1">MADKAAEKDKDKSKVHKLSLKGSAKLVAEFFQYSIHTILFQRGVYPAEDFTAVKKYGLNMLVSADDQVKAYIKKIMSQLDRWMVKGKISKLVIVITDKDTGEHVERWQFDVQIFGGSSKKSKSSSKSAASASAGQENSSAASDAAQAPEKTEAEIQAEIAAIFRQITASVTFLPQLAGDCTFNVLVYADADSEVPVEWGDSDAKEIENGERVQLRGFSTASHRVDTLVSYRLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXE6</accession>
    <name>G4MXE6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Levanase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_10748</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713283.1">
        <property type="nucleotide sequence ID" value="XM_003713235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXE6"/>
    <dbReference type="SMR" id="G4MXE6"/>
    <dbReference type="STRING" id="242507.G4MXE6"/>
    <dbReference type="GeneID" id="2676270"/>
    <dbReference type="KEGG" id="mgr:MGG_10748"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10748"/>
    <dbReference type="eggNOG" id="KOG0228">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013784_3_0_1"/>
    <dbReference type="InParanoid" id="G4MXE6"/>
    <dbReference type="OMA" id="HWARSEH"/>
    <dbReference type="OrthoDB" id="202537at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18621">
        <property type="entry name" value="GH32_XdINV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800">
        <property type="entry name" value="EXOINULINASE INUD (AFU_ORTHOLOGUE AFUA_5G00480)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42800:SF3">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 32 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465746" description="Levanase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="6">
        <location>
            <begin position="53"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="7">
        <location>
            <begin position="469"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA53476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="74344" checksum="2FB03CCC1CF74784" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXL3</accession>
    <name>G4MXL3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714151.1">
        <property type="nucleotide sequence ID" value="XM_003714103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXL3"/>
    <dbReference type="GeneID" id="12984604"/>
    <dbReference type="KEGG" id="mgr:MGG_15653"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15653"/>
    <dbReference type="HOGENOM" id="CLU_2688286_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXL3"/>
    <dbReference type="OMA" id="MERGPID"/>
    <dbReference type="OrthoDB" id="10460582at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="74" mass="8421" checksum="3A6D84D11A3EEB3E" modified="2011-12-14" version="1">MSQNRIPPPLFRDLLTPGPYLVTTDRRLLSVLSLPDYFSATKKNPIKALIMERGPIDQSSSHQSSHFIKQHADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYM3</accession>
    <name>G4MYM3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">chitinase</fullName>
            <ecNumber evidence="4">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_11231</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="4"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714255.1">
        <property type="nucleotide sequence ID" value="XM_003714207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYM3"/>
    <dbReference type="SMR" id="G4MYM3"/>
    <dbReference type="STRING" id="242507.G4MYM3"/>
    <dbReference type="GeneID" id="5051199"/>
    <dbReference type="KEGG" id="mgr:MGG_11231"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11231"/>
    <dbReference type="eggNOG" id="KOG2806">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002833_1_2_1"/>
    <dbReference type="InParanoid" id="G4MYM3"/>
    <dbReference type="OMA" id="NPMTYDF"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000009">
        <property type="entry name" value="CTS2p putative chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF228">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="GH18" evidence="12">
        <location>
            <begin position="21"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA54448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="359" mass="38655" checksum="9B2B713E34F81AD8" modified="2011-12-14" version="1">MSSSSASRKSRKSRSGSSVMYTNAVYFPNHHIYKGDTPGQLNYSCISHVFYAHAQVSSDGSVLLSDEWADAGASCDGVKGGLGSLMYLKQKHPHLLVVLSVGGGNSSEIFPHVAASAVRRDNFARSAQGLVDASGLDGIDVDWEYPSDPQQGADFVALLAAARLYLTEDRYILTAALPAGISVLQNINLAMAADYLDYINIKAYDLYGSWTHKCGHHAQLYAKGKDESSGSSTVHYLLSRKVPAKKILLGIPIYGRSFLNTTGPGHRFKGTGGEHGVFEYRQLPRKGTREQVDKGLVAAQCVGGDGGFVTYDNPETVKMKATYCKQKGLGGLFYWAGPADSKDSKRSLIAAGFRTLHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYM6</accession>
    <name>G4MYM6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">General negative regulator of transcription subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_11229</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714258.1">
        <property type="nucleotide sequence ID" value="XM_003714210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYM6"/>
    <dbReference type="SMR" id="G4MYM6"/>
    <dbReference type="STRING" id="242507.G4MYM6"/>
    <dbReference type="GeneID" id="5051198"/>
    <dbReference type="KEGG" id="mgr:MGG_11229"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11229"/>
    <dbReference type="eggNOG" id="KOG2068">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001793_1_0_1"/>
    <dbReference type="InParanoid" id="G4MYM6"/>
    <dbReference type="OMA" id="CNNRNCM"/>
    <dbReference type="OrthoDB" id="1923159at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010557">
        <property type="term" value="P:positive regulation of macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051254">
        <property type="term" value="P:positive regulation of RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16618">
        <property type="entry name" value="mRING-HC-C4C4_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12438">
        <property type="entry name" value="RRM_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000257">
        <property type="entry name" value="CCR4-NOT core complex subunit Not4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000006">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034261">
        <property type="entry name" value="CNOT4_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039780">
        <property type="entry name" value="Mot2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039515">
        <property type="entry name" value="NOT4_mRING-HC-C4C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14570">
        <property type="entry name" value="zf-RING_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="15"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="121"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="246"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="417"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="548"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="350"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="471"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="549"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA54451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="729" mass="78573" checksum="FD16DBFA9CAE2C7C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ02</accession>
    <name>G4MZ02_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphorus acquisition-controlling protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Young S.K."/>
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                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
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                <person name="Arachchi H.M."/>
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                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
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                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
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                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
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                <person name="Goldberg J."/>
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                <person name="Gujja S."/>
                <person name="Heiman D."/>
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                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51469.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
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            <taxon>Pezizomycotina</taxon>
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            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003712095.1"/>
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    <dbReference type="GeneID" id="2684183"/>
    <dbReference type="KEGG" id="mgr:MGG_05792"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05792"/>
    <dbReference type="HOGENOM" id="CLU_2061973_0_0_1"/>
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    </feature>
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        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="119" mass="12499" checksum="58B3DBC7ED6032A2" modified="2011-12-14" version="1">MRSIFIIALASLARMTASAPGAAKSDHTVEIVQQRAEQSIAVPQKEVELQSVEIRDWEPPKVPKTQPSQGQPKTGQSPKNSGTGAGYGDMPSAGSCLVSLINIEVFAVAAGVAMATYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2G3</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711699.1">
        <property type="nucleotide sequence ID" value="XM_003711651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3R8"/>
    <dbReference type="GeneID" id="2684105"/>
    <dbReference type="KEGG" id="mgr:MGG_05870"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05870"/>
    <dbReference type="HOGENOM" id="CLU_1098673_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3R8"/>
    <dbReference type="OMA" id="ELIWALT"/>
    <dbReference type="OrthoDB" id="10314625at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="253" mass="28317" checksum="673FA42937E60AAD" modified="2011-12-14" version="1">MAGWPTQRNMWQTGDSAEKAADEENDEVLCRPPRVSTATEAGSWQYSEDALAKTVECSRLVTPGRRLLVLLDEAGRAFTGYKDDCTAPQGLESYHVVRWLHDWRMNREGKLDEDELIWALTGKQTRFSGTLVQMISNMKLAQDKLLRQYALAEKLYGSLGAIRAVASSVEIRSNIQDHLLLSSGKRGAQRMGATEEVPKAQDQAGKAHTQISTGSENCLVRDRTQIEFDRWSEDVAAKKETWAAMKAKRKAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3U6</accession>
    <name>G4N3U6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylglucosaminylphosphatidylinositol deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIGL family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.89" evidence="2"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712526.1">
        <property type="nucleotide sequence ID" value="XM_003712478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3U6"/>
    <dbReference type="SMR" id="G4N3U6"/>
    <dbReference type="FunCoup" id="G4N3U6">
        <property type="interactions" value="542"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N3U6"/>
    <dbReference type="GeneID" id="2675729"/>
    <dbReference type="KEGG" id="mgr:MGG_05020"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05020"/>
    <dbReference type="eggNOG" id="KOG3332">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034979_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3U6"/>
    <dbReference type="OMA" id="YVLESVN"/>
    <dbReference type="OrthoDB" id="440160at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000225">
        <property type="term" value="F:N-acetylglucosaminylphosphatidylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993:SF11">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="285" mass="30661" checksum="9422F33F2B5B0C5C" modified="2011-12-14" version="1">MSTTLLTAGLLVLLAPCLYIYTASVAATRFPALRNKRICLLIAHPDDEAMFFAPTVLALTRPETGNHVKILCLSSGNADGLGETRKKELVKSGMLLGLRNEDDVFVIESDAFQDSMTATWDATAISSLLTSAFVPNPAAGAMIDVLVTFDKGGVSSHPNHISLYHGARAFVSSGSAVDLYTLTSVPFLRKYASIIDAFMTLAMSWGLQGVSEAKSPERLVFMNSLMPGKAQEGGGSNDGGASYGTAWRAMTEAHKSQMVWFRYGWITLSRYMVVNDLKLEGTSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4D3</accession>
    <name>G4N4D3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_05086</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712608.1">
        <property type="nucleotide sequence ID" value="XM_003712560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4D3"/>
    <dbReference type="GeneID" id="2675659"/>
    <dbReference type="KEGG" id="mgr:MGG_05086"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05086"/>
    <dbReference type="eggNOG" id="ENOG502SXF6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_383593_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4D3"/>
    <dbReference type="OMA" id="DSSENMI"/>
    <dbReference type="OrthoDB" id="5226631at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053083">
        <property type="entry name" value="TF_kinase-domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305">
        <property type="entry name" value="SI:DKEY-192D15.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305:SF24">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE C03B1.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="278"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="689"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="697"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="708"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="721" mass="80698" checksum="1720A5DE7674B350" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5E1</accession>
    <name>G4N5E1_PYRO7</name>
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        <submittedName>
            <fullName evidence="5">60S ribosomal protein L32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_05248</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712805.1">
        <property type="nucleotide sequence ID" value="XM_003712757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5E1"/>
    <dbReference type="SMR" id="G4N5E1"/>
    <dbReference type="FunCoup" id="G4N5E1">
        <property type="interactions" value="982"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5E1"/>
    <dbReference type="GeneID" id="2675595"/>
    <dbReference type="KEGG" id="mgr:MGG_05248"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05248"/>
    <dbReference type="eggNOG" id="KOG0878">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071479_4_0_1"/>
    <dbReference type="InParanoid" id="G4N5E1"/>
    <dbReference type="OMA" id="HPSGYEE"/>
    <dbReference type="OrthoDB" id="268693at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_eL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018263">
        <property type="entry name" value="Ribosomal_eL32_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_eL32_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="Ribosomal protein L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00580">
        <property type="entry name" value="RIBOSOMAL_L32E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA52998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="131" mass="14983" checksum="ABAF99838B761129" modified="2011-12-14" version="1">MVAAAKHTAIVKKRTKSFMRHQSDRFKRVDPSWRKPKGIDNRVRRRFRGNIAMPSIGYGSNKRTKHMMPSGHKAFLVQNINDVELLLMHNQVFAAEIAHNVSSRKRIEIIARAKQLGVKVTNPKAKVTTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5L2</accession>
    <name>G4N5L2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_06138</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712012.1">
        <property type="nucleotide sequence ID" value="XM_003711964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5L2"/>
    <dbReference type="FunCoup" id="G4N5L2">
        <property type="interactions" value="875"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5L2"/>
    <dbReference type="GeneID" id="2684260"/>
    <dbReference type="KEGG" id="mgr:MGG_06138"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06138"/>
    <dbReference type="eggNOG" id="KOG2175">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004909_0_1_1"/>
    <dbReference type="InParanoid" id="G4N5L2"/>
    <dbReference type="OMA" id="ALMTHNN"/>
    <dbReference type="OrthoDB" id="27483at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072542">
        <property type="term" value="F:protein phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055236">
        <property type="entry name" value="EVH1_PP4R3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006887">
        <property type="entry name" value="P4R3-like_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051137">
        <property type="entry name" value="PP4R3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318">
        <property type="entry name" value="ATP SYNTHASE GAMMA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22972">
        <property type="entry name" value="EVH1_PP4R3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PH domain-like"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        </location>
    </feature>
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    </feature>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04802"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA52212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5M1</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
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                <person name="Li W."/>
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                <person name="Kim S."/>
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                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
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                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
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    <dbReference type="AlphaFoldDB" id="G4N5M1"/>
    <dbReference type="GeneID" id="12984265"/>
    <dbReference type="KEGG" id="mgr:MGG_16765"/>
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    <dbReference type="HOGENOM" id="CLU_1855658_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5M1"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="138" mass="15370" checksum="B515748B444F624C" modified="2011-12-14" version="1">MATGHGGNTNDRPLPFKRRLAGSSGSAKLRTIARMVDSSTIGRLKLGLESICFYPLTPCLNYAHVRTSNPDSTTTPQPERQRNKNTRFVRLHLSQPDLQGIITSPSRPRWSVLLIGFHWLHTVADCRGARTSGRAYNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
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    <gene>
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    <organism evidence="10 11">
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NCF2/NOXA1 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA53032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003712791.1"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="OMA" id="MGKIEIW"/>
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        <property type="component" value="Chromosome 3"/>
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    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="FunFam" id="1.25.40.10:FF:000017">
        <property type="entry name" value="NADPH oxidase regulator NoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051864">
        <property type="entry name" value="NCF2_NOXA1"/>
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    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15175">
        <property type="entry name" value="NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15175:SF0">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN C23A1.17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="6 7" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="9">
        <location>
            <begin position="432"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="241"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="251"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="410"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="525" mass="59104" checksum="8FF12884150F7EA9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5P6</accession>
    <name>G4N5P6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Uricase</fullName>
            <ecNumber evidence="7 10">1.7.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Urate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_05283</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 10">Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 10">
            <text>urate + O2 + H2O = 5-hydroxyisourate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:21368"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="EC" id="1.7.3.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Purine metabolism; urate degradation; (S)-allantoin from urate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 10">Belongs to the uricase family.</text>
    </comment>
    <dbReference type="EC" id="1.7.3.3" evidence="7 10"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712843.1">
        <property type="nucleotide sequence ID" value="XM_003712795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5P6"/>
    <dbReference type="SMR" id="G4N5P6"/>
    <dbReference type="STRING" id="242507.G4N5P6"/>
    <dbReference type="GeneID" id="2675338"/>
    <dbReference type="KEGG" id="mgr:MGG_05283"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05283"/>
    <dbReference type="eggNOG" id="KOG1599">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048151_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5P6"/>
    <dbReference type="OMA" id="ATMYKMS"/>
    <dbReference type="OrthoDB" id="9992118at2759"/>
    <dbReference type="UniPathway" id="UPA00394">
        <property type="reaction ID" value="UER00650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004846">
        <property type="term" value="F:urate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019628">
        <property type="term" value="P:urate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00445">
        <property type="entry name" value="Uricase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Uricase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.270.10">
        <property type="entry name" value="Urate Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002042">
        <property type="entry name" value="Uricase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019842">
        <property type="entry name" value="Uricase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03383">
        <property type="entry name" value="urate_oxi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42874:SF1">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01014">
        <property type="entry name" value="Uricase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000241">
        <property type="entry name" value="Urate_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00093">
        <property type="entry name" value="URICASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00366">
        <property type="entry name" value="URICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="4 7 10" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>urate</name>
            <dbReference type="ChEBI" id="CHEBI:17775"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000241-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000241-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA53036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="295" mass="32826" checksum="4E54ED06F351EA76" modified="2011-12-14" version="1">MPSLSAARYGKDNVRVYKVHRNAETGQQSVTEMTVCCLLEGEIDASFTKADNSVVVATDSIKNTIYIKARETPVNPPELYASILGQHFIDTYPHIHTAHVDVIVHRWTRMTIDGQPHPHSFFRDGQETRTVGAVVRRGSGLALRSGIAGLSVLKSTGSAFHGFVRDEFTTLPETWDRILSTDVDCGWSWKSFPDLDAVKAIVPKFDQAWEDARSITMKTFATDDSASVQATMYKMCEQILEAAPEVEKTDYSLPNKHYFEVDLSWHKGLANTGKDAEVYVPQSGPNGLIKCEVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5X3</accession>
    <name>G4N5X3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716068.1">
        <property type="nucleotide sequence ID" value="XM_003716020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5X3"/>
    <dbReference type="GeneID" id="12986497"/>
    <dbReference type="KEGG" id="mgr:MGG_17037"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17037"/>
    <dbReference type="HOGENOM" id="CLU_2671548_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5X3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="75" mass="8471" checksum="EED0D64AC89BD8AC" modified="2011-12-14" version="1">MSDPSKTASNERRSTTVRPTSQSLTQWLDEACQSNVTLRLSTATKPASPQERVSEKRMDALAAMRQFDRDMNKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N603</accession>
    <name>G4N603_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">54S ribosomal protein L10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_06629</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716898.1">
        <property type="nucleotide sequence ID" value="XM_003716850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N603"/>
    <dbReference type="SMR" id="G4N603"/>
    <dbReference type="FunCoup" id="G4N603">
        <property type="interactions" value="583"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N603"/>
    <dbReference type="GeneID" id="2684784"/>
    <dbReference type="KEGG" id="mgr:MGG_06629"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06629"/>
    <dbReference type="eggNOG" id="KOG0846">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055188_5_0_1"/>
    <dbReference type="InParanoid" id="G4N603"/>
    <dbReference type="OMA" id="VVTRYYT"/>
    <dbReference type="OrthoDB" id="361383at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="122"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="56"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="310" mass="34243" checksum="6C84FADE517AF142" modified="2011-12-14" version="1">MPPRLPLAQAARSCRASLTTATTTPIISSTPSITTLLGALSLQTRRQASILANLRDNPGAYNKRKRVGRGPSSGYGKTAGRGQKGRKARGAVNPWFQGGQTSLLGVWGRKGFVNHRAEDLAEVNLDRLQAWIDSGRIDATQQITPREMVRSGLAARGKDGIKIIARGSEKLKTPIDIVASRVSASAIDAIEALGGKVQTRYYTKQTIQRLVRGEMVHTTEPLPVGAEHVERILTERRSQTKHMYRMPDPTSRWDIEYYRDPAHRGYLSYQLAPGDSPSLFFKVPKTFAPKVDQAEGAQKKKKDLGDNKMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6Q4</accession>
    <name>G4N6Q4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7707 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716190.1">
        <property type="nucleotide sequence ID" value="XM_003716142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6Q4"/>
    <dbReference type="GeneID" id="2676968"/>
    <dbReference type="KEGG" id="mgr:MGG_03691"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03691"/>
    <dbReference type="eggNOG" id="ENOG502S9NN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084512_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6Q4"/>
    <dbReference type="OMA" id="KNPCGAQ"/>
    <dbReference type="OrthoDB" id="2439692at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056124">
        <property type="entry name" value="DUF7707"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118">
        <property type="entry name" value="ANCHORED CELL WALL PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38118:SF2">
        <property type="entry name" value="CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24808">
        <property type="entry name" value="DUF7707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465869" description="DUF7707 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7707" evidence="2">
        <location>
            <begin position="25"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="194" mass="19588" checksum="8E82275F0EB35F45" modified="2011-12-14" version="1">MFSFRLALVAATALVAQLAAATDYPIDPPSVPLATRRNWCTSETTQCPLICLDTGSSGKPRDNSCDPMTLNYACVCSNGNSPNLTEYSLTMPYHKCTQFQVNCVAACGLADNQCSENCRVNNPCGAASPKGASASGSAAVVAPSSTSAAPNTIQTGFAGAGGSNSNTGSGANMAAPLSLGAAITALLVAPFLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4N756</accession>
    <name>G4N756_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Swi5-dependent recombination DNA repair protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716288.1">
        <property type="nucleotide sequence ID" value="XM_003716240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N756"/>
    <dbReference type="SMR" id="G4N756"/>
    <dbReference type="STRING" id="242507.G4N756"/>
    <dbReference type="GeneID" id="2676652"/>
    <dbReference type="KEGG" id="mgr:MGG_13509"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13509"/>
    <dbReference type="eggNOG" id="ENOG502SAMI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045012_0_0_1"/>
    <dbReference type="InParanoid" id="G4N756"/>
    <dbReference type="OMA" id="FTMAMML"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28527">
        <property type="entry name" value="MATING-TYPE SWITCHING PROTEIN SWI2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28527:SF1">
        <property type="entry name" value="SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="29006" checksum="62BC7432AED615DE" modified="2011-12-14" version="1">MNTPAAKRRRIEATKTLRKPFRSPLISRRGGDKDEAKTGSEKEGEEGQSSADNRTNTTATPSPLRTKVPRRAVDTRTPFKSPSVAVASSSSSFSAASGLEGKNPRPNPDPTPDGTRKAGPSSQVAAGAVVRPSDEQLKRANGDAAGAAADGDNELRHLIVKWKAASRLAAEMVFDIAKQRVDSAGGPKAWRQQQKSWDDPASGTRGSDDEEGRELGGENHYDHDGSSCDNNGRVSDDEHEPAFTIGTMLKTMNIDPTLLGYDEHEDAWID</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7F8</accession>
    <name>G4N7F8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Regulatory factor Sgt1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716336.1">
        <property type="nucleotide sequence ID" value="XM_003716288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7F8"/>
    <dbReference type="STRING" id="242507.G4N7F8"/>
    <dbReference type="GeneID" id="2676678"/>
    <dbReference type="KEGG" id="mgr:MGG_03574"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03574"/>
    <dbReference type="eggNOG" id="KOG2406">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006241_2_0_1"/>
    <dbReference type="InParanoid" id="G4N7F8"/>
    <dbReference type="OMA" id="TKDYIWQ"/>
    <dbReference type="OrthoDB" id="27237at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010770">
        <property type="entry name" value="Ecd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060:SF0">
        <property type="entry name" value="PROTEIN ECDYSONELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060">
        <property type="entry name" value="SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07093">
        <property type="entry name" value="SGT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="628"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="571"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="633"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="656" mass="71654" checksum="C31FD817B75A7FF7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7F9</accession>
    <name>G4N7F9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">RecF/RecN/SMC N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_15281</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC6 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716337.1">
        <property type="nucleotide sequence ID" value="XM_003716289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7F9"/>
    <dbReference type="SMR" id="G4N7F9"/>
    <dbReference type="FunCoup" id="G4N7F9">
        <property type="interactions" value="799"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7F9"/>
    <dbReference type="GeneID" id="12984415"/>
    <dbReference type="KEGG" id="mgr:MGG_15281"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15281"/>
    <dbReference type="eggNOG" id="KOG0250">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009063_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7F9"/>
    <dbReference type="OMA" id="MCHDHFY"/>
    <dbReference type="OrthoDB" id="10072614at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306:SF6">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="14">
        <location>
            <begin position="144"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="349"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="492"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="758"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA50018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1186" mass="135394" checksum="077E22A9CE1E7B17" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7W5</accession>
    <name>G4N7W5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717238.1">
        <property type="nucleotide sequence ID" value="XM_003717190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7W5"/>
    <dbReference type="GeneID" id="2684499"/>
    <dbReference type="KEGG" id="mgr:MGG_06344"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06344"/>
    <dbReference type="eggNOG" id="ENOG502RQNC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_580134_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7W5"/>
    <dbReference type="OMA" id="KYIVSAN"/>
    <dbReference type="OrthoDB" id="4739136at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="471" mass="53633" checksum="0766F438FF0A2646" modified="2011-12-14" version="1">MNYRRPHPAADPDFDARNAEVEPDSRLQDGFIKMLLVLPNCMPDARDRDLIERKTELIQNPNLKAKLYMPESEKDSAFVSLGATSKLFMQQGITTAVEYFGRSHESLAMLEGPLLLVQIPAIGRENFLVREHPLKVDDHRRLEITALPPQQSEVWRYCLDSTTRASPEIFTPASHRIDSLEDVPLETTVVVFTPSLRFDMKLQGFAGRENSSKANMGLVRPSIFKRELRNREKYIVSANPGGAFDWDLEVLIRESQDNLDDRLRQLDRFMKVKTEPDGTYRPFFEDKLVQKAIGVTVISTKSARIYEMGLYQVELAVYIDWDPYTGKRLWQSCAMSLYSVDWNEVLERRNLALGPRDFGVCNSALLSVGPDDKLEDGAAILLETVEKLQKFLMDLVCESNVGMDIEQTTQAEPHDVEVATENEVLADTVTQHVQNVNIKASKSLKLINTKPETNAETKAKRPQPKKKSYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8F5</accession>
    <name>G4N8F5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Adenosine kinase</fullName>
            <shortName evidence="11">AK</shortName>
            <ecNumber evidence="4 11">2.7.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Adenosine 5'-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_06270</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine + ATP = AMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20824"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.20" evidence="4 11"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717322.1">
        <property type="nucleotide sequence ID" value="XM_003717274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8F5"/>
    <dbReference type="SMR" id="G4N8F5"/>
    <dbReference type="FunCoup" id="G4N8F5">
        <property type="interactions" value="1259"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N8F5"/>
    <dbReference type="GeneID" id="2684425"/>
    <dbReference type="KEGG" id="mgr:MGG_06270"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06270"/>
    <dbReference type="eggNOG" id="KOG2854">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045832_1_0_1"/>
    <dbReference type="InParanoid" id="G4N8F5"/>
    <dbReference type="OMA" id="RTMCTYL"/>
    <dbReference type="OrthoDB" id="432447at2759"/>
    <dbReference type="BRENDA" id="2.7.1.20">
        <property type="organism ID" value="5238"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00659"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004001">
        <property type="term" value="F:adenosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01168">
        <property type="entry name" value="adenosine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000014">
        <property type="entry name" value="ADO1p Adenosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001805">
        <property type="entry name" value="Adenokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769:SF3">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00989">
        <property type="entry name" value="ADENOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 11" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="12">
        <location>
            <begin position="28"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA51003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="361" mass="39459" checksum="8AF2344D30F36B51" modified="2011-12-14" version="1">MSSPKEFRLFCLENPLLDIQAVGDEALLNKYGLKANDAILAEAKHAGIFEELLNNYDAKLIPGGAAQNTARGAQYMLPPNSVVYSGGVGDDKYSAILRDAVQKVGLRVEYRVDPKETTGRCAVVITGHNRSMCTELGAANHYEVEFLKKPEVWELVKGAEVYYIGGYHFTVCPPAIMELAKEAATNNKTFILSLSAPFIPQFFKDPLDAALPYCDYVIGNETEAAAFAESHDMADKKDDVRAIAKAIANLPKENSQRKRVAIITQGTLPTIVAVQGEEEVKEYPVHEIAKEQINDTNGAGDAFAAGFCAGVVENKALAECVDRGQWLARLSIRSWVLHTPSPSRPTSPSLLNNLSWLLLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8M7</accession>
    <name>G4N8M7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_12707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716540.1">
        <property type="nucleotide sequence ID" value="XM_003716492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8M7"/>
    <dbReference type="SMR" id="G4N8M7"/>
    <dbReference type="STRING" id="242507.G4N8M7"/>
    <dbReference type="GeneID" id="5050084"/>
    <dbReference type="KEGG" id="mgr:MGG_12707"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12707"/>
    <dbReference type="eggNOG" id="KOG1515">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012494_3_1_1"/>
    <dbReference type="InParanoid" id="G4N8M7"/>
    <dbReference type="OMA" id="VIALHYW"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="100"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA50221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="418" mass="46993" checksum="9FDED94998F15E54" modified="2011-12-14" version="1">MSPKVRENGAQPRMDSKGDMNKITYVAPSMIERLVYCWYMWAMKGFSAPFIWYRDWMEWYYPPDGRPDIVKAYECRPHLPVRIFFPASYDRSSQTKLPALVAIHGGGFCFGTARDTDEWARAFADQHSTLVACPSYSKAPWSPFPAALNDIEAIYKAIVADESLPISKSQVAIAGWSAGGNLAMAVSQMPSIRALSPGAPSGAITIYGAMDMSVSAADKAKTRWYKTRLQHPRGQTEDGLFKLAPLCDWGYIPFGTDLRHPLLSPGFADERNLPPYVCVVAAELDMLAHESWRFAVRLDNERFPDRHRDVPDPNSDDPELAVAGRKAPSRRRGRLEEEDGGDDRFGWEDNGDGFGVKWMLVPDALHGFDCASIRLMTGGWDAVKDAEMKTKVEIERLGRWLRTKVWKLDEEKKSAESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8X1</accession>
    <name>G4N8X1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716584.1">
        <property type="nucleotide sequence ID" value="XM_003716536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8X1"/>
    <dbReference type="GeneID" id="12984514"/>
    <dbReference type="KEGG" id="mgr:MGG_17105"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17105"/>
    <dbReference type="HOGENOM" id="CLU_2671552_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8X1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="75" mass="7788" checksum="B41916EF4ECA1BCD" modified="2011-12-14" version="1">MSPPHVILPKNGTAHDATRPPAACKSSPEGGHGGHGRGYLTHTFVGEGSRNICPDEIKDTTLTDARVLGTLLNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N933</accession>
    <name>G4N933_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gelsolin repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10059</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717447.1">
        <property type="nucleotide sequence ID" value="XM_003717399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N933"/>
    <dbReference type="SMR" id="G4N933"/>
    <dbReference type="STRING" id="242507.G4N933"/>
    <dbReference type="GeneID" id="2681670"/>
    <dbReference type="KEGG" id="mgr:MGG_10059"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10059"/>
    <dbReference type="eggNOG" id="KOG0443">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002568_0_1_1"/>
    <dbReference type="InParanoid" id="G4N933"/>
    <dbReference type="OMA" id="HDMTLAK"/>
    <dbReference type="OrthoDB" id="6375767at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008154">
        <property type="term" value="P:actin polymerization or depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11290">
        <property type="entry name" value="gelsolin_S1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007122">
        <property type="entry name" value="Villin/Gelsolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977:SF130">
        <property type="entry name" value="SEVERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977">
        <property type="entry name" value="VILLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00262">
        <property type="entry name" value="GEL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gelsolin-like" evidence="2">
        <location>
            <begin position="70"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="2">
        <location>
            <begin position="208"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="426" mass="48387" checksum="EC4B9FC66E3070B6" modified="2011-12-14" version="1">MPPNKGLVHLKEYDIKDSNVELIGSALDHRVKYQSAQTEPAWNDGRVGIEPGLLVWRIERFEVVPWPRDRYGQFYDGDSYIVLHSWKVGKENQEGQQQAADSEQEQNKLGHEIFFWLGRYTSQDEAGTAAYKTVELDEFLRGRATQHRELQKCMSDEFVALFPRIKILSGGVESGFRRVEEDPEEKQDYVTLLRVFKLPGGKAGRDSIVVHEVDASAASLDDKDVFVLDTGSKIWVWQGRACSPMEKAKAAQVVHDMTLAKHVEVEVLSQTESRHSVVVSMLGGKDEYGPSHEFKCARPVGTRSGEDSSQSQQTQQRRRPRRLWRLSDASGRLEFTLVKDGEPLSPRDLDGNDVFLLDDEGREIWIWEGRGASKAEKASWLRVAQHYVRRTLEQEGGDEDDLYSTPIAKVKQGDETQGFMRALQAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9E6</accession>
    <name>G4N9E6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA51187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466315" evidence="1">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="80" mass="8769" checksum="1B24FDFECB654DA8" modified="2011-12-14" version="1">MQVSKIALAIAFYSLSVAAFPIRANCGPTTSRELQNGVTSGTEVAVKHGFKLQAREDKLFKCGKLLRSKYRVTCSYGKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9J4</accession>
    <name>G4N9J4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mRNA 3'-end-processing protein RNA14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_03265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Nucleus and/or cytoplasm.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA50386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716705.1">
        <property type="nucleotide sequence ID" value="XM_003716657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9J4"/>
    <dbReference type="SMR" id="G4N9J4"/>
    <dbReference type="FunCoup" id="G4N9J4">
        <property type="interactions" value="1176"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9J4"/>
    <dbReference type="GeneID" id="2676854"/>
    <dbReference type="KEGG" id="mgr:MGG_03265"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03265"/>
    <dbReference type="eggNOG" id="KOG1914">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007630_1_1_1"/>
    <dbReference type="InParanoid" id="G4N9J4"/>
    <dbReference type="OMA" id="VQLWSVY"/>
    <dbReference type="OrthoDB" id="26282at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180010">
        <property type="term" value="P:co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045243">
        <property type="entry name" value="Rna14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980:SF0">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980">
        <property type="entry name" value="RNA CLEAVAGE STIMULATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Suppressor of forked" evidence="6">
        <location>
            <begin position="166"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="818"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="918"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="131"/>
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        </location>
    </feature>
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    </feature>
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        </location>
    </feature>
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            <begin position="1013"/>
            <end position="1028"/>
        </location>
    </feature>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU369035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA50386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1057" mass="117578" checksum="CD7620062267066C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9T2</accession>
    <name>G4N9T2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715908.1">
        <property type="nucleotide sequence ID" value="XM_003715860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9T2"/>
    <dbReference type="GeneID" id="5049255"/>
    <dbReference type="KEGG" id="mgr:MGG_13934"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13934"/>
    <dbReference type="HOGENOM" id="CLU_642626_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9T2"/>
    <dbReference type="OrthoDB" id="5228416at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="427" mass="47990" checksum="BFB5FF721B056C64" modified="2011-12-14" version="1">MCSWTPEGRDVTANVDAHFYAHEVWAQLGECYLFIYLSLLSFYLFVYLTSHLVYKSTSNPVSPSILIALPVKHSHSLYFLNPNTLLDQKKALTTLYIQNPTEINRIIMSTETDAELGTALSECQIMERQAETAKRGSCRKLTLEDLPPEIMFIICEYVLFSNTQSAPRNPARDQHMRFQSPAARGVWLPRLLGIDGWEEQQTQTALLRTSRFLSGCARRVLATSKFRAQVDVDVMWVATSGMWPTVLSPTACYRSALDGSRPGTTVEVLTVSIRLFDDPAGLHWSLAGWGRFLPIPKGEVAIATAIQSLPPAMKQADRVVFCPPFVANGYYHRWGDFGNGESAWPKGWTVPDDLGPEEQRNRKRLLPWEGCKLRARTAMADKVANFLCSELLELMRRDEGLGELGEGLERVEFKVGGVLRRAVEVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9Y2</accession>
    <name>G4N9Y2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b-c1 complex subunit 2, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Core protein II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_03226</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716753.1">
        <property type="nucleotide sequence ID" value="XM_003716705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9Y2"/>
    <dbReference type="SMR" id="G4N9Y2"/>
    <dbReference type="FunCoup" id="G4N9Y2">
        <property type="interactions" value="282"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N9Y2"/>
    <dbReference type="GeneID" id="2676460"/>
    <dbReference type="KEGG" id="mgr:MGG_03226"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03226"/>
    <dbReference type="eggNOG" id="KOG2583">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_0_1_1"/>
    <dbReference type="InParanoid" id="G4N9Y2"/>
    <dbReference type="OMA" id="APKFALY"/>
    <dbReference type="OrthoDB" id="6369905at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000021">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000039">
        <property type="entry name" value="Ubiquinol-cytochrome c reductase core subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF209">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="12">
        <location>
            <begin position="54"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="13">
        <location>
            <begin position="210"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA50434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="463" mass="48229" checksum="0345AA48F332B383" modified="2011-12-14" version="1">MISRSAIKRGSQLALRRPVCAHVAQTRGFASPAPGATGTGSASYEPTSIAGLKVASKDAHGPTTKIALVVKAGTRYQPQPGLTVGLEEFAFKNTNKRSALRITRETELLGGQLKAYHTREAVVLEAAFLRDDLPYFVELLGEVANETRYTTHELHEEVEQTIHLAQEKLAHDSLAQAVDGAHAVAFHTGLGAPVLPSTSTPLSKYMNEHSVAAFAGAAYTKSNVALVADGASQSGLQQWVDSFFKDLPSQSSSEISLLSNKSTYHGGEHRAELPGKSSYVIAFPSASIAESKPEIAVIEALLGGNPSLSWSTGFTLLSKAAANAPGANAVAKNLSYSDAGLLTIQITGAAPAVRKLAEESVKALKAIAEGGVAQEDLTKAIAKAKFNALTAHELTGAGIVAAGTSIIHGAELFQAAQTIKNLETVTAEKIKTAAKAIIDGKASVSAVGDLHVLPFAADLGLKV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2016-05-11" modified="2025-02-05" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAP4</accession>
    <accession>A0A0M4MCV3</accession>
    <accession>Q52YI5</accession>
    <accession>Q52ZN7</accession>
    <name>MNLOX_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Manganese lipoxygenase</fullName>
            <shortName evidence="7">MnLOX</shortName>
            <ecNumber evidence="5">1.13.11.-</ecNumber>
            <ecNumber evidence="5">1.13.11.45</ecNumber>
            <ecNumber evidence="5">1.13.11.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Manganese 9S/11S-lipoxygenase</fullName>
            <shortName>9S/11S-MnLOX</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ORF">MGG_08499</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2015" name="Arch. Biochem. Biophys." volume="583" first="87" last="95">
            <title>Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of alpha-linolenic acid.</title>
            <authorList>
                <person name="Wennman A."/>
                <person name="Jerneren F."/>
                <person name="Magnuson A."/>
                <person name="Oliw E.H."/>
            </authorList>
            <dbReference type="PubMed" id="26264916"/>
            <dbReference type="DOI" id="10.1016/j.abb.2015.07.014"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [MRNA]</scope>
        <scope>REVISION OF GENE MODEL</scope>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <source>
            <strain>Guyane 11</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="journal article" date="2016" name="J. Biol. Chem." volume="291" first="8130" last="8139">
            <title>Crystal structure of manganese lipoxygenase of the rice blast fungus Magnaporthe oryzae.</title>
            <authorList>
                <person name="Wennman A."/>
                <person name="Oliw E.H."/>
                <person name="Karkehabadi S."/>
                <person name="Chen Y."/>
            </authorList>
            <dbReference type="PubMed" id="26783260"/>
            <dbReference type="DOI" id="10.1074/JBC.M115.707380"/>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (2.04 ANGSTROMS) OF 17-619 IN COMPLEX WITH MANGANESE</scope>
        <scope>GLYCOSYLATION AT ASN-86; ASN-164 AND ASN-549</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>MUTAGENESIS OF ARG-539 AND PHE-540</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Lipoxygenase that metabolizes linoleic and alpha-linolenic acids to 9S-, 11- and 13R-hydroperoxy fatty acids. At the end of lipoxygenation, the intermediate product 11S-HPODE from linoleic acid is then transformed into 9S-HPODE and 13R-HPODE as the final products. The intermediate product 11R-HPOTrE from alpha-linolenic acid is transformed into 9S-HPOTrE and 13R-HPOTrE as the final products. 9S-HPOTrE is further oxidized by the enzyme to 9S,16S-DiHPOTrE as the end product.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(9Z,12Z)-octadecadienoate + O2 = (9S)-hydroperoxy-(10E,12Z)-octadecadienoate</text>
            <dbReference type="Rhea" id="RHEA:30291"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30245"/>
            <dbReference type="ChEBI" id="CHEBI:60955"/>
            <dbReference type="EC" id="1.13.11.58"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(9Z,12Z)-octadecadienoate + O2 = (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate</text>
            <dbReference type="Rhea" id="RHEA:18993"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30245"/>
            <dbReference type="ChEBI" id="CHEBI:57467"/>
            <dbReference type="EC" id="1.13.11.45"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(9Z,12Z)-octadecadienoate + O2 = (13R)-hydroperoxy-(9Z,11E)-octadecadienoate</text>
            <dbReference type="Rhea" id="RHEA:51240"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30245"/>
            <dbReference type="ChEBI" id="CHEBI:133985"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(9Z,12Z,15Z)-octadecatrienoate + O2 = (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate</text>
            <dbReference type="Rhea" id="RHEA:51248"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:32387"/>
            <dbReference type="ChEBI" id="CHEBI:60962"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(9Z,12Z,15Z)-octadecatrienoate + O2 = (11R)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate</text>
            <dbReference type="Rhea" id="RHEA:51252"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:32387"/>
            <dbReference type="ChEBI" id="CHEBI:133989"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(9Z,12Z,15Z)-octadecatrienoate + O2 = (13R)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate</text>
            <dbReference type="Rhea" id="RHEA:51244"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:32387"/>
            <dbReference type="ChEBI" id="CHEBI:133987"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate + O2 = (9S,16S)-dihydroperoxy-(10E,12Z,14E)-octadecatrienoate</text>
            <dbReference type="Rhea" id="RHEA:51256"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:60962"/>
            <dbReference type="ChEBI" id="CHEBI:133991"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Three His residues, the carboxyl oxygen of the C-terminal Ile or Val residue, and a fifth residue, usually Asn, ligate the metal, which binds water to form a catalytic base Mn(2+)OH(2) for hydrogen abstraction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the lipoxygenase family. Manganese lipoxygenase subfamily.</text>
    </comment>
    <comment type="sequence caution" evidence="8">
        <conflict type="erroneous gene model prediction">
            <sequence resource="EMBL-CDS" id="EHA49687" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="1.13.11.-" evidence="5"/>
    <dbReference type="EC" id="1.13.11.45" evidence="5"/>
    <dbReference type="EC" id="1.13.11.58" evidence="5"/>
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    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBN7</accession>
    <name>G4NBN7_PYRO7</name>
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        <recommendedName>
            <fullName evidence="8">Lipase</fullName>
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        <name evidence="6" type="ORF">MGG_14244</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717726.1">
        <property type="nucleotide sequence ID" value="XM_003717678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBN7"/>
    <dbReference type="SMR" id="G4NBN7"/>
    <dbReference type="FunCoup" id="G4NBN7">
        <property type="interactions" value="7"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NBN7"/>
    <dbReference type="GeneID" id="5048803"/>
    <dbReference type="KEGG" id="mgr:MGG_14244"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14244"/>
    <dbReference type="eggNOG" id="KOG4569">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032957_1_0_1"/>
    <dbReference type="InParanoid" id="G4NBN7"/>
    <dbReference type="OMA" id="YTAAAYC"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051299">
        <property type="entry name" value="AB_hydrolase_lip/est"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005592">
        <property type="entry name" value="Mono/diacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640:SF1">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46640">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G06510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03893">
        <property type="entry name" value="Lipase3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466804" description="Lipase" evidence="3">
        <location>
            <begin position="22"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Mono-/di-acylglycerol lipase N-terminal" evidence="5">
        <location>
            <begin position="27"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="4">
        <location>
            <begin position="104"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA48142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="32461" checksum="1E71DA14B5C5B7F0" modified="2011-12-14" version="1">MWTTRLLSLLLLSLASKGCLGQSSAAIRGSVTQAELDTFKLYADYTAAAYCNKSPDRVSQKIVCGSDACPLIEAHETTIVATLADDGDRAGGYVALDSTAERIVVAFHGTITFAGYMADFNALLQDDDLCQGCQIHAGFRSIWAAVGDVVMETVEKLHSEYPDYSIVTTGHSMGAALATLAGANLRQKIPEKVIDVYSLGSPRVGNQAFAEYVSAQPGSVFRITHVNDPVPRLPPNLMGYYHTDVEYWLSTGGALTTDYTPNDVLVCKGIFNRNCNTKSDFFGFGFAAHVNYLTRIGACKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC56</accession>
    <name>G4NC56_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_11422</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717789.1">
        <property type="nucleotide sequence ID" value="XM_003717741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC56"/>
    <dbReference type="GeneID" id="5050587"/>
    <dbReference type="KEGG" id="mgr:MGG_11422"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11422"/>
    <dbReference type="eggNOG" id="KOG1014">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1603067_0_0_1"/>
    <dbReference type="InParanoid" id="G4NC56"/>
    <dbReference type="OMA" id="PRFNCFA"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051019">
        <property type="entry name" value="VLCFA-Steroid_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899:SF13">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA48205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="166" mass="17667" checksum="8512F9302A14341C" modified="2011-12-14" version="1">MSSLLSSPSSVDEQGNTKRPWTPVTGASDGISRQLAAELATHGFDIVVHGRNNAKLATVEGELRREFPAREFRSLAADLGKMPRFNCFAAAAPPSGGAVDLDSIVVQLRGLQLTVVVNTPSALNRRQSGCGRGVVVPYLLHGLPAAIVELLSEFVRANIPVKVTRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCB9</accession>
    <name>G4NCB9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_00421</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718652.1">
        <property type="nucleotide sequence ID" value="XM_003718604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCB9"/>
    <dbReference type="SMR" id="G4NCB9"/>
    <dbReference type="STRING" id="242507.G4NCB9"/>
    <dbReference type="GeneID" id="2674941"/>
    <dbReference type="KEGG" id="mgr:MGG_00421"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00421"/>
    <dbReference type="eggNOG" id="ENOG502R9YC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044876_3_2_1"/>
    <dbReference type="InParanoid" id="G4NCB9"/>
    <dbReference type="OMA" id="LDFQNHT"/>
    <dbReference type="OrthoDB" id="9974981at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF1">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="11"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA49068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="322" mass="35139" checksum="8C04420DFB62F402" modified="2011-12-14" version="1">MPGRFSISKVVLVGKGYVGGYVYAALVDAGFQVTVLSRSNPKGDHHVKIVDYSSTESIRRAIQDHDAVVCTISHTAWEHQYRLIDAAVEAGTVKHFIPSDFTALSCNAAVHHLPYYREAAAMQNYLAQKADGAGMRWNVIQSGPIIGCVLNGSYSYDFRERTALLVGDRSIREHEVSMSRGVTVGRAVAAILGRGGDSKNGPVYIGDVVTTQGEILRLAEEKSGAEWAVREVDPEAKLKEALSMSEVAAAEGKPTPMFATFLVIHNTIFGAKYRTAWDGRDIEELGIPTLTREEWGRMVATRVCNEPVDGGLPWNSSSKPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCD8</accession>
    <name>G4NCD8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718671.1">
        <property type="nucleotide sequence ID" value="XM_003718623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCD8"/>
    <dbReference type="STRING" id="242507.G4NCD8"/>
    <dbReference type="GeneID" id="5050740"/>
    <dbReference type="KEGG" id="mgr:MGG_11584"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11584"/>
    <dbReference type="eggNOG" id="KOG4626">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001305_5_2_1"/>
    <dbReference type="InParanoid" id="G4NCD8"/>
    <dbReference type="OMA" id="VINMSAH"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="267"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="529" mass="58102" checksum="EE8840F0F9C126CE" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND52</accession>
    <name>G4ND52_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717978.1">
        <property type="nucleotide sequence ID" value="XM_003717930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND52"/>
    <dbReference type="SMR" id="G4ND52"/>
    <dbReference type="STRING" id="242507.G4ND52"/>
    <dbReference type="GeneID" id="2675141"/>
    <dbReference type="KEGG" id="mgr:MGG_00972"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00972"/>
    <dbReference type="eggNOG" id="ENOG502SCE7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070839_1_0_1"/>
    <dbReference type="InParanoid" id="G4ND52"/>
    <dbReference type="OMA" id="WQRRDIE"/>
    <dbReference type="OrthoDB" id="5279705at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="232" mass="26507" checksum="2A40F64C439B5C60" modified="2011-12-14" version="1">MFAVMPSYPVFNDFSYQPTRSSPLSSSSPIRASSPPPAPLSPCDYNRQPRQVQSSPVQAPPSKFKFSARPARPNPVVRNREATQQSRRNLFLKGVQQRADDHRWERRGVEHKVLSTEWFNETQARQQAKLLDPDSLLTEEDIEDAERLEEERQSRYEEIPDDLMMDSMMEDEHEFEALASNVQQQQAPSSGTTRPDSPHLLDDEDYDSLFMDFLSTQNQQTAPASSGDVEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDX5</accession>
    <name>G4NDX5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718941.1">
        <property type="nucleotide sequence ID" value="XM_003718893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDX5"/>
    <dbReference type="SMR" id="G4NDX5"/>
    <dbReference type="FunCoup" id="G4NDX5">
        <property type="interactions" value="73"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NDX5"/>
    <dbReference type="GeneID" id="2674655"/>
    <dbReference type="KEGG" id="mgr:MGG_00180"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00180"/>
    <dbReference type="eggNOG" id="KOG0417">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_13_0_1"/>
    <dbReference type="InParanoid" id="G4NDX5"/>
    <dbReference type="OMA" id="WRAVMKG"/>
    <dbReference type="OrthoDB" id="9973183at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd23812">
        <property type="entry name" value="UBCc_ScPEX4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="8"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="166" mass="18003" checksum="CB30A1C9DB8FAAFA" modified="2011-12-14" version="1">MAPKSDRSATRRLIKELETWHGESKSETGVERLGPVNEGELLQWEAVINGKGIGGGYDAGRWLLEIKIPPTYPLHPPTVRFVTPVVHANVNLADGEVCLDLLKEAWTPAYSVLETVRAVRLLLATPEPDSPLNVDVAALVRAGDALGAARLVEFWITDGGGRYDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE59</accession>
    <name>G4NE59_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="17">DNA-repair protein rad13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_00155</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of excision-repair.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718972.1">
        <property type="nucleotide sequence ID" value="XM_003718924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE59"/>
    <dbReference type="SMR" id="G4NE59"/>
    <dbReference type="FunCoup" id="G4NE59">
        <property type="interactions" value="523"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NE59"/>
    <dbReference type="GeneID" id="2674291"/>
    <dbReference type="KEGG" id="mgr:MGG_00155"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00155"/>
    <dbReference type="eggNOG" id="KOG2520">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003018_0_0_1"/>
    <dbReference type="InParanoid" id="G4NE59"/>
    <dbReference type="OMA" id="PNSMDFS"/>
    <dbReference type="OrthoDB" id="31113at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048256">
        <property type="term" value="F:flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd09904">
        <property type="entry name" value="H3TH_XPG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09868">
        <property type="entry name" value="PIN_XPG_RAD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000025">
        <property type="entry name" value="DNA repair protein RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000030">
        <property type="entry name" value="Flap endonuclease GEN-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000061">
        <property type="entry name" value="Single-stranded DNA endonuclease (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001044">
        <property type="entry name" value="XPG/Rad2_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171:SF7">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00066">
        <property type="entry name" value="XRODRMPGMNTG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00842">
        <property type="entry name" value="XPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="16">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="15">
        <location>
            <begin position="922"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="350"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="508"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="622"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="694"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1154"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="549"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="697"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="748"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1154"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1229"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1256"/>
            <end position="1269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00053135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA49388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1269" mass="140332" checksum="A616D5C1F049881A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFH2</accession>
    <name>G4NFH2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_17557</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719146.1">
        <property type="nucleotide sequence ID" value="XM_003719098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFH2"/>
    <dbReference type="STRING" id="242507.G4NFH2"/>
    <dbReference type="GeneID" id="12985194"/>
    <dbReference type="KEGG" id="mgr:MGG_17557"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17557"/>
    <dbReference type="eggNOG" id="ENOG502SYQN">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1518387_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFH2"/>
    <dbReference type="OMA" id="CQSMSHE"/>
    <dbReference type="OrthoDB" id="4589078at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="210" mass="23506" checksum="5E088B6925EFDABE" modified="2011-12-14" version="1">MGHLREEYKDTKLEDTARDELDKLIMSTKDKFMIFKNKFVKLAGQSGLPKRSWKRELHRRLPTNLRVAMVIYHQDTNVSFDAYVRTADGISYDLTKAYASRTEDKNKTKTTSIKKTTGGSVIPRAGGPARTTGGAVDEGQKGKLSVEEMRGLIRTGKCFQCREPGHISRNCPNGDTGRPTISEDRVNQIIASYHGKGTDMFGEDVVMSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFK2</accession>
    <name>G4NFK2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719176.1">
        <property type="nucleotide sequence ID" value="XM_003719128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFK2"/>
    <dbReference type="GeneID" id="2678962"/>
    <dbReference type="KEGG" id="mgr:MGG_08796"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08796"/>
    <dbReference type="eggNOG" id="ENOG502T43X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152689_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFK2"/>
    <dbReference type="OMA" id="ERASCTW"/>
    <dbReference type="OrthoDB" id="5186115at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466900" evidence="1">
        <location>
            <begin position="21"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="102" mass="11017" checksum="55B47B43A4371483" modified="2011-12-14" version="1">MKTTFTLLLIAMQAVSLAAAGPTDLPLGVEVREEQGSLVVREVSSEGTGLEKRCRECVHVGDRCTIGHGSCYAREQASCTWCGNHCKSICIPNGESCQKWCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFN3</accession>
    <name>G4NFN3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Quinate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_14136</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719207.1">
        <property type="nucleotide sequence ID" value="XM_003719159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFN3"/>
    <dbReference type="SMR" id="G4NFN3"/>
    <dbReference type="STRING" id="242507.G4NFN3"/>
    <dbReference type="GeneID" id="2678921"/>
    <dbReference type="KEGG" id="mgr:MGG_14136"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="MFS_dom"/>
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        <property type="entry name" value="MFS_sugar_transport-like"/>
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    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
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    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
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    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF8">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
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    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="28"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="526"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="526"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA46840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="553" mass="60761" checksum="2CA148860220D912" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGB4</accession>
    <name>G4NGB4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17624</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA47071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003719390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGB4"/>
    <dbReference type="GeneID" id="12985912"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_17624"/>
    <dbReference type="HOGENOM" id="CLU_1993066_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGB4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="125" mass="13999" checksum="EEA54F3A6B873F02" modified="2011-12-14" version="1">MVEYQVWLLAARSLVEIKLVYSGSGRSGHGKHFRAAIDKMTENSERTHSVAQNAARTGCGGWNKYSSDFVLPRMYGYLSTYFGFANIYDKPTWPSTDDGCSPYRTATTSWDASSRPAIGNDQQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGW5</accession>
    <name>G4NGW5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL4m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_04008</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719842.1">
        <property type="nucleotide sequence ID" value="XM_003719794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGW5"/>
    <dbReference type="SMR" id="G4NGW5"/>
    <dbReference type="FunCoup" id="G4NGW5">
        <property type="interactions" value="287"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGW5"/>
    <dbReference type="GeneID" id="2677278"/>
    <dbReference type="KEGG" id="mgr:MGG_04008"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04008"/>
    <dbReference type="eggNOG" id="KOG1624">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041575_4_0_1"/>
    <dbReference type="InParanoid" id="G4NGW5"/>
    <dbReference type="OMA" id="KTFGPHP"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000016">
        <property type="entry name" value="60S ribosomal protein L4, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF6">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA47475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="342" mass="37902" checksum="F6093E830FABD86F" modified="2011-12-14" version="1">MAGKGVRCLSEAMRTMRISSTLLPARQPMNWTKPLASSLSSRTMATTSDPTPFKTKLLNGGTEQSSAAPTQPIWTPPSEIPVTIYDFPSLEPLTLEAWPTKHLDLPFRRDLLHLAVTYEGDGTRQGTASSKTKWDVHGSHRKQAPQKGTGNARVGWKQSPLRRGGGKSHGPHPRDFSTRMNHKVYDLAWRTALSYRYRRGELFVVRDGSLDMPLPADFLALAAEGRLGRELEDGFVDRMVRETLNPLGWGKEGGRSTFVVSCDKAGRPNLFSSLEIAQKEARALEVDDVDVKDILETGRIVIERRALKRLIEEHQSDLVSRIVVNGSRVTGPLAGATRTLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHA0</accession>
    <name>G4NHA0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03899</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719977.1">
        <property type="nucleotide sequence ID" value="XM_003719929.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NHA0"/>
    <dbReference type="GeneID" id="2677193"/>
    <dbReference type="KEGG" id="mgr:MGG_03899"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03899"/>
    <dbReference type="eggNOG" id="ENOG502QRT9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006238_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHA0"/>
    <dbReference type="OMA" id="QGIQPQG"/>
    <dbReference type="OrthoDB" id="3366990at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010833">
        <property type="term" value="P:telomere maintenance via telomere lengthening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000137">
        <property type="entry name" value="MYB DNA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013867">
        <property type="entry name" value="Telomere_rpt-bd_fac_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052833">
        <property type="entry name" value="Telomeric_DNA-bd_trans-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47807">
        <property type="entry name" value="PROTEIN TBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47807:SF1">
        <property type="entry name" value="PROTEIN TBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08558">
        <property type="entry name" value="TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="786"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="68"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="735"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="769"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="896"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1005"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="170"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="735"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="772"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1007"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1045"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1080"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1101"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1147"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1199"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1234"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1254"/>
            <end position="1285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA47610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1308" mass="138816" checksum="69B5A62E7DEDBF31" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHC3</accession>
    <name>G4NHC3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Actin-related protein 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Actin-like protein 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_03879</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720000.1">
        <property type="nucleotide sequence ID" value="XM_003719952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHC3"/>
    <dbReference type="SMR" id="G4NHC3"/>
    <dbReference type="FunCoup" id="G4NHC3">
        <property type="interactions" value="728"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NHC3"/>
    <dbReference type="GeneID" id="2677366"/>
    <dbReference type="KEGG" id="mgr:MGG_03879"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03879"/>
    <dbReference type="eggNOG" id="KOG0678">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027965_3_0_1"/>
    <dbReference type="InParanoid" id="G4NHC3"/>
    <dbReference type="OMA" id="GIHYPIR"/>
    <dbReference type="OrthoDB" id="421448at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051285">
        <property type="term" value="C:cell cortex of cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd10221">
        <property type="entry name" value="ASKHA_NBD_Arp3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000029">
        <property type="entry name" value="Actin-related protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000006">
        <property type="entry name" value="Actin-related protein 3 (ARP3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="40"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA47633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="438" mass="47681" checksum="4B7FC00A465FD14F" modified="2011-12-14" version="1">MANQTPAVVMDNGTGFSKLGFAGNDSPSFVFPTAIATKSAGASGGTGSGRPAVANKPSFLTGGAGPGGHLSGKRGTEDLDFFIGDEAIAASSGPGYGLHYPIRHGQIENWDHMERFWSNSIFKYLRVEPEDHFFLLTEPPLNPPENRENTAEIFFESFNCAGLYIAVQAVLALAASWTSSKVHDRSLTGTVIDSGDGVTHVIPVAEGYVIGSSIKSIPIAGRDITYFVQSLLRDRGEPDSSLKTAQEIKEEYCYVCPDIVKEFTKFDRDRSRFARHVVSQPGGREVGVDVGYERFLAPEIFFNPEIYSSDFLTPLPVVVDGVIQSSPIDVRRGLYKNIVLSGGSTLYKDFGRRLQRDIKQLVDARIRASEMRSGGAKSGGLEVQVITHKRQRHGPWFGGSLLGQTPEFRSYCHTKAEYQEYGPGIVRRFALLGGPGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHJ0</accession>
    <name>G4NHJ0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Isotrichodermin C-15 hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_03825</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720067.1">
        <property type="nucleotide sequence ID" value="XM_003720019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHJ0"/>
    <dbReference type="STRING" id="242507.G4NHJ0"/>
    <dbReference type="GeneID" id="2677216"/>
    <dbReference type="KEGG" id="mgr:MGG_03825"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03825"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="InParanoid" id="G4NHJ0"/>
    <dbReference type="OMA" id="DYHPWIA"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA47700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="538" mass="60966" checksum="D34E3C345BF80319" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHJ4</accession>
    <name>G4NHJ4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase family T4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S58 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720071.1">
        <property type="nucleotide sequence ID" value="XM_003720023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHJ4"/>
    <dbReference type="SMR" id="G4NHJ4"/>
    <dbReference type="STRING" id="242507.G4NHJ4"/>
    <dbReference type="MEROPS" id="P01.003"/>
    <dbReference type="GeneID" id="2677213"/>
    <dbReference type="KEGG" id="mgr:MGG_03822"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03822"/>
    <dbReference type="eggNOG" id="ENOG502QRNQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024709_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHJ4"/>
    <dbReference type="OMA" id="CNDGWLN"/>
    <dbReference type="OrthoDB" id="2107894at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02253">
        <property type="entry name" value="DmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.70.12:FF:000004">
        <property type="entry name" value="Beta-peptidyl aminopeptidase BapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.70.12">
        <property type="entry name" value="L-amino peptidase D-ALA esterase/amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005321">
        <property type="entry name" value="Peptidase_S58_DmpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36512:SF3">
        <property type="entry name" value="BLR5678 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36512">
        <property type="entry name" value="D-AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03576">
        <property type="entry name" value="Peptidase_S58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="DmpA/ArgJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="395" mass="42006" checksum="3FF70CB1011BFCEC" modified="2011-12-14" version="1">MTTPASSKKPRCRVREAVPGIHLGFWPPGPRNSLTDVPGVLVHTETIRSADGQVNTGATTILPRKDWFRDACHAGVFRFNGAGEMTGCHWLEETGLLASPIVITNSFSVGDAYRGVLDYAVEHNRAHGTKWFMLPVVAETFDGFMNDLYRFAVKPEHIAQSIRSASSAPVPEGNVGGGTGMLCQGFKGGTGSSSRLVPGVKLSAAAGDGKTKETSWTVAALVQANYGQLHHLHFAGVPVGRIMAEQRRADEATAAADRAYAEAKDDKDGSIIVVVATDAPLNPLQCQRLARRATAGLARVGGYGHNLSGDIFLAFSTGSSVVVQTEGGQPAQEIAGSSIDDNTINALFEAAADATQEAIYNALCMAETMTGFEGHTVEAIDLDKLREIMDKHMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHL3</accession>
    <name>G4NHL3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03806</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720090.1">
        <property type="nucleotide sequence ID" value="XM_003720042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHL3"/>
    <dbReference type="SMR" id="G4NHL3"/>
    <dbReference type="STRING" id="242507.G4NHL3"/>
    <dbReference type="GeneID" id="2677136"/>
    <dbReference type="KEGG" id="mgr:MGG_03806"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03806"/>
    <dbReference type="HOGENOM" id="CLU_1949247_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHL3"/>
    <dbReference type="OrthoDB" id="444540at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466961" description="EF-hand domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="161" mass="17052" checksum="8B719D6222F245A8" modified="2011-12-14" version="1">MKFATAAVLILTAVPAALACCKQKGITSCCGKGKCNIFCCNCDGGCRDNCGANLPICWATGGANVICARSPGAEEMSSIPSKLDMVEGTLGSSVAGLSAEERRAEDVKVFNQVDLDGKGFFTYGEFLDFSGEPDSEELKEYFAKYDKNGDGGITVEEMRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHU6</accession>
    <name>G4NHU6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_09431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720173.1">
        <property type="nucleotide sequence ID" value="XM_003720125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHU6"/>
    <dbReference type="GeneID" id="2680387"/>
    <dbReference type="KEGG" id="mgr:MGG_09431"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09431"/>
    <dbReference type="HOGENOM" id="CLU_578801_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHU6"/>
    <dbReference type="OrthoDB" id="4924398at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="472" mass="51654" checksum="603DD5709BFC1362" modified="2011-12-14" version="1">MSNIQQEDTKPTVAAGEGAAATAYMSRLLSMALQVANFSNTNRPWRLYDLSHPINNPELMSLCQLQRLHPRETLMVHPIKWKNIHLDILRCVFYPDDSPLQAFAPDYAITNEAMSCACHLQALLSPVSTRRDKMAAVTALFTGLTDSSSEVGFTSDLHLAYDHVHSPLPLAFASTMGMLTIPDGGYKAVSDGELPHACVLGHLAKGTHTHLANLAYVDLGSVMAKRRQWRLKHIARTWADQARDPFIVATIIGLAQRVDRESGRLPVREANGRVYEDLHDARTWSLASIMLAEGEGDEKSDREVAQALLQARFVCLLYQVARARSLTVVPGPAGGFLPQVREPTTEAEVMAGVVNCARYVVAGGHVGEDMLRGLDALKAVMRLGRAGPVGRYRCVCLASSPTDGDNFLVYSAAVSTAFLDRLEKPHEPPRVDVQSGLEIRVGLFPLRPLETLPSRLEVLLRLLGSPVDAESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NID2</accession>
    <name>G4NID2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAS1 domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720359.1">
        <property type="nucleotide sequence ID" value="XM_003720311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NID2"/>
    <dbReference type="GeneID" id="2680832"/>
    <dbReference type="KEGG" id="mgr:MGG_09875"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09875"/>
    <dbReference type="eggNOG" id="ENOG502QUBE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047729_3_2_1"/>
    <dbReference type="InParanoid" id="G4NID2"/>
    <dbReference type="OMA" id="GMQCTGT"/>
    <dbReference type="OrthoDB" id="5418436at2759"/>
    <dbReference type="PHI-base" id="PHI:123067"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021476">
        <property type="entry name" value="Egh16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618:SF4">
        <property type="entry name" value="CAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34618">
        <property type="entry name" value="SURFACE PROTEIN MAS1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11327">
        <property type="entry name" value="Egh16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466378" evidence="1">
        <location>
            <begin position="23"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="275" mass="27591" checksum="817965B73E828793" modified="2011-12-14" version="1">MFAKVTILSVLLAGAELVSGHAAIINAVGDAGGVGMALGVDTATPRDGTRRNPFQQDATRFRGASSATVGETLGGGTNNIQAGTQAIMAETGSELPQVSAGGQLEMTLHQVNADGAGPYTCKINSDGTAAQWTPIQVATQVPGRNSRDRNGAQTDHPLVASIPAGQTCTGTVAGQENVCLVRCENGARAGPFGGVIPIQIGAGAGAGAGAGAGAGAGAAGNGTAPAAGAAAERRNAQALARRALARDIVRREALLRKVMKRAMIETEEDIEDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIQ4</accession>
    <name>G4NIQ4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP phosphoribosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719677.1">
        <property type="nucleotide sequence ID" value="XM_003719629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIQ4"/>
    <dbReference type="SMR" id="G4NIQ4"/>
    <dbReference type="STRING" id="242507.G4NIQ4"/>
    <dbReference type="GeneID" id="12986146"/>
    <dbReference type="KEGG" id="mgr:MGG_17680"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17680"/>
    <dbReference type="eggNOG" id="ENOG502S6WE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_120084_2_1_1"/>
    <dbReference type="InParanoid" id="G4NIQ4"/>
    <dbReference type="OMA" id="NYTECCF"/>
    <dbReference type="OrthoDB" id="15981at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41774">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41774:SF1">
        <property type="entry name" value="NGG1P INTERACTING FACTOR NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="116" mass="12525" checksum="F11FFD835097C62E" modified="2011-12-14" version="1">MAAAVAATARYKLVFFTPPAALTQCKTAVFAAGAGRFPGPGNYTECCWTVMGTGQFRPGDTANPNMGSVGQLEQIEEARVEVLCVGESVARKAVEELKKAHPFEEPAYEVYKMEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIV1</accession>
    <name>G4NIV1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SET domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719724.1">
        <property type="nucleotide sequence ID" value="XM_003719676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIV1"/>
    <dbReference type="SMR" id="G4NIV1"/>
    <dbReference type="STRING" id="242507.G4NIV1"/>
    <dbReference type="GeneID" id="2677617"/>
    <dbReference type="KEGG" id="mgr:MGG_04107"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04107"/>
    <dbReference type="eggNOG" id="KOG1337">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044629_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIV1"/>
    <dbReference type="OMA" id="AWYRSRC"/>
    <dbReference type="OrthoDB" id="441812at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF76">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="23"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="478" mass="53045" checksum="EB830BECE1B7C603" modified="2011-12-14" version="1">MSQSDVPIDTLLIWARFNGVVFDGAAITQTEGKGYGLVAQRDLQAKDGEDTTVLLSVPRELLLNSEYVEQCSKTDQRFRDLFDAAGHQSPRQDVILFLMAQIIHIWASDEGGGVSNPWTQYIKYLPRTVPLPTLWNEDERQLLRGTSLEAAVHSKLRALENEFDNLLEKAAEIPSWNEVLCEKQVVTVSDYARLDAWYRSRCMELPASGPTMVPCIDMVNHAAIPNASYVKSSDCGVNLCLRSGAVVKSGQEITISYGEKKSAAEMLFSYGFVDSEAAGDEKILVPVEPPGDDPLVMAKTRIYGEAPTVRISRCQDGGVQWECPFAYLLSLNEEDGLGIRLLQLNDGCREIRLFWEEQDVTGSVKSLQDVTKEHPRSKIFQLRTVVIVQETVHAQVERLSTGTGDHGTTTGVRPSCRSAALNLRETEERLLRDAADVLETEKTKLLENETILAYLGRAEISQNDLADSGPANEETDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJD1</accession>
    <name>G4NJD1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Amine oxidase</fullName>
            <ecNumber evidence="14">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_15019</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16153"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:228804"/>
            <dbReference type="EC" id="1.4.3.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="14">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="14">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="13">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="13 14">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="14"/>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721090.1">
        <property type="nucleotide sequence ID" value="XM_003721042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJD1"/>
    <dbReference type="SMR" id="G4NJD1"/>
    <dbReference type="STRING" id="242507.G4NJD1"/>
    <dbReference type="GeneID" id="12984886"/>
    <dbReference type="KEGG" id="mgr:MGG_15019"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15019"/>
    <dbReference type="eggNOG" id="KOG1186">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011500_3_2_1"/>
    <dbReference type="InParanoid" id="G4NJD1"/>
    <dbReference type="OMA" id="CMHPSET"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="PHI-base" id="PHI:2171"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000006">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.40:FF:000014">
        <property type="entry name" value="Peroxisomal primary amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF86">
        <property type="entry name" value="COPPER AMINE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 14" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="16">
        <location>
            <begin position="32"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="17">
        <location>
            <begin position="123"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="15">
        <location>
            <begin position="250"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="12">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="13">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA46347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="704" mass="78400" checksum="8E0E405F1FE5F2F6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJT8</accession>
    <name>G4NJT8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="G4NJT8"/>
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    <dbReference type="KEGG" id="mgr:MGG_02590"/>
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        <property type="entry name" value="Cyanovirin-N_sf"/>
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        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466354" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="21"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="125" mass="13045" checksum="228683325D9E65BD" modified="2011-12-14" version="1">MKLSILATILLASSGVNAANGFASSCSNVALSGLILRGRCDEPGRFGVTPRQDTKLDVSKCFSLDGEGKISCKKGDIGACKCQLATNKSMTCNCNNSKGAKVQSDVDLGEYSHPARLPIEAGFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKP0</accession>
    <name>G4NKP0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721372.1">
        <property type="nucleotide sequence ID" value="XM_003721324.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NKP0"/>
    <dbReference type="GeneID" id="2682192"/>
    <dbReference type="KEGG" id="mgr:MGG_10579"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10579"/>
    <dbReference type="eggNOG" id="ENOG502S0A5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002906_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKP0"/>
    <dbReference type="OMA" id="NIGQDHV"/>
    <dbReference type="OrthoDB" id="1926336at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF80">
        <property type="entry name" value="GRIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="3">
        <location>
            <begin position="1250"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="944"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1182"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1218"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="651"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="274"/>
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        </location>
    </feature>
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        <location>
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            <end position="475"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="593"/>
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        </location>
    </feature>
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        <location>
            <begin position="606"/>
            <end position="615"/>
        </location>
    </feature>
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        <location>
            <begin position="1232"/>
            <end position="1252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1307" mass="145808" checksum="EB89ACA7101B2300" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKR5</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">MGG_17879</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720636.1">
        <property type="nucleotide sequence ID" value="XM_003720588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKR5"/>
    <dbReference type="GeneID" id="12984743"/>
    <dbReference type="KEGG" id="mgr:MGG_17879"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17879"/>
    <dbReference type="HOGENOM" id="CLU_2306672_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKR5"/>
    <dbReference type="OrthoDB" id="10614791at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA45893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="100" mass="10873" checksum="E79DC437E2827D02" modified="2011-12-14" version="1">MAARNSPLLSGVCRPVLSEMPRRPRFDARVWKRRQQPVSKTRQRSPGPSLPVCFDAVTDSLTLRTPSGSALWDATAIRSLPFCAGEASFSDGAGLVFLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL25</accession>
    <name>G4NL25_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_02991</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720701.1">
        <property type="nucleotide sequence ID" value="XM_003720653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL25"/>
    <dbReference type="GeneID" id="2682544"/>
    <dbReference type="KEGG" id="mgr:MGG_02991"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02991"/>
    <dbReference type="eggNOG" id="ENOG502RAWG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018003_1_1_1"/>
    <dbReference type="InParanoid" id="G4NL25"/>
    <dbReference type="OMA" id="SNCTGHN"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="3">
        <location>
            <begin position="35"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA45958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="438" mass="48773" checksum="1EDA9ACEA7B62969" modified="2011-12-14" version="1">MEQDTDTVRQYIEEQAIKFRTFTGIQRPPPNAVFILVMGMTGSGKSSFVASCTGKRVTVGHGLQSCTFDIDIFDFEFEGRQIFLIDTPGFNDTNKSDAETLATVSAYLGTSYAQNVFIHGILYLHRISDNRVSGSAKRNFGMFKALCGEASYGNVSLVTTMWTDAGREDQLRREAELRRDPNFFGSIIAGGASLLRHGERGTDLQQLRDSALSIVRQLIVQCRPGPVVLLIQHELVEEKKVLDDTSAGIIVQSDLHRAFADYRKELSNLRQEMNRTAQSRKSFASGEAQEMAELKAEFRQKLGAVERERNVLASDLARLQQREKETLLSKLEATEQRFQSELERQEGHLRELQRSLQKAEEDSTGDNTVQQTVTRSKLQKEVVNAGKKVVRERQKVRRLKTTVDGVKEGILDGFSTSLSSAIVAGVGTAVVALACVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHA4</accession>
    <name>G5EHA4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g290</name>
        <name evidence="2" type="ORF">MGG_15033</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721224.1">
        <property type="nucleotide sequence ID" value="XM_003721176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHA4"/>
    <dbReference type="GeneID" id="12985786"/>
    <dbReference type="KEGG" id="mgr:MGG_15033"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15033"/>
    <dbReference type="HOGENOM" id="CLU_1396599_0_0_1"/>
    <dbReference type="OrthoDB" id="2157530at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ70883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="195" mass="21655" checksum="4BD700F1E8860F42" modified="2011-12-14" version="1">MIRLEESRISGGDGMEPPVKALSELRDEFPFQDARQQDYSLPLEHIFTQFTQTVTRRHKSLAVLRIVENSSGQRLDHLSSCVSNYTSPDRCPSYTLRTSNGVESTLVLKEFPYRPLPGLDFRDGGTFLVPRGKLLDIIGAVGPTLPNKPTFMPGIAGIADVLRAWESLVVTVADGFDGRVSDTYKPKQPGETKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHP1</accession>
    <name>G5EHP1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGCH7_ch7g180</name>
        <name evidence="7" type="ORF">MGG_09016</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15</strain>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">70-15</strain>
        </source>
    </reference>
    <reference evidence="7" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721324.1">
        <property type="nucleotide sequence ID" value="XM_003721276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHP1"/>
    <dbReference type="STRING" id="242507.G5EHP1"/>
    <dbReference type="GeneID" id="2680139"/>
    <dbReference type="KEGG" id="mgr:MGG_09016"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09016"/>
    <dbReference type="eggNOG" id="ENOG502SZVV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_299580_0_0_1"/>
    <dbReference type="OMA" id="EYSAMDE"/>
    <dbReference type="OrthoDB" id="4161342at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="816"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="189"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EAQ70773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA46581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1001" mass="110497" checksum="96083C4EED1F050C" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="87" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHP8</accession>
    <name>G5EHP8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGCH7_ch7g572</name>
        <name evidence="12" type="ORF">MGG_02817</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15</strain>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <reference evidence="12" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720921.1">
        <property type="nucleotide sequence ID" value="XM_003720873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHP8"/>
    <dbReference type="SMR" id="G5EHP8"/>
    <dbReference type="FunCoup" id="G5EHP8">
        <property type="interactions" value="300"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EHP8"/>
    <dbReference type="GeneID" id="2682370"/>
    <dbReference type="KEGG" id="mgr:MGG_02817"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02817"/>
    <dbReference type="eggNOG" id="KOG1383">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019582_2_3_1"/>
    <dbReference type="OMA" id="KNIMQNC"/>
    <dbReference type="OrthoDB" id="5152799at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.160:FF:000005">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.50:FF:000001">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF3">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="526"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="561"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EAQ71165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA46178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="572" mass="63947" checksum="99129F5A7637E6DC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI12</accession>
    <name>G5EI12_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGCH7_ch7g593</name>
        <name evidence="9" type="ORF">MGG_02838</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15</strain>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">70-15</strain>
        </source>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720899.1">
        <property type="nucleotide sequence ID" value="XM_003720851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI12"/>
    <dbReference type="FunCoup" id="G5EI12">
        <property type="interactions" value="103"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EI12"/>
    <dbReference type="GeneID" id="2682391"/>
    <dbReference type="KEGG" id="mgr:MGG_02838"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02838"/>
    <dbReference type="eggNOG" id="KOG3322">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007205_0_0_1"/>
    <dbReference type="OMA" id="KALSPMC"/>
    <dbReference type="OrthoDB" id="442863at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039182">
        <property type="entry name" value="Pop1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055079">
        <property type="entry name" value="POP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009723">
        <property type="entry name" value="Pop1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012590">
        <property type="entry name" value="POPLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731:SF3">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22770">
        <property type="entry name" value="POP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06978">
        <property type="entry name" value="POP1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08170">
        <property type="entry name" value="POPLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pop1 N-terminal" evidence="5">
        <location>
            <begin position="65"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Pop1 N-terminal" evidence="5">
        <location>
            <begin position="259"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="POPLD" evidence="6">
        <location>
            <begin position="661"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="POP1 C-terminal" evidence="7">
        <location>
            <begin position="845"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="288"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="733"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="777"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="297"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="777"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="790"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EAQ71186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA46156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1023" mass="113312" checksum="D611ECB47CDC69B3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="88" xmlns="https://uniprot.org/uniprot">
    <accession>A4QXP0</accession>
    <name>A4QXP0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetylxylan esterase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_15403</name>
    </gene>
    <organism evidence="4 5">
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003713289.1"/>
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    <dbReference type="AlphaFoldDB" id="A4QXP0"/>
    <dbReference type="SMR" id="A4QXP0"/>
    <dbReference type="ESTHER" id="mago7-a4qxp0">
        <property type="family name" value="Acetylxylan_esterase"/>
    </dbReference>
    <dbReference type="GeneID" id="12986220"/>
    <dbReference type="KEGG" id="mgr:MGG_15403"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15403"/>
    <dbReference type="eggNOG" id="ENOG502SQ4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040058_4_2_1"/>
    <dbReference type="InParanoid" id="A4QXP0"/>
    <dbReference type="OMA" id="DPFCDSG"/>
    <dbReference type="OrthoDB" id="2586582at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630:SF9">
        <property type="entry name" value="CUTINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33630">
        <property type="entry name" value="CUTINASE RV1984C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002671906" description="Acetylxylan esterase 2" evidence="3">
        <location>
            <begin position="20"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="28252" checksum="0E0167D744C68729" modified="2007-05-15" version="1">MVSTRRIAGLLFAAVAARALPGEISQDGSARGGPMVVDAPITPPTSCAAGVQIFVVRGSTEPSHMGRIAPVATSIRDAVPGSFITALDYPAKINAAEYFFSVHRGVSRLAKLVRDYVKMCPQGKIALVGYSQGAHVVGDLVCGASSLPLYRSKPLDPVYNKNIIASLQFGDPSRRANQTWNVGTVTDRNGYFPRQRNKPCGPYSEAMRSWCDEKDRWCDKKSPTGTDREVHKKYQIKYKDAAADFVKKQWESSQKPLGS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2007-07-10" modified="2025-06-18" version="101" xmlns="https://uniprot.org/uniprot">
    <accession>A4RIF1</accession>
    <accession>G4MVD6</accession>
    <name>DBP5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>ATP-dependent RNA helicase DBP5</fullName>
            <ecNumber>3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">DBP5</name>
        <name type="ORF">MGG_07333</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Associates with the nuclear pore complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location>Nucleus</location>
            <location>Nuclear pore complex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="1">Nuclear pore complex cytoplasmic fibrils.</text>
    </comment>
    <comment type="domain">
        <text>The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715569.1">
        <property type="nucleotide sequence ID" value="XM_003715521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RIF1"/>
    <dbReference type="SMR" id="A4RIF1"/>
    <dbReference type="FunCoup" id="A4RIF1">
        <property type="interactions" value="764"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RIF1"/>
    <dbReference type="EnsemblFungi" id="MGG_07333T0">
        <property type="protein sequence ID" value="MGG_07333T0"/>
        <property type="gene ID" value="MGG_07333"/>
    </dbReference>
    <dbReference type="GeneID" id="2683229"/>
    <dbReference type="KEGG" id="mgr:MGG_07333"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07333"/>
    <dbReference type="eggNOG" id="KOG0332">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_1_0_1"/>
    <dbReference type="InParanoid" id="A4RIF1"/>
    <dbReference type="OMA" id="IAAETRW"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005934">
        <property type="term" value="C:cellular bud tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17963">
        <property type="entry name" value="DEADc_DDX19_DDX25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0509">mRNA transport</keyword>
    <keyword id="KW-0906">Nuclear pore complex</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0811">Translocation</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000294632" description="ATP-dependent RNA helicase DBP5">
        <location>
            <begin position="1"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="102"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="299"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="4">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEAD box" evidence="2">
        <location>
            <begin position="218"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="115"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="6"/>
    <sequence length="477" mass="51559" checksum="7F31B74232E320A6" modified="2012-01-25" version="2">MSDLASRITAPAAATPATETDAPAAASSTLAVPDGAADGANSSGLQESNYDVEVQLGDPDTDSPLSSISSFSELGLPQGIIDGLLAMNFKKPSKIQARALPLMLSNPPRNMIAQSQSGTGKTGAFVVTILSRVDFNQPNQPQALALAPSRELARQIQSVIQSIGQFCTGLVVDAAIPGAISRETGVKANVVVGTPGTVMDLIRRRQFDVSQLKLLVVDEADNMLDQQGLGEQCVRVKNMLPKTIQTLLFSATFPDHVKSYAEKFAPQANQMKLRQQELTVKGISQMYMDCPSLKEKYEVLCKLYGLMTIGSSVIFVKTRESADEIQRRMEADGHKVSALHGAFQGQERDQLLDDFRSGKSKVLITTNVLARGIDVSSVSMVINYDIPMKGPGDQSPDAETYLHRIGRTGRFGRVGVSISFVHDRKSFTALSSIAEHYGIDLIQLSPDDWDDTEVKVQDVIKSSRAKPDYAPTQEKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKE0</accession>
    <name>G4MKE0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_10538</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710141.1">
        <property type="nucleotide sequence ID" value="XM_003710093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKE0"/>
    <dbReference type="STRING" id="242507.G4MKE0"/>
    <dbReference type="GeneID" id="2682131"/>
    <dbReference type="KEGG" id="mgr:MGG_10538"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10538"/>
    <dbReference type="eggNOG" id="KOG1649">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014421_2_0_1"/>
    <dbReference type="InParanoid" id="G4MKE0"/>
    <dbReference type="OMA" id="VEVQGIW"/>
    <dbReference type="OrthoDB" id="10258327at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="233"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="480"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="508"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA57529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="589" mass="64621" checksum="EC7EA2816F177CD4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKR7</accession>
    <name>G4MKR7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAD binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_06662</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709369.1">
        <property type="nucleotide sequence ID" value="XM_003709321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKR7"/>
    <dbReference type="SMR" id="G4MKR7"/>
    <dbReference type="STRING" id="242507.G4MKR7"/>
    <dbReference type="GeneID" id="2684835"/>
    <dbReference type="KEGG" id="mgr:MGG_06662"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06662"/>
    <dbReference type="eggNOG" id="KOG1231">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018354_1_0_1"/>
    <dbReference type="InParanoid" id="G4MKR7"/>
    <dbReference type="OMA" id="KPACMFF"/>
    <dbReference type="OrthoDB" id="2151789at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF13">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465065" evidence="5">
        <location>
            <begin position="19"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="59"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA56757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="504" mass="54517" checksum="EA116B348362D1D0" modified="2011-12-14" version="1">MFVSSALSLTLLAQAVAAVSQTCDYLKANTKVLVETDRFAIPKAPYSAELDEYWSKASADLKPSCIVYPTSAEEASQAIRALSIDGNNETFAIKSGGLSANDGFNSVKDGPLISTRRLTGVRYDADKGFVRVATGNRWTEVQKQLDPFNVTVAGARVGEVGVGGYMSGGGFSFHSPRYGWGVNSLTGVEIVLANGTIVTASKTEHANLFAAVKGGTNNFGLVTAYIMEAIPIGQVWGGLMAFTGGDDKADKMMAAIAKFTNEFPDHPKAGIIPTVQLVLSGLIELWVVFFFYDGPTVPAGVFDDFLALRPLLNTCKTQNFGDLLAGNSAIVLRGTRYKVATETAILPDNAQDSAKVMRAYYDHWAATSREYKGAFGLTSSMAIQSVPKAMAAAARARGGDLIDMDDDVNRLIYEYDLSYLFAWDDDLVHRATMDMTAGMKKLVDGFVADGTTPDAFRPLFANDVYRGQDYFSRLRPEKRELAAKVSRDVDPSGLFRTRTGGWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKV2</accession>
    <name>G4MKV2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LYR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710199.1">
        <property type="nucleotide sequence ID" value="XM_003710151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKV2"/>
    <dbReference type="SMR" id="G4MKV2"/>
    <dbReference type="STRING" id="242507.G4MKV2"/>
    <dbReference type="GeneID" id="2676173"/>
    <dbReference type="KEGG" id="mgr:MGG_05358"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05358"/>
    <dbReference type="eggNOG" id="ENOG502S4S4">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141157_2_1_1"/>
    <dbReference type="InParanoid" id="G4MKV2"/>
    <dbReference type="OMA" id="HRAFMSK"/>
    <dbReference type="OrthoDB" id="10258445at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090324">
        <property type="term" value="P:negative regulation of oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20265">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045296">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052000">
        <property type="entry name" value="ETFRF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024:SF0">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024">
        <property type="entry name" value="GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="88" mass="10448" checksum="2486B03FCFA1D824" modified="2011-12-14" version="1">MPPPPNPELRRQVIAIYKELLNLGKDYPQGGLTYFRPRLHKAFMSNAHLRDEDKIREGIARAEFVQKEIEALYYLKRYRTLNKRYSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLJ8</accession>
    <name>G4MLJ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711131.1">
        <property type="nucleotide sequence ID" value="XM_003711083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLJ8"/>
    <dbReference type="GeneID" id="12986932"/>
    <dbReference type="KEGG" id="mgr:MGG_16561"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16561"/>
    <dbReference type="eggNOG" id="ENOG502SXXI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080469_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLJ8"/>
    <dbReference type="OMA" id="VECHQLP"/>
    <dbReference type="OrthoDB" id="5180903at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="292" mass="32033" checksum="F0BE776D560B0CC9" modified="2011-12-14" version="1">MFKWKILAHSAFASVFLSSVCTLILSAYALLNEDTVRSGIVTLRFDVTQILKLDALERRFPQQEGLLDGIRPGSRVSSILNNLQSAAGAVATSVPEIIKNIPKVISQAPQLISELVPKNCSLGTGEFCIQIGDKNSCDALPLDLSTFIEPEIVKVLKQHFQDIENVDATLTQITTPYFRHTLIAGVVLTGIATLLVVMSAYGRFTWLKKSKEILFSPKPIVFILRLLIGLLLCVPYIIPTLSLSMVRSKLDELPPWIEVENGDVFELLIGCTCCALFGAVISSAVHVFAEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMD8</accession>
    <name>G4MMD8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial</fullName>
            <ecNumber evidence="5">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_01995</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="5"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708736.1">
        <property type="nucleotide sequence ID" value="XM_003708688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMD8"/>
    <dbReference type="SMR" id="G4MMD8"/>
    <dbReference type="FunCoup" id="G4MMD8">
        <property type="interactions" value="698"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MMD8"/>
    <dbReference type="GeneID" id="2681114"/>
    <dbReference type="KEGG" id="mgr:MGG_01995"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01995"/>
    <dbReference type="eggNOG" id="KOG0784">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031953_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMD8"/>
    <dbReference type="OMA" id="TCAHKAN"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045242">
        <property type="term" value="C:isocitrate dehydrogenase complex (NAD+)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000001">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF42">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="13">
        <location>
            <begin position="49"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00071938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA56124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="386" mass="42044" checksum="BCEEC9CD521CC224" modified="2011-12-14" version="1">MLGTSRSAQCLVRAARKPQLFQASKQASRTFATVQSDIFKPSKYGGKYTVTLIPGDGIGAEVAESVKTIFKADNVPIEWEQVEVSGIADSAAPSGRTEDLFKESVASLRRNKLGLKGILHTPISRSGHQSFNVAMRQELDIYASISLIKNIPGYETRHKDVDLCIIRENTEGEYSGLEHQSVPGVVESLKIITRAKSERISKFAFSFALANNRKKVTCIHKANIMKLADGLFRSTFHQTAKEYPTLEANDMIVDNASMQCVSRPQQFDVLVMPNLYGGILSNIGAALVGGPGIVPGCNMGRDVAVFEPGCRHVGLDIKGKDQANPTALILSGSMLLRHLGLDDHANRISKAVYAVIAEGKTRTRDMGGEATTNQFTKAILDKMETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMM0</accession>
    <name>G4MMM0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidate phosphatase APP1 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_15175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710404.1">
        <property type="nucleotide sequence ID" value="XM_003710356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMM0"/>
    <dbReference type="STRING" id="242507.G4MMM0"/>
    <dbReference type="GeneID" id="12986316"/>
    <dbReference type="KEGG" id="mgr:MGG_15175"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15175"/>
    <dbReference type="eggNOG" id="ENOG502RYXR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030283_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMM0"/>
    <dbReference type="OMA" id="SWMSVAG"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052935">
        <property type="entry name" value="Mg2+_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208:SF1">
        <property type="entry name" value="FILAMENT ORGANIZATION PROTEIN APP1-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06650)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="APP1_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidate phosphatase APP1 catalytic" evidence="2">
        <location>
            <begin position="218"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="420" mass="47065" checksum="3F1C56272D6ADB7C" modified="2011-12-14" version="1">MADHTSSHHNSGSVPRQRAYCDEMQRKTREQCGFPKAESSLPDLSKSSKRVSSSSRGFSLGNILSFLGNRNPKPRPITAEDTVWLLDNVAFRDEASGRWTAEFVAVAMDQKPSVTPFDAVQAVARTIGLNETDEGIEILEQRLMPFLQDILPGREVVALHRGQQRLRLGPGGRNGISSDLRHLPDSTPGTVVNTVAQVPEGADGILTMKTFFAEPEGWAVVSDVDDTIKITQTSDPIGILRKTFLDEPTPVQGMPELYAWIQDKITPAAPWFYLSASPYNLYPFLTAFRDMYFPHGQLILRDQSWMSISGLLSNLTLGTEEYKVSRLQKVHDWLPKRKMILIGDSTQSDPEAYGEIYRGNPGWVKLILIRKVTDITSIGIESKNEPKRFEEAFEDVPKDAWHVFEDPAECQKHIERVLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMR6</accession>
    <name>G4MMR6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_02013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708758.1">
        <property type="nucleotide sequence ID" value="XM_003708710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMR6"/>
    <dbReference type="SMR" id="G4MMR6"/>
    <dbReference type="GeneID" id="2681639"/>
    <dbReference type="KEGG" id="mgr:MGG_02013"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02013"/>
    <dbReference type="HOGENOM" id="CLU_2085289_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMR6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="117" mass="12784" checksum="61B85C977888695F" modified="2011-12-14" version="1">MPPAPNAVANSQTPAWLSPLTQRQTPPPSPSTQLELKFSSVEQELQRINKDFVQSPLQDLESTVAAFQFENLVAGIEAKAAAAEARIGAIEDTISSLKGRIKEIRFYVFHKGLAQHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNG2</accession>
    <name>G4MNG2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 19">Mevalonate kinase</fullName>
            <shortName evidence="19">MK</shortName>
            <ecNumber evidence="3 19">2.7.1.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">MGG_16219</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17065"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.36"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:17066"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="18 19">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 19">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 19">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.36" evidence="3 19"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709688.1">
        <property type="nucleotide sequence ID" value="XM_003709640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNG2"/>
    <dbReference type="SMR" id="G4MNG2"/>
    <dbReference type="FunCoup" id="G4MNG2">
        <property type="interactions" value="433"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MNG2"/>
    <dbReference type="GeneID" id="12985238"/>
    <dbReference type="KEGG" id="mgr:MGG_16219"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16219"/>
    <dbReference type="eggNOG" id="KOG1511">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017814_1_0_1"/>
    <dbReference type="InParanoid" id="G4MNG2"/>
    <dbReference type="OMA" id="LMDFNHG"/>
    <dbReference type="OrthoDB" id="1652964at2759"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
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        <property type="entry name" value="Mevalonate kinase"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Mevalonate kinase"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
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        <property type="entry name" value="GHMP_kinase_C_sf"/>
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    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
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        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290:SF2">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 19" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 19" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14 19" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 19" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="16 19" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="13 19" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="15 19" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="20">
        <location>
            <begin position="170"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="21">
        <location>
            <begin position="346"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU363087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="EHA57076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="494" mass="54150" checksum="94603E924F84318B" modified="2011-12-14" version="1">MPPTTVTTNGIHKEVGELHINGNGNGIVKNQRARMARKQSSPMMPAFMVSAPGKVIVFGEHSVVYGKKAVAAAINLRSYLLVTALSKSKRTITLRFPDIDLIHTWNIDDLPWSTFSQPSKKKYYYDLVTSLDPDLMDAIQPHLEPVSSDAPDAQRKVHMSAAAAFLYLFMSLGSHAFPGGIYTLRSTIPIGAGLGSSASISACLSAALLLQIRTLSGPHPDQPPDEARVQVERINRWAFVAEMCIHGNPSGVDNTVSTQGKAVVFQRLDYARPPVVTPMWDFPELPLLVVDTKQAKSTKYEVEKVAKLRETHPKIVNSILDSMDKLTQAATDVLTDEDFDNEDVESLQKVGELMGMNHGLLVSLGVSHPRLERVRELVDHEGIGWTKLTGAGGGGCSITLMRPDVPREKLERLKERLDHEGYLKFRTTLGGGGVGVLWPAVLRNGMDEDDEGGMEIDVEKFLNADGNEGVERLVGVHGTSGEREGWKFWRVGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNS4</accession>
    <name>G4MNS4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708902.1">
        <property type="nucleotide sequence ID" value="XM_003708854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNS4"/>
    <dbReference type="GeneID" id="12985703"/>
    <dbReference type="KEGG" id="mgr:MGG_16036"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16036"/>
    <dbReference type="HOGENOM" id="CLU_2740512_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNS4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="71" mass="7863" checksum="926614545E15C855" modified="2011-12-14" version="1">MSPPQCDKKVEDPVEAEPEKQKCGLAEQPLRRTAALLHIPRLGTQGISCCSHTVRYMQLSCDPSSILGYLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNT6</accession>
    <name>G4MNT6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708914.1">
        <property type="nucleotide sequence ID" value="XM_003708866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNT6"/>
    <dbReference type="GeneID" id="12985707"/>
    <dbReference type="KEGG" id="mgr:MGG_16040"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16040"/>
    <dbReference type="HOGENOM" id="CLU_3087698_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNT6"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="52" mass="5402" checksum="EE75EAFD8A72EA32" modified="2011-12-14" version="1">MAKTESQATEVGPSPASATSTASASCPEDVCAPPRGDGQGIYELSRAHRDFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP93</accession>
    <name>G4MP93_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Endothiapepsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_02201</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708964.1">
        <property type="nucleotide sequence ID" value="XM_003708916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP93"/>
    <dbReference type="SMR" id="G4MP93"/>
    <dbReference type="GeneID" id="2681059"/>
    <dbReference type="KEGG" id="mgr:MGG_02201"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02201"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_0_1_1"/>
    <dbReference type="InParanoid" id="G4MP93"/>
    <dbReference type="OMA" id="KHWTIAV"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06097">
        <property type="entry name" value="Aspergillopepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034163">
        <property type="entry name" value="Aspergillopepsin-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF2">
        <property type="entry name" value="ASPERGILLOPEPSIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465261" evidence="8">
        <location>
            <begin position="22"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="91"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA56352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="429" mass="46467" checksum="98B9E384EE1C83A7" modified="2011-12-14" version="1">MRPFTQSFTLLTTLGAAAVSAGTVSVFKHDPPTRSGPLSIYNTRAKYGIPITPELSAAVSRAGFDVEKLDKRQQQQQGSAPARPYRNDTEWLNQVQVGTPPQNLTVQLDTGSAEFWVFADTHPTAKQAGRGVYSPSNSSTAALIPGITWSKGYVGGDSASGDAVYNDTVRVGDLVSQSQTILPATAASASYVNSSYDGILGLDLADYTATLPIEFKGPPNFFEAIKPSLPAPLFGVDLKQDKESFFDFGVIPPNRYRGDVGWTAINRFRVKDMDFTRWNMTVSAYSIGNVQTAPLKTRNMTGVADTGTTLMYLDKPVVQEYYSQVPGSRYDSTSAGWVFPCDGGPMPDFSFGVGPMESATVITVPGIYLNWTVNDQAKRECFGGLQEAINFQGASISLFGTVAMKAAYVIFEDRRPDADPRIGWAVKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPE4</accession>
    <name>G4MPE4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6590 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709809.1">
        <property type="nucleotide sequence ID" value="XM_003709761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPE4"/>
    <dbReference type="STRING" id="242507.G4MPE4"/>
    <dbReference type="GeneID" id="2680240"/>
    <dbReference type="KEGG" id="mgr:MGG_09196"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09196"/>
    <dbReference type="eggNOG" id="ENOG502SV73">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_717795_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPE4"/>
    <dbReference type="OMA" id="ENAGWHG"/>
    <dbReference type="OrthoDB" id="3559580at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046497">
        <property type="entry name" value="DUF6590"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35391:SF5">
        <property type="entry name" value="DUF6590 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20233">
        <property type="entry name" value="DUF6590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6590" evidence="2">
        <location>
            <begin position="220"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="385" mass="43328" checksum="AF83B768B2303CCC" modified="2011-12-14" version="1">MASRAKSKSKRNSDKREHSLYSNEAEPGFDYDERTLDHSHQYEEEEYANNTYEPHPGNYNEHHMDEQATTPRTKHSKDEGLSTSYECEETPDAGAHEATAALSDLTITNETSTENADGTEAQEDEVHDNQYGYTSKGKNKQTAGVEDEYGYEESAGFEISTKPAKQVTFGEANDYGDHYEMYEDTVEASKRDYYSLDQVGESSTAATDTYQGEHTEYTPEVFKTLWPEPMGTSSRYTTVVQAEEKGKSIHVSTRRFIIVGNADNQSYCVPIFTYGKQGCKKKGLKPHRHGMVYSGEVPPEPLKNEPQLGYDPVRVYMEPGQQDLMGESRVNYSMLCTVQHNVKALFIGFISQDELENVVQPAVYSILDGARGKTSKHSKERGKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPG3</accession>
    <name>G4MPG3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_05717</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710618.1">
        <property type="nucleotide sequence ID" value="XM_003710570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPG3"/>
    <dbReference type="STRING" id="242507.G4MPG3"/>
    <dbReference type="GeneID" id="2675903"/>
    <dbReference type="KEGG" id="mgr:MGG_05717"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05717"/>
    <dbReference type="eggNOG" id="KOG2246">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033556_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPG3"/>
    <dbReference type="OMA" id="PNKKWYL"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF40">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="13">
        <location>
            <begin position="197"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="12">
        <location>
            <begin position="389"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA58006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="466" mass="53450" checksum="CDD3FD99EB4BBA4F" modified="2011-12-14" version="1">MASMLRWRRRPRIALQYLAVVFAALSLFLLALPPDHPIILSARLATHKFLSHFPSLYNNDKWIFRPSQFPVDMHGDIATILKTGYGTWNRLPAQLEALGWALNETRGQGQSIMVVGDYSSHFQSDQHDFSVHDMLAAAEGSDALYGMERGNRLELYHRLNDAIRSGEDDVVHQLNREHGWELDAMKFIPALERAWKVFPRKKWYLMLDDDTYVIWPSLQLLLGHLDPSKPLYVGNAVGDYRKRFAHGGSAIVISGEAMRRLFDHRPDVVRAVYVDSLTEKWGDRLLAQAFLKLGIYIEERYSRFFNGERPRTTRITAEKFCAPLSSFHALARPGQMLEVGEKFRGITTPVFWGQLWRLYGQPDFRNLQQEDAISEGADHVGILDERVTTKKKVKSPEKCFRHCNHLKSCLAWRWEHETKTCHLAPWFIIGGENGSLQSGVSSGVHIARAKKLQEKCQRRGVMISDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPI2</accession>
    <name>G4MPI2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_05727</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710637.1">
        <property type="nucleotide sequence ID" value="XM_003710589.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MPI2"/>
    <dbReference type="GeneID" id="2676219"/>
    <dbReference type="KEGG" id="mgr:MGG_05727"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05727"/>
    <dbReference type="eggNOG" id="KOG0504">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002229_0_0_1"/>
    <dbReference type="InParanoid" id="G4MPI2"/>
    <dbReference type="OMA" id="GYNTPML"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="PHI-base" id="PHI:2009"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053210">
        <property type="entry name" value="ANKRD12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056485">
        <property type="entry name" value="ARM_KRIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056015">
        <property type="entry name" value="DUF7593"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24149:SF14">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24149">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24521">
        <property type="entry name" value="Ank_KRIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24513">
        <property type="entry name" value="DUF7593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="422"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="455"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="KRIT1 ARM-repeats" evidence="4">
        <location>
            <begin position="559"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7593" evidence="3">
        <location>
            <begin position="1252"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="510"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="705"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1538"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="326"/>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
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            <taxon>Pezizomycotina</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
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    </evidence>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Ebbole D.J."/>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="EMBL" id="EHA58193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="147" mass="16249" checksum="DC8BFD71EE7BED25" modified="2011-12-14" version="1">MKLTAIYLIASAVALQIGGVFGEDVPKHGQVDSRHGQGSSNHGNNKPDKQFLWGWRCQVALIEHVDGKKVEVGKVVTEIGGEGSLHNVQLGEKGYVRFKTRQNCYPDIIEGTMDGDRFELGHKRRWTVVRTTKVPGEDKAPLVAETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR48</accession>
    <name>G4MR48_PYRO7</name>
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            <fullName evidence="6">Adenylate cyclase</fullName>
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        <alternativeName>
            <fullName evidence="16">Adenylyl cyclase</fullName>
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    <gene>
        <name evidence="21" type="ORF">MGG_09898</name>
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    <organism evidence="21 22">
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
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    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="5"/>
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        <property type="protein sequence ID" value="EHA57380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003709944.1"/>
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    <dbReference type="SMR" id="G4MR48"/>
    <dbReference type="FunCoup" id="G4MR48">
        <property type="interactions" value="433"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MR48"/>
    <dbReference type="GeneID" id="2680942"/>
    <dbReference type="KEGG" id="mgr:MGG_09898"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09898"/>
    <dbReference type="eggNOG" id="KOG0532">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0618">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000430_4_0_1"/>
    <dbReference type="InParanoid" id="G4MR48"/>
    <dbReference type="OMA" id="QQVGYEE"/>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17214">
        <property type="entry name" value="RA_CYR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000408">
        <property type="entry name" value="Adenylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Adenylate cyclase AcyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000220">
        <property type="entry name" value="Adenylate cyclase AcyA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Adenylate cyclase AcyA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013716">
        <property type="entry name" value="Adenylate_cyclase_G-a-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055071">
        <property type="entry name" value="RA_PHLPP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF46">
        <property type="entry name" value="LEUCINE RICH REPEAT-CONTAINING DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08509">
        <property type="entry name" value="Ad_cyc_g-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23010">
        <property type="entry name" value="RA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00789">
        <property type="entry name" value="Ad_cyc_g-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="7" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ras-associating" evidence="19">
        <location>
            <begin position="495"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="20">
        <location>
            <begin position="1290"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="18">
        <location>
            <begin position="1630"/>
            <end position="1767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="176"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="970"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="17">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="316"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="389"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="976"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1020"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1058"/>
            <end position="1069"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EHA57380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="2017" mass="223092" checksum="7DE706CE4A53350B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR96</accession>
    <name>G4MR96_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_04709</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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        <location>
            <begin position="502"/>
            <end position="543"/>
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            <end position="27"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="EHA58256.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="543" mass="60910" checksum="56F4491C62593CD9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSF1</accession>
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        <recommendedName>
            <fullName evidence="5">DNA repair protein RAD50</fullName>
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        <name evidence="17" type="ORF">MGG_11387</name>
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    <organism evidence="17 18">
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMC family. RAD50 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713570.1">
        <property type="nucleotide sequence ID" value="XM_003713522.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MSF1"/>
    <dbReference type="FunCoup" id="G4MSF1">
        <property type="interactions" value="1011"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSF1"/>
    <dbReference type="GeneID" id="5051344"/>
    <dbReference type="KEGG" id="mgr:MGG_11387"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11387"/>
    <dbReference type="eggNOG" id="KOG0962">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006184_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSF1"/>
    <dbReference type="OMA" id="FSDYYYR"/>
    <dbReference type="OrthoDB" id="18797at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000947">
        <property type="entry name" value="DNA repair protein RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001195">
        <property type="entry name" value="DNA repair protein rad50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004584">
        <property type="entry name" value="Rad50_eukaryotes"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00606">
        <property type="entry name" value="rad50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13558">
        <property type="entry name" value="SbcC_Walker_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="16">
        <location>
            <begin position="6"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="218"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="280"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="400"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="477"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="580"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="721"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="854"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="981"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA53763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1316" mass="149429" checksum="0B3A81130BC09CE9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSS1</accession>
    <name>G4MSS1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sec1 family superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_12345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715299.1">
        <property type="nucleotide sequence ID" value="XM_003715251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSS1"/>
    <dbReference type="SMR" id="G4MSS1"/>
    <dbReference type="FunCoup" id="G4MSS1">
        <property type="interactions" value="784"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSS1"/>
    <dbReference type="GeneID" id="5050941"/>
    <dbReference type="KEGG" id="mgr:MGG_12345"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12345"/>
    <dbReference type="eggNOG" id="KOG1300">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009210_1_0_1"/>
    <dbReference type="InParanoid" id="G4MSS1"/>
    <dbReference type="OMA" id="PFTRPHT"/>
    <dbReference type="OrthoDB" id="2228at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="608"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="608"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="632"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="649"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="673"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="723"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="755" mass="84850" checksum="67D82DD502409EBB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTI2</accession>
    <name>G4MTI2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_15732</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase A1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714540.1">
        <property type="nucleotide sequence ID" value="XM_003714492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTI2"/>
    <dbReference type="SMR" id="G4MTI2"/>
    <dbReference type="FunCoup" id="G4MTI2">
        <property type="interactions" value="335"/>
    </dbReference>
    <dbReference type="MEROPS" id="A01.015"/>
    <dbReference type="GeneID" id="12984687"/>
    <dbReference type="KEGG" id="mgr:MGG_15732"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15732"/>
    <dbReference type="eggNOG" id="KOG1339">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013253_9_3_1"/>
    <dbReference type="InParanoid" id="G4MTI2"/>
    <dbReference type="OMA" id="TYLPQDM"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05474">
        <property type="entry name" value="SAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033876">
        <property type="entry name" value="SAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465381" description="Peptidase A1 domain-containing protein" evidence="9">
        <location>
            <begin position="21"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="10">
        <location>
            <begin position="62"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="315"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA54733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="484" mass="51589" checksum="354C163FF8E65E06" modified="2011-12-14" version="1">MLGISALLIVCASLGSFAAASDGVVQWHIERRQVPTPTAKLAKRVATTFEEVIQNEKSRGGYFAKCSVGGQDVTLQLDTGSSDLWVPAESACQSDRVPNGCSLGSFKKDLSSSFKVTGKDQFSIQYIDGSFARGDYFTDAFSIGGVRVINLTMGLGKQTDIPYGLAGVGYALNEAIVGGNSSNFTTYPNLPATMLNDGLINTNAFSLWLNNLDASTGRILFGGVDVAKFKGGMARIRIYEDVFSQEYMSFTVALTSLEAHSGSGQDTLTSRSFPIPVVLDSGTTLSYLPNDLAVQTWTEVGALYSAEYGQALLPCAMEDSKGYFVFGFAGPDGPKIQVEMKELVLDLTNGPAPKFTNGKYQGQDACTFGIQNFTGQTMVLGDTFLRSAYVVYDLVNHEIGIAQTDFNSTTSEIIAFPSSGAPIPSATLAPNQDQAVVKPQVTIPAFNAQPGFREGVSQATPLLKPLNKTHILLMCAAIALIMSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTZ4</accession>
    <name>G4MTZ4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">DNA replication complex GINS protein SLD5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_01611</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the GINS4/SLD5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714595.1">
        <property type="nucleotide sequence ID" value="XM_003714547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTZ4"/>
    <dbReference type="SMR" id="G4MTZ4"/>
    <dbReference type="FunCoup" id="G4MTZ4">
        <property type="interactions" value="638"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTZ4"/>
    <dbReference type="GeneID" id="2679312"/>
    <dbReference type="KEGG" id="mgr:MGG_01611"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01611"/>
    <dbReference type="eggNOG" id="KOG3176">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071893_1_1_1"/>
    <dbReference type="InParanoid" id="G4MTZ4"/>
    <dbReference type="OMA" id="ILETAWI"/>
    <dbReference type="OrthoDB" id="338231at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11711">
        <property type="entry name" value="GINS_A_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21692">
        <property type="entry name" value="GINS_B_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1030:FF:000006">
        <property type="entry name" value="DNA replication complex GINS protein SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008591">
        <property type="entry name" value="GINS_Sld5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031633">
        <property type="entry name" value="SLD5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038749">
        <property type="entry name" value="Sld5_GINS_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206">
        <property type="entry name" value="SLD5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16922">
        <property type="entry name" value="SLD5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007764">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="5 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="10">
        <location>
            <begin position="63"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein SLD5 C-terminal" evidence="11">
        <location>
            <begin position="167"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR007764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA54788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="221" mass="25191" checksum="04C63AA4691D7371" modified="2011-12-14" version="1">MEIDDILREVDPDFDALPSERRDLQLLTRAWVAERSAPELLEWPSDGLFERVNDRIKQQIEHVEDMTGNMDPKTNFALIVIQTELERYKFLVRSYLRARMAKIDKHTLHYLSTPSLRSRLSGTELAYATRHQALLHNHYLSSFLASFPPALQNLNDTAGNISMIDTPDLDSAVFIRLLRDAFVEGKGTDSDGAMEGRDGDILILRWSDAKHLVDEGNAELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU01</accession>
    <name>G4MU01_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myocyte-specific enhancer factor 2d</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_07199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715408.1">
        <property type="nucleotide sequence ID" value="XM_003715360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU01"/>
    <dbReference type="STRING" id="242507.G4MU01"/>
    <dbReference type="GeneID" id="2683182"/>
    <dbReference type="KEGG" id="mgr:MGG_07199"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07199"/>
    <dbReference type="eggNOG" id="ENOG502RP3A">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030123_0_0_1"/>
    <dbReference type="InParanoid" id="G4MU01"/>
    <dbReference type="OMA" id="QANHTAP"/>
    <dbReference type="OrthoDB" id="128867at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052254">
        <property type="entry name" value="CUL4-DDB1_E3_ligase_receptor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472:SF1">
        <property type="entry name" value="DDB1 AND CUL4 ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="568" mass="61807" checksum="7C3731ED33CB842D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV31</accession>
    <name>G4MV31_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L28e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_08834</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713853.1">
        <property type="nucleotide sequence ID" value="XM_003713805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV31"/>
    <dbReference type="SMR" id="G4MV31"/>
    <dbReference type="STRING" id="242507.G4MV31"/>
    <dbReference type="GeneID" id="2679820"/>
    <dbReference type="KEGG" id="mgr:MGG_08834"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08834"/>
    <dbReference type="eggNOG" id="KOG3412">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106801_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV31"/>
    <dbReference type="OMA" id="GKYGQRP"/>
    <dbReference type="OrthoDB" id="338850at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.110:FF:000002">
        <property type="entry name" value="60S ribosomal protein L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002672">
        <property type="entry name" value="Ribosomal_eL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10544">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="5">
        <location>
            <begin position="8"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA54046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="151" mass="16368" checksum="9DA66828EF13210B" modified="2011-12-14" version="1">MSNVSADLIWEVVRNQNAFLEKRNTNGGVQFSRDPLNLTNKHSRKYAGFVNDKAIGVQASSNEKGGVAITSKKAGAGNKPASSQTTTTFRPHKNNRSTFKAVANQTAKNGYRADLRQAAVARTSAILKSQRPVKAEPEKKLRGNAAKKDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV54</accession>
    <name>G4MV54_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">intramembrane prenyl-peptidase Rce1</fullName>
            <ecNumber evidence="10">3.4.26.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_08854</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic sidechains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.26.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase U48 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.26.1" evidence="10"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713876.1">
        <property type="nucleotide sequence ID" value="XM_003713828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV54"/>
    <dbReference type="FunCoup" id="G4MV54">
        <property type="interactions" value="293"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MV54"/>
    <dbReference type="MEROPS" id="G05.002"/>
    <dbReference type="GeneID" id="2679840"/>
    <dbReference type="KEGG" id="mgr:MGG_08854"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08854"/>
    <dbReference type="eggNOG" id="KOG4130">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049909_1_0_1"/>
    <dbReference type="InParanoid" id="G4MV54"/>
    <dbReference type="OMA" id="HSFCNWC"/>
    <dbReference type="OrthoDB" id="271604at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039731">
        <property type="entry name" value="Rce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046:SF0">
        <property type="entry name" value="CAAX PRENYL PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046">
        <property type="entry name" value="PROTEASE U48 CAAX PRENYL PROTEASE RCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="12">
        <location>
            <begin position="151"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA54069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="323" mass="35939" checksum="97FC8E05B35FB0D4" modified="2011-12-14" version="1">MPSVRGILDKLIGKKPVETPPPITTRTAVLLLILYTFVYVVPFYLSSRTRPSAQLSRDAPSVIRARITSVLISCLICSLATFYVVTKDGQISPMGALRMMGYWPVGFVETAKSLVLTMLLFLGPLFEYFVVERGWREWIALTPVYELFGEWTTWRNIVAGPVTEEILFRSAGIPLMLLAKTSVTKTIFLTPIIFGLAHMNHFYEFRISHPQVPVAAAALRSVFQFCFTTLFGAYATFVFLRGGSLLSVCLIHAFCNSMGLPRLWGRVEPSAAAGEFAEDGQTRKPKATGLTVAYYLLLVTGAVLFYQNIFLLTKSPLELAVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV79</accession>
    <name>G4MV79_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_15600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713901.1">
        <property type="nucleotide sequence ID" value="XM_003713853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV79"/>
    <dbReference type="SMR" id="G4MV79"/>
    <dbReference type="STRING" id="242507.G4MV79"/>
    <dbReference type="GeneID" id="12987307"/>
    <dbReference type="KEGG" id="mgr:MGG_15600"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15600"/>
    <dbReference type="eggNOG" id="KOG0151">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007957_0_0_1"/>
    <dbReference type="InParanoid" id="G4MV79"/>
    <dbReference type="OMA" id="VWYRWKL"/>
    <dbReference type="OrthoDB" id="377209at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051485">
        <property type="entry name" value="SR-CTD_assoc_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140">
        <property type="entry name" value="RNA PROCESSING PROTEIN LD23810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140:SF0">
        <property type="entry name" value="U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CID" evidence="3">
        <location>
            <begin position="479"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="450"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="768"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="826" mass="90435" checksum="BF401A9F5D402856" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVH6</accession>
    <name>G4MVH6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07368</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715609.1">
        <property type="nucleotide sequence ID" value="XM_003715561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVH6"/>
    <dbReference type="STRING" id="242507.G4MVH6"/>
    <dbReference type="GeneID" id="2683087"/>
    <dbReference type="KEGG" id="mgr:MGG_07368"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07368"/>
    <dbReference type="eggNOG" id="ENOG502SI0U">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020030_2_0_1"/>
    <dbReference type="InParanoid" id="G4MVH6"/>
    <dbReference type="OMA" id="WTCRSRT"/>
    <dbReference type="OrthoDB" id="5130013at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021858">
        <property type="entry name" value="Fun_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN UGA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37534:SF15">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11951">
        <property type="entry name" value="Fungal_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA55802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="630" mass="68346" checksum="6575E88B71AECA60" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVH9</accession>
    <name>G4MVH9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminomethyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_12421</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715612.1">
        <property type="nucleotide sequence ID" value="XM_003715564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVH9"/>
    <dbReference type="SMR" id="G4MVH9"/>
    <dbReference type="STRING" id="242507.G4MVH9"/>
    <dbReference type="GeneID" id="5051015"/>
    <dbReference type="KEGG" id="mgr:MGG_12421"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12421"/>
    <dbReference type="eggNOG" id="KOG2844">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_11_2_1"/>
    <dbReference type="InParanoid" id="G4MVH9"/>
    <dbReference type="OMA" id="MVFKYDQ"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032503">
        <property type="entry name" value="FAO_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF2">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16350">
        <property type="entry name" value="FAO_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase central" evidence="5">
        <location>
            <begin position="373"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="GCVT N-terminal" evidence="3">
        <location>
            <begin position="436"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="4">
        <location>
            <begin position="738"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="831" mass="89012" checksum="65E07E99FC72ED54" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVM1</accession>
    <name>G4MVM1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome assembly factor mrt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_08908</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Associates with the pre-60S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA54130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713937.1">
        <property type="nucleotide sequence ID" value="XM_003713889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVM1"/>
    <dbReference type="SMR" id="G4MVM1"/>
    <dbReference type="FunCoup" id="G4MVM1">
        <property type="interactions" value="1055"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MVM1"/>
    <dbReference type="GeneID" id="2679894"/>
    <dbReference type="KEGG" id="mgr:MGG_08908"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08908"/>
    <dbReference type="eggNOG" id="KOG0816">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071690_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVM1"/>
    <dbReference type="OMA" id="LEWAENY"/>
    <dbReference type="OrthoDB" id="10262308at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05796">
        <property type="entry name" value="Ribosomal_P0_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1730:FF:000005">
        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000003">
        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033867">
        <property type="entry name" value="Mrt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051742">
        <property type="entry name" value="Ribosome_Assembly_uL10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841:SF1">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 MRTO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="126"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="251" mass="27623" checksum="39FE03AFE7BB3F1B" modified="2011-12-14" version="1">MPKSKRAKVVHMTNVAKKTREQKELLFTNIRECVPQYQHLFVFSVDNMRNNNLKDVRRELSGDSRMFFGKTKLMARALGQTAEDEQAEGLHKLTSHLAGTVGLIFTNRPASELLSYLDSITSVDFARAGAVAPRDFSIPPGVVYSTGGEVPQEYDVPLAHSIEPELRKLGVPTRLIKGRVVLGGENGEGSTGYDVCREGDVLDSRQTRLLKLFSVCFSEFKIQVLAYWSAATGEVTEVNPGSAGDAIDDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWE9</accession>
    <name>G4MWE9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715716.1">
        <property type="nucleotide sequence ID" value="XM_003715668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWE9"/>
    <dbReference type="GeneID" id="2678611"/>
    <dbReference type="KEGG" id="mgr:MGG_08346"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08346"/>
    <dbReference type="eggNOG" id="ENOG502RMKR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_778609_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWE9"/>
    <dbReference type="OrthoDB" id="5220886at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA55909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="356" mass="40438" checksum="A308BB07F5B5CF61" modified="2011-12-14" version="1">MPPVKGGLKPRKQGTVHGARPKQAPYSPRDSEQVAITILAILSNILFASCFHFVGNTTLKKRKYKWRDLINPKLGRKKVSQCDKVEWKPSSTIFLQEHSRDPSLVRILTHTKDMLNMVEDGDLVKIYVCLFDKKTETPNPANLVELFTLQVRYEPDMSTTVTVSWAGLTQLLPKSSVKTKNKGGLSIEEFLQHLQPIKKKVYTLIKHQFKESKRAKWGSRSKKSNFDLLVAKELLLERPECNTWTECVAVGIPARKSPAEDIDGSEEEQTVHVEVEKPTSPLETFSHGQKRRLHLFSDDKDTLRNPPAKVRIDWTEGSEGSWGIDGASDNSSVRNRRLETSPVARASQRLRFEAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWH6</accession>
    <name>G4MWH6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714031.1">
        <property type="nucleotide sequence ID" value="XM_003713983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWH6"/>
    <dbReference type="GeneID" id="2679977"/>
    <dbReference type="KEGG" id="mgr:MGG_08992"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08992"/>
    <dbReference type="HOGENOM" id="CLU_2210548_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWH6"/>
    <dbReference type="OrthoDB" id="10385304at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005680468" evidence="1">
        <location>
            <begin position="24"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="107" mass="11937" checksum="2EEFD2ABF2B5A75D" modified="2011-12-14" version="1">MKFNNLLAPAVIASASLAGQAAAFPWDERVCQVTVFYPGKETGTLMPHLMEPEEPIVIPKINGKRYYAVSDANCKYKRYDVDPEGNPWPSGLRVKGVAVKLWKEKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX86</accession>
    <name>G4MX86_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715791.1">
        <property type="nucleotide sequence ID" value="XM_003715743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX86"/>
    <dbReference type="SMR" id="G4MX86"/>
    <dbReference type="STRING" id="242507.G4MX86"/>
    <dbReference type="GeneID" id="2678642"/>
    <dbReference type="KEGG" id="mgr:MGG_08291"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08291"/>
    <dbReference type="eggNOG" id="ENOG502S40X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053381_7_1_1"/>
    <dbReference type="InParanoid" id="G4MX86"/>
    <dbReference type="OMA" id="HCIAGMV"/>
    <dbReference type="OrthoDB" id="2331100at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052953">
        <property type="entry name" value="Ser-rich/MCO-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883:SF20">
        <property type="entry name" value="PHYTOCYANIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34883">
        <property type="entry name" value="SERINE-RICH PROTEIN, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465485" description="Extracellular serine-rich protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="15958" checksum="B4E81B31F8346607" modified="2011-12-14" version="1">MQFKAVLLAVASVACVHAAETHKVNVGESGLSFSPEEVKAAKGDTIEFHFFSSSHDAVMGLADRPCEAMGMMDGSFASGVPEGDQVKQVFRVEVNSTEPALVFCSVGMHCANGMVMAINPNGEKTATKFKDAARGKASKAPEGVYGGTWGNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXG3</accession>
    <name>G4MXG3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713300.1">
        <property type="nucleotide sequence ID" value="XM_003713252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXG3"/>
    <dbReference type="GeneID" id="12986167"/>
    <dbReference type="KEGG" id="mgr:MGG_15498"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15498"/>
    <dbReference type="HOGENOM" id="CLU_1777854_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXG3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="146" mass="16898" checksum="82DCFCDC733217C9" modified="2011-12-14" version="1">MLGPYFAFACCRGDQRPWDNWVPESSYRQRQRKEGGTRKKVPGAPSLPIYREYKSIDPRYCNHQRSKEQKSARSSLHPGYNDPSGATFLDDDLGRYYEQFLRGRLVWVYVVGIEHHELVEKHQDDISSSKRLNVGGDQPQNEHGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXS7</accession>
    <name>G4MXS7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinetochore protein fta4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715021.1">
        <property type="nucleotide sequence ID" value="XM_003714973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXS7"/>
    <dbReference type="SMR" id="G4MXS7"/>
    <dbReference type="STRING" id="242507.G4MXS7"/>
    <dbReference type="GeneID" id="12985511"/>
    <dbReference type="KEGG" id="mgr:MGG_15811"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15811"/>
    <dbReference type="eggNOG" id="ENOG502S9QD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058478_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXS7"/>
    <dbReference type="OMA" id="KQHNRIV"/>
    <dbReference type="OrthoDB" id="21214at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031511">
        <property type="term" value="C:Mis6-Sim4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025207">
        <property type="entry name" value="Sim4_Fta4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42040">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT FTA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42040:SF1">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT FTA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13093">
        <property type="entry name" value="FTA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="31366" checksum="6DA9C56C22EAF034" modified="2011-12-14" version="1">MSSAAPPTILTLKQELIAEQVRLLSQPLAPSRAWRAGNNASAQAAGDNGGSAAGATIPERAVEAAMVRVNHRLHQHVNRVYASAATRHVAEQLEQLYLIERERATELHPEGNELQAMGISSSTDFADAKTISALPENWPLEKDAETYPVEVKRFAELAESLKELSVEREALLLRVRRLRALRDGLAPFQASTDDTVDDNAAAAHVQRHLVTKNGELEQELERTRILMARVGGRVARLIQKESQNKASTVGSNDEDSLFEDREDSVPVALEEDARRKVNDLLDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXU0</accession>
    <name>G4MXU0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715837.1">
        <property type="nucleotide sequence ID" value="XM_003715789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXU0"/>
    <dbReference type="GeneID" id="12986783"/>
    <dbReference type="KEGG" id="mgr:MGG_15962"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15962"/>
    <dbReference type="InParanoid" id="G4MXU0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="217" mass="24148" checksum="2017949AFDF8336B" modified="2011-12-14" version="1" fragment="single">MHDRISHWIDRLPVTAEKDVKRKRCEYPQTRSIDLPTPPATQICRFTGDVPPSPIINTPPTKRQRNFPSHQTEVEEVEQTPRPTVAALRGNVSLSYSTSSRATSKRSSSPRKRQAELEVELEEAIQVRSLANGRLPDELFSLVSELEKAASGDTPVLHASLKQELKYAEEKAKERRALGYRIPDSAFTSGEEDTTGDLITDVPASSVCEVLLAALRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXZ5</accession>
    <name>G4MXZ5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_15509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713330.1">
        <property type="nucleotide sequence ID" value="XM_003713282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXZ5"/>
    <dbReference type="STRING" id="242507.G4MXZ5"/>
    <dbReference type="GeneID" id="12986189"/>
    <dbReference type="KEGG" id="mgr:MGG_15509"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15509"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_799439_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXZ5"/>
    <dbReference type="OMA" id="MDIRARE"/>
    <dbReference type="OrthoDB" id="21416at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GPIID_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056884">
        <property type="entry name" value="NPHP3-like_N"/>
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    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="PANTHER" id="PTHR10039">
        <property type="entry name" value="AMELOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10039:SF14">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24883">
        <property type="entry name" value="NPHP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22939">
        <property type="entry name" value="WHD_GPIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nephrocystin 3-like N-terminal" evidence="3">
        <location>
            <begin position="5"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase winged helix" evidence="2">
        <location>
            <begin position="267"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA53523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="347" mass="39511" checksum="CDE7BDEBBC520CDD" modified="2011-12-14" version="1">MYCQTPLLWLNGKPGSGKSVLASLIIEEARKLPDISVAFFYCNESDPATRDFVAIARSILAQLLAQDDSLLLHLEHRMSTPTGKAPQAVLSDMKLAKELLTVALRSRKTYIILDGIDECDRNQRKEICRWYREVVEGLPRLKYDEIRCLFISQDDGVGRKDLSSLSTLRLTPESNLEDIKAFSKHWQGQIERRFDSVKKHNLDFTEIVAARSQGMFIFARCVFEELYNQPSGQAVLDEWREDRFPKDLEDLYERILLRIIGTGTANQQDASKKLLSWIAVARRPLRWYEIQASYSINLDDETINTEEGRLRGTAKDHCASFVDVRADQTVSFVHGTVKSSSSSSSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MY81</accession>
    <name>G4MY81_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Spermine/spermidine synthase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_01296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714219.1">
        <property type="nucleotide sequence ID" value="XM_003714171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MY81"/>
    <dbReference type="SMR" id="G4MY81"/>
    <dbReference type="GeneID" id="2679577"/>
    <dbReference type="KEGG" id="mgr:MGG_01296"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01296"/>
    <dbReference type="eggNOG" id="ENOG502QTVA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017511_2_0_1"/>
    <dbReference type="InParanoid" id="G4MY81"/>
    <dbReference type="OMA" id="CFIGWAG"/>
    <dbReference type="OrthoDB" id="2016285at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000288">
        <property type="entry name" value="Spermine/spermidine synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037959">
        <property type="entry name" value="MFS_SpdSyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43317:SF1">
        <property type="entry name" value="THERMOSPERMINE SYNTHASE ACAULIS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="66065" checksum="954F4F3319957C9B" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZP9</accession>
    <name>G4MZP9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715220.1">
        <property type="nucleotide sequence ID" value="XM_003715172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZP9"/>
    <dbReference type="SMR" id="G4MZP9"/>
    <dbReference type="GeneID" id="12985591"/>
    <dbReference type="KEGG" id="mgr:MGG_15841"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15841"/>
    <dbReference type="HOGENOM" id="CLU_2134002_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZP9"/>
    <dbReference type="OrthoDB" id="10400686at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="113" mass="12448" checksum="B5102EAFE126AFAB" modified="2011-12-14" version="1">MSSQTSKNNTPSTPATSSKAAQKAPARPKDDSDSEDEEDQLRRQVAQTNQEFHEQTLRATQLQEELQAFRASANVTSTPLDGRERFKLNPPATFDGTPGQFKGYFVQGHTPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N059</accession>
    <name>G4N059_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712901.1">
        <property type="nucleotide sequence ID" value="XM_003712853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N059"/>
    <dbReference type="GeneID" id="5051816"/>
    <dbReference type="KEGG" id="mgr:MGG_14463"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14463"/>
    <dbReference type="HOGENOM" id="CLU_1475455_0_0_1"/>
    <dbReference type="InParanoid" id="G4N059"/>
    <dbReference type="OrthoDB" id="5221804at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="183" mass="19310" checksum="B43ADB07913E0862" modified="2011-12-14" version="1">MGIRNLLSCCGGWTRSESIGSKDLSDPSDRFTAARPRAPAITITTSDGDSSSFGTTGLRQPRDSASGRKRSLKPIDEEEQAAIRRYKSLVQDRKPSELNSLYFGEEGPGSDMVGRRVSGGGGGGGGVQQQESKGKASSMPYGNDSSGFPNNGVSSGHGGLVMYQHVTSGGSLQYDYAGTREDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1B8</accession>
    <name>G4N1B8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712196.1">
        <property type="nucleotide sequence ID" value="XM_003712148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1B8"/>
    <dbReference type="SMR" id="G4N1B8"/>
    <dbReference type="GeneID" id="2680443"/>
    <dbReference type="KEGG" id="mgr:MGG_09545"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09545"/>
    <dbReference type="eggNOG" id="ENOG502QRGR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032158_1_1_1"/>
    <dbReference type="InParanoid" id="G4N1B8"/>
    <dbReference type="OMA" id="GSMPVCH"/>
    <dbReference type="OrthoDB" id="5402974at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031563">
        <property type="entry name" value="MOT1/MOT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31970:SF9">
        <property type="entry name" value="MOLYBDATE TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16983">
        <property type="entry name" value="MFS_MOT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="46371" checksum="D73206FBE8D484FD" modified="2011-12-14" version="1">MAIKDIPKLNRNSIRTLRHDPLSEISGALGDLGTLLPLMIALALQSSISLSTTLVFSGIFNVLTGIVFGIPLPVQPMKAIAAAAIAEHTSLRQTVAAGGLVSAAVLILSATGLLRRATRLIPVPVAKGIQFGAGLSLVISAGSSLLQPLHWLHPILDNRLWAFGALVGLVVTHRFRRVPYALIVFILGTAFAAVAVATSGRNLRLPGVAPWVPFLVLPAWTSPVAISMAVAQLPLTTLNSVIAVSALSADLLPNLPTPTVTEMGLSVASMNLIGCWFGAMPVCHGAGGLAAQHRFGARSGASIIILGIFKILLGLILGETLLDLLDRFPHALLGIMVLASGLELAGVGQSLNHGAADLWESSMEGNAPEALSTRIHRSLSEEERAERWSVMLITTAGILAFKNDAVGFAAGMLSHWTYRAAQHWGRGTGERQPLISRPFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1L6</accession>
    <name>G4N1L6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_07487</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711395.1">
        <property type="nucleotide sequence ID" value="XM_003711347.1"/>
    </dbReference>
    <dbReference type="FunCoup" id="G4N1L6">
        <property type="interactions" value="228"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N1L6"/>
    <dbReference type="GeneID" id="2683407"/>
    <dbReference type="KEGG" id="mgr:MGG_07487"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07487"/>
    <dbReference type="eggNOG" id="KOG0298">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001592_2_0_1"/>
    <dbReference type="InParanoid" id="G4N1L6"/>
    <dbReference type="OMA" id="KAVFFCA"/>
    <dbReference type="OrthoDB" id="5330228at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="DEXQc_SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
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    <dbReference type="InterPro" id="IPR059033">
        <property type="entry name" value="C144_05_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26021">
        <property type="entry name" value="Ferritin_C144_05"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="317"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="1160"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="735"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1220"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="735"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="753"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1228"/>
            <end position="1246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA51588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1514" mass="171216" checksum="D38A12E6D4154CB9" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1S5</accession>
    <name>G4N1S5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Membrane anchor Opy2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_09497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712247.1">
        <property type="nucleotide sequence ID" value="XM_003712199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1S5"/>
    <dbReference type="SMR" id="G4N1S5"/>
    <dbReference type="STRING" id="242507.G4N1S5"/>
    <dbReference type="GeneID" id="2680534"/>
    <dbReference type="KEGG" id="mgr:MGG_09497"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09497"/>
    <dbReference type="eggNOG" id="ENOG502RY3X">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030352_1_0_1"/>
    <dbReference type="InParanoid" id="G4N1S5"/>
    <dbReference type="OMA" id="TVPLDCT"/>
    <dbReference type="OrthoDB" id="2402916at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="45206" checksum="BEA5DD096A6695DF" modified="2011-12-14" version="1">MAYLAMSGAVPIDTLVRRDPGCPDFVLADCPVPGPCNLQCAEGQSCQRKSPSSCNCATNFCGVDPAAITSPNIPQPQVSSSSSSGPSVGAIAGGVIGGVAAIGLITYLVWRFCIKTKRDPMERESWLEEKRNGDLEADDMTARRTHRSSTHTSHSVASTVLTRASNIIQIAYIPGVTNRATPTSPTILVPPVPPIPIAVSQASTPSAPEDQHFFMPSDLRPDSTYSAMTGYTDRTSFARTSYAPRSSIASTIYGKNAVIVAPAQTGMRAKPAMVSVKSTGSGTSTGSSTPPVPDIDFEKYGTVRPPSPANSTFSVGSTFLNNASAHTAMAARPQVVRVGSVSKKSSNLARTISAADSTPSSITGNTDQSPSNADQGPFADPPRPSTNRSNKAISAVIQEATRRASQRDMTTPSRSDRERSPFGDEHVARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1S7</accession>
    <name>G4N1S7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein 2/3 complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_09495</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ARPC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712249.1">
        <property type="nucleotide sequence ID" value="XM_003712201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1S7"/>
    <dbReference type="SMR" id="G4N1S7"/>
    <dbReference type="FunCoup" id="G4N1S7">
        <property type="interactions" value="496"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N1S7"/>
    <dbReference type="GeneID" id="2680532"/>
    <dbReference type="KEGG" id="mgr:MGG_09495"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09495"/>
    <dbReference type="eggNOG" id="KOG3380">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101888_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1S7"/>
    <dbReference type="OMA" id="LWHEKAF"/>
    <dbReference type="OrthoDB" id="429520at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.190">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006789">
        <property type="entry name" value="ARPC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036743">
        <property type="entry name" value="ARPC5_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12644">
        <property type="entry name" value="ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04699">
        <property type="entry name" value="P16-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039096">
        <property type="entry name" value="p16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69103">
        <property type="entry name" value="Arp2/3 complex 16 kDa subunit ARPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="137"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA52442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="202" mass="21750" checksum="2138B9C31A5C49C0" modified="2011-12-14" version="1">MSIIQHHTSASLTDAWRTINIDALTEDSSVNFDTSTLRPPLPEVSDAEVRQLAQQIRQLLRGGDPEGALRGCLEMPVYQADEPVKDAHLQTVIEVLQSIKASDMTPMLNRIYGSDGGSELLDVLMKYIYKGMAAASSNGNPRTPTKVTPQATGGFSQVGSRPGAANESAGAGMSVLLSWHEKVVEVAGLGCIGRVMTDWRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N277</accession>
    <name>G4N277_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_09458</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712296.1">
        <property type="nucleotide sequence ID" value="XM_003712248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N277"/>
    <dbReference type="SMR" id="G4N277"/>
    <dbReference type="FunCoup" id="G4N277">
        <property type="interactions" value="355"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N277"/>
    <dbReference type="GeneID" id="2680501"/>
    <dbReference type="KEGG" id="mgr:MGG_09458"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09458"/>
    <dbReference type="eggNOG" id="KOG2698">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049768_1_3_1"/>
    <dbReference type="InParanoid" id="G4N277"/>
    <dbReference type="OMA" id="VAHAIME"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.10:FF:000003">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000012">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="13">
        <location>
            <begin position="130"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA52489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="310" mass="34371" checksum="4C50560F4970164F" modified="2011-12-14" version="1">MGRADDRTSPAASSSSSSGNSGTKRSRKHRDDEPAAGATEHTKKKHKKRKSDHGVNGVIKSSQRRLSLSNAARDPRDEPPPKPKKKPEAPTRSPSPLIDFDGLSRPSVGTRARLEETPEQAAERLERMRGAVRTLLECVGEDPDRQGLLATPDRYAKALLFLTKGYQENIKDIVNNAIFHEGHNEMVIVKDIEIFSMCEHHLVPFTGKMHIGYIPANSVIGLSKLPRIAELFARRLQIQERLTKEVANAIFEVLKPQGVAVVMESSHLCMVTRGVQKTTATTITSCVLGCFEGRERTRNEFLSLIGVNRH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-02-13" modified="2025-06-18" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2B5</accession>
    <name>ABC7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ABC transporter 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pyriculol/pyriculariol biosynthesis cluster protein ABC7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ABC7</name>
        <name type="ORF">MGG_04855</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2017" name="Microbiology" volume="163" first="541" last="553">
            <title>Unravelling the biosynthesis of pyriculol in the rice blast fungus Magnaporthe oryzae.</title>
            <authorList>
                <person name="Jacob S."/>
                <person name="Groetsch T."/>
                <person name="Foster A.J."/>
                <person name="Schueffler A."/>
                <person name="Rieger P.H."/>
                <person name="Sandjo L.P."/>
                <person name="Liermann J.C."/>
                <person name="Opatz T."/>
                <person name="Thines E."/>
            </authorList>
            <dbReference type="PubMed" id="27902426"/>
            <dbReference type="DOI" id="10.1099/mic.0.000396"/>
        </citation>
        <scope>IDENTIFICATION</scope>
        <scope>FUNCTION</scope>
    </reference>
    <comment type="function">
        <text evidence="6 9">ABC transporter; part of the gene cluster that mediates the biosynthesis of pyriculol and pyriculariol, two heptaketides that induce lesion formation upon application on rice leaves but are dispensable for pathogenicity (PubMed:27902426). With the MFS transporter MFS1, is most likely responsible for pyriculol and pyriculariol secretion and thereby may contribute to intrinsic resistance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily.</text>
    </comment>
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        <property type="nucleotide sequence ID" value="XM_003712286.1"/>
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    <dbReference type="STRING" id="242507.G4N2B5"/>
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        <property type="glycosylation" value="10 sites, No reported glycans"/>
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        <property type="gene ID" value="MGG_04855"/>
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        <property type="component" value="Chromosome 3"/>
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        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
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        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC1_TM_dom"/>
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    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
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    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
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    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
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    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
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    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
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    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
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    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
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    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
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    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000446274" description="ABC transporter 7">
        <location>
            <begin position="1"/>
            <end position="1683"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1 3">
        <location>
            <begin position="336"/>
            <end position="356"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1 3">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1 3">
        <location>
            <begin position="496"/>
            <end position="516"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1 3">
        <location>
            <begin position="518"/>
            <end position="538"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1 3">
        <location>
            <begin position="602"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1 3">
        <location>
            <begin position="632"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1016"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1 3">
        <location>
            <begin position="1111"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1 3">
        <location>
            <begin position="1182"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1 3">
        <location>
            <begin position="1204"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1 3">
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            <begin position="1304"/>
            <end position="1324"/>
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    <feature type="transmembrane region" description="Helical" evidence="1 3">
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            <begin position="1327"/>
            <end position="1347"/>
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    </feature>
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            <begin position="338"/>
            <end position="664"/>
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    </feature>
    <feature type="domain" description="ABC transporter 1" evidence="2">
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            <end position="949"/>
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    <feature type="domain" description="ABC transmembrane type-1 2" evidence="3">
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            <begin position="1028"/>
            <end position="1351"/>
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    </feature>
    <feature type="domain" description="ABC transporter 2" evidence="2">
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            <end position="93"/>
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    <feature type="region of interest" description="Disordered" evidence="5">
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            <end position="473"/>
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    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="952"/>
            <end position="998"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
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    <feature type="binding site" evidence="2">
        <location>
            <begin position="742"/>
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        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    <feature type="binding site" evidence="2">
        <location>
            <begin position="1426"/>
            <end position="1433"/>
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        <ligand>
            <name>ATP</name>
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            <position position="247"/>
        </location>
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            <position position="489"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="4">
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            <position position="545"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="4">
        <location>
            <position position="956"/>
        </location>
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    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="4">
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            <position position="1097"/>
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        <location>
            <position position="1552"/>
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        <source>
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    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00498"/>
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        <source>
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        </source>
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        <source>
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        </source>
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    <sequence length="1683" mass="186100" checksum="490B5CDCAEF7D7F0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4N323</accession>
    <name>G4N323_PYRO7</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">MGG_07655</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA51782.1"/>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA51782.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA51994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA51994.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Ma L.J."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_05091"/>
    <dbReference type="eggNOG" id="ENOG502TGYX">
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="214" mass="21170" checksum="894693AF48AF3DCC" modified="2011-12-14" version="1">MRYFTSFIILAASLAAAAPVPAPLPLPEPQNDRANNGATAIEAAVDIAFATALGQAGVFGQSSGPEFEAAQNQAARAAAQVAADALAANQAQGIQTELELDPPVQAALDEILGNNNGNNNNNGGNNNNNGGNNGGNNNGGGNNNGGNNNNGNNNGQNNNNGGNDNNNNNNNNNNNGGNNGNGNGGGFGGFRGFGGFGGGFGGGFGGFRRGRGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4J4</accession>
    <name>G4N4J4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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    <organism evidence="1 2">
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="PubMed" id="15846337"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711816.1">
        <property type="nucleotide sequence ID" value="XM_003711768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4J4"/>
    <dbReference type="GeneID" id="12984221"/>
    <dbReference type="KEGG" id="mgr:MGG_16727"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16727"/>
    <dbReference type="HOGENOM" id="CLU_2237125_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4J4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="105" mass="11833" checksum="8ED3199812BFB7F7" modified="2011-12-14" version="1">MRNCLVFVIFNRFVLPCIEIWVLFHGSIKFQGGIPELPVAQAEGYCHLGEVRAHRASTQVLLCEKQAYQGETGSTAFKSRPVNAELCLKKALIVVMYYAPFQNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4S6</accession>
    <name>G4N4S6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hsp70-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712698.1">
        <property type="nucleotide sequence ID" value="XM_003712650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4S6"/>
    <dbReference type="SMR" id="G4N4S6"/>
    <dbReference type="STRING" id="242507.G4N4S6"/>
    <dbReference type="GeneID" id="2675607"/>
    <dbReference type="KEGG" id="mgr:MGG_05163"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05163"/>
    <dbReference type="eggNOG" id="KOG0101">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009958_6_5_1"/>
    <dbReference type="InParanoid" id="G4N4S6"/>
    <dbReference type="OMA" id="KRCRRHY"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF81">
        <property type="entry name" value="HSP70 FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14040)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="618" mass="68292" checksum="50BAE4330B1A5018" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5A4</accession>
    <name>G4N5A4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-galactose transporter homolog 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_16886</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712768.1">
        <property type="nucleotide sequence ID" value="XM_003712720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5A4"/>
    <dbReference type="FunCoup" id="G4N5A4">
        <property type="interactions" value="473"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5A4"/>
    <dbReference type="GeneID" id="12985186"/>
    <dbReference type="KEGG" id="mgr:MGG_16886"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16886"/>
    <dbReference type="eggNOG" id="KOG1581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036019_0_2_1"/>
    <dbReference type="InParanoid" id="G4N5A4"/>
    <dbReference type="OMA" id="CGAIGQV"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005459">
        <property type="term" value="F:UDP-galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005460">
        <property type="term" value="F:UDP-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA52961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="420" mass="45299" checksum="1F8E347F558C879E" modified="2011-12-14" version="1">MARTKRTAVQREPSSEYISKADRPAQRGDDLAAPKSEDAALPAKADAPLPPIVPRDVGLTQLVISVAGIYGSFLTWAYLQEKLTTTNYGPPGSPPEVFKFPVFLNTIQSIFAAATGFVYLITSTPRGRPVPPIIPSRAILGPLLLVALTTALASPFGYASLAHIDYITFLLAKSCKLLPVMFLHITLFRKRYPMYKYLVVAAVTAGVAVFTLHSGSNKKKSAGRPSSGQTSWGLLLLSINLLFDGLTNSTQDYIFTAFRPYTGPQMMCANNMMSTIVTGLYLLLSPYLVQTGLGSWLGMDVVAGSGAGELQSALAFMRRYPSVWRDVLGFAACGAVGQVFIFYTLATFSSVLLVTVTVTRKMFTMILSVIAFGHRLTQMQWLGVGLVFGGIGVEAAIARQEKMAKEAAKKKAGGGEKKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N612</accession>
    <name>G4N612_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716907.1">
        <property type="nucleotide sequence ID" value="XM_003716859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N612"/>
    <dbReference type="SMR" id="G4N612"/>
    <dbReference type="STRING" id="242507.G4N612"/>
    <dbReference type="GeneID" id="2684775"/>
    <dbReference type="KEGG" id="mgr:MGG_06620"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06620"/>
    <dbReference type="eggNOG" id="ENOG502SIEM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099938_0_0_1"/>
    <dbReference type="InParanoid" id="G4N612"/>
    <dbReference type="OMA" id="IRVEPIT"/>
    <dbReference type="OrthoDB" id="2832510at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF14">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="113"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="257" mass="28596" checksum="00AC2084B7509EC5" modified="2011-12-14" version="1">MSTSGFSFTVSLCETKEDLIQGHRIAIETFGRQTNDRIWQGFNPGWDTPEGEAAGARRLVERWEKSQAADQKDQQGRPFVVFLKATAPDPADGKPVVAGLAIWVQASAVEGKGAVPVLDVAEAQDLNELWPGNDTEHQYLRQAEKGLHRRRNEVIREKATEDPPAVFALDMCVVDPRFQRRGISQSLVKWGIEEAKARNGLECVTEASSMGRGSYAKLGFKWEGEEPVDSDYGFDDRFKDRPAPPNLFMRTGSLTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N677</accession>
    <name>G4N677_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716120.1">
        <property type="nucleotide sequence ID" value="XM_003716072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N677"/>
    <dbReference type="GeneID" id="12984328"/>
    <dbReference type="KEGG" id="mgr:MGG_17047"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17047"/>
    <dbReference type="HOGENOM" id="CLU_3032850_0_0_1"/>
    <dbReference type="InParanoid" id="G4N677"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="55" mass="5932" checksum="A3CBD67657BC9E3F" modified="2011-12-14" version="1">MGEKPSDFQFYCGTAAEQPGRTTDGSGNQRTTNPSSQVGEALIASQLFYRGTELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6D9</accession>
    <name>G4N6D9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716980.1">
        <property type="nucleotide sequence ID" value="XM_003716932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6D9"/>
    <dbReference type="GeneID" id="12985523"/>
    <dbReference type="KEGG" id="mgr:MGG_17168"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17168"/>
    <dbReference type="HOGENOM" id="CLU_2498291_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6D9"/>
    <dbReference type="OrthoDB" id="10500449at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="86" mass="9574" checksum="023F2BFA893F56FC" modified="2011-12-14" version="1">MHPLAECRATILDGGRGGLQGIILRHSREVVPADNDRPLKSGNGCGKKERFLSPLRKTGDLCYTNWSQPPVPVQFQMHKEYSQGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6H9</accession>
    <name>G4N6H9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Inner membrane transporter yfaV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03713</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716168.1">
        <property type="nucleotide sequence ID" value="XM_003716120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6H9"/>
    <dbReference type="SMR" id="G4N6H9"/>
    <dbReference type="GeneID" id="2676540"/>
    <dbReference type="KEGG" id="mgr:MGG_03713"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03713"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="InParanoid" id="G4N6H9"/>
    <dbReference type="OMA" id="SYTMPTI"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF54">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="58"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA49849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="510" mass="56278" checksum="3B8BBCAF5296F0CC" modified="2011-12-14" version="1">MATQDNRKSGDVEHDKPGVKTQEYAGSNCGLTPEDREFMSRYEGKAGKAIVRKIDVRLIPIMGILYLLAHIDRGNIGNAKIEGIDQELGLVGNQYNIASTIFFVPYIIFEIPSNIILKKVRPSIWLSLLIMAWGITMTCMGFVKNFDGLVATRVVLGIFEAGFFPGAVYIVSSWYPRHELQQRLALFYTASAFSGALSGLLSYGIARMDGARGISGWRWIFLIEGAITVAAGIAMPFLVIDTPEHAKWLSDDEKRFIDLRLRLSGVRSNTEEGDKFSCKLLFSTMIDWKIALGILLAWANSVPNAAFKFTMPQIIKQLGFSTVNAQLLTMPPYVCGGISAWLVGRFADKFRWRMPFIVGPMTVLAVALGVLFGYSDKVTTSVPAMYVGVVLAQVGIYPLLPGISAWVGNNLAPSWKRSIGLAWLLAAGNLGSLVGTNIFLDQEAPRYPTGYGTALGIICLGLIAAFALEFFLWKMNKRKARLSESAIRAEYTQDHLDCMGEKSPLYIYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7A4</accession>
    <name>G4N7A4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717133.1">
        <property type="nucleotide sequence ID" value="XM_003717085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7A4"/>
    <dbReference type="SMR" id="G4N7A4"/>
    <dbReference type="STRING" id="242507.G4N7A4"/>
    <dbReference type="GeneID" id="2684591"/>
    <dbReference type="KEGG" id="mgr:MGG_06436"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06436"/>
    <dbReference type="eggNOG" id="ENOG502QQZ5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048607_2_1_1"/>
    <dbReference type="InParanoid" id="G4N7A4"/>
    <dbReference type="OMA" id="WFYLEEK"/>
    <dbReference type="OrthoDB" id="342264at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="13"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="275" mass="32068" checksum="AB808FE8DB6F2F59" modified="2011-12-14" version="1">MSKPARTKKMEPWEKPVFRGCKIAIAGQLDENWTEPQIERWIKYRHGQLVDKVDDTVTHLVCSKEEFDKGGTGIFGRVADAYRIMKAKNKGKRGSKNLHKIFIVKSDWLEFSCLKAKKLRELDYEWNRPEKKESQKAVQEKRLAKGKQLEEDGFVNTELNHVYTDSTSFKYEITLEGKDSSCYTLYLFESNATPRLYHFVAKFIKKKRSPPNYHRPSATQGLFPREFDLLKAFFRSKTGVEWEDRLRDYLVPKDAKFTYTPPVGNAPKGSKEELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7L8</accession>
    <name>G4N7L8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATPase family AAA domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_06380</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA50875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717194.1">
        <property type="nucleotide sequence ID" value="XM_003717146.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N7L8"/>
    <dbReference type="FunCoup" id="G4N7L8">
        <property type="interactions" value="713"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N7L8"/>
    <dbReference type="GeneID" id="2684535"/>
    <dbReference type="KEGG" id="mgr:MGG_06380"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06380"/>
    <dbReference type="eggNOG" id="KOG0732">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000536_1_2_1"/>
    <dbReference type="InParanoid" id="G4N7L8"/>
    <dbReference type="OMA" id="VTPKDFM"/>
    <dbReference type="OrthoDB" id="5421at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0006337">
        <property type="term" value="P:nucleosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0045815">
        <property type="term" value="P:transcription initiation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Bromo_TBP7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA family ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000061">
        <property type="entry name" value="ATPase family, AAA domain-containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045199">
        <property type="entry name" value="ATAD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069:SF0">
        <property type="entry name" value="TAT-BINDING HOMOLOG 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="653"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="955"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1363"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1532"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1686"/>
            <end position="1706"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1294"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
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            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
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            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
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            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
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            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
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            <end position="419"/>
        </location>
    </feature>
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        <location>
            <begin position="425"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1365"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
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        </location>
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    </feature>
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        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA50875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1706" mass="186969" checksum="7533B682F17B1382" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8G1</accession>
    <name>G4N8G1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MaoC-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_06264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717328.1">
        <property type="nucleotide sequence ID" value="XM_003717280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8G1"/>
    <dbReference type="SMR" id="G4N8G1"/>
    <dbReference type="FunCoup" id="G4N8G1">
        <property type="interactions" value="38"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N8G1"/>
    <dbReference type="GeneID" id="2684419"/>
    <dbReference type="KEGG" id="mgr:MGG_06264"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06264"/>
    <dbReference type="eggNOG" id="ENOG502S5QU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028690_1_0_1"/>
    <dbReference type="InParanoid" id="G4N8G1"/>
    <dbReference type="OMA" id="YPHEAAH"/>
    <dbReference type="OrthoDB" id="3257538at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052741">
        <property type="entry name" value="Mitochondrial_HTD2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152:SF1">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="34057" checksum="C3960303EEEB89B2" modified="2011-12-14" version="1">MLAESELLPDGTDPKHSPGQGFSRQPAREHKAVISADKLRLGSLRCACRESIADVTVRGQPGNEKVYVELLREYGYFHSVDLQRRETFRLSIIERRTLVFLRDEEVKMDVAKSQDQTTASSSDSNSGNNKKVRAPAPHKPDYSFELTPSRRLLFHFSALTHNAHLIHLDREYCRASEGHRDLLVHGPLSLVLMLTALRAAAKVVGPARAEKHIQSISYRNLAPLYVGETMRVCVRHTSNAATEYPATGTKRSTDSWEIWIEGPDGGMAVKASAVTMSGPKKYKANLKKNRAGDHENNVSPGNQEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8G9</accession>
    <name>G4N8G9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717336.1">
        <property type="nucleotide sequence ID" value="XM_003717288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8G9"/>
    <dbReference type="GeneID" id="12985645"/>
    <dbReference type="KEGG" id="mgr:MGG_17204"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17204"/>
    <dbReference type="HOGENOM" id="CLU_1986848_0_0_1"/>
    <dbReference type="InParanoid" id="G4N8G9"/>
    <dbReference type="OMA" id="QWFTEEN"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="126" mass="14393" checksum="90A9C8EF9A1451AB" modified="2011-12-14" version="1" fragment="single">SLCCLPVQIQRHALTDSSAHGQQRQNVTPVPSRHPQNGPVTSTRRFFVNGSYELNTPQNTATKLRIRQWFTEENLRKPSEQPEWLTKMGVLNHAQHGRRQIAPERSQPGLNRANRGDRVGNPRRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8K7</accession>
    <name>G4N8K7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_03418</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716520.1">
        <property type="nucleotide sequence ID" value="XM_003716472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N8K7"/>
    <dbReference type="SMR" id="G4N8K7"/>
    <dbReference type="STRING" id="242507.G4N8K7"/>
    <dbReference type="GeneID" id="2676979"/>
    <dbReference type="KEGG" id="mgr:MGG_03418"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03418"/>
    <dbReference type="eggNOG" id="KOG0137">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0537">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_4_4_1"/>
    <dbReference type="InParanoid" id="G4N8K7"/>
    <dbReference type="OMA" id="YQCEKMG"/>
    <dbReference type="OrthoDB" id="10254877at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF28">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="540" mass="60335" checksum="4E06557315B0577D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9D3</accession>
    <name>G4N9D3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_10011</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717493.1">
        <property type="nucleotide sequence ID" value="XM_003717445.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4N9D3"/>
    <dbReference type="STRING" id="242507.G4N9D3"/>
    <dbReference type="GeneID" id="2680968"/>
    <dbReference type="KEGG" id="mgr:MGG_10011"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10011"/>
    <dbReference type="eggNOG" id="KOG1178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1202">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_6_2_1"/>
    <dbReference type="InParanoid" id="G4N9D3"/>
    <dbReference type="OMA" id="FRINTMI"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF14">
        <property type="entry name" value="ITERATIVE POLYKETIDE SYNTHASE AFOE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="8">
        <location>
            <begin position="403"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="9">
        <location>
            <begin position="1342"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1752"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1342"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="5">
        <location>
            <begin position="1545"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1731"/>
            <end position="1752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1732"/>
            <end position="1743"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="5">
        <location>
            <position position="1375"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="5">
        <location>
            <position position="1606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA51174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="2307" mass="248747" checksum="AF9270D7E5AF0426" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N9E3</accession>
    <name>G4N9E3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717503.1">
        <property type="nucleotide sequence ID" value="XM_003717455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N9E3"/>
    <dbReference type="GeneID" id="2681027"/>
    <dbReference type="KEGG" id="mgr:MGG_10004"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10004"/>
    <dbReference type="HOGENOM" id="CLU_1886173_0_0_1"/>
    <dbReference type="InParanoid" id="G4N9E3"/>
    <dbReference type="OrthoDB" id="10464069at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466192" evidence="2">
        <location>
            <begin position="24"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="135" mass="14210" checksum="E43D01623E1D8B8D" modified="2011-12-14" version="1">MHFQTILAVASATILAFGSGAAARRVMVLPIQIYQGNNMILELKDQVAGGTAYASIHLRGQPRMQQYPIPISKTGNPDPSQLPPGYTAIANRAGARVVDLLPDGSVPGAGTGGARSPRSPRRRLTVPGVTDRLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAA6</accession>
    <name>G4NAA6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DDB1- and CUL4-associated factor 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">WD repeat and SOF domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_03210</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat DCAF13/WDSOF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716770.1">
        <property type="nucleotide sequence ID" value="XM_003716722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAA6"/>
    <dbReference type="SMR" id="G4NAA6"/>
    <dbReference type="FunCoup" id="G4NAA6">
        <property type="interactions" value="1254"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAA6"/>
    <dbReference type="GeneID" id="2676754"/>
    <dbReference type="KEGG" id="mgr:MGG_03210"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03210"/>
    <dbReference type="eggNOG" id="KOG0268">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033999_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAA6"/>
    <dbReference type="OMA" id="EDHNAYI"/>
    <dbReference type="OrthoDB" id="10249065at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001074">
        <property type="entry name" value="Probable SOF1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000657">
        <property type="entry name" value="U3 small nucleolar RNA associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007287">
        <property type="entry name" value="Sof1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051733">
        <property type="entry name" value="WD_repeat_DCAF13/WDSOF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851:SF0">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04158">
        <property type="entry name" value="Sof1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="60"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="266"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="309"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Sof1-like protein" evidence="11">
        <location>
            <begin position="342"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA50451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="445" mass="50781" checksum="705AA65696AEFFA6" modified="2011-12-14" version="1">MKIKALSRAPQQPAGSDVARKPKNVDPALHPFERAREYQRALNAVKMERMFAAPFIAQLGKGHVDSVFSMTVDPESLSRVASGSADGVVKIWDLTSREEMWHTTAHENIVKGMCFTKDQKLLTCASDRTIKLFSPDQASDSAPLSTWLGNNAFTSLSHHRSKNSFAAASSVISIYDLERHSAAPEVLRWPTSTDTINSVAFNQVEQSILGSYDLRTSMPLHKTVLNFTCNKFAWNPMEAFNFAVASEDHNIYLFDMRKIDRALNVLKGHVAAVMDVQFSPNGEELVSGSYDRTIRLWKRDKGHSADIYHTKRMQRVFASAWTPDNKYVLSGSDDGNVRLWRARASQREGVKSARQRQAEEYNQAVTARYAHMPEIRRIKNHRHVPKVIKKAGEIKSEELRAIKRREENERKHSSKKFEKRKAEREKMILAKEKKSKKILRLMFPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAT2</accession>
    <name>G4NAT2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Maintenance-ploidy protein mob1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716843.1">
        <property type="nucleotide sequence ID" value="XM_003716795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAT2"/>
    <dbReference type="SMR" id="G4NAT2"/>
    <dbReference type="FunCoup" id="G4NAT2">
        <property type="interactions" value="511"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAT2"/>
    <dbReference type="GeneID" id="2676737"/>
    <dbReference type="KEGG" id="mgr:MGG_03151"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03151"/>
    <dbReference type="eggNOG" id="KOG0440">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038321_3_2_1"/>
    <dbReference type="InParanoid" id="G4NAT2"/>
    <dbReference type="OMA" id="VDNEQMF"/>
    <dbReference type="OrthoDB" id="8170117at2759"/>
    <dbReference type="PHI-base" id="PHI:11084"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035974">
        <property type="term" value="C:meiotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071958">
        <property type="term" value="C:new mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071957">
        <property type="term" value="C:old mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902554">
        <property type="term" value="C:serine/threonine protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034973">
        <property type="term" value="C:Sid2-Mob1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903473">
        <property type="term" value="P:positive regulation of mitotic actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031031">
        <property type="term" value="P:positive regulation of septation initiation signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007096">
        <property type="term" value="P:regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="219" mass="25145" checksum="E3DC7816FB3EDD0A" modified="2011-12-14" version="1">MSAFLTTVNNRTRNQFRPRAAGKGGATSYQLRQYAEATLGGGSLRKVVKLPEGEDENEWLAVNMVDFYNQINLLYGAITEFCSPQTCPEMKATDEFEYLWQDNENFKRPTKMAAPAYIEQLMAWVQGSIDNEQVLPSRIGVPFPKTFPSLVRQIFKRMYRVYAHIYCHHYPVVRELGLEPHLNTSFKQYVLFIDEHSLASGKDYWGPLGDLVESMLKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAW0</accession>
    <name>G4NAW0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">(4-O-methyl)-D-glucuronate--lignin esterase</fullName>
            <ecNumber evidence="7">3.1.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03128</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O = 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67452"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:171667"/>
            <dbReference type="ChEBI" id="CHEBI:171668"/>
            <dbReference type="EC" id="3.1.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:67453"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate esterase 15 (CE15) family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.117" evidence="7"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716871.1">
        <property type="nucleotide sequence ID" value="XM_003716823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAW0"/>
    <dbReference type="SMR" id="G4NAW0"/>
    <dbReference type="STRING" id="242507.G4NAW0"/>
    <dbReference type="ESTHER" id="mago7-g4naw0">
        <property type="family name" value="Glucuronoyl_esterase"/>
    </dbReference>
    <dbReference type="GeneID" id="2676925"/>
    <dbReference type="KEGG" id="mgr:MGG_03128"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03128"/>
    <dbReference type="eggNOG" id="ENOG502QS8Y">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028869_1_1_1"/>
    <dbReference type="InParanoid" id="G4NAW0"/>
    <dbReference type="OMA" id="SHCQFPS"/>
    <dbReference type="OrthoDB" id="3781271at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046274">
        <property type="term" value="P:lignin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054579">
        <property type="entry name" value="GCE-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22244">
        <property type="entry name" value="GCE_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="4-O-methyl-glucuronoyl methylesterase-like" evidence="8">
        <location>
            <begin position="83"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA50552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="389" mass="40740" checksum="6D6B81E94ADCED60" modified="2011-12-14" version="1">MPASAIFSRQEATCSTPTNFPAVSERQLPDPWKMASGKSVASAEDWTCRQAEMSKALQQYVLGDYPPPPDSVTATSTATGLNIQIKVGSNTRAISVGITKPTNPGTSGGPAIIGIGGISIPVPAGIGRINFGNDACASQAGSQSHGTGWFFDLHGRSHSAGATTAWAWCVGRIIDALEQLGPAVTGINTARLGVSGCSRNGKGAFIVGALEKRIALTIPQESGSGGAACWRISDSEKAKGKNIQTASQIVTENAWFSPRFNSFTSRTTTIPADHHFLAAMVAPRGLFVIENDIDWLGPVSTTACMKAGRAIYQALGVGPSMGFSLVGGHQHCQFPSATTANLNSYINRFLLGTGQTNNVETSRATVNMAEWTSNWSAAPKITLTSPARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBW8</accession>
    <name>G4NBW8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Indoleamine 2,3-dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_14348</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717754.1">
        <property type="nucleotide sequence ID" value="XM_003717706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBW8"/>
    <dbReference type="SMR" id="G4NBW8"/>
    <dbReference type="FunCoup" id="G4NBW8">
        <property type="interactions" value="134"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NBW8"/>
    <dbReference type="GeneID" id="5048764"/>
    <dbReference type="KEGG" id="mgr:MGG_14348"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14348"/>
    <dbReference type="eggNOG" id="ENOG502QV6W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010089_0_1_1"/>
    <dbReference type="InParanoid" id="G4NBW8"/>
    <dbReference type="OMA" id="WHQYSGG"/>
    <dbReference type="OrthoDB" id="540174at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033754">
        <property type="term" value="F:indoleamine 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657:SF10">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00876">
        <property type="entry name" value="IDO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="439"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="4">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600898-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA48170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="55153" checksum="05B7F06C94DE4B06" modified="2011-12-14" version="1">MSPPEHTPQSPADLASWLESKYSVTPNGFLPSAEPLAVLPDAYYQPWETLASSLPKLLQTNSFRAHVDAELPVLSTSRLQAEQEWRRAYLILTFATHAYIWGGDKPSEHLPPQITVPLLDISRHLDLPPAATYAATNLWNFRTTAEGAPFSDLDAIESLITFTGTPDESWFYAVSVALECEGGNVIPAMISAMNAIPNNDLAACRQNIAALHKLMASIRRVGDILDRMHERCGPDVFYHAIRPFLAGSKNMADAGLPRGVLYDQGDGQGDWLGLRGGSNGQSSLIQFFDIVLGVEHKATENQNSDLKKREDQELPFHEEVRAYMPGPHRRFLEYVRSLPSIRDFALQPMETDEATGEQEDEEDHELMAERGLLRSTFTRATRVLAGLRNKHLQIVARYIILPSRRQQQQVRSGLGQQPGQRNIGLAGVAWREPPQNPVAVPNNDVDGAANGGGAGGGERKRRMSETQLTGTGGTALMPFLKQVRDETVRAGRPDEVAIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC11</accession>
    <name>G4NC11_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cell division control protein 42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_00466</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718598.1">
        <property type="nucleotide sequence ID" value="XM_003718550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC11"/>
    <dbReference type="SMR" id="G4NC11"/>
    <dbReference type="FunCoup" id="G4NC11">
        <property type="interactions" value="882"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NC11"/>
    <dbReference type="GeneID" id="2674265"/>
    <dbReference type="KEGG" id="mgr:MGG_00466"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00466"/>
    <dbReference type="eggNOG" id="KOG0393">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041217_21_3_1"/>
    <dbReference type="InParanoid" id="G4NC11"/>
    <dbReference type="OMA" id="GDEPYTF"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="PHI-base" id="PHI:2052"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01874">
        <property type="entry name" value="Cdc42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000236">
        <property type="entry name" value="Cell division control protein 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037874">
        <property type="entry name" value="Cdc42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 12" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA49014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="194" mass="21725" checksum="CA5BB6A0EA0C8406" modified="2011-12-14" version="1">MVVATIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVTSPASFENVREKWFPEVHHHCPGVPCLIVGTQVDLRDDPSVREKLSKQKMQPVRREDGERMAKELGAVKYVECSALTQYKLKDVFDEAIVAALEPPTPKRKSKKCLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC53</accession>
    <name>G4NC53_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717786.1">
        <property type="nucleotide sequence ID" value="XM_003717738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC53"/>
    <dbReference type="GeneID" id="12986630"/>
    <dbReference type="KEGG" id="mgr:MGG_17311"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17311"/>
    <dbReference type="HOGENOM" id="CLU_2758280_0_0_1"/>
    <dbReference type="InParanoid" id="G4NC53"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="70" mass="7335" checksum="50B8CD0F5D82CF17" modified="2011-12-14" version="1">MASRLFGQGLSSGDPGVHPKGWMMETPLGTAAARTVVLDRSPFGMEQTLQGSKGNTGLPPSLWGNDSPNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC89</accession>
    <name>G4NC89_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_01112</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SDE2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717822.1">
        <property type="nucleotide sequence ID" value="XM_003717774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC89"/>
    <dbReference type="SMR" id="G4NC89"/>
    <dbReference type="STRING" id="242507.G4NC89"/>
    <dbReference type="GeneID" id="2675056"/>
    <dbReference type="KEGG" id="mgr:MGG_01112"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01112"/>
    <dbReference type="eggNOG" id="KOG2827">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060603_0_0_1"/>
    <dbReference type="InParanoid" id="G4NC89"/>
    <dbReference type="OMA" id="RAPWIQN"/>
    <dbReference type="OrthoDB" id="547031at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051421">
        <property type="entry name" value="RNA_Proc_DNA_Dmg_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053822">
        <property type="entry name" value="SDE2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024974">
        <property type="entry name" value="Sde2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786">
        <property type="entry name" value="SPLICING FACTOR SF3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786:SF1">
        <property type="entry name" value="SPLICING REGULATOR SDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22782">
        <property type="entry name" value="SDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13019">
        <property type="entry name" value="Sde2_N_Ubi_yeast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sde2 ubiquitin" evidence="10">
        <location>
            <begin position="5"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="SDE2-like" evidence="11">
        <location>
            <begin position="89"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="98"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="205"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="208"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA48238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="298" mass="32520" checksum="A9A1B521EB1FF1D7" modified="2011-12-14" version="1">MTETINILISTFPGLGAPSTVSFPIESTSSASEIWDQLERRVALPNQRLFLTTHTNKNISSTSTQRVRSLLPDPSNDFLSLRLSAPLCGGKGGFGSQLRAAGGRMSSKKKSNGDNNGSSRNLDGRRVRTANEAKALAEYLAIKPDMEKKEKEKRRKRWEEIVEMTEKKEHEIKYGGKGRLDGKWVEDKEEAGERTRDAVLAALKAGNITDNMMVTPGSSSKAARVPLEEASSDEDMAEGDESESSAPTSPPSEPEKVDKGKGKEKAPAQTKAPAQSMKFSGFDDDDEFMSSSDEDESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCV8</accession>
    <name>G4NCV8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GPI anchored serine-threonine rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717935.1">
        <property type="nucleotide sequence ID" value="XM_003717887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NCV8"/>
    <dbReference type="GeneID" id="2674203"/>
    <dbReference type="KEGG" id="mgr:MGG_01009"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01009"/>
    <dbReference type="eggNOG" id="ENOG502SEV8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104756_0_0_1"/>
    <dbReference type="InParanoid" id="G4NCV8"/>
    <dbReference type="OMA" id="YCNAAKA"/>
    <dbReference type="OrthoDB" id="2507140at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466362" description="GPI anchored serine-threonine rich protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="15298" checksum="CA41BBEC6E4EE03C" modified="2011-12-14" version="1">MKSSFVLPFALLAATVAAQDPSCGATYIVDACLTGEKAKFNACEDKDWGCKCASYEAIVTCFNNCPNDPRKTSEEGQKSIFCGYNSQFPSSTTTASIAAATGASTTAAAATTSSSSTGSSTAAQPSQTGAAADLVMNAGGILAVVAAVVVAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>G4NCW2</accession>
    <name>G4NCW2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tctex-1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2018" name="Sci. Rep." volume="8" first="3952" last="3952">
            <title>Structure based function-annotation of hypothetical protein MGG_01005 from Magnaporthe oryzae reveals it is the dynein light chain orthologue of dynlt1/3.</title>
            <authorList>
                <person name="Li G."/>
                <person name="Huang J."/>
                <person name="Yang J."/>
                <person name="He D."/>
                <person name="Wang C."/>
                <person name="Qi X."/>
                <person name="Taylor I.A."/>
                <person name="Liu J."/>
                <person name="Peng Y.L."/>
            </authorList>
            <dbReference type="PubMed" id="29500373"/>
            <dbReference type="DOI" id="10.1038/s41598-018-21667-5"/>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (1.97 ANGSTROMS)</scope>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717939.1">
        <property type="nucleotide sequence ID" value="XM_003717891.1"/>
    </dbReference>
    <dbReference type="PDB" id="5HXL">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.97 A"/>
        <property type="chains" value="A=1-153"/>
    </dbReference>
    <dbReference type="PDB" id="5HYC">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="2.40 A"/>
        <property type="chains" value="A/B=1-153"/>
    </dbReference>
    <dbReference type="PDBsum" id="5HXL"/>
    <dbReference type="PDBsum" id="5HYC"/>
    <dbReference type="AlphaFoldDB" id="G4NCW2"/>
    <dbReference type="SMR" id="G4NCW2"/>
    <dbReference type="STRING" id="242507.G4NCW2"/>
    <dbReference type="GeneID" id="2675177"/>
    <dbReference type="KEGG" id="mgr:MGG_01005"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01005"/>
    <dbReference type="eggNOG" id="KOG4081">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_109453_1_0_1"/>
    <dbReference type="InParanoid" id="G4NCW2"/>
    <dbReference type="OMA" id="YKFACNS"/>
    <dbReference type="OrthoDB" id="10059120at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21456">
        <property type="entry name" value="DLC-like_SpDlc1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF4">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword evidence="4 5" id="KW-0002">3D-structure</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="4">
        <source>
            <dbReference type="PDB" id="5HXL"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="5">
        <source>
            <dbReference type="PDB" id="5HYC"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="16471" checksum="CEE3C902BFCBF41C" modified="2011-12-14" version="1">MAAQGPSPIPTNRLKQIAADACNDAIGSAEFYDHAKTEQWNHQIINTILKAVIAESQPSDSTTPPQFKFAVNSTIVQHLVPSSKLNKPAGGADDKPASTATSTDGKPHVGRRGMHSATGAFWNDKTDGMWTYKHEGDESKGMDVVVMLIWIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND81</accession>
    <name>G4ND81_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003718755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND81"/>
    <dbReference type="GeneID" id="12985003"/>
    <dbReference type="KEGG" id="mgr:MGG_17482"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17482"/>
    <dbReference type="InParanoid" id="G4ND81"/>
    <dbReference type="OrthoDB" id="5404599at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="108" mass="11821" checksum="BDD24BFA75715AE5" modified="2011-12-14" version="1" fragment="single">ELQQLSVCEQLGAMVKVWRCLIPDTAPVNTGGVCNRPVNKILRLHPALAGPFHEQNAVQEFQNGCGVKLDSSLMVAFFTRANLHPLNIILSPEPYGRVTAIINWAQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND82</accession>
    <name>G4ND82_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718804.1">
        <property type="nucleotide sequence ID" value="XM_003718756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND82"/>
    <dbReference type="SMR" id="G4ND82"/>
    <dbReference type="GeneID" id="5049822"/>
    <dbReference type="KEGG" id="mgr:MGG_14705"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14705"/>
    <dbReference type="HOGENOM" id="CLU_3014653_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND82"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="56" mass="6169" checksum="6B7CEDE91B1E909E" modified="2011-12-14" version="1">MPPQPPRLKPPIKTFPDTNFPQRPNATTLPTPSEGRALNPKPGSQCRPPPVLIKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDA3</accession>
    <name>G4NDA3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA damage-responsive protein 48</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718825.1">
        <property type="nucleotide sequence ID" value="XM_003718777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDA3"/>
    <dbReference type="GeneID" id="2674579"/>
    <dbReference type="KEGG" id="mgr:MGG_00273"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00273"/>
    <dbReference type="eggNOG" id="ENOG502S9RM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100306_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDA3"/>
    <dbReference type="OMA" id="RGQYKNT"/>
    <dbReference type="OrthoDB" id="3050608at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40462">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40462:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="14438" checksum="A4EC068F350FB148" modified="2011-12-14" version="1">MDFLKNVTGDKDAAQKPTNEQQQTTNQAAGGGFMDKLSGFTGGEQKPTTETQESSSGGFMDKLNSMAGGGKESEKSEDALDKGIDWVQENVMGQGQQSNESAIEQAKDKQIAGFIRDQYKTTTGSDFPVKEKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDC6</accession>
    <name>G4NDC6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_11462</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717999.1">
        <property type="nucleotide sequence ID" value="XM_003717951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDC6"/>
    <dbReference type="STRING" id="242507.G4NDC6"/>
    <dbReference type="GeneID" id="5050621"/>
    <dbReference type="KEGG" id="mgr:MGG_11462"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11462"/>
    <dbReference type="eggNOG" id="ENOG502QR5D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076139_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDC6"/>
    <dbReference type="OMA" id="ECQVKGW"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="168"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA48415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="221" mass="23843" checksum="7CA3B9EFE9FC2D1E" modified="2011-12-14" version="1">MGVIFLKILKKKTPHLSAKQPKKDTKPTMAPLPDFSNRDRFPTFVTIPEAGAPASDGSQQPEEWYLLAHIKNDMTIAKPTLVVEDRDGSPFAVVFEGYGRDDLDLKARGLKKGNTIVLPRARRVPPADETKRGFVRVDKADAAAVKAVPGALERVLALGGVEEDATVCSACGGKGEAGAGLSRCVGCGRARYCGKECQVKGWNESHKVYCKIFKGLDVVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDG6</accession>
    <name>G4NDG6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_11471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718039.1">
        <property type="nucleotide sequence ID" value="XM_003717991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDG6"/>
    <dbReference type="GeneID" id="2674519"/>
    <dbReference type="KEGG" id="mgr:MGG_11471"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11471"/>
    <dbReference type="HOGENOM" id="CLU_1713635_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDG6"/>
    <dbReference type="OMA" id="YLGDIHC"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="153" mass="17246" checksum="D6B7068442A2D9C4" modified="2011-12-14" version="1">MKTAREVPFQVYFYETPGLAGAIRPLTHVNPNTTSAVDPPAVAPLQALSDPQRAPAHQPEACVTFSRCRLPAHPNLILEQDEFFVVYELTETDRTVIFGRYGGFWCFHNLVILGRVSIDYLGDIHCPTRMTFLSYGYQVDKASRRPDGVLRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDG8</accession>
    <name>G4NDG8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="4">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_00919</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="4"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718041.1">
        <property type="nucleotide sequence ID" value="XM_003717993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDG8"/>
    <dbReference type="SMR" id="G4NDG8"/>
    <dbReference type="FunCoup" id="G4NDG8">
        <property type="interactions" value="1071"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NDG8"/>
    <dbReference type="MEROPS" id="C26.957"/>
    <dbReference type="GeneID" id="2674458"/>
    <dbReference type="KEGG" id="mgr:MGG_00919"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00919"/>
    <dbReference type="eggNOG" id="KOG1622">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014340_0_5_1"/>
    <dbReference type="InParanoid" id="G4NDG8"/>
    <dbReference type="OMA" id="IWQSFAV"/>
    <dbReference type="OrthoDB" id="1724632at2759"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000002">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000848">
        <property type="entry name" value="PRK00074.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="8 16" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 16" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="17">
        <location>
            <begin position="212"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="240"/>
            <end position="246"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA48457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="543" mass="60272" checksum="86CF6B8BE1F30140" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDK9</accession>
    <name>G4NDK9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_00227</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718878.1">
        <property type="nucleotide sequence ID" value="XM_003718830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDK9"/>
    <dbReference type="SMR" id="G4NDK9"/>
    <dbReference type="STRING" id="242507.G4NDK9"/>
    <dbReference type="CAZy" id="CBM18">
        <property type="family name" value="Carbohydrate-Binding Module Family 18"/>
    </dbReference>
    <dbReference type="GeneID" id="2674134"/>
    <dbReference type="KEGG" id="mgr:MGG_00227"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00227"/>
    <dbReference type="eggNOG" id="ENOG502SQAP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_660692_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDK9"/>
    <dbReference type="OMA" id="CKTTTAN"/>
    <dbReference type="OrthoDB" id="5242494at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11618">
        <property type="entry name" value="ChtBD1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466844" description="Chitin-binding type-1 domain-containing protein" evidence="10">
        <location>
            <begin position="21"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="29"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="91"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="138"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA49294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="416" mass="41294" checksum="C5147A4BC88CFE76" modified="2011-12-14" version="1">MRNTLVNLSLLLTLASPVFGAAVSKISSDATCGKASGFTCQGSKWGNCCSQYSYCGSSDAYCGTGCQSGYGTCKTTTANPPPSPGPKVSQDATCGNGVTCQGSKWGNCCSSHGWCGSSKDYCGAGCQSLFGTCDGVSTSSTSRSATVGGSSTSSTLTTSRTTTSSTTSSSVTSLTTSSTTTTSGSSTSSTSVTTTTSSSSSSSSTSSSASSSSSSTSTSTSTTSTQGLPTVTVTTISDDATSTSASSSTPSSTQTASSTASSSSTATSSSAPSATASTVRQYTQVFSHFPGCSYRGLATGISIPVSNLGPSGDYRAAAVPACQAYCDSSPGCQMFFIAVQQDSSIAPPNDVSATCQVSTAPFTTALAFCGFVSVGLWESYAYNLVETGPATVTASPTVSTGTSTSFIPITTIVDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="64" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDR2</accession>
    <name>G4NDR2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_11475</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718084.1">
        <property type="nucleotide sequence ID" value="XM_003718036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDR2"/>
    <dbReference type="SMR" id="G4NDR2"/>
    <dbReference type="STRING" id="242507.G4NDR2"/>
    <dbReference type="GeneID" id="5050635"/>
    <dbReference type="KEGG" id="mgr:MGG_11475"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11475"/>
    <dbReference type="eggNOG" id="KOG2204">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003818_1_0_1"/>
    <dbReference type="InParanoid" id="G4NDR2"/>
    <dbReference type="OMA" id="WDCVPQG"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF103">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSIDASE MNL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466491" description="alpha-1,2-Mannosidase" evidence="11">
        <location>
            <begin position="28"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="47"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="439"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="731"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="515"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="731"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="792"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="819"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="832"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="557"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="676"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="930"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="1016"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="633"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA48500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1028" mass="113215" checksum="B9E986C45F0D0EBB" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDT4</accession>
    <name>G4NDT4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cerato-platanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718900.1">
        <property type="nucleotide sequence ID" value="XM_003718852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDT4"/>
    <dbReference type="STRING" id="242507.G4NDT4"/>
    <dbReference type="GeneID" id="2674563"/>
    <dbReference type="KEGG" id="mgr:MGG_00210"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00210"/>
    <dbReference type="eggNOG" id="ENOG502SHQD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083928_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDT4"/>
    <dbReference type="OMA" id="DQSQGAH"/>
    <dbReference type="OrthoDB" id="5370830at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38850">
        <property type="entry name" value="CERATO-PLATANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38850:SF2">
        <property type="entry name" value="CERATO-PLATANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466155" description="Cerato-platanin" evidence="1">
        <location>
            <begin position="23"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="29468" checksum="1E9ECA168C01E11F" modified="2011-12-14" version="1">MRRPALLSPRSLITTICTTTAAFFSTTATALTEGTVWATPHSQYSSSVGVLGCKVNTNRIAYWPGVVDCDKICISLSYESRSVNLLRVDTSEGAYDVSYDAWNYLITGEGARQKPTAGGAVAMEYREAPADACKSLIHTPGNKLPLSASNSMNFLASCLEQPNSWVAKNYVLYNVLDPICSWGNDETCTLNWPTENQAKCKSGLGTPSVLSNQPVYNIEYPTGKTVLASNGSVVESPPDDNAATINQSPGRSAIVFALFATASTWLFPTILDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE94</accession>
    <name>G4NE94_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine protease</fullName>
            <ecNumber evidence="6">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00822</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S1B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="6"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718161.1">
        <property type="nucleotide sequence ID" value="XM_003718113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE94"/>
    <dbReference type="SMR" id="G4NE94"/>
    <dbReference type="GeneID" id="2674233"/>
    <dbReference type="KEGG" id="mgr:MGG_00822"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00822"/>
    <dbReference type="eggNOG" id="ENOG502SCHB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068119_1_0_1"/>
    <dbReference type="InParanoid" id="G4NE94"/>
    <dbReference type="OMA" id="HLMTARH"/>
    <dbReference type="OrthoDB" id="10037376at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050966">
        <property type="entry name" value="Glutamyl_endopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008256">
        <property type="entry name" value="Peptidase_S1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462:SF8">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00839">
        <property type="entry name" value="V8PROTEASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006991562" description="Serine protease" evidence="6">
        <location>
            <begin position="18"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="82"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA48577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="303" mass="32910" checksum="38B27611FABE76DD" modified="2011-12-14" version="1">MHMPWLSSILLAASCSAAMVPRDAAQAEQFRTLIGHDLPTVESFARIPLPEVRVMTAEEIVDWGGAATDAPPGNLTVERRDILGGVDDRVKKLDTGYPWSAMGRITILAPGRTTWCSGSLVGPRHLLTARHCILDGAAFVFSPAYASGDRLRTTYATHVLHLPGKEKQPTGWCDFSEDWAILRLNDDLGYGYLGYKLVEDAMSGADLDWWTYGYPQDRDGGQVPYAQNRFKIKKVGTCNGDPATPLDSTADAFGGQSGSPVWIPESGGRYQYGVLVAITAQSTLISNGPALLNGIIATRRDWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEN6</accession>
    <name>G4NEN6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome b-245 heavychain subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_00750</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718250.1">
        <property type="nucleotide sequence ID" value="XM_003718202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEN6"/>
    <dbReference type="SMR" id="G4NEN6"/>
    <dbReference type="STRING" id="242507.G4NEN6"/>
    <dbReference type="GeneID" id="2674859"/>
    <dbReference type="KEGG" id="mgr:MGG_00750"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00750"/>
    <dbReference type="eggNOG" id="KOG0039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005646_3_0_1"/>
    <dbReference type="InParanoid" id="G4NEN6"/>
    <dbReference type="OMA" id="FTFAKEH"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000091">
        <property type="entry name" value="NADPH oxidase (NoxA), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000029">
        <property type="entry name" value="NADPH oxidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF39">
        <property type="entry name" value="FAD-BINDING FR-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="240"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA48666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="553" mass="63270" checksum="57290F600E90C407" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEQ2</accession>
    <name>G4NEQ2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_00080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="entry name" value="Znf_C2H2_sf"/>
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        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
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    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
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        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49518.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="50" mass="5190" checksum="E53E94A7EA24B87B" modified="2011-12-14" version="1">MRSGFLIAALCTAGAVADTELSSPKIARRSSLFAVAFQVLAAGLATRYES</sequence>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGI0</accession>
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        <submittedName>
            <fullName evidence="3">Cell wall glycosyl hydrolase YteR</fullName>
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    <organism evidence="3 4">
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Mitchell T.K."/>
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                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003719456.1"/>
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        <property type="family name" value="Glycoside Hydrolase Family 105"/>
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    <dbReference type="GeneID" id="2677558"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_04305"/>
    <dbReference type="eggNOG" id="ENOG502QV67">
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    <dbReference type="HOGENOM" id="CLU_038720_1_0_1"/>
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        <property type="component" value="Chromosome 6"/>
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    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052043">
        <property type="entry name" value="PolySaccharide_Degr_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886:SF9">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466510" evidence="2">
        <location>
            <begin position="17"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="380" mass="42796" checksum="4DFB7DB0F1334330" modified="2011-12-14" version="1">MKTIYLAALVLGLASASPQSNLARMADTFIRIGVRKVFYYNEATLYTAFEAAYNLTGNSTLVSWYRDQIDDAVVLPDGTIRDWRLDYYSLDDYRIGNNLLWWYQRTGDAKYRAAADTIRRQLDRHPRTPSGGFWHRAPVYKDQMWFDGIFIADSFYARWTALFDGGNATAWDDIARQFDNIESRTRNQTTGLLVHGYDEAKRAVWADPVTGAAPLVWGRAVGWYFLALTEVIPLIPAAHPGRERLVRYFVTLAEGLKKAQDRGSGGWWLVISEPYPGRDGNYLESSAAAMFTAGLLRGIKLGLLETNKFRCTADKAYQHLVERFVTEGEDGTITWEGIVQVGSLSGNGTYEYYISIPVVRNDARGGGAFMLASYEMATLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH90</accession>
    <name>G4NH90_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_03907</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719967.1">
        <property type="nucleotide sequence ID" value="XM_003719919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NH90"/>
    <dbReference type="SMR" id="G4NH90"/>
    <dbReference type="FunCoup" id="G4NH90">
        <property type="interactions" value="161"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NH90"/>
    <dbReference type="GeneID" id="2677201"/>
    <dbReference type="KEGG" id="mgr:MGG_03907"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03907"/>
    <dbReference type="eggNOG" id="KOG0714">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043579_1_0_1"/>
    <dbReference type="InParanoid" id="G4NH90"/>
    <dbReference type="OMA" id="ARSREHN"/>
    <dbReference type="OrthoDB" id="1507364at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000069">
        <property type="entry name" value="ER associated DnaJ chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051100">
        <property type="entry name" value="DnaJ_subfamily_B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015399">
        <property type="entry name" value="DUF1977_DnaJ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908:SF3">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09320">
        <property type="entry name" value="DUF1977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="51"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="364" mass="40207" checksum="81E04D774C5684A3" modified="2011-12-14" version="1">MSSAKATGANTSNSSSSGARSRDHNQGNQGRSFTPEQKEAVLRIRRCKPTAFYDILALTTKTCTDAEIKRAYRKQSLLTHPDKNGYEGADEAFKMVSRAFSVLGDKEKREKFDRFGTDPDSRFESARAQNPFSGFAQRNAGGGGGGGGGGGGFPGFAGGFEEEISPEEMFRRFFGGGGFGQFGGFDTGPQFVFNMGGGPGIRVHQFGGNRPRRRPRAEGEPDPDAGILSTLLGLLPILFLFIIPLISSIMSGGSSSMPDVVFDEPQAPFTHKVKIPEHNVHYFVRPTDWQQFKGNNHKIAQLNKHAHVTLVNTLTHRCNVERHREQQLREQAQGWFFQDPEKMKIADQFKKPACERLSKLATRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHI6</accession>
    <name>G4NHI6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720063.1">
        <property type="nucleotide sequence ID" value="XM_003720015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHI6"/>
    <dbReference type="GeneID" id="2677220"/>
    <dbReference type="KEGG" id="mgr:MGG_03829"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03829"/>
    <dbReference type="eggNOG" id="ENOG502SNCE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092028_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHI6"/>
    <dbReference type="OMA" id="VWILIEF"/>
    <dbReference type="OrthoDB" id="5185882at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="265" mass="30313" checksum="A755BF5C0FFFDF0D" modified="2011-12-14" version="1">MSYAYYDRLIAAFAADNGTLQRSSLTHSTIGMVQYFYYIYLTHADGIGPLPLWMHLFYLAHDTIWAYIMFQEAPRYDYHPYFTSMAKGLVVWSILEVYCIYRAIVYEKEGLFGQDAAVDHKGEDGDGNDDDNNGKTKNKTRNGKKPTVAMALMHSFIVFFTFFCLVLTIIYMVGRESFPHWTLLTKILACTGAGGTWLQRGTRRGTRMSLALLSVVDAITCFWPYSRWVLVWPEVFDNPAYYLTGVCCTLSSVFNVYVLTRLPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHU5</accession>
    <name>G4NHU5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Elongation factor 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Eukaryotic elongation factor 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">MGG_14971</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720172.1">
        <property type="nucleotide sequence ID" value="XM_003720124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHU5"/>
    <dbReference type="SMR" id="G4NHU5"/>
    <dbReference type="FunCoup" id="G4NHU5">
        <property type="interactions" value="665"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NHU5"/>
    <dbReference type="GeneID" id="12987207"/>
    <dbReference type="KEGG" id="mgr:MGG_14971"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14971"/>
    <dbReference type="eggNOG" id="KOG0062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1242">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002848_0_0_1"/>
    <dbReference type="InParanoid" id="G4NHU5"/>
    <dbReference type="OMA" id="VLSEAMW"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18626">
        <property type="entry name" value="CD_eEF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000076">
        <property type="entry name" value="Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.990:FF:000001">
        <property type="entry name" value="Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000193">
        <property type="entry name" value="Probable Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015688">
        <property type="entry name" value="eEF3_ABC2_chromodomain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040533">
        <property type="entry name" value="EF3_4HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047036">
        <property type="entry name" value="EF3_4HB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17947">
        <property type="entry name" value="4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 18" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="repeat" description="HEAT" evidence="15">
        <location>
            <begin position="97"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="17">
        <location>
            <begin position="436"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="17">
        <location>
            <begin position="679"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="986"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="1033"/>
            <end position="1044"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00050030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00050045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="EHA47805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1055" mass="117190" checksum="A95782B3C5FCAE67" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHW0</accession>
    <name>G4NHW0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_09417</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720187.1">
        <property type="nucleotide sequence ID" value="XM_003720139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHW0"/>
    <dbReference type="GeneID" id="2680419"/>
    <dbReference type="KEGG" id="mgr:MGG_09417"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09417"/>
    <dbReference type="eggNOG" id="ENOG502RMG3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090404_1_0_1"/>
    <dbReference type="InParanoid" id="G4NHW0"/>
    <dbReference type="OMA" id="EIGPRPW"/>
    <dbReference type="OrthoDB" id="73901at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF120">
        <property type="entry name" value="HIGH-AFFINITY COPPER TRANSPORTER CTRA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA47820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="137" mass="15016" checksum="5BAC7C8A226536EE" modified="2011-12-14" version="1">MMVFHASTTTPLYLSGWQPISAGQYAGTCIFLIVLGTFTRITLALKPVLEARRWRPASHAKSASTEHHEVRRGGISWLATVERALYDVLVAALGYLLMLAVMTMNIGYCISVLGGVFFGSLVAVVWTSEHDGDWLPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI31</accession>
    <name>G4NI31_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720258.1">
        <property type="nucleotide sequence ID" value="XM_003720210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI31"/>
    <dbReference type="GeneID" id="12987249"/>
    <dbReference type="KEGG" id="mgr:MGG_17798"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17798"/>
    <dbReference type="HOGENOM" id="CLU_1835545_0_0_1"/>
    <dbReference type="InParanoid" id="G4NI31"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA47891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="140" mass="14909" checksum="2506A6E94DFEC677" modified="2011-12-14" version="1">MSVQFTNVNDWISPRFTGLPSIAKQSRSRATGSSQVTGLPSPGSSGTEAEFPHVVFIANARMGHDSGGPYAYKGICPVKKKINGSYFQLHSPAGACPCYGTKSKMQPFEAIGGTNVFQSKIPVSFKVSVEKHDSLGQKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJ17</accession>
    <name>G4NJ17_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetraspanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12594</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720976.1">
        <property type="nucleotide sequence ID" value="XM_003720928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJ17"/>
    <dbReference type="SMR" id="G4NJ17"/>
    <dbReference type="STRING" id="242507.G4NJ17"/>
    <dbReference type="GeneID" id="5050474"/>
    <dbReference type="KEGG" id="mgr:MGG_12594"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12594"/>
    <dbReference type="eggNOG" id="ENOG502S3E8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066479_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJ17"/>
    <dbReference type="OMA" id="LGQCPLT"/>
    <dbReference type="OrthoDB" id="2279611at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="225" mass="24770" checksum="8FAE38EA94A9F5A8" modified="2011-12-14" version="1">MANKILVAYIFADFLFVLMGALMLGFSIVVGNVRDEVPTEGNQAARNLLYQKFPLTAGIVNAIFIFITFLLTIPALSTPARGWLKMSGYLVVVNALFSLVIGLFLWIMTLKTRDDLFPIWVQQTPQVQSLMEVSFKCCGYYNSTAPAFVTNQVCPSPAASALMRGCATPITSFANVFVDNIFTGVFGMCGIDGLLVIATACLLKDRKEQERFRHIDQKTGPMSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJA0</accession>
    <name>G4NJA0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721059.1">
        <property type="nucleotide sequence ID" value="XM_003721011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJA0"/>
    <dbReference type="GeneID" id="12984876"/>
    <dbReference type="KEGG" id="mgr:MGG_15015"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15015"/>
    <dbReference type="HOGENOM" id="CLU_2015736_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJA0"/>
    <dbReference type="OrthoDB" id="10338159at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA46316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="123" mass="13489" checksum="B437CFED67EA9AF0" modified="2011-12-14" version="1">MAIPPSFVTILSVRPFGQSTLAMAQSYLSIRPVQIRKTFRFDSQCDAHAHRSHPSLLLAVTLRRVPLANNAQFRHSMVNSVAVNPCSISAFTRAGEMDNATEANTDIVKASGRTVDDVKILHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKR9</accession>
    <name>G4NKR9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histidine kinase G7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_12530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720640.1">
        <property type="nucleotide sequence ID" value="XM_003720592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKR9"/>
    <dbReference type="SMR" id="G4NKR9"/>
    <dbReference type="STRING" id="242507.G4NKR9"/>
    <dbReference type="GeneID" id="5050414"/>
    <dbReference type="KEGG" id="mgr:MGG_12530"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12530"/>
    <dbReference type="eggNOG" id="KOG0519">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002763_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKR9"/>
    <dbReference type="OMA" id="CIHAGHT"/>
    <dbReference type="OrthoDB" id="303614at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF11">
        <property type="entry name" value="HISTIDINE KINASE_RESPONSE REGULATOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="589"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="1143"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="238"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="379"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1047"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1098"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="260"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1047"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="1198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA45897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1271" mass="138021" checksum="F45AC11FF7E31088" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLU0</accession>
    <name>G4NLU0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular serine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_12584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <strain evidence="3">70-15</strain>
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            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
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                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
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                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
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</entry>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15</strain>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720550.1">
        <property type="nucleotide sequence ID" value="XM_003720502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHJ0"/>
    <dbReference type="SMR" id="G5EHJ0"/>
    <dbReference type="FunCoup" id="G5EHJ0">
        <property type="interactions" value="18"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G5EHJ0"/>
    <dbReference type="GeneID" id="2681939"/>
    <dbReference type="KEGG" id="mgr:MGG_10287"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10287"/>
    <dbReference type="eggNOG" id="KOG0252">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_12_1"/>
    <dbReference type="OMA" id="EYTVCTS"/>
    <dbReference type="OrthoDB" id="2153661at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000140">
        <property type="entry name" value="Putative MFS phospholipid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="43"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EAQ71648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA45807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="491" mass="53172" checksum="7612D0F4652CF182" modified="2011-12-14" version="1">MTVAQEEAPKVVTVAESSETTKSSCSEDAVAPPPTQRPAGKFDVLIQGVALFSDGYNIQIIGYMNTVLAKLYPKEMTSEVKTRLSNSILIGDVFGMLLFGLCIDKFGRRVGIVLTTLFLVFGIILATASHGNTVEGMFWMMVVGRGVAGVGAGGEYTVCTSQALECADSTPEMRKRRGMLVAVSTNAAIISGFVGSSIVSLIVIAAYGSQASDGIWRICFGIGIFLPLTIFFFRMRLADSEQYQKHAIQHKVPYWLAIKFYWRALLGCCSAWFLYDFVVYPFNLLAPTLVAGFSSNQSMIESIGWSALINFFALPGSFIGALLMDRIGRRQTYALGWAIVCVFGFIIGGSMVQLQNIFPLFVVLYALFQTFLSVGPGDCNFLVSSESFPTPLRGHFLGFAAAVGKAGAAIGTTVLSQALASFDDKVKGQQAIFLIGSGISVVGTLCVWFLIPNAPKNLEDEDVRFRNYLQQNGYDTSDMGLQAKKVEGAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2006-03-07" modified="2026-01-28" version="98" xmlns="https://uniprot.org/uniprot">
    <accession>Q2KEK2</accession>
    <name>Q2KEK2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGCH7_ch7g1034</name>
        <name evidence="10" type="ORF">MGG_10268</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15</strain>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH165178">
        <property type="protein sequence ID" value="KYQ30514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846018.1">
        <property type="nucleotide sequence ID" value="XM_016990515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q2KEK2"/>
    <dbReference type="SMR" id="Q2KEK2"/>
    <dbReference type="FunCoup" id="Q2KEK2">
        <property type="interactions" value="176"/>
    </dbReference>
    <dbReference type="STRING" id="242507.Q2KEK2"/>
    <dbReference type="GeneID" id="2681821"/>
    <dbReference type="KEGG" id="mgr:MGG_10268"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10268"/>
    <dbReference type="eggNOG" id="KOG0581">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_79_2_1"/>
    <dbReference type="OMA" id="YICVEYM"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005934">
        <property type="term" value="C:cellular bud tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005078">
        <property type="term" value="F:MAP-kinase scaffold activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038066">
        <property type="term" value="P:p38MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016239">
        <property type="term" value="P:positive regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF25">
        <property type="entry name" value="MAP KINASE KINASE PBS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="299"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="116"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="646"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EAQ71627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KYQ30514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="685" mass="71799" checksum="902966449D16ED33" modified="2006-03-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4H8</accession>
    <name>A0A151V4H8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_12509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845979.1">
        <property type="nucleotide sequence ID" value="XM_016990539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4H8"/>
    <dbReference type="GeneID" id="5050395"/>
    <dbReference type="KEGG" id="mgr:MGG_12509"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12509"/>
    <dbReference type="InParanoid" id="A0A151V4H8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007589969" description="Secreted protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KYQ30475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="10753" checksum="EE6A6A786F251837" modified="2016-06-08" version="1">MPTLALACLAGLHGARACSHGPVVIHVLLAQGLDVDEPPTNRRRARTAHHQQLKDDGRPRSCGRANPGSRAASASGSRAGQSEAGWPEIEIMCFYKLSLKT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-01-15" modified="2025-06-18" version="102" xmlns="https://uniprot.org/uniprot">
    <accession>A4QXX4</accession>
    <accession>G4N9S7</accession>
    <name>SSN3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Serine/threonine-protein kinase SSN3</fullName>
            <ecNumber>2.7.11.22</ecNumber>
            <ecNumber>2.7.11.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Cyclin-dependent kinase 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">SSN3</name>
        <name type="synonym">CDK8</name>
        <name type="ORF">MGG_13931</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the SRB8-11 complex, a regulatory module of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22"/>
    <dbReference type="EC" id="2.7.11.23"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715904.1">
        <property type="nucleotide sequence ID" value="XM_003715856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4QXX4"/>
    <dbReference type="SMR" id="A4QXX4"/>
    <dbReference type="FunCoup" id="A4QXX4">
        <property type="interactions" value="1028"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4QXX4"/>
    <dbReference type="EnsemblFungi" id="MGG_13931T0">
        <property type="protein sequence ID" value="MGG_13931T0"/>
        <property type="gene ID" value="MGG_13931"/>
    </dbReference>
    <dbReference type="GeneID" id="5049253"/>
    <dbReference type="KEGG" id="mgr:MGG_13931"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13931"/>
    <dbReference type="eggNOG" id="KOG0666">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A4QXX4"/>
    <dbReference type="OMA" id="YFKNGGP"/>
    <dbReference type="OrthoDB" id="6284126at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990508">
        <property type="term" value="C:CKM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060258">
        <property type="term" value="P:negative regulation of filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070481">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, non-stop decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051094">
        <property type="term" value="P:positive regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031648">
        <property type="term" value="P:protein destabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000408">
        <property type="entry name" value="Serine/threonine-protein kinase SSN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000426">
        <property type="entry name" value="Serine/threonine-protein kinase ssn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0010">Activator</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0539">Nucleus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000312947" description="Serine/threonine-protein kinase SSN3">
        <location>
            <begin position="1"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="61"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="332"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="463"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2 3">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="67"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="499" mass="55094" checksum="4D6D22BA3A00FAA1" modified="2008-01-15" version="2">MSHSNPPTGASGGPGSASASAAPARGYYSLKRSIQTAFNDPLDRGLGPPAYQSKVRVMDKYQVIGFISSGTYGRVYKARGRQGQPGEFAIKKFKPDKEGEQITYTGISQSAIREMALCSELRHPNVIRLVETILEDKAIFMVFEYAEHDLLQIIHHHTQQPKHPIPPQTIKSIMFQLLNGCQYLHTNWVLHRDLKPANIMVTSSGEVKVGDLGLARIFWKPVRTLMQGDKVVVTIWYRAPELLMGSHHYTPAVDMWAVGCIFAELLSLRPIFKGEEAKMDNTKKGGSRDMPFQRHQMQKIVDIMGMPTKERWPLLTSMPDYDKLPLLQPPLSASGYSQQPAHSHHHHQHYNQGPQYGGRAGGPTSSSSANSSSAAAAASQSHLDKWYYHTVSQGQTAGPMPHAPPGSLASLGVEGYKLLAGLLEYDPEKRLTAAAALQHNFFSTGDRVSANCFEGCKAEYPHRRVSQEDNDIRTGSVPGTKRSGMPDDSMGRPGKRVKE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-05-31" modified="2025-04-09" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>A4RI88</accession>
    <accession>G4MUK3</accession>
    <name>RTC5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Restriction of telomere capping protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">RTC5</name>
        <name type="ORF">MGG_07277</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RTC5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715502.1">
        <property type="nucleotide sequence ID" value="XM_003715454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RI88"/>
    <dbReference type="SMR" id="A4RI88"/>
    <dbReference type="STRING" id="242507.A4RI88"/>
    <dbReference type="EnsemblFungi" id="MGG_07277T0">
        <property type="protein sequence ID" value="MGG_07277T0"/>
        <property type="gene ID" value="MGG_07277"/>
    </dbReference>
    <dbReference type="GeneID" id="2683023"/>
    <dbReference type="KEGG" id="mgr:MGG_07277"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07277"/>
    <dbReference type="eggNOG" id="ENOG502QV3R">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011918_1_0_1"/>
    <dbReference type="InParanoid" id="A4RI88"/>
    <dbReference type="OMA" id="KWEFEAR"/>
    <dbReference type="OrthoDB" id="289228at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF130">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000408830" description="Restriction of telomere capping protein 5">
        <location>
            <begin position="1"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="TLDc" evidence="2">
        <location>
            <begin position="342"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="307"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="406"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="629" mass="68791" checksum="4F1890643837AD87" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKR6</accession>
    <name>G4MKR6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709368.1">
        <property type="nucleotide sequence ID" value="XM_003709320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKR6"/>
    <dbReference type="GeneID" id="2684834"/>
    <dbReference type="KEGG" id="mgr:MGG_06661"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06661"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="InParanoid" id="G4MKR6"/>
    <dbReference type="OMA" id="VILDVWY"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000188">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF50">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00840)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
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            <begin position="292"/>
            <end position="311"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="390"/>
            <end position="410"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
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        <location>
            <begin position="66"/>
            <end position="481"/>
        </location>
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        </location>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA56756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="514" mass="57079" checksum="C7DFA1CF20FF142A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKV1</accession>
    <name>G4MKV1_PYRO7</name>
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        <recommendedName>
            <fullName evidence="3">Thioesterase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05357</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
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        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003710150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKV1"/>
    <dbReference type="SMR" id="G4MKV1"/>
    <dbReference type="GeneID" id="2676172"/>
    <dbReference type="KEGG" id="mgr:MGG_05357"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05357"/>
    <dbReference type="eggNOG" id="ENOG502S78C">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="5538558at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="4HBT"/>
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    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050563">
        <property type="entry name" value="4-hydroxybenzoyl-CoA_TE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793:SF39">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="EHA57586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="40546" checksum="1325DC5E4A52828E" modified="2011-12-14" version="1">MPPPLRWGSMPRCRLGMQVASANCRGMRFQSTACRGVQLRKTAPRQPASRLCVAGPSGRRPCTPLAVPVGADRHSPNCRALSSSSTSFSVKNDTRFNPGPGERQYLQNIPREDTNGRWYFQLRERIGKCIIFGLSEAQLARAVDLVAAMSAEWEKLVLHMDEYPTDHDGLRNFTVPWGDMDSFGHVNNVRYSRYAETCRVNWVTGFAHKDPSNAEEWRSLMTKQSIGLIMAEISIRFLSPVVYPDTLNAYHKVIKLPDGPGEGDAATRSSMTLGCVIMSKKQRRIVATVTEKLVFYDYRTEKKTDAPEFALEVLRRACSDAAGAKAEAAVRIRQFREAVERLEAESWKREDAVEDLGSAGGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKX1</accession>
    <name>G4MKX1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">MGG_15179</name>
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    <organism evidence="2 3">
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710218.1">
        <property type="nucleotide sequence ID" value="XM_003710170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKX1"/>
    <dbReference type="GeneID" id="12985378"/>
    <dbReference type="KEGG" id="mgr:MGG_15179"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15179"/>
    <dbReference type="HOGENOM" id="CLU_2146349_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKX1"/>
    <dbReference type="OrthoDB" id="10525935at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="112" mass="12869" checksum="FCCD040AECC2A9F9" modified="2011-12-14" version="1">MCRSRTRRSLGRGRKQQRFGDAGKLQQEPWRPEHQPLPRKASSREPIGLSLWPINRKRMRMSKMLPYKPMSRVPVCVAPALRFETESRRPRDGSHARGGDDGMSGNLSVDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLA5</accession>
    <name>G4MLA5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Isotrichodermin C-15 hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_05390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710247.1">
        <property type="nucleotide sequence ID" value="XM_003710199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLA5"/>
    <dbReference type="SMR" id="G4MLA5"/>
    <dbReference type="STRING" id="242507.G4MLA5"/>
    <dbReference type="GeneID" id="2676177"/>
    <dbReference type="KEGG" id="mgr:MGG_05390"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05390"/>
    <dbReference type="eggNOG" id="KOG0158">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_11_1"/>
    <dbReference type="InParanoid" id="G4MLA5"/>
    <dbReference type="OMA" id="YYSYHLG"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11058">
        <property type="entry name" value="CYP60B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF210">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ASQL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA57635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="498" mass="56648" checksum="0D8DEB158C00FEA5" modified="2011-12-14" version="1">MESLASLTRLILMIPVTCLVYAFYRVVYNVFFHPLRQYPGPWHRGASRLPYTISIFRGDVTFRVKALHDKYGKVVRITPDTLSYTDSQAWSDVYSLKKTGSSGNLPKDPKFYVAAPDTSTANDADHRRLRRVQAHAFSEKALTMQESFIQQHTDRYIKCLERAAQEADGVVDVVKWVNFLTTDLIGDLSFGETFGGLASGRLHPWLESVFTTLKTFTFIREFLRLPSWATRLAVACIPKHMLEHQRSAVAFGADAARARIERGSDKPDFMHYILRHEKDDEKGMSPDEIYMAAITFIVAGSETTATMISGTVYLLLQHPDVLHRLVSVIRTDFPAIDDMNLVNLQQHEYLNAVIKEGLRLYPPAADFLFRTSGGQSVVVAGRVVPPKTSLTMNLWAMYRDPTNFHRPLEFIPDRWLKDAPAEFDKDDRACFKPFSVGPRDCIGKNLAYAEMRLILAKMAWSLDLLSVEPDSQGWIEKQKIFGLWEKPPLNVKLAPRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLD9</accession>
    <name>G4MLD9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710281.1">
        <property type="nucleotide sequence ID" value="XM_003710233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLD9"/>
    <dbReference type="GeneID" id="12986269"/>
    <dbReference type="KEGG" id="mgr:MGG_16357"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16357"/>
    <dbReference type="HOGENOM" id="CLU_2483786_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLD9"/>
    <dbReference type="OrthoDB" id="10487995at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465345" description="Secreted protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9516" checksum="D7D46A00E664F953" modified="2011-12-14" version="1">MEGLHALFFSFFFLFLFYPGVIRLGGVEAVDAKITAAKTGRARPPVCPESRRQPEPDCLDTPRARSHKAQPVLSIPSCSSADADDTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLI7</accession>
    <name>G4MLI7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711120.1">
        <property type="nucleotide sequence ID" value="XM_003711072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLI7"/>
    <dbReference type="GeneID" id="12986919"/>
    <dbReference type="KEGG" id="mgr:MGG_16552"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16552"/>
    <dbReference type="HOGENOM" id="CLU_1310353_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLI7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="210" mass="23535" checksum="CA383163D23251A2" modified="2011-12-14" version="1">MGHQVEDEKSKSAEQKTRQDIPPCQNQPSYSIGGLETPPDSSSPKSKRSSRQPANAPNQSPTAKEPQDTYYVGRPQGLSDQATDKKPESTGQDTPYKNQPTYFVGRPEFLHDSPSTKSKRSNDKPAYPYVAPDKPEHPSKYKKPDVPAPQQPWEKDSEQLYVGHPAGWNGNAEPFGNVYHVKDGRVEKTEPYRPSDPKSKSKSKSKWWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLK7</accession>
    <name>G4MLK7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">G-protein coupled receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06738</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709452.1">
        <property type="nucleotide sequence ID" value="XM_003709404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLK7"/>
    <dbReference type="GeneID" id="2684911"/>
    <dbReference type="KEGG" id="mgr:MGG_06738"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06738"/>
    <dbReference type="eggNOG" id="ENOG502QWAA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024810_3_1_1"/>
    <dbReference type="InParanoid" id="G4MLK7"/>
    <dbReference type="OMA" id="RMEIPYL"/>
    <dbReference type="OrthoDB" id="18453at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13952">
        <property type="entry name" value="7tm_classB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF22">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05462">
        <property type="entry name" value="Dicty_CAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="22"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="8">
        <location>
            <begin position="36"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="264"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="430"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="465"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="499" mass="56176" checksum="292DD57151B16A72" modified="2011-12-14" version="1">MTHFKMSGTPIDAVRLDQLNQYSIIERVCSVLSLLGSVFIIATFCYSNMFHKPINRLVFFASFGNMMTNVGTLMARSYVGDTDGAGCQFQAFLIQMFLPADTLWTLAMAVNVYLTFYHKFDAVKLRKMEIPYLFICYGLPFVIALTYVFIQSPERGRMYGDATLWCWISPRWDIWRLTTFYGPIWLIILVTFFIYIRAGGEIYRKHQQLRNFHSSTRSHHEPEPLPPMDDPLVSSKTTEVSITSEAVMPAVPGAIDLAPLGRRASDNAQQAPPPIPGPAYSVQISSTGTNTNDRRPSHHPELTIQPTRATLTRTTTRIGAIQQRSRANQDATNAAWSYTKCALLFFTAMLVTWLPSSANRVYSVIHANQVNLTLEYMSAFVLPLQGFWNAVIYIVTSWKACKLVFHDIFLSRMPVTELIDYRSSIIRRRQQSSNNRQSQAAGAGTGVAGSSHSRKESGSAGRITPQPSDKNYENESMTDLASRPSLQEPGQERRPHRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLR7</accession>
    <name>G4MLR7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chalcone isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710307.1">
        <property type="nucleotide sequence ID" value="XM_003710259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLR7"/>
    <dbReference type="SMR" id="G4MLR7"/>
    <dbReference type="FunCoup" id="G4MLR7">
        <property type="interactions" value="128"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MLR7"/>
    <dbReference type="GeneID" id="2675939"/>
    <dbReference type="KEGG" id="mgr:MGG_05446"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05446"/>
    <dbReference type="eggNOG" id="ENOG502RGD3">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038840_1_0_1"/>
    <dbReference type="InParanoid" id="G4MLR7"/>
    <dbReference type="OMA" id="FMHLRDG"/>
    <dbReference type="OrthoDB" id="18193at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47284">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47284:SF3">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16035">
        <property type="entry name" value="Chalcone_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="Chalcone isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone isomerase" evidence="2">
        <location>
            <begin position="165"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="394" mass="43459" checksum="CD61B84BE4007E4A" modified="2011-12-14" version="1">MLRQPASRCLRALPRRQQLPQSRTIFSRRSRASPGRAREELNVQRLAQESHEYNQMRRTFLTAGAVAGIISFIYTAYKLKLAIDNKPAKLDSTLPPSDPLLDGSNRKVVLHDDQGRELVPTGNKTVEFFPRTIDLPTVSENRASSAPSDPLAPPIVVNPSTQQTTEYTLVGLGTRSVTFIGINVYVVGFYIATADIAALQSRLVKRVNPIATTLVAGEKGDLHKSLLDPVEGEAIWNELLRDGIPARSAFRILPVRDTDFHHLRDGFVRAIQARSDKLVDEAGSNAGGDLVKADKDAFGESMRAFRQLFNRGKVPKSKELLLTREDGGRLRVVYDDGKSREVIGTVDDERVSRALWLNYLAGKNVASEPARKSIADGVLEFVERPVGTVAAQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLX7</accession>
    <name>G4MLX7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16576</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711156.1">
        <property type="nucleotide sequence ID" value="XM_003711108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLX7"/>
    <dbReference type="GeneID" id="12986952"/>
    <dbReference type="KEGG" id="mgr:MGG_16576"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16576"/>
    <dbReference type="HOGENOM" id="CLU_1960000_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLX7"/>
    <dbReference type="OrthoDB" id="5243188at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA58544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="128" mass="14308" checksum="D1A8CB0BED31F7D5" modified="2011-12-14" version="1">MDDIIFDSNPDGAPAGLDERVAQLADPEWADNILVDDDVEQNSTPENTETFTESSQRFWRVDHSTGTYKYKVGKPGRIISQFNCPTYEHVTVTFQKWASPYAAKYTGGINFDLTGRTFHIASGVSPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLZ0</accession>
    <name>G4MLZ0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ent-kaurene synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_01949</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the terpene synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708691.1">
        <property type="nucleotide sequence ID" value="XM_003708643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLZ0"/>
    <dbReference type="SMR" id="G4MLZ0"/>
    <dbReference type="STRING" id="242507.G4MLZ0"/>
    <dbReference type="GeneID" id="2681164"/>
    <dbReference type="KEGG" id="mgr:MGG_01949"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01949"/>
    <dbReference type="eggNOG" id="ENOG502QQN6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005861_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLZ0"/>
    <dbReference type="OMA" id="WNISPYY"/>
    <dbReference type="OrthoDB" id="2343925at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010333">
        <property type="term" value="F:terpene synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016102">
        <property type="term" value="P:diterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017057">
        <property type="entry name" value="Ent-kaurene_synthase_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050148">
        <property type="entry name" value="Terpene_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31739:SF25">
        <property type="entry name" value="(E,E)-GERANYLLINALOOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31739">
        <property type="entry name" value="ENT-COPALYL DIPHOSPHATE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036498">
        <property type="entry name" value="Ent-kaurene_synthase_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="700"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="705"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA56079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="962" mass="106966" checksum="6D446E91BF99C1CC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLZ5</accession>
    <name>G4MLZ5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003708648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLZ5"/>
    <dbReference type="GeneID" id="12985653"/>
    <dbReference type="KEGG" id="mgr:MGG_15985"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15985"/>
    <dbReference type="HOGENOM" id="CLU_2121555_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLZ5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="114" mass="12413" checksum="1E9B7368065E67D0" modified="2011-12-14" version="1">MLDYARTSAPSAFSLLVLSQRLVLQTERHNLHDDFQRVARQTPWNTTSASSTSGSTVQQRPFLTLITASSSSQLCPDDLSDGPVLRIATLGARIASPAVTAVEILLCVLRKRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMP8</accession>
    <name>G4MMP8_PYRO7</name>
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            <fullName evidence="3">Uncharacterized protein</fullName>
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        <name evidence="3" type="ORF">MGG_16404</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710432.1">
        <property type="nucleotide sequence ID" value="XM_003710384.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMP8"/>
    <dbReference type="GeneID" id="12986336"/>
    <dbReference type="KEGG" id="mgr:MGG_16404"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16404"/>
    <dbReference type="HOGENOM" id="CLU_151422_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMP8"/>
    <dbReference type="OrthoDB" id="10534312at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <dbReference type="InterPro" id="IPR045634">
        <property type="entry name" value="DUF6413"/>
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    <dbReference type="Pfam" id="PF19951">
        <property type="entry name" value="DUF6413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="chain" id="PRO_5003465130" evidence="2">
        <location>
            <begin position="18"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="142" mass="14933" checksum="BCC6E849CC50B418" modified="2011-12-14" version="1">MHATFITFLIAPLVVLGASSVTVGFGSTGGRCCRDGVADPSNTCKNLGLNSYACSDHSSSAPNEPGPKFSDKPKGGCDQPEIHNFPTGRDVKTFVVGSTVNVRRSNGQHRGWIHRMRGMINCNKAQSRAGDSGEGALNGVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMU8</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13691</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003708790.1">
        <property type="nucleotide sequence ID" value="XM_003708742.1"/>
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    <dbReference type="AlphaFoldDB" id="G4MMU8"/>
    <dbReference type="GeneID" id="5049452"/>
    <dbReference type="KEGG" id="mgr:MGG_13691"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13691"/>
    <dbReference type="eggNOG" id="ENOG502S8DI">
        <property type="taxonomic scope" value="Eukaryota"/>
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    <dbReference type="HOGENOM" id="CLU_023124_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMU8"/>
    <dbReference type="OMA" id="FWKDRFQ"/>
    <dbReference type="OrthoDB" id="5374688at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="670" mass="74511" checksum="B4958AA874916BF6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMX1</accession>
    <name>G4MMX1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-dependent permease MDL2</fullName>
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    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_06878</name>
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    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709605.1">
        <property type="nucleotide sequence ID" value="XM_003709557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMX1"/>
    <dbReference type="SMR" id="G4MMX1"/>
    <dbReference type="FunCoup" id="G4MMX1">
        <property type="interactions" value="468"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MMX1"/>
    <dbReference type="GeneID" id="2685051"/>
    <dbReference type="KEGG" id="mgr:MGG_06878"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06878"/>
    <dbReference type="eggNOG" id="KOG0058">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_3_1"/>
    <dbReference type="InParanoid" id="G4MMX1"/>
    <dbReference type="OMA" id="MYTGHTL"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18573">
        <property type="entry name" value="ABC_6TM_ABCB10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000095">
        <property type="entry name" value="ABC multidrug transporter Mdr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000218">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="211"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="532"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="108"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="796"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="796"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="812"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA56993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="824" mass="88323" checksum="8DDB160E8A12277F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNF0</accession>
    <name>G4MNF0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Elongation factor 1-gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_06936</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709676.1">
        <property type="nucleotide sequence ID" value="XM_003709628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNF0"/>
    <dbReference type="SMR" id="G4MNF0"/>
    <dbReference type="FunCoup" id="G4MNF0">
        <property type="interactions" value="1222"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MNF0"/>
    <dbReference type="GeneID" id="2685109"/>
    <dbReference type="KEGG" id="mgr:MGG_06936"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06936"/>
    <dbReference type="eggNOG" id="KOG0867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1627">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_3_0_1"/>
    <dbReference type="InParanoid" id="G4MNF0"/>
    <dbReference type="OMA" id="TQYFSWT"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03181">
        <property type="entry name" value="GST_C_EF1Bgamma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03044">
        <property type="entry name" value="GST_N_EF1Bgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000006">
        <property type="entry name" value="Elongation factor 1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000142">
        <property type="entry name" value="Elongation factor 1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1010:FF:000001">
        <property type="entry name" value="Elongation factor 1-gamma 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1010">
        <property type="entry name" value="Translation elongation factor EF1B, gamma chain, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050802">
        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001662">
        <property type="entry name" value="EF1B_G_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036433">
        <property type="entry name" value="EF1B_G_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF1">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00647">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01183">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89942">
        <property type="entry name" value="eEF1-gamma domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50040">
        <property type="entry name" value="EF1G_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="8">
        <location>
            <begin position="87"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="EF-1-gamma C-terminal" evidence="6">
        <location>
            <begin position="251"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="213"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA57064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="412" mass="47215" checksum="70D6DCA0475F71D7" modified="2011-12-14" version="1">MSFGKLYTYEKNPRSTAILAVAKANDTPLEVVNVDQEKNIPADYTSINKLGKVPTFVGADGYVLYECIAIAVYVTSQNEKTTLLGKTKQDYASILKWMSFFNQEILPHMGAWYRPLLGKDQYNKKSVEDASKRALKAISVVEEYLRDNTFLVGERITLADLFSVGIIARGFEFFFDTKWRQEYPNVTRWYTTVYDQPIYSAVAPKLELLETPALTNTPPKKAEQPKKEAKPAAAPAAAAEEDDEPKPQPKPKHPCDLLPKAAVPIDEWKRQYSNNPVPQAMEWFWKNMDLTKDYSIWKVEYKYNNELGVPFMSCNLIGGFEQRLEGSRKQLMGSASVYGDGHGSFIQGAFVIRGQEHEPVFNVAPDWESYTFTKLDPNNEEDRKYVRDEWEWERTVVKDGKEYPHYDGKVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNQ3</accession>
    <name>G4MNQ3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_14603</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708881.1">
        <property type="nucleotide sequence ID" value="XM_003708833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNQ3"/>
    <dbReference type="GeneID" id="5051594"/>
    <dbReference type="KEGG" id="mgr:MGG_14603"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14603"/>
    <dbReference type="HOGENOM" id="CLU_1525459_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNQ3"/>
    <dbReference type="OrthoDB" id="5232936at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465309" evidence="3">
        <location>
            <begin position="38"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA56269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="176" mass="19069" checksum="A950B5E502DA4750" modified="2011-12-14" version="1">MLRDRHTNNMYPAFRASHHTAALAFLVISLLCATILAAPVDITSSTKLQLPSSTTPSVTVQTDAIPDGSIKQPDTIADTTHEHQQHLLPRGVLQKRIDITPESGGAILTTLLVVVGCAIGLGAASIAVFGFEWKRWSRGVKRQDHIDVVTRIEKGKSVPSADEKGKANEDKNRNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MP56</accession>
    <name>G4MP56_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708927.1">
        <property type="nucleotide sequence ID" value="XM_003708879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MP56"/>
    <dbReference type="GeneID" id="2681066"/>
    <dbReference type="KEGG" id="mgr:MGG_02155"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02155"/>
    <dbReference type="eggNOG" id="ENOG502SHR0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_084275_1_0_1"/>
    <dbReference type="InParanoid" id="G4MP56"/>
    <dbReference type="OMA" id="TWYADSH"/>
    <dbReference type="OrthoDB" id="4831122at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465162" evidence="2">
        <location>
            <begin position="22"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="276" mass="29145" checksum="A64B91CBC0FF6463" modified="2011-12-14" version="1">MFFTRLATLTVASLMVSPITAGPINPRASSGNGQAIGESEVAVNTPEGVQMMSHSAYVSMLQEKGIQIGAPPPIHDDMVTYNAQQLAELEASEAAKKTDDAPPPPPGTLDSRGKCDKTTSVVIDNTTTFVDWDAQMSPVVCAQGNMMVAVASGYMVSNSIGVNAGLMPTMVKDVLSGSLNIDYTRSWTTSSVITTTGTVTDKNCGVMVTRPIVTRRTGRVFKGCLGALEQIGAFYADDHKEVTIAGMKWVEGAISMCMKPGINPPLSRCSGEGNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>G4MPC1</accession>
    <name>G4MPC1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_09175</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-A beta-lactamase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709786.1">
        <property type="nucleotide sequence ID" value="XM_003709738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MPC1"/>
    <dbReference type="SMR" id="G4MPC1"/>
    <dbReference type="STRING" id="242507.G4MPC1"/>
    <dbReference type="GeneID" id="2680271"/>
    <dbReference type="KEGG" id="mgr:MGG_09175"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09175"/>
    <dbReference type="eggNOG" id="ENOG502S4UR">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020027_11_1_1"/>
    <dbReference type="InParanoid" id="G4MPC1"/>
    <dbReference type="OMA" id="GMFNSSW"/>
    <dbReference type="OrthoDB" id="428260at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283:SF17">
        <property type="entry name" value="(LOVD), PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="4">
        <location>
            <begin position="11"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="233"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA57174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="433" mass="46848" checksum="D465A134933CAE61" modified="2011-12-14" version="1">MHPPTTKMADFDEMIEKAVQEGVAPGLVLIAGDKTGKLDYRKTFGNASLNGAGDTQQREPQPQPMSARDSAFTWMSLTKLPTAVAILQLVEQGRLSLDADVADQLPELAAQPVISSSSDGADTLVPRRAAITLRHLLSHTSGLQYPFIPGALAAYYERRARAGGEGFDMAKRRARVQERFGVPLVYEPGEGWCYGPGLDWAGLLLERTVDESLDAYVKRSVWAPLGVQEGEMPSYFPKTSSSSSSSSSDMNNVATSARGPNGKMVGVPDMPAPPAPEAAFGGEGMRGTMDTFVRLLRSLTLDDGVLLRPETAALLFEPQLRGRWDASKTALRDLLAGADWLSGVAPPQGDEYDWGLGGLLVDGDSHAYRRPGCLMWSGMFNSSWFIDRKAGVYGVFGTQCLPPGDSPIRNLTEAFQEEVYRRANKLNKSSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQ81</accession>
    <name>G4MQ81_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_09256</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709886.1">
        <property type="nucleotide sequence ID" value="XM_003709838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQ81"/>
    <dbReference type="STRING" id="242507.G4MQ81"/>
    <dbReference type="GeneID" id="2680192"/>
    <dbReference type="KEGG" id="mgr:MGG_09256"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09256"/>
    <dbReference type="eggNOG" id="KOG4400">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_396408_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQ81"/>
    <dbReference type="OMA" id="PTWRRCQ"/>
    <dbReference type="OrthoDB" id="7608935at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051644">
        <property type="entry name" value="TRAMP_AT-DNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="9">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="9">
        <location>
            <begin position="437"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="304"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="579"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="589"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="623"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="635"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="648"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="666"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA57274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="695" mass="74427" checksum="DB82C22405D2D4D7" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQD5</accession>
    <name>G4MQD5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_10637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710733.1">
        <property type="nucleotide sequence ID" value="XM_003710685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQD5"/>
    <dbReference type="GeneID" id="2682232"/>
    <dbReference type="KEGG" id="mgr:MGG_10637"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10637"/>
    <dbReference type="eggNOG" id="ENOG502RJMQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_842176_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQD5"/>
    <dbReference type="OMA" id="MELPAEF"/>
    <dbReference type="OrthoDB" id="5216550at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022190">
        <property type="entry name" value="DUF3716"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12511">
        <property type="entry name" value="DUF3716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="330" mass="36165" checksum="A19E8694C8FE19D9" modified="2011-12-14" version="1">MSFVAAESPPIHIKSSPGSTSGTEGSNSDSDSDGSDIGDIPYFLPDTDITAPSNNLSVDNFDQDILAQFLGDDGDSQDPVNDTVDEPDYLIRSDIEDPNEINIDVVRDILSQMPSNLAKNGATTAMLGMQPLRSCVIHPVWKSRKIIWKRLDNVEAVLMQIVGTENPIACKRCTDNRGPFVGWYSVPGVHNGGCGCCKYNAQTAKCSLYKGSKRPRRTSQRPLKRRKRGNEASNTRDAGPSVPAAQPLAIQNRNPVSLSPAYLVQPAPQQRVLQVPIPAELGWEDAMTLRRALQEMAEQLVFSPQGNKVVRRVLREFSGALEDFASEEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MR01</accession>
    <name>G4MR01_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709148.1">
        <property type="nucleotide sequence ID" value="XM_003709100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MR01"/>
    <dbReference type="GeneID" id="12984372"/>
    <dbReference type="KEGG" id="mgr:MGG_16109"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16109"/>
    <dbReference type="HOGENOM" id="CLU_2469521_0_0_1"/>
    <dbReference type="InParanoid" id="G4MR01"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="88" mass="9477" checksum="5C9E626756C32D2E" modified="2011-12-14" version="1">MPSTGLPAAREPRPPGREGGVSAESQKINIQGNHPSLPQSLPSTLPAFGQGIIARPSLPLVRFETRRVTDFPALCRAHPNPESGWEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRK1</accession>
    <name>G4MRK1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">dUTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_09934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710036.1">
        <property type="nucleotide sequence ID" value="XM_003709988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRK1"/>
    <dbReference type="STRING" id="242507.G4MRK1"/>
    <dbReference type="GeneID" id="2680904"/>
    <dbReference type="KEGG" id="mgr:MGG_09934"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09934"/>
    <dbReference type="eggNOG" id="ENOG502RZDE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030655_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRK1"/>
    <dbReference type="OMA" id="YGGPEGW"/>
    <dbReference type="OrthoDB" id="3257981at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="576" mass="63618" checksum="11B8C9C06477A970" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRR5</accession>
    <name>G4MRR5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16512</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710892.1">
        <property type="nucleotide sequence ID" value="XM_003710844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRR5"/>
    <dbReference type="GeneID" id="12986857"/>
    <dbReference type="KEGG" id="mgr:MGG_16512"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16512"/>
    <dbReference type="HOGENOM" id="CLU_2027177_0_0_1"/>
    <dbReference type="InParanoid" id="G4MRR5"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA58280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="122" mass="13254" checksum="D329E3CEC6540F49" modified="2011-12-14" version="1">MLHLAKASKWLVVRLRSENKHADDNVPLGVGTLRGPGRLRLHMARAPICPAQPSFVPAEMGTDRNLNPLSQQALCGANPKTTDTRPRATALAVYSPPRLVLGRTEKGLTRVARAQRSWTGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS96</accession>
    <name>G4MS96_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Epidermal growth factor receptor-like transmembrane-juxtamembrane segment domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_04490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710966.1">
        <property type="nucleotide sequence ID" value="XM_003710918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS96"/>
    <dbReference type="STRING" id="242507.G4MS96"/>
    <dbReference type="GeneID" id="2678076"/>
    <dbReference type="KEGG" id="mgr:MGG_04490"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04490"/>
    <dbReference type="eggNOG" id="ENOG502QRH7">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_642624_0_0_1"/>
    <dbReference type="InParanoid" id="G4MS96"/>
    <dbReference type="OMA" id="WIGCCET"/>
    <dbReference type="OrthoDB" id="4814718at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049328">
        <property type="entry name" value="TM_ErbB1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21314">
        <property type="entry name" value="TM_ErbB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Epidermal growth factor receptor-like transmembrane-juxtamembrane segment" evidence="6">
        <location>
            <begin position="283"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="215"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="309"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA58354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="427" mass="44801" checksum="DC9DA19445B3BBBC" modified="2011-12-14" version="1">MPRGTKYNPRAAMLLPEGLLPMLALFLSTSPIMVAAATIAAAGRVLPVPEGQYPLHMTIPASAWQPRETAGWTADAAVEKGADVPMSGFSPRPTDGPRFGSMDIFRRQAATLNPNECGFLPNGVAFSCPGDGASCKHDGTHLGCCQKDGSCKFRAKTCIDYKASVGGACNGITDPATRCCSESSNAFCFTLQFSTSTEPGKIITLLDCQASPGTGILYNSPPPRTTKASPTSKKSPTSTQPANSTTGYGSGPTNPSDGDRPGDPEQQQQPAPTSSPNTSKGVIAGGVVGGVAFLGLIGATVLFLIRRRKAPKTRASNSGGDTSMPGATYPPTSPYQTHLSASYGSPADTNTPFSVEQQQQQQQTQKQGWYPHSTHSSVHGTPQSTTPMQQAHSPYRPHVAPAELYHPHVIHELPGDSPPPRQGTNTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSE3</accession>
    <name>G4MSE3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EXS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_11390</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713562.1">
        <property type="nucleotide sequence ID" value="XM_003713514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSE3"/>
    <dbReference type="FunCoup" id="G4MSE3">
        <property type="interactions" value="55"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MSE3"/>
    <dbReference type="GeneID" id="2678085"/>
    <dbReference type="KEGG" id="mgr:MGG_11390"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11390"/>
    <dbReference type="eggNOG" id="KOG1162">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024081_2_1_1"/>
    <dbReference type="InParanoid" id="G4MSE3"/>
    <dbReference type="OMA" id="FRRWIWI"/>
    <dbReference type="OrthoDB" id="2159384at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        </source>
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        <source>
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    </evidence>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
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    <name>G4MSF8_PYRO7</name>
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    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Fungi</taxon>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        </location>
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        </location>
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        </location>
    </feature>
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        </location>
    </feature>
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            <end position="709"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA53770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="735" mass="80577" checksum="59C9B5FED71A1597" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTK9</accession>
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        <recommendedName>
            <fullName evidence="3">HPt domain-containing protein</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism evidence="4 5">
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyricularia</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003715327.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_07173"/>
    <dbReference type="eggNOG" id="KOG4747">
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        <property type="entry name" value="HPT domain"/>
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        <property type="entry name" value="HPT_dom_sf"/>
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    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
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        <property type="entry name" value="PHOSPHORELAY INTERMEDIATE PROTEIN YPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28242:SF52">
        <property type="entry name" value="PHOSPHORELAY INTERMEDIATE PROTEIN YPD1"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="43"/>
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        <location>
            <begin position="1"/>
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        <location>
            <position position="82"/>
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        <source>
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        <source>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA55568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="153" mass="17427" checksum="D358471DC9F35D86" modified="2011-12-14" version="1">MYSVKDSEKSDSEENADKMPDFGAHVDSTTFEQILEMDEDEAERDFSKPLVMGFFEQAEETFEKMDKALKDRDLKELSSLGHFLKGSSATLGFTKVKDSCQVIQQYGNKLKLDGTEEPSEDVCYEKIDKALVDAKKDMESLKKLLNEFFVIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTR1</accession>
    <name>G4MTR1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DOM34-interacting protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_04746</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat WDR3/UTP12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713707.1">
        <property type="nucleotide sequence ID" value="XM_003713659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTR1"/>
    <dbReference type="SMR" id="G4MTR1"/>
    <dbReference type="FunCoup" id="G4MTR1">
        <property type="interactions" value="1169"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTR1"/>
    <dbReference type="GeneID" id="2678069"/>
    <dbReference type="KEGG" id="mgr:MGG_04746"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04746"/>
    <dbReference type="eggNOG" id="KOG0306">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005318_0_1_1"/>
    <dbReference type="InParanoid" id="G4MTR1"/>
    <dbReference type="OMA" id="MNIPLTC"/>
    <dbReference type="OrthoDB" id="407922at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001884">
        <property type="entry name" value="WD domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000755">
        <property type="entry name" value="WD repeat-containing protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051570">
        <property type="entry name" value="TBC1_cilium_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN 3 WDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25172">
        <property type="entry name" value="Beta-prop_WDR3_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="851"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="427"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="508"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="607"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="649"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="696"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="7">
        <location>
            <begin position="833"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="751"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="758"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA53900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="968" mass="108138" checksum="BC8BEB64E174AE46" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTU7</accession>
    <name>G4MTU7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8004 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714548.1">
        <property type="nucleotide sequence ID" value="XM_003714500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTU7"/>
    <dbReference type="STRING" id="242507.G4MTU7"/>
    <dbReference type="GeneID" id="2679516"/>
    <dbReference type="KEGG" id="mgr:MGG_01570"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01570"/>
    <dbReference type="eggNOG" id="ENOG502QUVC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005053_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTU7"/>
    <dbReference type="OMA" id="WIAGLDQ"/>
    <dbReference type="OrthoDB" id="5300331at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058317">
        <property type="entry name" value="DUF8004"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39601:SF2">
        <property type="entry name" value="CHORIOGENIN HMINOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26013">
        <property type="entry name" value="DUF8004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8004" evidence="2">
        <location>
            <begin position="463"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="882"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="959"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="884"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="902"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="963"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1071"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1071" mass="117242" checksum="FD996A45A69209CF" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4MU86</accession>
    <name>G4MU86_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713774.1">
        <property type="nucleotide sequence ID" value="XM_003713726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MU86"/>
    <dbReference type="GeneID" id="12987231"/>
    <dbReference type="KEGG" id="mgr:MGG_15581"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15581"/>
    <dbReference type="HOGENOM" id="CLU_2831658_0_0_1"/>
    <dbReference type="InParanoid" id="G4MU86"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="66" mass="7034" checksum="C204FB88F655B811" modified="2011-12-14" version="1">MDAYPIEIQQHVGMYVLSTALSGAKGATIGSARGPWPKRHGGQGQAAQATKAHCNNQARMHDGEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUG3</accession>
    <name>G4MUG3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. LaeA methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715462.1">
        <property type="nucleotide sequence ID" value="XM_003715414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MUG3"/>
    <dbReference type="SMR" id="G4MUG3"/>
    <dbReference type="GeneID" id="2683130"/>
    <dbReference type="KEGG" id="mgr:MGG_07242"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07242"/>
    <dbReference type="eggNOG" id="ENOG502QWDP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010595_1_2_1"/>
    <dbReference type="InParanoid" id="G4MUG3"/>
    <dbReference type="OMA" id="HEGSYIY"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF14">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="335" mass="37808" checksum="FDA64989447D0535" modified="2011-12-14" version="1">MGDFPLTMNSVMPSNDIKYGEENHASLSDADATADSFREVQKENGRTYHSFRAGSYPFPNDDAENERLKFQYEIITEVLGRNYFAPFTKDTPPTRVLDIGTGPGQWAIEISDEFPEAEVIGTDLSPIQPNEVPENCYFYVDDSSEEWDFGFDFSYIHTRLTFGCFSDMRTQVIDQALRNLKPGGWLECQELDPVVACDDGTMPADYSPKQLTLALEAASRIAKRQFTCAPLIRGWLEEAGFVDVQQKVFKLPVNGWDASSPRASELGKMWFDNLSSGLGAVCTALLHRHANKQVEEIEVSLVDVRRQLRSQNIHAYHSLYVVWGRKPFEGEMTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4MV52</accession>
    <name>G4MV52_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_14755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713874.1">
        <property type="nucleotide sequence ID" value="XM_003713826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MV52"/>
    <dbReference type="SMR" id="G4MV52"/>
    <dbReference type="FunCoup" id="G4MV52">
        <property type="interactions" value="836"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MV52"/>
    <dbReference type="GeneID" id="5049746"/>
    <dbReference type="KEGG" id="mgr:MGG_14755"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14755"/>
    <dbReference type="eggNOG" id="KOG1299">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013933_3_1_1"/>
    <dbReference type="InParanoid" id="G4MV52"/>
    <dbReference type="OMA" id="VHQLNNA"/>
    <dbReference type="OrthoDB" id="10266265at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.830.10:FF:000002">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA54067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="592" mass="66531" checksum="99E1CCD57C098FD1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWF1</accession>
    <name>G4MWF1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_08345</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat MET30/SCONB/SCON-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715718.1">
        <property type="nucleotide sequence ID" value="XM_003715670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWF1"/>
    <dbReference type="SMR" id="G4MWF1"/>
    <dbReference type="STRING" id="242507.G4MWF1"/>
    <dbReference type="GeneID" id="2678612"/>
    <dbReference type="KEGG" id="mgr:MGG_08345"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08345"/>
    <dbReference type="eggNOG" id="KOG0274">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_103_3_1"/>
    <dbReference type="InParanoid" id="G4MWF1"/>
    <dbReference type="OMA" id="TMCRAAQ"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd22147">
        <property type="entry name" value="F-box_SpPof1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="443"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="690"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="806"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="846"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="888"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="135"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="329"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="537"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA55911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1033" mass="115160" checksum="43D62E6A3A4E896E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MWF5</accession>
    <name>G4MWF5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphorylcholine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715722.1">
        <property type="nucleotide sequence ID" value="XM_003715674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MWF5"/>
    <dbReference type="SMR" id="G4MWF5"/>
    <dbReference type="STRING" id="242507.G4MWF5"/>
    <dbReference type="GeneID" id="2678638"/>
    <dbReference type="KEGG" id="mgr:MGG_08342"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08342"/>
    <dbReference type="eggNOG" id="ENOG502SEU8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062627_0_0_1"/>
    <dbReference type="InParanoid" id="G4MWF5"/>
    <dbReference type="OMA" id="MQFHGVD"/>
    <dbReference type="OrthoDB" id="5182398at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466231" evidence="1">
        <location>
            <begin position="24"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="361" mass="39875" checksum="6AA7DC4C3D0FAD59" modified="2011-12-14" version="1">MKVNFSLALAGLAALASSSPCQAKPVTTNSTMLSHWPSAAATSLEAMIKRNAHTGAYAAFDMDNTSWRFDVEESLIPYLDNKGVLSRDKLDPSLKIIPFKDTATYKESLYSYYSRLCDIDAMVCYPWAAQVFSGMKLRELKGWVDELMTFEGGIINTTQWVGNAVQNVSVSRPIPFRAQQQLYNALMDNGISVYVVTASNEELVRMVASDPKYGYNVPPANVIGVTTLLSNASDPSNPTTARKAIEDGVYDPEAFLDLTITPYLWTPATWMSGKYGAILTYISQWRKAVLVAGDTPDSDGYMLFHDVDVAKGGVRLWINKKQSNMDQLQGMIANNTMEQASLGQEVTADKNWVIVKPEEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXP3</accession>
    <name>G4MXP3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714987.1">
        <property type="nucleotide sequence ID" value="XM_003714939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXP3"/>
    <dbReference type="GeneID" id="12985506"/>
    <dbReference type="KEGG" id="mgr:MGG_15808"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15808"/>
    <dbReference type="HOGENOM" id="CLU_970015_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXP3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="287" mass="31426" checksum="2C87353A7815F07A" modified="2011-12-14" version="1">MIPSKLSHTRKLVVPEPDRVFTFETAVWHLGIYRKASYSLISQTPPREDPSEAGAWATIQRPAVLGKSMVSIFDAVIDITHWQTWLTVGEVETTGKAGPVGQVHPVTPGVLLMNFGIVQSKEYLSIFSSTVSVLMSCVCRPSLGFPSLQCGDFLAGGHEIQDCLSGCLPLEGVLAAKLLKYAGNVSLGLNLPIRSLLTAMMQCFHSQYFDSMVSDCPCIIGVSKRLYHFPPGRSQVSVIQLADPRWSFSGRRSTFFPRASTARPTATGKRDLYTFDPSHRGDTTSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYH6</accession>
    <name>G4MYH6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine protease</fullName>
            <ecNumber evidence="6">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_10498</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S1B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="6"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713403.1">
        <property type="nucleotide sequence ID" value="XM_003713355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYH6"/>
    <dbReference type="SMR" id="G4MYH6"/>
    <dbReference type="GeneID" id="2682065"/>
    <dbReference type="KEGG" id="mgr:MGG_10498"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10498"/>
    <dbReference type="eggNOG" id="ENOG502SCHB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068119_1_0_1"/>
    <dbReference type="InParanoid" id="G4MYH6"/>
    <dbReference type="OMA" id="IMSSYEW"/>
    <dbReference type="OrthoDB" id="10037376at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050966">
        <property type="entry name" value="Glutamyl_endopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008256">
        <property type="entry name" value="Peptidase_S1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15462:SF8">
        <property type="entry name" value="SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00839">
        <property type="entry name" value="V8PROTEASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006991560" description="Serine protease" evidence="6">
        <location>
            <begin position="20"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="142"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA53596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="347" mass="37904" checksum="5158858A038A32C7" modified="2011-12-14" version="1">MYLPPVLLRLLGTASLCSAAAVKAFAPRHLPNFSPIPPGNLTEEQSVEIAAVALSSDGLQWAEEITMSDTAFRWFVHDPSVRLEGKEPTKGPAVEEKNQKDSSLKGRQNGVVKYISGMDDRVEEKRLAYPFSAMGQINILNHDGRRSRCSGALVGPRLVATARHCLNDDGKGAYTFHPAFHTVDRLPNATVTHVISIAHPNRKSLTNCDYVDDWAIMVLDEDLSEISGYIGAREFDDDVLNHESLHNYGYPGDLQSGVPYSQWGFAAQLDHENDLACSKNRQTPMSHQADTASGQSGGPIFTAGEHEDGVYLMGINVAVDPNRGRRALASHGAALMGSIVYARRYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYM2</accession>
    <name>G4MYM2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_01330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714254.1">
        <property type="nucleotide sequence ID" value="XM_003714206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYM2"/>
    <dbReference type="SMR" id="G4MYM2"/>
    <dbReference type="STRING" id="242507.G4MYM2"/>
    <dbReference type="GeneID" id="2679370"/>
    <dbReference type="KEGG" id="mgr:MGG_01330"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01330"/>
    <dbReference type="eggNOG" id="ENOG502QQCH">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020809_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYM2"/>
    <dbReference type="OMA" id="CQDARKF"/>
    <dbReference type="OrthoDB" id="10253390at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021829">
        <property type="entry name" value="DUF3419"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473">
        <property type="entry name" value="BTA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11899">
        <property type="entry name" value="DUF3419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA54447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="798" mass="89443" checksum="C341143DA09540E8" modified="2011-12-14" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="72" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYU6</accession>
    <name>G4MYU6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Elongation factor Tu</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_08162</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715132.1">
        <property type="nucleotide sequence ID" value="XM_003715084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYU6"/>
    <dbReference type="SMR" id="G4MYU6"/>
    <dbReference type="FunCoup" id="G4MYU6">
        <property type="interactions" value="863"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYU6"/>
    <dbReference type="GeneID" id="2678366"/>
    <dbReference type="KEGG" id="mgr:MGG_08162"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08162"/>
    <dbReference type="eggNOG" id="KOG0460">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYU6"/>
    <dbReference type="OMA" id="EGDKEWG"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000003">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF36">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="51"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA55325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="443" mass="48873" checksum="A791023011C3D28A" modified="2011-12-14" version="1">MSATFRSLAPFARTARFAFKKTGNPLVSLQQQSRSPVLNLRRGYAVYERTKPHVNIGTIGHVDHGKTTLSAAITKRQAEKGFANFLDYAAIDKAPEERKRGITISSAHIEYSTENRHYSHVDCPGHADYIKNMITGAANMDGAIIVVAASDGQMPQTREHLLLARQIGIQKIVVFVNKVDALDDPEMLELVEMEMRELLNSYGFAGDDTPVIMGSALCALNDKRPEIGQQKIDELLEAVDTWIPTPERDLDKPFLMSVEDVFTIGGRGTVVSGRVQRGILKRDAEIEIVGKSDEVVKTKVTDIETFKKSCEESRAGDNSGLLLRGVRREDIKRGQVIAAPGSIKAHKQFLVSLYVLTKEEGGRHTGFQENYMPQMYIRTASEACSLHWPEGTEDASSKMVMPGDNVEMTATLHSPIAVEPGLRINIREGGKTVATGLVTRILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ63</accession>
    <name>G4MZ63_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Methylenetetrahydrofolate reductase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_08171</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715143.1">
        <property type="nucleotide sequence ID" value="XM_003715095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ63"/>
    <dbReference type="SMR" id="G4MZ63"/>
    <dbReference type="FunCoup" id="G4MZ63">
        <property type="interactions" value="26"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZ63"/>
    <dbReference type="GeneID" id="2678407"/>
    <dbReference type="KEGG" id="mgr:MGG_08171"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08171"/>
    <dbReference type="eggNOG" id="KOG0564">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025841_2_1_1"/>
    <dbReference type="InParanoid" id="G4MZ63"/>
    <dbReference type="OMA" id="GLMPINS"/>
    <dbReference type="OrthoDB" id="16284at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="PHI-base" id="PHI:3824"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.220:FF:000002">
        <property type="entry name" value="Methylenetetrahydrofolate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004621">
        <property type="entry name" value="Fadh2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00677">
        <property type="entry name" value="fadh2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF1">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="10">
        <location>
            <begin position="417"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="10">
        <location>
            <begin position="608"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="343"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="578"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA55336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="690" mass="76278" checksum="BE214707B0911FE6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZI9</accession>
    <name>G4MZI9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase Gst3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714355.1">
        <property type="nucleotide sequence ID" value="XM_003714307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZI9"/>
    <dbReference type="SMR" id="G4MZI9"/>
    <dbReference type="FunCoup" id="G4MZI9">
        <property type="interactions" value="155"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZI9"/>
    <dbReference type="GeneID" id="2679237"/>
    <dbReference type="KEGG" id="mgr:MGG_01410"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01410"/>
    <dbReference type="eggNOG" id="KOG2903">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037263_0_1_1"/>
    <dbReference type="InParanoid" id="G4MZI9"/>
    <dbReference type="OMA" id="PWANRAI"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03190">
        <property type="entry name" value="GST_C_Omega_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000162">
        <property type="entry name" value="Glutathione S-transferase Gst3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047047">
        <property type="entry name" value="GST_Omega-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="GLUTATHIONYL-HYDROQUINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01206">
        <property type="entry name" value="Xi.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01148">
        <property type="entry name" value="Xi_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="240"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="405" mass="46075" checksum="783F9ABA9B03171B" modified="2011-12-14" version="1">MNRTFLHCLPRHKSTGIYSNFVTLSAATRTTKTTLNTPARRFLRLGPNPACVVQNKSHQIRMSSQSAAGKITDWVKPGDTSGEFKRQVSSFRNWVSSEAGAQFPAEKGRYHLYVSYACPWATRVLIARKLKGLEDVISFSSVHWHLGENGWRFPTAEEAAHPDGENVTPDPCPGHEAFTHLRQVYFAAEPEYEGRFTVPVLWDKVQKTIVSNESSEILRMFGSAFDGIVEDKFKGVNLYPESLRVQIEEAHGWQYDLINNGVYKSGFATTQEAYERNVTALFEALDRAEEHLAGAEGPYWFGKDITEVDIRLFVTLIRFDPVYVQHFKCNIRDIRSGYPHLHKWMRNLYWNVPAFKDTCNFLHIKNHYTKSHKQINPFSITPVGPLPDILPLDDEVPAVKAAKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZN8</accession>
    <name>G4MZN8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715209.1">
        <property type="nucleotide sequence ID" value="XM_003715161.1"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MZN8"/>
    <dbReference type="GeneID" id="2683041"/>
    <dbReference type="KEGG" id="mgr:MGG_07027"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07027"/>
    <dbReference type="eggNOG" id="ENOG502RA0T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003025_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZN8"/>
    <dbReference type="OMA" id="MPEIGYG"/>
    <dbReference type="OrthoDB" id="5382102at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42105">
        <property type="entry name" value="DIM2-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42105:SF1">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="790"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="963"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1097"/>
        </location>
    </feature>
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        <location>
            <begin position="1265"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1380"/>
            <end position="1409"/>
        </location>
    </feature>
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        <location>
            <begin position="1464"/>
            <end position="1765"/>
        </location>
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        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="173"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="245"/>
            <end position="257"/>
        </location>
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            <begin position="318"/>
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            <begin position="400"/>
            <end position="429"/>
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        <location>
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        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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        <location>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA55402.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1765" mass="191713" checksum="60C544D4039A5703" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4N051</accession>
    <name>G4N051_PYRO7</name>
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        <recommendedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_05329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM170 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712893.1">
        <property type="nucleotide sequence ID" value="XM_003712845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N051"/>
    <dbReference type="FunCoup" id="G4N051">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N051"/>
    <dbReference type="GeneID" id="2675743"/>
    <dbReference type="KEGG" id="mgr:MGG_05329"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05329"/>
    <dbReference type="eggNOG" id="ENOG502S0YM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071343_2_0_1"/>
    <dbReference type="InParanoid" id="G4N051"/>
    <dbReference type="OMA" id="GFEARCC"/>
    <dbReference type="OrthoDB" id="2131401at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019334">
        <property type="entry name" value="TMEM170A/B/YPR153W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22779">
        <property type="entry name" value="SD17342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22779:SF6">
        <property type="entry name" value="SD17342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10190">
        <property type="entry name" value="Tmemb_170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA53086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="13583" checksum="C3DA4DB9119988C1" modified="2011-12-14" version="1">MVFTKLFARADVFFGSNPPADYKAPPFPSLHWPLYEEGRFLYGARDMTIFTLLWTLSIYMIVHVGAAVLAITMHLGKRWSNWKYVWIVPIFYILVAGSEAVLAGGLVGAMCVLQPHTCSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0X7</accession>
    <name>G4N0X7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_09575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712162.1">
        <property type="nucleotide sequence ID" value="XM_003712114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0X7"/>
    <dbReference type="SMR" id="G4N0X7"/>
    <dbReference type="GeneID" id="5048945"/>
    <dbReference type="KEGG" id="mgr:MGG_09575"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09575"/>
    <dbReference type="eggNOG" id="ENOG502QPZ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039534_1_1_1"/>
    <dbReference type="InParanoid" id="G4N0X7"/>
    <dbReference type="OMA" id="NMANNDQ"/>
    <dbReference type="OrthoDB" id="507128at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054539">
        <property type="entry name" value="Beta-prop_PDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH_b-prop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22807">
        <property type="entry name" value="TrAA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="Soluble quinoprotein glucose dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465610" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroloquinoline quinone-dependent pyranose dehydrogenase beta-propeller" evidence="3">
        <location>
            <begin position="33"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA52355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="474" mass="50417" checksum="B0141168C9DF7066" modified="2011-12-14" version="1">MKSSAALVFTLLACLCAAQTDCKKVIVPNYQAPRVAPGWQAQVVASGLKKPRSIEFDREGGLLVVDAGAGVFRLVFEDHGGTCLEEKERVLLVNNTALNHGLALSADGNSLFASTVHSVFRWAYEAKGSSVSGNPQEIITGMRNQVLTTRTLTMAKKATGMLLVSRGSGGDDDSAALAAARDVNSGTSQIRAFDTLRTSDGSQAWEFNRAGRRMGWGLRNAVAVAEHPITGGIYSMDHSVDGIERNGTDISLRNPGEELNFHGFLNATEDDQGGNYGYPVCHAAGDPSRIPDGEDLEVGSQFGINTNASNSDATCNGNYTAPRLVFPAHYGPMDLKFNKEGSVAFLSFRGSMSKTNPVGYRVSTVEFDASRGQPRELSNSTTALKDLIFNGDGHNCPDNCMRPVGLAWDVKGRLWVTADSTGEIYVLEKQLETPTAGDGIMVTEQAKSAAAGSVATWGGLGLLFHAVVAVFAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>G4N144</accession>
    <name>G4N144_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713027.1">
        <property type="nucleotide sequence ID" value="XM_003712979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N144"/>
    <dbReference type="GeneID" id="2683737"/>
    <dbReference type="KEGG" id="mgr:MGG_07810"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07810"/>
    <dbReference type="HOGENOM" id="CLU_2184495_0_0_1"/>
    <dbReference type="InParanoid" id="G4N144"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466442" evidence="1">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="115" mass="11634" checksum="63EEF215412AF7D2" modified="2011-12-14" version="1">MQFSTLTLLAASAFIPAIYAASAAPQDTCHCTGDDKAASGVKSTTEQCCANAVFGGGVKAAGKFTGDVCDYTGVAAFKNFDIVTAIEGFDSCCRTTKPGGVQSAQGGQCQKSTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N193</accession>
    <name>G4N193_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_13398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711379.1">
        <property type="nucleotide sequence ID" value="XM_003711331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N193"/>
    <dbReference type="SMR" id="G4N193"/>
    <dbReference type="STRING" id="242507.G4N193"/>
    <dbReference type="GeneID" id="5050323"/>
    <dbReference type="KEGG" id="mgr:MGG_13398"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13398"/>
    <dbReference type="eggNOG" id="KOG2361">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029724_1_1_1"/>
    <dbReference type="InParanoid" id="G4N193"/>
    <dbReference type="OMA" id="PAKYWDI"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052735">
        <property type="term" value="F:tRNA (cytidine-3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000221">
        <property type="entry name" value="Methyltransferase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF11">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="6">
        <location>
            <begin position="173"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA51572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="376" mass="42096" checksum="785C2B8560BCD0BC" modified="2011-12-14" version="1">MASTGVAEEAPAAPAAPSSAELSSGSSATDNKLVESVAALDVAGTPKEGVDEAAALPPHRSHDPDFNQKRADPFQFGSRYLNEDDDPYEFNAWDHVETDDVYKEYAEQQYALQRQSPVSDFDKHRFNSDPAKWWNQFYKNNTANFFKDRKWLQQEFPVLTKAIQEDTGPFVLLEIGAGAGNTAFPILAQNKNPNLKIHACDFSKKAVEVMRSHESYGTDQMQADVWDVSGDELPPGLTEGSVDVALMVFIFSALSPAQWAKAVANVHRLLKPGGVVCFRDYGRGDLAQVRFRKGRYLEENFYIRGDGTRVYFFETDELSTIWKTGGPPPAADAADQPSKPDLFEIEALGADRRLLVNRARKLKMYRCWLQGRFRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1C2</accession>
    <name>G4N1C2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamma-glutamyltranspeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_09541</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712200.1">
        <property type="nucleotide sequence ID" value="XM_003712152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1C2"/>
    <dbReference type="SMR" id="G4N1C2"/>
    <dbReference type="STRING" id="242507.G4N1C2"/>
    <dbReference type="MEROPS" id="T03.025"/>
    <dbReference type="GeneID" id="2680496"/>
    <dbReference type="KEGG" id="mgr:MGG_09541"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09541"/>
    <dbReference type="eggNOG" id="KOG2410">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014813_3_1_1"/>
    <dbReference type="InParanoid" id="G4N1C2"/>
    <dbReference type="OMA" id="EGNMVSY"/>
    <dbReference type="OrthoDB" id="2015213at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052896">
        <property type="entry name" value="GGT-like_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43881">
        <property type="entry name" value="GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43881:SF1">
        <property type="entry name" value="GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA52393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="611" mass="64599" checksum="8F50A7166B218A58" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4N1G8</accession>
    <name>G4N1G8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713042.1">
        <property type="nucleotide sequence ID" value="XM_003712994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N1G8"/>
    <dbReference type="GeneID" id="12985952"/>
    <dbReference type="KEGG" id="mgr:MGG_16937"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16937"/>
    <dbReference type="HOGENOM" id="CLU_2038522_0_0_1"/>
    <dbReference type="InParanoid" id="G4N1G8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="121" mass="13115" checksum="21EB04A4C72A08F0" modified="2011-12-14" version="1">MSILWPLSVNLESTEQLHSALTINYQARSADPVTARRVARYSPCSPKTPERSSASYVLTTANGSPRRTTSLVLAPGLRGPVFDIGAGQQGVPELCSALILEEVVKDNNPCKLVGWDLYTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2U9</accession>
    <name>G4N2U9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713205.1">
        <property type="nucleotide sequence ID" value="XM_003713157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2U9"/>
    <dbReference type="SMR" id="G4N2U9"/>
    <dbReference type="GeneID" id="2683887"/>
    <dbReference type="KEGG" id="mgr:MGG_07960"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07960"/>
    <dbReference type="eggNOG" id="ENOG502SCR5">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_689134_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2U9"/>
    <dbReference type="OMA" id="YPGMMWL"/>
    <dbReference type="OrthoDB" id="5588185at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="Nitrous oxide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465915" evidence="1">
        <location>
            <begin position="20"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="400" mass="42819" checksum="12F12C451415BBE7" modified="2011-12-14" version="1">MLPNVFFLALLAPCGLASAFSLPPFLEKLFTRDHNTGPIVSRRFTEYQLPAAAETHEFARVPNTDMIVLSQMSNSRLVKIQIDGTTEEPIAHHSFPMGANDRAGLHGIWPSEAEPGLVWISLQSENRIQLIDPGSDTLDEAPTVIRTIDVPAPGNGPHSIVEIDGRVWAGLKNPSADTGEYFVFSINVDGTEPTLYPCLRSPVFIKEDPLTGLIYATQDTESSIMRINVTSGETEQLPIPPSVGNTPVGMTAIEGGLLAGVWFSLAGNSTGGTGAFGRVVPETGELQFFQLTRPAALGFNAGLLHIADASNEAAGPGLWLLSTSLLSSRSGDALIRVGINDAISAITGEEYIALPTQDAWAHRVVVVNSTVMVSELRTYTLAHLVYENEVPGNWAPAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2V6</accession>
    <name>G4N2V6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_07966</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713212.1">
        <property type="nucleotide sequence ID" value="XM_003713164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2V6"/>
    <dbReference type="SMR" id="G4N2V6"/>
    <dbReference type="STRING" id="242507.G4N2V6"/>
    <dbReference type="GeneID" id="2683893"/>
    <dbReference type="KEGG" id="mgr:MGG_07966"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07966"/>
    <dbReference type="eggNOG" id="KOG2493">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015355_3_0_1"/>
    <dbReference type="InParanoid" id="G4N2V6"/>
    <dbReference type="OMA" id="AGFWFFG"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF55">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
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                <person name="Oh Y.Y."/>
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                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
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                <person name="Fitzgerald M."/>
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                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
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                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
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                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the polysaccharide monooxygenase AA13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711616.1">
        <property type="nucleotide sequence ID" value="XM_003711568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3D1"/>
    <dbReference type="SMR" id="G4N3D1"/>
    <dbReference type="GeneID" id="2683596"/>
    <dbReference type="KEGG" id="mgr:MGG_07676"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07676"/>
    <dbReference type="eggNOG" id="ENOG502QQKA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053021_2_0_1"/>
    <dbReference type="InParanoid" id="G4N3D1"/>
    <dbReference type="OMA" id="SCIDFTM"/>
    <dbReference type="OrthoDB" id="120613at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052282">
        <property type="entry name" value="Starch-active_LPMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14430)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36575:SF2">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466062" description="Chitin-binding type-4 domain-containing protein" evidence="8">
        <location>
            <begin position="18"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="9">
        <location>
            <begin position="18"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA51809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="229" mass="23377" checksum="56E86EAC8D1BE6D9" modified="2011-12-14" version="1">MQYSLLSVLSFATVVYGHGVVTSPPVRQAASAFGQACGQQMLSTESSDRLGNIQGLRQQAKADFDPTKCRLELCKGIPFADAKPGDVQKFSPGQTVPIKVNIGAPHTGIANVSVVDTATNSIIGQPLIEFQNYASTKTGVAKNNTDFSVTMPNTLPSTCGTAGACVLQWWWDSDEAKQTYMSCVDFTFGGAAGGGGAGNASTANAAAANGAAPSGGRATGSKAASASCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3E4</accession>
    <name>G4N3E4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711629.1">
        <property type="nucleotide sequence ID" value="XM_003711581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3E4"/>
    <dbReference type="GeneID" id="2683605"/>
    <dbReference type="KEGG" id="mgr:MGG_07685"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07685"/>
    <dbReference type="HOGENOM" id="CLU_2038520_0_0_1"/>
    <dbReference type="InParanoid" id="G4N3E4"/>
    <dbReference type="OrthoDB" id="10466713at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="121" mass="12744" checksum="82C36F5B9FBFCE6E" modified="2011-12-14" version="1">MAKSVAQTSKQMKRRSPPRYQRWGIGVSSPMRGGLLGQLDSSRFVTREAKRHERLPKAAVVGASESGEQTAGEAEDPSAGQSKPLGPNMECAAGLGGLFRSGVVACCFHLSSVTGEKTAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3I9</accession>
    <name>G4N3I9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 14">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_04972</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 14"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712471.1">
        <property type="nucleotide sequence ID" value="XM_003712423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3I9"/>
    <dbReference type="FunCoup" id="G4N3I9">
        <property type="interactions" value="530"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N3I9"/>
    <dbReference type="GeneID" id="2675367"/>
    <dbReference type="KEGG" id="mgr:MGG_04972"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04972"/>
    <dbReference type="eggNOG" id="KOG3187">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034302_6_1_1"/>
    <dbReference type="InParanoid" id="G4N3I9"/>
    <dbReference type="OMA" id="WSYILWQ"/>
    <dbReference type="OrthoDB" id="46988at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF3">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA52664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="230" mass="25456" checksum="2394A05EA5361E47" modified="2011-12-14" version="1">MATKKQSPAAVSAAPKSAKKTSSPIADGYLFFYNAASAILWAAVLGRVLLTNYLQGPEFVPLVVMDFARWTQTLAGLEILHVAIGLVRTSLITTAMQVGSRYLLVWGVVWLFPSVATSPGYSSMLSAWATTEVIRYTYFALLLAGVDAPGLAWLRYSTFIVLYPVGILSECWMMWLAATSRAEVTHPLLPTVYYIILFVVYPPGSVHMYSHMWKQRSKVLSKAKNHEKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4P9</accession>
    <name>G4N4P9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_05141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asaB hydroxylase/desaturase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712671.1">
        <property type="nucleotide sequence ID" value="XM_003712623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4P9"/>
    <dbReference type="SMR" id="G4N4P9"/>
    <dbReference type="STRING" id="242507.G4N4P9"/>
    <dbReference type="GeneID" id="2675695"/>
    <dbReference type="KEGG" id="mgr:MGG_05141"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05141"/>
    <dbReference type="eggNOG" id="ENOG502SJT0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042688_2_0_1"/>
    <dbReference type="InParanoid" id="G4N4P9"/>
    <dbReference type="OMA" id="WHHLGLH"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044053">
        <property type="entry name" value="AsaB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041278">
        <property type="entry name" value="CmcJ_NvfI_EfuI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598">
        <property type="entry name" value="BLL6449 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34598:SF3">
        <property type="entry name" value="OXIDOREDUCTASE AN1597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="31912" checksum="8DC7F91B0C5C3F0C" modified="2011-12-14" version="1">MQVEKQNVVTTLNYWDDPGDGSEPTPIYIGKGRITNERPHRAHPFVIHDITGDEDKYTLDGHGFQYCHHESQDKDFTDEANIEFVYYRECEELLKSITGAKSVHVFNHKVRRGPTQWHHLGLQNLKNRGPVTKTHVDQSYHGAELRLRWEFPDEADELVKRRYQIINVWRPIETIRKDPIAVADSSTVPDQDLVEAIMVENDFEGKQWVVRHNPEHRWHYKRCMTPQDVLLIKCFDSDTTGVARRALHSAFEDPSTAHLDSRQSIEVRCLVCYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5K4</accession>
    <name>G4N5K4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">C-4 methylsterol oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_06133</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712004.1">
        <property type="nucleotide sequence ID" value="XM_003711956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5K4"/>
    <dbReference type="FunCoup" id="G4N5K4">
        <property type="interactions" value="279"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5K4"/>
    <dbReference type="GeneID" id="2684265"/>
    <dbReference type="KEGG" id="mgr:MGG_06133"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06133"/>
    <dbReference type="eggNOG" id="KOG0873">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047036_5_0_1"/>
    <dbReference type="InParanoid" id="G4N5K4"/>
    <dbReference type="OMA" id="IVHEFIY"/>
    <dbReference type="OrthoDB" id="1658724at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="5">
        <location>
            <begin position="149"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA52197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="309" mass="36084" checksum="53A6CA7A22C0EA31" modified="2011-12-14" version="1">MEAFKNATIAAGATALNSSHGYFDVFEEVSKYHVQLSVLERLWAAWYLWWQNDTLATGIMSFAMHEIVYFGRSLPWIIIDAIPYFRQWKIQNQKIPTAKEQWDCTMLVLLGHFTVELPQIWVFHPLATYFGLDHGVPFPPAWKIAMQIAIFFVIEDLWHYLFHRALHYGPLYKNIHKLHHTYSAPFGLAAEYASPIEVMLLGFGVVGTPIVWTSITGDLHLFTMYLWIVLRLFQAIDAHSGYDFPWSLRKFLPFWGGADFHDLHHERFIGNYASSFRWWDWVFDTEAGDEPARKRREKKLAALKAKKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5V4</accession>
    <name>G4N5V4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SRR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716049.1">
        <property type="nucleotide sequence ID" value="XM_003716001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5V4"/>
    <dbReference type="GeneID" id="2678838"/>
    <dbReference type="KEGG" id="mgr:MGG_08539"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08539"/>
    <dbReference type="HOGENOM" id="CLU_739818_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5V4"/>
    <dbReference type="OrthoDB" id="5230585at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012942">
        <property type="entry name" value="SRR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42080">
        <property type="entry name" value="SRR1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42080:SF3">
        <property type="entry name" value="SRR1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07985">
        <property type="entry name" value="SRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRR1-like" evidence="1">
        <location>
            <begin position="208"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="374" mass="43027" checksum="843FED09D827BBDA" modified="2011-12-14" version="1">MSDNITMSDVSADVFETRQEALDFVNGYYVDPKNPWFSPKERAEVYKRAGKLFKDGTGGHVTTTTITGHVILIPIVRLNDSPFWSHVAPEAYRDGKFALHWEELGEEDLRELLKVRSKFRPSLVYVTSDQVVKRIQDRPEGPIRKDDVVFSPIESVRWGYDPPVNYPGCVTAKKMSERLAQGLENWERTEQGRGFNRQVQAVKDDRGKNNGFEFKRVVGIALGTMTEPCSVYQHCMVISLARQLGIREVWLQDPAYSTADKKALHEHGAKIANDDRVFGHIYSDSIVVCIAPAIPALELMQARVAAFKEWPAMLVWDRVGWHEWYPDRCTTRVYDMMDKYEILDLESPLDRDEFLETTVYVRRREQEFSGMPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5V8</accession>
    <name>G4N5V8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716053.1">
        <property type="nucleotide sequence ID" value="XM_003716005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5V8"/>
    <dbReference type="GeneID" id="2678685"/>
    <dbReference type="KEGG" id="mgr:MGG_08543"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08543"/>
    <dbReference type="HOGENOM" id="CLU_152689_0_0_1"/>
    <dbReference type="InParanoid" id="G4N5V8"/>
    <dbReference type="OMA" id="CYSTENA"/>
    <dbReference type="OrthoDB" id="5186115at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465773" evidence="1">
        <location>
            <begin position="23"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="106" mass="11075" checksum="940105CF330EB614" modified="2011-12-14" version="1">MKTTATIILAIQALGSLTTAAANPTDLPLGVEVIEEAPGNLVVREVSASSNPLQKRCRECVHLAGKCTIGHGSCYAREKASCTWCGDKCGSICVMSGTKCSDWCGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>G4N657</accession>
    <name>G4N657_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_08576</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716100.1">
        <property type="nucleotide sequence ID" value="XM_003716052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N657"/>
    <dbReference type="GeneID" id="2678712"/>
    <dbReference type="KEGG" id="mgr:MGG_08576"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08576"/>
    <dbReference type="HOGENOM" id="CLU_2197478_0_0_1"/>
    <dbReference type="InParanoid" id="G4N657"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="108" mass="12246" checksum="AD5F91DCE45A1EB0" modified="2011-12-14" version="1">MFQLGLCIDKSKNHGGGTSDHEENKRLPSFPMIMLCIIFDIRREPRNRKPNSQRTKKAPFFGRTAYASNGLMALDGHDRNHALDELFPSVTLVAKPCRSQEATGPEFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4N666</accession>
    <name>G4N666_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Beta-glucosidase cel3A</fullName>
            <ecNumber evidence="5">3.2.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Beta-D-glucoside glucohydrolase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Cellobiase cel3A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Gentiobiase cel3A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">MGG_08583</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="5"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716109.1">
        <property type="nucleotide sequence ID" value="XM_003716061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N666"/>
    <dbReference type="SMR" id="G4N666"/>
    <dbReference type="STRING" id="242507.G4N666"/>
    <dbReference type="GeneID" id="2678705"/>
    <dbReference type="KEGG" id="mgr:MGG_08583"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08583"/>
    <dbReference type="eggNOG" id="ENOG502QR4D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_479856_0_0_1"/>
    <dbReference type="InParanoid" id="G4N666"/>
    <dbReference type="OMA" id="HRRCAQA"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF12">
        <property type="entry name" value="BETA-GLUCOSIDASE G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 3 N-terminal" evidence="20">
        <location>
            <begin position="190"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00070030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00078013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00083231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00083611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="EHA49790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="568" mass="61614" checksum="46E28B6AE5224EF1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6E1</accession>
    <name>G4N6E1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_14009</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716130.1">
        <property type="nucleotide sequence ID" value="XM_003716082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6E1"/>
    <dbReference type="SMR" id="G4N6E1"/>
    <dbReference type="STRING" id="242507.G4N6E1"/>
    <dbReference type="GeneID" id="2678801"/>
    <dbReference type="KEGG" id="mgr:MGG_14009"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14009"/>
    <dbReference type="eggNOG" id="KOG1911">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_787719_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6E1"/>
    <dbReference type="OMA" id="NAETMEH"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="221"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="71"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="270"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="341"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA49811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="352" mass="37540" checksum="02D41039C9856D80" modified="2011-12-14" version="1">MPPPLPDQEDNVFGNENDMFTSDDIVANGDAHDEPLGTMVHLGDEADNEVGYNAMEPELAGHINYLATQPVSDPALDNQESIVPTTGKKRGRPSLPRPLSRNGTPAKTPTKPGRPSKTPRTEKASKGAKTAVLTGSARKRNADAATNDAPPAKRARGGKPLKAERTPERIQSRRGAAEAAKATFSTALKRAKIVESSDPAPKKRGRKVKATAASVVSSEAYEVEKILDSSVDADTKQLMYLVKWKDYASSENTWEPKKNLSGASEVIKKFNATKKSEEPVAKKPRGRKPDAIARTAKTPGRKPGASKPGPSKTGRKPGRKPVTATAASKTTVMAEVAAPKKPGRKPRAAHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6S1</accession>
    <name>G4N6S1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">MGG_03677</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. GCN5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716207.1">
        <property type="nucleotide sequence ID" value="XM_003716159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6S1"/>
    <dbReference type="SMR" id="G4N6S1"/>
    <dbReference type="FunCoup" id="G4N6S1">
        <property type="interactions" value="418"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N6S1"/>
    <dbReference type="GeneID" id="2677008"/>
    <dbReference type="KEGG" id="mgr:MGG_03677"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03677"/>
    <dbReference type="eggNOG" id="KOG1472">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015741_1_1_1"/>
    <dbReference type="InParanoid" id="G4N6S1"/>
    <dbReference type="OMA" id="HQPPKEW"/>
    <dbReference type="OrthoDB" id="1937912at2759"/>
    <dbReference type="PHI-base" id="PHI:10771"/>
    <dbReference type="PHI-base" id="PHI:8610"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010484">
        <property type="term" value="F:histone H3 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05509">
        <property type="entry name" value="Bromo_gcn5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000004">
        <property type="entry name" value="Histone acetyltransferase KAT2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="63"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="14">
        <location>
            <begin position="305"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="EHA49888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="400" mass="46135" checksum="65CAE40C2075816F" modified="2011-12-14" version="1">MSTATEDSTNGKRKATEDPASPVSAKRPKHESPDSPEKKKPNEIARIPFPEKPAVIEERNGEIEFRVVNNDNERESLIILTGLKCIFQKQLPKMPKDYIARLVYDRTHLSIAIVKKPLEVVGGITYRPFKGRQFAEIVFCAISSDQQVKGYGAHLMSHLKDYVKATSDVMHFLTYADNYAIGYFKKQGFTKEITLPKSVWMGYIKDYEGGTIMQCSMLPRIRYLEMGRMLLKQKECVHAKIRAFSKSHIVHQPPKQWKNGIEPIDPLSISAIRASGWSPDMDELARQPRHGPNYNQLLHLLNDMQNHQSAWPFLVPVNKDDVADYYEVIKEPMDLSTMENKLEMDQYPTPEDFIRDAKLIFDNCRKYNNESTPYAKSANKLEKFMWQQIKAIPEWSHLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6X6</accession>
    <name>G4N6X6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_12819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717059.1">
        <property type="nucleotide sequence ID" value="XM_003717011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6X6"/>
    <dbReference type="SMR" id="G4N6X6"/>
    <dbReference type="STRING" id="242507.G4N6X6"/>
    <dbReference type="GeneID" id="2684657"/>
    <dbReference type="KEGG" id="mgr:MGG_12819"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12819"/>
    <dbReference type="eggNOG" id="ENOG502RKSU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_288863_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6X6"/>
    <dbReference type="OMA" id="ELETEWH"/>
    <dbReference type="OrthoDB" id="5228469at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="291"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="319"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="667"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="794"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA50740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1063" mass="119722" checksum="C4BCFC12F580323D" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
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    <name>G4N728_PYRO7</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003716212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N728"/>
    <dbReference type="GeneID" id="12984387"/>
    <dbReference type="KEGG" id="mgr:MGG_17055"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17055"/>
    <dbReference type="HOGENOM" id="CLU_2469534_0_0_1"/>
    <dbReference type="InParanoid" id="G4N728"/>
    <dbReference type="OrthoDB" id="10441726at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="88" mass="9783" checksum="F04ECA1E0CAF06AD" modified="2011-12-14" version="1">MAENGHDSPIKIFERATGILWTLEFGSARSQPGTVWWHLLLLGTICRSTPRATPYLAKLAFPCCAVLSCPLSNNQGTRLYRTPNSLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7D9</accession>
    <name>G4N7D9_PYRO7</name>
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        <recommendedName>
            <fullName evidence="5">Circumsporozoite protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03593</name>
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    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716317.1">
        <property type="nucleotide sequence ID" value="XM_003716269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7D9"/>
    <dbReference type="STRING" id="242507.G4N7D9"/>
    <dbReference type="GeneID" id="2676798"/>
    <dbReference type="KEGG" id="mgr:MGG_03593"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03593"/>
    <dbReference type="eggNOG" id="ENOG502QUVP">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038962_0_0_1"/>
    <dbReference type="InParanoid" id="G4N7D9"/>
    <dbReference type="OMA" id="KCTPTID"/>
    <dbReference type="OrthoDB" id="2141239at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465818" description="Circumsporozoite protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="33820" checksum="C79AB736104644CF" modified="2011-12-14" version="1">MSSTKAFIVAALVAYVEARFNQEQIPVSAIQALGSFGNPGQAATLAGSVPGVLLAAAKACDKVELADKIVNELGTDPSVIAAAKGLLAAEMNFNPFAVKTNKICDDASLPATAELRGVIPKVDPSTDPTGIQNANAEKSITTPFSANGLSIAAITQAQGFTNFTKGDTGVLASGGAGGASGGGAASGGASGGGAASGGAAAGGNGAKGNQNSCNGQQQQGNNNSTGNANNNNNNNGGGANNGGGAASGAADFGKCKPTIDLKGGRANRPATELTFLPTDPLVAQGQQEALNPNIITNRVCDQLTNVCNANAAAKALCQEAKAKVQAAGTKDQSTADLFNSLLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N7E3</accession>
    <name>G4N7E3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein s17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_03588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716321.1">
        <property type="nucleotide sequence ID" value="XM_003716273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N7E3"/>
    <dbReference type="STRING" id="242507.G4N7E3"/>
    <dbReference type="GeneID" id="2677004"/>
    <dbReference type="KEGG" id="mgr:MGG_03588"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03588"/>
    <dbReference type="eggNOG" id="ENOG502S1YD">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029378_0_1_1"/>
    <dbReference type="InParanoid" id="G4N7E3"/>
    <dbReference type="OMA" id="FTIQIQV"/>
    <dbReference type="OrthoDB" id="2336871at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053216">
        <property type="entry name" value="Appressorial_penetr-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587:SF2">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34587">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA50002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="44180" checksum="1F5B2586AB2539B6" modified="2011-12-14" version="1">MDVTVGFSIYFHRPPTQEACFTFTSSQGQPLTATAERITNFGSFIHSLSRVSYWGRMVSRKVLSAVALFSTLALAQNNNNNNNGQNNNNNNNGGDATQLAPNAVQSGSFFDGSDAIGANDAQAQSDVSQNNFINFCAGQTLTNGLQLVDGSCNGIPMGQIPSKQNMVASVIINPKMGDNIPEGQDFQIQVQTINLQAGSFTNAVATYYTAPQKLNGQGQIIGHTHVTVQDLGNSLNPTQPPDPTQFAFFKGIDDAGNGQGLLAATVEGGLPAGNYRVCTLTSGSNHQPVIMPVAQRGSQDDCQKFTVTANGQGNNNGQNNNGQNNNGQNNNGQNNNGQNNGGQNNGGQNNGGQNNGGQNNGGQNNGGQNNGGQNNGGQNNGGNFGGNFGKNNFRNRRQRNRRQDVSENVPRAFRNFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4N913</accession>
    <name>G4N913_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transaldolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717427.1">
        <property type="nucleotide sequence ID" value="XM_003717379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N913"/>
    <dbReference type="SMR" id="G4N913"/>
    <dbReference type="STRING" id="242507.G4N913"/>
    <dbReference type="GeneID" id="2681687"/>
    <dbReference type="KEGG" id="mgr:MGG_10076"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10076"/>
    <dbReference type="eggNOG" id="KOG2772">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047470_1_1_1"/>
    <dbReference type="InParanoid" id="G4N913"/>
    <dbReference type="OMA" id="PIKPHDQ"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF39">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA51108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="40254" checksum="F46FDAFE4E9A094E" modified="2011-12-14" version="1">MAAATQKSCLQKLEEMLDVDVDDMDADYIRSMPIKPHDQTSNQAFVDVALAQESNKDLVFQVATEMKGSDWLAVYTRIAVLMCKKNLDLISGRVLLQTSPSKAYDTAATLAHARLYDAEFTRAGVPRDRFCIKIPSTGPGLNAAKVLQGEGISTLGTALFSVVQAVACSQAGCLSISPYFNEIYAHDLSKRDQVWPKTTDPVTQHPMAPRLVHILETYRRLYKETGKMQPLVKNASFISVEEAMAAAEMGCQSATLSREILTKLAETPYDANTQPGEGRPKPPHAYNAPEPLPARLQPLLKHDPLTEGWDGSSPSTDVDYLADGGAALQAAIEADPATQKRVRDALEFFVDAEERSRKRIETVMAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N951</accession>
    <name>G4N951_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cellulose-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716614.1">
        <property type="nucleotide sequence ID" value="XM_003716566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N951"/>
    <dbReference type="SMR" id="G4N951"/>
    <dbReference type="STRING" id="242507.G4N951"/>
    <dbReference type="GeneID" id="2676889"/>
    <dbReference type="KEGG" id="mgr:MGG_03338"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03338"/>
    <dbReference type="eggNOG" id="ENOG502SPIJ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044083_4_0_1"/>
    <dbReference type="InParanoid" id="G4N951"/>
    <dbReference type="OMA" id="ITCWRAL"/>
    <dbReference type="OrthoDB" id="2119228at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01833">
        <property type="entry name" value="XynB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF2">
        <property type="entry name" value="CELLULOSE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465958" evidence="1">
        <location>
            <begin position="20"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="2">
        <location>
            <begin position="28"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA50295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="231" mass="24933" checksum="8B9B72AC549A48F2" modified="2011-12-14" version="1">MHFTYGLTAVACLVGTALGQAKVKFMPLGDSITEITCWRATVWDNLVSAGLSSRTDFVGSSTTNPQNCQPRNGNWNRRHEGHSGYQAVDIVRNNLPGWLNQNVPDVVNFMLGTNDVNLGNRQTSEILNAYTGIVQQLRAKNPRVKIMVDTVLPLPFKQAPITALNNAIPGWAAQLNTAQSPIVVVDVAAGYPTSALRDQVHPNAAGDAIIAGKITPVLTRLIRDVIAEKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA30</accession>
    <name>G4NA30_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BPL/LPL catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_09756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA51276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717595.1">
        <property type="nucleotide sequence ID" value="XM_003717547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA30"/>
    <dbReference type="SMR" id="G4NA30"/>
    <dbReference type="FunCoup" id="G4NA30">
        <property type="interactions" value="396"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NA30"/>
    <dbReference type="GeneID" id="2680755"/>
    <dbReference type="KEGG" id="mgr:MGG_09756"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09756"/>
    <dbReference type="eggNOG" id="KOG0325">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035168_0_2_1"/>
    <dbReference type="InParanoid" id="G4NA30"/>
    <dbReference type="OMA" id="TEEPMWY"/>
    <dbReference type="OrthoDB" id="19908at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF7">
        <property type="entry name" value="LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="53"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="343" mass="36798" checksum="ADDA7F6430D46422" modified="2011-12-14" version="1">MSHLGRVGRVALQHIHLPSNAFTHAYPPYALAAALQSRLQRALLDSKSDPSLSPPPPTIISFTPKPTYTLGRRQTVGSDINVDALSRPLIVTHPRSDPGNEERMRPIVLRSLRGGQMTYHGPGQVVIWPVLDLQPASGGYKSMGVRQYADLLQDVTSDLVRNSPHLQGKKLETVKTCDPGVWVAETAQQKPRKIAAMGVHLRRHVTGLGVALNLTTPGTEANVGVEKDSNGEDNNPWLRFVPCGLEGKAVTSVFLEAQGWNNAVSRDSTPASDLALLPDPGKGCAQTWAGLFANYLGLDYNPGAVDEDVTSNMEGLTAEARSIEAEIKVNSDGDSAPEAAAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4NA78</accession>
    <name>G4NA78_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside-diphosphate-sugar epimerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_08447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715947.1">
        <property type="nucleotide sequence ID" value="XM_003715899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NA78"/>
    <dbReference type="STRING" id="242507.G4NA78"/>
    <dbReference type="GeneID" id="2678759"/>
    <dbReference type="KEGG" id="mgr:MGG_08447"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08447"/>
    <dbReference type="eggNOG" id="ENOG502S03H">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071330_5_0_1"/>
    <dbReference type="InParanoid" id="G4NA78"/>
    <dbReference type="OMA" id="CGVEHPK"/>
    <dbReference type="OrthoDB" id="9975943at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097:SF8">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="28258" checksum="13F5C370ACDDC941" modified="2011-12-14" version="1">MHTILTGATGMVGSAALATMLANPAITRITILSRRAVPQAIAAADPRVSVILHDNFASYDADLRNRVKDAHGCVWAMGVSTTQVSDPVEYERITKTFPLAAAKTFGEMALEQGRPFNFVYVSASGVDAEEPAKSPRMWARVKGETERGLAILADENPLMHTRSFRTAFVDPAEHEQIKPYLPQRQPIMRVAEKVLIPALRVFWKSGWGPSEPLGNFLTNLAVDKYSQEELVAAGAKKIGDGDFIAIENPTFQKLAGVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAX3</accession>
    <name>G4NAX3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_00690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718319.1">
        <property type="nucleotide sequence ID" value="XM_003718271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAX3"/>
    <dbReference type="GeneID" id="2675139"/>
    <dbReference type="KEGG" id="mgr:MGG_00690"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00690"/>
    <dbReference type="HOGENOM" id="CLU_1928040_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAX3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="131" mass="14666" checksum="B84E97C2599AFEF7" modified="2011-12-14" version="1">MSLMVSYSRLHCVTRFYSRRPSPRGGSTYPTLLRPRVDRHACRWCVFGSVKGEKTTHPPPPETRYMGEQLPRQLEIYLSLLANTGIDDGYNQVLHDVKKPGPMTSLAPAVPVYGSTRLYQESQGALDTSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBC0</accession>
    <name>G4NBC0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA methyltransferase FtsJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718466.1">
        <property type="nucleotide sequence ID" value="XM_003718418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBC0"/>
    <dbReference type="SMR" id="G4NBC0"/>
    <dbReference type="STRING" id="242507.G4NBC0"/>
    <dbReference type="GeneID" id="2675092"/>
    <dbReference type="KEGG" id="mgr:MGG_00579"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00579"/>
    <dbReference type="eggNOG" id="ENOG502S5H8">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043071_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBC0"/>
    <dbReference type="OMA" id="THYEDER"/>
    <dbReference type="OrthoDB" id="417125at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="1">
        <location>
            <begin position="97"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="373" mass="42032" checksum="3115886394BC3604" modified="2011-12-14" version="1">MDSTIKPPDQASQLYAPPAKNGIATPATKLNQYLIENLQEARELFELRRECWGSEKADRYLKKKRKYADNANEKAQLGFFKLMRSLGHQMNRATFALKIKKRTKAPAVLDLCIAPGGFAAAALRINPQASVCGFSLPEESGGHKLHLLSQDKSLTSRVNVEFRDITMMAAEMGCDPDDIPAEHPEAAEFSFDRPFADQKFSLAICDGQVLRTHDRCAYRGRHEPARLTASQFVMALRRVRTNGTIVALTHQVDSLHTFCKLHSLASFSELKLFKPVEEFGKQPSFYIVATNVKPCSEGAKQAIEECMRAWKSATFDFDKENNKEIYGAVSLEQFDKMLDEFGPAYLELARPILAIEAAALRRAPWMRRQQQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NBS4</accession>
    <name>G4NBS4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ER membrane protein SH3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718566.1">
        <property type="nucleotide sequence ID" value="XM_003718518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NBS4"/>
    <dbReference type="FunCoup" id="G4NBS4">
        <property type="interactions" value="55"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NBS4"/>
    <dbReference type="GeneID" id="2675052"/>
    <dbReference type="KEGG" id="mgr:MGG_00496"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00496"/>
    <dbReference type="eggNOG" id="ENOG502RXJB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080510_0_0_1"/>
    <dbReference type="InParanoid" id="G4NBS4"/>
    <dbReference type="OMA" id="ANMLFDG"/>
    <dbReference type="OrthoDB" id="5229808at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013248">
        <property type="entry name" value="Psh3/Shr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228:SF1">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08229">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029187">
        <property type="entry name" value="Shr3_AAP_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00786">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="216" mass="23819" checksum="C7315E109EADDDDC" modified="2011-12-14" version="1">MDAKWIDWSKTTRSKDYRGSSSFATFMIIGPVCFFLGILFASFPYDFPLLWTSDPVPPSYYDQLATHLRFMHAAPPLISRVLNIVVFVGFCGFFAKLFRPSEANVLFDGSSLVLYVIGVGIYLANIVKGLRDVTADVWGADGKGTLNHEGPISGEVKLSREDSLKVLSASNTILALVLVGVLVLQAGEWYAERKEADDEEVREAGDKKTAASKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND03</accession>
    <name>G4ND03_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718777.1">
        <property type="nucleotide sequence ID" value="XM_003718729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND03"/>
    <dbReference type="GeneID" id="12985001"/>
    <dbReference type="KEGG" id="mgr:MGG_17480"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17480"/>
    <dbReference type="HOGENOM" id="CLU_1267122_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND03"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="218" mass="22966" checksum="30E61836FF624483" modified="2011-12-14" version="1">MTSNWACFRLPEVAADELPQLPSQGNPESGQATLDCPIGKMIIGALGKASFRLIFPSSAEAQMVAIVATLYTCAPLRTALATSCGPPTGAYGRGDMLAPAALPETGHQHLGGGGIVEMPSTEFSVAAGRAVWSPCWVALGCLPGEYLVSAEYRAWGAGSLDNGEPPFSYQTIHKYALRGAVVVLVLVAMIGSRWFRPKPKEGVLREAAASLWPSRGHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDG0</accession>
    <name>G4NDG0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718033.1">
        <property type="nucleotide sequence ID" value="XM_003717985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDG0"/>
    <dbReference type="GeneID" id="5050628"/>
    <dbReference type="KEGG" id="mgr:MGG_11104"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11104"/>
    <dbReference type="HOGENOM" id="CLU_2794443_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDG0"/>
    <dbReference type="OMA" id="FFSFELR"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="68" mass="7367" checksum="A4E5FC3B49BB97BA" modified="2011-12-14" version="1">MAQGEKPLERAALMAAKDRQKTSSASKGVTNPPVQNQATQTNPTSLLGPTSRPLHKIDGLTFFSFELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDP4</accession>
    <name>G4NDP4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718066.1">
        <property type="nucleotide sequence ID" value="XM_003718018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDP4"/>
    <dbReference type="GeneID" id="12984012"/>
    <dbReference type="KEGG" id="mgr:MGG_17349"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17349"/>
    <dbReference type="HOGENOM" id="CLU_1611102_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDP4"/>
    <dbReference type="OrthoDB" id="5772781at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA48482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="165" mass="18514" checksum="909700CB9CDFC720" modified="2011-12-14" version="1">MPSGTKIISAVSSGVSPWAKTVKINVVQLDGAPKRYCLKASILSTFADGRFRLECQALCEGEYESQLLIEEAVGRGFGPIAWAWGELVLRRRLSPFIEQSSLTGRFGFHCATVCGSMQRTVLWDDKWANSFTHLFKDVIGYDNRVNPPWPEYDRACRITIDLIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NE85</accession>
    <name>G4NE85_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17524</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA49414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718998.1">
        <property type="nucleotide sequence ID" value="XM_003718950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NE85"/>
    <dbReference type="GeneID" id="12985089"/>
    <dbReference type="KEGG" id="mgr:MGG_17524"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17524"/>
    <dbReference type="HOGENOM" id="CLU_3106883_0_0_1"/>
    <dbReference type="InParanoid" id="G4NE85"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="51" mass="5730" checksum="6F6AC7DCB99955B0" modified="2011-12-14" version="1">MARNRWFNPLAVEPVAEVSGQCTQQRRNGHLLTEKGSWAGRLSHPSLLRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEF7</accession>
    <name>G4NEF7_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719018.1">
        <property type="nucleotide sequence ID" value="XM_003718970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEF7"/>
    <dbReference type="SMR" id="G4NEF7"/>
    <dbReference type="GeneID" id="12985123"/>
    <dbReference type="KEGG" id="mgr:MGG_17530"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17530"/>
    <dbReference type="HOGENOM" id="CLU_1787217_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEF7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
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            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466178" evidence="1">
        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA49434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="145" mass="16338" checksum="E44DDA7F792D4AE6" modified="2011-12-14" version="1">MFAWWLRYRFPIFWGGWGVQAADQGRQTPHTAQAIERELWSMKSNSACTDPLRVSVYSRHFVLACFCLLCSSWIGPERGKTSQATGVYGVHTVQYPVELHVIQAAVDRQEYGVLARLSTSAVFDNEEGKCQKEGCATDAIEDFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFC0</accession>
    <name>G4NFC0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Meiotically up-regulated gene 190 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_12184</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
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    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003719533.1"/>
    </dbReference>
    <dbReference type="GeneID" id="2677568"/>
    <dbReference type="KEGG" id="mgr:MGG_12184"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12184"/>
    <dbReference type="eggNOG" id="KOG1012">
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    <dbReference type="OrthoDB" id="419768at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04041">
        <property type="entry name" value="C2A_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04052">
        <property type="entry name" value="C2B_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21676">
        <property type="entry name" value="SMP_Mug190"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057349">
        <property type="entry name" value="C2_Mug190_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037767">
        <property type="entry name" value="C2A_Mug190-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037765">
        <property type="entry name" value="C2B_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348:SF2">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47348">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25331">
        <property type="entry name" value="C2_Mug190_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
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        <property type="match status" value="2"/>
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    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
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    <keyword evidence="9" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
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            <end position="329"/>
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    </feature>
    <feature type="domain" description="SMP-LTD" evidence="14">
        <location>
            <begin position="364"/>
            <end position="639"/>
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    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
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    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="853"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="107"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="225"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1074"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1213"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1260"/>
            <end position="1272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EHA47214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1387" mass="155870" checksum="386086AA0307EFC3" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFF5</accession>
    <name>G4NFF5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Cutinase</fullName>
            <ecNumber evidence="3 12">3.1.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">MGG_14959</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>cutin + H2O = cutin monomers.</text>
            <dbReference type="EC" id="3.1.1.74"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cutinase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.74" evidence="3 12"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719550.1">
        <property type="nucleotide sequence ID" value="XM_003719502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFF5"/>
    <dbReference type="SMR" id="G4NFF5"/>
    <dbReference type="STRING" id="242507.G4NFF5"/>
    <dbReference type="ESTHER" id="mago7-g4nff5">
        <property type="family name" value="Cutinase"/>
    </dbReference>
    <dbReference type="GeneID" id="12986005"/>
    <dbReference type="KEGG" id="mgr:MGG_14959"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14959"/>
    <dbReference type="eggNOG" id="ENOG502S3AW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1008574_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFF5"/>
    <dbReference type="OrthoDB" id="2975078at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050525">
        <property type="term" value="F:cutinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000675">
        <property type="entry name" value="Cutinase/axe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043580">
        <property type="entry name" value="CUTINASE_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043579">
        <property type="entry name" value="CUTINASE_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011150">
        <property type="entry name" value="Cutinase_monf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250:SF1">
        <property type="entry name" value="CUTINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48250">
        <property type="entry name" value="CUTINASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01083">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00129">
        <property type="entry name" value="CUTINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01110">
        <property type="entry name" value="Cutinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00155">
        <property type="entry name" value="CUTINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00931">
        <property type="entry name" value="CUTINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 12" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="202"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="209"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="132"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR611150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="EHA47183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="276" mass="26167" checksum="8A86CA7ED6181D19" modified="2011-12-14" version="1">MTVVFARGTTEAGNAGTVVGPPFLQAIRKLAPGLSVNMQGVPYPANFAGIMAGGDRQGTAKMANIIKTLATDCPNTGIVISGYSQGAMLMHNAAAQLDPETASHVVAAVSFGDPFRRRPVNGVDQSRTLVVCHAGDNVCQGGGMILPAHLTYGQDVGKAAAFVMEAAAAVVASMGAAPATEAAPGTEAVPGAGAVLGAGAVPGTGGAPGTEAAPGTGASPGTEAAPGTGAAPGTEAAPGTGAAPGTEAAPGTGAAPGTEALPSTGASPGAQVGPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFJ5</accession>
    <name>G4NFJ5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GMP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719169.1">
        <property type="nucleotide sequence ID" value="XM_003719121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFJ5"/>
    <dbReference type="SMR" id="G4NFJ5"/>
    <dbReference type="FunCoup" id="G4NFJ5">
        <property type="interactions" value="110"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NFJ5"/>
    <dbReference type="GeneID" id="2678968"/>
    <dbReference type="KEGG" id="mgr:MGG_08802"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08802"/>
    <dbReference type="eggNOG" id="KOG3179">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054974_0_2_1"/>
    <dbReference type="InParanoid" id="G4NFJ5"/>
    <dbReference type="OMA" id="PWIQTLK"/>
    <dbReference type="OrthoDB" id="92161at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="1">
        <location>
            <begin position="102"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="253" mass="27835" checksum="656E5BCC02916353" modified="2011-12-14" version="1">MAAKPPTRLAILMADTPMPNTAAKYGDYGGLFTSLFTTAAQPEPIESILSITKHDIVNHVGSYPSLDDVDAVLITGSKHSAFADDAWIMALVDYTRRALLETNGRVKVVGICFGHQIVARALGGKVVVNEKGWEVAVTEVELTERAREFFGLETLRIHQMHRDIVPELPKTDPPTMLLASNNVCQVQGMLWPGRCVTVQGHPEFTEEVVREVLETRHDAGIHPDDLYNSGISRVANQHDGIAIAKGFLKFLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFN1</accession>
    <name>G4NFN1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoserine phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719205.1">
        <property type="nucleotide sequence ID" value="XM_003719157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFN1"/>
    <dbReference type="SMR" id="G4NFN1"/>
    <dbReference type="FunCoup" id="G4NFN1">
        <property type="interactions" value="30"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NFN1"/>
    <dbReference type="GeneID" id="2678923"/>
    <dbReference type="KEGG" id="mgr:MGG_08771"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08771"/>
    <dbReference type="eggNOG" id="ENOG502QRU0">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058495_1_0_1"/>
    <dbReference type="InParanoid" id="G4NFN1"/>
    <dbReference type="OMA" id="VPFHEFD"/>
    <dbReference type="OrthoDB" id="10014216at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050849">
        <property type="entry name" value="HAD-like_hydrolase_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006384">
        <property type="entry name" value="HAD_hydro_PyrdxlP_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01489">
        <property type="entry name" value="DKMTPPase-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181:SF2">
        <property type="entry name" value="PHOSPHORIC MONOESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181">
        <property type="entry name" value="UPF0655 PROTEIN YCR015C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="28831" checksum="DBD9D00A9A21BD56" modified="2011-12-14" version="1">MGSITATDELPALRSQPKIIFFTDFDGTITVQDSNDWLTDNLGYGREKRRTANIDVLEGRVDFRDVFTGMLESVPVPFNECVNLLLENVKLDPAFARFYEWCRDNNVPIVILSGGMRPIIQALLRKLIGEEAVNNIQIVSNDVAVRKGKTSMDEPNGWEIVFHDDSGFGHDKSIEIRKYSSLKEKPVMLYAGDGVSDLSAAKETDLLFAKEGRDLVKFCETEKVPYTTFSDFSSILETVKDLSDGKLSVKDVAKKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGF4</accession>
    <name>G4NGF4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_04329</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719478.1">
        <property type="nucleotide sequence ID" value="XM_003719430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGF4"/>
    <dbReference type="GeneID" id="2677381"/>
    <dbReference type="KEGG" id="mgr:MGG_04329"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04329"/>
    <dbReference type="eggNOG" id="KOG0255">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008455_8_4_1"/>
    <dbReference type="InParanoid" id="G4NGF4"/>
    <dbReference type="OMA" id="PMLSTCN"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF151">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
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    <reference evidence="2 3" key="1">
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            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
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                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
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                <person name="Kim S."/>
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                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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    <dbReference type="InParanoid" id="G4NHZ9"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="117" mass="12611" checksum="90CC770C994F7135" modified="2011-12-14" version="1">MLLQERVRQGSPVGSSRARAQTAGLQTARRFRDPAAARQGFCSCCRQQQSLRFRVLGKVQQAPTRGRPEVDGYGQAVVVGLVGPGFDGTGRGGHGSDCQEGGKLEQDCLELHVEDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIS6</accession>
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        <submittedName>
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    <gene>
        <name evidence="1" type="ORF">MGG_04131</name>
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    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
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                <person name="Kim S."/>
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                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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            <dbReference type="PubMed" id="15846337"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719699.1">
        <property type="nucleotide sequence ID" value="XM_003719651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIS6"/>
    <dbReference type="SMR" id="G4NIS6"/>
    <dbReference type="GeneID" id="2677549"/>
    <dbReference type="KEGG" id="mgr:MGG_04131"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04131"/>
    <dbReference type="eggNOG" id="ENOG502QSMW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026434_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIS6"/>
    <dbReference type="OMA" id="LWEFYLC"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF2">
        <property type="entry name" value="FATTY ACID C-METHYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="483" mass="53251" checksum="73072B9C041B4857" modified="2011-12-14" version="1">MAYIPAAITGPVARGTEVLRESLGSLTWGPAMALARPAVEAVFSQIEIGTLLLVDEPGGRRIVYGQKLPDRSNGTKLDEEPLPTRPSGVRKATTIPRVELVVKRDAFWMRLFLFADMGLAEAYMLGDVECADLTSFFQLFIVNRDQMGNGTTRFSAISGAITSLARTTNTLSNSLLNISAHYDISNEMFAAFLSPDMTYSCPVWKSVTDGSDEQEESLEAAQLTKLRRFITGARIKSTDHVLEIGTGWGSFAIEAVKATGCRVTSLTLSKEQKALAEARIADAGLSDRIEVLLKDYRALEAPEGRPFDKIVSIEMLEAVGQEFLSTYFACIDRLLKKDGGIAMFQCITMPEGRHEAYSKSEDFINHYIFPGGYLPSITQLLNHISKESQGTLIVEGVENIGGHYSKTLRLWKEAFLENFDSKIKPALKTEHAGMTDEAIAVFKNKWEYYFTYCEAGFLTKTLGDVIIAVGREGALELMEGIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4NK75</accession>
    <name>G4NK75_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cysteine-rich transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_17862</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endomembrane system</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CYSTM1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720541.1">
        <property type="nucleotide sequence ID" value="XM_003720493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NK75"/>
    <dbReference type="STRING" id="242507.G4NK75"/>
    <dbReference type="GeneID" id="12984718"/>
    <dbReference type="KEGG" id="mgr:MGG_17862"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17862"/>
    <dbReference type="eggNOG" id="ENOG502SBQW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_156676_0_1_1"/>
    <dbReference type="InParanoid" id="G4NK75"/>
    <dbReference type="OMA" id="CCLECLD"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051671">
        <property type="entry name" value="CYSTM1_HM_Tolerance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028144">
        <property type="entry name" value="CYSTM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35470">
        <property type="entry name" value="CADMIUM TOLERANT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35470:SF6">
        <property type="entry name" value="PROTEIN CYSTEINE-RICH TRANSMEMBRANE MODULE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12734">
        <property type="entry name" value="CYSTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cysteine-rich transmembrane" evidence="8">
        <location>
            <begin position="40"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA45798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="90" mass="9865" checksum="03ADE05C56036909" modified="2011-12-14" version="1">MSQYPPPQQMPYGSPPPPAGYPQGPPPPQGGYYPPPQPMGYYPPQQQAPPPQEEKKDRGCLYGCLATLCCCWLCGESCECCLECLFCCCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKM8</accession>
    <name>G4NKM8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SRR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721360.1">
        <property type="nucleotide sequence ID" value="XM_003721312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKM8"/>
    <dbReference type="GeneID" id="2682200"/>
    <dbReference type="KEGG" id="mgr:MGG_10587"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10587"/>
    <dbReference type="eggNOG" id="ENOG502SC31">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048152_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKM8"/>
    <dbReference type="OMA" id="TTSIYWK"/>
    <dbReference type="OrthoDB" id="5318346at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012942">
        <property type="entry name" value="SRR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42080">
        <property type="entry name" value="SRR1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42080:SF1">
        <property type="entry name" value="SRR1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07985">
        <property type="entry name" value="SRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRR1-like" evidence="2">
        <location>
            <begin position="97"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="318" mass="34632" checksum="6EBED12A198F095B" modified="2011-12-14" version="1">MAASPEGGAWHTVARRKKGPRSNNNPHTASRQAKAGLDQPDARSTSAINPIIKNGRLQEPPSTPEQHQSDLAEIDRTYARVRTAYISSASYAALEALVRAHAASHAPITRAICLGNGPLHAPDSSWDRRRAANIQTATFLALVELLAGDFVVGSSGDDKRPRIRCILQEPLYTAADREYLTTTLGCEVVDDPEALEHVTEDSLVWGVHMYHTVYGDILRRVAEPALLVGTPWDVWDALPPDEDGRVAESLKGLAEIDASAEYDLFTFPQDEGHFTFCDTGIYWRKAGTATAQKKSHIAETAVSEKDGAADLPEQKTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKT9</accession>
    <name>G4NKT9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">BTB/POZ domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03027</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720660.1">
        <property type="nucleotide sequence ID" value="XM_003720612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKT9"/>
    <dbReference type="SMR" id="G4NKT9"/>
    <dbReference type="FunCoup" id="G4NKT9">
        <property type="interactions" value="47"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NKT9"/>
    <dbReference type="GeneID" id="2682580"/>
    <dbReference type="KEGG" id="mgr:MGG_03027"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03027"/>
    <dbReference type="eggNOG" id="KOG0511">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022885_2_0_1"/>
    <dbReference type="InParanoid" id="G4NKT9"/>
    <dbReference type="OMA" id="EGARCIY"/>
    <dbReference type="OrthoDB" id="684045at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18497">
        <property type="entry name" value="BACK_ABTB1_BPOZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000248">
        <property type="entry name" value="Ankyrin repeat and BTB/POZ domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044515">
        <property type="entry name" value="ABTB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231:SF1">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="154"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="355"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="327"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="573"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA45917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="644" mass="72292" checksum="DE9A9B3F8852BDF0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLE5</accession>
    <name>G4NLE5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Histone-lysine N-methyltransferase ASH1L</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_02937</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720772.1">
        <property type="nucleotide sequence ID" value="XM_003720724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLE5"/>
    <dbReference type="SMR" id="G4NLE5"/>
    <dbReference type="STRING" id="242507.G4NLE5"/>
    <dbReference type="GeneID" id="2682490"/>
    <dbReference type="KEGG" id="mgr:MGG_02937"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02937"/>
    <dbReference type="eggNOG" id="KOG1083">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004379_1_0_1"/>
    <dbReference type="InParanoid" id="G4NLE5"/>
    <dbReference type="OMA" id="HNCRGVL"/>
    <dbReference type="OrthoDB" id="422362at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.270.10:FF:000037">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006560">
        <property type="entry name" value="AWS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17907">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00570">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AWS" evidence="11">
        <location>
            <begin position="463"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="9">
        <location>
            <begin position="521"/>
            <end position="637"/>
        </location>
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    <feature type="domain" description="Post-SET" evidence="10">
        <location>
            <begin position="645"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="68"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="321"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="662"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="759"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="813"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
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        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
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            <begin position="701"/>
            <end position="713"/>
        </location>
    </feature>
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        </location>
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            <begin position="822"/>
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        </location>
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    </feature>
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            <begin position="941"/>
            <end position="964"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA46029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1015" mass="109696" checksum="D2EE545825315FD5" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLF0</accession>
    <name>G4NLF0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_18090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721494.1">
        <property type="nucleotide sequence ID" value="XM_003721446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLF0"/>
    <dbReference type="GeneID" id="12986093"/>
    <dbReference type="KEGG" id="mgr:MGG_18090"/>
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    <dbReference type="HOGENOM" id="CLU_1107316_0_0_1"/>
    <dbReference type="InParanoid" id="G4NLF0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="251" mass="27024" checksum="B9DEA4833F06C405" modified="2011-12-14" version="1">MPQACTYCQRRPRAVPGDPFSPGQLLREPDSWIPPEPVSSDYKTRNALLHSSDDKMCALPKPSSGAFLTTACMARTGTRAAASTQGAVCPGMMLAWQLTHHVIAAGARASNTCCTRRSTCTPGKPGRYDSLVPRRQREKWRAPFRSRCTTGVHRRGRVEESLGGGGGGGATCGSSGTGKENLVAQRHEEDAGCSVRNVDPQAGRQEFITNEWYERKKHAFFAPLSRPRAGPTCRMLGVPADGENGGGFAMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLH6</accession>
    <name>G4NLH6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="3">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_18098</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="3"/>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721520.1">
        <property type="nucleotide sequence ID" value="XM_003721472.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4NLH6"/>
    <dbReference type="GeneID" id="12986110"/>
    <dbReference type="KEGG" id="mgr:MGG_18098"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_18098"/>
    <dbReference type="eggNOG" id="KOG0351">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001104_6_1_1"/>
    <dbReference type="InParanoid" id="G4NLH6"/>
    <dbReference type="OMA" id="MFRERSI"/>
    <dbReference type="OrthoDB" id="5244177at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022698">
        <property type="entry name" value="OrsD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF154">
        <property type="entry name" value="RECQ HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12013">
        <property type="entry name" value="OrsD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="1081"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="732"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="832"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="734"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="758"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="832"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA46777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1394" mass="158110" checksum="D416B35155D00F2F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLP5</accession>
    <name>G4NLP5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_12569</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720841.1">
        <property type="nucleotide sequence ID" value="XM_003720793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLP5"/>
    <dbReference type="SMR" id="G4NLP5"/>
    <dbReference type="STRING" id="242507.G4NLP5"/>
    <dbReference type="GeneID" id="2682441"/>
    <dbReference type="KEGG" id="mgr:MGG_12569"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12569"/>
    <dbReference type="eggNOG" id="KOG0867">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_3_2_1"/>
    <dbReference type="InParanoid" id="G4NLP5"/>
    <dbReference type="OMA" id="WICYAQG"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006414">
        <property type="term" value="P:translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03044">
        <property type="entry name" value="GST_N_EF1Bgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000142">
        <property type="entry name" value="Elongation factor 1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050802">
        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF10">
        <property type="entry name" value="ELONGATION FACTOR EEF-1B GAMMA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17120)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="91"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24140" checksum="52C0B36F6345FEEC" modified="2011-12-14" version="1">MVPFATTYSWPSDPRASRVHALGKLGGLEIVGAPDFQMGVTNKSEEFLAKFPLGKVPALETADGFRLAESGAMAYYAAAAGNKADQLLGTDAQTKAKIMEWAFFADSELSANCMPIFVMCVVKMYAPDENRYNSCITNIERALGKIEATLAKGNGKYLVGDKLTYADLMVFSPLFFAGGSVLDAEMRKSAPTVFSYLENLAAIPEIKETFGELKFVEKRVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLV8</accession>
    <name>G4NLV8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glucosamine 6-phosphate N-acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_02834</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="2.3.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acetyltransferase family. GNA1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.4" evidence="8"/>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720904.1">
        <property type="nucleotide sequence ID" value="XM_003720856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLV8"/>
    <dbReference type="SMR" id="G4NLV8"/>
    <dbReference type="FunCoup" id="G4NLV8">
        <property type="interactions" value="447"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NLV8"/>
    <dbReference type="GeneID" id="2682387"/>
    <dbReference type="KEGG" id="mgr:MGG_02834"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02834"/>
    <dbReference type="eggNOG" id="KOG3396">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072095_0_1_1"/>
    <dbReference type="InParanoid" id="G4NLV8"/>
    <dbReference type="OMA" id="NQRYDWI"/>
    <dbReference type="OrthoDB" id="10039976at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
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    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000048">
        <property type="entry name" value="Glucosamine 6-phosphate N-acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF11">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="9">
        <location>
            <begin position="39"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA46161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="184" mass="20233" checksum="2AEC656F316DE80A" modified="2011-12-14" version="1">MAILYSDASSQAGASSTDAGLFSLDLISPEVAVVLPEGYKMRSLRKSDYDSGYLDCLRVLTTVGEFDRSAFEVRFDEFAQSPGSYYILVVEDAEGRVVGTGALIVERKIIHSLASVGHIEDIAVAKDQQGKKLGLRIIQALDYISEKVGCYKSILDCSEKNEGFYDKCGFKRAGLQMAHYYDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4NLV9</accession>
    <name>G4NLV9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase-activating protein GYP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720905.1">
        <property type="nucleotide sequence ID" value="XM_003720857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NLV9"/>
    <dbReference type="SMR" id="G4NLV9"/>
    <dbReference type="FunCoup" id="G4NLV9">
        <property type="interactions" value="12"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NLV9"/>
    <dbReference type="GeneID" id="2682386"/>
    <dbReference type="KEGG" id="mgr:MGG_02833"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02833"/>
    <dbReference type="eggNOG" id="KOG4347">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003538_1_0_1"/>
    <dbReference type="InParanoid" id="G4NLV9"/>
    <dbReference type="OMA" id="IYMSETQ"/>
    <dbReference type="OrthoDB" id="17687at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000021">
        <property type="entry name" value="GTPase activating protein (Gyp2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000015">
        <property type="entry name" value="GTPase activating protein (Gyp2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="290"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="861"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="861"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="898"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1186" mass="130841" checksum="70BD58A7237AB5F6" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH91</accession>
    <name>G5EH91_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g1126</name>
        <name evidence="2" type="ORF">MGG_10346</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720470.1">
        <property type="nucleotide sequence ID" value="XM_003720422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH91"/>
    <dbReference type="GeneID" id="2681921"/>
    <dbReference type="KEGG" id="mgr:MGG_10346"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10346"/>
    <dbReference type="eggNOG" id="ENOG502RW0W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1129187_0_0_1"/>
    <dbReference type="OMA" id="WAVAFPM"/>
    <dbReference type="OrthoDB" id="3447349at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ71719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA45727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="261" mass="29203" checksum="46A1C08B7B46C5B4" modified="2011-12-14" version="1">MLKQFLEGGQARIKQTLQRGYAPAHFTHNLELILVEDSRSSTSLSMRSKLASTRDRIARLRTLDPVTLIWWAVAFPMRQWSGGRKMSSCTFAALVWRAPDFATEMKPLLGAVMDDLKMLAEVHRKSRAVQDLLLAVAMDPAPGSRSITQKTDAQLLQNEYVALTGAQPQFPAVLPHVLRQGIEASQKYQQERDKGLPLSTAIKVFIPTVPMGKDAYLMLSIGSTEVWGLLHELGIIDQTVREPRAGDTNDELLDQIELFQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHX5</accession>
    <name>G5EHX5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGCH7_ch7g704</name>
        <name evidence="2" type="ORF">MGG_17915</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15</strain>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="1" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">70-15</strain>
        </source>
    </reference>
    <reference evidence="2" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720777.1">
        <property type="nucleotide sequence ID" value="XM_003720729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHX5"/>
    <dbReference type="GeneID" id="12984788"/>
    <dbReference type="KEGG" id="mgr:MGG_17915"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17915"/>
    <dbReference type="HOGENOM" id="CLU_2184497_0_0_1"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EAQ71297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="109" mass="12271" checksum="C1B95DA2AD00706B" modified="2011-12-14" version="1">MDRAEIRHETKSRARPEGCKMVTGEKTPWYVLWGATTARLEMDQRIFHNGPFERPGRSIRLFSGVTLASIGCVQGKQESSNATPEYGLHLCLKIGCSNHQVDNWKPSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4C9</accession>
    <name>A0A151V4C9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">alpha-amylase</fullName>
            <ecNumber evidence="4">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_09164</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JH165175">
        <property type="protein sequence ID" value="KYQ30441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016845945.1">
        <property type="nucleotide sequence ID" value="XM_016990470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4C9"/>
    <dbReference type="SMR" id="A0A151V4C9"/>
    <dbReference type="STRING" id="242507.A0A151V4C9"/>
    <dbReference type="GeneID" id="2680119"/>
    <dbReference type="KEGG" id="mgr:MGG_09164"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09164"/>
    <dbReference type="eggNOG" id="KOG0471">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4C9"/>
    <dbReference type="OMA" id="QAFEWHT"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11318">
        <property type="entry name" value="AmyAc_bac_fung_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013776">
        <property type="entry name" value="A-amylase_thermo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006969">
        <property type="entry name" value="PRK09441.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001021">
        <property type="entry name" value="Alph-amls_thrmst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="11">
        <location>
            <begin position="35"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KYQ30441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="575" mass="64270" checksum="32474D772CEFE86B" modified="2016-06-08" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-06-08" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A151V4L3</accession>
    <name>A0A151V4L3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAP family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_10265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <dbReference type="EMBL" id="JH165178">
        <property type="protein sequence ID" value="KYQ30517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846021.1">
        <property type="nucleotide sequence ID" value="XM_016990512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A151V4L3"/>
    <dbReference type="FunCoup" id="A0A151V4L3">
        <property type="interactions" value="583"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A0A151V4L3"/>
    <dbReference type="GeneID" id="2681885"/>
    <dbReference type="KEGG" id="mgr:MGG_10265"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10265"/>
    <dbReference type="eggNOG" id="KOG1508">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A151V4L3"/>
    <dbReference type="OMA" id="FFSYRGR"/>
    <dbReference type="OrthoDB" id="19419at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="255"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KYQ30517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36812" checksum="98DEB6944C65E0B4" modified="2016-06-08" version="1">MSAPEDFTIDPQTVKELQLLEAALSDVDLEIAAKQYLMTRDIFASRRSTIAKIPAFWAVVFEHAQRDLEAAITADDTELLVKGLVDIEVARPGIPASATPSDCGKDKFGEPRSVAFRFHFKDNDWIADKVLEKHFHYRYAKDGTAGLVSEPVKINWKAGKDLTQGLTDAAYNLWVAQKGNAAQKLDAVLDKDARKARDAAAKQLPEYKALAAMLEDADKAEGAISFFNFFSYRGRWISEAESVEAKAELEAKRARAAAGQSTKEDDEDDEDEEDDFAEEDVETFPAGHEVATTISDEIYPSAIDYYMEDDAELSELDIEDDDSDEEDVEMS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2025-06-18" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>A4RGE6</accession>
    <accession>G4NEQ7</accession>
    <name>SIP5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Protein SIP5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">SIP5</name>
        <name type="ORF">MGG_00076</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May negatively regulate the SNF1 kinase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SIP5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719064.1">
        <property type="nucleotide sequence ID" value="XM_003719016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RGE6"/>
    <dbReference type="FunCoup" id="A4RGE6">
        <property type="interactions" value="41"/>
    </dbReference>
    <dbReference type="STRING" id="242507.A4RGE6"/>
    <dbReference type="EnsemblFungi" id="MGG_00076T0">
        <property type="protein sequence ID" value="MGG_00076T0"/>
        <property type="gene ID" value="MGG_00076"/>
    </dbReference>
    <dbReference type="GeneID" id="2675036"/>
    <dbReference type="KEGG" id="mgr:MGG_00076"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00076"/>
    <dbReference type="eggNOG" id="KOG2789">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009068_1_0_1"/>
    <dbReference type="InParanoid" id="A4RGE6"/>
    <dbReference type="OMA" id="CFLTYPP"/>
    <dbReference type="OrthoDB" id="21471at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd24139">
        <property type="entry name" value="SIP5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039301">
        <property type="entry name" value="Sip5/DA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31315">
        <property type="entry name" value="PROTEIN SIP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31315:SF1">
        <property type="entry name" value="PROTEIN SIP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000333437" description="Protein SIP5">
        <location>
            <begin position="1"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="367"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="549"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="374"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="479"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="549"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="575"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="613"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="674"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="697"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="743"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="798"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="819" mass="86831" checksum="E6C199244DCC8A72" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-07-27" modified="2025-02-05" version="94" xmlns="https://uniprot.org/uniprot">
    <accession>A4RQ11</accession>
    <accession>G4MP22</accession>
    <name>AMPP2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName>Probable Xaa-Pro aminopeptidase MGG_05684</fullName>
            <ecNumber>3.4.11.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Aminoacylproline aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Prolidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ORF">MGG_05684</name>
    </gene>
    <organism>
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.</text>
            <dbReference type="EC" id="3.4.11.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.9"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710583.1">
        <property type="nucleotide sequence ID" value="XM_003710535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4RQ11"/>
    <dbReference type="SMR" id="A4RQ11"/>
    <dbReference type="STRING" id="242507.A4RQ11"/>
    <dbReference type="EnsemblFungi" id="MGG_05684T0">
        <property type="protein sequence ID" value="MGG_05684T0"/>
        <property type="gene ID" value="MGG_05684"/>
    </dbReference>
    <dbReference type="GeneID" id="2675942"/>
    <dbReference type="KEGG" id="mgr:MGG_05684"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05684"/>
    <dbReference type="eggNOG" id="KOG2737">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017266_1_2_1"/>
    <dbReference type="InParanoid" id="A4RQ11"/>
    <dbReference type="OMA" id="YELRMIR"/>
    <dbReference type="OrthoDB" id="10261878at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF3">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE AN0832-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0031">Aminopeptidase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0482">Metalloprotease</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000411836" description="Probable Xaa-Pro aminopeptidase MGG_05684">
        <location>
            <begin position="1"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="526" mass="58488" checksum="829B0ECC1E2D0B46" modified="2007-05-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKM7</accession>
    <name>G4MKM7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711022.1">
        <property type="nucleotide sequence ID" value="XM_003710974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKM7"/>
    <dbReference type="GeneID" id="2677845"/>
    <dbReference type="KEGG" id="mgr:MGG_04394"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04394"/>
    <dbReference type="eggNOG" id="KOG1290">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_824049_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKM7"/>
    <dbReference type="OrthoDB" id="5979581at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="337" mass="37605" checksum="ACC87B073B67DE3A" modified="2011-12-14" version="1">MTQTKRPEEVTRILPKDCIFLGTQRGARILRTTGRDIVANRWATLKVVAARDSPEYEARPVIADDSDIAGSRLRKYWLDGPNGRDLCLVLPVLGPGLSRLCTPIFSRLKPEFSRLVSLQATQANAQLHSERSCHGEQAETIQAHGSQRSQPEWHEEAAQGHRMPMAVRVRPYVLGMFYKQDYPECNSERHPQKDKASGIYRFIPGQPFSYNRQRIQGIGPLHRGCEIGLDSILLPAQLGLPRLHGMGKGLADSQKSNPGPRRVAPVFSDATRTPVLIDEGPGDSPNQEKVHSTEMSSMPMCSVPLTQRITEKRMRVNETSLAEVFQFPGSPEKKVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML25</accession>
    <name>G4ML25_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_14266</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711064.1">
        <property type="nucleotide sequence ID" value="XM_003711016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML25"/>
    <dbReference type="SMR" id="G4ML25"/>
    <dbReference type="FunCoup" id="G4ML25">
        <property type="interactions" value="251"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4ML25"/>
    <dbReference type="GeneID" id="2678867"/>
    <dbReference type="KEGG" id="mgr:MGG_14266"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14266"/>
    <dbReference type="eggNOG" id="KOG0425">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030988_1_1_1"/>
    <dbReference type="InParanoid" id="G4ML25"/>
    <dbReference type="OMA" id="FQAHIKF"/>
    <dbReference type="OrthoDB" id="19692at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="13"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA58452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="260" mass="29283" checksum="F916FF32F3C915BE" modified="2011-12-14" version="1">MASSRSTAPGAAGAKQRLASEFASLLKEPWVHFHDPDMIAANLFHWRFGLVVTNPDSDFYEGYFKVDMSFPTDYPYSPPQFKFATSTGIFHPNVYPDGRTCISILHRPGEDLMSGEMASERWSPLQGVESVLRSVLLLLDDPEIGSPANVDASVTYRDDRARYKQRAREAVARSHKDKPEDFVMPESLEAAKPPPKADYDEDFFQPSDEGEFDFGGSDTDDEGDMEFEDEDEDDEDVKMDTEEKAERRQKKAEDSDDGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML96</accession>
    <name>G4ML96_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710238.1">
        <property type="nucleotide sequence ID" value="XM_003710190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML96"/>
    <dbReference type="GeneID" id="12985382"/>
    <dbReference type="KEGG" id="mgr:MGG_16343"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16343"/>
    <dbReference type="HOGENOM" id="CLU_2223760_0_0_1"/>
    <dbReference type="InParanoid" id="G4ML96"/>
    <dbReference type="OMA" id="DRVEKHG"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="106" mass="11832" checksum="4FB3508C2791C62D" modified="2011-12-14" version="1">MYGHGVVFVLQFQTLTICRQIEALHRTNSLAVSNIFSLKICIDRVEKHGNLLRRRNATSCTKIDSISPKLLGAFFGNIHLQVRPTGCRGVVMHQAVLLLAHEVIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLC7</accession>
    <name>G4MLC7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_13049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710269.1">
        <property type="nucleotide sequence ID" value="XM_003710221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLC7"/>
    <dbReference type="GeneID" id="5051463"/>
    <dbReference type="KEGG" id="mgr:MGG_13049"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13049"/>
    <dbReference type="HOGENOM" id="CLU_863498_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLC7"/>
    <dbReference type="OMA" id="MHISSWL"/>
    <dbReference type="OrthoDB" id="5243461at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465221" evidence="2">
        <location>
            <begin position="22"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="322" mass="35362" checksum="50C6756C2182E798" modified="2011-12-14" version="1">MHISSWLKFTLLAALGPQALAKIIADQGADKGTLGASGRPHILRDPLPGDDDSHGAGSPPPGVVVPRPHDTTTAPHPGTIHNKRTSEELRRFPELRENNLDEHGRELKWGEGKRLPPNLWPNSFLPQMGYRPEENKGGEKKEQAPSPSPRRGGQQSSFPKSPRSVEGRIAARANDPDAGKQGVDADGNPISKLGRVHRIQRGRRVSPRDEEPAVLEARARPVLTTEPKPKSPKAKKPKEPKEPKDENTTEEQQGDPRPRENNVYNCDGSFNKYAARGLEARTEPKYYDANADPSSRDKGVHMDDGSIAPHGRRVRSGKSCRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLG6</accession>
    <name>G4MLG6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_14426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711099.1">
        <property type="nucleotide sequence ID" value="XM_003711051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLG6"/>
    <dbReference type="GeneID" id="5051879"/>
    <dbReference type="KEGG" id="mgr:MGG_14426"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14426"/>
    <dbReference type="HOGENOM" id="CLU_1315607_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLG6"/>
    <dbReference type="OMA" id="ITKWRLV"/>
    <dbReference type="OrthoDB" id="4779809at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="209" mass="21738" checksum="0317BDC602681A0A" modified="2011-12-14" version="1">MPHHVSKMSDLMFPGLADRAAKNSQLRGAGASKSSPAAGPRSTGRVRTPLPDKGKPRSASGPASRVGKTKGKKRASVAAAPRPRPAAGVVRPRSCLGCLRSALAGKQGSGDLAVCRETSPPSGRCYKCASGHSCEEIPAPARPPAVRFLAAVAKGDKAAITKWRLVVKGVLEIWEEEKEGGGVAVAAMSAEEKKEEAKRAALQLVEVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLY7</accession>
    <name>G4MLY7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome P450 6j1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">MGG_11098</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708688.1">
        <property type="nucleotide sequence ID" value="XM_003708640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLY7"/>
    <dbReference type="SMR" id="G4MLY7"/>
    <dbReference type="STRING" id="242507.G4MLY7"/>
    <dbReference type="GeneID" id="2683622"/>
    <dbReference type="KEGG" id="mgr:MGG_11098"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11098"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_31_0_1"/>
    <dbReference type="InParanoid" id="G4MLY7"/>
    <dbReference type="OMA" id="HKNPAHW"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000090">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF87">
        <property type="entry name" value="CYTOCHROME P450 MONOOXYGENASE ALND-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="506"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EHA56076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="572" mass="63972" checksum="76E9DE1DD66D28D1" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM06</accession>
    <name>G4MM06_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aldo-keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_06784</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709503.1">
        <property type="nucleotide sequence ID" value="XM_003709455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM06"/>
    <dbReference type="SMR" id="G4MM06"/>
    <dbReference type="STRING" id="242507.G4MM06"/>
    <dbReference type="GeneID" id="2684957"/>
    <dbReference type="KEGG" id="mgr:MGG_06784"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06784"/>
    <dbReference type="eggNOG" id="KOG1577">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_0_0_1"/>
    <dbReference type="InParanoid" id="G4MM06"/>
    <dbReference type="OMA" id="RRYPETW"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA56891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="334" mass="37356" checksum="1B40E0BFDAF0B4C3" modified="2011-12-14" version="1">MSLPTHFPLNNGQKIPAVGLGTFQSEHDNSRVKQVVKTALEMGYRHIDGAHAYGNEKQIGEAIKESGIPREEIFVTSKLAQTWHEPGDVERGLDLSLRNLQLDYVDLYLMHFPHAYKAGENNETIRHPSGNGKPVIDYDLSRRYPETWQAMERLVDSGKAKAIGVCNFNVLKTKRILEIARIIPAVNQVELHPYLPQHELMEFSAKHGILLMAHQPLGGRPVPAVRGHPDQSPPTEDQTIVDVASSCGMSPAQVCLSWLIQKGIPVIPKSNQREHLRSNMQVRKLSVELFNLVDGLAALRLGGPVRFLDPSRHVGFEIFDEENDQPIEDAAAWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN45</accession>
    <name>G4MN45_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_13127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710471.1">
        <property type="nucleotide sequence ID" value="XM_003710423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN45"/>
    <dbReference type="GeneID" id="5051527"/>
    <dbReference type="KEGG" id="mgr:MGG_13127"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13127"/>
    <dbReference type="eggNOG" id="ENOG502S3SW">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082473_2_0_1"/>
    <dbReference type="InParanoid" id="G4MN45"/>
    <dbReference type="OMA" id="LHEAVNW"/>
    <dbReference type="OrthoDB" id="5422293at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="289" mass="33835" checksum="8F3CDEE0369FF08E" modified="2011-12-14" version="1">MKHAPMKNTLEKDFIDRCLYKLPPKHRRRLMRMRMRLRQSWTPLELRRTVRILRVVHDEGYHQSCPTARAMLHLGGLLFRLPWHLPCHLPPPPGEIMAFPDGAREYFKTLHTALLAERLLPLWRWRDTAARSFFRLYEGICCGDDVMVQYETEYFWYRDEPSWAPDALPDPRGLGELAPGDEGRRQLAVLASTADALAEAFNWRHMHGLRRDRNHVDWLGDAPRVHEVVYKGPAWAEAVPRLPELLELHKASPEWLATGQDYRLGYSKDVICPFWKRNIFVETGALRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN71</accession>
    <name>G4MN71_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_05612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710497.1">
        <property type="nucleotide sequence ID" value="XM_003710449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN71"/>
    <dbReference type="GeneID" id="2675888"/>
    <dbReference type="KEGG" id="mgr:MGG_05612"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05612"/>
    <dbReference type="HOGENOM" id="CLU_2197472_0_0_1"/>
    <dbReference type="InParanoid" id="G4MN71"/>
    <dbReference type="OMA" id="PRWHELH"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA57885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="108" mass="12328" checksum="2E584857C0D6EEFE" modified="2011-12-14" version="1">MNRSCEKAMRILSEWVDDGPRWHELHELHEVAIGPPKDPRCIRSPCYGAGWMAVSTTWFWDKGKIADSTIESHMLVSWTSHPATAYRLLSGRNPQERELRGGRQAPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>G4MN77</accession>
    <name>G4MN77_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_16021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708812.1">
        <property type="nucleotide sequence ID" value="XM_003708764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MN77"/>
    <dbReference type="SMR" id="G4MN77"/>
    <dbReference type="GeneID" id="12985687"/>
    <dbReference type="KEGG" id="mgr:MGG_16021"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16021"/>
    <dbReference type="eggNOG" id="ENOG502RNBT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_927723_0_0_1"/>
    <dbReference type="InParanoid" id="G4MN77"/>
    <dbReference type="OrthoDB" id="10441495at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="274"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="300" mass="33910" checksum="0D970EDEFC042BEB" modified="2011-12-14" version="1">MEDMGTRFLQDRVRAAKAKADALKAELLQAEHESAHLASEIEKAERRAFLEEEKNERETQTRNSIRKFLQEAKLPQKLPPRSFRREANRIAEYWENHGLESGLTFTSLMCLCQALPKTDWSLLEKYPDTFQELSSMVNRRFQFSWEMWAWYCKFLDPARVESCAFGAVYDAFKHDVPGLCAKLQRLHSKGLIGTEIYEPPSSSTHLAFPGATGADDGTLDCRPKLNQGLKRKELGSGGPLRSLVCGNQIVSCDEPQSDQKKFTEAAADGGRQATRLQQSPCKRTAPQPQRHTLAHFPGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNR1</accession>
    <name>G4MNR1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003708889.1">
        <property type="nucleotide sequence ID" value="XM_003708841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNR1"/>
    <dbReference type="STRING" id="242507.G4MNR1"/>
    <dbReference type="GeneID" id="2681209"/>
    <dbReference type="KEGG" id="mgr:MGG_02118"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02118"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028281_6_1_1"/>
    <dbReference type="InParanoid" id="G4MNR1"/>
    <dbReference type="OMA" id="VAMRIMA"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465888" description="SET domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="123"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="425" mass="46459" checksum="3F4BC616AFE32FA1" modified="2011-12-14" version="1">MALLKQLVTLGAALASTAFAGNSGNKASVAAEHVLPQVPEYLSNITERALFHPKGWYDPKICTGDDDKWCLFTSRDVANGRGLAVISMPSNFQKIRHLEVIMNKAQTKASGLLREEEVGPGRIGIVATEQIKRATKLMELPPVLMIHKTFLNETDESTQEHMISAALSLLPEKTRALVEAAAGKSHLAVKSDVSSSSSRSRIAAILRAHPLEASTGATHWDGPEHGRHLALYPEVVALAHDCRPNAAFYVDHTDHSLHVTAARRMQAGEPLSISYVNPRLGRAEREAAARRMWGRPCGCAACTGRGGNLQALAGADARAAELAGMEAELRDADSAAVTEEMLQRYVRLMEQDGLQSRMADAYEQVAYNYGYLGLEERARRFGNLAIQAATIEQGRDSNDVTALRVFVNGVTEHYSWRWKIKRRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MNY0</accession>
    <name>G4MNY0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_06994</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709749.1">
        <property type="nucleotide sequence ID" value="XM_003709701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MNY0"/>
    <dbReference type="SMR" id="G4MNY0"/>
    <dbReference type="GeneID" id="2685167"/>
    <dbReference type="KEGG" id="mgr:MGG_06994"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06994"/>
    <dbReference type="eggNOG" id="ENOG502T4AX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_182417_0_0_1"/>
    <dbReference type="InParanoid" id="G4MNY0"/>
    <dbReference type="OMA" id="WYIHFAT"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA57137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="89" mass="9606" checksum="9D6312B3F2032BB8" modified="2011-12-14" version="1">MASPAPSATPAPGQFDWFRSIGATPEAVAVLNDQPILFTILLVVLVAIILQITLIWYIHYATMKPEQKKKKDTKKPAAGKPGAKPPAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4MQB2</accession>
    <name>G4MQB2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_09276</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709917.1">
        <property type="nucleotide sequence ID" value="XM_003709869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MQB2"/>
    <dbReference type="FunCoup" id="G4MQB2">
        <property type="interactions" value="197"/>
    </dbReference>
    <dbReference type="GeneID" id="2680199"/>
    <dbReference type="KEGG" id="mgr:MGG_09276"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09276"/>
    <dbReference type="eggNOG" id="ENOG502QRSG">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006524_0_0_1"/>
    <dbReference type="InParanoid" id="G4MQB2"/>
    <dbReference type="OMA" id="IYMHEIG"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051089">
        <property type="entry name" value="prtT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31845:SF39">
        <property type="entry name" value="TRANSCRIPTION FACTOR PBCR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="93"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="161"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="252"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="430"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="738"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="836"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA57305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="971" mass="103974" checksum="7B5A3B4693977B96" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MRX2</accession>
    <name>G4MRX2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_02459</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709253.1">
        <property type="nucleotide sequence ID" value="XM_003709205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MRX2"/>
    <dbReference type="SMR" id="G4MRX2"/>
    <dbReference type="FunCoup" id="G4MRX2">
        <property type="interactions" value="869"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MRX2"/>
    <dbReference type="GeneID" id="2681556"/>
    <dbReference type="KEGG" id="mgr:MGG_02459"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02459"/>
    <dbReference type="eggNOG" id="KOG2732">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021763_1_0_1"/>
    <dbReference type="InParanoid" id="G4MRX2"/>
    <dbReference type="OMA" id="HCILIGT"/>
    <dbReference type="OrthoDB" id="3763at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07387">
        <property type="entry name" value="MPP_PolD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.430:FF:000002">
        <property type="entry name" value="DNA polymerase delta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.50:FF:000006">
        <property type="entry name" value="DNA polymerase delta subunit 2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040663">
        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041863">
        <property type="entry name" value="PolD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18018">
        <property type="entry name" value="DNA_pol_D_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="12">
        <location>
            <begin position="49"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="11">
        <location>
            <begin position="223"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA56641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="497" mass="54898" checksum="71B6EB38EF97C812" modified="2011-12-14" version="1">MVKLEDVSSSLLQKPSNSNDSEIPLERRQSSYKSLKTFALDKEKQYQQQYGDMYFLRLTKIKPAVEEIASTAFGDLVIGGEPARQVPRVLDVRQGELCWVAGTVYMDMPLKPSILEDVAKDRWISAPTSVQKYFSKDGRDSILLEDDSGRVRLVGDILKSVVLVTGCIIAVMGTENASGEFEVIDLKFPDLAPQPERWSLSKPADDDVEMGNGGYSSNRGKTAILSGLNFSSTDTSYAMELNLLLEYLLGDALDPIAQKDISQISRLIVAGDSISPDTGKPAAEEEVAGKKVHKKYGYDASSYNPIPSQLLDEFLSELLPTIPVTFLPGAHDPANASYPQQPIHPAMFTKSRTYSALPGPTAEPGWFDTVTNPWEGEVEGWRVLGTSGQNVDDVFKYVDSDDRLGMMEAMCRWRCSAPTAPDTLWSYPFQDDDPFVMNQCPHLYFVGNQPEFGTKTITGTEGQEVRLITVPTFSASRELVLVDNETLEVTRVKISAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4MS41</accession>
    <name>G4MS41_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710119.1">
        <property type="nucleotide sequence ID" value="XM_003710071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MS41"/>
    <dbReference type="GeneID" id="12985339"/>
    <dbReference type="KEGG" id="mgr:MGG_16311"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16311"/>
    <dbReference type="HOGENOM" id="CLU_1865491_0_0_1"/>
    <dbReference type="InParanoid" id="G4MS41"/>
    <dbReference type="OMA" id="QNWVFAD"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="137" mass="14587" checksum="4CF4003A813CF4FC" modified="2011-12-14" version="1">MPCSSCKARGHSCRMISSNSRCSGLPFAYGLFRNLTWSPKRLFQSRSEAEAVRLDAELSVKDAVERDRLGVDELPFDGPSKSGLVPELRSLGHVDVVDWSSVLGADPQNWVFADLAPGNDPTPGSIDGVVPGNSGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MSZ6</accession>
    <name>G4MSZ6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714462.1">
        <property type="nucleotide sequence ID" value="XM_003714414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MSZ6"/>
    <dbReference type="GeneID" id="12984667"/>
    <dbReference type="KEGG" id="mgr:MGG_15713"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15713"/>
    <dbReference type="HOGENOM" id="CLU_2441275_0_0_1"/>
    <dbReference type="InParanoid" id="G4MSZ6"/>
    <dbReference type="OMA" id="MHTWAMR"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="90" mass="9783" checksum="E14566F435BA7553" modified="2011-12-14" version="1">MHTWAMRNPGGPALLGASFGKDNATVPETDSSSARSTGAESKTKADEKIHLQFRGRHVTILCNPRPQHLPNNRRLGYDKTKKDRGNGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4MT63</accession>
    <name>G4MT63_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_15861</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715334.1">
        <property type="nucleotide sequence ID" value="XM_003715286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MT63"/>
    <dbReference type="SMR" id="G4MT63"/>
    <dbReference type="STRING" id="242507.G4MT63"/>
    <dbReference type="GeneID" id="12985628"/>
    <dbReference type="KEGG" id="mgr:MGG_15861"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15861"/>
    <dbReference type="eggNOG" id="KOG1721">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014245_2_0_1"/>
    <dbReference type="InParanoid" id="G4MT63"/>
    <dbReference type="OMA" id="VAMQPLY"/>
    <dbReference type="OrthoDB" id="9439903at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF12">
        <property type="entry name" value="RFEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="211"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="371"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="48"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA55527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="478" mass="52153" checksum="324C959CA95D1A11" modified="2011-12-14" version="1">MDNSQYSANVVNTTTTASYPSPSATLNGLQNQQQNHSGQPQTLPPLQPQTHSMQQPQQQQQHQQQQAQQQQHQQQQQQQQQQQQASPYGSYHNTPRTTATPNPSGTPTMSNYPPPPGQQNVARAPYPGMMPAPQYQQPHPGYPTTTSMMTQASTAMAHPQPIAPAPPGGRAPPVLRPMPAGGMVPQGGMSSPYAQSPLMPQPQMMQQEGDAPTHVVGSQGRRGILPSAPGRPQAPVAGSQAAKNQIPQKDADGKFPCPHCNKTYLHAKHLKRHLLRHTGDRPYMCVLCRDTFSRSDILKRHFQKCSIRRGNPTGASHLSHPHAHVKKNQAAQQKAMGNENELNPINGMGNMGPDGMVHPFGLIPAQDGMPNMSNDQNHLSRQPSMNRMEDPNDRDRRSVTGSVMGNNTRPGSFDQGYNGTVPHTMAANINPQLANYPMPPNQNGMPMFAGQASNQQSGGLDWSQMFQADADRNHQARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTH9</accession>
    <name>G4MTH9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714537.1">
        <property type="nucleotide sequence ID" value="XM_003714489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTH9"/>
    <dbReference type="SMR" id="G4MTH9"/>
    <dbReference type="FunCoup" id="G4MTH9">
        <property type="interactions" value="81"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MTH9"/>
    <dbReference type="GeneID" id="2679508"/>
    <dbReference type="KEGG" id="mgr:MGG_01562"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01562"/>
    <dbReference type="eggNOG" id="ENOG502S3Z9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065203_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTH9"/>
    <dbReference type="OMA" id="WNLGPPP"/>
    <dbReference type="OrthoDB" id="5223508at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd23703">
        <property type="entry name" value="mS26_PET12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058940">
        <property type="entry name" value="mS26_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26163">
        <property type="entry name" value="mS26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="323" mass="36941" checksum="4F8304E12C3D7421" modified="2011-12-14" version="1">MPPPMPLGGQGLALRPATVSALRCAATSSTRQFTTSRPHQKVMIPPESPKFINLPEPPQSKVLPRVRNKGKLPVPRQVFDLRRRAPGLPSHGRRDPRLQEGYVDTVMPKSKAELEGEGKARTPLQQWRRQLTDNRRAALEEGLKGLFQRQLKKDRFERREKARLHRENVDALHAPERRDDFLNRSTIRADTISTKVELDPLRHERAAESAKRTAAVLQARAERRRDHLQALYMAAKDFIVTEEELAQHIEFLFSPENPANSHKDPNTGATAENIWQLKGKPFRVSERMTQFARTSNDDSRNSNETRETHRQKYVAEELTGGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MTZ2</accession>
    <name>G4MTZ2_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_01609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714593.1">
        <property type="nucleotide sequence ID" value="XM_003714545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MTZ2"/>
    <dbReference type="SMR" id="G4MTZ2"/>
    <dbReference type="STRING" id="242507.G4MTZ2"/>
    <dbReference type="GeneID" id="2679310"/>
    <dbReference type="KEGG" id="mgr:MGG_01609"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01609"/>
    <dbReference type="eggNOG" id="ENOG502SFMK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096545_0_0_1"/>
    <dbReference type="InParanoid" id="G4MTZ2"/>
    <dbReference type="OMA" id="CCIAGCF"/>
    <dbReference type="OrthoDB" id="5597238at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466131" evidence="2">
        <location>
            <begin position="18"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA54786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="182" mass="18090" checksum="DD0A969265A3574A" modified="2011-12-14" version="1">MRFSVILTGAFAAVAMAQSTTPTTASAPTPVGLTPQQSSALACLEKCNPSDVNCRAACNGVPFPNDGQVNTTNQCVADCSKQYGNGTEADNARFIKCSDDCINKNYWNPSSGTPNPTGNSGSSSSNGNGNSNGNSGSKTTGGSNPTNTGSSSSATGSSAADALRIGSSIAGVVGFMAALLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="70" xmlns="https://uniprot.org/uniprot">
    <accession>G4MUD6</accession>
    <name>G4MUD6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MGG_11174</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714630.1">
        <property type="nucleotide sequence ID" value="XM_003714582.1"/>
    </dbReference>
    <dbReference type="SMR" id="G4MUD6"/>
    <dbReference type="STRING" id="242507.G4MUD6"/>
    <dbReference type="GeneID" id="2679285"/>
    <dbReference type="KEGG" id="mgr:MGG_11174"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11174"/>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_3_2_1"/>
    <dbReference type="InParanoid" id="G4MUD6"/>
    <dbReference type="OMA" id="CLAAQMD"/>
    <dbReference type="OrthoDB" id="10266508at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000001">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
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        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="3"/>
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        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
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        <property type="match status" value="3"/>
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    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
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        <property type="entry name" value="CheY-like_superfamily"/>
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    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
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    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
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    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
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    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
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    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
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        <property type="entry name" value="HisK_dim/P_sf"/>
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        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
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    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
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    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
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        <property type="entry name" value="BCTRLSENSOR"/>
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        <property type="entry name" value="HATPase_c"/>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
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    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
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        <property type="entry name" value="CheY-like"/>
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        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
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        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="2"/>
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        <property type="match status" value="6"/>
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        <property type="entry name" value="HIS_KIN"/>
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    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="196"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
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        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="383"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="475"/>
            <end position="527"/>
        </location>
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    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="567"/>
            <end position="619"/>
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    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="659"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="733"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="1104"/>
            <end position="1223"/>
        </location>
    </feature>
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        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="71"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1244"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1268"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1297"/>
            <end position="1307"/>
        </location>
    </feature>
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        <location>
            <position position="1153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA54823.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1307" mass="142944" checksum="F95F65A31D26FA82" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVC7</accession>
    <name>G4MVC7_PYRO7</name>
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        <recommendedName>
            <fullName evidence="4">Ubiquitin carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_11148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714756.1">
        <property type="nucleotide sequence ID" value="XM_003714708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVC7"/>
    <dbReference type="STRING" id="242507.G4MVC7"/>
    <dbReference type="GeneID" id="5051123"/>
    <dbReference type="KEGG" id="mgr:MGG_11148"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11148"/>
    <dbReference type="eggNOG" id="ENOG502SERQ">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038857_1_0_1"/>
    <dbReference type="InParanoid" id="G4MVC7"/>
    <dbReference type="OMA" id="YQRIPGF"/>
    <dbReference type="OrthoDB" id="2896006at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA54949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="38542" checksum="37578F5ACD33B297" modified="2011-12-14" version="1">MLDTIRTTLGSDLSKRWMQEQVPKLPPISPWLKGAFAFDFFIFLPLLLFANYTLASVFTTLAVVENPDSAPSYAALAAHDEEDGFAPAATQPLRKKPDVNSPLALAGVVTSSMRATFRHLYSTGGVRMFVRGMVCAWAIFVADTFIGGIFLAIPFVFPFGRLAAYLALCQLHTAWVHIVISDRPRGSLAFWRRLPPFGKTFNATKYAVGLFWLADTFTGTTPYVIGTFMGDDGKMSGKTVFALLVFTTLMLIVRLPAFVALTLVQASLLPEEEGTVVPFDRSFGGRVGPSELGGAEYLSVRDAIRSLNRESWVRIIKMFLKTFLVIVALMIVISLVVAVQVVVLQPHGGKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MVG0</accession>
    <name>G4MVG0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_12415</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715593.1">
        <property type="nucleotide sequence ID" value="XM_003715545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MVG0"/>
    <dbReference type="SMR" id="G4MVG0"/>
    <dbReference type="STRING" id="242507.G4MVG0"/>
    <dbReference type="CAZy" id="CBM18">
        <property type="family name" value="Carbohydrate-Binding Module Family 18"/>
    </dbReference>
    <dbReference type="GeneID" id="2683072"/>
    <dbReference type="KEGG" id="mgr:MGG_12415"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12415"/>
    <dbReference type="eggNOG" id="ENOG502T53Q">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_983783_0_0_1"/>
    <dbReference type="InParanoid" id="G4MVG0"/>
    <dbReference type="OMA" id="GSQTMCG"/>
    <dbReference type="OrthoDB" id="5242494at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466193" description="Chitin-binding type-1 domain-containing protein" evidence="9">
        <location>
            <begin position="18"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="10">
        <location>
            <begin position="94"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA55786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="260" mass="25260" checksum="F5D275F9D86789D8" modified="2011-12-14" version="1">MRSALFFFAAIAARALAQSNSTLAISQDATCGSNVMLTCQGSAFGNCCSRNGYCGSAYDYCGTGCQAGFGSCGLNSTGTNSNPNFNSAQQVSLDGTCGDGITCQGSSFGSCCSASGYCGSSDAYCGADCQPDSGICGGPIVGTATATTAIPLPAPTSTSAANSTVIGNATTTANTCPAGVCTVSRASILSGDIYLACGGSASVQGSCLCVLPKGSAASEGASGTCATCVSAGNFCLTSDQCCGGKRCVPVIPRATSGTCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MX45</accession>
    <name>G4MX45_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">U1 zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_07998</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714950.1">
        <property type="nucleotide sequence ID" value="XM_003714902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MX45"/>
    <dbReference type="SMR" id="G4MX45"/>
    <dbReference type="STRING" id="242507.G4MX45"/>
    <dbReference type="GeneID" id="2678383"/>
    <dbReference type="KEGG" id="mgr:MGG_07998"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07998"/>
    <dbReference type="eggNOG" id="KOG0150">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051534_0_0_1"/>
    <dbReference type="InParanoid" id="G4MX45"/>
    <dbReference type="OMA" id="KSAPRYW"/>
    <dbReference type="OrthoDB" id="191651at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040023">
        <property type="entry name" value="WBP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13173">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13173:SF10">
        <property type="entry name" value="WW DOMAIN-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-C C2H2-type zinc finger" evidence="5">
        <location>
            <begin position="9"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="29"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="209"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="247"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="263"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA55143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="291" mass="32441" checksum="8C98EC7271E8A36F" modified="2011-12-14" version="1">MAEYWKSTPRYWCKHCSMYVRDTKLERTNHEATGKHRGAVERALRDLHRGHEKQEREKERARREIERLNGVVTGGEGDNKYKSGRSAPPGRGPPQEASSSSGKEQRQAQLEQLAGMGVNIPDELRGQLAMAGEWTVTKTRVIDDGEGNESVARGVRKRELEKTEEEKEEENAVNGLFKKPRRWGMDTRIAGGDDGGELDALLSGSSFVVKGEKKEEDEEEAAKPPLKVEDTEKGPDLEGAPQQEKPNVVKEEEDVVKKEPADEASAPHTAAEAAAPAVVFKKRKPKNIRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXD3</accession>
    <name>G4MXD3_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713270.1">
        <property type="nucleotide sequence ID" value="XM_003713222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXD3"/>
    <dbReference type="STRING" id="242507.G4MXD3"/>
    <dbReference type="GeneID" id="12986174"/>
    <dbReference type="KEGG" id="mgr:MGG_15490"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15490"/>
    <dbReference type="eggNOG" id="ENOG502QQMC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1185205_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXD3"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA53463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="234" mass="26327" checksum="D854E921A8E1DFFC" modified="2011-12-14" version="1">MTTSGAVVDAVIRKARALTEKQRGQDSLDIFNQLFRYILGDKLHTDVIEFGEEQHVLDVGCGSGLWPILMAQQLETILAPMHLNSPNLPSILAAYRHIILPEKMKKGSIKSWSTLYGKIATHLKHGTGVFEQFEIDWKFKRNSDPIPEALEKWSTKLHHAMEDHGMSIQCDPEETRSMLLNNGFNDVQERAILLPVNDWQSKDADKKIGRWFNTALTESITLGPTSPTPLKSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXV4</accession>
    <name>G4MXV4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome P450 52A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_12496</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715851.1">
        <property type="nucleotide sequence ID" value="XM_003715803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXV4"/>
    <dbReference type="SMR" id="G4MXV4"/>
    <dbReference type="STRING" id="242507.G4MXV4"/>
    <dbReference type="GeneID" id="5051088"/>
    <dbReference type="KEGG" id="mgr:MGG_12496"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12496"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_27_0_1"/>
    <dbReference type="InParanoid" id="G4MXV4"/>
    <dbReference type="OMA" id="VMQTYAI"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF5">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA56044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="511" mass="58409" checksum="926F149D384317BB" modified="2011-12-14" version="1">MIQKYGGHAVKFSFSNSPLDNIFGLRFAWEFYRHGRRDEYLKFTHRSFAQSGAGRANPYTYEVNLGGVRTIWTADPENIKAMLGSQFEDYGRGKAFQSRWHDLLGTGIFNADGREWHDSRHRLRPLFNRQRVSNLDSFERQIQIMINRHLGGGRTVDLKDVISRFALDAIGDYAMGFQVNALADRKNDFLDALERIKTIQNIKECAGPLSWLVPTPGFKRDLKVLDDFMEPLIEHAASLPQSVLDEMEKTDHGWTYVKACASVSRDRHFLKYELMSVILAGRDTVSGTLVWTFLELVKRPDLMADLRREIENTVGIGRDAPRPTHDDLRSMRLVKNTLNETLRLYPTVSLNLRTALRDTSLPRGNDHDGNKPVGLAEGTPVIFSSHILQLSPETYEQSPPGTSPPHVFDPYRWEEWKPKPWTYIPFGGGPRICIGQEFALAEMAFLLVRLLQNYSRLEMRCEMRGNSDEGWERPNGSASIVEQFMMEKGRVRISGDVTLSPRDKVLMAFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXX3</accession>
    <name>G4MXX3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA56063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715870.1">
        <property type="nucleotide sequence ID" value="XM_003715822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXX3"/>
    <dbReference type="STRING" id="242507.G4MXX3"/>
    <dbReference type="GeneID" id="12986806"/>
    <dbReference type="KEGG" id="mgr:MGG_15980"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15980"/>
    <dbReference type="HOGENOM" id="CLU_1993060_0_0_1"/>
    <dbReference type="InParanoid" id="G4MXX3"/>
    <dbReference type="OrthoDB" id="5095609at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA56063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="125" mass="13959" checksum="80310CFF0FB91A04" modified="2011-12-14" version="1">MWSSTLCKGALRKYTARHNQIKRACIKSLASRPELNVESEPDLRGVNPNQHPDLDPDPDPDPNPNRNGPNGPGSLITTPIRSGARTYRNGLRADFAVINGISKYYYDVQIVAINKIPLIRARLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MXY7</accession>
    <name>G4MXY7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MGG_10869</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713322.1">
        <property type="nucleotide sequence ID" value="XM_003713274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MXY7"/>
    <dbReference type="SMR" id="G4MXY7"/>
    <dbReference type="GeneID" id="2676383"/>
    <dbReference type="KEGG" id="mgr:MGG_10869"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10869"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_22_1_1"/>
    <dbReference type="InParanoid" id="G4MXY7"/>
    <dbReference type="OMA" id="GCSFQHG"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF12">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA53515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="54777" checksum="C2E0A95127F1B86E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYI6</accession>
    <name>G4MYI6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cystathionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Gamma-cystathionase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MGG_10380</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713413.1">
        <property type="nucleotide sequence ID" value="XM_003713365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYI6"/>
    <dbReference type="SMR" id="G4MYI6"/>
    <dbReference type="FunCoup" id="G4MYI6">
        <property type="interactions" value="483"/>
    </dbReference>
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    <dbReference type="KEGG" id="mgr:MGG_10380"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10380"/>
    <dbReference type="eggNOG" id="KOG0053">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_3_1"/>
    <dbReference type="InParanoid" id="G4MYI6"/>
    <dbReference type="OMA" id="YKQDGVG"/>
    <dbReference type="OrthoDB" id="3512640at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004123">
        <property type="term" value="F:cystathionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000043">
        <property type="entry name" value="Cystathionine gamma-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000008">
        <property type="entry name" value="Cystathionine gamma-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF15">
        <property type="entry name" value="CYSTATHIONINE GAMMA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EHA53606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="426" mass="45173" checksum="45C8F300185E557B" modified="2011-12-14" version="1">MTASNLHEQAPAVAAVAHQQQQQQQQSSRGFATRAVHAGSSPDPTTGAVIPAISLSTTFRQSAPSQPVGLYEYSRSANPNRDNFEEAVASLENARHGFAFSSGSATTAVVLQSLASGSHVISVSDVYGGTHRYFTQVAQAHNIEVTFSHDIVADVGSQIRPDTKLIWIESPSNPTLSLVDIRAVADAAHARGVLVVVDNTFLSPYIQNPLNLGADIVVHSVTKYINGHSDVVMGVAACNDDALASRLRFLQNAIGAVPSAFDSWLAHRGLKTLHLRAREASRNAAAVAAFLETSPYVISVNYPGLESHPQRDIARRQHRDGMGGGMLSFRVKGGLVAADSFCSTTRVFTLAESLGGVESLVELPSVMTHAGIPRQSREAVGIYDDLIRISCGIEEAEDLVADVRQALEAAALASKLHSSSGNGNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4MYQ8</accession>
    <name>G4MYQ8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ER-derived vesicles protein ERV14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_08132</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cornichon family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715094.1">
        <property type="nucleotide sequence ID" value="XM_003715046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MYQ8"/>
    <dbReference type="SMR" id="G4MYQ8"/>
    <dbReference type="FunCoup" id="G4MYQ8">
        <property type="interactions" value="839"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MYQ8"/>
    <dbReference type="GeneID" id="2678327"/>
    <dbReference type="KEGG" id="mgr:MGG_08132"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08132"/>
    <dbReference type="eggNOG" id="KOG2729">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_112942_0_0_1"/>
    <dbReference type="InParanoid" id="G4MYQ8"/>
    <dbReference type="OMA" id="HKKECFI"/>
    <dbReference type="OrthoDB" id="434393at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003377">
        <property type="entry name" value="Cornichon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033466">
        <property type="entry name" value="Cornichon_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03311">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01398">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01340">
        <property type="entry name" value="CORNICHON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA55287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="16168" checksum="5E4FAE5612083602" modified="2011-12-14" version="1">MSGEAWLYLFAVLVNAVNLFLQVFFTIMYSDLECDYINPIDLCNRLNTYIIPEAAVHGFLTFIFLINGYWLPLILNLPLLGWNIKKIVDNAHLLDATEIFRKLNVHKKESFIKLGFHLIMFFFYLYSMIVALIKDESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ48</accession>
    <name>G4MZ48_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_01382</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA54515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003714274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ48"/>
    <dbReference type="SMR" id="G4MZ48"/>
    <dbReference type="GeneID" id="2679075"/>
    <dbReference type="KEGG" id="mgr:MGG_01382"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01382"/>
    <dbReference type="eggNOG" id="KOG1611">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_9_1_1"/>
    <dbReference type="InParanoid" id="G4MZ48"/>
    <dbReference type="OMA" id="TFWDWRG"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF7">
        <property type="entry name" value="NADB-LER2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA54515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="262" mass="28760" checksum="D991378773A366AD" modified="2011-12-14" version="1">MTCNYGSYKSGSTVARKPLPLTILIIGGNRGIGLAFVRQYVALGFNVYTTYRKCSESEALELFALEAKNPNNLKVMTLDLADEDSINQAAEDFDGKQLDVLINCGAVCELNRPALETTADELMSRFRINCVGPFLTTRAFLPHLKRSRNLTGGDRSPLVVNMTSEMASLTENRPGNRPGTCLSYRASKAALNMTTVTLARELEDEGVACVALSPGRCVTKMAKWRGLMDPAESVEVMVDVIDSLRFDDSAKFLNFDGRPIAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZ88</accession>
    <name>G4MZ88_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ser/arg-related nuclear matrix protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_08192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715168.1">
        <property type="nucleotide sequence ID" value="XM_003715120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZ88"/>
    <dbReference type="STRING" id="242507.G4MZ88"/>
    <dbReference type="GeneID" id="2678427"/>
    <dbReference type="KEGG" id="mgr:MGG_08192"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08192"/>
    <dbReference type="eggNOG" id="ENOG502SJTA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010037_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZ88"/>
    <dbReference type="OMA" id="GYQDWYT"/>
    <dbReference type="OrthoDB" id="5296at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1038" mass="119110" checksum="D33D8061DB7A9E81" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZE7</accession>
    <name>G4MZE7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Beta-xylosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA53702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713509.1">
        <property type="nucleotide sequence ID" value="XM_003713461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZE7"/>
    <dbReference type="STRING" id="242507.G4MZE7"/>
    <dbReference type="GeneID" id="2677806"/>
    <dbReference type="KEGG" id="mgr:MGG_04411"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04411"/>
    <dbReference type="eggNOG" id="ENOG502STXT">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095402_0_1_1"/>
    <dbReference type="InParanoid" id="G4MZE7"/>
    <dbReference type="OMA" id="HPHFPRT"/>
    <dbReference type="OrthoDB" id="4156665at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="23842" checksum="057EEAA2DEB1A352" modified="2011-12-14" version="1">MYHRGHDQQRKMSRQASRQLSQSAIPPMSPLEQVVDQQQQQQQQQSQQSSSSPSSPTSIPTSSFPCPSATALGQRRAARNPALAQKLAQMALPLAPLVQLTTGQIHPAFPATLLSFWLLTDDELESLASFYHQRTPSNLSRFYPCPVSWSSDLPLEEKRRKLGKFIGLRGCETPTHHVVLARSAEDLMDEARRNAGAEDDGDEALRRKFGFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZG7</accession>
    <name>G4MZG7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS hexose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_01390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
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        <property type="protein sequence ID" value="EHA54526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003714333.1">
        <property type="nucleotide sequence ID" value="XM_003714285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZG7"/>
    <dbReference type="SMR" id="G4MZG7"/>
    <dbReference type="GeneID" id="2679132"/>
    <dbReference type="KEGG" id="mgr:MGG_01390"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01390"/>
    <dbReference type="eggNOG" id="KOG0254">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_30_13_1"/>
    <dbReference type="InParanoid" id="G4MZG7"/>
    <dbReference type="OMA" id="STSEQWR"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000090">
        <property type="entry name" value="MFS sugar transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF37">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="12"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA54526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="510" mass="55415" checksum="A036C4143DFEDB9E" modified="2011-12-14" version="1">MALPPKVYQWLIGVFASLGSATYGYDLGIIAQVISAPSFVKRVGDNPAEIGGIVSIFTGGAFFGALAAAPTADRLGRKLCIMMGATIFIAGGLLQALAQSTAYMMAGRGIGGVGIGAMIMIIPVYQAELTHPSIRGTVTALQQFMLGVGALFAGWFSYGMTVGVSDDDENQWRISLGLQVVPAGVLALLIMLFPESPRWLIDHGRADEGLQTLARLHAHGDVDDAWVRAEYSQIRESIDAEHEAEAKSYAELFRDRSCLRRLWLAASIQASVQMTGVSSIQYYSVAIFAKMGISGSDTLKYQGISGVWALVAQALCMAFVDRLGRRWPLILGNAFNCISFIVTTALLASFPPGESGGNMSASWAFIVMTWLYNFSFSATCGPLSWIIPAEIFDMKTRAKGVSIATAVSLAFNAMIGQCSSLALDDETGIGWRWYILFIVCNATNAIYFWAVLPETARRPLEEMRYLFTEAPFFIPTMDPSRAYSNDLADRLEQAERKQDAAVEGRDETHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MZN4</accession>
    <name>G4MZN4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001232">
        <property type="protein sequence ID" value="EHA55398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003715205.1">
        <property type="nucleotide sequence ID" value="XM_003715157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MZN4"/>
    <dbReference type="SMR" id="G4MZN4"/>
    <dbReference type="GeneID" id="2683037"/>
    <dbReference type="KEGG" id="mgr:MGG_07023"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07023"/>
    <dbReference type="eggNOG" id="ENOG502SX98">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_882999_0_0_1"/>
    <dbReference type="InParanoid" id="G4MZN4"/>
    <dbReference type="OMA" id="HKEHIRM"/>
    <dbReference type="OrthoDB" id="5367448at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA55398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="315" mass="35910" checksum="AB10408489F8A0A9" modified="2011-12-14" version="1">MQIPNTVRVGLGAHVINRTVYLRVQPMPETLAERRAVLRMLQRSGEVQVFKKLRREDSFISIFRSSKDAIELVKRAPIRYELVVENTGVNLMDSRDITPTVAPIETMAHGTSDTETPAAQSQQYAELETDEPLPEQLPLTPEQQQEDGDSSAPSSTFSTVRQRSFMLSAFITNRHAHYTHIRRSRLYGPWEREQHAAQTFMSRALRNIVPSDHDSQPFADWITSDQLNEARIEEHDEQQRSGLATTYVEVRKAKREHKALLQKNMGKIGQKPVLADRVSTVQSDCRIERWGLICIFELAAPHVVIYAARLARATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4N0R7</accession>
    <name>G4N0R7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711307.1">
        <property type="nucleotide sequence ID" value="XM_003711259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N0R7"/>
    <dbReference type="STRING" id="242507.G4N0R7"/>
    <dbReference type="GeneID" id="2683341"/>
    <dbReference type="KEGG" id="mgr:MGG_07421"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07421"/>
    <dbReference type="eggNOG" id="ENOG502TGK2">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816560_0_0_1"/>
    <dbReference type="InParanoid" id="G4N0R7"/>
    <dbReference type="OrthoDB" id="3766406at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="340" mass="39676" checksum="09C4D687B1CFB0BC" modified="2011-12-14" version="1">METLQEPKLPAPTSEPPTTTFLKLPPEICNNIVAKLSPSSQICLSLTCKELYKVYFIGKKYLNGALNVTHNVLHLLERDLPGYYFCSSCIKLHRWKLRRDGTVRFIDQCKQGPERTVFNLPSRMNIRYRLDWRIVRLAHLHQMYGQEHGVPLSYLEKSSRTKLSLGNRYVEKCRRALLHEHWEAKFVKGDLLLRTTYTLTSIDRADEPWKEIMDFLSNEVDGDLYLKDINLICSEFALMGPFELASFDFEDPAAEGPVYFSCRCEGYEANRKHERLRCWTFYEASRMRDADTGGWKYVLVAFRTLSSKRKSDRHSDVALCGWDDLEFKPGGINLWEDDHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4N139</accession>
    <name>G4N139_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713022.1">
        <property type="nucleotide sequence ID" value="XM_003712974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N139"/>
    <dbReference type="GeneID" id="2683731"/>
    <dbReference type="KEGG" id="mgr:MGG_07804"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07804"/>
    <dbReference type="HOGENOM" id="CLU_1740910_0_0_1"/>
    <dbReference type="InParanoid" id="G4N139"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466440" evidence="1">
        <location>
            <begin position="21"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="150" mass="15658" checksum="DDEAF63503872B62" modified="2011-12-14" version="1">MHFTTLLGTTIALLAGQCAAASPSTPASYSAEAAAAAALGPLTRIDKPFTQCRITYTAPNKKPVVNKLGHGGTAKLSVDGVTYTAVADAKCKLVVVGSPWPAGHFTVGQVVKGKVGVPPRMEIWVDEEDIVPKMSRLGLGRRPGRARHGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2D7</accession>
    <name>G4N2D7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713149.1">
        <property type="nucleotide sequence ID" value="XM_003713101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2D7"/>
    <dbReference type="GeneID" id="12986064"/>
    <dbReference type="KEGG" id="mgr:MGG_15263"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15263"/>
    <dbReference type="HOGENOM" id="CLU_836966_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2D7"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA53342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="332" mass="36242" checksum="4386183851A6B6DE" modified="2011-12-14" version="1">MQLSAEVCKSLDLLPPDPNEPKITLRFDGTPAAVTSSGVEQGYMIPLTSKEAGLPYLQYIKAGISGTGPLWTLIGSGSTIDTLPPSVVPLLGLDLKTAKRPWRIRMADDAIAMTNKFALVNVDTGPLSFPLRMWVLGGPSSHCILLGQNWIRRTHTEQSWKDLTLILSDRDGRECQLALTDSPFDAAPAIFRRGGGPSPTRTKIILKGKETTVIPKGTRIKIAALPSFDRTSCDAERPEQGVTVDFASNIYEDTTEMTPKHGDSVEGGKREFTRDASSLPPGTETLPREDWQPTVPLLPLWPDPLADAYDEIAKDYIAEEKRAPSPEEIPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2H2</accession>
    <name>G4N2H2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_16969</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003713184.1">
        <property type="nucleotide sequence ID" value="XM_003713136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2H2"/>
    <dbReference type="SMR" id="G4N2H2"/>
    <dbReference type="STRING" id="242507.G4N2H2"/>
    <dbReference type="GeneID" id="12986112"/>
    <dbReference type="KEGG" id="mgr:MGG_16969"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16969"/>
    <dbReference type="eggNOG" id="KOG0024">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_11_5_1"/>
    <dbReference type="InParanoid" id="G4N2H2"/>
    <dbReference type="OMA" id="INHPARW"/>
    <dbReference type="OrthoDB" id="5363962at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF25">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="9">
        <location>
            <begin position="11"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA53377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="376" mass="39396" checksum="1C26186D1D6A5E3F" modified="2011-12-14" version="1">MATIKASVLYGPKDLRVEERTIPAPAAGEVQVSIRATGICGSDMHYYVHGANGDFKVREPLSLGHESAGVVEAVGPDVTDLKVGDRVAVEVGIACDDCALCKSGRYNLCKGMKFRSSAKIFPHFQGTLQDRINHPARLTYKLPDSASLAEGALLEPLGVAIHGVKRAGEQKGKTALVLGAGAVGLLTAAVLRVEGIESIAIADIVPERVQFAVAHGFADKAVVVPSKRLPPTASADEKLALARETAALLTREGNGGDEYDTTFECTGVESCVQAAIYATGPGGRVMMIGMGTPVQTLPLGAAALREVDLLGVFRYANTYPRGIELLAGRESNGMPDIGLLATQNVKGLDRAEDAFAIAAKPVDADGKLVLKVIIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2I4</accession>
    <name>G4N2I4_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endoprotease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGG_07584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711500.1">
        <property type="nucleotide sequence ID" value="XM_003711452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2I4"/>
    <dbReference type="SMR" id="G4N2I4"/>
    <dbReference type="MEROPS" id="S28.004"/>
    <dbReference type="GeneID" id="2683504"/>
    <dbReference type="KEGG" id="mgr:MGG_07584"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07584"/>
    <dbReference type="eggNOG" id="KOG2182">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023630_1_0_1"/>
    <dbReference type="InParanoid" id="G4N2I4"/>
    <dbReference type="OMA" id="FQLEHRC"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF23">
        <property type="entry name" value="SERINE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465679" description="Endoprotease" evidence="6">
        <location>
            <begin position="20"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA51693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="59819" checksum="7D823CD634F03238" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4N2L5</accession>
    <name>G4N2L5_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_07610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711531.1">
        <property type="nucleotide sequence ID" value="XM_003711483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N2L5"/>
    <dbReference type="SMR" id="G4N2L5"/>
    <dbReference type="GeneID" id="2683530"/>
    <dbReference type="KEGG" id="mgr:MGG_07610"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_07610"/>
    <dbReference type="eggNOG" id="ENOG502TGZY">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_754543_0_0_1"/>
    <dbReference type="InParanoid" id="G4N2L5"/>
    <dbReference type="OMA" id="GRQHESP"/>
    <dbReference type="OrthoDB" id="5203335at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="327" mass="35633" checksum="32C6143EF2229400" modified="2011-12-14" version="1">MLPMIRRLFRTSANDDDAKNNVAITSDAQRDRRAIHESIFKSGLLPPGVPPPKQERRRIDGYGQASENIITNVFVPILAAPGVGVRSFVNKSRYGHMDWGILSAEFAVGPPEYLCDGNVYSIGLAKLPLPHLLKSGFAVDSQHMGVVLAFALDDASSLDEAKELYRRLTQSFKLKSPGKSPLPFPAMLLGMKSDLDSAESLGGYSSDRVSTHLKSTNAHPETQEASPEADSLFPDTDQGPKALAKEFAKQNGLIYEECSAKTGYGMLTATAALVQEIEAMAKADPNPEDTLEAMRDVWIPTVSKIMDHREAKNLALPDRAVLSPRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4N363</accession>
    <name>G4N363_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptide transporter PTR2-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_04934</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712426.1">
        <property type="nucleotide sequence ID" value="XM_003712378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N363"/>
    <dbReference type="SMR" id="G4N363"/>
    <dbReference type="FunCoup" id="G4N363">
        <property type="interactions" value="1101"/>
    </dbReference>
    <dbReference type="GeneID" id="2675557"/>
    <dbReference type="KEGG" id="mgr:MGG_04934"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04934"/>
    <dbReference type="eggNOG" id="KOG1237">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004790_4_1_1"/>
    <dbReference type="InParanoid" id="G4N363"/>
    <dbReference type="OMA" id="FKCCISP"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000085">
        <property type="entry name" value="MFS peptide transporter Ptr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="595"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="639" mass="69701" checksum="0FEA3EEDAD44A428" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3H6</accession>
    <name>G4N3H6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712458.1">
        <property type="nucleotide sequence ID" value="XM_003712410.1"/>
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    <dbReference type="AlphaFoldDB" id="G4N3H6"/>
    <dbReference type="SMR" id="G4N3H6"/>
    <dbReference type="STRING" id="242507.G4N3H6"/>
    <dbReference type="GeneID" id="2675292"/>
    <dbReference type="KEGG" id="mgr:MGG_04962"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04962"/>
    <dbReference type="eggNOG" id="ENOG502RRJ9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017006_2_0_1"/>
    <dbReference type="InParanoid" id="G4N3H6"/>
    <dbReference type="OMA" id="LICCAVP"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06197">
        <property type="entry name" value="FNR_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
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    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815:SF2">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="353"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA52651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="638" mass="67375" checksum="0B2BC7963C7612AC" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>G4N3Z9</accession>
    <name>G4N3Z9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_05902</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA51921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711728.1">
        <property type="nucleotide sequence ID" value="XM_003711680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N3Z9"/>
    <dbReference type="SMR" id="G4N3Z9"/>
    <dbReference type="GeneID" id="2684073"/>
    <dbReference type="KEGG" id="mgr:MGG_05902"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05902"/>
    <dbReference type="eggNOG" id="KOG3178">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005533_5_2_1"/>
    <dbReference type="InParanoid" id="G4N3Z9"/>
    <dbReference type="OMA" id="VYDFSWV"/>
    <dbReference type="OrthoDB" id="1535081at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712:SF16">
        <property type="entry name" value="O-METHYLTRANSFERASE ELCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43712">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="241"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005739-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA51921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="404" mass="44428" checksum="BA25A208A0C2A7B9" modified="2011-12-14" version="1">MADLESLSQSADALDELAAKLSARAGELRAAVEARDEAAARTRRYEALDAAQDVVSLLKNPSEQWADTLQNVALTGVVRQFQQWKVFDAIPAAPGSSISYEELAGRTGVQLQLLRMVKQEGVDRISHTPRSLNYLEGTHGADFHNTMYSLAVKAFAMLVEYFDKYGPREPEEQNHIPVTFAMGTPELTFWGHLERHPELIAPFMHSSAPSAARMPVTGVYDFGWVAEEAKKDPGGDRVLFNDVGGGTGHCIVAIQAENPAIPMERFMLQDQPHIIDQLKRDATESLRGVKMASLDFNKEAPEKGALIYYLRRIVHDYSDKLAVNILRNTVAAMAPDSRILIAEDVATNPPHPLTAMMDMLMLAVGGKERTLEDFEAVIKEAGLRITSVARSADSPMAVIECVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>G4N4H0</accession>
    <name>G4N4H0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2293 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_05118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712645.1">
        <property type="nucleotide sequence ID" value="XM_003712597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N4H0"/>
    <dbReference type="GeneID" id="2675574"/>
    <dbReference type="KEGG" id="mgr:MGG_05118"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05118"/>
    <dbReference type="eggNOG" id="ENOG502SQI9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060995_0_0_1"/>
    <dbReference type="InParanoid" id="G4N4H0"/>
    <dbReference type="OMA" id="NCIWISS"/>
    <dbReference type="OrthoDB" id="5381833at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018744">
        <property type="entry name" value="DUF2293"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38113:SF2">
        <property type="entry name" value="DUF2293 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10056">
        <property type="entry name" value="DUF2293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2293" evidence="2">
        <location>
            <begin position="106"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA52838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="356" mass="39061" checksum="873659DA78CC4288" modified="2011-12-14" version="1">MPASKTNAANEPMVTASTPMPPGYRFVSKGNVYITKNCRKKTQAAGKTVYVVVESLKTKRVKTLGIRVPTDIYSEVAESERQTRTARATNVQKRDDAGLRAFELELRRLFPQAPADAAETVARHALVKRSRRVGRAGTMDMDKKVRLAVTAHIRHRHTDYDAMLARGVPREEARTKVWARIVEVADGWAGRPGSLKSHAAAARKEKKLARRRGDGRGSGRSGSSPAPGGGGGSKNVARKTRTAEKMNKTNNGKPLPVAKPLPDHVGKNTKLKLALRPIGVARRKPLPQVKRHNNAKQPADRPGGTDGDPFVISDDDFPHPDDDFDGASEEADDDDDFFTESDIYDSEDSDYYDEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5C5</accession>
    <name>G4N5C5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Pisatin demethylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_05235</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA52982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712789.1">
        <property type="nucleotide sequence ID" value="XM_003712741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5C5"/>
    <dbReference type="SMR" id="G4N5C5"/>
    <dbReference type="GeneID" id="2675708"/>
    <dbReference type="KEGG" id="mgr:MGG_05235"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05235"/>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_14_0_1"/>
    <dbReference type="InParanoid" id="G4N5C5"/>
    <dbReference type="OMA" id="WLHYFAF"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0000317"/>
        <property type="project" value="PAMGO_MGG"/>
    </dbReference>
    <dbReference type="CDD" id="cd11060">
        <property type="entry name" value="CYP57A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000050">
        <property type="entry name" value="Cytochrome P450 monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF232">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA52982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="58740" checksum="D820D1BADCBB0E5A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5F0</accession>
    <name>G4N5F0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Checkpoint forkhead associated with RING domains-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_05257</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DMA1 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CM001233">
        <property type="protein sequence ID" value="EHA53007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003712814.1">
        <property type="nucleotide sequence ID" value="XM_003712766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5F0"/>
    <dbReference type="SMR" id="G4N5F0"/>
    <dbReference type="FunCoup" id="G4N5F0">
        <property type="interactions" value="125"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5F0"/>
    <dbReference type="GeneID" id="2675329"/>
    <dbReference type="KEGG" id="mgr:MGG_05257"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05257"/>
    <dbReference type="eggNOG" id="KOG3872">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017542_0_1_1"/>
    <dbReference type="InParanoid" id="G4N5F0"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031578">
        <property type="term" value="P:mitotic spindle orientation checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051865">
        <property type="term" value="P:protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097271">
        <property type="term" value="P:protein localization to bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090337">
        <property type="term" value="P:regulation of formin-nucleated actin cable assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000921">
        <property type="term" value="P:septin ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000426">
        <property type="entry name" value="DMA1p Ubiquitin-protein ligase (E3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000030">
        <property type="entry name" value="FHA domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067:SF7">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE DMA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17123">
        <property type="entry name" value="zf-RING_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FHA" evidence="15">
        <location>
            <begin position="347"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="488"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="86"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="540"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="540"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="586"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00080465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA53007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="737" mass="77543" checksum="54B73B9ED63B05B0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="73" xmlns="https://uniprot.org/uniprot">
    <accession>G4N5Z2</accession>
    <name>G4N5Z2_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Pre-mRNA-processing factor 19</fullName>
            <ecNumber evidence="16">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">MGG_03116</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22 23">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the WD repeat PRP19 family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="16"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716887.1">
        <property type="nucleotide sequence ID" value="XM_003716839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N5Z2"/>
    <dbReference type="SMR" id="G4N5Z2"/>
    <dbReference type="FunCoup" id="G4N5Z2">
        <property type="interactions" value="390"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N5Z2"/>
    <dbReference type="GeneID" id="2676899"/>
    <dbReference type="KEGG" id="mgr:MGG_03116"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03116"/>
    <dbReference type="eggNOG" id="KOG0289">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023894_0_1_1"/>
    <dbReference type="InParanoid" id="G4N5Z2"/>
    <dbReference type="OMA" id="SLDQHWA"/>
    <dbReference type="OrthoDB" id="687049at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070534">
        <property type="term" value="P:protein K63-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16656">
        <property type="entry name" value="RING-Ubox_PRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000027">
        <property type="entry name" value="Pre-mRNA-processing factor 19, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038959">
        <property type="entry name" value="Prp19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013915">
        <property type="entry name" value="Prp19_cc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055340">
        <property type="entry name" value="RING-Ubox_PRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08606">
        <property type="entry name" value="Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 16" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12 16" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="14 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7 16" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 16" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4 15" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="U-box" evidence="19">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="276"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="EHA50568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="494" mass="51769" checksum="233B9BEAC9AAB31E" modified="2011-12-14" version="1">MLCSISGEAPQEPVVSTKSGNVYEKRLIEKYIDEHGKEPGSDTDLDKEDLLPIQTSRVVRPRPAALTSIPALLSTFQNEWDSLALETYNLQQQLQRTREELANALYQHDAAIRVIARLTKERNEARDALAKVTVSAPAPAAANAGDSAMAIDSELPQDVAEHVDETAQMLSKSRKKRPTPPTWASPEDISSLEKVASDSLHPLTQATSLGVDGGYAAVGGFSGDLAIYSLEAAKLERTLNVGEPVTAVLWSGTKVILGTTKGAVKVYDSGSEVASFSEHAGGVTGLAIHPGSDIVASVGADRGVVLYQLSTLKKVFQTRTDASLTMCAFHPDGALVAAGTTSGDIKLFHTKTLEEAASFPLGAPVQAVAFSENGYWFAAVAKAQTAVTIMDLRKSGDAAKVKTLDVGTGVLAALAWDYTGRFLAAAGASGVSVQGYNKSSKAWTSLLQKGDAAGAVALAWGPDAKKLVAIKPDGVLEMLGVPSAAEEEAPAAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6S4</accession>
    <name>G4N6S4_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_15286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003716162.1"/>
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    <dbReference type="InParanoid" id="G4N6S4"/>
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            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
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            <begin position="67"/>
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            <begin position="1"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA49891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="91" mass="10313" checksum="346F39ED9FAFEBFF" modified="2011-12-14" version="1">MEDWAAKPEKERDNKDHLRRSNWSTTVVSAEVCKGQFSNLARHGQSTTARLWMDDGYVRASRADLYPSEPTVFPDRQADGCSPTKVESPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6U6</accession>
    <name>G4N6U6_PYRO7</name>
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            <fullName evidence="6">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_03656</name>
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    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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            <taxon>Pyriculariaceae</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
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                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716232.1">
        <property type="nucleotide sequence ID" value="XM_003716184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6U6"/>
    <dbReference type="SMR" id="G4N6U6"/>
    <dbReference type="GeneID" id="2676599"/>
    <dbReference type="KEGG" id="mgr:MGG_03656"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03656"/>
    <dbReference type="eggNOG" id="ENOG502S4E9">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011385_0_0_1"/>
    <dbReference type="InParanoid" id="G4N6U6"/>
    <dbReference type="OMA" id="FVCLRCE"/>
    <dbReference type="OrthoDB" id="5392646at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048401">
        <property type="entry name" value="SLS1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032741">
        <property type="entry name" value="Sls1_KH-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048748">
        <property type="entry name" value="SLS1_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048400">
        <property type="entry name" value="SLS1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14611">
        <property type="entry name" value="KH_SLS1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20777">
        <property type="entry name" value="KH_SLS1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20778">
        <property type="entry name" value="SLS1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20776">
        <property type="entry name" value="SLS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLS1 N-terminal" evidence="3">
        <location>
            <begin position="198"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 first KH" evidence="2">
        <location>
            <begin position="321"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 second KH" evidence="4">
        <location>
            <begin position="396"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="SLS1 C-terminal" evidence="5">
        <location>
            <begin position="499"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA49913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="872" mass="96820" checksum="D5184AFB5E9D834A" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6W5</accession>
    <name>G4N6W5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">F-actin-capping protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_12818</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the F-actin-capping protein alpha subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717048.1">
        <property type="nucleotide sequence ID" value="XM_003717000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6W5"/>
    <dbReference type="SMR" id="G4N6W5"/>
    <dbReference type="FunCoup" id="G4N6W5">
        <property type="interactions" value="794"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N6W5"/>
    <dbReference type="GeneID" id="5050190"/>
    <dbReference type="KEGG" id="mgr:MGG_12818"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12818"/>
    <dbReference type="eggNOG" id="KOG0836">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045161_3_1_1"/>
    <dbReference type="InParanoid" id="G4N6W5"/>
    <dbReference type="OMA" id="VACIEDH"/>
    <dbReference type="OrthoDB" id="340550at2759"/>
    <dbReference type="PHI-base" id="PHI:7187"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.60">
        <property type="entry name" value="F-actin capping protein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002189">
        <property type="entry name" value="CapZ_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042489">
        <property type="entry name" value="CapZ_alpha_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017865">
        <property type="entry name" value="F-actin_cap_asu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01267">
        <property type="entry name" value="F-actin_cap_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00191">
        <property type="entry name" value="FACTINCAPA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00748">
        <property type="entry name" value="F_ACTIN_CAPPING_A_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00749">
        <property type="entry name" value="F_ACTIN_CAPPING_A_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0117">Actin capping</keyword>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA50729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="273" mass="29810" checksum="CDB921A4D3147BF9" modified="2011-12-14" version="1">MTKSTEGRCDFLVASRAVSYQDTFAFGVAPHSVAYSDNADAPFFHNSYPRLAIAPVKTTSQTSSLLRSRRIDIKSISSGDAKVVSKLAPAFERYNEEQFTTVKLPGGSQKVIVSAHNSLGDGRYYDVESSSSFAFDHTTQKASAVQSYALESAHSDLVNGRWRSLYTLDPASGAIDGSIKVDVHYYEDGNVRLLTDKATTATVPSATGSAIVKEIGSSEKKYQEELNRGFTDLSEGAFKGLRRQLPVTRQKIEWDKVASYRLGQDIGGGRRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4N6W7</accession>
    <name>G4N6W7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIE subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_06509</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TFIIE beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003717050.1">
        <property type="nucleotide sequence ID" value="XM_003717002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N6W7"/>
    <dbReference type="SMR" id="G4N6W7"/>
    <dbReference type="FunCoup" id="G4N6W7">
        <property type="interactions" value="480"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4N6W7"/>
    <dbReference type="GeneID" id="2684664"/>
    <dbReference type="KEGG" id="mgr:MGG_06509"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06509"/>
    <dbReference type="eggNOG" id="KOG3095">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056580_0_1_1"/>
    <dbReference type="InParanoid" id="G4N6W7"/>
    <dbReference type="OMA" id="RTKKDNH"/>
    <dbReference type="OrthoDB" id="5323195at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001097">
        <property type="term" value="F:TFIIH-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054600">
        <property type="entry name" value="TFA2_E-tether"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040501">
        <property type="entry name" value="TFA2_Winged_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016656">
        <property type="entry name" value="TFIIE-bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003166">
        <property type="entry name" value="TFIIE_bsu_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22254">
        <property type="entry name" value="TFA2_E-tether"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18121">
        <property type="entry name" value="TFA2_Winged_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02186">
        <property type="entry name" value="TFIIE_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016398">
        <property type="entry name" value="TFIIE-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51351">
        <property type="entry name" value="TFIIE_BETA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIE beta" evidence="9">
        <location>
            <begin position="72"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA50731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="310" mass="34133" checksum="836BB913E7E0848A" modified="2011-12-14" version="1">MSSFLERQQKAMAASLAGAASKLSGASKPNSLKRPPPSPSPSVTSTTSAAPGNDGSGSTPKKIKRETTATIFSQPAQTGYGTELGSNIIYIVDNLKEHGKPKSLDDVLGHVNLHRRDDNFKRAVVETLKAHTKVNFIRDPKAEAADPENAWKTGKYEHLPIIPGVKDETSLLRYLSERKTAQGVSVKDLKDGWPSCDETITKLEKAHKLLVVRTKKDGVARTVWIDDPSLHHDVDAEFKLMWHRVEVPPLEDIVRKLAAAGQKPTSDDPQLKVHAVAKDTKKNKKRAVNIKKMTNVHMAGLLKNFDHIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4N732</accession>
    <name>G4N732_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAR-17a/AIG1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA49945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716264.1">
        <property type="nucleotide sequence ID" value="XM_003716216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N732"/>
    <dbReference type="STRING" id="242507.G4N732"/>
    <dbReference type="GeneID" id="2676770"/>
    <dbReference type="KEGG" id="mgr:MGG_03627"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03627"/>
    <dbReference type="eggNOG" id="ENOG502RZDB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062880_0_0_1"/>
    <dbReference type="InParanoid" id="G4N732"/>
    <dbReference type="OMA" id="QHAMNSG"/>
    <dbReference type="OrthoDB" id="419711at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF1">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="30723" checksum="6514617B2CCF9A8D" modified="2011-12-14" version="1">MGNPFAFGHDEFDSSNRFVTSWFLPPWVLFACRLLFGLYALTTQFVSIGTQVALGQSADATAEFSYFTVLTYWGIAFYLLVSAVHTATYAATGRPLLARFPRSLQALHSLYYTTVSVYPFIVTIVYWGVLYVGPWFNTTFSAWSNVSRHAMNSGFALFEILVARTDLPPWIHLFWLIIILCLYLALAYVTHATKGFYVYPFLDPAGGAGKLAAYICGIAVGCIVIFLLVLGLIWLRKWVTERKLGMRGKLSSRDRPASSTISDPETAQHGKYDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>G4N892</accession>
    <name>G4N892_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_15278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716458.1">
        <property type="nucleotide sequence ID" value="XM_003716410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4N892"/>
    <dbReference type="GeneID" id="12984458"/>
    <dbReference type="KEGG" id="mgr:MGG_15278"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_15278"/>
    <dbReference type="eggNOG" id="ENOG502R1AB">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_622668_0_0_1"/>
    <dbReference type="InParanoid" id="G4N892"/>
    <dbReference type="OMA" id="FAYEMEV"/>
    <dbReference type="OrthoDB" id="4757858at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA50139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="49349" checksum="846CBE4B24845D27" modified="2011-12-14" version="1">MTSLLNLPVTVLMDTFELLCPHDPSSRVALANLCCTNKFLSAIATPILYHLAYYPDINYPEDQITAFYRTMLVERPDLCQHVRSIHLLEKDLDSLPSELVEAIKERFGIVTFTLPEDASLVPLDSGYSSSLSGHRMSLPMLLTRGCIGLQELCLVVDFMDDIIGCIPLKILPRLKTLIITMDESENQLDTPRLQTISLASPSLGVLTISGLTFFLPSKNWANLRELTLISSCLDIHVVKLLLQECPVLESFAYEMEVYDERPLDSPHTYPCDLVRAISEHTSKTLRSLNLNLRHFWSGWYFDEPAEAMGNFRSLKSLEHLEVGLESLLGNTSMEDDQDKVLCLFSWTLPARIHSVTIEASREVDSRLLGLTLDYLTKVCSEEFPELETIVVRGTYSGFKLAGVSELISSFGESGVSLELRHEPALVEQSSGDQTQVLEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>G4N8Y6</accession>
    <name>G4N8Y6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_03353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
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                <person name="Nicol R."/>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
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                <person name="Shea T."/>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
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                <person name="Soanes D.M."/>
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        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
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                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
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                <person name="Pearson M."/>
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                <person name="Saif S."/>
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                <person name="Shenoy N."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain>70-15</strain>
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    </evidence>
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<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAB1</accession>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716775.1">
        <property type="nucleotide sequence ID" value="XM_003716727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAB1"/>
    <dbReference type="STRING" id="242507.G4NAB1"/>
    <dbReference type="GeneID" id="2676751"/>
    <dbReference type="KEGG" id="mgr:MGG_03207"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03207"/>
    <dbReference type="eggNOG" id="ENOG502QUU6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015630_1_1_1"/>
    <dbReference type="InParanoid" id="G4NAB1"/>
    <dbReference type="OMA" id="HHRGAKN"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF13">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="149"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EHA50456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="611" mass="68500" checksum="DE80F5E0339430B0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="61" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAB5</accession>
    <name>G4NAB5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Replication factor C subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_03204</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the activator 1 large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003716731.1"/>
    </dbReference>
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    <dbReference type="SMR" id="G4NAB5"/>
    <dbReference type="FunCoup" id="G4NAB5">
        <property type="interactions" value="1031"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAB5"/>
    <dbReference type="GeneID" id="2676508"/>
    <dbReference type="KEGG" id="mgr:MGG_03204"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03204"/>
    <dbReference type="eggNOG" id="KOG1968">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003574_1_1_1"/>
    <dbReference type="InParanoid" id="G4NAB5"/>
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    <dbReference type="Proteomes" id="UP000009058">
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    <dbReference type="GO" id="GO:0005663">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902983">
        <property type="term" value="P:DNA strand elongation involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17752">
        <property type="entry name" value="BRCT_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000021">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000005">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000001">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000395">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
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        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013725">
        <property type="entry name" value="DNA_replication_fac_RFC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="InterPro" id="IPR012178">
        <property type="entry name" value="RFC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF6">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08519">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="12">
        <location>
            <begin position="339"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="424"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1001"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="430"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1029"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1055"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1070"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA50460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="1084" mass="117815" checksum="43970EA401A46C7E" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAD9</accession>
    <name>G4NAD9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,4-alpha-glucan-branching enzyme</fullName>
            <ecNumber evidence="4">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glycogen-branching enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_03186</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Glycogen-branching enzyme participates in the glycogen biosynthetic process along with glycogenin and glycogen synthase. Generates alpha-1,6-glucosidic branches from alpha-1,4-linked glucose chains, to increase solubility of the glycogen polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CM001234">
        <property type="protein sequence ID" value="EHA50484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003716803.1">
        <property type="nucleotide sequence ID" value="XM_003716755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAD9"/>
    <dbReference type="SMR" id="G4NAD9"/>
    <dbReference type="FunCoup" id="G4NAD9">
        <property type="interactions" value="426"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NAD9"/>
    <dbReference type="CAZy" id="CBM48">
        <property type="family name" value="Carbohydrate-Binding Module Family 48"/>
    </dbReference>
    <dbReference type="CAZy" id="GH13">
        <property type="family name" value="Glycoside Hydrolase Family 13"/>
    </dbReference>
    <dbReference type="GeneID" id="2676993"/>
    <dbReference type="KEGG" id="mgr:MGG_03186"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03186"/>
    <dbReference type="eggNOG" id="KOG0470">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011131_2_2_1"/>
    <dbReference type="InParanoid" id="G4NAD9"/>
    <dbReference type="OMA" id="YEMHLGS"/>
    <dbReference type="OrthoDB" id="196493at2759"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11321">
        <property type="entry name" value="AmyAc_bac_euk_BE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02854">
        <property type="entry name" value="E_set_GBE_euk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000001">
        <property type="entry name" value="1,4-alpha-glucan branching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000250">
        <property type="entry name" value="1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000003">
        <property type="entry name" value="1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651:SF3">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="12">
        <location>
            <begin position="213"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA50484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="691" mass="79078" checksum="25302E956941C51F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4NAJ4</accession>
    <name>G4NAJ4_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003717603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NAJ4"/>
    <dbReference type="GeneID" id="12986592"/>
    <dbReference type="KEGG" id="mgr:MGG_17281"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17281"/>
    <dbReference type="HOGENOM" id="CLU_2413690_0_0_1"/>
    <dbReference type="InParanoid" id="G4NAJ4"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 4"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA51332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="92" mass="9710" checksum="6D5BF2856DEA5A51" modified="2011-12-14" version="1">MYRRTVLGLASWWSGPLGNNNAEWFPCAVMSEASITTGRKEPGQASPTPYHVRPSQPSGGANEISTATLANKTVANLRSSGLVEIAAPQPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NB87</accession>
    <name>G4NB87_PYRO7</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718433.1">
        <property type="nucleotide sequence ID" value="XM_003718385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NB87"/>
    <dbReference type="GeneID" id="12984089"/>
    <dbReference type="KEGG" id="mgr:MGG_17415"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17415"/>
    <dbReference type="HOGENOM" id="CLU_2347107_0_0_1"/>
    <dbReference type="InParanoid" id="G4NB87"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="16"/>
            <end position="44"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="58"/>
            <end position="97"/>
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    </feature>
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            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="58"/>
            <end position="70"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="97" mass="10888" checksum="7734A07B014040FE" modified="2011-12-14" version="1">MLSYYAIDRLPPAHYRHALPWPADKPDPDRRAGEQSKPVTPCNFFGPFRALRHELLTKGREPQDHLRSKQEPGSPGLRDRSPSVGSSVLSFSPALDI</sequence>
</entry>
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    <accession>G4NBM0</accession>
    <name>G4NBM0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ORF">MGG_10772</name>
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        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <lineage>
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            <taxon>Sordariomycetes</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_003717661.1"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_10772"/>
    <dbReference type="eggNOG" id="ENOG502SRNX">
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    <dbReference type="InParanoid" id="G4NBM0"/>
    <dbReference type="OMA" id="TQTLWLV"/>
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        <property type="entry name" value="Burnettramic_acid_biosynth"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38887:SF1">
        <property type="entry name" value="RAS MODIFICATION PROTEIN ERF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        </location>
    </feature>
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        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA48125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="302" mass="31380" checksum="94C332AA9C6A6D9C" modified="2011-12-14" version="1">MSGNKQAEATADALPSYDQTTAARSGGASTPQKQQPTIESPFNFPTDAPPSYAQAKPFEQPVALPQERPDAKAPFLSAYPPSLEMYGITAGTWHAFVHTINGFLTASVGDKAVSHAADMARHVGNVPKQFGQATASHARTVRHDIADKARAGNYFGAGFGVIGGAISLPVGTALRAVGAVVSLPFAAINAAASKPKTPRERATAYVGAANKDWFHPRQLHAGILDSSEVAHLVHATPDAIVSGANEKRASGTAAQMSVLGQWLAPVVVGDDAAHVSLNLTTNTLWLVVTHGIEPVTAGATKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>G4NC34</accession>
    <name>G4NC34_PYRO7</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">MGG_17454</name>
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        <name type="synonym">Magnaporthe oryzae</name>
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        <lineage>
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            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718621.1">
        <property type="nucleotide sequence ID" value="XM_003718573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NC34"/>
    <dbReference type="GeneID" id="12984931"/>
    <dbReference type="KEGG" id="mgr:MGG_17454"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17454"/>
    <dbReference type="HOGENOM" id="CLU_2413694_0_0_1"/>
    <dbReference type="InParanoid" id="G4NC34"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="92" mass="10084" checksum="7A83FB04A13D7E5E" modified="2011-12-14" version="1">MSRCHGCTPVAKLIHVGVGQLHGLKKSATGPDQKGYISRQSNAQKDNHFIGLNVSLSVGYWARADRLEKHDREVIGETEQAKPYLMGNIVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4ND97</accession>
    <name>G4ND97_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_00278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718819.1">
        <property type="nucleotide sequence ID" value="XM_003718771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ND97"/>
    <dbReference type="GeneID" id="2674616"/>
    <dbReference type="KEGG" id="mgr:MGG_00278"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00278"/>
    <dbReference type="HOGENOM" id="CLU_2386604_0_0_1"/>
    <dbReference type="InParanoid" id="G4ND97"/>
    <dbReference type="OrthoDB" id="10392573at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA49235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="94" mass="9936" checksum="87017D46DED55559" modified="2011-12-14" version="1">MHSPTILASAANVTAMTRCDKKKFNACTAKCHENRNCIGGNLDIGCISACAATNPKMQVEGEEVRQGKVQHHGSKCYENRNGVGGNVDIGCISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDD5</accession>
    <name>G4NDD5_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="11">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_00942</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="11"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718008.1">
        <property type="nucleotide sequence ID" value="XM_003717960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDD5"/>
    <dbReference type="SMR" id="G4NDD5"/>
    <dbReference type="STRING" id="242507.G4NDD5"/>
    <dbReference type="GeneID" id="2674201"/>
    <dbReference type="KEGG" id="mgr:MGG_00942"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00942"/>
    <dbReference type="eggNOG" id="KOG0975">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031922_0_0_1"/>
    <dbReference type="InParanoid" id="G4NDD5"/>
    <dbReference type="OMA" id="ICTDHMV"/>
    <dbReference type="OrthoDB" id="1732691at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000012">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF69">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 11 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 13" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="EHA48424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="419" mass="45878" checksum="44C560EC25C55325" modified="2011-12-14" version="1">MAPPAAITPVTPGTPEPSLNKGGPDTNLTAAAIGHKMSQASEYQELDASKLIYNLTTSPRALPDYDTAAAGSETVCTDHMVTANWHAATGWSAPTIKPYGPLSLMPTASVLHYATECFEGLKAYRGYDGKLRLFRPDRNANRMLMSSVRIALPSFPPEALEKLLIALMAVDGPKWLPRERPGTLLYLRPTMIGTQAQLGVQAPNQAMLFITASYFPTMDSPAGGMRLHTSPEDMVRAWVGGFGYAKVGANYGPSLLATKEAKSRGFHQILWLYGPEGYCTEAGASNFFVLMKNKQTGRLEIVTAPLDDRVILGGITRMSVLELARSRLGDEVDVVERRYTIDEVFEAYAEGRIVESFASGTAYFVCPISLIHHRGKEVSIPMGEDGQGGKYTLKLKQWLKDIMYGNEQHEWGVVVPEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDD7</accession>
    <name>G4NDD7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tripeptidyl-peptidase II</fullName>
            <ecNumber evidence="4">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">MGG_00940</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
            <location evidence="3">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="4"/>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718010.1">
        <property type="nucleotide sequence ID" value="XM_003717962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NDD7"/>
    <dbReference type="SMR" id="G4NDD7"/>
    <dbReference type="STRING" id="242507.G4NDD7"/>
    <dbReference type="GeneID" id="2674762"/>
    <dbReference type="KEGG" id="mgr:MGG_00940"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00940"/>
    <dbReference type="eggNOG" id="ENOG502QR6D">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013783_3_0_1"/>
    <dbReference type="InParanoid" id="G4NDD7"/>
    <dbReference type="OMA" id="VTITPDC"/>
    <dbReference type="OrthoDB" id="409122at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04056">
        <property type="entry name" value="Peptidases_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11377">
        <property type="entry name" value="Pro-peptidase_S53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000015">
        <property type="entry name" value="Tripeptidyl peptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015366">
        <property type="entry name" value="S53_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030400">
        <property type="entry name" value="Sedolisin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050819">
        <property type="entry name" value="Tripeptidyl-peptidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218:SF35">
        <property type="entry name" value="PEPTIDASE S53 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14218">
        <property type="entry name" value="PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09286">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00944">
        <property type="entry name" value="Pro-kuma_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51695">
        <property type="entry name" value="SEDOLISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 15" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase S53" evidence="16">
        <location>
            <begin position="243"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15">
        <location>
            <position position="534"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="576"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="577"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="609"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="611"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="EHA48426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="639" mass="69061" checksum="6E895EB5641BC529" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NDQ8</accession>
    <name>G4NDQ8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_00886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
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                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
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                <person name="Heiman D."/>
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                <person name="Roberts A."/>
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                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Stolte C."/>
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                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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    </reference>
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                <person name="Dead R."/>
                <person name="Young S.K."/>
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                <person name="Gargeya S."/>
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                <person name="Abouelleil A."/>
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                <person name="Arachchi H.M."/>
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                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Neiman D."/>
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                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
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                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="EHA48574.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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    </evidence>
    <sequence length="113" mass="12110" checksum="FE171DD5B8A3702E" modified="2011-12-14" version="1">MAAILLGFIASSAVVALPAGIQAGPDHPDRVQRRGASSSAQRSGGDKSEDRPSLREIMKEPGWAWRIASLTPTGRELVKEAKIAQQERDEARRRAFEAGYSPDPRAGGTSVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEI7</accession>
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        <submittedName>
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                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
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            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
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                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
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                <person name="Abouelleil A."/>
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                <person name="Arachchi H.M."/>
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                <person name="Dunbar C."/>
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                <person name="Gearin G."/>
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                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
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                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
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            <begin position="1"/>
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="474" mass="52661" checksum="DE4433993595FB20" modified="2011-12-14" version="1">MARSRAKRRTHAGAKNPNQQKGPINTGNASIRDPKSMVIRIGAGEVGSSVSQLATDVRRVMEPGTASRLKERRANKLRDYLVMCGPLGVTHLLLFSRSESGNVNLRVALTPRGPTLHFRVEKYSLTKDVQKSQRRPKGQGKEFVTSPLLVMNNFSSSSADAPSKTPKHLESLTTTVFQSLFAPINPQKTSLKSIRRVLLMNREQSKEMDGSFIIDFRHYAITTKPTGISKPLKRLNAAEKLLSGKTGKKGGLPNLNKLQDIADYMIGGEDGSGYMTDGGTSGSEAETDAEVEVLEPTSRKVLNAKARAAMREAENGDEGSQAGTEQQNVEKRAVKLAELGPRMRLRLLKVEEGVCAGKVMWHEYINKSKEEIKAMEKKWEQKQREKEARKKVQKENVERKRKEKEEQKKNSKKSGENADGDDDDEDEMDVDYDSDDYEFDSEGMAGDAETLVNEKAEEDGEWEDEEEEIAAGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEQ9</accession>
    <name>G4NEQ9_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cellobiose dehydrogenase-like cytochrome domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA49482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719066.1">
        <property type="nucleotide sequence ID" value="XM_003719018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEQ9"/>
    <dbReference type="SMR" id="G4NEQ9"/>
    <dbReference type="GeneID" id="2675042"/>
    <dbReference type="KEGG" id="mgr:MGG_00074"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00074"/>
    <dbReference type="eggNOG" id="ENOG502QPZ1">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081649_1_0_1"/>
    <dbReference type="InParanoid" id="G4NEQ9"/>
    <dbReference type="OMA" id="GHMTYNP"/>
    <dbReference type="OrthoDB" id="413885at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF5">
        <property type="entry name" value="CELLOBIOSE DEHYDROGENASE CYTOCHROME DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466874" description="Cellobiose dehydrogenase-like cytochrome domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Cellobiose dehydrogenase-like cytochrome" evidence="2">
        <location>
            <begin position="25"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA49482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="221" mass="23776" checksum="7564B6ABA9377871" modified="2011-12-14" version="1">MRSFLYAVGVATLLNQALGQESVEYQDALTGFTFSRHDSGRGVSFGIAIPGNVTSGEPYDAVIQMTASKDIGWYGIAWGGSMTYNPISLAYPNGDDVTLSARMAFGYFPPVTYPDATHQVLPTGTFVNETHWQVTARCTGCTQWGDDDIGVTYLDPSEDQYLAYALSTTPVDDPADPESSFSIHSQTGHFVQNFAGGANEDFEDLVQKNLGEVDAAEGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NEX9</accession>
    <name>G4NEX9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Microfibril-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_00716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001235">
        <property type="protein sequence ID" value="EHA48705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003718289.1">
        <property type="nucleotide sequence ID" value="XM_003718241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NEX9"/>
    <dbReference type="SMR" id="G4NEX9"/>
    <dbReference type="STRING" id="242507.G4NEX9"/>
    <dbReference type="GeneID" id="2674856"/>
    <dbReference type="KEGG" id="mgr:MGG_00716"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_00716"/>
    <dbReference type="eggNOG" id="KOG1425">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022379_0_0_1"/>
    <dbReference type="InParanoid" id="G4NEX9"/>
    <dbReference type="OMA" id="FHNERAG"/>
    <dbReference type="OrthoDB" id="1111734at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033194">
        <property type="entry name" value="MFAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009730">
        <property type="entry name" value="MFAP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15327">
        <property type="entry name" value="MICROFIBRIL-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06991">
        <property type="entry name" value="MFAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Micro-fibrillar-associated protein 1 C-terminal" evidence="2">
        <location>
            <begin position="125"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA48705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="489" mass="55293" checksum="155E072E97D28F7C" modified="2011-12-14" version="1">MPPKFTANPQKPSRYRAGKPTQPESSSESDSDDEQPREKAAKKVPEPAAAARKPTGAGKIISTGSASKSVVPSVKPSTGVDAAARARAEAERKAKEDGFVTESEESGSGESGEEDSDDESGSSSSSEDEAPRRRLMMRPKFIPKSQRNAAQDASASGDKPDEEADAAARQAALDAAIEEQVRKDAAAKAAGQKHWEDDSDAEPGSDFVDDTDDIDPEAEYAAWKVRELKRLKREREAIEEREREVQEKERRMALTEEERRAEDEAKIAKQREEQANRGKMGYMQKYFHKGAFFADDAAREGLNKRDLAGVRFQDDVKNRELLPQALQMRDMTKLGKKGATRYKDLRSEDTGRWGDSGGKDRYGRGLGDRFDGDERFRPDNDRGGGYGPDGAKGANAIPLGERKEDSRRDRYQESRRDDSRDRDRKSYRTRSRSRSPRRQDRRDYDRDRHTSRSPRRDRRDYSRERRKRSTSRGGRDGDHGDKRRRIDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G4NF97</accession>
    <name>G4NF97_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="7">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_14907</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>deamido-NAD(+) + L-glutamine + ATP + H2O = L-glutamate + AMP + diphosphate + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="7"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="XP_003719646.1">
        <property type="nucleotide sequence ID" value="XM_003719598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NF97"/>
    <dbReference type="SMR" id="G4NF97"/>
    <dbReference type="FunCoup" id="G4NF97">
        <property type="interactions" value="737"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NF97"/>
    <dbReference type="GeneID" id="12986138"/>
    <dbReference type="KEGG" id="mgr:MGG_14907"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14907"/>
    <dbReference type="eggNOG" id="KOG2303">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011884_2_0_1"/>
    <dbReference type="InParanoid" id="G4NF97"/>
    <dbReference type="OMA" id="LYVVNWP"/>
    <dbReference type="OrthoDB" id="2020662at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
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        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07570">
        <property type="entry name" value="GAT_Gln-NAD-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000036">
        <property type="entry name" value="Glutamine-dependent NAD(+) synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090:SF9">
        <property type="entry name" value="GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA47279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="705" mass="78674" checksum="DD5F1491DCEEF045" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFP6</accession>
    <name>G4NFP6_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase S41 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_08761</name>
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    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719220.1">
        <property type="nucleotide sequence ID" value="XM_003719172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFP6"/>
    <dbReference type="STRING" id="242507.G4NFP6"/>
    <dbReference type="GeneID" id="2678913"/>
    <dbReference type="KEGG" id="mgr:MGG_08761"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08761"/>
    <dbReference type="eggNOG" id="ENOG502S18W">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014251_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFP6"/>
    <dbReference type="OMA" id="NEYEFGF"/>
    <dbReference type="OrthoDB" id="3534988at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056186">
        <property type="entry name" value="PDZ_CPAF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23658">
        <property type="entry name" value="PDZ_CPAF_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466906" evidence="3">
        <location>
            <begin position="24"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="876"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="domain" description="CPAF-like PDZ" evidence="5">
        <location>
            <begin position="295"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Tail specific protease" evidence="4">
        <location>
            <begin position="498"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA46853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="898" mass="95816" checksum="4F405F224B02E1B0" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>G4NFY1</accession>
    <name>G4NFY1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_17586</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719305.1">
        <property type="nucleotide sequence ID" value="XM_003719257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NFY1"/>
    <dbReference type="STRING" id="242507.G4NFY1"/>
    <dbReference type="GeneID" id="12985753"/>
    <dbReference type="KEGG" id="mgr:MGG_17586"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17586"/>
    <dbReference type="eggNOG" id="ENOG502RUEV">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1069886_0_0_1"/>
    <dbReference type="InParanoid" id="G4NFY1"/>
    <dbReference type="OrthoDB" id="5242881at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA46938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="260" mass="28830" checksum="782FE05C3A74B8ED" modified="2011-12-14" version="1">MDPLPQQKREPPPPEEINGEPEFVVDKVLASRLFGRSKILQYQVAWQGCDPDDTWYPAENFKNSATALDDFHKKYKDAAGPPKRLAIWIKAAAEDKLDEPNQEDNVAEHGELNGNQVTDPKLIRTQVHVAVVARDGVAPKMSFQSCNPLLDKERYQISPGRIPHDPVHDRIGCADFLQVDLRVEKLCESVIVKQSCHAPVPLGAELGEQRSDVVAVRLHVVLASVKDAPRLRSSLLAPGSSGVVSSAVRHGPDRRDRIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG16</accession>
    <name>G4NG16_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_01922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719340.1">
        <property type="nucleotide sequence ID" value="XM_003719292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG16"/>
    <dbReference type="SMR" id="G4NG16"/>
    <dbReference type="GeneID" id="2681137"/>
    <dbReference type="KEGG" id="mgr:MGG_01922"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01922"/>
    <dbReference type="eggNOG" id="ENOG502QU9T">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029940_1_0_1"/>
    <dbReference type="InParanoid" id="G4NG16"/>
    <dbReference type="OMA" id="GYLHEPM"/>
    <dbReference type="OrthoDB" id="3162524at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47561:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G05030)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="29"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="314" mass="35836" checksum="005BDA7336244801" modified="2011-12-14" version="1">MGKKRVLVSYGVDVDAVAGWLGSYGGEDSSNDISRGYFAGTIGTQRVLKFLAKYDIKATWFIPGHSLETFPEDMAAVRDAGHEIGLHGYSHENPTDMSMDQQREVLDRTYRMLTEFNNGKPPRGSVAPWWETSKEGAQLLLDYGIEYDHSMSHHDCQAYYLRTGDDWTKIDYKARAKDWMKPLVKGQDTGLVEIPANWYLDDLPPMMFIKAAPNSHGFVNARDVEAIWRDHFDYFYREHDEFIFPITIHPDVSGRPHAILMHERLIEHMKSHEGVEFVTMEQICDEFKSKNAPPAGAVMPAPPGEMLKKPPVWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG20</accession>
    <name>G4NG20_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">DNA replication complex GINS protein PSF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_01917</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GINS2/PSF2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719344.1">
        <property type="nucleotide sequence ID" value="XM_003719296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG20"/>
    <dbReference type="SMR" id="G4NG20"/>
    <dbReference type="FunCoup" id="G4NG20">
        <property type="interactions" value="669"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NG20"/>
    <dbReference type="GeneID" id="2681132"/>
    <dbReference type="KEGG" id="mgr:MGG_01917"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_01917"/>
    <dbReference type="eggNOG" id="KOG4071">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_078274_0_0_1"/>
    <dbReference type="InParanoid" id="G4NG20"/>
    <dbReference type="OMA" id="DSLNCMY"/>
    <dbReference type="OrthoDB" id="1938138at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11712">
        <property type="entry name" value="GINS_A_psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21694">
        <property type="entry name" value="GINS_B_Psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1020:FF:000001">
        <property type="entry name" value="DNA replication complex GINS protein PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.5.50:FF:000001">
        <property type="entry name" value="DNA replication complex GINS protein PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007257">
        <property type="entry name" value="GINS_Psf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056784">
        <property type="entry name" value="PSF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25005">
        <property type="entry name" value="PSF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028998">
        <property type="entry name" value="GINS_Psf2_subgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF2 N-terminal" evidence="11">
        <location>
            <begin position="10"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="GINS subunit" evidence="10">
        <location>
            <begin position="73"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR028998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA46977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="247" mass="26536" checksum="C45B051625456B03" modified="2011-12-14" version="1">MALPLPPGLTPSEIAFLCENELVTIVPRQRLESIPLLQGPTPTLRPPHRATLPLWLALLLKKQRRANIIAPPWMHPASLQQIIQHETHTDPVAFSPPPPPPSRADGRGGARRANIVGSTILSPPFLPSCTAESPAGYLPYHWLEMAEILLAHAPDDMPASAGEVRGLIRDLVEVRAAKMRASSADVEGFGGGVMSLRGVGGAELAENRGFVLGVVDGVRKLGASTEATRREEEEAGREDESDEDMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NG38</accession>
    <name>G4NG38_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_17597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA46991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719358.1">
        <property type="nucleotide sequence ID" value="XM_003719310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NG38"/>
    <dbReference type="GeneID" id="12985818"/>
    <dbReference type="KEGG" id="mgr:MGG_17597"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17597"/>
    <dbReference type="HOGENOM" id="CLU_203399_0_0_1"/>
    <dbReference type="InParanoid" id="G4NG38"/>
    <dbReference type="OrthoDB" id="10306254at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466195" evidence="1">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="55" mass="5650" checksum="5CB739E033CEF171" modified="2011-12-14" version="1">MLSLKAFLLLSVSCLAHLAAAGPLEHAQMESRNLICAVSGIKKGTDGTHPGDACT</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGA3</accession>
    <name>G4NGA3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719427.1">
        <property type="nucleotide sequence ID" value="XM_003719379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGA3"/>
    <dbReference type="GeneID" id="2682021"/>
    <dbReference type="KEGG" id="mgr:MGG_10409"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10409"/>
    <dbReference type="HOGENOM" id="CLU_763071_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGA3"/>
    <dbReference type="OMA" id="WEPPERC"/>
    <dbReference type="OrthoDB" id="4770059at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="363" mass="38043" checksum="985E7F1E50253AC4" modified="2011-12-14" version="1">MTTVTYDNDNVVTLPRWTTSTNLGTLTRVSFPPECLKDLARFNHPATALGPPHAYITQGCALNKCCPPGGAYTEDWAYVTSYHSPGVCPSEYKRCDFQGTHPAFKTATDEIVRFCCPSNYACPAVTGDLIKPCESIATTRQLVITVYDDVEAQKPIATTTIDGVGGGPRAAETTGVINVAYPIQVRFKQGEDAALVLGGRVLPTVGSATLLVASATPSPGGNGGGGASSTNQNPSTSAGGGGGGGSGRGIPMGLVVGVILVAAVGVAVAAIVAAMRVVRKRRREQGLPASAQQAAAMRAADVERRSQRTAQQRMAQQQQQQQQTGVEMFPPHGIPPDHRQRKLSVQHHGTATSSRVELQGNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGK1</accession>
    <name>G4NGK1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">MGG_04104</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719728.1">
        <property type="nucleotide sequence ID" value="XM_003719680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NGK1"/>
    <dbReference type="SMR" id="G4NGK1"/>
    <dbReference type="FunCoup" id="G4NGK1">
        <property type="interactions" value="699"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGK1"/>
    <dbReference type="GeneID" id="2677604"/>
    <dbReference type="KEGG" id="mgr:MGG_04104"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04104"/>
    <dbReference type="eggNOG" id="KOG3434">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105624_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGK1"/>
    <dbReference type="OMA" id="YQLRFYN"/>
    <dbReference type="OrthoDB" id="10259820at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.210:FF:000001">
        <property type="entry name" value="60S ribosomal protein L22 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF31">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL22A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EHA47361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="125" mass="14222" checksum="CE68F9554323B69F" modified="2011-12-14" version="1">MAPPQTKKTGKSSKTTKKFVINASQPVNDKIFDISAFEKFLNEKIKIDGRVGQLGDTIVISQVPDGKIEIVAHNELSGRYLKYLTKKFLKKQQLRDWLRVVSTSKGVYELKFFNVVNDADDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G4NGW7</accession>
    <name>G4NGW7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_04006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003719844.1">
        <property type="nucleotide sequence ID" value="XM_003719796.1"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4NGW7"/>
    <dbReference type="GeneID" id="2677276"/>
    <dbReference type="KEGG" id="mgr:MGG_04006"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04006"/>
    <dbReference type="eggNOG" id="ENOG502SAYM">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_262393_0_0_1"/>
    <dbReference type="InParanoid" id="G4NGW7"/>
    <dbReference type="OMA" id="WHHEDWR"/>
    <dbReference type="OrthoDB" id="9994905at2759"/>
    <dbReference type="PHI-base" id="PHI:3067"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="154"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="837"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="923"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1112"/>
        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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            <end position="137"/>
        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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        <location>
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        </location>
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            <begin position="1320"/>
            <end position="1332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA47477.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="52" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
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        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="242507.G4NGX3"/>
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    <dbReference type="VEuPathDB" id="FungiDB:MGG_12128"/>
    <dbReference type="eggNOG" id="ENOG502QTEW">
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    <dbReference type="OMA" id="YYGFLAM"/>
    <dbReference type="OrthoDB" id="5405745at2759"/>
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    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
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        <property type="term" value="P:calcium ion import across plasma membrane"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
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</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>G4NH63</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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            <taxon>Sordariomycetidae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
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                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="EHA47573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="XM_003719892.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="12987096"/>
    <dbReference type="KEGG" id="mgr:MGG_17726"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17726"/>
    <dbReference type="HOGENOM" id="CLU_1283469_0_0_1"/>
    <dbReference type="InParanoid" id="G4NH63"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="215" mass="24071" checksum="13B40043E81EF8AF" modified="2011-12-14" version="1">MVTTVLSSRPLQYIIFWAWRTSRTWPSVLFDVDKTGGGTWWWGDGFSLRTWVRFALSYEVVRRTPASYDDVAKSGDGYGVAILTATYLTEDCISINQPVMIIVLKDRARSLASRTLPPSLRMKEPVNTGRKTCVAVFPVLSFLCHPSDRSTRPGNPGFSNTHTADEIAARLCLTGVWTLPACWGPVWGLLKEPSSEKFLTSIFFFLESVRARGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHS0</accession>
    <name>G4NHS0_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_14372</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720147.1">
        <property type="nucleotide sequence ID" value="XM_003720099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHS0"/>
    <dbReference type="GeneID" id="2680327"/>
    <dbReference type="KEGG" id="mgr:MGG_14372"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_14372"/>
    <dbReference type="eggNOG" id="ENOG502SKG6">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_6_3_1"/>
    <dbReference type="InParanoid" id="G4NHS0"/>
    <dbReference type="OMA" id="IMAMSEV"/>
    <dbReference type="OrthoDB" id="5209144at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF143">
        <property type="entry name" value="EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466565" description="Rhodopsin domain-containing protein" evidence="8">
        <location>
            <begin position="30"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="9">
        <location>
            <begin position="156"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="9">
        <location>
            <begin position="268"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA47780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="519" mass="55847" checksum="297C7E3B0C39C701" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>G4NHX7</accession>
    <name>G4NHX7_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="10">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">MGG_09404</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>feruloyl-polysaccharide + H2O = ferulate + polysaccharide.</text>
            <dbReference type="EC" id="3.1.1.73"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tannase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720204.1">
        <property type="nucleotide sequence ID" value="XM_003720156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NHX7"/>
    <dbReference type="SMR" id="G4NHX7"/>
    <dbReference type="GeneID" id="2680361"/>
    <dbReference type="KEGG" id="mgr:MGG_09404"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09404"/>
    <dbReference type="eggNOG" id="ENOG502SHYE">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014819_1_0_1"/>
    <dbReference type="InParanoid" id="G4NHX7"/>
    <dbReference type="OMA" id="HCNSGPG"/>
    <dbReference type="OrthoDB" id="3039123at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030600">
        <property type="term" value="F:feruloyl esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011118">
        <property type="entry name" value="Tannase/feruloyl_esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33938:SF15">
        <property type="entry name" value="FERULOYL ESTERASE B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07519">
        <property type="entry name" value="Tannase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0858">Xylan degradation</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005132188" description="Carboxylic ester hydrolase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="520"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EHA47837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="540" mass="58740" checksum="8565962B0CC50E8F" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>G4NI82</accession>
    <name>G4NI82_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_17814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA47942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720309.1">
        <property type="nucleotide sequence ID" value="XM_003720261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NI82"/>
    <dbReference type="SMR" id="G4NI82"/>
    <dbReference type="GeneID" id="12987281"/>
    <dbReference type="KEGG" id="mgr:MGG_17814"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17814"/>
    <dbReference type="HOGENOM" id="CLU_2121573_0_0_1"/>
    <dbReference type="InParanoid" id="G4NI82"/>
    <dbReference type="OrthoDB" id="10410667at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.210.10">
        <property type="entry name" value="Heat-Labile Enterotoxin, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA47942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="114" mass="12971" checksum="6FFB39BAB9790E20" modified="2011-12-14" version="1">MLKQSGLDIPPNRGYISTTTSYDDALALAQQEKPANGQIWIYVINTKLAHDLGVEFKSVDKTFDTAHYPYKTYSENEWTVNAKIPSKAITYYRTIKSNNKMSHGVFDNFGRSGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIE0</accession>
    <name>G4NIE0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="6">N-acetyltransferase ats1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MGG_09867</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720367.1">
        <property type="nucleotide sequence ID" value="XM_003720319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIE0"/>
    <dbReference type="SMR" id="G4NIE0"/>
    <dbReference type="STRING" id="242507.G4NIE0"/>
    <dbReference type="GeneID" id="2680824"/>
    <dbReference type="KEGG" id="mgr:MGG_09867"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09867"/>
    <dbReference type="eggNOG" id="KOG3216">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_41_2_1"/>
    <dbReference type="InParanoid" id="G4NIE0"/>
    <dbReference type="OMA" id="QSEWVRY"/>
    <dbReference type="OrthoDB" id="7305308at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000064">
        <property type="entry name" value="GNAT family acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051016">
        <property type="entry name" value="Diverse_Substrate_AcTransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545">
        <property type="entry name" value="DIAMINE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545:SF29">
        <property type="entry name" value="GH14572P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="EHA48000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="184" mass="20636" checksum="E8197AFAF9666A13" modified="2011-12-14" version="1">MATIKHASREDIPAILGMIRELADYEHELHSVETTEAKLLETVALAPSDPSAPLSLPDGLPNTEPTSPAKPARCLVLSDPDGTTCGMALYFYNYSTWRARPGIYLEDLYVRPAYRKKGYGLQLLATLAREVREMQGTRLEWACLKWNEPSIKFYESIGARQQSEWVGFRVDGDNLAKLADMSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>G4NIF9</accession>
    <name>G4NIF9_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_09851</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM001236">
        <property type="protein sequence ID" value="EHA48019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720386.1">
        <property type="nucleotide sequence ID" value="XM_003720338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NIF9"/>
    <dbReference type="STRING" id="242507.G4NIF9"/>
    <dbReference type="GeneID" id="2680808"/>
    <dbReference type="KEGG" id="mgr:MGG_09851"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09851"/>
    <dbReference type="eggNOG" id="ENOG502RUAF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_816563_0_0_1"/>
    <dbReference type="InParanoid" id="G4NIF9"/>
    <dbReference type="OMA" id="KFCEAAS"/>
    <dbReference type="OrthoDB" id="5232732at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="220"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA48019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="340" mass="35719" checksum="0AB967052A2D8036" modified="2011-12-14" version="1">MPILNVITPVANSMKKELPCLSNGLCYDVGWNTLKRYSCTDKDWKSDLCPKFCEAASREAPAEIRQCSGSSDLWVCGSRSDECGMGNFTLPMGQVADGRPFSQNGVLQAGTCVADAPSSGGQQGGSGVGRPGGPPPWLTAACSATTVTAIPTATPNACVVAAVAADQVDEERKKSQEKVVAVGVGVGVGVSVPLLAALAGMVFLFTRARKEAAAAKAALADIQSQQNQRDRGSELPPRAKDPNTPSPPHILSSLPLYGMTPAMEKHHRTVHEAESLAFTNQLGTRPEEVAVVHEAPSGSPTVLSITPLSGGTSPVNLLSPDSVHTQKVLFEPGERNHWFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJ79</accession>
    <name>G4NJ79_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721038.1">
        <property type="nucleotide sequence ID" value="XM_003720990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJ79"/>
    <dbReference type="GeneID" id="2682320"/>
    <dbReference type="KEGG" id="mgr:MGG_02720"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02720"/>
    <dbReference type="HOGENOM" id="CLU_774043_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJ79"/>
    <dbReference type="OMA" id="ATPDCPI"/>
    <dbReference type="OrthoDB" id="10652973at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466607" evidence="2">
        <location>
            <begin position="19"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="358" mass="35443" checksum="0ED2F1CE132FD2FB" modified="2011-12-14" version="1">MKNVTSLALLAMATFAVADYDVNHPSSNAPSKRSFGSSSYGGFPNKGGNPPMPDKPYSSKCTTTTTTSTTKTTTVQRSSSTLSCSTSASSSFSTPTKSTSMSTSCSTTASSSVSSSAFTSVSTSVSSTASTTASTSASSSTSSSAYPVSSSSSAKTTTTQLSSTSSSSASSSSSFSSAQTKTVETKTINPSSSKSHKPSQPPQSWTTSTLTLTSTTTFLECPTATPDCPIKKPATTTVVVVTTTVCPVTSATPSPPPPPPKTTAAPPPLPAVSSEPPKTTGAPPPPPPPPPPPPPPASSGSPAPPPPPPPPPKTTMVPQPQPPTTSTTTSAPPIVTAAANAQRAGGVLAAVALAAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NJP7</accession>
    <name>G4NJP7_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_12655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721206.1">
        <property type="nucleotide sequence ID" value="XM_003721158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NJP7"/>
    <dbReference type="GeneID" id="5050529"/>
    <dbReference type="KEGG" id="mgr:MGG_12655"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12655"/>
    <dbReference type="HOGENOM" id="CLU_2427462_0_0_1"/>
    <dbReference type="InParanoid" id="G4NJP7"/>
    <dbReference type="PHI-base" id="PHI:4526"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466711" evidence="1">
        <location>
            <begin position="19"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA46463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="91" mass="9559" checksum="F605C625C39E4203" modified="2011-12-14" version="1">MQFSQILTVLFLGVSVSALPAGGLPGSPGSAVQRCHCPPRGSHAHGSLAAREEAPEAEGDAKISARYTCPNCHKTGKGCDDGWCQVEKTHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKN8</accession>
    <name>G4NKN8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rhodopsin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_10581</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SAT4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721370.1">
        <property type="nucleotide sequence ID" value="XM_003721322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKN8"/>
    <dbReference type="GeneID" id="2682194"/>
    <dbReference type="KEGG" id="mgr:MGG_10581"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10581"/>
    <dbReference type="eggNOG" id="ENOG502SI17">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028200_12_3_1"/>
    <dbReference type="InParanoid" id="G4NKN8"/>
    <dbReference type="OMA" id="GMILMER"/>
    <dbReference type="OrthoDB" id="5378633at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049326">
        <property type="entry name" value="Rhodopsin_dom_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052337">
        <property type="entry name" value="SAT4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048:SF108">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33048">
        <property type="entry name" value="PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20684">
        <property type="entry name" value="Fung_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodopsin" evidence="8">
        <location>
            <begin position="60"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="319"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="406"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="412"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA46627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="442" mass="47963" checksum="D37C042C8291D5A4" modified="2011-12-14" version="1">MIATANLAVMSTNGSEIIGAGVPPPGVTPNFENPSDNLRSVSYVTQTLTLVVVTAFVIVRFYAKHVALGNHWHTEDYFTFATWFLMVGYCITAIYATHFGGGLDQWEVPATLITGYFKACYAATIFYMPMAFCVKIALLALTQRVYGPHKKTIMGIKIFELLLFLYYGSGLIIKIRTCWPIEAYWLGQKDKCLNQDVIILCDSILSVISDLAILILPIPLTWSLELSNRKKLRIMGILCAGGTATAFSIYRLGMILMERNSPNATMTFTKVILSGNAEVGIGLICACLPAITALVLKKTRSTGYYSGNGGYMRSDNDQLGGPGNSKFHTHSHARSGYAAGGSSHNHSVHNHSHSHGGGIVVSRTFDVQRTLKADTDYVVPDKDGGLPLSMLDANGKADQAELVTHAQGVGRSTKSSSIGGLSSNDSDEKLDRQIRAHGGRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>G4NKR3</accession>
    <name>G4NKR3_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_10559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721395.1">
        <property type="nucleotide sequence ID" value="XM_003721347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NKR3"/>
    <dbReference type="SMR" id="G4NKR3"/>
    <dbReference type="GeneID" id="2682172"/>
    <dbReference type="KEGG" id="mgr:MGG_10559"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10559"/>
    <dbReference type="HOGENOM" id="CLU_1816195_0_0_1"/>
    <dbReference type="InParanoid" id="G4NKR3"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003466734" evidence="2">
        <location>
            <begin position="19"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA46652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="142" mass="15231" checksum="1F9FBFFFAEE23A5F" modified="2011-12-14" version="1">MRFIFPLVIAGLAHVALAAPVRSSESAHSIVSRGTEVYGVSTGEVLSKRAAVIAAGAYGDDDDSDDGWGESTAQRNRRKQHEKEARLLKAEEKKRLKEEQAKKRAAQKAEREAQREAKAAMKKQAGEAGQKSGCCGLLPGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>G4NL84</accession>
    <name>G4NL84_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lysine-specific metallo-endopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_09617</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M35 family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721472.1">
        <property type="nucleotide sequence ID" value="XM_003721424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4NL84"/>
    <dbReference type="SMR" id="G4NL84"/>
    <dbReference type="GeneID" id="2680622"/>
    <dbReference type="KEGG" id="mgr:MGG_09617"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_09617"/>
    <dbReference type="HOGENOM" id="CLU_2004377_0_0_1"/>
    <dbReference type="InParanoid" id="G4NL84"/>
    <dbReference type="OMA" id="MADKAYY"/>
    <dbReference type="OrthoDB" id="412874at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050414">
        <property type="entry name" value="Fungal_M35_metalloproteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029463">
        <property type="entry name" value="Lys_MEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37016:SF3">
        <property type="entry name" value="NEUTRAL PROTEASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14521">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01351">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lysine-specific metallo-endopeptidase" evidence="8">
        <location>
            <begin position="6"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA46729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="124" mass="14168" checksum="F9A1F4308EBA1EA4" modified="2011-12-14" version="1">MADKAYYAANKNGSLFRRFFKTNDPDDAVASEGGSCTPDSTHAYVHDKQEMYICPYFFEHDLTERASTLIHELTHHKDIKGTFDYDTYKYDGIMGLTSEQNLMHADTYSIFAVYATNTYSSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>G5EH47</accession>
    <name>G5EH47_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGCH7_ch7g1064</name>
        <name evidence="3" type="ORF">MGG_17860</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15</strain>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">70-15</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA45796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720539.1">
        <property type="nucleotide sequence ID" value="XM_003720491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EH47"/>
    <dbReference type="GeneID" id="12984716"/>
    <dbReference type="KEGG" id="mgr:MGG_17860"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_17860"/>
    <dbReference type="eggNOG" id="ENOG502SY9M">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_192408_0_0_1"/>
    <dbReference type="OMA" id="HTKKVAP"/>
    <dbReference type="OrthoDB" id="3439627at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EAQ71657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA45796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="76" mass="7615" checksum="33A6014ADC529EE7" modified="2011-12-14" version="1">MPRDGSGRAHNDVEDKPEIAHGVDQPGSNVDRSNKAAAMPEGEKGMAIEGMNASGGSSQGLSRGPNVGQGKGASAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="83" xmlns="https://uniprot.org/uniprot">
    <accession>G5EHM8</accession>
    <name>G5EHM8_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable endonuclease LCL3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Probable endonuclease lcl3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGCH7_ch7g348</name>
        <name evidence="11" type="ORF">MGG_12646</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15</strain>
            <strain evidence="12">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ70941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM001237">
        <property type="protein sequence ID" value="EHA46423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003721166.1">
        <property type="nucleotide sequence ID" value="XM_003721118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EHM8"/>
    <dbReference type="SMR" id="G5EHM8"/>
    <dbReference type="STRING" id="242507.G5EHM8"/>
    <dbReference type="GeneID" id="5050519"/>
    <dbReference type="KEGG" id="mgr:MGG_12646"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_12646"/>
    <dbReference type="eggNOG" id="KOG2039">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005966_1_0_1"/>
    <dbReference type="OMA" id="ARCADHH"/>
    <dbReference type="OrthoDB" id="10023235at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031332">
        <property type="term" value="C:RNAi effector complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00175">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000010">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000018">
        <property type="entry name" value="Serine/threonine-protein kinase 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000001">
        <property type="entry name" value="Staphylococcal nuclease domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000019">
        <property type="entry name" value="Transcription factor (Snd1/p100), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000030">
        <property type="entry name" value="Transcription factor (Snd1/p100), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016685">
        <property type="entry name" value="Silence_cplx_Nase-comp_TudorSN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF2">
        <property type="entry name" value="STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017179">
        <property type="entry name" value="RISC-Tudor-SN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TNase-like" evidence="9">
        <location>
            <begin position="4"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="9">
        <location>
            <begin position="166"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="9">
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
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            <dbReference type="EMBL" id="EAQ70941.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="EHA46423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="894" mass="98469" checksum="8FB69B7005E651E4" modified="2011-12-14" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="60" xmlns="https://uniprot.org/uniprot">
    <accession>G5EI79</accession>
    <name>G5EI79_PYRO7</name>
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        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MGCH7_ch7g906</name>
        <name evidence="8" type="ORF">MGG_03102</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">70-15</strain>
            <strain evidence="9">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">70-15</strain>
        </source>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003720570.1">
        <property type="nucleotide sequence ID" value="XM_003720522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5EI79"/>
    <dbReference type="SMR" id="G5EI79"/>
    <dbReference type="GeneID" id="2682655"/>
    <dbReference type="KEGG" id="mgr:MGG_03102"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_03102"/>
    <dbReference type="eggNOG" id="ENOG502QWBF">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013756_4_1_1"/>
    <dbReference type="OMA" id="FASKSIM"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="335"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="377"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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    </feature>
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    </feature>
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        <location>
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    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
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        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="EAQ71499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="EHA45827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2006-03-07" modified="2025-10-08" version="77" xmlns="https://uniprot.org/uniprot">
    <accession>Q2KEL7</accession>
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        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
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    </protein>
    <gene>
        <name evidence="9" type="ORF">MGCH7_ch7g1019</name>
        <name evidence="10" type="ORF">MGG_10255</name>
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    <organism evidence="9">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
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        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
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            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15</strain>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2005-01" db="EMBL/GenBank/DDBJ databases">
            <title>The sequence of Magnaporthe grisea chromosome 7.</title>
            <authorList>
                <person name="Thon M.R."/>
                <person name="Pan H."/>
                <person name="Diener A."/>
                <person name="Papalas J."/>
                <person name="Taro A."/>
                <person name="Mitchell T."/>
                <person name="Dean R.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">70-15</strain>
        </source>
    </reference>
    <reference evidence="10" key="3">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <person name="Ma L.-J."/>
                <person name="Dean R.A."/>
                <person name="Gowda M."/>
                <person name="Nunes C."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CM000230">
        <property type="protein sequence ID" value="EAQ71612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JH165178">
        <property type="protein sequence ID" value="KYQ30526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_016846030.1">
        <property type="nucleotide sequence ID" value="XM_016990509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q2KEL7"/>
    <dbReference type="SMR" id="Q2KEL7"/>
    <dbReference type="FunCoup" id="Q2KEL7">
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    </dbReference>
    <dbReference type="GeneID" id="2681816"/>
    <dbReference type="KEGG" id="mgr:MGG_10255"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_10255"/>
    <dbReference type="eggNOG" id="KOG2533">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_1_1"/>
    <dbReference type="OMA" id="DPRWRFE"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000068">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF22">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G11320)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="64"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EAQ71612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KYQ30526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="509" mass="55601" checksum="7DF0BDBE465BDFAA" modified="2006-03-07" version="1">MSDFPASREPAVAHHGDDERPSNGDDSKTVSEDKKDHTGPPSDSDTELGEMNEKALLRKIDWKLLPAVGILYLLSFLDRSNVGNARIEGLLDDLGMSGDQYLTGLTIYFVGYVIFEIPCNIILKRTTPQLWLPTLTVAWGIVATLMGIVTNPAGFFAARFFLGVTESGLFPGVVYYFSMWYQRRERQYRIALFFSGAALAGAFGGILAWGIGHMRGVVWANSWRWIFILEGIATVAVALAAYFFIQNYPDTAKFLSPAEKRSIHARLAADSDATLDERFNWANVTAALRDPACWLYGLGFHTVSLPLYTLSLFLPTIIANLGYTSAVAQLLTIPPYAFAFVTTLTVASLSERYRRRALPIAGSAALAIVGYVVLLANTNPVARPGVSYLGTFLAAGGIYPAVALVLSWPAINVSGQTKRAVANGMQISVGNLGAVLGTQLYRSGDGPRFIVGHSFALGYLAANIIVVLTLWRLLSRENARREGIAEEVKAVGALEDWQGDTDPRWRFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-05-15" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>A4QPR8</accession>
    <name>A4QPR8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_13132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710486.1">
        <property type="nucleotide sequence ID" value="XM_003710438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A4QPR8"/>
    <dbReference type="GeneID" id="5051533"/>
    <dbReference type="KEGG" id="mgr:MGG_13132"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_13132"/>
    <dbReference type="eggNOG" id="ENOG502T6KC">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_121068_0_0_1"/>
    <dbReference type="InParanoid" id="A4QPR8"/>
    <dbReference type="OMA" id="CFVPQCT"/>
    <dbReference type="OrthoDB" id="5236000at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002672800" evidence="1">
        <location>
            <begin position="19"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA57874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="156" mass="16062" checksum="D2B2B5B8975F4297" modified="2007-05-15" version="1">MLSLHVLFLGALATFATAQQITLTPTTIRGGACPITLTSTIKQTQTQTQTQTQTVTSVSTTTRTSVSTVTSTSTVRQTITSVATVTRACVSCPTLTATATACRTCLVPGCTTTVAVSKPCGCDNLATTSIDLGCDAPNVCNRIGCKTVYDIKTAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKB8</accession>
    <name>G4MKB8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_02513</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709321.1">
        <property type="nucleotide sequence ID" value="XM_003709273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKB8"/>
    <dbReference type="GeneID" id="2681610"/>
    <dbReference type="KEGG" id="mgr:MGG_02513"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_02513"/>
    <dbReference type="eggNOG" id="ENOG502S3VI">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099932_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKB8"/>
    <dbReference type="OMA" id="ILMAWAI"/>
    <dbReference type="OrthoDB" id="3358048at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA56709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="246" mass="26292" checksum="75162985D59AD605" modified="2011-12-14" version="1">MADVPRSATARLRKTFQYPTDDSSSSTPEVLDEEEQDNLIQSLADQNAARNAQFRIAMLALPVLSTLPYLVILFRRPEASLILPTLLSISSLASTTWLLYAQDPTETGIAALDSWARGAGLDNSNGNNPPFSPLRRAPGGSRRRRLSSFSAAAGGGVGVYGRGYRSPLETYLPLLNAGLCALLLLMAVLIALAPPEGRTAPEHVGRVMLACLPAVVYAVVIAAKLVMSSVDPERDLTGLKYENKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>G4MKK1</accession>
    <name>G4MKK1_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_04465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710996.1">
        <property type="nucleotide sequence ID" value="XM_003710948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MKK1"/>
    <dbReference type="GeneID" id="2678163"/>
    <dbReference type="KEGG" id="mgr:MGG_04465"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_04465"/>
    <dbReference type="eggNOG" id="ENOG502RF9B">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045142_0_0_1"/>
    <dbReference type="InParanoid" id="G4MKK1"/>
    <dbReference type="OMA" id="KCQEMMQ"/>
    <dbReference type="OrthoDB" id="5234702at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="345" mass="37872" checksum="5E9365E47F8584C1" modified="2011-12-14" version="1">MAATSEPFTGTSLPFKPQIPITPPPDCLNFAIKCPELSTKSTPLSREAPAAMDPKIKTAKPHIETPATSVTPSTDSTQSSSASSQSPNLDSSSSTTPTNANTTSPTPSMDTRHLALISRIAAYYQQRSQAIANYQHQKCQAWANLQRAKCQEMTQAAMLVVAWYVRDRIQRRRKREKRQFRRGLSERSAATAPTPAGVGKKKRVEATVDKWIGHVPKDVLPSPNTAALDKPIDTDELGFSIDAEPSPTDGDDKLFAVADGMIKSQLARIEVPLLGALDFAADDDDSDSESDFEEVRRWRPGGEDDGDLERAAEQDDDDEDDYSYEYDDDDDDDDMEDLTGEVVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>G4ML02</accession>
    <name>G4ML02_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MGG_08614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711041.1">
        <property type="nucleotide sequence ID" value="XM_003710993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4ML02"/>
    <dbReference type="STRING" id="242507.G4ML02"/>
    <dbReference type="GeneID" id="2679043"/>
    <dbReference type="KEGG" id="mgr:MGG_08614"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_08614"/>
    <dbReference type="eggNOG" id="KOG2084">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028281_6_0_1"/>
    <dbReference type="InParanoid" id="G4ML02"/>
    <dbReference type="OMA" id="DERHETS"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053185">
        <property type="entry name" value="SET_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332:SF6">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47332">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465767" description="SET domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="86"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="EHA58429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="399" mass="43998" checksum="8E5346497693E180" modified="2011-12-14" version="1">MQPSIASILAFLIVSANAECQKTSPLDAVQETTCGVHLFDQDSKWQGPESCLGEYCIYWNSEFNNGMGIAAVTTAEHAQSIAKFTEEMQLLQDDPPYFKADIPGKGKGVIAKRKIALGETIMILPPTLLVSDAAYQAFGGARKAKGNALYSKALEKVSATAREEFQGLHGLDAAMKLDKNGFTVYVGYTEESQHLGVYAQAAAINHDCRPSINYRLNDITQTTTAVREIQPGEELSVSYVDLMLPHKQRRQRLRDWGFDCKCSKCTASAAAIARSDENLSMIQFLESALDSPNSTVTGATGEQLVALYEEERLDIYLGPTYTRAALNYGLFGEKEKAVEYAKKAIAALERQYGPYAADIPSMQALRDEPEKHWSWGLRKLPSLKIPIPDDIPKPPMKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLM6</accession>
    <name>G4MLM6_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="7">3.4.21.92</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MGG_06757</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="7"/>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709471.1">
        <property type="nucleotide sequence ID" value="XM_003709423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLM6"/>
    <dbReference type="SMR" id="G4MLM6"/>
    <dbReference type="STRING" id="242507.G4MLM6"/>
    <dbReference type="MEROPS" id="S14.001"/>
    <dbReference type="GeneID" id="2684930"/>
    <dbReference type="KEGG" id="mgr:MGG_06757"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_06757"/>
    <dbReference type="eggNOG" id="KOG0840">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058707_3_1_1"/>
    <dbReference type="InParanoid" id="G4MLM6"/>
    <dbReference type="OMA" id="RDYWMKA"/>
    <dbReference type="OrthoDB" id="2017408at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000002">
        <property type="entry name" value="ATP-dependent Clp protease proteolytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001368">
        <property type="entry name" value="PRK00277.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF11">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0720">Serine protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EHA56859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="274" mass="29605" checksum="00485D68D1F756D5" modified="2011-12-14" version="1">MNIPRIFRHTLTRGAPSVSRVAACQRASLNLSNARSFSHSRPPQAGVPMPLVTEVTAGGWRTSDIFSKLLQERIVCLNGPIDDWTQASVTAQLLWLEQDSPHKPITLYINSPGGQVSSGLAIYDTMNYISSPVHTVCVGMAASMGAILLLGGAAGQRYALPHSQIMVHQPLGSTQGQASDIIIYAKQITRIRSQINDIMRRHLNTAAGRERFAAQEVDEMMERDKYLTADEAVELGIVDKILTSRSDAVASALNDATGGRSAAAPAEAQDEKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLT1</accession>
    <name>G4MLT1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">MGG_05456</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710321.1">
        <property type="nucleotide sequence ID" value="XM_003710273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLT1"/>
    <dbReference type="STRING" id="242507.G4MLT1"/>
    <dbReference type="GeneID" id="2675884"/>
    <dbReference type="KEGG" id="mgr:MGG_05456"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05456"/>
    <dbReference type="eggNOG" id="ENOG502SXQX">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063084_5_1_1"/>
    <dbReference type="InParanoid" id="G4MLT1"/>
    <dbReference type="OMA" id="VINCLAT"/>
    <dbReference type="OrthoDB" id="5244132at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051735">
        <property type="entry name" value="CFEM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008427">
        <property type="entry name" value="Extracellular_membr_CFEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928">
        <property type="entry name" value="CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G14090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37928:SF2">
        <property type="entry name" value="GPI ANCHORED CFEM DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G10580)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05730">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52012">
        <property type="entry name" value="CFEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="6 15" id="KW-0349">Heme</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465105" description="CFEM domain-containing protein" evidence="17">
        <location>
            <begin position="17"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="CFEM" evidence="18">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="93"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS52012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EHA57709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="194" mass="17961" checksum="A98AC6F28D63D476" modified="2011-12-14" version="1">MKYTAVLAVLAGIAAAQSINDVPECARSCISTAATAAGCGASDLSCMCKNRDKIVSGPAATCALNSCQEKIGEVITSLQTLCAAVEAGAGASSAAPPPTSSAAPPASSAAPPASSAAPPASSAAPPASSAVPSSTQAPSSAAPTTTKATTASSGVAKPTSGSGSASAPPTSPTAGAATLGMSGFAVLALGALAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>G4MLW8</accession>
    <name>G4MLW8_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MGG_16570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA58535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003711147.1">
        <property type="nucleotide sequence ID" value="XM_003711099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MLW8"/>
    <dbReference type="GeneID" id="12986945"/>
    <dbReference type="KEGG" id="mgr:MGG_16570"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16570"/>
    <dbReference type="HOGENOM" id="CLU_2543011_0_0_1"/>
    <dbReference type="InParanoid" id="G4MLW8"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5003465240" evidence="1">
        <location>
            <begin position="19"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EHA58535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="83" mass="9351" checksum="0B5CB1B79481C363" modified="2011-12-14" version="1">MQLSKIYLLALWATGATALFSEEENLHMIKNGEIPPDTKDYHGNPLLKLPGNAHCYLIRHPQFCDKIIPCVWAGPLGCIIQDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>G4MM76</accession>
    <name>G4MM76_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MGG_05503</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003710369.1">
        <property type="nucleotide sequence ID" value="XM_003710321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MM76"/>
    <dbReference type="SMR" id="G4MM76"/>
    <dbReference type="STRING" id="242507.G4MM76"/>
    <dbReference type="GeneID" id="2675817"/>
    <dbReference type="KEGG" id="mgr:MGG_05503"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_05503"/>
    <dbReference type="eggNOG" id="ENOG502RIYK">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036094_0_1_1"/>
    <dbReference type="InParanoid" id="G4MM76"/>
    <dbReference type="OMA" id="NGWVLYK"/>
    <dbReference type="OrthoDB" id="5197598at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015099">
        <property type="term" value="F:nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004688">
        <property type="entry name" value="Ni/Co_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611:SF0">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0533">Nickel</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EHA57757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="394" mass="42252" checksum="07A89D67782BCD5F" modified="2011-12-14" version="1">MARFNFNSLPGWLQSAPPAAIRIILVLILINAAVWIAAGIILHFHPALIAPAALSYALGLRHALDADHISAIDLMTRRLIASGQRPVTVGTFFSLGHSTIVVVTCIVVAATSGALRDRFDDFTRVGNIVGTSVSAAFLLLLSAGNGWVLYRLVCRLREVLAERRRRGAVLGREDGAGADVDDAGAAAGLGLDGVGFLSRVFRRLFDVIDRPWKMFPLGVMFGLGFDTSSEIAILGITSLQGAAGTSLWLILIFPVLFTAGMCLVDTSDGALMMGLYSSKAFSRDQVAILYYSIVLTGITVFISAFIGMIQLFSLIQNVADPQGGFWDGVGAISDNFDIIGASICGLFLVIGIGSVVVYRPWRRRMERRMEPPLVANGGEEGYASPVRSEQNESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>G4MML0</accession>
    <name>G4MML0_PYRO7</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MGG_16199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA56988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709600.1">
        <property type="nucleotide sequence ID" value="XM_003709552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MML0"/>
    <dbReference type="GeneID" id="12985218"/>
    <dbReference type="KEGG" id="mgr:MGG_16199"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_16199"/>
    <dbReference type="HOGENOM" id="CLU_2498283_0_0_1"/>
    <dbReference type="InParanoid" id="G4MML0"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EHA56988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000009058"/>
        </source>
    </evidence>
    <sequence length="86" mass="10160" checksum="6201FF0E7D6946D8" modified="2011-12-14" version="1">MSYLRPEQYSYQERVRETRVRWVVEELIEPASQLGWIEAHSFRCYLEATRGSSTLGTLARLRFHRRQAWFGSIPTVDGAKIWISVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2026-01-28" version="68" xmlns="https://uniprot.org/uniprot">
    <accession>G4MMY1</accession>
    <name>G4MMY1_PYRO7</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">AP-1 complex subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MGG_11801</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)</name>
        <name type="common">Rice blast fungus</name>
        <name type="synonym">Magnaporthe oryzae</name>
        <dbReference type="NCBI Taxonomy" id="242507"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Dikarya</taxon>
            <taxon>Ascomycota</taxon>
            <taxon>Pezizomycotina</taxon>
            <taxon>Sordariomycetes</taxon>
            <taxon>Sordariomycetidae</taxon>
            <taxon>Magnaporthales</taxon>
            <taxon>Pyriculariaceae</taxon>
            <taxon>Pyricularia</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2005" name="Nature" volume="434" first="980" last="986">
            <title>The genome sequence of the rice blast fungus Magnaporthe grisea.</title>
            <authorList>
                <person name="Dean R.A."/>
                <person name="Talbot N.J."/>
                <person name="Ebbole D.J."/>
                <person name="Farman M.L."/>
                <person name="Mitchell T.K."/>
                <person name="Orbach M.J."/>
                <person name="Thon M."/>
                <person name="Kulkarni R."/>
                <person name="Xu J.R."/>
                <person name="Pan H."/>
                <person name="Read N.D."/>
                <person name="Lee Y.H."/>
                <person name="Carbone I."/>
                <person name="Brown D."/>
                <person name="Oh Y.Y."/>
                <person name="Donofrio N."/>
                <person name="Jeong J.S."/>
                <person name="Soanes D.M."/>
                <person name="Djonovic S."/>
                <person name="Kolomiets E."/>
                <person name="Rehmeyer C."/>
                <person name="Li W."/>
                <person name="Harding M."/>
                <person name="Kim S."/>
                <person name="Lebrun M.H."/>
                <person name="Bohnert H."/>
                <person name="Coughlan S."/>
                <person name="Butler J."/>
                <person name="Calvo S."/>
                <person name="Ma L.J."/>
                <person name="Nicol R."/>
                <person name="Purcell S."/>
                <person name="Nusbaum C."/>
                <person name="Galagan J.E."/>
                <person name="Birren B.W."/>
            </authorList>
            <dbReference type="PubMed" id="15846337"/>
            <dbReference type="DOI" id="10.1038/nature03449"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">70-15 / ATCC MYA-4617 / FGSC 8958</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="2011-05" db="EMBL/GenBank/DDBJ databases">
            <title>The Genome Sequence of Magnaporthe oryzae 70-15.</title>
            <authorList>
                <consortium name="The Broad Institute Genome Sequencing Platform"/>
                <person name="Ma L.-J."/>
                <person name="Dead R."/>
                <person name="Young S.K."/>
                <person name="Zeng Q."/>
                <person name="Gargeya S."/>
                <person name="Fitzgerald M."/>
                <person name="Haas B."/>
                <person name="Abouelleil A."/>
                <person name="Alvarado L."/>
                <person name="Arachchi H.M."/>
                <person name="Berlin A."/>
                <person name="Brown A."/>
                <person name="Chapman S.B."/>
                <person name="Chen Z."/>
                <person name="Dunbar C."/>
                <person name="Freedman E."/>
                <person name="Gearin G."/>
                <person name="Gellesch M."/>
                <person name="Goldberg J."/>
                <person name="Griggs A."/>
                <person name="Gujja S."/>
                <person name="Heiman D."/>
                <person name="Howarth C."/>
                <person name="Larson L."/>
                <person name="Lui A."/>
                <person name="MacDonald P.J.P."/>
                <person name="Mehta T."/>
                <person name="Montmayeur A."/>
                <person name="Murphy C."/>
                <person name="Neiman D."/>
                <person name="Pearson M."/>
                <person name="Priest M."/>
                <person name="Roberts A."/>
                <person name="Saif S."/>
                <person name="Shea T."/>
                <person name="Shenoy N."/>
                <person name="Sisk P."/>
                <person name="Stolte C."/>
                <person name="Sykes S."/>
                <person name="Yandava C."/>
                <person name="Wortman J."/>
                <person name="Nusbaum C."/>
                <person name="Birren B."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain>70-15</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Adaptor protein complex 1 (AP-1) is a heterotetramer composed of two large adaptins (gamma-type subunit APL4 and beta-type subunit APL2), a medium adaptin (mu-type subunit APM1) and a small adaptin (sigma-type subunit APS1). AP-1 interacts with clathrin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CM001231">
        <property type="protein sequence ID" value="EHA57003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_003709615.1">
        <property type="nucleotide sequence ID" value="XM_003709567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G4MMY1"/>
    <dbReference type="SMR" id="G4MMY1"/>
    <dbReference type="FunCoup" id="G4MMY1">
        <property type="interactions" value="669"/>
    </dbReference>
    <dbReference type="STRING" id="242507.G4MMY1"/>
    <dbReference type="GeneID" id="5049589"/>
    <dbReference type="KEGG" id="mgr:MGG_11801"/>
    <dbReference type="VEuPathDB" id="FungiDB:MGG_11801"/>
    <dbReference type="eggNOG" id="KOG1062">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003824_0_0_1"/>
    <dbReference type="InParanoid" id="G4MMY1"/>
    <dbReference type="OMA" id="AICAMRI"/>
    <dbReference type="OrthoDB" id="28053at2759"/>
    <dbReference type="Proteomes" id="UP000009058">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030121">
        <property type="term" value="C:AP-1 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016482">
        <property type="term" value="P:cytosolic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000030">
        <property type="entry name" value="AP-1 complex subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017107">
        <property type="entry name" value="AP1_complex_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008153">
        <property type="entry name" value="GAE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037094">
        <property type="entry name" value="AP1_complex_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50180">
        <property type="entry name" value="GAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GAE" evidence="12">
        <location>
            <begin position="734"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="603"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="661"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="613"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="691"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    <